What is the cheapest airline that flies from Des Moines to South America?

Avianca, Copa Airlines, and United Airlines are the most popular carriers operating from Des Moines to South America

When did momondo last update prices for flights from Des Moines Airport to South America?

Prices for flights from Des Moines Airport to South America were last updated today.

How many operators does momondo search for flights from Des Moines Airport to South America?

As of July 2026, there are 3 operators available to choose from for flights from Des Moines Airport to South America.

How old do you have to be to fly from Des Moines Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$292 Cheap Flights from Des Moines to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:45 am - 12:34 pm

DSM

BAQ

29h 49m

1 stop

1:34 pm - 11:25 pm

BAQ

DSM

9h 51m

1 stop

$650American Airlines

Sat, Aug 15 - Sat, Aug 22

6:45 am - 12:35 pm

DSM

CTG

29h 50m

1 stop

1:35 pm - 11:25 pm

CTG

DSM

9h 50m

1 stop

$653American Airlines

Sat, Aug 15 - Sat, Aug 22

6:00 am - 11:25 pm

DSM

UIO

17h 25m

1 stop

12:35 am - 5:23 pm

UIO

DSM

16h 48m

2 stops

$720United Airlines

Thu, Oct 22 - Tue, Oct 27

6:00 am - 11:25 pm

DSM

UIO

17h 25m

1 stop

12:35 am - 10:25 pm

UIO

DSM

21h 50m

1 stop

$726United Airlines

Thu, Oct 22 - Tue, Oct 27

6:54 pm - 6:59 pm

DSM

UIO

24h 05m

1 stop

11:55 pm - 6:09 pm

UIO

DSM

18h 14m

1 stop

$731Delta

Thu, Oct 22 - Wed, Oct 28

5:40 am - 1:15 pm

DSM

CTG

7h 35m

1 stop

2:30 pm - 10:43 am

CTG

DSM

20h 13m

1 stop

$738LATAM Airlines

Thu, Aug 13 - Thu, Aug 20

3:20 pm - 8:55 am

DSM

GYE

17h 35m

2 stops

10:05 am - 10:26 am

GYE

DSM

24h 21m

2 stops

$766Multiple Airlines

Thu, Aug 13 - Thu, Aug 20

5:40 am - 1:15 pm

DSM

CTG

7h 35m

1 stop

2:30 pm - 10:43 am

CTG

DSM

20h 13m

1 stop

$777LATAM Airlines

Thu, Aug 13 - Thu, Aug 20

6:06 pm - 6:59 pm

DSM

UIO

24h 53m

2 stops

12:59 am - 3:16 pm

UIO

DSM

14h 17m

1 stop

$778Delta

Sat, Aug 15 - Fri, Aug 21

6:52 pm - 10:45 am

DSM

LIM

14h 53m

2 stops

3:00 am - 10:25 pm

LIM

DSM

20h 25m

2 stops

$829Multiple Airlines

Sat, Nov 7 - Fri, Nov 13

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Delta flights from Des Moines to South America

