What airlines fly to Des Moines?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Des Moines from Harrisburg according to our data. Delta is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Harrisburg to Des Moines?

Frontier, Allegiant Air, and Delta are the most popular carriers operating from Harrisburg to Des Moines

When did momondo last update prices for flights from Harrisburg Airport to Des Moines Airport?

Prices for flights from Harrisburg Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Harrisburg Airport to Des Moines Airport?

There are 3 operators available for flights from Harrisburg Airport to Des Moines Airport as of January 2026.

How old do you have to be to fly from Harrisburg Airport to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$255 Cheap Flights from Harrisburg to Des Moines in 2026

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Find the cheapest flights from Harrisburg to Des Moines

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:13 pm - 9:30 am

MDT

DSM

12h 17m

1 stop

10:40 am - 5:52 pm

DSM

MDT

6h 12m

1 stop

$259Frontier

Thu, Mar 12 - Tue, Mar 17

6:31 pm - 11:40 pm

MDT

DSM

6h 09m

1 stop

5:00 am - 12:01 pm

DSM

MDT

6h 01m

1 stop

$269American Airlines

Thu, Feb 26 - Tue, Mar 3

6:31 pm - 11:40 pm

MDT

DSM

6h 09m

1 stop

5:00 am - 12:01 pm

DSM

MDT

6h 01m

1 stop

$274American Airlines

Fri, Feb 13 - Tue, Feb 17

6:31 pm - 11:40 pm

MDT

DSM

6h 09m

1 stop

1:48 pm - 10:59 pm

DSM

MDT

8h 11m

2 stops

$279American Airlines

Fri, Feb 13 - Tue, Feb 17

6:31 pm - 11:40 pm

MDT

DSM

6h 09m

1 stop

1:48 pm - 10:59 pm

DSM

MDT

8h 11m

2 stops

$284American Airlines

Fri, Feb 13 - Tue, Feb 17

6:30 am - 10:21 am

MDT

DSM

4h 51m

1 stop

11:22 am - 4:54 pm

DSM

MDT

4h 32m

1 stop

$297United Airlines

Thu, May 28 - Sat, May 30

4:54 pm - 9:06 pm

MDT

DSM

5h 12m

1 stop

5:00 pm - 11:50 pm

DSM

MDT

5h 50m

1 stop

$303American Airlines

Sat, Apr 11 - Thu, Apr 30

6:15 am - 2:24 pm

MDT

DSM

9h 09m

2 stops

3:28 pm - 11:13 pm

DSM

MDT

6h 45m

2 stops

$319United Airlines

Thu, Mar 12 - Tue, Mar 17

6:00 am - 11:28 am

MDT

DSM

6h 28m

1 stop

5:00 pm - 11:50 pm

DSM

MDT

5h 50m

1 stop

$339American Airlines

Thu, Apr 9 - Thu, Apr 30

8:29 am - 12:29 pm

MDT

DSM

5h 00m

1 stop

11:28 am - 12:22 am

DSM

MDT

11h 54m

2 stops

$344United Airlines

Thu, Apr 9 - Wed, Apr 29

United Airlines flights from Harrisburg to Des Moines

Our best United Airlines deals on Harrisburg to Des Moines flight tickets

United Airlines

May 28

MDT6:30 amHarrisburg

4h 51m

1 stop

DSM10:21 amDes Moines

May 30

DSM11:22 amDes Moines

4h 32m

1 stop

MDT4:54 pmHarrisburg

$297

United Airlines

Mar 12

MDT6:15 amHarrisburg

9h 09m

2 stops

DSM2:24 pmDes Moines

Mar 17

DSM3:28 pmDes Moines

6h 45m

2 stops

MDT11:13 pmHarrisburg

$319

United Airlines

Apr 9

MDT8:29 amHarrisburg

5h 00m

1 stop

DSM12:29 pmDes Moines

Apr 29

DSM11:28 amDes Moines

11h 54m

2 stops

MDT12:22 amHarrisburg

$344

American Airlines flights from Harrisburg to Des Moines

Our best American Airlines deals on Harrisburg to Des Moines flight tickets

American Airlines

Feb 26

MDT6:31 pmHarrisburg

6h 09m

1 stop

DSM11:40 pmDes Moines

Mar 3

DSM5:00 amDes Moines

6h 01m

1 stop

MDT12:01 pmHarrisburg

$269

American Airlines

Feb 13

MDT6:31 pmHarrisburg

6h 09m

1 stop

DSM11:40 pmDes Moines

Feb 17

DSM5:00 amDes Moines

6h 01m

1 stop

MDT12:01 pmHarrisburg

$274

American Airlines

Feb 13

MDT6:31 pmHarrisburg

6h 09m

1 stop

DSM11:40 pmDes Moines

Feb 17

DSM1:48 pmDes Moines

8h 11m

2 stops

MDT10:59 pmHarrisburg

$279

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 3/12

10:13 pm-9:30 am

1 stop12h 17m

Des Moines

Tue 3/17

10:40 am-5:52 pm

1 stop6h 12m

$259

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 2/26

6:31 pm-11:40 pm

1 stop6h 09m

