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Cheap flights from Detroit to St. Louis from $63

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to St. Louis departing on 11/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:00 am - 9:07 amDTW-STL
28h 07m1 stop
Frontier Logo
11:07 am - 5:12 pmSTL-DTW
5h 05m1 stop
$212Frontier
Find Deal
lun., oct. 27 - jue., oct. 30
Multiple Airlines Logo
6:55 pm - 4:01 pmDTW-STL
22h 06m1 stop
Multiple Airlines Logo
3:14 pm - 12:44 pmSTL-DTW
20h 30m1 stop
$217Multiple Airlines
Find Deal
jue., nov. 13 - jue., nov. 20
American Airlines Logo
5:33 am - 8:09 amDTW-STL
3h 36m1 stop
American Airlines Logo
4:42 pm - 11:52 pmSTL-DTW
6h 10m1 stop
$223American Airlines
Find Deal
vie., nov. 14 - dom., nov. 16
American Airlines Logo
6:45 am - 3:02 pmDTW-STL
9h 17m1 stop
American Airlines Logo
9:12 am - 2:52 pmSTL-DTW
4h 40m1 stop
$229American Airlines
Find Deal
mar., nov. 18 - jue., nov. 20
Southwest Logo
8:00 am - 8:55 amDTW-STL
1h 55mnonstop
Southwest Logo
8:10 pm - 10:40 pmSTL-DTW
1h 30mnonstop
$255Southwest
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jue., nov. 6 - lun., nov. 10
Southwest Logo
8:00 am - 8:55 amDTW-STL
1h 55mnonstop
Southwest Logo
5:45 pm - 11:40 pmSTL-DTW
4h 55m1 stop
$265Southwest
Find Deal
jue., nov. 6 - lun., nov. 10
Spirit Airlines Logo
9:39 pm - 5:57 pmDTW-STL
21h 18m2 stops
Spirit Airlines Logo
6:21 pm - 12:03 pmSTL-DTW
16h 42m2 stops
$275Spirit Airlines
Find Deal
mié., nov. 12 - dom., nov. 16
Delta Logo
6:10 pm - 11:07 pmDTW-STL
5h 57m1 stop
Delta Logo
6:40 am - 9:13 amSTL-DTW
1h 33mnonstop
$278Delta
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sáb., nov. 8 - lun., nov. 10
Delta Logo
8:55 am - 9:46 amDTW-STL
1h 51mnonstop
Delta Logo
5:00 pm - 7:33 pmSTL-DTW
1h 33mnonstop
$281Delta
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sáb., nov. 15 - sáb., nov. 15
Spirit Airlines Logo
10:30 am - 10:02 amDTW-STL
24h 32m2 stops
Spirit Airlines Logo
7:15 pm - 12:59 pmSTL-DTW
16h 44m1 stop
$294Spirit Airlines
Find Deal
mié., oct. 29 - sáb., nov. 1

Southwest flights from Detroit to St. Louis

Our best Southwest deals on Detroit to St. Louis flight tickets
Southwest
Nov 6
DTW8:00 amDetroit Metropolitan Wayne County
1h 55m
STL8:55 amLambert-St Louis
Nov 10
STL8:10 pmLambert-St Louis
1h 30m
DTW10:40 pmDetroit Metropolitan Wayne County
$255
Find similar
Southwest
Nov 6
DTW8:00 amDetroit Metropolitan Wayne County
1h 55m
STL8:55 amLambert-St Louis
Nov 10
STL5:45 pmLambert-St Louis
4h 55m
1 stop
DTW11:40 pmDetroit Metropolitan Wayne County
$265
Find similar
Southwest
Nov 6
DTW8:00 amDetroit Metropolitan Wayne County
1h 55m
STL8:55 amLambert-St Louis
Nov 10
STL3:15 pmLambert-St Louis
7h 25m
2 stops
DTW11:40 pmDetroit Metropolitan Wayne County
$270
Find similar

Spirit Airlines flights from Detroit to St. Louis

Our best Spirit Airlines deals on Detroit to St. Louis flight tickets
Spirit Airlines
Nov 12
DTW9:39 pmDetroit Metropolitan Wayne County
21h 18m
2 stops
STL5:57 pmLambert-St Louis
Nov 16
STL6:21 pmLambert-St Louis
16h 42m
2 stops
DTW12:03 pmDetroit Metropolitan Wayne County
$275
Find similar
Spirit Airlines
Oct 29
DTW10:30 amDetroit Metropolitan Wayne County
24h 32m
2 stops
STL10:02 amLambert-St Louis
Nov 1
STL7:15 pmLambert-St Louis
16h 44m
1 stop
DTW12:59 pmDetroit Metropolitan Wayne County
$294
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 16, 2025.
Use the filters below to find and compare flights from Detroit to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

