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Cheap flights from Detroit Metropolitan Wayne County Airport to Greenville from $92

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Greenville departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:08 am - 7:57 am
DTW
-
GSP
21h 49m
1 stop
Multiple Airlines Logo
4:57 pm - 5:22 pm
GSP
-
DTW
24h 25m
1 stop
$198Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
5:13 pm - 3:03 pm
DTW
-
GSP
21h 50m
2 stops
Multiple Airlines Logo
4:57 pm - 5:22 pm
GSP
-
DTW
24h 25m
1 stop
$207Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
10:14 am - 7:57 am
DTW
-
GSP
21h 43m
1 stop
Multiple Airlines Logo
3:13 pm - 12:44 pm
GSP
-
DTW
21h 31m
1 stop
$209Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
10:14 am - 4:07 pm
DTW
-
GSP
29h 53m
1 stop
Multiple Airlines Logo
8:13 pm - 12:44 pm
GSP
-
DTW
16h 31m
1 stop
$211Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
Multiple Airlines Logo
2:56 pm - 4:07 pm
DTW
-
GSP
25h 11m
2 stops
Multiple Airlines Logo
3:13 pm - 12:44 pm
GSP
-
DTW
21h 31m
1 stop
$216Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
Multiple Airlines Logo
10:18 am - 7:57 am
DTW
-
GSP
21h 39m
1 stop
Multiple Airlines Logo
8:37 am - 12:55 pm
GSP
-
DTW
28h 18m
1 stop
$219Multiple Airlines
Wed, Sep 2 - Sun, Sep 6
Multiple Airlines Logo
5:13 pm - 7:57 am
DTW
-
GSP
14h 44m
2 stops
Multiple Airlines Logo
3:13 pm - 12:44 pm
GSP
-
DTW
21h 31m
1 stop
$232Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
10:14 am - 7:57 am
DTW
-
GSP
21h 43m
1 stop
Multiple Airlines Logo
8:45 pm - 8:54 am
GSP
-
DTW
12h 09m
1 stop
$238Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
11:00 am - 6:30 pm
DTW
-
GSP
7h 30m
1 stop
Multiple Airlines Logo
8:15 pm - 11:54 am
GSP
-
DTW
15h 39m
1 stop
$242Multiple Airlines
Fri, Sep 18 - Mon, Sep 21
Multiple Airlines Logo
10:14 am - 7:57 am
DTW
-
GSP
21h 43m
1 stop
Multiple Airlines Logo
8:37 am - 12:55 pm
GSP
-
DTW
28h 18m
1 stop
$244Multiple Airlines
Sat, Aug 15 - Sun, Aug 23

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Southwest flights from Detroit Metropolitan Wayne County Airport to Greenville

Our best Southwest deals on Detroit Metropolitan Wayne County Airport to Greenville flight tickets
Southwest
Aug 5
DTW6:25 amDetroit Metropolitan Wayne County
10h 20m
2 stops
GSP4:45 pmGreenville
Aug 11
GSP1:20 pmGreenville
8h 10m
2 stops
DTW9:30 pmDetroit Metropolitan Wayne County
$331
Southwest
Jul 9
DTW10:45 amDetroit Metropolitan Wayne County
10h 55m
2 stops
GSP9:40 pmGreenville
Jul 16
GSP6:50 pmGreenville
5h 20m
1 stop
DTW12:10 amDetroit Metropolitan Wayne County
$494
Southwest
Jul 9
DTW1:25 pmDetroit Metropolitan Wayne County
9h 30m
2 stops
GSP10:55 pmGreenville
Jul 16
GSP1:55 pmGreenville
7h 10m
2 stops
DTW9:05 pmDetroit Metropolitan Wayne County
$499

Delta flights from Detroit Metropolitan Wayne County Airport to Greenville

Our best Delta deals on Detroit Metropolitan Wayne County Airport to Greenville flight tickets
Delta
Jul 11
DTW8:05 pmDetroit Metropolitan Wayne County
1h 42m
GSP9:47 pmGreenville
Jul 19
GSP7:10 amGreenville
1h 47m
DTW8:57 amDetroit Metropolitan Wayne County
$469
Delta
Jul 11
DTW5:17 amDetroit Metropolitan Wayne County
4h 01m
1 stop
GSP9:18 amGreenville
Jul 18
GSP7:10 amGreenville
1h 47m
DTW8:57 amDetroit Metropolitan Wayne County
$479
Delta
Jul 11
DTW6:17 amDetroit Metropolitan Wayne County
6h 01m
1 stop
GSP12:18 pmGreenville
Jul 18
GSP6:00 amGreenville
4h 10m
1 stop
DTW10:10 amDetroit Metropolitan Wayne County
$489

