What is the cheapest airline that flies from Iowa to Knoxville McGhee Tyson?

Allegiant Air, American Airlines, and Frontier are the most popular carriers operating from Iowa to Knoxville McGhee Tyson

How long does it take to fly to Knoxville?

Average flight duration from Iowa to Knoxville depends on which airport you fly into and out of. Flying from Des Moines to Knoxville is 3h 52m on average, while flying from Cedar Rapids to Knoxville is 4h 20m on average. Knoxville is the most popular airport in Knoxville.

What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Iowa according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Iowa to Knoxville McGhee Tyson Airport?

Prices for flights from Iowa to Knoxville McGhee Tyson Airport are updated daily.

How many operators does momondo search for flights from Iowa to Knoxville McGhee Tyson Airport?

As of August 2025, there are 3 operators available to choose from for flights from Iowa to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Iowa to Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$118 Cheap Flights from Iowa to Knoxville in 2025

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Find the cheapest flights from Iowa to Knoxville

Round-trip

One-way

Last minute

Cheap round-trip flights

7:40 pm - 7:45 pmOMA-TYS

23h 05m1 stop

8:40 pm - 7:50 pmTYS-OMA

24h 10m1 stop

$225Frontier

Find Deal

Sun, Sep 7 - Thu, Sep 11

2:51 pm - 8:25 amDSM-TYS

16h 34m1 stop

9:00 am - 2:01 pmTYS-DSM

6h 01m1 stop

$231Allegiant Air

Find Deal

Sun, Nov 2 - Thu, Nov 6

6:30 pm - 11:44 pmDSM-TYS

4h 14m1 stop

5:45 am - 10:40 amTYS-DSM

5h 55m1 stop

$249Delta

Find Deal

Mon, Sep 15 - Sat, Sep 20

12:40 pm - 8:36 pmOMA-TYS

6h 56m1 stop

5:44 am - 9:46 amTYS-OMA

5h 02m1 stop

$249Delta

Find Deal

Tue, Oct 14 - Wed, Oct 22

5:40 pm - 12:21 amMLI-TYS

5h 41m1 stop

5:19 pm - 10:25 pmTYS-MLI

6h 06m1 stop

$249American Airlines

Find Deal

Fri, Sep 19 - Mon, Sep 22

11:38 am - 4:19 pmCID-TYS

3h 41m1 stop

7:45 pm - 10:56 pmTYS-CID

4h 11m1 stop

$249American Airlines

Find Deal

Fri, Sep 5 - Mon, Sep 8

8:00 am - 8:56 pmOMA-TYS

11h 56m2 stops

7:00 am - 10:24 amTYS-OMA

4h 24m1 stop

$254United Airlines

Find Deal

Sat, Sep 6 - Thu, Sep 11

1:49 pm - 10:30 pmOMA-TYS

7h 41m1 stop

7:00 am - 10:24 amTYS-OMA

4h 24m1 stop

$259United Airlines

Find Deal

Wed, Aug 20 - Sat, Aug 23

8:47 pm - 6:27 pmDSM-TYS

20h 40m2 stops

9:00 am - 2:01 pmTYS-DSM

6h 01m1 stop

$270

Find Deal

Sun, Nov 2 - Thu, Nov 6

11:25 am - 8:36 pmDSM-TYS

8h 11m1 stop

3:20 pm - 10:01 amTYS-DSM

19h 41m2 stops

$315

Find Deal

Mon, Oct 6 - Wed, Oct 8

Frontier flights from Iowa to Knoxville

Our best Frontier deals on Iowa to Knoxville flight tickets

Frontier

Sep 7

OMA7:40 pmOmaha Eppley Airfield

23h 05m

1 stop

TYS7:45 pmKnoxville McGhee Tyson

Sep 11

TYS8:40 pmKnoxville McGhee Tyson

24h 10m

1 stop

OMA7:50 pmOmaha Eppley Airfield

$225

Find similar

Frontier

Sep 14

OMA7:40 pmOmaha Eppley Airfield

23h 05m

1 stop

TYS7:45 pmKnoxville McGhee Tyson

Sep 18

TYS8:40 pmKnoxville McGhee Tyson

24h 10m

1 stop

OMA7:50 pmOmaha Eppley Airfield

$234

Find similar

Frontier

Aug 31

CID8:22 pmCedar Rapids

21h 03m

1 stop

TYS6:25 pmKnoxville McGhee Tyson

Sep 7

TYS5:08 pmKnoxville McGhee Tyson

27h 23m

1 stop

CID7:31 pmCedar Rapids

$255

Find similar

American Airlines flights from Iowa to Knoxville

Our best American Airlines deals on Iowa to Knoxville flight tickets

American Airlines

Sep 5

CID11:38 amCedar Rapids

3h 41m

1 stop

TYS4:19 pmKnoxville McGhee Tyson

Sep 8

TYS7:45 pmKnoxville McGhee Tyson

4h 11m

1 stop

CID10:56 pmCedar Rapids

$249

Find similar

American Airlines

Sep 5

CID1:32 pmCedar Rapids

8h 31m

2 stops

TYS11:03 pmKnoxville McGhee Tyson

Sep 8

TYS5:19 pmKnoxville McGhee Tyson

6h 37m

1 stop

CID10:56 pmCedar Rapids

$254

Find similar

American Airlines

Aug 20

CID6:01 pmCedar Rapids

5h 18m

1 stop

TYS12:19 amKnoxville McGhee Tyson

Aug 24

TYS8:25 pmKnoxville McGhee Tyson

4h 34m

1 stop

CID11:59 pmCedar Rapids

$259

Find similar

Fly from

Fly to

Route

Depart

Return

Price

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Sun 9/7

7:40 pm-7:45 pm

1 stop23h 05m

Knoxville McGhee Tyson

Thu 9/11

8:40 pm-7:50 pm

1 stop24h 10m

$225

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sun 11/2

2:51 pm-8:25 am

1 stop16h 34m

Knoxville McGhee Tyson

Thu 11/6

9:00 am-2:01 pm

1 stop6h 01m

$231

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Mon 9/15

