Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Guayaquil to Knoxville from $374

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guayaquil to Knoxville departing on 8/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Guayaquil to Knoxville

Cheap round-trip flights

United Airlines Logo
12:15 pm - 7:52 pmGYE-TYS
30h 37m2 stops
United Airlines Logo
7:00 am - 11:41 pmTYS-GYE
16h 41m2 stops
$647United Airlines
Find Deal
lun., oct. 20 - lun., nov. 10
American Airlines Logo
8:15 am - 11:35 pmGYE-TYS
14h 20m1 stop
American Airlines Logo
7:20 pm - 10:40 pmTYS-GYE
27h 20m2 stops
$708American Airlines
Find Deal
lun., oct. 20 - lun., nov. 10
American Airlines Logo
8:15 am - 9:52 amGYE-TYS
24h 37m2 stops
American Airlines Logo
5:07 pm - 10:40 pmTYS-GYE
29h 33m1 stop
$733American Airlines
Find Deal
lun., oct. 20 - lun., nov. 10
American Airlines Logo
8:15 am - 11:29 amGYE-TYS
26h 14m2 stops
American Airlines Logo
5:07 pm - 10:40 pmTYS-GYE
29h 33m1 stop
$735American Airlines
Find Deal
lun., oct. 20 - lun., nov. 10
Logo
11:05 am - 8:02 pmGYE-TYS
31h 57m2 stops
Logo
7:25 pm - 2:05 amTYS-GYE
31h 40m2 stops
$755
Find Deal
mié., ago. 13 - mar., ago. 26
American Airlines Logo
8:15 am - 11:35 pmGYE-TYS
14h 20m1 stop
American Airlines Logo
5:07 pm - 10:40 pmTYS-GYE
29h 33m1 stop
$756American Airlines
Find Deal
lun., oct. 20 - lun., nov. 10
American Airlines Logo
8:15 am - 11:35 pmGYE-TYS
14h 20m1 stop
American Airlines Logo
5:07 pm - 10:40 pmTYS-GYE
29h 33m1 stop
$757American Airlines
Find Deal
lun., oct. 20 - lun., nov. 10
United Airlines Logo
12:17 pm - 6:11 pmGYE-TYS
28h 54m2 stops
United Airlines Logo
7:20 am - 1:46 pmTYS-GYE
31h 26m2 stops
$1,031United Airlines
Find Deal
lun., ago. 11 - mar., ago. 26
Avianca Logo
3:15 am - 10:27 amGYE-TYS
30h 12m2 stops
Avianca Logo
7:25 pm - 2:05 amTYS-GYE
31h 40m2 stops
$1,256Avianca
Find Deal
lun., ago. 11 - mar., ago. 26
Avianca Logo
3:15 am - 8:57 pmGYE-TYS
16h 42m2 stops
Avianca Logo
7:25 pm - 2:05 amTYS-GYE
31h 40m2 stops
$1,335Avianca
Find Deal
mar., ago. 12 - mar., ago. 26

American Airlines flights from Guayaquil to Knoxville

Our best American Airlines deals on Guayaquil to Knoxville flight tickets
American Airlines
Oct 20
GYE8:15 amGuayaquil Jose Joaquin de Olmedo
14h 20m
1 stop
TYS11:35 pmKnoxville McGhee Tyson
Nov 10
TYS7:20 pmKnoxville McGhee Tyson
27h 20m
2 stops
GYE10:40 pmGuayaquil Jose Joaquin de Olmedo
$708
Find similar
American Airlines
Oct 20
GYE8:15 amGuayaquil Jose Joaquin de Olmedo
24h 37m
2 stops
TYS9:52 amKnoxville McGhee Tyson
Nov 10
TYS5:07 pmKnoxville McGhee Tyson
29h 33m
1 stop
GYE10:40 pmGuayaquil Jose Joaquin de Olmedo
$733
Find similar
American Airlines
Oct 20
GYE8:15 amGuayaquil Jose Joaquin de Olmedo
26h 14m
2 stops
TYS11:29 amKnoxville McGhee Tyson
Nov 10
TYS5:07 pmKnoxville McGhee Tyson
29h 33m
1 stop
GYE10:40 pmGuayaquil Jose Joaquin de Olmedo
$735
Find similar

