What is the cheapest airline that flies from Greenville to Buffalo?

American Airlines and Delta are the most popular carriers operating from Greenville to Buffalo

Which layover airport has the shortest travel time from Greenville to Buffalo?

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 4h 21m.

Which airport is the most popular layover for flights between Greenville and Buffalo?

Philadelphia (PHL) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to Buffalo?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Buffalo from Greenville according to our data. American Airlines is the first choice among our users, with 86% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 4 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Greenville to Buffalo?

Philadelphia (PHL) has the shortest average layover time for this route: 1h 15m.

Which layover airport offers the lowest fares from Greenville to Buffalo?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $236.

When did momondo last update prices for flights from Greenville Airport to Buffalo Airport?

Prices for flights from Greenville Airport to Buffalo Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Greenville Airport to Buffalo Airport?

As of May 2026, there are 3 operators available to choose from for flights from Greenville Airport to Buffalo Airport.

How old do you have to be to fly from Greenville Airport to Buffalo Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Buffalo Airport.

What documentation or ID do you need to fly to Buffalo Airport?

The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$144 Cheap Flights from Greenville to Buffalo in 2026

Q: What is the typical price of a round-trip flight between Greenville and Buffalo?

Prices are currently low for flights on this route. Typical prices usually range from $462 to $337. The lowest price recently found on this route was $287.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Greenville to Buffalo

