What is the cheapest airline that flies from Des Moines to South America?

Avianca, LATAM Airlines, and American Airlines are the most popular carriers operating from Des Moines to South America

When did momondo last update prices for flights from Des Moines Airport to South America?

Prices for flights from Des Moines Airport to South America were last updated today.

How many operators does momondo search for flights from Des Moines Airport to South America?

As of February 2026, there are 4 operators available to choose from for flights from Des Moines Airport to South America.

How old do you have to be to fly from Des Moines Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$253 Cheap Flights from Des Moines to South America in 2026

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Find the cheapest flights from Des Moines to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:20 am - 3:30 am

DSM

LIM

19h 10m

2 stops

3:05 am - 10:43 pm

LIM

DSM

19h 38m

2 stops

$484Multiple Airlines

Tue, Mar 31 - Mon, Apr 6

6:59 pm - 10:35 am

DSM

LIM

15h 36m

2 stops

3:05 am - 10:43 pm

LIM

DSM

19h 38m

2 stops

$491Multiple Airlines

Sat, Apr 11 - Fri, Apr 17

7:27 pm - 12:39 pm

DSM

BAQ

17h 12m

2 stops

3:25 pm - 11:38 am

BAQ

DSM

20h 13m

2 stops

$560American Airlines

Mon, Mar 30 - Mon, Apr 6

7:27 pm - 2:25 pm

DSM

BAQ

18h 58m

2 stops

1:30 pm - 1:07 pm

BAQ

DSM

23h 37m

2 stops

$568American Airlines

Thu, Mar 19 - Thu, Mar 26

5:35 am - 1:15 pm

DSM

CTG

7h 40m

1 stop

2:30 pm - 10:38 pm

CTG

DSM

8h 08m

1 stop

$627Delta

Wed, Apr 1 - Wed, Apr 8

5:35 am - 1:15 pm

DSM

CTG

7h 40m

1 stop

2:30 pm - 10:38 pm

CTG

DSM

8h 08m

1 stop

$628LATAM Airlines

Tue, Mar 31 - Tue, Apr 7

5:35 am - 1:15 pm

DSM

CTG

7h 40m

1 stop

2:30 pm - 10:48 am

CTG

DSM

20h 18m

1 stop

$643LATAM Airlines

Tue, Mar 31 - Tue, Apr 7

6:20 am - 11:25 pm

DSM

UIO

17h 05m

2 stops

12:35 am - 10:43 pm

UIO

DSM

22h 08m

1 stop

$671United Airlines

Tue, Mar 31 - Mon, Apr 6

6:20 am - 11:25 pm

DSM

UIO

17h 05m

2 stops

12:35 am - 9:27 pm

UIO

DSM

20h 52m

2 stops

$685United Airlines

Wed, Apr 1 - Tue, Apr 7

2:39 pm - 5:00 am

DSM

LIM

14h 21m

2 stops

12:15 am - 5:53 pm

LIM

DSM

17h 38m

2 stops

$758Delta

Sun, May 10 - Wed, May 27

Delta flights from Des Moines to South America

Our best Delta deals on Des Moines to South America flight tickets

Delta

Apr 1

DSM5:35 amDes Moines

7h 40m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Apr 8

CTG2:30 pmCartagena Rafael Nunez

8h 08m

1 stop

DSM10:38 pmDes Moines

$627

Delta

Mar 31

DSM5:35 amDes Moines

7h 40m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Apr 7

CTG2:30 pmCartagena Rafael Nunez

8h 08m

1 stop

DSM10:38 pmDes Moines

$678

Delta

Mar 31

DSM5:35 amDes Moines

13h 24m

1 stop

UIO6:59 pmQuito Mariscal Sucr

Apr 6

UIO12:59 amQuito Mariscal Sucr

15h 34m

1 stop

DSM4:33 pmDes Moines

$712

LATAM Airlines flights from Des Moines to South America

Our best LATAM Airlines deals on Des Moines to South America flight tickets

LATAM Airlines

Mar 31

DSM5:35 amDes Moines

7h 40m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Apr 7

CTG2:30 pmCartagena Rafael Nunez

8h 08m

1 stop

DSM10:38 pmDes Moines

$628

LATAM Airlines

Mar 31

DSM5:35 amDes Moines

7h 40m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Apr 7

CTG2:30 pmCartagena Rafael Nunez

20h 18m

1 stop

