What airlines fly to Syracuse?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Syracuse from Des Moines according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Syracuse. Keep in mind that there are 3 different airlines that fly to Syracuse on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Syracuse Hancock Intl?

Allegiant Air and American Airlines are the most popular carriers operating from Des Moines to Syracuse Hancock Intl

When did momondo last update prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport?

Prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Syracuse Hancock Intl Airport?

The number of operators available for flights from Des Moines Airport to Syracuse Hancock Intl Airport is 3 as of August 2026.

How old do you have to be to fly from Des Moines Airport to Syracuse Hancock Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Syracuse Hancock Intl Airport.

What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?

The travel and health documents you'll need for your trip to Syracuse Hancock Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Syracuse Hancock Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$160 Cheap Flights from Des Moines to Syracuse in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Syracuse

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One-way

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6:00 am - 12:12 pmDSM Des Moines-SYR Syracuse Hancock Intl

5h 12m1 stop Detroit Metropolitan Wayne County

6:08 am - 11:40 amSYR Syracuse Hancock Intl-DSM Des Moines

6h 32m1 stop New York LaGuardia

$329Delta

Sat, Oct 17 - Sat, Oct 24

3:46 pm - 11:29 pmDSM Des Moines-SYR Syracuse Hancock Intl

6h 43m1 stop Minneapolis St Paul

6:22 am - 9:42 amSYR Syracuse Hancock Intl-DSM Des Moines

4h 20m1 stop Detroit Metropolitan Wayne County

$329Delta

Wed, Oct 21 - Sat, Oct 24

10:59 am - 6:48 pmDSM Des Moines-SYR Syracuse Hancock Intl

6h 49m1 stop Minneapolis St Paul

7:20 am - 2:06 pmSYR Syracuse Hancock Intl-DSM Des Moines

7h 46m1 stop Minneapolis St Paul

$329Delta

Sat, Sep 19 - Tue, Sep 22

2:01 pm - 11:59 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 58m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

6:12 am - 12:45 pmSYR Syracuse Hancock Intl-DSM Des Moines

7h 33m1 stop Philadelphia

$334American Airlines

Wed, Oct 21 - Sat, Oct 24

3:01 pm - 9:28 pmDSM Des Moines-SYR Syracuse Hancock Intl

5h 27m1 stop Washington, D.C. Reagan-National

5:27 pm - 12:14 amSYR Syracuse Hancock Intl-DSM Des Moines

7h 47m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$334American Airlines

Sat, Oct 17 - Sat, Oct 24

1:35 pm - 11:21 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 46m1 stop Denver Intl

2:55 pm - 9:28 pmSYR Syracuse Hancock Intl-DSM Des Moines

7h 33m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$334United Airlines

Sat, Sep 19 - Tue, Sep 22

2:01 pm - 11:29 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 28m2 stops Chicago O'Hare Intl Philadelphia

6:59 pm - 12:14 amSYR Syracuse Hancock Intl-DSM Des Moines

6h 15m1 stop Chicago O'Hare Intl

$334American Airlines

Wed, Oct 21 - Sat, Oct 24

6:24 am - 2:14 pmDSM Des Moines-SYR Syracuse Hancock Intl

6h 50m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

10:25 am - 5:28 pmSYR Syracuse Hancock Intl-DSM Des Moines

8h 03m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$339United Airlines

Sat, Sep 19 - Tue, Sep 22

3:04 pm - 10:37 amDSM Des Moines-SYR Syracuse Hancock Intl

18h 33m1 stop Fort Myers SW Florida Intl

8:55 pm - 11:55 amSYR Syracuse Hancock Intl-DSM Des Moines

40h 00m2 stops Nashville Intl Orlando

$452Multiple Airlines

Fri, Oct 9 - Mon, Oct 12

9:39 am - 5:18 pmDSM Des Moines-SYR Syracuse Hancock Intl

30h 39m2 stops Nashville Intl Orlando

7:29 pm - 4:09 pmSYR Syracuse Hancock Intl-DSM Des Moines

21h 40m1 stop Tampa

$508Multiple Airlines

Thu, Sep 17 - Sun, Sep 20

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American Airlines flights from Des Moines to Syracuse

