Cheap flights from Frankfurt am Main to St. Louis from $434

In general, June is the cheapest month to fly from Frankfurt am Main to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $465. The month of January is another great option to travel to St. Louis, with average flight prices from Frankfurt am Main averaging around $500.

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $1,018. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $1,057. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Fly from Frankfurt am Main to Lambert-St Louis for the best Frankfurt am Main - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Frankfurt am Main when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $890 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Frankfurt am Main for as low as $755 on momondo.

1 flights are operational daily from Frankfurt am Main to St. Louis as of June 2026. The most popular departure time for this route is 10:00AM, with 100% of flights per day taking off at noon.

As of June 2026, there are 10 flights per week flying from Frankfurt am Main to St. Louis. The most common day of the week flights depart is Mon, with 20% of flights taking off on this day.