What is the cheapest airline that flies from Iowa to South Carolina?

Frontier, United Airlines, and Delta are the most popular carriers operating from Iowa to South Carolina

What airlines fly to South Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to South Carolina from Iowa according to our data. American Airlines is the first choice among our users, with 68% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How long is the flight from Iowa to South Carolina?

Flight times vary depending on what airport in Iowa you fly out of and what airport in South Carolina you fly into. For example, flying from Cedar Rapids to Charleston takes 4h 07m on average. On the other hand, flying from Des Moines to Charleston takes 4h 18m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

How many flights depart from Iowa to South Carolina on average per week?

54 flights are operational weekly from Iowa to South Carolina as of April 2026. The most popular departure day for this route is Mon, with 17% of flights per week taking off on this day.

When did momondo last update prices for flights from Iowa to South Carolina?

Prices for flights from Iowa to South Carolina are updated daily.

How many operators does momondo search for flights from Iowa to South Carolina?

As of April 2026, there are 4 operators available to choose from for flights from Iowa to South Carolina.

How old do you have to be to fly from Iowa to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$78 Cheap Flights from Iowa to South Carolina in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Iowa to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:45 pm - 2:11 pm

CID

CLT

18h 26m

1 stop

9:07 pm - 5:55 pm

CLT

CID

21h 48m

1 stop

$164Multiple Airlines

Mon, May 4 - Thu, May 7

6:45 pm - 2:11 pm

CID

CLT

18h 26m

1 stop

9:07 pm - 5:55 pm

CLT

CID

21h 48m

1 stop

$179Multiple Airlines

Mon, May 4 - Thu, May 7

6:00 am - 12:28 pm

CID

SAV

5h 28m

1 stop

7:00 am - 11:50 am

SAV

CID

5h 50m

1 stop

$261American Airlines

Wed, Jul 15 - Tue, Jul 21

6:00 am - 12:28 pm

CID

SAV

5h 28m

1 stop

2:59 pm - 11:43 pm

SAV

CID

9h 44m

2 stops

$266American Airlines

Wed, Jul 15 - Tue, Jul 21

4:15 pm - 12:04 am

CID

SAV

6h 49m

2 stops

5:30 am - 11:27 am

SAV

CID

6h 57m

2 stops

$271Delta

Sat, Aug 22 - Sat, Aug 29

5:45 am - 1:10 pm

CID

SAV

6h 25m

1 stop

3:53 pm - 10:06 pm

SAV

CID

7h 13m

1 stop

$276Delta

Sun, May 24 - Fri, Jun 12

8:00 am - 3:39 pm

CID

SAV

6h 39m

1 stop

3:14 pm - 7:03 pm

SAV

CID

4h 49m

1 stop

$279United Airlines

Tue, May 19 - Sat, May 23

6:00 am - 2:18 pm

OMA

MYR

7h 18m

1 stop

3:14 pm - 9:38 pm

MYR

OMA

7h 24m

1 stop

$305United Airlines

Tue, May 12 - Tue, May 19

6:55 am - 6:35 pm

DSM

CHS

10h 40m

2 stops

1:15 pm - 9:15 pm

CHS

DSM

9h 00m

2 stops

$345Southwest

Tue, May 5 - Tue, May 12

10:25 am - 4:00 pm

OMA

SAV

4h 35m

1 stop

1:05 pm - 5:30 pm

SAV

OMA

5h 25m

1 stop

$354Southwest

Tue, May 5 - Sat, May 9

Frontier flights from Iowa to South Carolina

Our best Frontier deals on Iowa to South Carolina flight tickets

Frontier

May 23

OMA8:19 pmOmaha Eppley Airfield

20h 59m

1 stop

CLT6:18 pmCharlotte Douglas

May 27

CLT1:00 pmCharlotte Douglas

31h 34m

2 stops

OMA7:34 pmOmaha Eppley Airfield

$233

Frontier

May 26

OMA8:19 pmOmaha Eppley Airfield

20h 03m

2 stops

CLT5:22 pmCharlotte Douglas

May 28

CLT7:14 pmCharlotte Douglas

25h 20m

1 stop

OMA7:34 pmOmaha Eppley Airfield

$261

Frontier

Jun 1

OMA8:19 pmOmaha Eppley Airfield

20h 59m

1 stop

CLT6:18 pmCharlotte Douglas

Jun 6

CLT5:58 pmCharlotte Douglas

26h 36m

2 stops

OMA7:34 pmOmaha Eppley Airfield

$376

American Airlines flights from Iowa to South Carolina

Our best American Airlines deals on Iowa to South Carolina flight tickets

American Airlines

Jul 15

CID6:00 amCedar Rapids

5h 28m

1 stop

SAV12:28 pmSavannah/Hilton Head

Jul 21

SAV7:00 amSavannah/Hilton Head

5h 50m

1 stop

CID11:50 amCedar Rapids

$261

American Airlines

Jul 15

CID6:00 amCedar Rapids

5h 28m

1 stop

SAV12:28 pmSavannah/Hilton Head

Jul 21

SAV2:59 pmSavannah/Hilton Head

9h 44m

2 stops

CID11:43 pmCedar Rapids

$266

American Airlines

Jul 11

CID6:00 amCedar Rapids