Avianca flights from Guayaquil to Knoxville

Our best Avianca deals on Guayaquil to Knoxville flight tickets
Avianca
Aug 11
GYE3:15 amGuayaquil Jose Joaquin de Olmedo
30h 12m
2 stops
TYS10:27 amKnoxville McGhee Tyson
Aug 26
TYS7:25 pmKnoxville McGhee Tyson
31h 40m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
$1,256
Find similar
Avianca
Aug 12
GYE3:15 amGuayaquil Jose Joaquin de Olmedo
16h 42m
2 stops
TYS8:57 pmKnoxville McGhee Tyson
Aug 26
TYS7:25 pmKnoxville McGhee Tyson
31h 40m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
$1,335
Find similar
Avianca
Aug 10
GYE3:35 amGuayaquil Jose Joaquin de Olmedo
29h 52m
2 stops
TYS10:27 amKnoxville McGhee Tyson
Aug 26
TYS7:25 pmKnoxville McGhee Tyson
31h 40m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
$1,859
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Guayaquil to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from Guayaquil to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 10/20

12:15 pm-7:52 pm

2 stops30h 37m

Knoxville McGhee Tyson

lun. 11/10

7:00 am-11:41 pm

2 stops16h 41m

$647

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 10/20

8:15 am-11:35 pm

1 stop14h 20m

Knoxville McGhee Tyson

lun. 11/10

7:20 pm-10:40 pm

2 stops27h 20m

$708

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 10/20

8:15 am-9:52 am

2 stops24h 37m

Knoxville McGhee Tyson

lun. 11/10

5:07 pm-10:40 pm

1 stop29h 33m

$733

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 10/20

8:15 am-11:29 am

2 stops26h 14m

Knoxville McGhee Tyson

lun. 11/10

5:07 pm-10:40 pm

1 stop29h 33m

$735

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

mié. 8/13

11:05 am-8:02 pm

2 stops31h 57m

Knoxville McGhee Tyson

mar. 8/26

7:25 pm-2:05 am

2 stops31h 40m

$755

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 10/20

8:15 am-11:35 pm

1 stop14h 20m

Knoxville McGhee Tyson

lun. 11/10

5:07 pm-10:40 pm

1 stop29h 33m

$756

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 10/20

8:15 am-11:35 pm

1 stop14h 20m

Knoxville McGhee Tyson

lun. 11/10

5:07 pm-10:40 pm

1 stop29h 33m

$757

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 8/11

12:17 pm-6:11 pm

2 stops28h 54m

Knoxville McGhee Tyson

mar. 8/26

7:20 am-1:46 pm

2 stops31h 26m

$1,031

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 8/11

3:15 am-10:27 am

2 stops30h 12m

Knoxville McGhee Tyson

mar. 8/26

7:25 pm-2:05 am

2 stops31h 40m

$1,256

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

mar. 8/12

3:15 am-8:57 pm

2 stops16h 42m

Knoxville McGhee Tyson

mar. 8/26

7:25 pm-2:05 am

2 stops31h 40m

$1,335

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Guayaquil to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Guayaquil to Knoxville is on a Monday. Travelers who choose to depart for Knoxville on a Monday will often find tickets for as low as $671. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Guayaquil to Knoxville for around $777.

When to book flights from Guayaquil to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Guayaquil to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guayaquil to Knoxville (GYE to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guayaquil to Knoxville

Best Price Found

$374

Fastest flight time

14h 20m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Guayaquil in the past 72 hours is $374. The best round-trip flight deal from Guayaquil to Knoxville found on momondo in the last 72 hours is $647.
The fastest flight from Guayaquil to Knoxville takes 14h 20m
There are no direct flights from Guayaquil to Knoxville. Popular non-direct route for this connection is Guayaquil Jose Joaquin de Olmedo Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Guayaquil Jose Joaquin de Olmedo to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 2647.2 mi away from Guayaquil Jose Joaquin de Olmedo. In terms of flight time, this usually takes a little over 14h 20m.

  • When did momondo last update prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Guayaquil Jose Joaquin de Olmedo Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Guayaquil Jose Joaquin de Olmedo Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Guayaquil Jose Joaquin de Olmedo Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Guayaquil to Knoxville?

Best airlines flying from Guayaquil to Knoxville

Compare and see reviews for airlines that fly from Guayaquil to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $388Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Alcoa
Lenoir City
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Guayaquil to Knoxville?

Finding the right flight to Knoxville from Guayaquil is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Guayaquil to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Guayaquil on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Guayaquil to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Guayaquil.

I’m not ready to book a flight from Guayaquil to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Guayaquil are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
mar. 8/5
mar. 8/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States