Cheap flights from Fort Myers to Des Moines from $159
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to Des Moines departing on 11/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Find the cheapest flights from Fort Myers to Des Moines
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
American Airlines flights from Fort Myers to Des Moines
Our best American Airlines deals on Fort Myers to Des Moines flight tickets
United Airlines flights from Fort Myers to Des Moines
Our best United Airlines deals on Fort Myers to Des Moines flight tickets
See travel insights to Des Moines from
How to get the cheapest flight ticket from Fort Myers to Des Moines
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Des Moines?
If you’re not able to fly to Des Moines in February, then March is your next best option. Flight prices from Fort Myers to Des Moines during March average around $366.
What is the cheapest day to depart on your flight to Des Moines?
The cheapest day to depart from Fort Myers to Des Moines is on a Friday. Travelers who choose to depart for Des Moines on a Friday will often find tickets for as low as $396. Flights from Fort Myers to Des Moines on a Monday will generally be more expensive and average around $487. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.
What is the cheapest time of day to depart on your flight to Des Moines?
According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Fort Myers to Des Moines at noon for as low as $407. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $503. Of course, these prices can vary depending on the time of year and what airport you fly to.
How have Fort Myers to Des Moines flight prices changed over time?
As of June 2025, prices for Fort Myers to Des Moines flights are approximately 37% cheaper when compared to flights at the same time last year.
What is the cheapest airline that flies from Fort Myers SW Florida Intl to Des Moines?
American Airlines and United Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Des Moines
What airlines fly to Des Moines?
Delta, Southwest and Allegiant Air are the top three most popular airlines that fly to Des Moines from Fort Myers according to our data. Delta is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.
When to book flights from Fort Myers to Des Moines
Cheap Fort Myers to Des Moines (RSW to DSM) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Des Moines
How far is Fort Myers SW Florida Intl to Des Moines by plane?
A flight from Fort Myers SW Florida Intl to Des Moines will travel around 1228.7 mi. Typically, this will take 4h 25m by plane in normal conditions.
When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?
Prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?
As of June 2025, there are 3 operators available to choose from for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport.
How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Fort Myers SW Florida Intl Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Fort Myers to Des Moines?
Based on momondo bookings for flights between Fort Myers and Des Moines, the leading airline is Southwest, making up 47% of the total bookings. Other popular airlines include Delta with 33% and American Airlines with 20%.
Best airlines flying from Fort Myers to Des Moines
Compare and see reviews for airlines that fly from Fort Myers to Des Moines with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $276 | Free Cancellation | Rating 8.0 7,950 reviews | |||
| PriceFrom $286 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $366 | Free Cancellation | Rating 8.0 4,287 reviews |
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Fort Myers to Des Moines?
It is quick and easy to find Fort Myers to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.
Can I find flights from Fort Myers to Des Moines with flexible booking policies on momondo?
momondo does allow users to show only those flights to Des Moines from Fort Myers which offer a flexible booking policy as well as other useful filters and features.
How can momondo help me find flights from Fort Myers to Des Moines?
Once you have performed a search for Fort Myers to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.
I’m not ready to book a flight from Fort Myers to Des Moines right now. Can momondo alert me if prices change?
If you are not ready to book a flight from Fort Myers to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.