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Cheap flights from Greenville, North Carolina to Knoxville from $254

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville, North Carolina to Knoxville departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville, North Carolina to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:10 am - 8:34 am
PGV
-
TYS
3h 24m
1 stop
American Airlines Logo
12:51 pm - 5:38 pm
TYS
-
PGV
4h 47m
1 stop
$377American Airlines
Thu, Jun 4 - Sat, Jun 6
American Airlines Logo
5:10 am - 8:34 am
PGV
-
TYS
3h 24m
1 stop
American Airlines Logo
11:18 am - 11:58 pm
TYS
-
PGV
12h 40m
2 stops
$458American Airlines
Thu, Jun 4 - Sat, Jun 6
American Airlines Logo
6:03 pm - 9:58 pm
PGV
-
TYS
3h 55m
1 stop
American Airlines Logo
5:00 am - 10:36 am
TYS
-
PGV
5h 36m
1 stop
$472American Airlines
Mon, Jun 8 - Sun, Jun 14
American Airlines Logo
6:03 pm - 11:47 pm
PGV
-
TYS
5h 44m
1 stop
American Airlines Logo
6:07 pm - 11:58 pm
TYS
-
PGV
5h 51m
1 stop
$477American Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
5:10 am - 8:34 am
PGV
-
TYS
3h 24m
1 stop
American Airlines Logo
6:07 pm - 11:58 pm
TYS
-
PGV
5h 51m
1 stop
$487American Airlines
Sun, May 24 - Wed, Jun 3
American Airlines Logo
5:10 am - 10:36 am
PGV
-
TYS
5h 26m
1 stop
American Airlines Logo
7:59 pm - 11:58 pm
TYS
-
PGV
3h 59m
1 stop
$507American Airlines
Wed, May 27 - Mon, Jun 1
American Airlines Logo
5:10 am - 8:34 am
PGV
-
TYS
3h 24m
1 stop
American Airlines Logo
5:00 am - 10:36 am
TYS
-
PGV
5h 36m
1 stop
$517American Airlines
Sun, May 24 - Tue, Jun 2
American Airlines Logo
5:10 am - 5:03 pm
PGV
-
TYS
11h 53m
2 stops
American Airlines Logo
7:59 pm - 11:58 pm
TYS
-
PGV
3h 59m
1 stop
$522American Airlines
Sun, May 24 - Mon, Jun 1
American Airlines Logo
5:10 am - 10:36 am
PGV
-
TYS
5h 26m
1 stop
American Airlines Logo
7:59 pm - 11:58 pm
TYS
-
PGV
3h 59m
1 stop
$537American Airlines
Mon, May 25 - Wed, Jun 3
American Airlines Logo
6:03 pm - 9:58 pm
PGV
-
TYS
3h 55m
1 stop
American Airlines Logo
6:07 pm - 11:58 pm
TYS
-
PGV
5h 51m
1 stop
$547American Airlines
Sat, May 23 - Mon, Jun 1

American Airlines flights from Greenville, North Carolina to Knoxville

Our best American Airlines deals on Greenville, North Carolina to Knoxville flight tickets
American Airlines
Jun 4
PGV5:10 amPitt-Greenville
3h 24m
1 stop
TYS8:34 amKnoxville McGhee Tyson
Jun 6
TYS12:51 pmKnoxville McGhee Tyson
4h 47m
1 stop
PGV5:38 pmPitt-Greenville
$377
American Airlines
Jun 4
PGV5:10 amPitt-Greenville
3h 24m
1 stop
TYS8:34 amKnoxville McGhee Tyson
Jun 6
TYS11:18 amKnoxville McGhee Tyson
12h 40m
2 stops
PGV11:58 pmPitt-Greenville
$458
American Airlines
Jun 8
PGV6:03 pmPitt-Greenville
3h 55m
1 stop
TYS9:58 pmKnoxville McGhee Tyson
Jun 14
TYS5:00 amKnoxville McGhee Tyson
5h 36m
1 stop
PGV10:36 amPitt-Greenville
$472

momondo Fare Finder

 
Customize your flight search to find flights from Greenville, North Carolina to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Greenville, North Carolina to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Thu 6/4

5:10 am-8:34 am

1 stop3h 24m

Knoxville McGhee Tyson

Sat 6/6

12:51 pm-5:38 pm

1 stop4h 47m

$377

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Thu 6/4

5:10 am-8:34 am

1 stop3h 24m

Knoxville McGhee Tyson

Sat 6/6

11:18 am-11:58 pm

2 stops12h 40m

$458

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Mon 6/8

6:03 pm-9:58 pm

1 stop3h 55m

Knoxville McGhee Tyson

Sun 6/14

5:00 am-10:36 am

1 stop5h 36m

$472

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Wed 5/27

6:03 pm-11:47 pm

1 stop5h 44m

Knoxville McGhee Tyson

Wed 6/3

6:07 pm-11:58 pm

1 stop5h 51m

$477

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sun 5/24

5:10 am-8:34 am

1 stop3h 24m

Knoxville McGhee Tyson

Wed 6/3

6:07 pm-11:58 pm

1 stop5h 51m

$487

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Wed 5/27

5:10 am-10:36 am

1 stop5h 26m

Knoxville McGhee Tyson

Mon 6/1

7:59 pm-11:58 pm

1 stop3h 59m

$507

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sun 5/24

5:10 am-8:34 am

1 stop3h 24m

Knoxville McGhee Tyson

Tue 6/2

5:00 am-10:36 am

1 stop5h 36m

$517

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sun 5/24

5:10 am-5:03 pm

2 stops11h 53m

Knoxville McGhee Tyson

Mon 6/1

7:59 pm-11:58 pm

1 stop3h 59m

$522

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Mon 5/25

5:10 am-10:36 am

1 stop5h 26m

Knoxville McGhee Tyson

Wed 6/3

7:59 pm-11:58 pm

1 stop3h 59m

$537

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sat 5/23

6:03 pm-9:58 pm

1 stop3h 55m

Knoxville McGhee Tyson

Mon 6/1

6:07 pm-11:58 pm

1 stop5h 51m

$547

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Greenville, North Carolina to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Pitt-Greenville to Knoxville McGhee Tyson?

American Airlines is the most popular carrier operating from Pitt-Greenville to Knoxville McGhee Tyson

When to book flights from Greenville, North Carolina to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville, North Carolina to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville, North Carolina to Knoxville (PGV to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville, North Carolina to Knoxville

Fastest flight time

3h 10m

Direct flights

None
The fastest flight from Greenville, North Carolina to Knoxville takes 3h 10m
There are no direct flights from Greenville, North Carolina to Knoxville. There are no popular flight routes from Greenville, North Carolina to Knoxville.
Search flight deals

Frequently asked questions about flying from Greenville, North Carolina to Knoxville

  • How far is Pitt-Greenville to Knoxville McGhee Tyson by plane?

    The distance between Pitt-Greenville and Knoxville McGhee Tyson is about 367.8 mi. Flights usually cover this in 3h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Crossville
Maryville
Murphy
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Greenville to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Greenville to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Greenville to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Greenville to Knoxville?

Once you have performed a search for Greenville to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Greenville to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Greenville to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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