What airlines fly to Des Moines?

Delta, Southwest and Allegiant Air are the top three most popular airlines that fly to Des Moines from Fort Myers according to our data. Delta is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Fort Myers SW Florida Intl to Des Moines?

Allegiant Air, American Airlines, and United Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Des Moines

When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

Prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

As of July 2025, there are 3 operators available to choose from for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport.

How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Fort Myers SW Florida Intl Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$112 Cheap Flights from Fort Myers to Des Moines in 2025

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Find the cheapest flights from Fort Myers to Des Moines

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

7:02 pm - 9:21 pmRSW-DSM

3h 19mnonstop

2:08 pm - 6:12 pmDSM-RSW

3h 04mnonstop

$195Allegiant Air

Find Deal

Mon, Jan 19 - Mon, Jan 26

3:45 pm - 11:56 pmRSW-DSM

9h 11m1 stop

8:00 am - 2:43 pmDSM-RSW

5h 43m1 stop

$292United Airlines

Find Deal

Mon, Sep 29 - Tue, Sep 30

2:13 pm - 8:35 pmRSW-DSM

7h 22m1 stop

2:40 pm - 11:39 pmDSM-RSW

7h 59m1 stop

$297Delta

Find Deal

Thu, Oct 16 - Mon, Oct 20

11:48 am - 4:44 pmRSW-DSM

5h 56m1 stop

5:00 am - 3:43 pmDSM-RSW

9h 43m2 stops

$302American Airlines

Find Deal

Fri, Aug 29 - Fri, Sep 5

4:35 pm - 11:28 pmRSW-DSM

7h 53m2 stops

7:03 am - 3:43 pmDSM-RSW

7h 40m2 stops

$307American Airlines

Find Deal

Mon, Sep 29 - Wed, Oct 1

7:50 pm - 11:30 pmRSW-DSM

4h 40m1 stop

6:35 am - 8:45 pmDSM-RSW

13h 10m2 stops

$323Southwest

Find Deal

Thu, Oct 16 - Mon, Oct 20

7:50 pm - 11:30 pmRSW-DSM

4h 40m1 stop

6:35 am - 8:45 pmDSM-RSW

13h 10m2 stops

$338Southwest

Find Deal

Fri, Oct 17 - Mon, Oct 20

6:25 am - 11:35 amRSW-DSM

6h 10m1 stop

5:15 pm - 12:22 amDSM-RSW

6h 07m1 stop

$387Delta

Find Deal

Sat, Dec 20 - Sat, Jan 3

6:00 am - 8:09 pmRSW-DSM

15h 09m2 stops

2:22 pm - 3:56 pmDSM-RSW

24h 34m3 stops

$443

Find Deal

Fri, Aug 29 - Fri, Sep 5

7:00 am - 8:09 pmRSW-DSM

14h 09m3 stops

2:22 pm - 3:56 pmDSM-RSW

24h 34m3 stops

$554

Find Deal

Fri, Aug 29 - Fri, Sep 5

United Airlines flights from Fort Myers to Des Moines

Our best United Airlines deals on Fort Myers to Des Moines flight tickets

United Airlines

Sep 29

RSW3:45 pmFort Myers SW Florida Intl

9h 11m

1 stop

DSM11:56 pmDes Moines

Sep 30

DSM8:00 amDes Moines

5h 43m

1 stop

RSW2:43 pmFort Myers SW Florida Intl

$292

Find similar

United Airlines

Sep 29

RSW9:10 amFort Myers SW Florida Intl

15h 46m

3 stops

DSM11:56 pmDes Moines

Sep 30

DSM6:00 amDes Moines

11h 08m

2 stops

RSW6:08 pmFort Myers SW Florida Intl

$407

Find similar

United Airlines

Dec 20

RSW12:27 pmFort Myers SW Florida Intl

6h 38m

1 stop

DSM6:05 pmDes Moines

Jan 3

DSM6:46 pmDes Moines

14h 54m

2 stops

RSW10:40 amFort Myers SW Florida Intl

$512

Find similar

Southwest flights from Fort Myers to Des Moines

Our best Southwest deals on Fort Myers to Des Moines flight tickets

Southwest

Oct 16

RSW7:50 pmFort Myers SW Florida Intl

4h 40m

1 stop

DSM11:30 pmDes Moines

Oct 20

DSM6:35 amDes Moines

13h 10m

2 stops

RSW8:45 pmFort Myers SW Florida Intl

$323

Find similar

Southwest

Oct 17

RSW7:50 pmFort Myers SW Florida Intl

4h 40m

1 stop

DSM11:30 pmDes Moines

Oct 20

DSM6:35 amDes Moines

13h 10m

2 stops

RSW8:45 pmFort Myers SW Florida Intl

$338

Find similar

Southwest

Oct 10

RSW2:55 pmFort Myers SW Florida Intl

9h 35m

2 stops

DSM11:30 pmDes Moines

Oct 13

DSM5:35 amDes Moines

10h 35m

2 stops

RSW5:10 pmFort Myers SW Florida Intl

$447

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 1/19

7:02 pm-9:21 pm

Nonstop3h 19m

Des Moines

Mon 1/26

2:08 pm-6:12 pm

Nonstop3h 04m

$195

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 9/29

3:45 pm-11:56 pm

1 stop9h 11m

Des Moines

Tue 9/30

8:00 am-2:43 pm

1 stop5h 43m

$292

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Thu 10/16

2:13 pm-8:35 pm

1 stop7h 22m

Des Moines

Mon 10/20

2:40 pm-11:39 pm

1 stop7h 59m

$297

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Fri 8/29

11:48 am-4:44 pm

1 stop5h 56m

Des Moines

Fri 9/5

5:00 am-3:43 pm

2 stops9h 43m

$302

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 9/29

4:35 pm-11:28 pm

2 stops7h 53m

Des Moines

Wed 10/1

7:03 am-3:43 pm

2 stops7h 40m

$307

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Thu 10/16

7:50 pm-11:30 pm

1 stop4h 40m

Des Moines

Mon 10/20

6:35 am-8:45 pm

2 stops13h 10m

$323

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Fri 10/17

7:50 pm-11:30 pm

1 stop4h 40m

Des Moines

Mon 10/20

6:35 am-8:45 pm

2 stops13h 10m

$338

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Sat 12/20

6:25 am-11:35 am

1 stop6h 10m

Des Moines

Sat 1/3

5:15 pm-12:22 am

1 stop6h 07m

$387

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Fri 8/29

6:00 am-8:09 pm

2 stops15h 09m

Des Moines

Fri 9/5

2:22 pm-3:56 pm

3 stops24h 34m

$443

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Fri 8/29

7:00 am-8:09 pm

3 stops14h 09m

Des Moines

Fri 9/5

2:22 pm-3:56 pm

3 stops24h 34m

$554

