What airlines fly to Des Moines?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Des Moines from Fort Myers according to our data. Allegiant Air is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 3 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Fort Myers SW Florida Intl to Des Moines?

Allegiant Air, American Airlines, and Southwest are the most popular carriers operating from Fort Myers SW Florida Intl to Des Moines

When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

Prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

As of November 2026, there are 3 operators available to choose from for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport.

How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Fort Myers SW Florida Intl Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$38 Cheap Flights from Fort Myers to Des Moines in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Fort Myers to Des Moines

Round-trip

One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

7:53 pm - 10:21 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

3h 28mnonstop

3:05 pm - 7:03 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

2h 58mnonstop

$86Allegiant Air

Fri, Dec 4 - Mon, Dec 7

7:53 pm - 10:21 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

3h 28mnonstop

3:05 pm - 7:03 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

2h 58mnonstop

$89Allegiant Air

Fri, Dec 4 - Mon, Dec 7

10:45 am - 1:07 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

3h 22mnonstop

6:00 am - 9:55 amDSM Des Moines-RSW Fort Myers SW Florida Intl

2h 55mnonstop

$96Allegiant Air

Fri, Jan 8 - Mon, Jan 11

7:53 pm - 10:21 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

3h 28mnonstop

2:50 pm - 8:46 amDSM Des Moines-RSW Fort Myers SW Florida Intl

40h 56m2 stops Tampa St. Petersburg Charleston

$241Multiple Airlines

Fri, Dec 4 - Mon, Dec 7

10:45 am - 1:07 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

3h 22mnonstop

11:12 am - 8:10 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

55h 58m3 stops Nashville Intl Orlando Detroit Metropolitan Wayne County

$264Multiple Airlines

Fri, Jan 8 - Mon, Jan 11

7:00 am - 12:09 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

30h 09m3 stops Raleigh-Durham Atlanta Hartsfield-Jackson Orlando

3:05 pm - 7:03 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

2h 58mnonstop

$297Multiple Airlines

Fri, Dec 4 - Mon, Dec 7

10:12 am - 5:19 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

8h 07m1 stop Detroit Metropolitan Wayne County

5:22 pm - 12:35 amDSM Des Moines-RSW Fort Myers SW Florida Intl

6h 13m1 stop Atlanta Hartsfield-Jackson

$363Delta

Wed, Jan 13 - Tue, Jan 19

4:28 pm - 12:26 amRSW Fort Myers SW Florida Intl-DSM Des Moines

8h 58m1 stop Chicago O'Hare Intl

8:07 am - 2:07 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

5h 00m1 stop Charlotte Douglas

$373American Airlines

Wed, Jan 13 - Tue, Jan 19

10:12 am - 5:19 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

8h 07m1 stop Detroit Metropolitan Wayne County

5:22 pm - 12:35 amDSM Des Moines-RSW Fort Myers SW Florida Intl

6h 13m1 stop Atlanta Hartsfield-Jackson

$373Delta

Wed, Jan 13 - Tue, Jan 19

11:11 am - 7:13 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

9h 02m2 stops Charlotte Douglas Chicago O'Hare Intl

2:39 pm - 11:16 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

7h 37m1 stop Chicago O'Hare Intl

$374American Airlines

Wed, Jan 13 - Tue, Jan 19

Cheap last minute flights

Enter your travel dates to find the best prices.

