What is the cheapest airline that flies from Harrisburg to Des Moines?

United Airlines is the most popular carrier operating from Harrisburg to Des Moines

What airlines fly to Des Moines?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Des Moines from Harrisburg according to our data. Delta is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Harrisburg Airport to Des Moines Airport?

Prices for flights from Harrisburg Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Harrisburg Airport to Des Moines Airport?

There are 3 operators available for flights from Harrisburg Airport to Des Moines Airport as of August 2025.

How old do you have to be to fly from Harrisburg Airport to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$222 Cheap Flights from Harrisburg to Des Moines in 2025

Q: What is the typical price of a round-trip flight between Harrisburg and Des Moines?

Prices are currently low for flights on this route. Typical prices usually range from $306 to $672. The lowest price recently found on this route was $279.

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Find the cheapest flights from Harrisburg to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

3:30 pm - 8:11 pmMDT-DSM

5h 41m1 stop

5:00 am - 10:57 amDSM-MDT

4h 57m1 stop

$279American Airlines

Find Deal

Fri, Oct 17 - Sun, Oct 19

2:24 pm - 11:41 pmMDT-DSM

10h 17m2 stops

11:35 am - 4:54 pmDSM-MDT

4h 19m1 stop

$374United Airlines

Find Deal

Tue, Sep 2 - Sat, Sep 6

6:00 am - 10:05 amMDT-DSM

5h 05m1 stop

5:56 pm - 11:00 pmDSM-MDT

4h 04m1 stop

$388Delta

Find Deal

Thu, Oct 16 - Sun, Oct 19

8:21 pm - 8:30 amMDT-DSM

13h 09m1 stop

10:41 am - 5:12 pmDSM-MDT

29h 31m2 stops

$411

Find Deal

Thu, Oct 16 - Sun, Oct 19

2:24 pm - 9:45 pmMDT-DSM

8h 21m2 stops

6:00 am - 4:54 pmDSM-MDT

9h 54m2 stops

$419United Airlines

Find Deal

Tue, Sep 2 - Sat, Sep 6

12:35 pm - 4:51 pmMDT-DSM

5h 16m1 stop

6:20 am - 11:57 amDSM-MDT

4h 37m1 stop

$447Delta

Find Deal

Mon, Nov 10 - Thu, Nov 13

8:10 pm - 11:44 pmMDT-DSM

4h 34m1 stop

12:55 pm - 10:04 pmDSM-MDT

8h 09m2 stops

$452American Airlines

Find Deal

Mon, Nov 10 - Thu, Nov 13

12:33 pm - 10:30 pmMDT-DSM

10h 57m2 stops

2:13 pm - 11:08 pmDSM-MDT

7h 55m1 stop

$463Delta

Find Deal

Thu, Oct 30 - Sun, Nov 2

5:48 pm - 9:50 pmMDT-DSM

5h 02m1 stop

6:36 pm - 9:29 amDSM-MDT

13h 53m2 stops

$559United Airlines

Find Deal

Fri, Oct 17 - Sun, Oct 19

8:15 am - 12:14 pmMDT-DSM

4h 59m1 stop

11:26 am - 9:35 amDSM-MDT

21h 09m3 stops

$596United Airlines

Find Deal

Thu, Oct 30 - Sun, Nov 2

United Airlines flights from Harrisburg to Des Moines

Our best United Airlines deals on Harrisburg to Des Moines flight tickets

United Airlines

Sep 2

MDT2:24 pmHarrisburg

10h 17m

2 stops

DSM11:41 pmDes Moines

Sep 6

DSM11:35 amDes Moines

4h 19m

1 stop

MDT4:54 pmHarrisburg

$374

Find similar

United Airlines

Sep 2

MDT2:24 pmHarrisburg

8h 21m

2 stops

DSM9:45 pmDes Moines

Sep 6

DSM6:00 amDes Moines

9h 54m

2 stops

MDT4:54 pmHarrisburg

$419

Find similar

United Airlines

Aug 29

MDT2:24 pmHarrisburg

8h 21m

2 stops

DSM9:45 pmDes Moines

Sep 2

DSM8:00 amDes Moines

9h 58m

2 stops

MDT6:58 pmHarrisburg

$430

Find similar

Delta flights from Harrisburg to Des Moines

Our best Delta deals on Harrisburg to Des Moines flight tickets

Delta

Aug 28

MDT6:10 amHarrisburg

4h 27m

1 stop

DSM9:37 amDes Moines

Sep 1

DSM5:55 pmDes Moines

4h 24m

1 stop

MDT11:19 pmHarrisburg

$284

Find similar

Delta

Oct 16

MDT6:00 amHarrisburg

5h 05m

1 stop

DSM10:05 amDes Moines

Oct 19

DSM5:56 pmDes Moines

4h 04m

1 stop

MDT11:00 pmHarrisburg

$388

Find similar

Delta

Aug 21

MDT12:28 pmHarrisburg

5h 17m

1 stop

DSM4:45 pmDes Moines

Aug 25

DSM11:23 amDes Moines

10h 56m

2 stops

MDT11:19 pmHarrisburg

$409

Find similar

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 10/17

3:30 pm-8:11 pm

1 stop5h 41m

Des Moines

Sun 10/19

5:00 am-10:57 am

1 stop4h 57m

$279

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 9/2

2:24 pm-11:41 pm

2 stops10h 17m

Des Moines

Sat 9/6

11:35 am-4:54 pm

1 stop4h 19m

$374

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 10/16

6:00 am-10:05 am

1 stop5h 05m

Des Moines

Sun 10/19

5:56 pm-11:00 pm

1 stop4h 04m

$388

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 10/16

8:21 pm-8:30 am

1 stop13h 09m

Des Moines

Sun 10/19

10:41 am-5:12 pm

2 stops29h 31m

$411

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 9/2

2:24 pm-9:45 pm

2 stops8h 21m

Des Moines

Sat 9/6

6:00 am-4:54 pm

2 stops9h 54m

$419

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Mon 11/10

12:35 pm-4:51 pm

1 stop5h 16m

Des Moines

Thu 11/13

6:20 am-11:57 am

1 stop4h 37m

$447

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Mon 11/10

8:10 pm-11:44 pm

1 stop4h 34m

Des Moines

Thu 11/13

12:55 pm-10:04 pm

2 stops8h 09m

$452

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 10/30

12:33 pm-10:30 pm

2 stops10h 57m

Des Moines

Sun 11/2

2:13 pm-11:08 pm

1 stop7h 55m

$463

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 10/17

5:48 pm-9:50 pm

1 stop5h 02m

Des Moines

Sun 10/19

6:36 pm-9:29 am

2 stops13h 53m

$559

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 10/30