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Fort Myers to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in August, then February is your next best option. Flight prices from Fort Myers to Des Moines during February average around $351.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Fort Myers to Des Moines is on a Friday. Travelers who choose to depart for Des Moines on a Friday will often find tickets for as low as $396. Flights from Fort Myers to Des Moines on a Monday will generally be more expensive and average around $487. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Fort Myers to Des Moines at noon for as low as $407. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $503. Of course, these prices can vary depending on the time of year and what airport you fly to.

How have Fort Myers to Des Moines flight prices changed over time?

When to book flights from Fort Myers to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Fort Myers to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Fort Myers to Des Moines (RSW to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Des Moines

Best Price Found	$112
Fastest flight time	3h 19m
Direct flights	Tue and Sat
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from Fort Myers in the past 72 hours is $112. The best round-trip flight deal from Fort Myers to Des Moines found on momondo in the last 72 hours is $195.

The fastest flight from Fort Myers to Des Moines takes 3h 19m

Direct flights go from Fort Myers to Des Moines on Tuesday and Saturday. The only airline offering direct flights is Allegiant Air.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

How far is Fort Myers SW Florida Intl to Des Moines by plane?
A flight from Fort Myers SW Florida Intl to Des Moines will travel around 1228.7 mi. Typically, this will take 3h 19m by plane in normal conditions.
When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?
Prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?
As of July 2025, there are 3 operators available to choose from for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport.
How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Fort Myers SW Florida Intl Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Fort Myers to Des Moines?
Based on momondo bookings for flights between Fort Myers and Des Moines, the leading airline is Southwest, making up 48% of the total bookings. Other popular airlines include American Airlines with 26% and Delta with 26%.

Best airlines flying from Fort Myers to Des Moines

Compare and see reviews for airlines that fly from Fort Myers to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $276	Free Cancellation	Rating 8.0 7,981 reviews	Search Delta flights
American Airlines	PriceFrom $284	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Southwest	PriceFrom $366	Free Cancellation	Rating 8.0 4,246 reviews	Search Southwest flights

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Newton

Pella

Boone

Johnston

Osceola

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to Des Moines?

It is quick and easy to find Fort Myers to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Fort Myers to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Fort Myers which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Fort Myers to Des Moines?

Once you have performed a search for Fort Myers to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Fort Myers to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Fort Myers to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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Cheap flights from Fort Myers to Des Moines from $112

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to Des Moines departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Find the cheapest flights from Fort Myers to Des Moines

Cheap round-trip flights

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United Airlines flights from Fort Myers to Des Moines

Our best United Airlines deals on Fort Myers to Des Moines flight tickets

Southwest flights from Fort Myers to Des Moines

Our best Southwest deals on Fort Myers to Des Moines flight tickets

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Use the filters below to find and compare flights from Fort Myers to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from Fort Myers to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in August, then February is your next best option. Flight prices from Fort Myers to Des Moines during February average around $351.

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

How have Fort Myers to Des Moines flight prices changed over time?

What is the cheapest airline that flies from Fort Myers SW Florida Intl to Des Moines?

Allegiant Air, American Airlines, and United Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Des Moines

What airlines fly to Des Moines?

When to book flights from Fort Myers to Des Moines

Cheap Fort Myers to Des Moines (RSW to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Des Moines

Best Price Found

Fastest flight time

Direct flights

Airports in Des Moines

How far is Fort Myers SW Florida Intl to Des Moines by plane?

When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to Des Moines Airport?

How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular airline from Fort Myers to Des Moines?

Best airlines flying from Fort Myers to Des Moines

Compare and see reviews for airlines that fly from Fort Myers to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to Des Moines?

Can I find flights from Fort Myers to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from Fort Myers to Des Moines?

I’m not ready to book a flight from Fort Myers to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa