How many flights depart from Iowa to South Carolina on average per week?

24 flights are operational weekly from Iowa to South Carolina as of April 2025. The most popular departure day for this route is Mon, with 33% of flights per week taking off on this day.

How long is the flight from Iowa to South Carolina?

Flight times vary depending on what airport in Iowa you fly out of and what airport in South Carolina you fly into. For example, flying from Des Moines to Charleston takes 4h 09m on average. On the other hand, flying from Cedar Rapids to Charleston takes 4h 45m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

What is the cheapest airline that flies from Iowa to South Carolina?

Delta, Frontier, and American Airlines are the most popular carriers operating from Iowa to South Carolina

What airlines fly to South Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to South Carolina from Iowa according to our data. American Airlines is the first choice among our users, with 70% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Iowa to South Carolina?

Prices for flights from Iowa to South Carolina are updated daily.

How many operators does momondo search for flights from Iowa to South Carolina?

As of April 2025, there are 4 operators available to choose from for flights from Iowa to South Carolina.

How old do you have to be to fly from Iowa to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$121 Cheap Flights from Iowa to South Carolina in 2025

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Find the cheapest flights from Iowa to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

These are some of the best round-trip flight deals from Iowa to South Carolina that have been recently found on momondo from popular airlines, departing in the coming months.

2:40 pm - 9:33 pmCID-CHS

5h 53m1 stop

3:51 pm - 9:26 pmCHS-CID

6h 35m1 stop

$199United Airlines

Find Deal

Tue, Jul 1 - Fri, Jul 4

6:37 am - 2:25 pmCID-CHS

6h 48m2 stops

3:51 pm - 9:26 pmCHS-CID

6h 35m1 stop

$204United Airlines

Find Deal

Tue, Jul 1 - Fri, Jul 4

7:05 am - 2:08 pmCID-CHS

6h 03m1 stop

6:16 pm - 10:53 pmCHS-CID

5h 37m1 stop

$237Delta

Find Deal

Tue, Jul 1 - Fri, Jul 4

5:56 am - 1:56 pmCID-CHS

7h 00m1 stop

7:10 am - 3:36 pmCHS-CID

9h 26m2 stops

$242Delta

Find Deal

Tue, Jul 1 - Fri, Jul 4

7:15 am - 12:54 pmCID-CHS

4h 39m1 stop

6:02 pm - 11:46 pmCHS-CID

6h 44m1 stop

$249American Airlines

Find Deal

Thu, Jul 3 - Mon, Jul 7

1:35 pm - 10:38 pmCID-SAV

8h 03m1 stop

8:15 pm - 11:57 pmSAV-CID

4h 42m1 stop

$249American Airlines

Find Deal

Wed, Jun 11 - Wed, Jun 18

12:32 pm - 3:37 pmDSM-CLT

26h 05m1 stop

11:23 am - 9:37 pmCLT-DSM

11h 14m2 stops

$250

Find Deal

Sun, May 18 - Fri, May 23

12:32 pm - 3:37 pmDSM-CLT

26h 05m1 stop

4:32 pm - 9:37 pmCLT-DSM

6h 05m1 stop

$258

Find Deal

Sun, May 18 - Fri, May 23

5:25 am - 1:55 pmOMA-CLT

7h 30m2 stops

6:30 am - 10:00 amCLT-OMA

4h 30m1 stop

$302Southwest

Find Deal

Wed, Jul 30 - Wed, Aug 6

2:30 pm - 11:15 pmOMA-CLT

7h 45m1 stop

7:30 pm - 11:35 pmCLT-OMA

5h 05m1 stop

$316Southwest

Find Deal

Sat, Jun 7 - Wed, Jun 11

Southwest flights from Iowa to South Carolina

Our best Southwest deals on Iowa to South Carolina flight tickets

Southwest

Jul 30

OMA5:25 amOmaha Eppley Airfield

7h 30m

2 stops

CLT1:55 pmCharlotte Douglas

Aug 6

CLT6:30 amCharlotte Douglas

4h 30m

1 stop

OMA10:00 amOmaha Eppley Airfield

$302

Find similar

Southwest

Jun 7

OMA2:30 pmOmaha Eppley Airfield

7h 45m

1 stop

CLT11:15 pmCharlotte Douglas

Jun 11

CLT7:30 pmCharlotte Douglas

5h 05m

1 stop

OMA11:35 pmOmaha Eppley Airfield

$316

Find similar

Southwest

Aug 20

DSM8:25 amDes Moines

8h 35m

1 stop

CLT6:00 pmCharlotte Douglas

Aug 25

CLT7:50 pmCharlotte Douglas

4h 00m

1 stop

DSM10:50 pmDes Moines

$321

Find similar

American Airlines flights from Iowa to South Carolina

Our best American Airlines deals on Iowa to South Carolina flight tickets

American Airlines

Jul 3

CID7:15 amCedar Rapids

4h 39m

1 stop

CHS12:54 pmCharleston

Jul 7

CHS6:02 pmCharleston

6h 44m

1 stop

CID11:46 pmCedar Rapids

$249

Find similar

American Airlines

Jul 4

CID5:13 amCedar Rapids

8h 36m

2 stops

CHS2:49 pmCharleston

Jul 8

CHS6:00 amCharleston

7h 04m

1 stop

CID12:04 pmCedar Rapids

$254

Find similar

American Airlines

May 30

CID11:30 amCedar Rapids

7h 28m

2 stops

CHS7:58 pmCharleston

Jun 2

CHS6:09 pmCharleston

6h 35m

2 stops

CID11:44 pmCedar Rapids

$259

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How to get the cheapest flight ticket from Iowa to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Iowa is in September. Flight prices, which tend to average around $344, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Iowa during August instead. Flights to South Carolina in August, while not as cheap as those in September, still average around $358.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Monday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $379. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $508.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Iowa to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $386. Try not to purchase tickets in the morning because they tend to be around $405. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Iowa when booking 10 weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $397 when searching 10 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Iowa for as low as $322 on momondo.

Cheap Iowa to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to South Carolina

Best Price Found	$121
Fastest flight time	2h 08m
Direct flights	Every day
Airports in South Carolina	4 airports

The best one-way flight to South Carolina from Iowa in the past 72 hours is $121. The best round-trip flight deal from Iowa to South Carolina found on momondo in the last 72 hours is $199.

The fastest flight from Iowa to South Carolina takes 2h 08m

Direct flights go from Iowa to South Carolina every day.

There are 4 airports near South Carolina: Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS)

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When did momondo last update prices for flights from Iowa to South Carolina?
Prices for flights from Iowa to South Carolina are updated daily.
How many operators does momondo search for flights from Iowa to South Carolina?
As of April 2025, there are 4 operators available to choose from for flights from Iowa to South Carolina.
How old do you have to be to fly from Iowa to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Iowa to South Carolina

Compare and see reviews for airlines that fly from Iowa to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $198	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $227	Free Cancellation	Rating 7.4 8,696 reviews	Search United Airlines flights
Delta	PriceFrom $232	Free Cancellation	Rating 8.0 7,936 reviews	Search Delta flights
Southwest	PriceFrom $376	Free Cancellation	Rating 8.0 4,294 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Iowa to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Iowa to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Iowa to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Iowa to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Iowa.

I’m not ready to book a flight from Iowa to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Iowa to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.