What airlines fly to Syracuse?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Syracuse from Des Moines according to our data. Delta is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Syracuse. Keep in mind that there are 3 different airlines that fly to Syracuse on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Syracuse Hancock Intl?

United Airlines and Delta are the most popular carriers operating from Des Moines to Syracuse Hancock Intl

When did momondo last update prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport?

Prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Syracuse Hancock Intl Airport?

The number of operators available for flights from Des Moines Airport to Syracuse Hancock Intl Airport is 2 as of August 2025.

How old do you have to be to fly from Des Moines Airport to Syracuse Hancock Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Syracuse Hancock Intl Airport.

What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?

The travel and health documents you'll need for your trip to Syracuse Hancock Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Syracuse Hancock Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$128 Cheap Flights from Des Moines to Syracuse in 2025

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Find the cheapest flights from Des Moines to Syracuse

Round-trip

One-way

Last minute

Cheap round-trip flights

3:15 pm - 11:06 pmDSM-SYR

6h 51m1 stop

12:17 pm - 7:20 pmSYR-DSM

8h 03m1 stop

$259Delta

Find Deal

Wed, Oct 8 - Wed, Oct 15

3:56 pm - 11:38 pmDSM-SYR

6h 42m1 stop

4:45 pm - 8:11 pmSYR-DSM

4h 26m1 stop

$260American Airlines

Find Deal

Wed, Oct 8 - Wed, Oct 15

6:07 pm - 11:29 pmDSM-SYR

4h 22m1 stop

12:45 pm - 8:11 pmSYR-DSM

8h 26m2 stops

$266American Airlines

Find Deal

Wed, Oct 8 - Wed, Oct 15

5:42 pm - 11:22 pmDSM-SYR

4h 40m1 stop

12:45 pm - 8:11 pmSYR-DSM

8h 26m2 stops

$267American Airlines

Find Deal

Wed, Oct 8 - Wed, Oct 15

1:05 pm - 9:02 pmDSM-SYR

6h 57m1 stop

6:00 am - 2:19 pmSYR-DSM

9h 19m2 stops

$303United Airlines

Find Deal

Thu, Nov 20 - Mon, Nov 24

3:15 pm - 11:06 pmDSM-SYR

6h 51m1 stop

6:00 am - 1:28 pmSYR-DSM

8h 28m1 stop

$319Delta

Find Deal

Thu, Oct 30 - Mon, Nov 3

5:52 pm - 11:10 pmDSM-SYR

4h 18m1 stop

6:08 am - 1:33 pmSYR-DSM

8h 25m1 stop

$329Delta

Find Deal

Sun, Nov 23 - Sun, Nov 30

6:30 am - 2:14 pmDSM-SYR

6h 44m2 stops

6:15 am - 10:32 amSYR-DSM

5h 17m1 stop

$336United Airlines

Find Deal

Thu, Sep 25 - Sun, Sep 28

4:03 pm - 7:37 pmDSM-SYR

26h 34m1 stop

6:16 pm - 10:12 amSYR-DSM

16h 56m1 stop

$519Allegiant Air

Find Deal

Tue, Nov 25 - Sun, Nov 30

9:34 am - 9:28 amDSM-SYR

22h 54m1 stop

6:16 pm - 10:12 amSYR-DSM

16h 56m1 stop

$543Allegiant Air

Find Deal

Mon, Nov 24 - Sun, Nov 30

American Airlines flights from Des Moines to Syracuse

Our best American Airlines deals on Des Moines to Syracuse flight tickets

American Airlines

Oct 8

DSM3:56 pmDes Moines

6h 42m

1 stop

SYR11:38 pmSyracuse Hancock Intl

Oct 15

SYR4:45 pmSyracuse Hancock Intl

4h 26m

1 stop

DSM8:11 pmDes Moines

$260

Find similar

American Airlines

Oct 8

DSM6:07 pmDes Moines

4h 22m

