Cheap flights from Jacksonville to Missouri from $48

In general, October is the cheapest month to fly from Jacksonville to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $353. If you aren’t able to travel to Missouri during the month of October, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $353.

The cheapest day to depart from Jacksonville to Missouri is on a Wednesday when prices can be found for as low as $395. Flights from Jacksonville to Missouri on a Sunday will generally be more expensive and average around $447. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Jacksonville to Missouri at noon for as low as $370. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the morning, with an average ticket price of $438. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Jacksonville to Lambert-St Louis for the best Jacksonville - Missouri flight prices

You are more likely to see cheaper flights to Missouri from Jacksonville when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $378 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Jacksonville for as low as $296 on momondo.

There is only 1 cabin class available to choose from on Jacksonville to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

American Airlines, Southwest, and United Airlines are the most popular carriers operating from Jacksonville to Missouri

Delta, Southwest and American Airlines are the top three most popular airlines that fly to Missouri from Jacksonville according to our data. Delta is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 4 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

As of October 2026, there are 1 flights per day flying from Jacksonville to Missouri. The most common time of day flights depart is 5:00AM, with 60% of flights taking off in the morning.

The number of flights available between Jacksonville and Missouri is 7 per week as of October 2026. The most frequent departure day is Tue, with 29% of weekly flights leaving on this day.