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Cheap flights from Detroit to St. Louis from $55

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to St. Louis departing on 1/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
12:38 pm - 10:33 pmDTW-STL
10h 55m1 stop
Frontier Logo
9:54 am - 5:17 pmSTL-DTW
6h 23m1 stop
$110Frontier
Find Deal
Sat, Dec 13 - Mon, Dec 15
Frontier Logo
12:38 pm - 10:33 pmDTW-STL
10h 55m1 stop
Frontier Logo
9:54 am - 5:17 pmSTL-DTW
6h 23m1 stop
$150Frontier
Find Deal
Sat, Dec 13 - Mon, Dec 15
Frontier Logo
10:29 pm - 9:09 pmDTW-STL
23h 40m1 stop
Frontier Logo
7:57 pm - 6:07 pmSTL-DTW
21h 10m1 stop
$156Frontier
Find Deal
Mon, Nov 24 - Thu, Nov 27
Frontier Logo
12:20 pm - 10:04 amDTW-STL
22h 44m1 stop
Frontier Logo
10:42 am - 5:49 pmSTL-DTW
6h 07m1 stop
$158Frontier
Find Deal
Fri, Jan 16 - Sun, Jan 18
Frontier Logo
7:40 pm - 9:29 amDTW-STL
14h 49m1 stop
Frontier Logo
7:57 pm - 11:43 amSTL-DTW
14h 46m1 stop
$168Frontier
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Sat, Nov 22 - Sun, Nov 23
Multiple Airlines Logo
12:20 pm - 6:32 pmDTW-STL
7h 12m1 stop
Multiple Airlines Logo
8:32 pm - 1:30 pmSTL-DTW
15h 58m1 stop
$171Multiple Airlines
Find Deal
Fri, Jan 16 - Mon, Jan 19
Multiple Airlines Logo
11:13 am - 10:33 pmDTW-STL
12h 20m1 stop
Multiple Airlines Logo
12:04 pm - 7:52 pmSTL-DTW
6h 48m1 stop
$177Multiple Airlines
Find Deal
Mon, Dec 8 - Thu, Dec 11
Multiple Airlines Logo
6:59 pm - 11:07 amDTW-STL
17h 08m1 stop
Multiple Airlines Logo
10:42 am - 8:07 amSTL-DTW
20h 25m1 stop
$181Multiple Airlines
Find Deal
Wed, Dec 3 - Sun, Dec 7
Multiple Airlines Logo
2:50 pm - 9:47 amDTW-STL
19h 57m1 stop
Multiple Airlines Logo
10:47 am - 7:52 pmSTL-DTW
8h 05m1 stop
$183Multiple Airlines
Find Deal
Sat, Dec 13 - Mon, Dec 15
Multiple Airlines Logo
10:36 am - 10:33 pmDTW-STL
12h 57m2 stops
Multiple Airlines Logo
12:04 pm - 7:52 pmSTL-DTW
6h 48m1 stop
$184Multiple Airlines
Find Deal
Mon, Dec 8 - Thu, Dec 11

Frontier flights from Detroit to St. Louis

Our best Frontier deals on Detroit to St. Louis flight tickets
Frontier
Dec 13
DTW12:38 pmDetroit Metropolitan Wayne County
10h 55m
1 stop
STL10:33 pmLambert-St Louis
Dec 15
STL9:54 amLambert-St Louis
6h 23m
1 stop
DTW5:17 pmDetroit Metropolitan Wayne County
$110
Find similar
Frontier
Dec 13
DTW12:38 pmDetroit Metropolitan Wayne County
10h 55m
1 stop
STL10:33 pmLambert-St Louis
Dec 15
STL9:54 amLambert-St Louis
6h 23m
1 stop
DTW5:17 pmDetroit Metropolitan Wayne County
$150
Find similar
Frontier
Nov 24
DTW10:29 pmDetroit Metropolitan Wayne County
23h 40m
1 stop
STL9:09 pmLambert-St Louis
Nov 27
STL7:57 pmLambert-St Louis
21h 10m
1 stop
DTW6:07 pmDetroit Metropolitan Wayne County
$156
Find similar

United Airlines flights from Detroit to St. Louis

Our best United Airlines deals on Detroit to St. Louis flight tickets
United Airlines
Jan 15
DTW11:05 amDetroit Metropolitan Wayne County
4h 25m
1 stop
STL2:30 pmLambert-St Louis
Jan 19
STL3:11 pmLambert-St Louis
4h 15m
1 stop
DTW8:26 pmDetroit Metropolitan Wayne County
$191
Find similar
United Airlines
Dec 9
DTW11:05 amDetroit Metropolitan Wayne County
5h 35m
1 stop
STL3:40 pmLambert-St Louis
Dec 16
STL5:27 pmLambert-St Louis
5h 04m
1 stop
DTW11:31 pmDetroit Metropolitan Wayne County
$211
Find similar
United Airlines
Dec 3
DTW6:00 amDetroit Metropolitan Wayne County
5h 50m
1 stop
STL10:50 amLambert-St Louis
Dec 6
STL6:42 pmLambert-St Louis
3h 49m
1 stop
DTW11:31 pmDetroit Metropolitan Wayne County
$214
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 12, 2025.
Use the filters below to find and compare flights from Detroit to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sat 12/13