6:26 pm - 12:10 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

18h 44m2 stops New Orleans Louis Armstrong Las Vegas Harry Reid Intl

2:41 pm - 6:40 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

2h 59mnonstop

$771Multiple Airlines

Sat, Nov 14 - Mon, Nov 16

9:31 am - 12:10 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

27h 39m1 stop Las Vegas Harry Reid Intl

2:41 pm - 6:40 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

2h 59mnonstop

$833Multiple Airlines

Sat, Nov 14 - Mon, Nov 16

8:15 am - 7:46 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

36h 31m3 stops Greater Rochester Intl Tampa Fort Lauderdale

2:41 pm - 6:40 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

2h 59mnonstop

$859Multiple Airlines

Sat, Nov 14 - Mon, Nov 16

12:20 pm - 10:36 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

11h 16m1 stop Washington, D.C. Reagan-National

7:06 am - 11:17 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

15h 11m1 stop Charlotte Douglas

$999American Airlines

Wed, Nov 18 - Tue, Nov 24

6:00 am - 2:26 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

9h 26m2 stops Newark Chicago O'Hare Intl

8:00 am - 2:49 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

5h 49m1 stop Chicago O'Hare Intl

$1,017United Airlines

Wed, Nov 18 - Tue, Nov 24

11:55 am - 8:50 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

9h 55m2 stops Lambert-St Louis Denver Intl

5:10 am - 1:20 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

7h 10m2 stops Chicago Midway Baltimore/Washington

$1,032Southwest

Wed, Nov 18 - Tue, Nov 24

7:00 am - 11:25 amRSW Fort Myers SW Florida Intl-DSM Des Moines

5h 25m1 stop Chicago Midway

3:30 pm - 10:20 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

5h 50m1 stop Chicago Midway

$1,097Southwest

Thu, Nov 19 - Thu, Nov 19

6:05 am - 2:15 pmRSW Fort Myers SW Florida Intl-DSM Des Moines

9h 10m2 stops Lambert-St Louis Denver Intl

3:30 pm - 10:20 pmDSM Des Moines-RSW Fort Myers SW Florida Intl

5h 50m1 stop Chicago Midway

$1,102Southwest

Thu, Nov 19 - Thu, Nov 19

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Allegiant Air flights from Fort Myers to Des Moines

Our best Allegiant Air deals on Fort Myers to Des Moines flight tickets

Allegiant Air

Dec 4

RSW7:53 pmFort Myers SW Florida Intl

3h 28m

DSM10:21 pmDes Moines

Dec 7

DSM3:05 pmDes Moines

2h 58m

RSW7:03 pmFort Myers SW Florida Intl

$86

Allegiant Air

Dec 4

RSW7:53 pmFort Myers SW Florida Intl

3h 28m

DSM10:21 pmDes Moines

Dec 7

DSM3:05 pmDes Moines

2h 58m

RSW7:03 pmFort Myers SW Florida Intl

$89

Allegiant Air

Jan 8

RSW10:45 amFort Myers SW Florida Intl

3h 22m

DSM1:07 pmDes Moines

Jan 11

DSM6:00 amDes Moines

2h 55m

RSW9:55 amFort Myers SW Florida Intl

$96

Delta flights from Fort Myers to Des Moines

Our best Delta deals on Fort Myers to Des Moines flight tickets

Delta

Jan 13

RSW10:12 amFort Myers SW Florida Intl

8h 07m

1 stop

DSM5:19 pmDes Moines

Jan 19

DSM5:22 pmDes Moines

6h 13m

1 stop

RSW12:35 amFort Myers SW Florida Intl

$363

Delta

Jan 13

RSW10:12 amFort Myers SW Florida Intl

8h 07m

1 stop

DSM5:19 pmDes Moines

Jan 19

DSM5:22 pmDes Moines

6h 13m

1 stop

RSW12:35 amFort Myers SW Florida Intl

$373

Delta

Dec 10

RSW2:45 pmFort Myers SW Florida Intl

7h 46m

1 stop

DSM9:31 pmDes Moines

Dec 17

DSM6:53 pmDes Moines

4h 49m

1 stop

RSW12:42 amFort Myers SW Florida Intl

$413

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Fri 12/4

7:53 pm-10:21 pm

Nonstop3h 28m

Des Moines

Mon 12/7

3:05 pm-7:03 pm

Nonstop2h 58m

$86

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Fri 12/4

7:53 pm-10:21 pm

Nonstop3h 28m

Des Moines

Mon 12/7

3:05 pm-7:03 pm

Nonstop2h 58m

$89

Quickest round-trip

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Fri 1/8

10:45 am-1:07 pm

Nonstop3h 22m

Des Moines

Mon 1/11

6:00 am-9:55 am

Nonstop2h 55m

$96

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Fri 12/4

7:53 pm-10:21 pm

Nonstop3h 28m

Des Moines

Mon 12/7

2:50 pm-8:46 am

2 stops40h 56m

$241

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Fri 1/8

10:45 am-1:07 pm

Nonstop3h 22m

Des Moines

Mon 1/11

11:12 am-8:10 pm

3 stops55h 58m

$264

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Fri 12/4

7:00 am-12:09 pm

3 stops30h 09m

Des Moines

Mon 12/7

3:05 pm-7:03 pm

Nonstop2h 58m

$297

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Wed 1/13

10:12 am-5:19 pm

1 stop8h 07m

Des Moines

Tue 1/19

5:22 pm-12:35 am

1 stop6h 13m

$363

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Wed 1/13

4:28 pm-12:26 am

1 stop8h 58m

Des Moines

Tue 1/19

8:07 am-2:07 pm

1 stop5h 00m

$373

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Wed 1/13

10:12 am-5:19 pm

1 stop8h 07m

Des Moines

Tue 1/19

5:22 pm-12:35 am

1 stop6h 13m

$373

Fort MyersDes Moines

RSW Fort Myers SW Florida Intl - DSM Des Moines

RSWDSM

Fort Myers SW Florida Intl

Wed 1/13

11:11 am-7:13 pm

2 stops9h 02m

Des Moines

Tue 1/19

2:39 pm-11:16 pm

1 stop7h 37m

$374

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Fort Myers to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then November is your next best option. Flight prices from Fort Myers to Des Moines during November average around $210.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Fort Myers to Des Moines is on a Friday. Travelers who choose to depart for Des Moines on a Friday will often find tickets for as low as $122. Flights from Fort Myers to Des Moines on a Monday will generally be more expensive and average around $255. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Fort Myers to Des Moines in the evening for as low as $117. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $491. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Fort Myers SW Florida Intl to Des Moines flight route?

