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Cheap flights from Florence, South Carolina to Boston from $530

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to Boston departing on 4/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:13 am - 11:55 amFLO-MHT
6h 42m2 stops
American Airlines Logo
5:48 am - 10:02 amMHT-FLO
4h 14m1 stop
$530American Airlines
Find Deal
Sat, Apr 4 - Wed, Apr 8
American Airlines Logo
5:13 am - 2:57 pmFLO-MHT
9h 44m2 stops
American Airlines Logo
5:47 am - 2:10 pmMHT-FLO
8h 23m2 stops
$543American Airlines
Find Deal
Sat, Apr 4 - Wed, Apr 8
American Airlines Logo
11:09 am - 4:42 pmFLO-MHT
5h 33m1 stop
American Airlines Logo
5:48 am - 10:02 amMHT-FLO
4h 14m1 stop
$617American Airlines
Find Deal
Sat, Apr 4 - Wed, Apr 8

American Airlines flights from Florence, South Carolina to Manchester, New Hampshire

Our best American Airlines deals on Florence, South Carolina to Manchester, New Hampshire flight tickets
American Airlines
Apr 4
FLO5:13 amFlorence
6h 42m
2 stops
MHT11:55 amManchester
Apr 8
MHT5:48 amManchester
4h 14m
1 stop
FLO10:02 amFlorence
$530
Find similar
American Airlines
Apr 4
FLO5:13 amFlorence
9h 44m
2 stops
MHT2:57 pmManchester
Apr 8
MHT5:47 amManchester
8h 23m
2 stops
FLO2:10 pmFlorence
$543
Find similar
American Airlines
Apr 4
FLO11:09 amFlorence
5h 33m
1 stop
MHT4:42 pmManchester
Apr 8
MHT5:48 amManchester
4h 14m
1 stop
FLO10:02 amFlorence
$617
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to Manchester, New Hampshire that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 9, 2025.
Use the filters below to find and compare flights from Florence, South Carolina to Manchester, New Hampshire that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceManchester

FLO - MHT

FLOMHT

Florence

Sat 4/4

5:13 am-11:55 am

2 stops6h 42m

Manchester

Wed 4/8

5:48 am-10:02 am

1 stop4h 14m

$530

FlorenceManchester

FLO - MHT

FLOMHT

Florence

Sat 4/4

5:13 am-2:57 pm

2 stops9h 44m

Manchester

Wed 4/8

5:47 am-2:10 pm

2 stops8h 23m

$543

FlorenceManchester

FLO - MHT

FLOMHT

Florence

Sat 4/4

11:09 am-4:42 pm

1 stop5h 33m

Manchester

Wed 4/8

5:48 am-10:02 am

1 stop4h 14m

$617

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Florence, South Carolina to Manchester, New Hampshire

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Manchester, New Hampshire?

Our most recent data shows that the best time of day to fly to Manchester, New Hampshire is in the morning. Flights from Florence, South Carolina to Manchester, New Hampshire during this time can be as low as $524. Flights at noon are often more expensive with an average ticket price of $621.

When to book flights from Florence, South Carolina to Manchester, New Hampshire

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to Manchester, New Hampshire according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Florence, South Carolina to Manchester, New Hampshire (FLO to MHT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Manchester, New Hampshire

Direct flights

None
There are no direct flights from Florence, South Carolina to Manchester, New Hampshire. There are no popular flight routes from Florence, South Carolina to Manchester, New Hampshire.
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  • How far is Florence to Manchester by plane?

    There are 754.2 mi between Florence and Manchester. Typically, this will take 5h 33m by plane in normal conditions.

  • When did momondo last update prices for flights from Florence Airport to Manchester Airport?

    Prices for flights from Florence Airport to Manchester Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Florence Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Florence Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Boston?

Book flights to Boston if you plan to visit one of these locations
Keene

Why use momondo?

Why should I use momondo to find a flight deal from Florence to Manchester?

It is quick and easy to find Florence to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Florence to Manchester with flexible booking policies on momondo?

All flight searches from Florence to Manchester on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Florence to Manchester?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Manchester from Florence.

I’m not ready to book a flight from Florence to Manchester right now. Can momondo alert me if prices change?

Price alerts on flights to Manchester from Florence are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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