What airlines fly to Syracuse?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Syracuse from Des Moines according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Syracuse. Keep in mind that there are 3 different airlines that fly to Syracuse on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Syracuse Hancock Intl?

United Airlines is the most popular carrier operating from Des Moines to Syracuse Hancock Intl

When did momondo last update prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport?

Prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Syracuse Hancock Intl Airport?

The number of operators available for flights from Des Moines Airport to Syracuse Hancock Intl Airport is 3 as of July 2026.

How old do you have to be to fly from Des Moines Airport to Syracuse Hancock Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Syracuse Hancock Intl Airport.

What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?

The travel and health documents you'll need for your trip to Syracuse Hancock Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Syracuse Hancock Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$304 Cheap Flights from Des Moines to Syracuse in 2026

Q: What is the typical price of a round-trip flight between Des Moines and Syracuse?

Prices are currently low for flights on this route. Typical prices usually range from $388 to $512. The lowest price recently found on this route was $319.

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Syracuse

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:20 pm - 9:32 pm

DSM

SYR

5h 12m

1 stop

6:12 am - 10:26 am

SYR

DSM

5h 14m

1 stop

$319United Airlines

Fri, Aug 14 - Fri, Aug 21

6:00 am - 2:14 pm

DSM

SYR

7h 14m

2 stops

6:15 am - 12:20 pm

SYR

DSM

7h 05m

1 stop

$333United Airlines

Sat, Aug 15 - Sat, Aug 22

1:21 pm - 9:32 pm

DSM

SYR

7h 11m

1 stop

6:00 am - 2:16 pm

SYR

DSM

9h 16m

2 stops

$337United Airlines

Fri, Aug 14 - Fri, Aug 21

5:32 pm - 10:58 pm

DSM

SYR

4h 26m

1 stop

6:21 am - 9:45 am

SYR

DSM

4h 24m

1 stop

$344Delta

Sat, Jul 18 - Wed, Jul 22

6:00 am - 2:14 pm

DSM

SYR

7h 14m

2 stops

6:00 am - 2:16 pm

SYR

DSM

9h 16m

2 stops

$347United Airlines

Sat, Aug 15 - Sat, Aug 22

5:32 pm - 10:58 pm

DSM

SYR

4h 26m

1 stop

6:21 am - 9:45 am

SYR

DSM

4h 24m

1 stop

$369Delta

Sat, Jul 18 - Wed, Jul 22

6:00 am - 2:15 pm

DSM

SYR

7h 15m

2 stops

5:49 pm - 9:22 pm

SYR

DSM

4h 33m

1 stop

$374United Airlines

Sat, Jul 18 - Wed, Jul 22

3:20 pm - 9:32 pm

DSM

SYR

5h 12m

1 stop

6:15 am - 12:20 pm

SYR

DSM

7h 05m

1 stop

$375United Airlines

Sat, Aug 15 - Sat, Aug 22

6:00 am - 11:51 am

DSM

SYR

4h 51m

1 stop

5:35 pm - 12:35 am

SYR

DSM

8h 00m

2 stops

$380American Airlines

Sat, Aug 22 - Sat, Aug 29

6:00 am - 11:50 am

DSM

SYR

4h 50m

1 stop

6:05 am - 9:56 am

SYR

DSM

4h 51m

1 stop

$389American Airlines

Thu, Aug 6 - Sun, Aug 9

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American Airlines flights from Des Moines to Syracuse

