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Cheap flights from Detroit to St. Louis from $55

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to St. Louis departing on 1/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:29 pm - 11:01 pmDTW-STL
5h 32m1 stop
Frontier Logo
4:13 pm - 10:31 amSTL-DTW
17h 18m1 stop
$136Frontier
Find Deal
Wed, Nov 19 - Fri, Nov 21
Multiple Airlines Logo
5:50 am - 11:07 amDTW-STL
6h 17m1 stop
Multiple Airlines Logo
12:04 pm - 7:52 pmSTL-DTW
6h 48m1 stop
$152Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Frontier Logo
9:18 am - 10:33 pmDTW-STL
14h 15m1 stop
Frontier Logo
3:30 pm - 8:20 amSTL-DTW
15h 50m1 stop
$159Frontier
Find Deal
Mon, Dec 8 - Thu, Dec 11
Frontier Logo
6:12 pm - 8:59 amDTW-STL
15h 47m1 stop
Frontier Logo
7:43 pm - 4:19 pmSTL-DTW
19h 36m1 stop
$164Frontier
Find Deal
Thu, Dec 4 - Sat, Dec 6
Multiple Airlines Logo
6:59 pm - 11:07 amDTW-STL
17h 08m1 stop
Multiple Airlines Logo
7:43 pm - 4:19 pmSTL-DTW
19h 36m1 stop
$173Multiple Airlines
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Wed, Dec 3 - Sat, Dec 6
Frontier Logo
5:14 pm - 9:07 amDTW-STL
16h 53m1 stop
Frontier Logo
7:43 pm - 11:43 amSTL-DTW
15h 00m1 stop
$176Frontier
Find Deal
Mon, Nov 17 - Mon, Nov 24
Frontier Logo
5:14 pm - 9:07 amDTW-STL
16h 53m1 stop
Frontier Logo
4:13 pm - 10:31 amSTL-DTW
17h 18m1 stop
$179Frontier
Find Deal
Mon, Nov 17 - Fri, Nov 21
Frontier Logo
5:20 pm - 10:14 amDTW-STL
17h 54m1 stop
Frontier Logo
7:43 pm - 11:52 amSTL-DTW
15h 09m2 stops
$182Frontier
Find Deal
Fri, Dec 5 - Sat, Dec 6
United Airlines Logo
11:05 am - 3:40 pmDTW-STL
5h 35m1 stop
United Airlines Logo
11:50 am - 6:06 pmSTL-DTW
5h 16m1 stop
$251United Airlines
Find Deal
Wed, Dec 3 - Tue, Dec 9
United Airlines Logo
6:00 am - 3:40 pmDTW-STL
10h 40m2 stops
United Airlines Logo
8:00 am - 1:06 pmSTL-DTW
4h 06m1 stop
$256United Airlines
Find Deal
Thu, Dec 4 - Sat, Dec 6

Frontier flights from Detroit to St. Louis

Our best Frontier deals on Detroit to St. Louis flight tickets
Frontier
Nov 19
DTW6:29 pmDetroit Metropolitan Wayne County
5h 32m
1 stop
STL11:01 pmLambert-St Louis
Nov 21
STL4:13 pmLambert-St Louis
17h 18m
1 stop
DTW10:31 amDetroit Metropolitan Wayne County
$136
Find similar
Frontier
Dec 8
DTW9:18 amDetroit Metropolitan Wayne County
14h 15m
1 stop
STL10:33 pmLambert-St Louis
Dec 11
STL3:30 pmLambert-St Louis
15h 50m
1 stop
DTW8:20 amDetroit Metropolitan Wayne County
$159
Find similar
Frontier
Dec 4
DTW6:12 pmDetroit Metropolitan Wayne County
15h 47m
1 stop
STL8:59 amLambert-St Louis
Dec 6
STL7:43 pmLambert-St Louis
19h 36m
1 stop
DTW4:19 pmDetroit Metropolitan Wayne County
$164
Find similar

Spirit Airlines flights from Detroit to St. Louis

Our best Spirit Airlines deals on Detroit to St. Louis flight tickets
Spirit Airlines
Nov 19
DTW3:12 pmDetroit Metropolitan Wayne County
19h 46m
2 stops
STL9:58 amLambert-St Louis
Nov 23
STL11:08 amLambert-St Louis
30h 33m
3 stops
DTW6:41 pmDetroit Metropolitan Wayne County
$301
Find similar
Spirit Airlines
Nov 19
DTW8:05 pmDetroit Metropolitan Wayne County
14h 53m
1 stop
STL9:58 amLambert-St Louis
Nov 23
STL11:08 amLambert-St Louis
30h 33m
3 stops
DTW6:41 pmDetroit Metropolitan Wayne County
$313
Find similar
Spirit Airlines
Nov 19
DTW7:00 amDetroit Metropolitan Wayne County
27h 58m
3 stops
STL9:58 amLambert-St Louis
Nov 23
STL11:08 amLambert-St Louis
28h 54m
3 stops
DTW5:02 pmDetroit Metropolitan Wayne County
$381
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Detroit to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 11/19

