Latest deals
When to book
FAQs
Price Alerts

Cheap flights from Greenville, North Carolina to Knoxville from $407

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville, North Carolina to Knoxville departing on 4/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Greenville, North Carolina to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:10 pm - 11:59 pm
PGV
-
TYS
3h 49m
1 stop
American Airlines Logo
5:57 pm - 11:56 pm
TYS
-
PGV
5h 59m
1 stop
$407American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
5:05 am - 8:42 am
PGV
-
TYS
3h 37m
1 stop
American Airlines Logo
5:57 pm - 11:56 pm
TYS
-
PGV
5h 59m
1 stop
$437American Airlines
Sat, Apr 4 - Wed, Apr 8
American Airlines Logo
6:03 pm - 11:50 pm
PGV
-
TYS
5h 47m
1 stop
American Airlines Logo
12:01 pm - 11:56 pm
TYS
-
PGV
11h 55m
2 stops
$556American Airlines
Sat, Apr 4 - Wed, Apr 8
American Airlines Logo
8:00 pm - 11:55 pm
PGV
-
TYS
3h 55m
1 stop
American Airlines Logo
7:00 am - 12:28 pm
TYS
-
PGV
5h 28m
1 stop
$578American Airlines
Fri, Apr 17 - Sun, Apr 19
American Airlines Logo
11:00 am - 5:16 pm
PGV
-
TYS
6h 16m
1 stop
American Airlines Logo
7:02 am - 10:35 am
TYS
-
PGV
3h 33m
1 stop
$583American Airlines
Thu, Apr 2 - Mon, Apr 6
American Airlines Logo
8:10 pm - 11:59 pm
PGV
-
TYS
3h 49m
1 stop
American Airlines Logo
12:01 pm - 11:56 pm
TYS
-
PGV
11h 55m
2 stops
$861American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
5:05 am - 3:49 pm
PGV
-
TYS
10h 44m
2 stops
American Airlines Logo
12:01 pm - 11:56 pm
TYS
-
PGV
11h 55m
2 stops
$883American Airlines
Sat, Apr 4 - Wed, Apr 8
American Airlines Logo
11:00 am - 5:16 pm
PGV
-
TYS
6h 16m
1 stop
American Airlines Logo
6:05 am - 5:35 pm
TYS
-
PGV
11h 30m
2 stops
$895American Airlines
Thu, Apr 2 - Mon, Apr 6
American Airlines Logo
5:05 am - 3:38 pm
PGV
-
TYS
10h 33m
2 stops
American Airlines Logo
7:00 am - 12:28 pm
TYS
-
PGV
5h 28m
1 stop
$932American Airlines
Fri, Apr 17 - Sun, Apr 19
American Airlines Logo
5:05 am - 3:32 pm
PGV
-
TYS
10h 27m
2 stops
American Airlines Logo
2:06 pm - 7:45 pm
TYS
-
PGV
5h 39m
1 stop
$1,006American Airlines
Sun, Apr 5 - Thu, Apr 9

American Airlines flights from Greenville, North Carolina to Knoxville

Our best American Airlines deals on Greenville, North Carolina to Knoxville flight tickets
American Airlines
Apr 9
PGV8:10 pmPitt-Greenville
3h 49m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
Apr 13
TYS5:57 pmKnoxville McGhee Tyson
5h 59m
1 stop
PGV11:56 pmPitt-Greenville
$407
American Airlines
Apr 4
PGV5:05 amPitt-Greenville
3h 37m
1 stop
TYS8:42 amKnoxville McGhee Tyson
Apr 8
TYS5:57 pmKnoxville McGhee Tyson
5h 59m
1 stop
PGV11:56 pmPitt-Greenville
$437
American Airlines
Apr 4
PGV6:03 pmPitt-Greenville
5h 47m
1 stop
TYS11:50 pmKnoxville McGhee Tyson
Apr 8
TYS12:01 pmKnoxville McGhee Tyson
11h 55m
2 stops
PGV11:56 pmPitt-Greenville
$556

momondo Fare Finder

 
Customize your flight search to find flights from Greenville, North Carolina to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Greenville, North Carolina to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Thu 4/9

