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Cheap flights from Houston to Knoxville from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Knoxville departing on 3/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Houston to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:30 am - 10:07 pm
IAH
-
TYS
14h 37m
1 stop
Multiple Airlines Logo
2:06 pm - 11:11 am
TYS
-
IAH
22h 05m
1 stop
$188Multiple Airlines
Thu, Feb 26 - Mon, Mar 2
Multiple Airlines Logo
6:30 am - 10:10 pm
IAH
-
TYS
14h 40m
1 stop
Multiple Airlines Logo
5:56 pm - 10:44 pm
TYS
-
IAH
29h 48m
1 stop
$194Multiple Airlines
Thu, Feb 19 - Sun, Feb 22
American Airlines Logo
6:00 am - 12:30 pm
IAH
-
TYS
5h 30m
1 stop
American Airlines Logo
6:54 pm - 11:59 pm
TYS
-
IAH
6h 05m
1 stop
$197American Airlines
Wed, Apr 29 - Sat, May 2
Frontier Logo
6:39 am - 7:27 pm
IAH
-
TYS
11h 48m
1 stop
Frontier Logo
8:13 pm - 11:32 pm
TYS
-
IAH
28h 19m
1 stop
$204Frontier
Fri, Feb 20 - Mon, Feb 23
Delta Logo
5:25 am - 11:08 am
HOU
-
TYS
4h 43m
1 stop
Delta Logo
5:35 am - 10:01 am
TYS
-
HOU
5h 26m
1 stop
$205Delta
Wed, Feb 18 - Wed, Feb 25
Delta Logo
9:54 am - 3:15 pm
IAH
-
TYS
4h 21m
1 stop
Delta Logo
5:35 am - 9:33 am
TYS
-
IAH
4h 58m
1 stop
$205Delta
Wed, Feb 18 - Sat, Feb 21
Multiple Airlines Logo
6:30 am - 10:10 pm
IAH
-
TYS
14h 40m
1 stop
Multiple Airlines Logo
5:56 pm - 10:41 pm
TYS
-
IAH
29h 45m
2 stops
$223Multiple Airlines
Thu, Feb 19 - Sun, Feb 22
American Airlines Logo
6:00 am - 11:31 am
IAH
-
TYS
4h 31m
1 stop
American Airlines Logo
4:29 pm - 8:21 pm
TYS
-
IAH
4h 52m
1 stop
$229American Airlines
Thu, Feb 26 - Mon, Mar 2
Southwest Logo
7:00 am - 2:10 pm
HOU
-
TYS
6h 10m
1 stop
Southwest Logo
2:55 pm - 8:20 pm
TYS
-
HOU
6h 25m
1 stop
$333Southwest
Fri, Apr 17 - Tue, Apr 21
Southwest Logo
12:30 pm - 8:20 pm
HOU
-
TYS
6h 50m
2 stops
Southwest Logo
2:55 pm - 6:50 pm
TYS
-
HOU
4h 55m
1 stop
$338Southwest
Fri, Apr 17 - Tue, Apr 21

Delta flights from Houston to Knoxville

Our best Delta deals on Houston to Knoxville flight tickets
Delta
Feb 18
HOU5:25 amHouston Hobby
4h 43m
1 stop
TYS11:08 amKnoxville McGhee Tyson
Feb 20
TYS6:41 pmKnoxville McGhee Tyson
4h 47m
1 stop
HOU10:28 pmHouston Hobby
$205
Delta
Feb 18
HOU5:25 amHouston Hobby
4h 43m
1 stop
TYS11:08 amKnoxville McGhee Tyson
Feb 25
TYS5:35 amKnoxville McGhee Tyson
5h 26m
1 stop
HOU10:01 amHouston Hobby
$249
Delta
Apr 9
IAH9:51 amHouston George Bush Intcntl
6h 54m
1 stop
TYS5:45 pmKnoxville McGhee Tyson
Apr 11
TYS5:40 amKnoxville McGhee Tyson
5h 37m
1 stop
IAH10:17 amHouston George Bush Intcntl
$254