Our best Delta deals on Des Moines to South America flight tickets

Delta

Oct 22

DSM6:54 pmDes Moines

24h 05m

1 stop

UIO6:59 pmQuito Mariscal Sucr

Oct 28

UIO11:55 pmQuito Mariscal Sucr

18h 14m

1 stop

DSM6:09 pmDes Moines

$731

Delta

Aug 15

DSM6:06 pmDes Moines

24h 53m

2 stops

UIO6:59 pmQuito Mariscal Sucr

Aug 21

UIO12:59 amQuito Mariscal Sucr

14h 17m

1 stop

DSM3:16 pmDes Moines

$778

Delta

Aug 15

DSM4:11 pmDes Moines

26h 48m

1 stop

UIO6:59 pmQuito Mariscal Sucr

Aug 21

UIO12:59 amQuito Mariscal Sucr

9h 44m

1 stop

DSM10:43 amDes Moines

$779

LATAM Airlines flights from Des Moines to South America

Our best LATAM Airlines deals on Des Moines to South America flight tickets

LATAM Airlines

Aug 13

DSM5:40 amDes Moines

7h 35m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Aug 20

CTG2:30 pmCartagena Rafael Nunez

20h 13m

1 stop

DSM10:43 amDes Moines

$738

LATAM Airlines

Aug 13

DSM5:40 amDes Moines

7h 35m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Aug 20

CTG2:30 pmCartagena Rafael Nunez

20h 13m

1 stop

DSM10:43 amDes Moines

$777

LATAM Airlines

Oct 19

DSM5:40 amDes Moines

12h 50m

2 stops

BAQ6:30 pmBarranquilla E Cortissoz

Oct 22

BAQ4:35 amBarranquilla E Cortissoz

17h 59m

2 stops

DSM10:34 pmDes Moines

$785

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesBarranquilla

DSM - BAQ

DSMBAQ

Des Moines

Sat 8/15

6:45 am-12:34 pm

1 stop29h 49m

Barranquilla E Cortissoz

Sat 8/22

1:34 pm-11:25 pm

1 stop9h 51m

$650

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Sat 8/15

6:45 am-12:35 pm

1 stop29h 50m

Cartagena Rafael Nunez

Sat 8/22

1:35 pm-11:25 pm

1 stop9h 50m

$653

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Thu 10/22

6:00 am-11:25 pm

1 stop17h 25m

Quito Mariscal Sucr

Tue 10/27

12:35 am-5:23 pm

2 stops16h 48m

$720

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Thu 10/22

6:00 am-11:25 pm

1 stop17h 25m

Quito Mariscal Sucr

Tue 10/27

12:35 am-10:25 pm

1 stop21h 50m

$726

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Thu 10/22

6:54 pm-6:59 pm

1 stop24h 05m

Quito Mariscal Sucr

Wed 10/28

11:55 pm-6:09 pm

1 stop18h 14m

$731

Quickest round-trip

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Thu 8/13

5:40 am-1:15 pm

1 stop7h 35m

Cartagena Rafael Nunez

Thu 8/20

2:30 pm-10:43 am

1 stop20h 13m

$738

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Thu 8/13

3:20 pm-8:55 am

2 stops17h 35m

Guayaquil Jose Joaquin de Olmedo

Thu 8/20

10:05 am-10:26 am

2 stops24h 21m

$766

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Thu 8/13

5:40 am-1:15 pm

1 stop7h 35m

Cartagena Rafael Nunez

Thu 8/20

2:30 pm-10:43 am

1 stop20h 13m

$777

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Sat 8/15

6:06 pm-6:59 pm

2 stops24h 53m

Quito Mariscal Sucr

Fri 8/21

12:59 am-3:16 pm

1 stop14h 17m

$778

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Sat 11/7

6:52 pm-10:45 am

2 stops14h 53m

Lima J Chavez Intl

Fri 11/13

3:00 am-10:25 pm

2 stops20h 25m

$829

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, August is the cheapest month to fly from Des Moines to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $489. If you aren’t able to travel during the month of August, then book flights to South America from Des Moines during February instead. Flights to South America in February, while not as cheap as those in August, still average around $638.

Can stopping save me money on Des Moines to South America flights?

You could potentially save up to 21% on your flight if you consider stops on a Des Moines to South America flight.

Cheap Des Moines to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to South America

Fastest flight time	8h 24m
Direct flights	None

The fastest flight from Des Moines to South America takes 8h 24m

There are no direct flights from Des Moines to South America. There are no popular flight routes from Des Moines to South America.

Search flight deals

Frequently asked questions about flying from Des Moines to South America

When did momondo last update prices for flights from Des Moines Airport to South America?
Prices for flights from Des Moines Airport to South America were last updated today.
How many operators does momondo search for flights from Des Moines Airport to South America?
As of July 2026, there are 3 operators available to choose from for flights from Des Moines Airport to South America.
How old do you have to be to fly from Des Moines Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to South America

Compare and see reviews for airlines that fly from Des Moines to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $607	Free Cancellation	Rating 7.8 8,452 reviews		Search Delta flights
LATAM Airlines	PriceFrom $688	Free Cancellation	Rating 7.4 1,946 reviews		Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Des Moines with this policy.

How can momondo help me find flights from Des Moines to South America?

momondo helps you find the best flight between Des Moines and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.