Cheap flights from Fort Myers to Missouri from $114

In general, January is the cheapest month to fly from Fort Myers to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $417. If you aren’t able to travel to Missouri during the month of January, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $419.

The cheapest day to depart from Fort Myers to Missouri is on a Sunday when prices can be found for as low as $401. Flights from Fort Myers to Missouri on a Friday will generally be more expensive and average around $487. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Missouri is in the afternoon. momondo users have found flights departing from Fort Myers to Missouri in the afternoon for as low as $424. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the evening, with an average ticket price of $476. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Fort Myers SW Florida Intl to Kansas City for the best Fort Myers SW Florida Intl - Missouri flight prices

You are more likely to see cheaper flights to Missouri from Fort Myers when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $470 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Fort Myers for as low as $373 on momondo.

There is only 1 cabin class available to choose from on Fort Myers to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, Southwest, and United Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Missouri

Southwest, Delta and American Airlines are the top three most popular airlines that fly to Missouri from Fort Myers according to our data. Southwest is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 5 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

As of October 2026, there are 1 flights per day flying from Fort Myers to Missouri. The most common time of day flights depart is 6:00AM, with 53% of flights taking off at noon.

The number of flights available between Fort Myers and Missouri is 12 per week as of October 2026. The most frequent departure day is Mon, with 33% of weekly flights leaving on this day.