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Cheap flights from Columbus Airport to Key West from $127

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to Key West departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus Airport to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:15 am - 6:19 pm
CMH
-
EYW
7h 04m
1 stop
American Airlines Logo
7:42 pm - 12:59 am
EYW
-
CMH
5h 17m
1 stop
$251American Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
2:51 pm - 12:26 pm
CMH
-
EYW
21h 35m
2 stops
Multiple Airlines Logo
11:51 am - 11:53 pm
EYW
-
CMH
12h 02m
1 stop
$255Multiple Airlines
Sun, Mar 8 - Wed, Mar 11
American Airlines Logo
9:30 am - 4:49 pm
CMH
-
EYW
7h 19m
2 stops
American Airlines Logo
7:42 pm - 12:59 am
EYW
-
CMH
5h 17m
1 stop
$256American Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
2:51 pm - 12:26 pm
CMH
-
EYW
21h 35m
2 stops
Multiple Airlines Logo
11:51 am - 11:53 pm
EYW
-
CMH
12h 02m
1 stop
$260Multiple Airlines
Sun, Mar 8 - Wed, Mar 11
American Airlines Logo
6:00 am - 1:27 pm
CMH
-
EYW
7h 27m
1 stop
American Airlines Logo
5:53 pm - 11:52 pm
EYW
-
CMH
5h 59m
1 stop
$265American Airlines
Wed, May 20 - Wed, May 27
Multiple Airlines Logo
6:05 am - 12:26 pm
CMH
-
EYW
6h 21m
1 stop
Multiple Airlines Logo
9:49 am - 11:42 am
EYW
-
CMH
25h 53m
2 stops
$275Multiple Airlines
Mon, Mar 23 - Mon, Mar 30
Multiple Airlines Logo
2:51 pm - 12:26 pm
CMH
-
EYW
21h 35m
2 stops
Multiple Airlines Logo
11:51 am - 11:19 pm
EYW
-
CMH
11h 28m
1 stop
$276Multiple Airlines
Sun, Mar 22 - Wed, Mar 25
Multiple Airlines Logo
1:07 pm - 11:11 am
CMH
-
EYW
22h 04m
2 stops
Multiple Airlines Logo
12:25 pm - 9:41 am
EYW
-
CMH
21h 16m
1 stop
$277Multiple Airlines
Tue, Mar 24 - Sun, Mar 29
American Airlines Logo
6:00 am - 1:42 pm
CMH
-
EYW
7h 42m
1 stop
American Airlines Logo
2:29 pm - 11:31 pm
EYW
-
CMH
9h 02m
1 stop
$279American Airlines
Wed, Apr 22 - Tue, Apr 28
Multiple Airlines Logo
2:51 pm - 12:26 pm
CMH
-
EYW
21h 35m
2 stops
Multiple Airlines Logo
1:06 pm - 8:30 am
EYW
-
CMH
19h 24m
1 stop
$280Multiple Airlines
Sun, Mar 22 - Fri, Mar 27

American Airlines flights from Columbus Airport to Key West

Our best American Airlines deals on Columbus Airport to Key West flight tickets
American Airlines
Mar 17
CMH11:15 amColumbus
7h 04m
1 stop
EYW6:19 pmKey West
Mar 24
EYW7:42 pmKey West
5h 17m
1 stop
CMH12:59 amColumbus
$251
American Airlines
Mar 17
CMH9:30 amColumbus
7h 19m
2 stops
EYW4:49 pmKey West
Mar 24
EYW7:42 pmKey West
5h 17m
1 stop
CMH12:59 amColumbus
$256
American Airlines
May 20
CMH6:00 amColumbus
7h 27m
1 stop
EYW1:27 pmKey West
May 27
EYW5:53 pmKey West
5h 59m
1 stop
CMH11:52 pmColumbus
$265

