Which layover airport has the shortest connection time from Greenville to Buffalo?

Philadelphia (PHL) has the shortest average layover time for this route: 1h 15m.

Which airport is the most popular layover for flights between Greenville and Buffalo?

Philadelphia (PHL) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Greenville to Buffalo?

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 4h 21m.

What airlines fly to Buffalo?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Buffalo from Greenville according to our data. American Airlines is the first choice among our users, with 82% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 5 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

Which layover airport offers the lowest fares from Greenville to Buffalo?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $236.

When did momondo last update prices for flights from Greenville Airport to Buffalo Airport?

Prices for flights from Greenville Airport to Buffalo Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Greenville Airport to Buffalo Airport?

As of December 2025, there are 3 operators available to choose from for flights from Greenville Airport to Buffalo Airport.

How old do you have to be to fly from Greenville Airport to Buffalo Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Buffalo Airport.

What documentation or ID do you need to fly to Buffalo Airport?

The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$232 Cheap Flights from Greenville to Buffalo in 2025/26

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5:39 am - 11:07 am

GSP

BUF

5h 28m1 stop

5:27 pm - 10:16 pm

BUF

GSP

4h 49m1 stop

$276American Airlines

Kam, Jan 1 - Sel, Jan 6

7:42 pm - 11:42 pm

GSP

BUF

4h 00m1 stop

7:00 am - 11:24 am

BUF

GSP

4h 24m1 stop

$303American Airlines

Sen, Jan 12 - Sen, Jan 19

10:32 am - 4:57 pm

GSP

BUF

6h 25m2 stops

6:53 pm - 11:26 pm

BUF

GSP

4h 33m1 stop

$308American Airlines

Sen, Jan 12 - Sen, Jan 19

7:00 pm - 8:58 am

GSP

BUF

13h 58m1 stop

11:27 am - 10:19 pm

BUF

GSP

10h 52m1 stop

$335American Airlines

Jum, Jan 9 - Jum, Jan 16

11:15 am - 9:55 pm

GSP

BUF

10h 40m2 stops

5:50 am - 11:55 am

BUF

GSP

6h 05m2 stops

$341Southwest

Sen, Jan 12 - Sen, Jan 19

10:45 am - 9:15 pm

GSP

BUF

10h 30m2 stops

5:25 am - 10:10 am

BUF

GSP

4h 45m1 stop

$346Southwest

Sen, Feb 23 - Kam, Feb 26

6:07 am - 10:58 am

GSP

BUF

4h 51m1 stop

11:34 am - 10:08 pm

BUF

GSP

10h 34m1 stop

$356American Airlines

Kam, Mar 12 - Sen, Mar 16

4:39 pm - 5:38 pm

GSP

BUF

24h 59m1 stop

8:58 pm - 4:15 pm

BUF

GSP

43h 17m2 stops

$362Multiple Airlines

Jum, Jan 9 - Jum, Jan 16

5:39 am - 11:07 am

GSP

BUF

5h 28m1 stop

11:31 am - 10:19 pm

BUF

GSP

10h 48m1 stop

$366American Airlines

Min, Jan 4 - Min, Jan 11

8:50 am - 3:59 pm

GSP

BUF

7h 09m1 stop

3:50 pm - 10:00 pm

BUF

GSP

6h 10m1 stop

$367Delta

Jum, Apr 10 - Jum, Apr 17

American Airlines flights from Greenville to Buffalo

Our best American Airlines deals on Greenville to Buffalo flight tickets

American Airlines

Jan 1

GSP5:39 amGreenville

5h 28m

1 stop

BUF11:07 amBuffalo

Jan 6

BUF5:27 pmBuffalo

4h 49m

1 stop

GSP10:16 pmGreenville

$276

Find similar

American Airlines

Jan 12

GSP7:42 pmGreenville

4h 00m

1 stop

BUF11:42 pmBuffalo

Jan 19

BUF7:00 amBuffalo

4h 24m

1 stop

GSP11:24 amGreenville

$303

Find similar

American Airlines

Jan 12

GSP10:32 amGreenville

6h 25m

2 stops

BUF4:57 pmBuffalo

Jan 19

BUF6:53 pmBuffalo

4h 33m

1 stop

GSP11:26 pmGreenville

$308

Find similar

Southwest flights from Greenville to Buffalo

Our best Southwest deals on Greenville to Buffalo flight tickets

Southwest

Jan 12

GSP11:15 amGreenville

10h 40m

2 stops

BUF9:55 pmBuffalo

Jan 19

BUF5:50 amBuffalo

6h 05m

2 stops

GSP11:55 amGreenville

$341

Find similar

Southwest

Feb 23

GSP10:45 amGreenville

10h 30m

2 stops

BUF9:15 pmBuffalo

Feb 26

BUF5:25 amBuffalo

4h 45m

1 stop

GSP10:10 amGreenville

$346

Find similar

Southwest

Mar 12

GSP1:55 pmGreenville

3h 40m

1 stop

BUF5:35 pmBuffalo

Mar 16

BUF12:05 pmBuffalo

10h 40m

2 stops

GSP10:45 pmGreenville

$372

Find similar

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Kam 1/1

5:39 am-11:07 am

1 stop5h 28m

Buffalo

Sel 1/6

5:27 pm-10:16 pm

1 stop4h 49m

$276

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sen 1/12

7:42 pm-11:42 pm

1 stop4h 00m

Buffalo

Sen 1/19

7:00 am-11:24 am

1 stop4h 24m

$303

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sen 1/12

10:32 am-4:57 pm

2 stops6h 25m

Buffalo

Sen 1/19

6:53 pm-11:26 pm

1 stop4h 33m

$308

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Jum 1/9

7:00 pm-8:58 am

1 stop13h 58m

Buffalo

Jum 1/16

11:27 am-10:19 pm

1 stop10h 52m

$335

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sen 1/12

11:15 am-9:55 pm

2 stops10h 40m

Buffalo

Sen 1/19

5:50 am-11:55 am

2 stops6h 05m

$341

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sen 2/23

10:45 am-9:15 pm

2 stops10h 30m

Buffalo

Kam 2/26

5:25 am-10:10 am

1 stop4h 45m

$346

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Kam 3/12

6:07 am-10:58 am

1 stop4h 51m

Buffalo

Sen 3/16

11:34 am-10:08 pm

1 stop10h 34m

$356

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Jum 1/9

4:39 pm-5:38 pm

1 stop24h 59m

Buffalo

Jum 1/16

8:58 pm-4:15 pm

2 stops43h 17m

$362

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Min 1/4

5:39 am-11:07 am

1 stop5h 28m

Buffalo

Min 1/11

11:31 am-10:19 pm

1 stop10h 48m

$366

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Jum 4/10

8:50 am-3:59 pm

1 stop7h 09m

Buffalo

Jum 4/17

3:50 pm-10:00 pm

1 stop6h 10m

$367

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Greenville to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of September, then book flights to Buffalo from Greenville during March instead. Flights to Buffalo in March, while not as cheap as those in September, still average around $266.

