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Cheap flights from Harrisburg to Des Moines from $309

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to Des Moines departing on 7/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Harrisburg to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:45 pm - 12:01 am
MDT
-
DSM
5h 16m
1 stop
American Airlines Logo
6:33 pm - 12:22 am
DSM
-
MDT
4h 49m
1 stop
$309American Airlines
Wed, Jul 29 - Mon, Aug 3
United Airlines Logo
5:54 pm - 9:27 pm
MDT
-
DSM
4h 33m
1 stop
United Airlines Logo
3:11 pm - 11:29 pm
DSM
-
MDT
7h 18m
2 stops
$314United Airlines
Wed, Sep 23 - Sat, Oct 10
American Airlines Logo
7:45 pm - 12:01 am
MDT
-
DSM
5h 16m
1 stop
American Airlines Logo
1:35 pm - 7:05 pm
DSM
-
MDT
4h 30m
1 stop
$324American Airlines
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
7:45 pm - 12:01 am
MDT
-
DSM
5h 16m
1 stop
American Airlines Logo
1:35 pm - 10:10 pm
DSM
-
MDT
7h 35m
2 stops
$329American Airlines
Tue, Jul 14 - Tue, Jul 21
United Airlines Logo
5:55 pm - 9:22 pm
MDT
-
DSM
4h 27m
1 stop
United Airlines Logo
6:00 am - 2:03 pm
DSM
-
MDT
7h 03m
2 stops
$338United Airlines
Fri, Aug 7 - Sat, Aug 15
United Airlines Logo
5:55 pm - 10:56 pm
MDT
-
DSM
6h 01m
1 stop
United Airlines Logo
6:00 am - 2:00 pm
DSM
-
MDT
7h 00m
2 stops
$343United Airlines
Tue, Aug 4 - Sat, Aug 8
American Airlines Logo
7:31 pm - 12:20 am
MDT
-
DSM
5h 49m
1 stop
American Airlines Logo
1:55 pm - 11:03 pm
DSM
-
MDT
8h 08m
2 stops
$348American Airlines
Thu, Aug 13 - Sat, Aug 22
American Airlines Logo
7:45 pm - 12:01 am
MDT
-
DSM
5h 16m
1 stop
American Airlines Logo
1:35 pm - 7:05 pm
DSM
-
MDT
4h 30m
1 stop
$369American Airlines
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
7:45 pm - 12:01 am
MDT
-
DSM
5h 16m
1 stop
American Airlines Logo
1:35 pm - 10:10 pm
DSM
-
MDT
7h 35m
2 stops
$374American Airlines
Tue, Jul 14 - Tue, Jul 21
United Airlines Logo
6:30 am - 10:31 am
MDT
-
DSM
5h 01m
1 stop
United Airlines Logo
3:11 pm - 9:50 pm
DSM
-
MDT
5h 39m
1 stop
$381United Airlines
Thu, Oct 8 - Sun, Oct 11

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American Airlines flights from Harrisburg to Des Moines

Our best American Airlines deals on Harrisburg to Des Moines flight tickets
American Airlines
Jul 29
MDT7:45 pmHarrisburg
5h 16m
1 stop
DSM12:01 amDes Moines
Aug 3
DSM6:33 pmDes Moines
4h 49m
1 stop
MDT12:22 amHarrisburg
$309
American Airlines
Jul 14
MDT7:45 pmHarrisburg
5h 16m
1 stop
DSM12:01 amDes Moines
Jul 21
DSM1:35 pmDes Moines
4h 30m
1 stop
MDT7:05 pmHarrisburg
$324
American Airlines
Jul 14
MDT7:45 pmHarrisburg
5h 16m
1 stop
DSM12:01 amDes Moines
Jul 21
DSM1:35 pmDes Moines
7h 35m
2 stops
MDT10:10 pmHarrisburg
$329