American Airlines flights from Houston to Knoxville

Our best American Airlines deals on Houston to Knoxville flight tickets
American Airlines
Apr 29
IAH6:00 amHouston George Bush Intcntl
5h 30m
1 stop
TYS12:30 pmKnoxville McGhee Tyson
May 2
TYS6:54 pmKnoxville McGhee Tyson
6h 05m
1 stop
IAH11:59 pmHouston George Bush Intcntl
$197
American Airlines
Feb 26
IAH6:00 amHouston George Bush Intcntl
4h 31m
1 stop
TYS11:31 amKnoxville McGhee Tyson
Mar 2
TYS4:29 pmKnoxville McGhee Tyson
4h 52m
1 stop
IAH8:21 pmHouston George Bush Intcntl
$229
American Airlines
Apr 2
HOU6:00 amHouston Hobby
4h 30m
1 stop
TYS11:30 amKnoxville McGhee Tyson
Apr 5
TYS5:40 amKnoxville McGhee Tyson
7h 08m
1 stop
HOU11:48 amHouston Hobby
$268

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Houston to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Thu 2/26

6:30 am-10:07 pm

1 stop14h 37m

Knoxville McGhee Tyson

Mon 3/2

2:06 pm-11:11 am

1 stop22h 05m

$188

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Thu 2/19

6:30 am-10:10 pm

1 stop14h 40m

Knoxville McGhee Tyson

Sun 2/22

5:56 pm-10:44 pm

1 stop29h 48m

$194

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Wed 4/29

6:00 am-12:30 pm

1 stop5h 30m

Knoxville McGhee Tyson

Sat 5/2

6:54 pm-11:59 pm

1 stop6h 05m

$197

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Fri 2/20

6:39 am-7:27 pm

1 stop11h 48m

Knoxville McGhee Tyson

Mon 2/23

8:13 pm-11:32 pm

1 stop28h 19m

$204

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Wed 2/18

5:25 am-11:08 am

1 stop4h 43m

Knoxville McGhee Tyson

Wed 2/25

5:35 am-10:01 am

1 stop5h 26m

$205

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Wed 2/18

9:54 am-3:15 pm

1 stop4h 21m

Knoxville McGhee Tyson

Sat 2/21

5:35 am-9:33 am

1 stop4h 58m

$205

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Thu 2/19

6:30 am-10:10 pm

1 stop14h 40m

Knoxville McGhee Tyson

Sun 2/22

5:56 pm-10:41 pm

2 stops29h 45m

$223

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Thu 2/26

6:00 am-11:31 am

1 stop4h 31m

Knoxville McGhee Tyson

Mon 3/2

4:29 pm-8:21 pm

1 stop4h 52m

$229

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Fri 4/17

7:00 am-2:10 pm

1 stop6h 10m

Knoxville McGhee Tyson

Tue 4/21

2:55 pm-8:20 pm

1 stop6h 25m

$333

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Fri 4/17

12:30 pm-8:20 pm

2 stops6h 50m

Knoxville McGhee Tyson

Tue 4/21

2:55 pm-6:50 pm

1 stop4h 55m

$338

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Houston to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Houston, with most prices found around $248. If you aren’t able to travel during the month of August, then book flights to Knoxville from Houston during June instead. Flights to Knoxville in June, while not as cheap as those in August, still average around $258.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Houston to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $88. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Houston to Knoxville for around $399.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Houston to Knoxville when you can find flight prices for as low as $246. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $420.

What is the cheapest Houston to Knoxville McGhee Tyson flight route?

Fly from Houston George Bush Intcntl to Knoxville McGhee Tyson for the best Houston - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $296 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Houston for as low as $224 on momondo.

What cabin class options are available on Houston to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Houston to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Knoxville

Fastest flight time

2h 03m

Direct flights

Every day

Airports in Knoxville

1 airport
The fastest flight from Houston to Knoxville takes 2h 03m
Direct flights go from Houston to Knoxville every day.
There is 1 airport in Knoxville. From Houston there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

  • How far is Houston to Knoxville McGhee Tyson by plane?

    There are 789.2 mi between Houston and Knoxville McGhee Tyson. Typically, this will take 2h 03m by plane in normal conditions.

  • When did momondo last update prices for flights from Houston to Knoxville McGhee Tyson Airport?

    Prices for flights from Houston to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Houston to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Houston to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Houston to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Knoxville

Compare and see reviews for airlines that fly from Houston to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $54Free CancellationRating
7.2
709 reviews
Search Allegiant Air flights
DeltaPriceFrom $104Free CancellationRating
7.9
8,146 reviews
Search Delta flights
United AirlinesPriceFrom $209Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights
American AirlinesPriceFrom $228Free CancellationRating
7.2
11,222 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Knoxville?

It is quick and easy to find Houston to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Houston to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Houston to Knoxville.

I’m not ready to book a flight from Houston to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Houston. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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