lun. 10/27

6:00 am-9:07 am

1 stop28h 07m

Lambert-St Louis

jue. 10/30

11:07 am-5:12 pm

1 stop5h 05m

$212

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

jue. 11/13

6:55 pm-4:01 pm

1 stop22h 06m

Lambert-St Louis

jue. 11/20

3:14 pm-12:44 pm

1 stop20h 30m

$217

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

vie. 11/14

5:33 am-8:09 am

1 stop3h 36m

Lambert-St Louis

dom. 11/16

4:42 pm-11:52 pm

1 stop6h 10m

$223

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

mar. 11/18

6:45 am-3:02 pm

1 stop9h 17m

Lambert-St Louis

jue. 11/20

9:12 am-2:52 pm

1 stop4h 40m

$229

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

jue. 11/6

8:00 am-8:55 am

Nonstop1h 55m

Lambert-St Louis

lun. 11/10

8:10 pm-10:40 pm

Nonstop1h 30m

$255

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

jue. 11/6

8:00 am-8:55 am

Nonstop1h 55m

Lambert-St Louis

lun. 11/10

5:45 pm-11:40 pm

1 stop4h 55m

$265

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

mié. 11/12

9:39 pm-5:57 pm

2 stops21h 18m

Lambert-St Louis

dom. 11/16

6:21 pm-12:03 pm

2 stops16h 42m

$275

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

sáb. 11/8

6:10 pm-11:07 pm

1 stop5h 57m

Lambert-St Louis

lun. 11/10

6:40 am-9:13 am

Nonstop1h 33m

$278

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

sáb. 11/15

8:55 am-9:46 am

Nonstop1h 51m

Lambert-St Louis

sáb. 11/15

5:00 pm-7:33 pm

Nonstop1h 33m

$281

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

mié. 10/29

10:30 am-10:02 am

2 stops24h 32m

Lambert-St Louis

sáb. 11/1

7:15 pm-12:59 pm

1 stop16h 44m

$294

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Detroit to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Detroit to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $121. The month of July is another great option to travel to St. Louis, with average flight prices from Detroit averaging around $143.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $300. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $376. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Detroit at noon is the least expensive time of day to depart. momondo users have found prices as low as $279 when looking at flights departing at noon. In the morning is when there is more demand to fly to St. Louis, so prices are often more expensive at around $339 per ticket.

What is the cheapest Detroit to Lambert-St Louis flight route?

Fly from Detroit Metropolitan Wayne County to Lambert-St Louis for the best Detroit - Lambert-St Louis flight prices

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $271 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Detroit for as low as $69 on momondo.

What cabin class options are available on Detroit to Lambert-St Louis flights?

There are 4 cabin classes available to choose from on Detroit to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Detroit to St. Louis flights?

No. A direct flight is the cheapest option for a flight between Detroit to St. Louis.

How have Detroit to St. Louis flight prices changed over time?

As of October 2025, prices for Detroit to St. Louis flights are approximately 60% cheaper when compared to flights at the same time last year.

When to book flights from Detroit to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to St. Louis (DTT to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to St. Louis

Best Price Found

$170

Fastest flight time

1h 37m

Direct flights

Every day

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Detroit in the past 72 hours is $170. The best round-trip flight deal from Detroit to St. Louis found on momondo in the last 72 hours is $293.
The fastest flight from Detroit to St. Louis takes 1h 37m
Direct flights go from Detroit to St. Louis every day.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
Search flight deals

  • How far is Detroit to Lambert-St Louis by plane?

    There are 454.1 mi between Detroit and Lambert-St Louis. A reasonable flight in good conditions will take 1h 45m.

  • When did momondo last update prices for flights from Detroit to Lambert-St Louis Airport?

    Prices for flights from Detroit to Lambert-St Louis Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Lambert-St Louis Airport?

  • How old do you have to be to fly from Detroit to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Detroit to St. Louis?

  • What is the most popular airline from Detroit to St. Louis?

Best airlines flying from Detroit to St. Louis

Compare and see reviews for airlines that fly from Detroit to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $36Free CancellationRating
6.3
8,099 reviews
Search Spirit Airlines flights
FrontierPriceFrom $111Free CancellationRating
5.8
3,137 reviews
Search Frontier flights
DeltaPriceFrom $139Free CancellationRating
7.9
7,982 reviews
Search Delta flights
SouthwestPriceFrom $148Free CancellationRating
8.0
4,241 reviews
Search Southwest flights
United AirlinesPriceFrom $232Free CancellationRating
7.4
8,982 reviews
Search United Airlines flights

  • Southwest Flights From Detroit to St. Louis

    Southwest operates around 10 flights from Detroit to St. Louis every week. The average price of these flights found in the last 72 hours has been $299, but momondo users have found Southwest deals from Detroit to St. Louis from as low as $148 round-trip. Southwest has been scored 8.0/10 in 4,241 reviews.

  • Delta Flights From Detroit to St. Louis

    The best Delta deal for Detroit to St. Louis flight tickets found on momondo in the last 72 hours was $139, round-trip. It should be noted that an average Delta flight deal for this route in this time was higher, at $303 round-trip. Delta operates 23 flights out of Detroit into St. Louis in an average week, so prices vary by time and availability. 7,982 Delta reviews by users on momondo have scored the airline at 7.9/10.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Wentzville
Collinsville
Fenton
St. Peters
Alton
Farmington
Festus
Glencoe
Clayton
Edwardsville
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to St. Louis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to St. Louis from Detroit.

Can I find flights from Detroit to St. Louis with flexible booking policies on momondo?

All flight searches from Detroit to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to St. Louis?

Once you have performed a search for Detroit to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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