8:15 am-12:14 pm

1 stop4h 59m

Des Moines

Sun 11/2

11:26 am-9:35 am

3 stops21h 09m

$596

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first

How to get the cheapest flight ticket from Harrisburg to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Harrisburg and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in April, then October is your next best option. Flight prices from Harrisburg to Des Moines during October average around $328.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Harrisburg to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $311. Flights from Harrisburg to Des Moines on a Sunday will generally be more expensive and average around $802. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Harrisburg to Des Moines in the afternoon for as low as $374. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $437. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Harrisburg to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Harrisburg to Des Moines (MDT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Des Moines

Direct flights	None

There are no direct flights from Harrisburg to Des Moines. There are no popular flight routes from Harrisburg to Des Moines.

Search flight deals

How far is Harrisburg to Des Moines by plane?
Harrisburg and Des Moines are 876.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 34m.
When did momondo last update prices for flights from Harrisburg Airport to Des Moines Airport?
Prices for flights from Harrisburg Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Harrisburg Airport to Des Moines Airport?
There are 3 operators available for flights from Harrisburg Airport to Des Moines Airport as of August 2025.
How old do you have to be to fly from Harrisburg Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Harrisburg to Des Moines?
Based on momondo bookings for flights between Harrisburg and Des Moines, the leading airline is American Airlines, making up 42% of the total bookings. Other popular airlines include United Airlines with 32% and Delta with 27%.

Best airlines flying from Harrisburg to Des Moines

Compare and see reviews for airlines that fly from Harrisburg to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 8,928 reviews	Search United Airlines flights
American Airlines	PriceFrom $253	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $278	Free Cancellation	Rating 7.9 7,982 reviews	Search Delta flights

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Newton

Pella

Osceola

Johnston

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Des Moines?

Finding the right flight to Des Moines from Harrisburg is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Harrisburg to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Harrisburg on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Harrisburg to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Harrisburg.

I’m not ready to book a flight from Harrisburg to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from Harrisburg. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Harrisburg to Des Moines from $279

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to Des Moines departing on 10/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from Harrisburg to Des Moines

Cheap round-trip flights

Cheap one-way flights

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United Airlines flights from Harrisburg to Des Moines

Our best United Airlines deals on Harrisburg to Des Moines flight tickets

Delta flights from Harrisburg to Des Moines

Our best Delta deals on Harrisburg to Des Moines flight tickets

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Use the filters below to find and compare flights from Harrisburg to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from Harrisburg to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Harrisburg and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in April, then October is your next best option. Flight prices from Harrisburg to Des Moines during October average around $328.

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest airline that flies from Harrisburg to Des Moines?

United Airlines is the most popular carrier operating from Harrisburg to Des Moines

What airlines fly to Des Moines?

When to book flights from Harrisburg to Des Moines

Cheap Harrisburg to Des Moines (MDT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Des Moines

Direct flights

How far is Harrisburg to Des Moines by plane?

When did momondo last update prices for flights from Harrisburg Airport to Des Moines Airport?

How many operators does momondo search for flights from Harrisburg Airport to Des Moines Airport?

How old do you have to be to fly from Harrisburg Airport to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular airline from Harrisburg to Des Moines?

Best airlines flying from Harrisburg to Des Moines

Compare and see reviews for airlines that fly from Harrisburg to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Des Moines?

Can I find flights from Harrisburg to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from Harrisburg to Des Moines?

I’m not ready to book a flight from Harrisburg to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa