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Cheap flights from Harrisburg to Des Moines from $269

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to Des Moines departing on 9/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Harrisburg to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:43 pm - 12:09 am
MDT
-
DSM
7h 26m
1 stop
American Airlines Logo
6:33 pm - 12:22 am
DSM
-
MDT
4h 49m
1 stop
$309American Airlines
Thu, Jul 9 - Mon, Jul 20
Allegiant Air Logo
10:20 am - 5:04 pm
MDT
-
DSM
7h 44m
1 stop
Allegiant Air Logo
3:59 pm - 4:52 pm
DSM
-
MDT
23h 53m
1 stop
$312Allegiant Air
Thu, Jul 16 - Sun, Jul 19
American Airlines Logo
7:08 pm - 12:35 am
MDT
-
DSM
6h 27m
1 stop
American Airlines Logo
6:02 am - 2:00 pm
DSM
-
MDT
6h 58m
1 stop
$319American Airlines
Mon, Jun 15 - Sat, Jun 20
American Airlines Logo
7:08 pm - 12:35 am
MDT
-
DSM
6h 27m
1 stop
American Airlines Logo
1:37 pm - 10:24 pm
DSM
-
MDT
7h 47m
2 stops
$324American Airlines
Tue, Jun 23 - Tue, Jun 30
United Airlines Logo
2:17 pm - 6:14 pm
MDT
-
DSM
4h 57m
1 stop
United Airlines Logo
11:23 am - 7:47 pm
DSM
-
MDT
7h 24m
1 stop
$339United Airlines
Sat, May 23 - Wed, May 27
United Airlines Logo
2:52 pm - 11:44 pm
MDT
-
DSM
9h 52m
2 stops
United Airlines Logo
6:50 pm - 12:27 am
DSM
-
MDT
4h 37m
1 stop
$344United Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
6:00 am - 1:18 pm
MDT
-
DSM
8h 18m
2 stops
American Airlines Logo
1:48 pm - 10:12 pm
DSM
-
MDT
7h 24m
2 stops
$349American Airlines
Sat, May 23 - Wed, May 27
Allegiant Air Logo
7:59 pm - 8:33 am
MDT
-
DSM
13h 34m
1 stop
Allegiant Air Logo
3:52 pm - 9:35 am
DSM
-
MDT
16h 43m
1 stop
$352Allegiant Air
Sat, Jul 25 - Fri, Jul 31
Delta Logo
6:04 am - 10:43 am
MDT
-
DSM
5h 39m
1 stop
Delta Logo
4:47 pm - 11:55 pm
DSM
-
MDT
6h 08m
1 stop
$364Delta
Mon, Jun 15 - Sat, Jun 20
Allegiant Air Logo
10:20 am - 5:19 pm
MDT
-
DSM
7h 59m
1 stop
Allegiant Air Logo
4:01 pm - 4:50 pm
DSM
-
MDT
23h 49m
1 stop
$379Allegiant Air
Thu, Jun 4 - Sun, Jun 7

American Airlines flights from Harrisburg to Des Moines

Our best American Airlines deals on Harrisburg to Des Moines flight tickets
American Airlines
Jun 15
MDT7:08 pmHarrisburg
6h 27m
1 stop
DSM12:35 amDes Moines
Jun 20
DSM6:02 amDes Moines
6h 58m
1 stop
MDT2:00 pmHarrisburg
$319
American Airlines
Jun 23
MDT7:08 pmHarrisburg
6h 27m
1 stop
DSM12:35 amDes Moines
Jun 30
DSM1:37 pmDes Moines
7h 47m
2 stops
MDT10:24 pmHarrisburg
$324
American Airlines
May 23
MDT6:00 amHarrisburg
8h 18m
2 stops
DSM1:18 pmDes Moines
May 27
DSM1:48 pmDes Moines
7h 24m
2 stops
MDT10:12 pmHarrisburg
$349

United Airlines flights from Harrisburg to Des Moines

Our best United Airlines deals on Harrisburg to Des Moines flight tickets
United Airlines
May 23
MDT2:17 pmHarrisburg
4h 57m
1 stop
DSM6:14 pmDes Moines
May 27
DSM11:23 amDes Moines
7h 24m
1 stop
MDT7:47 pmHarrisburg
$339
United Airlines
May 23
MDT2:52 pmHarrisburg
9h 52m
2 stops
DSM11:44 pmDes Moines
May 27
DSM6:50 pmDes Moines
4h 37m
1 stop
MDT12:27 amHarrisburg
$344
United Airlines
Sep 2
MDT5:53 pmHarrisburg
4h 19m
1 stop
DSM9:12 pmDes Moines
Sep 5
DSM11:23 amDes Moines
4h 28m
1 stop
MDT4:51 pmHarrisburg
$389

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Harrisburg to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 7/9

5:43 pm-12:09 am

1 stop7h 26m

Des Moines

Mon 7/20

6:33 pm-12:22 am

1 stop4h 49m

$309

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 7/16

10:20 am-5:04 pm

1 stop7h 44m

Des Moines

Sun 7/19

3:59 pm-4:52 pm

1 stop23h 53m

$312

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Mon 6/15

7:08 pm-12:35 am

1 stop6h 27m

Des Moines

Sat 6/20

6:02 am-2:00 pm

1 stop6h 58m

$319

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 6/23

7:08 pm-12:35 am

1 stop6h 27m

Des Moines

Tue 6/30

1:37 pm-10:24 pm

2 stops7h 47m

$324

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 5/23

2:17 pm-6:14 pm

1 stop4h 57m

Des Moines

Wed 5/27

11:23 am-7:47 pm

1 stop7h 24m

$339

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 5/23

2:52 pm-11:44 pm

2 stops9h 52m

Des Moines

Wed 5/27

6:50 pm-12:27 am

1 stop4h 37m

$344

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 5/23

6:00 am-1:18 pm

2 stops8h 18m

Des Moines

Wed 5/27

1:48 pm-10:12 pm

2 stops7h 24m

$349

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 7/25

7:59 pm-8:33 am

1 stop13h 34m

Des Moines

Fri 7/31

3:52 pm-9:35 am

1 stop16h 43m

$352
Quickest round-trip

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Mon 6/15

6:04 am-10:43 am

1 stop5h 39m

Des Moines

Sat 6/20

4:47 pm-11:55 pm

1 stop6h 08m

$364

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 6/4

10:20 am-5:19 pm

1 stop7h 59m

Des Moines

Sun 6/7

4:01 pm-4:50 pm

1 stop23h 49m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Harrisburg to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Harrisburg and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then October is your next best option. Flight prices from Harrisburg to Des Moines during October average around $313.

When to book flights from Harrisburg to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Harrisburg to Des Moines (MDT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Des Moines

Fastest flight time

4h 07m

Direct flights

None
The fastest flight from Harrisburg to Des Moines takes 4h 07m
There are no direct flights from Harrisburg to Des Moines. There are no popular flight routes from Harrisburg to Des Moines.
Search flight deals

Frequently asked questions about flying from Harrisburg to Des Moines

  • How far is Harrisburg to Des Moines by plane?

    Harrisburg and Des Moines are 876.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 07m.

  • When did momondo last update prices for flights from Harrisburg Airport to Des Moines Airport?

    Prices for flights from Harrisburg Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Harrisburg Airport to Des Moines Airport?

  • How old do you have to be to fly from Harrisburg Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Harrisburg to Des Moines?

Best airlines flying from Harrisburg to Des Moines

Compare and see reviews for airlines that fly from Harrisburg to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,694 reviews
Search United Airlines flights
DeltaPriceFrom $268Free CancellationRating
7.9
8,454 reviews
Search Delta flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Des Moines?

Finding the right flight to Des Moines from Harrisburg is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Harrisburg to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Harrisburg on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Harrisburg to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Harrisburg.

I’m not ready to book a flight from Harrisburg to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from Harrisburg. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Des Moines trip

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