How long is the flight from Iowa to South Carolina?

Flight times vary depending on what airport in Iowa you fly out of and what airport in South Carolina you fly into. For example, flying from Des Moines to Charleston takes 4h 18m on average. On the other hand, flying from Cedar Rapids to Charleston takes 4h 32m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

What is the cheapest airline that flies from Iowa to South Carolina?

Frontier, Southwest, and Delta are the most popular carriers operating from Iowa to South Carolina

How many flights depart from Iowa to South Carolina on average per week?

48 flights are operational weekly from Iowa to South Carolina as of February 2026. The most popular departure day for this route is Mon, with 19% of flights per week taking off on this day.

What airlines fly to South Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to South Carolina from Iowa according to our data. American Airlines is the first choice among our users, with 70% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Iowa to South Carolina?

Prices for flights from Iowa to South Carolina are updated daily.

How many operators does momondo search for flights from Iowa to South Carolina?

As of February 2026, there are 4 operators available to choose from for flights from Iowa to South Carolina.

How old do you have to be to fly from Iowa to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$70 Cheap Flights from Iowa to South Carolina in 2026

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Find the cheapest flights from Iowa to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:04 pm - 6:54 pm

DSM

CLT

27h 50m

1 stop

6:18 pm - 1:09 pm

CLT

DSM

19h 51m

1 stop

$162Frontier

Mon, Apr 20 - Thu, Apr 23

2:04 pm - 4:56 pm

DSM

CLT

25h 52m

1 stop

6:18 pm - 1:09 pm

CLT

DSM

19h 51m

1 stop

$192Frontier

Fri, Apr 17 - Sun, Apr 19

8:03 pm - 8:06 am

DSM

CLT

11h 03m

1 stop

11:22 am - 12:52 pm

CLT

DSM

2h 30mnonstop

$249American Airlines

Mon, Apr 27 - Tue, Apr 28

11:40 am - 5:11 pm

DSM

CLT

4h 31m

1 stop

8:05 am - 2:24 pm

CLT

DSM

7h 19m

1 stop

$260United Airlines

Wed, May 13 - Sat, May 16

6:15 am - 2:08 pm

DSM

CLT

6h 53m

2 stops

8:05 am - 2:24 pm

CLT

DSM

7h 19m

1 stop

$266United Airlines

Wed, May 13 - Sat, May 16

3:35 pm - 8:55 pm

OMA

CLT

4h 20m

1 stop

6:20 pm - 10:20 pm

CLT

OMA

5h 00m

1 stop

$268Southwest

Wed, Apr 15 - Wed, Apr 22

4:48 pm - 10:50 pm

CID

MYR

5h 02m

1 stop

4:52 pm - 11:58 pm

MYR

CID

8h 06m

1 stop

$269American Airlines

Sat, Apr 4 - Thu, Apr 9

3:35 pm - 8:55 pm

OMA

CLT

4h 20m

1 stop

7:35 am - 3:40 pm

CLT

OMA

9h 05m

2 stops

$273Southwest

Wed, Apr 15 - Wed, Apr 22

5:45 am - 11:20 am

CID

SAV

4h 35m

1 stop

11:00 am - 9:50 pm

SAV

CID

11h 50m

2 stops

$281Delta

Sun, Aug 23 - Tue, Sep 15

5:45 am - 11:24 am

CID

CHS

4h 39m

1 stop

4:30 pm - 9:50 pm

CHS

CID

6h 20m

1 stop

$294Delta

Wed, Jun 24 - Tue, Jun 30

Southwest flights from Iowa to South Carolina

Our best Southwest deals on Iowa to South Carolina flight tickets

Southwest

Apr 18

DSM5:35 amDes Moines

5h 00m

1 stop

CLT11:35 amCharlotte Douglas

Apr 19

CLT4:50 pmCharlotte Douglas

6h 30m

1 stop

DSM10:20 pmDes Moines

$211

Southwest

Apr 18

DSM6:40 amDes Moines

13h 30m

2 stops

CLT9:10 pmCharlotte Douglas

Apr 19

CLT4:50 pmCharlotte Douglas

6h 30m

1 stop

DSM10:20 pmDes Moines

$222

Southwest

Apr 15

OMA3:35 pmOmaha Eppley Airfield

4h 20m

1 stop

CLT8:55 pmCharlotte Douglas

Apr 22

CLT6:20 pmCharlotte Douglas

5h 00m

1 stop

OMA10:20 pmOmaha Eppley Airfield

$268

United Airlines flights from Iowa to South Carolina

Our best United Airlines deals on Iowa to South Carolina flight tickets

United Airlines

May 13

DSM11:40 amDes Moines

4h 31m

1 stop

CLT5:11 pmCharlotte Douglas

May 16

CLT8:05 amCharlotte Douglas

7h 19m

1 stop

DSM2:24 pmDes Moines

$260

United Airlines

May 13

DSM6:15 amDes Moines

6h 53m

2 stops

CLT2:08 pmCharlotte Douglas

May 16

CLT8:05 amCharlotte Douglas

7h 19m

1 stop

DSM2:24 pmDes Moines

$266