Allegiant Air flights from Harrisburg to Des Moines

Our best Allegiant Air deals on Harrisburg to Des Moines flight tickets
Allegiant Air
Jul 29
MDT2:10 pmHarrisburg
19h 23m
1 stop
DSM8:33 amDes Moines
Aug 3
DSM5:30 pmDes Moines
16h 59m
2 stops
MDT11:29 amHarrisburg
$445
Allegiant Air
Jul 30
MDT5:58 pmHarrisburg
22h 52m
1 stop
DSM3:50 pmDes Moines
Aug 3
DSM5:30 pmDes Moines
16h 59m
2 stops
MDT11:29 amHarrisburg
$449
Allegiant Air
Jul 29
MDT2:10 pmHarrisburg
19h 23m
1 stop
DSM8:33 amDes Moines
Aug 2
DSM10:57 amDes Moines
21h 28m
2 stops
MDT9:25 amHarrisburg
$489

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Harrisburg to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Wed 7/29

7:45 pm-12:01 am

1 stop5h 16m

Des Moines

Mon 8/3

6:33 pm-12:22 am

1 stop4h 49m

$309

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Wed 9/23

5:54 pm-9:27 pm

1 stop4h 33m

Des Moines

Sat 10/10

3:11 pm-11:29 pm

2 stops7h 18m

$314
Quickest round-trip

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 7/14

7:45 pm-12:01 am

1 stop5h 16m

Des Moines

Tue 7/21

1:35 pm-7:05 pm

1 stop4h 30m

$324

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 7/14

7:45 pm-12:01 am

1 stop5h 16m

Des Moines

Tue 7/21

1:35 pm-10:10 pm

2 stops7h 35m

$329

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 8/7

5:55 pm-9:22 pm

1 stop4h 27m

Des Moines

Sat 8/15

6:00 am-2:03 pm

2 stops7h 03m

$338

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 8/4

5:55 pm-10:56 pm

1 stop6h 01m

Des Moines

Sat 8/8

6:00 am-2:00 pm

2 stops7h 00m

$343

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 8/13

7:31 pm-12:20 am

1 stop5h 49m

Des Moines

Sat 8/22

1:55 pm-11:03 pm

2 stops8h 08m

$348

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 7/14

7:45 pm-12:01 am

1 stop5h 16m

Des Moines

Tue 7/21

1:35 pm-7:05 pm

1 stop4h 30m

$369

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 7/14

7:45 pm-12:01 am

1 stop5h 16m

Des Moines

Tue 7/21

1:35 pm-10:10 pm

2 stops7h 35m

$374

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 10/8

6:30 am-10:31 am

1 stop5h 01m

Des Moines

Sun 10/11

3:11 pm-9:50 pm

1 stop5h 39m

$381

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Des Moines from

How to get the cheapest flight ticket from Harrisburg to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Harrisburg and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then August is your next best option. Flight prices from Harrisburg to Des Moines during August average around $308.

When to book flights from Harrisburg to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Harrisburg to Des Moines (MDT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Des Moines

Fastest flight time

4h 25m

Direct flights

None
The fastest flight from Harrisburg to Des Moines takes 4h 25m
There are no direct flights from Harrisburg to Des Moines. There are no popular flight routes from Harrisburg to Des Moines.
Search flight deals

Frequently asked questions about flying from Harrisburg to Des Moines

  • How far is Harrisburg to Des Moines by plane?

    Harrisburg and Des Moines are 876.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 25m.

  • When did momondo last update prices for flights from Harrisburg Airport to Des Moines Airport?

    Prices for flights from Harrisburg Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Harrisburg Airport to Des Moines Airport?

  • How old do you have to be to fly from Harrisburg Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Harrisburg to Des Moines?

Best airlines flying from Harrisburg to Des Moines

Compare and see reviews for airlines that fly from Harrisburg to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,770 reviews
Search American Airlines flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,926 reviews
Search United Airlines flights
DeltaPriceFrom $268Free CancellationRating
7.8
8,452 reviews
Search Delta flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Des Moines?

Finding the right flight to Des Moines from Harrisburg is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Harrisburg to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Harrisburg on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Harrisburg to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Harrisburg.

I’m not ready to book a flight from Harrisburg to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from Harrisburg. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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