Cheap flights from Greenville to Portland from $190

The cheapest month to fly to Portland from Greenville is in October. Flight prices, which tend to average around $376, are often lower during this time because this is during the off-season. If you don’t want to visit Portland in October, then you should wait until September to fly from Greenville, when ticket prices are also cheap, with an average price of $386.

You are more likely to see cheaper flights to Portland from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Portland for around $461 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Portland from Greenville for as low as $350 on momondo.

You could potentially save up to 39% on your flight if you consider stops on a Greenville to Portland flight.

As of April 2026, prices for Greenville to Portland flights are approximately 42% cheaper when compared to flights at the same time last year.

Southwest, American Airlines, and Delta are the most popular carriers operating from Greenville to Portland

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Portland from Greenville according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Portland. Keep in mind that there are 6 different airlines that fly to Portland on a routine basis, so you have a few additional options to choose from.

Atlanta (ATL) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Dallas (DFW) offer the lowest average round-trip price of $336.

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 7h 40m.

Charlotte (CLT) has the shortest average layover time for this route: 0h 57m.