1 stop

SYR11:29 pmSyracuse Hancock Intl

Oct 15

SYR12:45 pmSyracuse Hancock Intl

8h 26m

2 stops

DSM8:11 pmDes Moines

$266

Find similar

American Airlines

Oct 8

DSM5:42 pmDes Moines

4h 40m

1 stop

SYR11:22 pmSyracuse Hancock Intl

Oct 15

SYR12:45 pmSyracuse Hancock Intl

8h 26m

2 stops

DSM8:11 pmDes Moines

$267

Find similar

United Airlines flights from Des Moines to Syracuse

Our best United Airlines deals on Des Moines to Syracuse flight tickets

United Airlines

Nov 20

DSM1:05 pmDes Moines

6h 57m

1 stop

SYR9:02 pmSyracuse Hancock Intl

Nov 24

SYR6:00 amSyracuse Hancock Intl

9h 19m

2 stops

DSM2:19 pmDes Moines

$303

Find similar

United Airlines

Sep 25

DSM6:30 amDes Moines

6h 44m

2 stops

SYR2:14 pmSyracuse Hancock Intl

Sep 28

SYR6:15 amSyracuse Hancock Intl

5h 17m

1 stop

DSM10:32 amDes Moines

$336

Find similar

United Airlines

Sep 26

DSM3:25 pmDes Moines

5h 03m

1 stop

SYR9:28 pmSyracuse Hancock Intl

Sep 28

SYR6:15 amSyracuse Hancock Intl

5h 17m

1 stop

DSM10:32 amDes Moines

$368

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Wed 10/8

3:15 pm-11:06 pm

1 stop6h 51m

Syracuse Hancock Intl

Wed 10/15

12:17 pm-7:20 pm

1 stop8h 03m

$259

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Wed 10/8

3:56 pm-11:38 pm

1 stop6h 42m

Syracuse Hancock Intl

Wed 10/15

4:45 pm-8:11 pm

1 stop4h 26m

$260

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Wed 10/8

6:07 pm-11:29 pm

1 stop4h 22m

Syracuse Hancock Intl

Wed 10/15

12:45 pm-8:11 pm

2 stops8h 26m

$266

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Wed 10/8

5:42 pm-11:22 pm

1 stop4h 40m

Syracuse Hancock Intl

Wed 10/15

12:45 pm-8:11 pm

2 stops8h 26m

$267

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Thu 11/20

1:05 pm-9:02 pm

1 stop6h 57m

Syracuse Hancock Intl

Mon 11/24

6:00 am-2:19 pm

2 stops9h 19m

$303

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Thu 10/30

3:15 pm-11:06 pm

1 stop6h 51m

Syracuse Hancock Intl

Mon 11/3

6:00 am-1:28 pm

1 stop8h 28m

$319

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sun 11/23

5:52 pm-11:10 pm

1 stop4h 18m

Syracuse Hancock Intl

Sun 11/30

6:08 am-1:33 pm

1 stop8h 25m

$329

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Thu 9/25

6:30 am-2:14 pm

2 stops6h 44m

Syracuse Hancock Intl

Sun 9/28

6:15 am-10:32 am

1 stop5h 17m

$336

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Tue 11/25

4:03 pm-7:37 pm

1 stop26h 34m

Syracuse Hancock Intl

Sun 11/30

6:16 pm-10:12 am

1 stop16h 56m

$519

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Mon 11/24

9:34 am-9:28 am

1 stop22h 54m

Syracuse Hancock Intl

Sun 11/30

6:16 pm-10:12 am

1 stop16h 56m

$543

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Des Moines to Syracuse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Syracuse?

The month of April is, on average, the cheapest month to fly to Syracuse from Des Moines, with most prices found around $272. If you aren’t able to travel to Syracuse during the month of April, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $286.

What is the cheapest day to depart on your flight to Syracuse?