United Airlines

Jul 15

CID7:54 amCedar Rapids

5h 12m

1 stop

CHS2:06 pmCharleston

Jul 20

CHS3:08 pmCharleston

7h 23m

1 stop

CID9:31 pmCedar Rapids

$269

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 4/20

2:04 pm-6:54 pm

1 stop27h 50m

Charlotte Douglas

Thu 4/23

6:18 pm-1:09 pm

1 stop19h 51m

$162

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 4/17

2:04 pm-4:56 pm

1 stop25h 52m

Charlotte Douglas

Sun 4/19

6:18 pm-1:09 pm

1 stop19h 51m

$192

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 4/27

8:03 pm-8:06 am

1 stop11h 03m

Charlotte Douglas

Tue 4/28

11:22 am-12:52 pm

Nonstop2h 30m

$249

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 5/13

11:40 am-5:11 pm

1 stop4h 31m

Charlotte Douglas

Sat 5/16

8:05 am-2:24 pm

1 stop7h 19m

$260

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 5/13

6:15 am-2:08 pm

2 stops6h 53m

Charlotte Douglas

Sat 5/16

8:05 am-2:24 pm

1 stop7h 19m

$266

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

Wed 4/15

3:35 pm-8:55 pm

1 stop4h 20m

Charlotte Douglas

Wed 4/22

6:20 pm-10:20 pm

1 stop5h 00m

$268

Cedar RapidsMyrtle Beach

CID - MYR

CIDMYR

Cedar Rapids

Sat 4/4

4:48 pm-10:50 pm

1 stop5h 02m

Myrtle Beach Intl

Thu 4/9

4:52 pm-11:58 pm

1 stop8h 06m

$269

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

Wed 4/15

3:35 pm-8:55 pm

1 stop4h 20m

Charlotte Douglas

Wed 4/22

7:35 am-3:40 pm

2 stops9h 05m

$273

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Sun 8/23

5:45 am-11:20 am

1 stop4h 35m

Savannah/Hilton Head

Tue 9/15

11:00 am-9:50 pm

2 stops11h 50m

$281

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Wed 6/24

5:45 am-11:24 am

1 stop4h 39m

Charleston

Tue 6/30

4:30 pm-9:50 pm

1 stop6h 20m

$294

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Iowa is in September. Flight prices, which tend to average around $285, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Iowa during January instead. Flights to South Carolina in January, while not as cheap as those in September, still average around $310.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $392 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Iowa for as low as $263 on momondo.

Can stopping save me money on Iowa to South Carolina flights?

You could potentially save up to 12% on your flight if you consider stops on a Iowa to South Carolina flight.

Cheap Iowa to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to South Carolina

Fastest flight time	2h 17m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Iowa to South Carolina takes 2h 17m

Direct flights go from Iowa to South Carolina every day.

There are 57 airports in South Carolina. From Iowa there are direct flights to Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from Iowa to South Carolina?
Prices for flights from Iowa to South Carolina are updated daily.
How many operators does momondo search for flights from Iowa to South Carolina?
As of February 2026, there are 4 operators available to choose from for flights from Iowa to South Carolina.
How old do you have to be to fly from Iowa to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Iowa to South Carolina

Compare and see reviews for airlines that fly from Iowa to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $166	Free Cancellation	Rating 7.9 8,245 reviews	Search Delta flights
United Airlines	PriceFrom $227	Free Cancellation	Rating 7.4 9,363 reviews	Search United Airlines flights
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.1 11,367 reviews	Search American Airlines flights
Southwest	PriceFrom $272	Free Cancellation	Rating 8.0 4,303 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Iowa to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Iowa to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Iowa to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Iowa to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Iowa.

I’m not ready to book a flight from Iowa to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Iowa to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.