6:29 pm-11:01 pm

1 stop5h 32m

Lambert-St Louis

Fri 11/21

4:13 pm-10:31 am

1 stop17h 18m

$136

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Thu 12/4

5:50 am-11:07 am

1 stop6h 17m

Lambert-St Louis

Thu 12/11

12:04 pm-7:52 pm

1 stop6h 48m

$152

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 12/8

9:18 am-10:33 pm

1 stop14h 15m

Lambert-St Louis

Thu 12/11

3:30 pm-8:20 am

1 stop15h 50m

$159

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Thu 12/4

6:12 pm-8:59 am

1 stop15h 47m

Lambert-St Louis

Sat 12/6

7:43 pm-4:19 pm

1 stop19h 36m

$164

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 12/3

6:59 pm-11:07 am

1 stop17h 08m

Lambert-St Louis

Sat 12/6

7:43 pm-4:19 pm

1 stop19h 36m

$173

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 11/17

5:14 pm-9:07 am

1 stop16h 53m

Lambert-St Louis

Mon 11/24

7:43 pm-11:43 am

1 stop15h 00m

$176

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 11/17

5:14 pm-9:07 am

1 stop16h 53m

Lambert-St Louis

Fri 11/21

4:13 pm-10:31 am

1 stop17h 18m

$179

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 12/5

5:20 pm-10:14 am

1 stop17h 54m

Lambert-St Louis

Sat 12/6

7:43 pm-11:52 am

2 stops15h 09m

$182

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 12/3

11:05 am-3:40 pm

1 stop5h 35m

Lambert-St Louis

Tue 12/9

11:50 am-6:06 pm

1 stop5h 16m

$251

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Thu 12/4

6:00 am-3:40 pm

2 stops10h 40m

Lambert-St Louis

Sat 12/6

8:00 am-1:06 pm

1 stop4h 06m

$256

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Detroit to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Detroit to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $121. The month of July is another great option to travel to St. Louis, with average flight prices from Detroit averaging around $143.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $299. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $385. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Detroit at noon is the least expensive time of day to depart. momondo users have found prices as low as $279 when looking at flights departing at noon. In the morning is when there is more demand to fly to St. Louis, so prices are often more expensive at around $336 per ticket.

What is the cheapest Detroit to Lambert-St Louis flight route?

Fly from Detroit Metropolitan Wayne County to Lambert-St Louis for the best Detroit - Lambert-St Louis flight prices

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $271 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Detroit for as low as $69 on momondo.

What cabin class options are available on Detroit to Lambert-St Louis flights?

There are 4 cabin classes available to choose from on Detroit to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Detroit to St. Louis flights?

You could potentially save up to 41% on your flight if you consider stops on a Detroit to St. Louis flight.

How have Detroit to St. Louis flight prices changed over time?

As of November 2025, prices for Detroit to St. Louis flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Detroit to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to St. Louis (DTT to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to St. Louis

Best Price Found

$202

Fastest flight time

1h 40m

Direct flights

Every day

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Detroit in the past 72 hours is $202. The best round-trip flight deal from Detroit to St. Louis found on momondo in the last 72 hours is $291.
The fastest flight from Detroit to St. Louis takes 1h 40m
Direct flights go from Detroit to St. Louis every day.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
Search flight deals

  • How far is Detroit to Lambert-St Louis by plane?

    There are 454.1 mi between Detroit and Lambert-St Louis. A reasonable flight in good conditions will take 5h 32m.

  • When did momondo last update prices for flights from Detroit to Lambert-St Louis Airport?

    Prices for flights from Detroit to Lambert-St Louis Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Lambert-St Louis Airport?

  • How old do you have to be to fly from Detroit to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Detroit to St. Louis?

  • What is the most popular airline from Detroit to St. Louis?

Best airlines flying from Detroit to St. Louis

Compare and see reviews for airlines that fly from Detroit to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $36Free CancellationRating
6.3
8,113 reviews
Search Spirit Airlines flights
FrontierPriceFrom $111Free CancellationRating
5.8
3,115 reviews
Search Frontier flights
SouthwestPriceFrom $137Free CancellationRating
8.0
4,239 reviews
Search Southwest flights
DeltaPriceFrom $137Free CancellationRating
7.9
8,004 reviews
Search Delta flights

  • Southwest Flights From Detroit to St. Louis

    Southwest operates around 3 flights from Detroit to St. Louis every week. The average price of these flights found in the last 72 hours has been $297, but momondo users have found Southwest deals from Detroit to St. Louis from as low as $137 round-trip. Southwest has been scored 8.0/10 in 4,239 reviews.

  • Delta Flights From Detroit to St. Louis

    The best Delta deal for Detroit to St. Louis flight tickets found on momondo in the last 72 hours was $137, round-trip. It should be noted that an average Delta flight deal for this route in this time was higher, at $303 round-trip. Delta operates 16 flights out of Detroit into St. Louis in an average week, so prices vary by time and availability. 8,004 Delta reviews by users on momondo have scored the airline at 7.9/10.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Wentzville
Fenton
Collinsville
St. Peters
Alton
Farmington
Festus
Glencoe
Edwardsville
Clayton
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to St. Louis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to St. Louis from Detroit.

Can I find flights from Detroit to St. Louis with flexible booking policies on momondo?

All flight searches from Detroit to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to St. Louis?

Once you have performed a search for Detroit to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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