8:10 pm-11:59 pm

1 stop3h 49m

Knoxville McGhee Tyson

Mon 4/13

5:57 pm-11:56 pm

1 stop5h 59m

$407

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sat 4/4

5:05 am-8:42 am

1 stop3h 37m

Knoxville McGhee Tyson

Wed 4/8

5:57 pm-11:56 pm

1 stop5h 59m

$437

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sat 4/4

6:03 pm-11:50 pm

1 stop5h 47m

Knoxville McGhee Tyson

Wed 4/8

12:01 pm-11:56 pm

2 stops11h 55m

$556
Quickest round-trip

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Fri 4/17

8:00 pm-11:55 pm

1 stop3h 55m

Knoxville McGhee Tyson

Sun 4/19

7:00 am-12:28 pm

1 stop5h 28m

$578

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Thu 4/2

11:00 am-5:16 pm

1 stop6h 16m

Knoxville McGhee Tyson

Mon 4/6

7:02 am-10:35 am

1 stop3h 33m

$583

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Thu 4/9

8:10 pm-11:59 pm

1 stop3h 49m

Knoxville McGhee Tyson

Mon 4/13

12:01 pm-11:56 pm

2 stops11h 55m

$861

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sat 4/4

5:05 am-3:49 pm

2 stops10h 44m

Knoxville McGhee Tyson

Wed 4/8

12:01 pm-11:56 pm

2 stops11h 55m

$883

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Thu 4/2

11:00 am-5:16 pm

1 stop6h 16m

Knoxville McGhee Tyson

Mon 4/6

6:05 am-5:35 pm

2 stops11h 30m

$895

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Fri 4/17

5:05 am-3:38 pm

2 stops10h 33m

Knoxville McGhee Tyson

Sun 4/19

7:00 am-12:28 pm

1 stop5h 28m

$932

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sun 4/5

5:05 am-3:32 pm

2 stops10h 27m

Knoxville McGhee Tyson

Thu 4/9

2:06 pm-7:45 pm

1 stop5h 39m

$1,006

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Greenville, North Carolina to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville, North Carolina to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville, North Carolina to Knoxville (PGV to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville, North Carolina to Knoxville

Fastest flight time

3h 49m

Direct flights

None
The fastest flight from Greenville, North Carolina to Knoxville takes 3h 49m
There are no direct flights from Greenville, North Carolina to Knoxville. There are no popular flight routes from Greenville, North Carolina to Knoxville.
Search flight deals

  • How far is Pitt-Greenville to Knoxville McGhee Tyson by plane?

    The distance between Pitt-Greenville and Knoxville McGhee Tyson is about 367.8 mi. Flights usually cover this in 3h 49m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • How do I get Price Alerts for flights from Greenville, North Carolina to Knoxville?

    Search flight deals from Greenville, North Carolina to Knoxville. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Greenville, North Carolina to Knoxville with momondo?

    Plan your trips smart with the “Price Forecast” feature, which uses flight data to help you pick the best days to fly for the lowest fares. Our “Price Calendar” helps you get the most for your money by showing you when it’s most advantageous to fly. Curate your own travel experiences for less with “Explore”. Expert travel hacks to fuel your next adventure are a click away with “Discover” by momondo. Set up our “Price Alerts” to track fare changes and book when prices are at their lowest point.

  • How does momondo find its flight prices?

    We compare prices from 700+ competitors to help you find the price that works best for you. momondo operates in over 30 international markets, bringing you access to a wide range of fares and deals. Search for your travel using momondo for a diverse range of options from airlines and OTAs.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Jefferson City
Dandridge
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Greenville to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Greenville to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Greenville to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Greenville to Knoxville?

Once you have performed a search for Greenville to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Greenville to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Greenville to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 4/22
Wed 4/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States