What is the cheapest airline that flies from Fort Myers SW Florida Intl to Des Moines?

Frontier, United Airlines, and American Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Des Moines

How many flights depart from Fort Myers to Des Moines on average per week?

The number of flights available between Fort Myers and Des Moines is 2 per week as of February 2026. The most frequent departure day is Mon, with 50% of weekly flights leaving on this day.

What airlines fly to Des Moines?

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Des Moines from Fort Myers according to our data. American Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

Prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

As of February 2026, there are 2 operators available to choose from for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport.

How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Fort Myers SW Florida Intl Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$68 Cheap Flights from Fort Myers to Des Moines in 2026

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10:54 am - 1:13 pm

RSW

DSM

3h 19mnonstop

6:00 am - 10:04 am

DSM

RSW

3h 04mnonstop

$308Allegiant Air

lun, apr 6 - ven, apr 10

7:01 am - 12:29 pm

RSW

DSM

6h 28m

1 stop

6:15 am - 2:37 pm

DSM

RSW

7h 22m

1 stop

$371United Airlines

ven, apr 10 - mer, mag 6

7:01 am - 12:29 pm

RSW

DSM

6h 28m

1 stop

5:30 am - 3:57 pm

DSM

RSW

9h 27m

2 stops

$376United Airlines

ven, apr 10 - mer, mag 6

4:38 pm - 9:12 pm

RSW

DSM

5h 34m

1 stop

6:00 am - 2:44 pm

DSM

RSW

7h 44m

1 stop

$407United Airlines

ven, mag 22 - mar, mag 26

5:27 pm - 11:48 pm

RSW

DSM

7h 21m

1 stop

2:02 pm - 8:42 pm

DSM

RSW

5h 40m

1 stop

$417American Airlines

gio, feb 26 - gio, mar 5

10:54 am - 1:13 pm

RSW

DSM

3h 19mnonstop

8:14 pm - 10:37 am

DSM

RSW

37h 23m

2 stops

$423Multiple Airlines

lun, apr 6 - ven, apr 10

6:23 pm - 11:40 pm

RSW

DSM

6h 17m

1 stop

5:00 am - 12:18 pm

DSM

RSW

6h 18m

1 stop

$427American Airlines

gio, feb 26 - gio, mar 5

6:23 pm - 11:40 pm

RSW

DSM

6h 17m

1 stop

5:00 am - 1:04 pm

DSM

RSW

7h 04m

2 stops

$433American Airlines

gio, feb 26 - gio, mar 5

12:55 pm - 11:05 pm

RSW

DSM

11h 10m

2 stops

5:30 am - 12:45 pm

DSM

RSW

6h 15m

1 stop

$438Southwest

ven, mag 22 - mar, mag 26

6:00 am - 1:17 pm

RSW

DSM

8h 17m

1 stop

5:00 am - 1:04 pm

DSM

RSW

7h 04m

2 stops

$440American Airlines

gio, feb 26 - gio, mar 5

United Airlines flights from Fort Myers to Des Moines

Our best United Airlines deals on Fort Myers to Des Moines flight tickets

United Airlines

Apr 10

RSW7:01 amFort Myers SW Florida Intl

6h 28m

1 stop

DSM12:29 pmDes Moines

May 6

DSM6:15 amDes Moines

7h 22m

1 stop

RSW2:37 pmFort Myers SW Florida Intl

$371

United Airlines

Apr 10

RSW7:01 amFort Myers SW Florida Intl

6h 28m

1 stop

DSM12:29 pmDes Moines

May 6

DSM5:30 amDes Moines

9h 27m

2 stops

RSW3:57 pmFort Myers SW Florida Intl

$376

United Airlines

May 22

RSW4:38 pmFort Myers SW Florida Intl

5h 34m

1 stop

DSM9:12 pmDes Moines

May 26

DSM6:00 amDes Moines

7h 44m

1 stop

RSW2:44 pmFort Myers SW Florida Intl

$407

American Airlines flights from Fort Myers to Des Moines

Our best American Airlines deals on Fort Myers to Des Moines flight tickets

American Airlines

Feb 26

RSW5:27 pmFort Myers SW Florida Intl

7h 21m

1 stop

DSM11:48 pmDes Moines

Mar 5

DSM2:02 pmDes Moines

5h 40m

1 stop

RSW8:42 pmFort Myers SW Florida Intl

$417

American Airlines

Feb 26

RSW6:23 pmFort Myers SW Florida Intl

6h 17m

1 stop

DSM11:40 pmDes Moines

Mar 5

DSM5:00 amDes Moines

6h 18m

1 stop

RSW12:18 pmFort Myers SW Florida Intl

$427

American Airlines

Feb 26

RSW6:23 pmFort Myers SW Florida Intl

6h 17m

1 stop

DSM11:40 pmDes Moines

Mar 5

DSM5:00 amDes Moines

7h 04m

2 stops

RSW1:04 pmFort Myers SW Florida Intl

$433

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

lun 4/6

10:54 am-1:13 pm

Nonstop3h 19m

Des Moines

ven 4/10

6:00 am-10:04 am

Nonstop3h 04m

$308

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

ven 4/10

7:01 am-12:29 pm

1 stop6h 28m

Des Moines

mer 5/6

6:15 am-2:37 pm

1 stop7h 22m

$371

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

ven 4/10

7:01 am-12:29 pm

1 stop6h 28m

Des Moines

mer 5/6

5:30 am-3:57 pm

2 stops9h 27m

$376

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

ven 5/22

4:38 pm-9:12 pm

1 stop5h 34m

Des Moines

mar 5/26

6:00 am-2:44 pm

1 stop7h 44m

$407

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

gio 2/26

5:27 pm-11:48 pm

1 stop7h 21m

Des Moines

gio 3/5

2:02 pm-8:42 pm

1 stop5h 40m

$417

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

lun 4/6

10:54 am-1:13 pm

Nonstop3h 19m

Des Moines

ven 4/10

8:14 pm-10:37 am

2 stops37h 23m

$423

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

gio 2/26

6:23 pm-11:40 pm

1 stop6h 17m

Des Moines

gio 3/5

5:00 am-12:18 pm

1 stop6h 18m

$427

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

gio 2/26

6:23 pm-11:40 pm

1 stop6h 17m

Des Moines

gio 3/5

5:00 am-1:04 pm

2 stops7h 04m

$433

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

ven 5/22

12:55 pm-11:05 pm

2 stops11h 10m

Des Moines

mar 5/26

5:30 am-12:45 pm

1 stop6h 15m

$438

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

gio 2/26

6:00 am-1:17 pm

1 stop8h 17m

Des Moines

gio 3/5

5:00 am-1:04 pm

2 stops7h 04m

$440

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Fort Myers to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then January is your next best option. Flight prices from Fort Myers to Des Moines during January average around $200.

What is the cheapest Fort Myers SW Florida Intl to Des Moines flight route?