The cheapest day to depart from Des Moines to Syracuse is on a Wednesday. Travelers who choose to depart for Syracuse on a Wednesday will often find tickets for as low as $257. The most expensive day to fly to Syracuse is Sunday, with ticket prices averaging around $567.

What is the cheapest time of day to depart on your flight to Syracuse?

Our most recent data shows that the best time of day to fly to Syracuse is in the morning. Flights from Des Moines to Syracuse during this time can be as low as $347. Flights to Syracuse are more costly in the afternoon, with an average ticket price of $458. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Des Moines to Syracuse

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Syracuse according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Syracuse (DSM to SYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Syracuse

Direct flights	None

There are no direct flights from Des Moines to Syracuse. There are no popular flight routes from Des Moines to Syracuse.

Search flight deals

How far is Des Moines to Syracuse Hancock Intl by plane?
The straight-line distance from Des Moines to Syracuse Hancock Intl is 896.5 mi. 4h 18m is a normal flight duration for this route.
When did momondo last update prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport?
Prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Syracuse Hancock Intl Airport?
The number of operators available for flights from Des Moines Airport to Syracuse Hancock Intl Airport is 2 as of August 2025.
How old do you have to be to fly from Des Moines Airport to Syracuse Hancock Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Syracuse Hancock Intl Airport.
What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?
The travel and health documents you'll need for your trip to Syracuse Hancock Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Syracuse Hancock Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Syracuse?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Des Moines to Syracuse is American Airlines (60% of total bookings). The next most popular airline is Delta (40%).

Best airlines flying from Des Moines to Syracuse

Compare and see reviews for airlines that fly from Des Moines to Syracuse with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $236	Free Cancellation	Rating 7.9 7,981 reviews		Search Delta flights
American Airlines	PriceFrom $250	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights

Skaneateles

Oswego

Liverpool

Auburn

East Syracuse

Seneca Falls

Waterloo

Cicero

Bridgeport

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Why should I use momondo to find a flight deal from Des Moines to Syracuse?

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Can I find flights from Des Moines to Syracuse with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Syracuse from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Syracuse?

momondo provides multiple filters to help you find the best flight to Syracuse from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Syracuse right now. Can momondo alert me if prices change?

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Cheap flights from Des Moines to Syracuse from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Syracuse departing on 9/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Des Moines to Syracuse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Syracuse?

What is the cheapest day to depart on your flight to Syracuse?

The cheapest day to depart from Des Moines to Syracuse is on a Wednesday. Travelers who choose to depart for Syracuse on a Wednesday will often find tickets for as low as $257. The most expensive day to fly to Syracuse is Sunday, with ticket prices averaging around $567.

What is the cheapest time of day to depart on your flight to Syracuse?

What is the cheapest airline that flies from Des Moines to Syracuse Hancock Intl?

United Airlines and Delta are the most popular carriers operating from Des Moines to Syracuse Hancock Intl

What airlines fly to Syracuse?

When to book flights from Des Moines to Syracuse

Cheap Des Moines to Syracuse (DSM to SYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Syracuse

Direct flights

How far is Des Moines to Syracuse Hancock Intl by plane?

When did momondo last update prices for flights from Des Moines Airport to Syracuse Hancock Intl Airport?

How many operators does momondo search for flights from Des Moines Airport to Syracuse Hancock Intl Airport?

How old do you have to be to fly from Des Moines Airport to Syracuse Hancock Intl Airport?

What documentation or ID do you need to fly to Syracuse Hancock Intl Airport?

What is the most popular airline from Des Moines to Syracuse?

Best airlines flying from Des Moines to Syracuse

Compare and see reviews for airlines that fly from Des Moines to Syracuse with momondo

Traveling to a place near Syracuse?

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Syracuse?

Can I find flights from Des Moines to Syracuse with flexible booking policies on momondo?

How can momondo help me find flights from Des Moines to Syracuse?

I’m not ready to book a flight from Des Moines to Syracuse right now. Can momondo alert me if prices change?

An easier way to manage your Syracuse trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing New York