6:30 pm-11:44 pm

1 stop4h 14m

Knoxville McGhee Tyson

Sat 9/20

5:45 am-10:40 am

1 stop5h 55m

$249

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Tue 10/14

12:40 pm-8:36 pm

1 stop6h 56m

Knoxville McGhee Tyson

Wed 10/22

5:44 am-9:46 am

1 stop5h 02m

$249

MolineKnoxville

MLI - TYS

MLITYS

Moline Quad-City

Fri 9/19

5:40 pm-12:21 am

1 stop5h 41m

Knoxville McGhee Tyson

Mon 9/22

5:19 pm-10:25 pm

1 stop6h 06m

$249

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Fri 9/5

11:38 am-4:19 pm

1 stop3h 41m

Knoxville McGhee Tyson

Mon 9/8

7:45 pm-10:56 pm

1 stop4h 11m

$249

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Sat 9/6

8:00 am-8:56 pm

2 stops11h 56m

Knoxville McGhee Tyson

Thu 9/11

7:00 am-10:24 am

1 stop4h 24m

$254

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Wed 8/20

1:49 pm-10:30 pm

1 stop7h 41m

Knoxville McGhee Tyson

Sat 8/23

7:00 am-10:24 am

1 stop4h 24m

$259

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sun 11/2

8:47 pm-6:27 pm

2 stops20h 40m

Knoxville McGhee Tyson

Thu 11/6

9:00 am-2:01 pm

1 stop6h 01m

$270

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Mon 10/6

11:25 am-8:36 pm

1 stop8h 11m

Knoxville McGhee Tyson

Wed 10/8

3:20 pm-10:01 am

2 stops19h 41m

$315

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Iowa, with most prices found around $253. If you aren’t able to travel during the month of January, then book flights to Knoxville from Iowa during July instead. Flights to Knoxville in July, while not as cheap as those in January, still average around $313.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Iowa to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $283. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Iowa to Knoxville for around $456.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Iowa to Knoxville when you can find flight prices for as low as $322. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $368.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $358 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Iowa for as low as $252 on momondo.

Can stopping save me money on Iowa to Knoxville flights?

You could potentially save up to 70% on your flight if you consider stops on a Iowa to Knoxville flight.

Cheap Iowa to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Knoxville

Best Price Found	$118
Fastest flight time	3h 41m
Direct flights	None
Airports in Knoxville	1 airport

The best one-way flight to Knoxville from Iowa in the past 72 hours is $118. The best round-trip flight deal from Iowa to Knoxville found on momondo in the last 72 hours is $225.

The fastest flight from Iowa to Knoxville takes 3h 41m

There are no direct flights from Iowa to Knoxville. Popular non-direct routes for this connection are Omaha Eppley Airfield Airport - Knoxville McGhee Tyson Airport, Des Moines Airport - Knoxville McGhee Tyson Airport and Moline Quad-City Airport - Knoxville McGhee Tyson Airport.

There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

Search flight deals

When did momondo last update prices for flights from Iowa to Knoxville McGhee Tyson Airport?
Prices for flights from Iowa to Knoxville McGhee Tyson Airport are updated daily.
How many operators does momondo search for flights from Iowa to Knoxville McGhee Tyson Airport?
As of August 2025, there are 3 operators available to choose from for flights from Iowa to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Iowa to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Knoxville

Compare and see reviews for airlines that fly from Iowa to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $219	Free Cancellation	Rating 8.0 7,985 reviews	Search Delta flights
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 8,917 reviews	Search United Airlines flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Crossville

Maryville

Murphy

Newport

Alcoa

Lenoir City

Oak Ridge

Kodak

Dandridge

Clinton

Jefferson City

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Knoxville?

It is quick and easy to find Iowa to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Iowa to Knoxville with flexible booking policies on momondo?

All flight searches from Iowa to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to Knoxville?

Once you have performed a search for Iowa to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Iowa to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Iowa to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.