DSM10:48 amDes Moines

$643

LATAM Airlines

Mar 30

DSM5:35 amDes Moines

7h 40m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Apr 6

CTG2:30 pmCartagena Rafael Nunez

20h 18m

1 stop

DSM10:48 amDes Moines

$661

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Tue 3/31

8:20 am-3:30 am

2 stops19h 10m

Lima J Chavez Intl

Mon 4/6

3:05 am-10:43 pm

2 stops19h 38m

$484

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Sat 4/11

6:59 pm-10:35 am

2 stops15h 36m

Lima J Chavez Intl

Fri 4/17

3:05 am-10:43 pm

2 stops19h 38m

$491

Des MoinesBarranquilla

DSM - BAQ

DSMBAQ

Des Moines

Mon 3/30

7:27 pm-12:39 pm

2 stops17h 12m

Barranquilla E Cortissoz

Mon 4/6

3:25 pm-11:38 am

2 stops20h 13m

$560

Des MoinesBarranquilla

DSM - BAQ

DSMBAQ

Des Moines

Thu 3/19

7:27 pm-2:25 pm

2 stops18h 58m

Barranquilla E Cortissoz

Thu 3/26

1:30 pm-1:07 pm

2 stops23h 37m

$568

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Wed 4/1

5:35 am-1:15 pm

1 stop7h 40m

Cartagena Rafael Nunez

Wed 4/8

2:30 pm-10:38 pm

1 stop8h 08m

$627

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Tue 3/31

5:35 am-1:15 pm

1 stop7h 40m

Cartagena Rafael Nunez

Tue 4/7

2:30 pm-10:38 pm

1 stop8h 08m

$628

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Tue 3/31

5:35 am-1:15 pm

1 stop7h 40m

Cartagena Rafael Nunez

Tue 4/7

2:30 pm-10:48 am

1 stop20h 18m

$643

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Tue 3/31

6:20 am-11:25 pm

2 stops17h 05m

Quito Mariscal Sucr

Mon 4/6

12:35 am-10:43 pm

1 stop22h 08m

$671

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Wed 4/1

6:20 am-11:25 pm

2 stops17h 05m

Quito Mariscal Sucr

Tue 4/7

12:35 am-9:27 pm

2 stops20h 52m

$685

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Sun 5/10

2:39 pm-5:00 am

2 stops14h 21m

Lima J Chavez Intl

Wed 5/27

12:15 am-5:53 pm

2 stops17h 38m

$758

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Des Moines to South America flights?

You could potentially save up to 9% on your flight if you consider stops on a Des Moines to South America flight.

Cheap Des Moines to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to South America

Fastest flight time	13h 14m
Direct flights	None

The fastest flight from Des Moines to South America takes 13h 14m

There are no direct flights from Des Moines to South America. There are no popular flight routes from Des Moines to South America.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to South America?
Prices for flights from Des Moines Airport to South America were last updated today.
How many operators does momondo search for flights from Des Moines Airport to South America?
As of February 2026, there are 4 operators available to choose from for flights from Des Moines Airport to South America.
How old do you have to be to fly from Des Moines Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to South America

Compare and see reviews for airlines that fly from Des Moines to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $503	Free Cancellation	Rating 7.9 8,205 reviews		Search Delta flights
LATAM Airlines	PriceFrom $634	Free Cancellation	Rating 7.5 1,921 reviews		Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Des Moines with this policy.

How can momondo help me find flights from Des Moines to South America?

momondo helps you find the best flight between Des Moines and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.