Fly from Fort Myers SW Florida Intl to Des Moines for the best Fort Myers SW Florida Intl - Des Moines flight prices

What cabin class options are available on Fort Myers SW Florida Intl to Des Moines flights?

There is only 1 cabin class available to choose from on Fort Myers SW Florida Intl to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Fort Myers to Des Moines flights?

You could potentially save up to 4% on your flight if you consider stops on a Fort Myers to Des Moines flight.

How have Fort Myers to Des Moines flight prices changed over time?

When to book flights from Fort Myers to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Fort Myers to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Fort Myers to Des Moines (RSW to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Des Moines

Fastest flight time	3h 19m
Direct flights	Tue and Sat
Airports in Des Moines	1 airport

The fastest flight from Fort Myers to Des Moines takes 3h 19m

Direct flights go from Fort Myers to Des Moines on Tuesday and Saturday. The only airline offering direct flights is Allegiant Air.

There is 1 airport in Des Moines. From Fort Myers there are direct flights to Des Moines (DSM).

Search flight deals

How far is Fort Myers SW Florida Intl to Des Moines by plane?
A flight from Fort Myers SW Florida Intl to Des Moines will travel around 1228.7 mi. Typically, this will take 3h 19m by plane in normal conditions.
When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?
Prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?
As of February 2026, there are 2 operators available to choose from for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport.
How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Fort Myers SW Florida Intl Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Fort Myers to Des Moines?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Fort Myers to Des Moines is Airbus A320-100/200 (100.00% of total bookings).
What is the most popular airline from Fort Myers to Des Moines?
Based on momondo bookings for flights between Fort Myers and Des Moines, the leading airline is American Airlines, making up 52% of the total bookings. Other popular airlines include Southwest with 48%.

Best airlines flying from Fort Myers to Des Moines

Compare and see reviews for airlines that fly from Fort Myers to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.2 11,238 reviews		Search American Airlines flights
Southwest	PriceFrom $346	Free Cancellation	Rating 8.0 4,276 reviews		Search Southwest flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Pella

Newton

Johnston

Boone

Osceola

Norwalk

Oskaloosa

Grinnell

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to Des Moines?

It is quick and easy to find Fort Myers to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Fort Myers to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Fort Myers which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Fort Myers to Des Moines?

Once you have performed a search for Fort Myers to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Fort Myers to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Fort Myers to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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Cheap flights from Fort Myers to Des Moines from $127

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to Des Moines departing on 2/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Fort Myers to Des Moines

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then January is your next best option. Flight prices from Fort Myers to Des Moines during January average around $200.

What is the cheapest Fort Myers SW Florida Intl to Des Moines flight route?

Fly from Fort Myers SW Florida Intl to Des Moines for the best Fort Myers SW Florida Intl - Des Moines flight prices

What cabin class options are available on Fort Myers SW Florida Intl to Des Moines flights?

There is only 1 cabin class available to choose from on Fort Myers SW Florida Intl to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Fort Myers to Des Moines flights?

You could potentially save up to 4% on your flight if you consider stops on a Fort Myers to Des Moines flight.

How have Fort Myers to Des Moines flight prices changed over time?

What is the cheapest airline that flies from Fort Myers SW Florida Intl to Des Moines?

Frontier, United Airlines, and American Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Des Moines

What airlines fly to Des Moines?

How many flights depart from Fort Myers to Des Moines on average per week?

The number of flights available between Fort Myers and Des Moines is 2 per week as of February 2026. The most frequent departure day is Mon, with 50% of weekly flights leaving on this day.

When to book flights from Fort Myers to Des Moines

Cheap Fort Myers to Des Moines (RSW to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Des Moines

Fastest flight time

Direct flights

Airports in Des Moines

How far is Fort Myers SW Florida Intl to Des Moines by plane?

When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular plane model from Fort Myers to Des Moines?

What is the most popular airline from Fort Myers to Des Moines?

Best airlines flying from Fort Myers to Des Moines

Compare and see reviews for airlines that fly from Fort Myers to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to Des Moines?

Can I find flights from Fort Myers to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from Fort Myers to Des Moines?

I’m not ready to book a flight from Fort Myers to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa

Fly your favorite airline to Des Moines

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Des Moines

List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

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