Fly from Fort Myers SW Florida Intl to Des Moines for the best Fort Myers SW Florida Intl - Des Moines flight prices

What cabin class options are available on Fort Myers to Des Moines flights?

There is only 1 cabin class available to choose from on Fort Myers to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Fort Myers to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Fort Myers to Des Moines.

How have Fort Myers to Des Moines flight prices changed over time?

As of November 2026, prices for Fort Myers to Des Moines flights are approximately 66% cheaper when compared to flights at the same time last year.

When to book flights from Fort Myers to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Fort Myers to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Fort Myers to Des Moines (RSW to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Des Moines

Best Price Found	$38
Fastest flight time	3h 13m
Direct flights	Tue and Sat
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from Fort Myers in the past 72 hours is $38. The best round-trip flight deal from Fort Myers to Des Moines found on momondo in the last 72 hours is $86.

The fastest flight from Fort Myers to Des Moines takes 3h 13m

Direct flights go from Fort Myers to Des Moines on Tuesday and Saturday. The only airline offering direct flights is Allegiant Air.

There is 1 airport in Des Moines. From Fort Myers there are direct flights to Des Moines (DSM).

Search flight deals

Frequently asked questions about flying from Fort Myers to Des Moines

How far is Fort Myers SW Florida Intl to Des Moines by plane?
A flight from Fort Myers SW Florida Intl to Des Moines will travel around 1228.7 mi. Typically, this will take 3h 13m by plane in normal conditions.
When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?
Prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?
As of November 2026, there are 3 operators available to choose from for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport.
How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Fort Myers SW Florida Intl Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Fort Myers to Des Moines?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Fort Myers to Des Moines is Airbus A320-100/200 (88.89% of total bookings). The next most popular plane model is Airbus A319 (11.11%).
What is the most popular airline from Fort Myers to Des Moines?
Based on momondo bookings for flights between Fort Myers and Des Moines, the leading airline is Allegiant Air, making up 37% of the total bookings. Other popular airlines include American Airlines with 35% and Delta with 28%.

Best airlines flying from Fort Myers to Des Moines

Compare and see reviews for airlines that fly from Fort Myers to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $96	Free Cancellation	Rating 7.3 676 reviews	Search Allegiant Air flights
Delta	PriceFrom $152	Free Cancellation	Rating 7.8 8,716 reviews	Search Delta flights
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.0 12,234 reviews	Search American Airlines flights

West Des Moines

Ames

Ankeny

Clive

Altoona

Pella

Osceola

Urbandale

Johnston

Boone

Newton

Oskaloosa

Grinnell

Norwalk

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to Des Moines?

It is quick and easy to find Fort Myers to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Fort Myers to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Fort Myers which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Fort Myers to Des Moines?

Once you have performed a search for Fort Myers to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Fort Myers to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Fort Myers to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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Cheap flights from Fort Myers to Des Moines from $38

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to Des Moines departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Allegiant Air flights from Fort Myers to Des Moines

Our best Allegiant Air deals on Fort Myers to Des Moines flight tickets

Delta flights from Fort Myers to Des Moines

Our best Delta deals on Fort Myers to Des Moines flight tickets

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How to get the cheapest flight ticket from Fort Myers to Des Moines

What is the cheapest month to fly to Des Moines?

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest Fort Myers SW Florida Intl to Des Moines flight route?

What cabin class options are available on Fort Myers to Des Moines flights?

Can stopping save me money on Fort Myers to Des Moines flights?

How have Fort Myers to Des Moines flight prices changed over time?

What is the cheapest airline that flies from Fort Myers SW Florida Intl to Des Moines?

What airlines fly to Des Moines?

When to book flights from Fort Myers to Des Moines

Cheap Fort Myers to Des Moines (RSW to DSM) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in Des Moines

Frequently asked questions about flying from Fort Myers to Des Moines

Best airlines flying from Fort Myers to Des Moines

Compare and see reviews for airlines that fly from Fort Myers to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa

Fly your favorite airline to Des Moines

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Des Moines

List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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