Cheap flights from Detroit Metropolitan Wayne County Airport to Missouri from $98

In general, July is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $400. If you aren’t able to travel to Missouri during the month of July, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $404.

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to Missouri is on a Saturday when prices can be found for as low as $374. Flights from Detroit Metropolitan Wayne County Airport to Missouri on a Sunday will generally be more expensive and average around $497. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Detroit Metropolitan Wayne County Airport to Missouri at noon for as low as $358. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the morning, with an average ticket price of $455. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Detroit Metropolitan Wayne County to Lambert-St Louis for the best Detroit Metropolitan Wayne County - Missouri flight prices

You are more likely to see cheaper flights to Missouri from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $385 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Detroit Metropolitan Wayne County Airport for as low as $279 on momondo.

There are 4 cabin classes available to choose from on Detroit Metropolitan Wayne County Airport to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier and United Airlines are the most popular carriers operating from Detroit Metropolitan Wayne County to Missouri

Delta, Southwest and Frontier are the top three most popular airlines that fly to Missouri from Detroit Metropolitan Wayne County Airport according to our data. Delta is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 5 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

As of November 2026, there are 8 flights per day flying from Detroit Metropolitan Wayne County Airport to Missouri. The most common time of day flights depart is 8:00PM, with 41% of flights taking off in the afternoon.

As of November 2026, there are 59 flights per week flying from Detroit Metropolitan Wayne County Airport to Missouri. The most common day of the week flights depart is Fri, with 42% of flights taking off on this day.