Des Moines

Tue 3/3

5:00 am-12:01 pm

1 stop6h 01m

$269

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 2/13

6:31 pm-11:40 pm

1 stop6h 09m

Des Moines

Tue 2/17

5:00 am-12:01 pm

1 stop6h 01m

$274

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 2/13

6:31 pm-11:40 pm

1 stop6h 09m

Des Moines

Tue 2/17

1:48 pm-10:59 pm

2 stops8h 11m

$279

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 2/13

6:31 pm-11:40 pm

1 stop6h 09m

Des Moines

Tue 2/17

1:48 pm-10:59 pm

2 stops8h 11m

$284

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 5/28

6:30 am-10:21 am

1 stop4h 51m

Des Moines

Sat 5/30

11:22 am-4:54 pm

1 stop4h 32m

$297

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 4/11

4:54 pm-9:06 pm

1 stop5h 12m

Des Moines

Thu 4/30

5:00 pm-11:50 pm

1 stop5h 50m

$303

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 3/12

6:15 am-2:24 pm

2 stops9h 09m

Des Moines

Tue 3/17

3:28 pm-11:13 pm

2 stops6h 45m

$319

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 4/9

6:00 am-11:28 am

1 stop6h 28m

Des Moines

Thu 4/30

5:00 pm-11:50 pm

1 stop5h 50m

$339

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 4/9

8:29 am-12:29 pm

1 stop5h 00m

Des Moines

Wed 4/29

11:28 am-12:22 am

2 stops11h 54m

$344

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Harrisburg to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in April, then September is your next best option. Flight prices from Harrisburg to Des Moines during September average around $278.

When to book flights from Harrisburg to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Harrisburg to Des Moines (MDT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Des Moines

Fastest flight time	4h 22m
Direct flights	None

The fastest flight from Harrisburg to Des Moines takes 4h 22m

There are no direct flights from Harrisburg to Des Moines. There are no popular flight routes from Harrisburg to Des Moines.

Search flight deals

How far is Harrisburg to Des Moines by plane?
Harrisburg and Des Moines are 876.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 22m.
When did momondo last update prices for flights from Harrisburg Airport to Des Moines Airport?
Prices for flights from Harrisburg Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Harrisburg Airport to Des Moines Airport?
There are 3 operators available for flights from Harrisburg Airport to Des Moines Airport as of January 2026.
How old do you have to be to fly from Harrisburg Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Harrisburg to Des Moines?
Based on momondo bookings for flights between Harrisburg and Des Moines, the leading airline is United Airlines, making up 35% of the total bookings. Other popular airlines include American Airlines with 34% and Delta with 30%.

Best airlines flying from Harrisburg to Des Moines

Compare and see reviews for airlines that fly from Harrisburg to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,205 reviews	Search American Airlines flights
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,215 reviews	Search United Airlines flights
Delta	PriceFrom $278	Free Cancellation	Rating 7.9 8,128 reviews	Search Delta flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Pella

Newton

Johnston

Boone

Osceola

Norwalk

Oskaloosa

Grinnell

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Des Moines?

Finding the right flight to Des Moines from Harrisburg is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Harrisburg to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Harrisburg on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Harrisburg to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Harrisburg.

I’m not ready to book a flight from Harrisburg to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from Harrisburg. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.