Cheap flights from Greenville to Buffalo from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Buffalo departing on 8/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Greenville to Buffalo

Cheap round-trip flights

Southwest Logo
1:50 pm - 8:45 pmGSP-BUF
6h 55m1 stop
Southwest Logo
5:30 am - 10:00 amBUF-GSP
4h 30m1 stop
$216Southwest
Find Deal
Thu, Oct 16 - Tue, Oct 21
Delta Logo
7:45 pm - 11:37 pmGSP-BUF
3h 52m1 stop
Delta Logo
6:00 am - 11:24 amBUF-GSP
5h 24m1 stop
$227Delta
Find Deal
Mon, Sep 15 - Thu, Sep 18
Southwest Logo
1:50 pm - 8:45 pmGSP-BUF
6h 55m1 stop
Southwest Logo
8:45 am - 7:55 pmBUF-GSP
11h 10m2 stops
$237Southwest
Find Deal
Thu, Oct 16 - Tue, Oct 21
Southwest Logo
8:25 am - 4:35 pmGSP-BUF
8h 10m1 stop
Southwest Logo
5:30 am - 10:00 amBUF-GSP
4h 30m1 stop
$246Southwest
Find Deal
Fri, Oct 17 - Tue, Oct 21
American Airlines Logo
6:00 am - 12:43 pmGSP-BUF
6h 43m2 stops
American Airlines Logo
6:00 am - 10:16 amBUF-GSP
4h 16m1 stop
$256American Airlines
Find Deal
Sat, Aug 30 - Thu, Sep 4
Delta Logo
5:30 am - 10:57 amGSP-BUF
5h 27m1 stop
Delta Logo
6:20 am - 10:37 amBUF-GSP
4h 17m1 stop
$257Delta
Find Deal
Thu, Sep 4 - Sun, Sep 7
American Airlines Logo
8:00 am - 12:43 pmGSP-BUF
4h 43m1 stop
American Airlines Logo
6:00 am - 10:16 amBUF-GSP
4h 16m1 stop
$259American Airlines
Find Deal
Sat, Aug 30 - Thu, Sep 4
Southwest Logo
8:25 am - 4:35 pmGSP-BUF
8h 10m1 stop
Southwest Logo
8:45 am - 7:55 pmBUF-GSP
11h 10m2 stops
$266Southwest
Find Deal
Fri, Oct 17 - Tue, Oct 21
United Airlines Logo
2:55 pm - 6:39 pmGSP-BUF
3h 44m1 stop
United Airlines Logo
10:00 pm - 2:58 amBUF-GSP
4h 58m1 stop
$287United Airlines
Find Deal
Thu, Nov 27 - Sun, Nov 30
United Airlines Logo
9:10 am - 6:39 pmGSP-BUF
9h 29m2 stops
United Airlines Logo
10:00 pm - 2:58 amBUF-GSP
4h 58m1 stop
$292United Airlines
Find Deal
Thu, Nov 27 - Sun, Nov 30

Southwest flights from Greenville to Buffalo

Our best Southwest deals on Greenville to Buffalo flight tickets
Southwest
Oct 16
GSP1:50 pmGreenville
6h 55m
1 stop
BUF8:45 pmBuffalo
Oct 21
BUF5:30 amBuffalo
4h 30m
1 stop
GSP10:00 amGreenville
Southwest
Oct 16
GSP1:50 pmGreenville
6h 55m
1 stop
BUF8:45 pmBuffalo
Oct 21
BUF8:45 amBuffalo
11h 10m
2 stops
GSP7:55 pmGreenville
Southwest
Oct 17
GSP8:25 amGreenville
8h 10m
1 stop
BUF4:35 pmBuffalo
Oct 21
BUF5:30 amBuffalo
4h 30m
1 stop
GSP10:00 amGreenville

American Airlines flights from Greenville to Buffalo

Our best American Airlines deals on Greenville to Buffalo flight tickets
American Airlines
Aug 30
GSP6:00 amGreenville
6h 43m
2 stops
BUF12:43 pmBuffalo
Sep 4
BUF6:00 amBuffalo
4h 16m
1 stop
GSP10:16 amGreenville
American Airlines
Aug 30
GSP8:00 amGreenville
4h 43m
1 stop
BUF12:43 pmBuffalo
Sep 4
BUF6:00 amBuffalo
4h 16m
1 stop
GSP10:16 amGreenville
American Airlines
Nov 2
GSP7:11 amGreenville
4h 22m
1 stop
BUF11:33 amBuffalo
Nov 4
BUF5:26 pmBuffalo
5h 45m
2 stops
GSP11:11 pmGreenville

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2025.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 10/16

1:50 pm-8:45 pm

1 stop6h 55m

Buffalo

Tue 10/21

5:30 am-10:00 am

1 stop4h 30m

$216

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Mon 9/15

7:45 pm-11:37 pm

1 stop3h 52m

Buffalo

Thu 9/18

6:00 am-11:24 am

1 stop5h 24m

$227

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 10/16

1:50 pm-8:45 pm

1 stop6h 55m

Buffalo

Tue 10/21

8:45 am-7:55 pm

2 stops11h 10m

$237

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 10/17

8:25 am-4:35 pm

1 stop8h 10m

Buffalo

Tue 10/21

5:30 am-10:00 am

1 stop4h 30m

$246

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 8/30

6:00 am-12:43 pm

2 stops6h 43m

Buffalo

Thu 9/4

6:00 am-10:16 am

1 stop4h 16m

$256

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 9/4

5:30 am-10:57 am

1 stop5h 27m

Buffalo

Sun 9/7

6:20 am-10:37 am

1 stop4h 17m

$257

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 8/30

8:00 am-12:43 pm

1 stop4h 43m

Buffalo

Thu 9/4

6:00 am-10:16 am

1 stop4h 16m

$259

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 10/17

8:25 am-4:35 pm

1 stop8h 10m

Buffalo

Tue 10/21

8:45 am-7:55 pm

2 stops11h 10m

$266

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 11/27

2:55 pm-6:39 pm

1 stop3h 44m

Buffalo

Sun 11/30

10:00 pm-2:58 am

1 stop4h 58m

$287

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 11/27

9:10 am-6:39 pm

2 stops9h 29m

Buffalo

Sun 11/30

10:00 pm-2:58 am

1 stop4h 58m

$292

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Greenville to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Buffalo?

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of March, then book flights to Buffalo from Greenville during September instead. Flights to Buffalo in September, while not as cheap as those in March, still average around $296.

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Saturday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $335. Flights from Greenville to Buffalo on a Sunday will generally be more expensive and average around $530. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

In the afternoon is the cheapest time of day to fly from Greenville to Buffalo when you can find flight prices for as low as $356. Flying to Buffalo in the afternoon is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Buffalo, so prices are often more expensive at around $371 per ticket.

How have Greenville to Buffalo flight prices changed over time?

As of August 2025, prices for Greenville to Buffalo flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Buffalo (GSP to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Buffalo

Best Price Found

$114

Fastest flight time

3h 35m

Direct flights

None

Airports in Buffalo

1 airport
The best one-way flight to Buffalo from Greenville in the past 72 hours is $114. The best round-trip flight deal from Greenville to Buffalo found on momondo in the last 72 hours is $216.
The fastest flight from Greenville to Buffalo takes 3h 35m
There are no direct flights from Greenville to Buffalo. Popular non-direct route for this connection is Greenville Airport - Buffalo Airport.
There is 1 airport near Buffalo: Buffalo (BUF)
  • How far is Greenville to Buffalo by plane?

    A flight from Greenville to Buffalo will travel around 585.9 mi. 3h 35m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Greenville Airport to Buffalo Airport?

    Prices for flights from Greenville Airport to Buffalo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Greenville Airport to Buffalo Airport?

  • How old do you have to be to fly from Greenville Airport to Buffalo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Greenville to Buffalo?

Best airlines flying from Greenville to Buffalo

Compare and see reviews for airlines that fly from Greenville to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $216Free CancellationRating
8.0
7,985 reviews
Search Delta flights
SouthwestPriceFrom $233Free CancellationRating
8.0
4,244 reviews
Search Southwest flights
American AirlinesPriceFrom $236Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Williamsville
Amherst
Tonawanda
Cheektowaga
Grand Island
Lockport
Orchard Park
West Seneca
East Aurora
Bowmansville
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Buffalo?

It is quick and easy to find Greenville to Buffalo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Buffalo that suits you.

Can I find flights from Greenville to Buffalo with flexible booking policies on momondo?

Yes. All flights to Buffalo from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Greenville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Greenville to Buffalo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Buffalo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Buffalo and let you know when they change.

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1 adult
Mon 8/11
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