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/12

10:08 am-7:57 am

1 stop21h 49m

Greenville

Mon 8/17

4:57 pm-5:22 pm

1 stop24h 25m

$198

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/12

5:13 pm-3:03 pm

2 stops21h 50m

Greenville

Mon 8/17

4:57 pm-5:22 pm

1 stop24h 25m

$207

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/12

10:14 am-7:57 am

1 stop21h 43m

Greenville

Mon 8/17

3:13 pm-12:44 pm

1 stop21h 31m

$209

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 8/13

10:14 am-4:07 pm

1 stop29h 53m

Greenville

Mon 8/17

8:13 pm-12:44 pm

1 stop16h 31m

$211

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 8/13

2:56 pm-4:07 pm

2 stops25h 11m

Greenville

Mon 8/17

3:13 pm-12:44 pm

1 stop21h 31m

$216

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 9/2

10:18 am-7:57 am

1 stop21h 39m

Greenville

Sun 9/6

8:37 am-12:55 pm

1 stop28h 18m

$219

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/12

5:13 pm-7:57 am

2 stops14h 44m

Greenville

Mon 8/17

3:13 pm-12:44 pm

1 stop21h 31m

$232

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/12

10:14 am-7:57 am

1 stop21h 43m

Greenville

Mon 8/17

8:45 pm-8:54 am

1 stop12h 09m

$238
Quickest round-trip

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 9/18

11:00 am-6:30 pm

1 stop7h 30m

Greenville

Mon 9/21

8:15 pm-11:54 am

1 stop15h 39m

$242

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sat 8/15

10:14 am-7:57 am

1 stop21h 43m

Greenville

Sun 8/23

8:37 am-12:55 pm

1 stop28h 18m

$244

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of July is another great option to travel to Greenville, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $399.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Thursday is the cheapest day to fly to Greenville from Detroit Metropolitan Wayne County Airport. The lowest ticket price found for a Thursday departure recently was $469. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $693. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Detroit Metropolitan Wayne County Airport to Greenville during this time can be as low as $469. Flights to Greenville are more costly in the evening, with an average ticket price of $549. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Detroit Metropolitan Wayne County to Greenville flight route?

Fly from Detroit Metropolitan Wayne County to Greenville for the best Detroit Metropolitan Wayne County - Greenville flight prices

What cabin class options are available on Detroit Metropolitan Wayne County Airport to Greenville flights?

There are 4 cabin classes available to choose from on Detroit Metropolitan Wayne County Airport to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Greenville flights?

You could potentially save up to 31% on your flight if you consider stops on a Detroit Metropolitan Wayne County Airport to Greenville flight.

How have Detroit Metropolitan Wayne County Airport to Greenville flight prices changed over time?

As of June 2026, prices for Detroit Metropolitan Wayne County Airport to Greenville flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Greenville (DTW to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Greenville

Best Price Found

$333

Fastest flight time

1h 41m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in Greenville

1 airport
The best one-way flight to Greenville from Detroit Metropolitan Wayne County Airport in the past 72 hours is $333. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to Greenville found on momondo in the last 72 hours is $399.
The fastest flight from Detroit Metropolitan Wayne County Airport to Greenville takes 1h 41m
Direct flights go from Detroit Metropolitan Wayne County Airport to Greenville on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Delta.
There is 1 airport in Greenville. From Detroit Metropolitan Wayne County Airport there are direct flights to Greenville (GSP).
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Greenville

  • How far is Detroit Metropolitan Wayne County to Greenville by plane?

    The distance between Detroit Metropolitan Wayne County and Greenville is about 511.4 mi. By plane, this route typically takes 1h 41m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Greenville Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Greenville Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit Metropolitan Wayne County Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to Greenville?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Greenville?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Greenville

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $399Free CancellationRating
7.8
8,451 reviews
Search Delta flights

  • Delta Flights From Detroit Metropolitan Wayne County Airport to Greenville

    Delta flies from Detroit Metropolitan Wayne County Airport to Greenville around 12 times per week, with 8,455 momondo users rating the airline 7.8/10. The cheapest Delta deal from Detroit Metropolitan Wayne County Airport to Greenville in the last 72 hours was $399 (round-trip), much lower than the average airfare cost of $553 for Delta flights on this route.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Greenville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Detroit to Greenville. momondo saves you time and could save you money on your trip.

Can I find flights from Detroit to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Greenville?

Once all potential Detroit to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Greenville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to Greenville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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