Our best American Airlines deals on Des Moines to Syracuse flight tickets

American Airlines

Aug 22

DSM6:00 amDes Moines

4h 51m

1 stop

SYR11:51 amSyracuse Hancock Intl

Aug 29

SYR5:35 pmSyracuse Hancock Intl

8h 00m

2 stops

DSM12:35 amDes Moines

$380

American Airlines

Aug 6

DSM6:00 amDes Moines

4h 50m

1 stop

SYR11:50 amSyracuse Hancock Intl

Aug 9

SYR6:05 amSyracuse Hancock Intl

4h 51m

1 stop

DSM9:56 amDes Moines

$389

American Airlines

Jul 4

DSM6:14 amDes Moines

5h 20m

1 stop

SYR12:34 pmSyracuse Hancock Intl

Jul 11

SYR6:00 amSyracuse Hancock Intl

8h 03m

2 stops

DSM1:03 pmDes Moines

$403

United Airlines flights from Des Moines to Syracuse

Our best United Airlines deals on Des Moines to Syracuse flight tickets

United Airlines

Aug 14

DSM3:20 pmDes Moines

5h 12m

1 stop

SYR9:32 pmSyracuse Hancock Intl

Aug 21

SYR6:12 amSyracuse Hancock Intl

5h 14m

1 stop

DSM10:26 amDes Moines

$319

United Airlines

Aug 15

DSM6:00 amDes Moines

7h 14m

2 stops

SYR2:14 pmSyracuse Hancock Intl

Aug 22

SYR6:15 amSyracuse Hancock Intl

7h 05m

1 stop

DSM12:20 pmDes Moines

$333

United Airlines

Aug 14

DSM1:21 pmDes Moines

7h 11m

1 stop

SYR9:32 pmSyracuse Hancock Intl

Aug 21

SYR6:00 amSyracuse Hancock Intl

9h 16m

2 stops

DSM2:16 pmDes Moines

$337

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Fri 8/14

3:20 pm-9:32 pm

1 stop5h 12m

Syracuse Hancock Intl

Fri 8/21

6:12 am-10:26 am

1 stop5h 14m

$319

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 8/15

6:00 am-2:14 pm

2 stops7h 14m

Syracuse Hancock Intl

Sat 8/22

6:15 am-12:20 pm

1 stop7h 05m

$333

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Fri 8/14

1:21 pm-9:32 pm

1 stop7h 11m

Syracuse Hancock Intl

Fri 8/21

6:00 am-2:16 pm

2 stops9h 16m

$337

Quickest round-trip

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 7/18

5:32 pm-10:58 pm

1 stop4h 26m

Syracuse Hancock Intl

Wed 7/22

6:21 am-9:45 am

1 stop4h 24m

$344

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 8/15

6:00 am-2:14 pm

2 stops7h 14m

Syracuse Hancock Intl

Sat 8/22

6:00 am-2:16 pm

2 stops9h 16m

$347

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 7/18

5:32 pm-10:58 pm

1 stop4h 26m

Syracuse Hancock Intl

Wed 7/22

6:21 am-9:45 am

1 stop4h 24m

$369

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 7/18

6:00 am-2:15 pm

2 stops7h 15m

Syracuse Hancock Intl

Wed 7/22

5:49 pm-9:22 pm

1 stop4h 33m

$374

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 8/15

3:20 pm-9:32 pm

1 stop5h 12m

Syracuse Hancock Intl

Sat 8/22

6:15 am-12:20 pm

1 stop7h 05m

$375

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 8/22

6:00 am-11:51 am

1 stop4h 51m

Syracuse Hancock Intl

Sat 8/29

5:35 pm-12:35 am

2 stops8h 00m

$380

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Thu 8/6

6:00 am-11:50 am

1 stop4h 50m

Syracuse Hancock Intl

Sun 8/9

6:05 am-9:56 am

1 stop4h 51m

$389

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Syracuse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Des Moines and Syracuse?

What is the cheapest month to fly to Syracuse?

The month of September is, on average, the cheapest month to fly to Syracuse from Des Moines, with most prices found around $258. If you aren’t able to travel to Syracuse during the month of September, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $273.

Can stopping save me money on Des Moines to Syracuse flights?

You could potentially save up to 75% on your flight if you consider stops on a Des Moines to Syracuse flight.

When to book flights from Des Moines to Syracuse

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Syracuse according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Syracuse (DSM to SYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Syracuse

Fastest flight time	4h 25m
Direct flights	None

The fastest flight from Des Moines to Syracuse takes 4h 25m

There are no direct flights from Des Moines to Syracuse. There are no popular flight routes from Des Moines to Syracuse.

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Frequently asked questions about flying from Des Moines to Syracuse

How far is Des Moines to Syracuse Hancock Intl by plane?
The straight-line distance from Des Moines to Syracuse Hancock Intl is 896.5 mi. 4h 25m is a normal flight duration for this route.
When did momondo last update prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport?
Prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Syracuse Hancock Intl Airport?
The number of operators available for flights from Des Moines Airport to Syracuse Hancock Intl Airport is 3 as of July 2026.
How old do you have to be to fly from Des Moines Airport to Syracuse Hancock Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Syracuse Hancock Intl Airport.
What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?
The travel and health documents you'll need for your trip to Syracuse Hancock Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Syracuse Hancock Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Syracuse?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Des Moines to Syracuse is American Airlines (50% of total bookings). The next most popular airlines are Delta (36%) and United Airlines (14%).

Best airlines flying from Des Moines to Syracuse

Compare and see reviews for airlines that fly from Des Moines to Syracuse with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $258	Free Cancellation	Rating 7.4 9,927 reviews	Search United Airlines flights
American Airlines	PriceFrom $258	Free Cancellation	Rating 7.1 11,764 reviews	Search American Airlines flights
Delta	PriceFrom $258	Free Cancellation	Rating 7.8 8,453 reviews	Search Delta flights

Liverpool

Skaneateles

Oswego

East Syracuse

Auburn

Seneca Falls

Waterloo

Cicero

Bridgeport

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Syracuse?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Syracuse. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Syracuse with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Syracuse from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Syracuse?

momondo provides multiple filters to help you find the best flight to Syracuse from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Syracuse right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Syracuse flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Des Moines to Syracuse from $304

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Syracuse departing on 10/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Des Moines to Syracuse

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How to get the cheapest flight ticket from Des Moines to Syracuse

What is the typical price of a round-trip flight between Des Moines and Syracuse?

What is the cheapest month to fly to Syracuse?

Can stopping save me money on Des Moines to Syracuse flights?

What is the cheapest airline that flies from Des Moines to Syracuse Hancock Intl?

What airlines fly to Syracuse?

When to book flights from Des Moines to Syracuse

Cheap Des Moines to Syracuse (DSM to SYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Syracuse

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An easier way to manage your Syracuse trip

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