Our best American Airlines deals on Des Moines to Syracuse flight tickets

American Airlines

Oct 21

DSM2:01 pmDes Moines

8h 58m

2 stops

SYR11:59 pmSyracuse Hancock Intl

Oct 24

SYR6:12 amSyracuse Hancock Intl

7h 33m

1 stop

DSM12:45 pmDes Moines

$334

American Airlines

Oct 21

DSM2:01 pmDes Moines

8h 58m

2 stops

SYR11:59 pmSyracuse Hancock Intl

Oct 24

SYR5:27 pmSyracuse Hancock Intl

7h 47m

2 stops

DSM12:14 amDes Moines

$339

American Airlines

Sep 30

DSM5:56 pmDes Moines

5h 11m

1 stop

SYR12:07 amSyracuse Hancock Intl

Oct 5

SYR5:36 pmSyracuse Hancock Intl

6h 09m

1 stop

DSM10:45 pmDes Moines

$354

Delta flights from Des Moines to Syracuse

Our best Delta deals on Des Moines to Syracuse flight tickets

Delta

Oct 21

DSM3:46 pmDes Moines

6h 43m

1 stop

SYR11:29 pmSyracuse Hancock Intl

Oct 24

SYR6:22 amSyracuse Hancock Intl

4h 20m

1 stop

DSM9:42 amDes Moines

$329

Delta

Sep 9

DSM5:35 pmDes Moines

4h 23m

1 stop

SYR10:58 pmSyracuse Hancock Intl

Sep 13

SYR6:20 amSyracuse Hancock Intl

4h 18m

1 stop

DSM9:38 amDes Moines

$377

Delta

Sep 17

DSM6:00 amDes Moines

5h 55m

1 stop

SYR12:55 pmSyracuse Hancock Intl

Sep 20

SYR7:20 amSyracuse Hancock Intl

7h 46m

1 stop

DSM2:06 pmDes Moines

$433

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Sat 10/17

6:00 am-12:12 pm

1 stop5h 12m

Syracuse Hancock Intl

Sat 10/24

6:08 am-11:40 am

1 stop6h 32m

$329

Quickest round-trip

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Wed 10/21

3:46 pm-11:29 pm

1 stop6h 43m

Syracuse Hancock Intl

Sat 10/24

6:22 am-9:42 am

1 stop4h 20m

$329

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Sat 9/19

10:59 am-6:48 pm

1 stop6h 49m

Syracuse Hancock Intl

Tue 9/22

7:20 am-2:06 pm

1 stop7h 46m

$329

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Wed 10/21

2:01 pm-11:59 pm

2 stops8h 58m

Syracuse Hancock Intl

Sat 10/24

6:12 am-12:45 pm

1 stop7h 33m

$334

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Sat 10/17

3:01 pm-9:28 pm

1 stop5h 27m

Syracuse Hancock Intl

Sat 10/24

5:27 pm-12:14 am

2 stops7h 47m

$334

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Sat 9/19

1:35 pm-11:21 pm

1 stop8h 46m

Syracuse Hancock Intl

Tue 9/22

2:55 pm-9:28 pm

2 stops7h 33m

$334

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Wed 10/21

2:01 pm-11:29 pm

2 stops8h 28m

Syracuse Hancock Intl

Sat 10/24

6:59 pm-12:14 am

1 stop6h 15m

$334

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Sat 9/19

6:24 am-2:14 pm

2 stops6h 50m

Syracuse Hancock Intl

Tue 9/22

10:25 am-5:28 pm

2 stops8h 03m

$339

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Fri 10/9

3:04 pm-10:37 am

1 stop18h 33m

Syracuse Hancock Intl

Mon 10/12

8:55 pm-11:55 am

2 stops40h 00m

$452

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Thu 9/17

9:39 am-5:18 pm

2 stops30h 39m

Syracuse Hancock Intl

Sun 9/20

7:29 pm-4:09 pm

1 stop21h 40m

$508

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Syracuse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Syracuse?

The month of September is, on average, the cheapest month to fly to Syracuse from Des Moines, with most prices found around $0. If you aren’t able to travel to Syracuse during the month of September, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $273.

Can stopping save me money on Des Moines to Syracuse flights?

You could potentially save up to 38% on your flight if you consider stops on a Des Moines to Syracuse flight.

When to book flights from Des Moines to Syracuse

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Syracuse according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Syracuse (DSM to SYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Syracuse

Best Price Found	$160
Fastest flight time	4h 38m
Direct flights	None

The best one-way flight to Syracuse from Des Moines in the past 72 hours is $160. The best round-trip flight deal from Des Moines to Syracuse found on momondo in the last 72 hours is $329.

The fastest flight from Des Moines to Syracuse takes 4h 38m

There are no direct flights from Des Moines to Syracuse. There are no popular flight routes from Des Moines to Syracuse.

Search flight deals

Frequently asked questions about flying from Des Moines to Syracuse

How far is Des Moines to Syracuse Hancock Intl by plane?
The straight-line distance from Des Moines to Syracuse Hancock Intl is 896.5 mi. 4h 38m is a normal flight duration for this route.
When did momondo last update prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport?
Prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Syracuse Hancock Intl Airport?
The number of operators available for flights from Des Moines Airport to Syracuse Hancock Intl Airport is 3 as of August 2026.
How old do you have to be to fly from Des Moines Airport to Syracuse Hancock Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Syracuse Hancock Intl Airport.
What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?
The travel and health documents you'll need for your trip to Syracuse Hancock Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Syracuse Hancock Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Syracuse?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Des Moines to Syracuse is American Airlines (50% of total bookings). The next most popular airlines are Delta (32%) and United Airlines (18%).

Best airlines flying from Des Moines to Syracuse

Compare and see reviews for airlines that fly from Des Moines to Syracuse with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $258	Free Cancellation	Rating 7.4 10,127 reviews	Search United Airlines flights
American Airlines	PriceFrom $258	Free Cancellation	Rating 7.1 12,008 reviews	Search American Airlines flights
Delta	PriceFrom $258	Free Cancellation	Rating 7.8 8,531 reviews	Search Delta flights

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Why should I use momondo to find a flight deal from Des Moines to Syracuse?

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Can I find flights from Des Moines to Syracuse with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Syracuse from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Syracuse?

momondo provides multiple filters to help you find the best flight to Syracuse from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Syracuse right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Syracuse flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Des Moines to Syracuse from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Syracuse departing on 10/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Des Moines to Syracuse

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How to get the cheapest flight ticket from Des Moines to Syracuse

What is the cheapest month to fly to Syracuse?

Can stopping save me money on Des Moines to Syracuse flights?

What is the cheapest airline that flies from Des Moines to Syracuse Hancock Intl?

What airlines fly to Syracuse?

When to book flights from Des Moines to Syracuse

Cheap Des Moines to Syracuse (DSM to SYR) flight deals and tips

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Frequently asked questions about flying from Des Moines to Syracuse

Best airlines flying from Des Moines to Syracuse

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Why use momondo?

An easier way to manage your Syracuse trip

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