Spirit Airlines flights from Columbus Airport to Key West

Our best Spirit Airlines deals on Columbus Airport to Key West flight tickets
Spirit Airlines
Mar 19
CMH5:45 amColumbus
5h 45m
1 stop
EYW11:30 amKey West
Mar 26
EYW12:25 pmKey West
10h 24m
1 stop
CMH10:49 pmColumbus
$281
Spirit Airlines
May 8
CMH6:00 amColumbus
5h 11m
1 stop
EYW11:11 amKey West
May 15
EYW12:06 pmKey West
9h 46m
1 stop
CMH9:52 pmColumbus
$306
Spirit Airlines
Mar 22
CMH10:40 amColumbus
26h 57m
1 stop
EYW1:37 pmKey West
Mar 29
EYW12:25 pmKey West
21h 16m
1 stop
CMH9:41 amColumbus
$321

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Columbus Airport to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 3/17

11:15 am-6:19 pm

1 stop7h 04m

Key West

Tue 3/24

7:42 pm-12:59 am

1 stop5h 17m

$251

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 3/8

2:51 pm-12:26 pm

2 stops21h 35m

Key West

Wed 3/11

11:51 am-11:53 pm

1 stop12h 02m

$255

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 3/17

9:30 am-4:49 pm

2 stops7h 19m

Key West

Tue 3/24

7:42 pm-12:59 am

1 stop5h 17m

$256

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 3/8

2:51 pm-12:26 pm

2 stops21h 35m

Key West

Wed 3/11

11:51 am-11:53 pm

1 stop12h 02m

$260

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 5/20

6:00 am-1:27 pm

1 stop7h 27m

Key West

Wed 5/27

5:53 pm-11:52 pm

1 stop5h 59m

$265

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 3/23

6:05 am-12:26 pm

1 stop6h 21m

Key West

Mon 3/30

9:49 am-11:42 am

2 stops25h 53m

$275

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 3/22

2:51 pm-12:26 pm

2 stops21h 35m

Key West

Wed 3/25

11:51 am-11:19 pm

1 stop11h 28m

$276

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 3/24

1:07 pm-11:11 am

2 stops22h 04m

Key West

Sun 3/29

12:25 pm-9:41 am

1 stop21h 16m

$277

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 4/22

6:00 am-1:42 pm

1 stop7h 42m

Key West

Tue 4/28

2:29 pm-11:31 pm

1 stop9h 02m

$279

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 3/22

2:51 pm-12:26 pm

2 stops21h 35m

Key West

Fri 3/27

1:06 pm-8:30 am

1 stop19h 24m

$280

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbus Airport to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Columbus Airport to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $309. If you are unable to visit Key West during the month of September, then departing from Columbus Airport during the month February is also very affordable. Most momondo users find prices during this month for around $319.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Columbus Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $382 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Columbus Airport for as low as $268 on momondo.

How have Columbus Airport to Key West flight prices changed over time?

As of February 2026, prices for Columbus Airport to Key West flights are approximately 34% cheaper when compared to flights at the same time last year.

When to book flights from Columbus Airport to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Columbus Airport to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbus Airport to Key West (CMH to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to Key West

Fastest flight time

4h 21m

Direct flights

None
The fastest flight from Columbus Airport to Key West takes 4h 21m
There are no direct flights from Columbus Airport to Key West. There are no popular flight routes from Columbus Airport to Key West.
Search flight deals

  • How far is Columbus to Key West by plane?

    The straight-line distance from Columbus to Key West is 1068.2 mi. In terms of flight time, this usually takes a little over 4h 21m.

  • When did momondo last update prices for flights from Columbus Airport to Key West Airport?

    Prices for flights from Columbus Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Columbus Airport to Key West Airport?

  • How old do you have to be to fly from Columbus Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbus Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Columbus Airport to Key West?

Best airlines flying from Columbus Airport to Key West

Compare and see reviews for airlines that fly from Columbus Airport to Key West with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $96Free CancellationRating
6.3
8,489 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $165Free CancellationRating
7.4
9,342 reviews
Search United Airlines flights
DeltaPriceFrom $250Free CancellationRating
7.9
8,236 reviews
Search Delta flights
American AirlinesPriceFrom $251Free CancellationRating
7.2
11,339 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Key West?

It is quick and easy to find Columbus to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbus to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Columbus on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbus to Key West?

Once you have performed a search for Columbus to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Columbus to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Columbus and alert you when they change.

An easier way to manage your Key West trip

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