Cheap flights from District of Columbia to Greenville from $89

The month of December is another great option to travel to Greenville, with average flight prices from District of Columbia averaging around $289.

According to our data, Saturday is the cheapest day to fly to Greenville from District of Columbia. The lowest ticket price found for a Saturday departure recently was $298. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $415. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

Our most recent data shows that the best time of day to fly to Greenville is in the evening. Flights from District of Columbia to Greenville during this time can be as low as $335. Flights to Greenville are more costly in the afternoon, with an average ticket price of $390. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Baltimore/Washington to Greenville for the best District of Columbia - Greenville flight prices

There are 4 cabin classes available to choose from on District of Columbia to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 36% on your flight if you consider stops on a District of Columbia to Greenville flight.

United Airlines, Delta, and Southwest are the most popular carriers operating from District of Columbia to Greenville

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Greenville from District of Columbia according to our data. American Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 7 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

As of July 2026, 11 flights take off from District of Columbia and land in Greenville each day. The most common flight departure time for this route is 5:00PM, with 64% of daily flights taking off in the afternoon.

As of July 2026, there are 82 flights per week flying from District of Columbia to Greenville. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.