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Saturday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $335. Flights from Greenville to Buffalo on a Sunday will generally be more expensive and average around $530. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

In the afternoon is the cheapest time of day to fly from Greenville to Buffalo when you can find flight prices for as low as $356. Flying to Buffalo in the afternoon is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Buffalo, so prices are often more expensive at around $371 per ticket.

How have Greenville to Buffalo flight prices changed over time?

As of December 2025, prices for Greenville to Buffalo flights are approximately 59% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Buffalo according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Greenville to Buffalo (GSP to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Buffalo

Fastest flight time	3h 51m
Direct flights	None

The fastest flight from Greenville to Buffalo takes 3h 51m

There are no direct flights from Greenville to Buffalo. There are no popular flight routes from Greenville to Buffalo.

Search flight deals

How far is Greenville to Buffalo by plane?
A flight from Greenville to Buffalo will travel around 585.9 mi. 3h 51m is a normal flight duration for this route.
When did momondo last update prices for flights from Greenville Airport to Buffalo Airport?
Prices for flights from Greenville Airport to Buffalo Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Greenville Airport to Buffalo Airport?
As of December 2025, there are 3 operators available to choose from for flights from Greenville Airport to Buffalo Airport.
How old do you have to be to fly from Greenville Airport to Buffalo Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Buffalo Airport.
What documentation or ID do you need to fly to Buffalo Airport?
The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Greenville to Buffalo?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Greenville to Buffalo is American Airlines (61% of total bookings). The next most popular airlines are Delta (23%) and Southwest (16%).

Best airlines flying from Greenville to Buffalo

Compare and see reviews for airlines that fly from Greenville to Buffalo with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 8,007 reviews	Search Delta flights
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.2 11,054 reviews	Search American Airlines flights
Southwest	PriceFrom $286	Free Cancellation	Rating 7.9 4,251 reviews	Search Southwest flights

Batavia

Cheektowaga

Amherst

Tonawanda

Grand Island

Williamsville

Orchard Park

Lockport

West Seneca

Bowmansville

East Aurora

Eden

Angola

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Buffalo?

It is quick and easy to find Greenville to Buffalo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Buffalo that suits you.

Can I find flights from Greenville to Buffalo with flexible booking policies on momondo?

Yes. All flights to Buffalo from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Greenville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Greenville to Buffalo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Buffalo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Buffalo and let you know when they change.

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Cheap flights from Greenville to Buffalo from $276

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Buffalo departing on 1/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Greenville to Buffalo

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of September, then book flights to Buffalo from Greenville during March instead. Flights to Buffalo in March, while not as cheap as those in September, still average around $266.

What is the cheapest day to depart on your flight to Buffalo?

What is the cheapest time of day to depart on your flight to Buffalo?

How have Greenville to Buffalo flight prices changed over time?

As of December 2025, prices for Greenville to Buffalo flights are approximately 59% more expensive when compared to flights at the same time last year.

What airlines fly to Buffalo?

Which airport is the most popular layover for flights between Greenville and Buffalo?

Philadelphia (PHL) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Greenville to Buffalo?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $236.

Which layover airport has the shortest travel time from Greenville to Buffalo?

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 4h 21m.

Which layover airport has the shortest connection time from Greenville to Buffalo?

Philadelphia (PHL) has the shortest average layover time for this route: 1h 15m.

When to book flights from Greenville to Buffalo

Cheap Greenville to Buffalo (GSP to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Buffalo

Fastest flight time

Direct flights

How far is Greenville to Buffalo by plane?

When did momondo last update prices for flights from Greenville Airport to Buffalo Airport?

How many operators does momondo search for flights from Greenville Airport to Buffalo Airport?

How old do you have to be to fly from Greenville Airport to Buffalo Airport?

What documentation or ID do you need to fly to Buffalo Airport?

What is the most popular airline from Greenville to Buffalo?

Best airlines flying from Greenville to Buffalo

Compare and see reviews for airlines that fly from Greenville to Buffalo with momondo

Traveling to a place near Buffalo?

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Buffalo?

Can I find flights from Greenville to Buffalo with flexible booking policies on momondo?

How can momondo help me find flights from Greenville to Buffalo?

I’m not ready to book a flight from Greenville to Buffalo right now. Can momondo alert me if prices change?

An easier way to manage your Buffalo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing New York