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Cheap flights from Greenville, North Carolina to Knoxville from $327

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville, North Carolina to Knoxville departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Greenville, North Carolina to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:00 am - 10:30 amPGV-TYS
5h 30m1 stop
American Airlines Logo
8:13 pm - 11:59 pmTYS-PGV
3h 46m1 stop
$327American Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
5:00 am - 3:46 pmPGV-TYS
10h 46m2 stops
American Airlines Logo
8:13 pm - 11:59 pmTYS-PGV
3h 46m1 stop
$356American Airlines
Find Deal
Sat, Dec 6 - Sun, Dec 7
American Airlines Logo
5:00 am - 3:54 pmPGV-TYS
10h 54m2 stops
American Airlines Logo
8:13 pm - 11:59 pmTYS-PGV
3h 46m1 stop
$430American Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
7:16 pm - 10:55 pmPGV-TYS
3h 39m1 stop
American Airlines Logo
5:00 am - 10:36 amTYS-PGV
5h 36m1 stop
$431American Airlines
Find Deal
Wed, Dec 17 - Wed, Dec 24
American Airlines Logo
6:00 am - 9:36 pmPGV-TYS
15h 36m2 stops
American Airlines Logo
7:00 am - 10:36 amTYS-PGV
3h 36m1 stop
$450American Airlines
Find Deal
Wed, Dec 17 - Wed, Dec 24
American Airlines Logo
3:55 pm - 9:29 pmPGV-TYS
5h 34m1 stop
American Airlines Logo
6:58 am - 10:22 amTYS-PGV
3h 24m1 stop
$452American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:12 am - 9:43 pmPGV-TYS
16h 31m2 stops
American Airlines Logo
6:58 am - 10:22 amTYS-PGV
3h 24m1 stop
$476American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
6:00 am - 9:36 pmPGV-TYS
15h 36m2 stops
American Airlines Logo
5:15 am - 5:31 pmTYS-PGV
12h 16m2 stops
$506American Airlines
Find Deal
Wed, Dec 17 - Wed, Dec 24
American Airlines Logo
5:00 am - 3:46 pmPGV-TYS
10h 46m2 stops
American Airlines Logo
6:00 am - 5:34 pmTYS-PGV
11h 34m2 stops
$562American Airlines
Find Deal
Sat, Dec 6 - Sun, Dec 7
American Airlines Logo
6:00 am - 9:50 amPGV-TYS
3h 50m1 stop
American Airlines Logo
5:51 pm - 11:59 pmTYS-PGV
6h 08m1 stop
$597American Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21

American Airlines flights from Greenville, North Carolina to Knoxville

Our best American Airlines deals on Greenville, North Carolina to Knoxville flight tickets
American Airlines
Dec 4
PGV5:00 amPitt-Greenville
5h 30m
1 stop
TYS10:30 amKnoxville McGhee Tyson
Dec 7
TYS8:13 pmKnoxville McGhee Tyson
3h 46m
1 stop
PGV11:59 pmPitt-Greenville
$327
Find similar
American Airlines
Dec 6
PGV5:00 amPitt-Greenville
10h 46m
2 stops
TYS3:46 pmKnoxville McGhee Tyson
Dec 7
TYS8:13 pmKnoxville McGhee Tyson
3h 46m
1 stop
PGV11:59 pmPitt-Greenville
$356
Find similar
American Airlines
Dec 4
PGV5:00 amPitt-Greenville
10h 54m
2 stops
TYS3:54 pmKnoxville McGhee Tyson
Dec 7
TYS8:13 pmKnoxville McGhee Tyson
3h 46m
1 stop
PGV11:59 pmPitt-Greenville
$430
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville, North Carolina to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Greenville, North Carolina to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Thu 12/4

5:00 am-10:30 am

1 stop5h 30m

Knoxville McGhee Tyson

Sun 12/7

8:13 pm-11:59 pm

1 stop3h 46m

$327

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sat 12/6

5:00 am-3:46 pm

2 stops10h 46m

Knoxville McGhee Tyson

Sun 12/7

8:13 pm-11:59 pm

1 stop3h 46m

$356

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Thu 12/4

5:00 am-3:54 pm

2 stops10h 54m

Knoxville McGhee Tyson

Sun 12/7

8:13 pm-11:59 pm

1 stop3h 46m

$430

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Wed 12/17

7:16 pm-10:55 pm

1 stop3h 39m

Knoxville McGhee Tyson

Wed 12/24

5:00 am-10:36 am

1 stop5h 36m

$431

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Wed 12/17

6:00 am-9:36 pm

2 stops15h 36m

Knoxville McGhee Tyson

Wed 12/24

7:00 am-10:36 am

1 stop3h 36m

$450

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Wed 3/25

3:55 pm-9:29 pm

1 stop5h 34m

Knoxville McGhee Tyson

Sat 3/28

6:58 am-10:22 am

1 stop3h 24m

$452

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Wed 3/25

5:12 am-9:43 pm

2 stops16h 31m

Knoxville McGhee Tyson

Sat 3/28

6:58 am-10:22 am

1 stop3h 24m

$476

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Wed 12/17

6:00 am-9:36 pm

2 stops15h 36m

Knoxville McGhee Tyson

Wed 12/24

5:15 am-5:31 pm

2 stops12h 16m

$506

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Sat 12/6

5:00 am-3:46 pm

2 stops10h 46m

Knoxville McGhee Tyson

Sun 12/7

6:00 am-5:34 pm

2 stops11h 34m

$562

GreenvilleKnoxville

PGV - TYS

PGVTYS

Pitt-Greenville

Mon 11/17

6:00 am-9:50 am

1 stop3h 50m

Knoxville McGhee Tyson

Fri 11/21

5:51 pm-11:59 pm

1 stop6h 08m

$597

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Knoxville from

How to get the cheapest flight ticket from Greenville, North Carolina to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Greenville, North Carolina according to our data. American Airlines is the first choice among our users, with 81% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When to book flights from Greenville, North Carolina to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville, North Carolina to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville, North Carolina to Knoxville (PGV to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville, North Carolina to Knoxville

Direct flights

None
There are no direct flights from Greenville, North Carolina to Knoxville. There are no popular flight routes from Greenville, North Carolina to Knoxville.
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  • How far is Pitt-Greenville to Knoxville McGhee Tyson by plane?

    The distance between Pitt-Greenville and Knoxville McGhee Tyson is about 367.8 mi. Flights usually cover this in 3h 39m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Pitt-Greenville Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Greenville, North Carolina to Knoxville?

Best airlines flying from Greenville, North Carolina to Knoxville

Compare and see reviews for airlines that fly from Greenville, North Carolina to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $218Free CancellationRating
7.2
11,037 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Greenville to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Greenville to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Greenville to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Greenville to Knoxville?

Once you have performed a search for Greenville to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Greenville to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Greenville to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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