4h 46m

1 stop

SAV11:46 amSavannah/Hilton Head

Jul 18

SAV7:00 amSavannah/Hilton Head

5h 50m

1 stop

CID11:50 amCedar Rapids

$291

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Cedar RapidsCharlotte

CID - CLT

CIDCLT

Cedar Rapids

Mon 5/4

6:45 pm-2:11 pm

1 stop18h 26m

Charlotte Douglas

Thu 5/7

9:07 pm-5:55 pm

1 stop21h 48m

$164

Cedar RapidsCharlotte

CID - CLT

CIDCLT

Cedar Rapids

Mon 5/4

6:45 pm-2:11 pm

1 stop18h 26m

Charlotte Douglas

Thu 5/7

9:07 pm-5:55 pm

1 stop21h 48m

$179

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Wed 7/15

6:00 am-12:28 pm

1 stop5h 28m

Savannah/Hilton Head

Tue 7/21

7:00 am-11:50 am

1 stop5h 50m

$261

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Wed 7/15

6:00 am-12:28 pm

1 stop5h 28m

Savannah/Hilton Head

Tue 7/21

2:59 pm-11:43 pm

2 stops9h 44m

$266

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Sat 8/22

4:15 pm-12:04 am

2 stops6h 49m

Savannah/Hilton Head

Sat 8/29

5:30 am-11:27 am

2 stops6h 57m

$271

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Sun 5/24

5:45 am-1:10 pm

1 stop6h 25m

Savannah/Hilton Head

Fri 6/12

3:53 pm-10:06 pm

1 stop7h 13m

$276

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Tue 5/19

8:00 am-3:39 pm

1 stop6h 39m

Savannah/Hilton Head

Sat 5/23

3:14 pm-7:03 pm

1 stop4h 49m

$279

OmahaMyrtle Beach

OMA - MYR

OMAMYR

Omaha Eppley Airfield

Tue 5/12

6:00 am-2:18 pm

1 stop7h 18m

Myrtle Beach Intl

Tue 5/19

3:14 pm-9:38 pm

1 stop7h 24m

$305

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Tue 5/5

6:55 am-6:35 pm

2 stops10h 40m

Charleston

Tue 5/12

1:15 pm-9:15 pm

2 stops9h 00m

$345

Quickest round-trip

OmahaSavannah

OMA - SAV

OMASAV

Omaha Eppley Airfield

Tue 5/5

10:25 am-4:00 pm

1 stop4h 35m

Savannah/Hilton Head

Sat 5/9

1:05 pm-5:30 pm

1 stop5h 25m

$354

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Iowa is in September. Flight prices, which tend to average around $280, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Iowa during January instead. Flights to South Carolina in January, while not as cheap as those in September, still average around $310.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $398 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Iowa for as low as $274 on momondo.

Can stopping save me money on Iowa to South Carolina flights?

You could potentially save up to 17% on your flight if you consider stops on a Iowa to South Carolina flight.

Cheap Iowa to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to South Carolina

Fastest flight time	2h 11m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Iowa to South Carolina takes 2h 11m

Direct flights go from Iowa to South Carolina every day.

There are 57 airports in South Carolina. From Iowa there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Iowa to South Carolina

When did momondo last update prices for flights from Iowa to South Carolina?
Prices for flights from Iowa to South Carolina are updated daily.
How many operators does momondo search for flights from Iowa to South Carolina?
As of April 2026, there are 4 operators available to choose from for flights from Iowa to South Carolina.
How old do you have to be to fly from Iowa to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Iowa to South Carolina

Compare and see reviews for airlines that fly from Iowa to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $236	Free Cancellation	Rating 7.9 8,406 reviews	Search Delta flights
American Airlines	PriceFrom $242	Free Cancellation	Rating 7.1 11,573 reviews	Search American Airlines flights
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,581 reviews	Search United Airlines flights
Southwest	PriceFrom $272	Free Cancellation	Rating 8.0 4,328 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Iowa to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Iowa to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Iowa to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Iowa to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Iowa.

I’m not ready to book a flight from Iowa to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Iowa to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.