12:38 pm-10:33 pm

1 stop10h 55m

Lambert-St Louis

Mon 12/15

9:54 am-5:17 pm

1 stop6h 23m

$110

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sat 12/13

12:38 pm-10:33 pm

1 stop10h 55m

Lambert-St Louis

Mon 12/15

9:54 am-5:17 pm

1 stop6h 23m

$150

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 11/24

10:29 pm-9:09 pm

1 stop23h 40m

Lambert-St Louis

Thu 11/27

7:57 pm-6:07 pm

1 stop21h 10m

$156

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 1/16

12:20 pm-10:04 am

1 stop22h 44m

Lambert-St Louis

Sun 1/18

10:42 am-5:49 pm

1 stop6h 07m

$158

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sat 11/22

7:40 pm-9:29 am

1 stop14h 49m

Lambert-St Louis

Sun 11/23

7:57 pm-11:43 am

1 stop14h 46m

$168

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 1/16

12:20 pm-6:32 pm

1 stop7h 12m

Lambert-St Louis

Mon 1/19

8:32 pm-1:30 pm

1 stop15h 58m

$171

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 12/8

11:13 am-10:33 pm

1 stop12h 20m

Lambert-St Louis

Thu 12/11

12:04 pm-7:52 pm

1 stop6h 48m

$177

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 12/3

6:59 pm-11:07 am

1 stop17h 08m

Lambert-St Louis

Sun 12/7

10:42 am-8:07 am

1 stop20h 25m

$181

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sat 12/13

2:50 pm-9:47 am

1 stop19h 57m

Lambert-St Louis

Mon 12/15

10:47 am-7:52 pm

1 stop8h 05m

$183

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 12/8

10:36 am-10:33 pm

2 stops12h 57m

Lambert-St Louis

Thu 12/11

12:04 pm-7:52 pm

1 stop6h 48m

$184

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Detroit to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Detroit to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $121. The month of July is another great option to travel to St. Louis, with average flight prices from Detroit averaging around $143.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $299. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $385. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Detroit at noon is the least expensive time of day to depart. momondo users have found prices as low as $279 when looking at flights departing at noon. In the morning is when there is more demand to fly to St. Louis, so prices are often more expensive at around $336 per ticket.

What is the cheapest Detroit to Lambert-St Louis flight route?

Fly from Detroit Metropolitan Wayne County to Lambert-St Louis for the best Detroit - Lambert-St Louis flight prices

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $268 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Detroit for as low as $69 on momondo.

What cabin class options are available on Detroit to Lambert-St Louis flights?

There are 4 cabin classes available to choose from on Detroit to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Detroit to St. Louis flights?

You could potentially save up to 41% on your flight if you consider stops on a Detroit to St. Louis flight.

How have Detroit to St. Louis flight prices changed over time?

As of November 2025, prices for Detroit to St. Louis flights are approximately 32% cheaper when compared to flights at the same time last year.

When to book flights from Detroit to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to St. Louis (DTT to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to St. Louis

Best Price Found

$202

Fastest flight time

1h 40m

Direct flights

Every day

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Detroit in the past 72 hours is $202. The best round-trip flight deal from Detroit to St. Louis found on momondo in the last 72 hours is $291.
The fastest flight from Detroit to St. Louis takes 1h 40m
Direct flights go from Detroit to St. Louis every day.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
Search flight deals

  • How far is Detroit to Lambert-St Louis by plane?

    There are 454.1 mi between Detroit and Lambert-St Louis. A reasonable flight in good conditions will take 1h 40m.

  • When did momondo last update prices for flights from Detroit to Lambert-St Louis Airport?

    Prices for flights from Detroit to Lambert-St Louis Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Lambert-St Louis Airport?

  • How old do you have to be to fly from Detroit to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Detroit to St. Louis?

  • What is the most popular airline from Detroit to St. Louis?

Best airlines flying from Detroit to St. Louis

Compare and see reviews for airlines that fly from Detroit to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $36Free CancellationRating
6.3
8,137 reviews
Search Spirit Airlines flights
FrontierPriceFrom $111Free CancellationRating
5.8
3,113 reviews
Search Frontier flights
SouthwestPriceFrom $137Free CancellationRating
8.0
4,235 reviews
Search Southwest flights
DeltaPriceFrom $137Free CancellationRating
7.9
8,008 reviews
Search Delta flights

  • Southwest Flights From Detroit to St. Louis

    Southwest operates around 11 flights from Detroit to St. Louis every week. The average price of these flights found in the last 72 hours has been $297, but momondo users have found Southwest deals from Detroit to St. Louis from as low as $137 round-trip. Southwest has been scored 8.0/10 in 4,235 reviews.

  • Delta Flights From Detroit to St. Louis

    The best Delta deal for Detroit to St. Louis flight tickets found on momondo in the last 72 hours was $137, round-trip. It should be noted that an average Delta flight deal for this route in this time was higher, at $303 round-trip. Delta operates 24 flights out of Detroit into St. Louis in an average week, so prices vary by time and availability. 8,008 Delta reviews by users on momondo have scored the airline at 7.9/10.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Wentzville
Fenton
Collinsville
St. Peters
Alton
Farmington
Festus
Glencoe
Edwardsville
Clayton
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to St. Louis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to St. Louis from Detroit.

Can I find flights from Detroit to St. Louis with flexible booking policies on momondo?

All flight searches from Detroit to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to St. Louis?

Once you have performed a search for Detroit to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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