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:07 pm - 11:32 pm

GSP

BUF

5h 25m

1 stop

3:54 pm - 9:47 pm

BUF

GSP

5h 53m

1 stop

$287Delta

Tue, Jun 23 - Tue, Jul 7

8:00 am - 2:10 pm

GSP

BUF

6h 10m

1 stop

6:10 am - 10:10 am

BUF

GSP

4h 00m

1 stop

$304Southwest

Sat, Oct 3 - Tue, Oct 6

8:00 am - 2:10 pm

GSP

BUF

6h 10m

1 stop

11:10 am - 9:05 pm

BUF

GSP

9h 55m

2 stops

$309Southwest

Sat, Oct 3 - Tue, Oct 6

7:10 am - 11:24 am

GSP

BUF

4h 14m

1 stop

10:20 am - 2:51 pm

BUF

GSP

4h 31m

1 stop

$337Delta

Wed, Jun 24 - Fri, Jul 3

7:00 am - 3:40 pm

GSP

BUF

8h 40m

2 stops

5:25 pm - 9:20 pm

BUF

GSP

3h 55m

1 stop

$342Southwest

Wed, Jul 29 - Sat, Aug 1

7:14 pm - 11:52 pm

GSP

BUF

4h 38m

1 stop

7:32 pm - 11:52 pm

BUF

GSP

4h 20m

1 stop

$347American Airlines

Fri, Jun 19 - Tue, Jun 23

1:50 pm - 10:45 pm

GSP

BUF

8h 55m

1 stop

2:50 pm - 10:55 pm

BUF

GSP

8h 05m

2 stops

$348Southwest

Wed, Jul 22 - Fri, Jul 31

3:19 pm - 1:53 pm

GSP

BUF

22h 34m

2 stops

7:57 pm - 7:35 am

BUF

GSP

11h 38m

1 stop

$351Multiple Airlines

Thu, Jul 9 - Wed, Jul 15

5:44 am - 11:11 am

GSP

BUF

5h 27m

1 stop

6:00 am - 10:47 am

BUF

GSP

4h 47m

1 stop

$356Delta

Sun, Jul 26 - Thu, Jul 30

12:55 pm - 12:10 am

GSP

BUF

11h 15m

2 stops

11:00 am - 7:00 pm

BUF

GSP

8h 00m

2 stops

$363Southwest

Fri, Jun 19 - Tue, Jun 23

Delta flights from Greenville to Buffalo

Our best Delta deals on Greenville to Buffalo flight tickets

Delta

Jun 23

GSP6:07 pmGreenville

5h 25m

1 stop

BUF11:32 pmBuffalo

Jun 30

BUF6:29 amBuffalo

3h 58m

1 stop

GSP10:27 amGreenville

$287

Delta

Oct 3

GSP3:35 pmGreenville

5h 45m

1 stop

BUF9:20 pmBuffalo

Oct 6

BUF7:40 pmBuffalo

3h 57m

1 stop

GSP11:37 pmGreenville

$304

Delta

Jun 24

GSP7:10 amGreenville

4h 14m

1 stop

BUF11:24 amBuffalo

Jul 4

BUF6:29 amBuffalo

5h 37m

1 stop

GSP12:06 pmGreenville

$337

United Airlines flights from Greenville to Buffalo

Our best United Airlines deals on Greenville to Buffalo flight tickets

United Airlines

Oct 21

GSP6:20 amGreenville

7h 26m

2 stops

BUF1:46 pmBuffalo

Oct 27

BUF6:00 amBuffalo

15h 11m

3 stops

GSP9:11 pmGreenville

$383

United Airlines

Aug 15

GSP7:47 pmGreenville

3h 57m

1 stop

BUF11:44 pmBuffalo

Aug 19

BUF10:30 amBuffalo

6h 32m

1 stop

GSP5:02 pmGreenville

$384

United Airlines

Oct 3

GSP2:16 pmGreenville

6h 15m

1 stop

BUF8:31 pmBuffalo

Oct 6

BUF6:00 amBuffalo

7h 25m

2 stops

GSP1:25 pmGreenville

$389

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Tue 6/23

6:07 pm-11:32 pm

1 stop5h 25m

Buffalo

Tue 7/7

3:54 pm-9:47 pm

1 stop5h 53m

$287

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 10/3

8:00 am-2:10 pm

1 stop6h 10m

Buffalo

Tue 10/6

6:10 am-10:10 am

1 stop4h 00m

$304

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 10/3

8:00 am-2:10 pm

1 stop6h 10m

Buffalo

Tue 10/6

11:10 am-9:05 pm

2 stops9h 55m

$309

Quickest round-trip

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Wed 6/24

7:10 am-11:24 am

1 stop4h 14m

Buffalo

Fri 7/3

10:20 am-2:51 pm

1 stop4h 31m

$337

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Wed 7/29

7:00 am-3:40 pm

2 stops8h 40m

Buffalo

Sat 8/1

5:25 pm-9:20 pm

1 stop3h 55m

$342

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 6/19

7:14 pm-11:52 pm

1 stop4h 38m

Buffalo

Tue 6/23

7:32 pm-11:52 pm

1 stop4h 20m

$347

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Wed 7/22

1:50 pm-10:45 pm

1 stop8h 55m

Buffalo

Fri 7/31

2:50 pm-10:55 pm

2 stops8h 05m

$348

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 7/9

3:19 pm-1:53 pm

2 stops22h 34m

Buffalo

Wed 7/15

7:57 pm-7:35 am

1 stop11h 38m

$351

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sun 7/26

5:44 am-11:11 am

1 stop5h 27m

Buffalo

Thu 7/30

6:00 am-10:47 am

1 stop4h 47m

$356

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 6/19

12:55 pm-12:10 am

2 stops11h 15m

Buffalo

Tue 6/23

11:00 am-7:00 pm

2 stops8h 00m

$363

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Greenville to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Greenville and Buffalo?

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of September, then book flights to Buffalo from Greenville during November instead. Flights to Buffalo in November, while not as cheap as those in September, still average around $336.

How have Greenville to Buffalo flight prices changed over time?

When to book flights from Greenville to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Buffalo according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Greenville to Buffalo (GSP to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Buffalo

Fastest flight time	3h 57m
Direct flights	None

The fastest flight from Greenville to Buffalo takes 3h 57m

There are no direct flights from Greenville to Buffalo. There are no popular flight routes from Greenville to Buffalo.

Search flight deals

Frequently asked questions about flying from Greenville to Buffalo

How far is Greenville to Buffalo by plane?
A flight from Greenville to Buffalo will travel around 585.9 mi. 3h 57m is a normal flight duration for this route.
When did momondo last update prices for flights from Greenville Airport to Buffalo Airport?
Prices for flights from Greenville Airport to Buffalo Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Greenville Airport to Buffalo Airport?
As of May 2026, there are 3 operators available to choose from for flights from Greenville Airport to Buffalo Airport.
How old do you have to be to fly from Greenville Airport to Buffalo Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Buffalo Airport.
What documentation or ID do you need to fly to Buffalo Airport?
The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Greenville to Buffalo?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Greenville to Buffalo is American Airlines (63% of total bookings). The next most popular airlines are Delta (22%) and Southwest (15%).

Best airlines flying from Greenville to Buffalo

Compare and see reviews for airlines that fly from Greenville to Buffalo with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $226	Free Cancellation	Rating 7.9 8,424 reviews	Search Delta flights
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.1 11,629 reviews	Search American Airlines flights
Southwest	PriceFrom $287	Free Cancellation	Rating 8.0 4,266 reviews	Search Southwest flights

Batavia

Cheektowaga

Amherst

Tonawanda

Williamsville

Grand Island

Orchard Park

Bowmansville

West Seneca

Lockport

East Aurora

Eden

Angola

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Buffalo?

It is quick and easy to find Greenville to Buffalo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Buffalo that suits you.

Can I find flights from Greenville to Buffalo with flexible booking policies on momondo?

Yes. All flights to Buffalo from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Greenville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Greenville to Buffalo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Buffalo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Buffalo and let you know when they change.

An easier way to manage your Buffalo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Thu 6/25

Thu 7/2

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from Greenville

Complete your trip

Feeling lucky

Cheap flights from Greenville to Buffalo from $144

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Buffalo departing on 6/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Greenville to Buffalo

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Delta flights from Greenville to Buffalo

Our best Delta deals on Greenville to Buffalo flight tickets

United Airlines flights from Greenville to Buffalo

Our best United Airlines deals on Greenville to Buffalo flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.

See travel insights to Buffalo from

How to get the cheapest flight ticket from Greenville to Buffalo

What is the typical price of a round-trip flight between Greenville and Buffalo?

What is the cheapest month to fly to Buffalo?

How have Greenville to Buffalo flight prices changed over time?

What is the cheapest airline that flies from Greenville to Buffalo?

What airlines fly to Buffalo?

Which airport is the most popular layover for flights between Greenville and Buffalo?

Which layover airport offers the lowest fares from Greenville to Buffalo?

Which layover airport has the shortest travel time from Greenville to Buffalo?

Which layover airport has the shortest connection time from Greenville to Buffalo?

When to book flights from Greenville to Buffalo

Cheap Greenville to Buffalo (GSP to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Buffalo

Fastest flight time

Direct flights

Frequently asked questions about flying from Greenville to Buffalo

Best airlines flying from Greenville to Buffalo

Compare and see reviews for airlines that fly from Greenville to Buffalo with momondo

Traveling to a place near Buffalo?

Why use momondo?

An easier way to manage your Buffalo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing New York

Fly your favorite airline to Buffalo

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Buffalo

List of cabin classes available on flights landing in Buffalo. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Greenville

According to popular flight searches on momondo this year

Complete your trip to Buffalo

Explore popular destinations other users love

According to popular flight searches on momondo this year