What is the cheapest airline that flies from Des Moines to Santa Fe?

United Airlines and American Airlines are the most popular carriers operating from Des Moines to Santa Fe

What airlines fly to Santa Fe?

United Airlines, American Airlines and Southwest are the top three most popular airlines that fly to Santa Fe from Des Moines according to our data. United Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Santa Fe. Keep in mind that there are 3 different airlines that fly to Santa Fe on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Santa Fe Airport?

Prices for flights from Des Moines Airport to Santa Fe Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Santa Fe Airport?

The number of operators available for flights from Des Moines Airport to Santa Fe Airport is 1 as of February 2026.

How old do you have to be to fly from Des Moines Airport to Santa Fe Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Fe Airport.

What documentation or ID do you need to fly to Santa Fe Airport?

The necessary travel and health documents for your Santa Fe Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$244 Cheap Flights from Des Moines to Santa Fe in 2026

Q: What is the typical price of a round-trip flight between Des Moines and Santa Fe?

Prices are currently low for flights on this route. Typical prices usually range from $549 to $663. The lowest price recently found on this route was $264.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Des Moines to Santa Fe

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:30 am - 9:09 am

DSM

SAF

4h 39m

1 stop

10:30 am - 4:10 pm

SAF

DSM

4h 40m

1 stop

$264United Airlines

Sat, Apr 18 - Tue, Apr 21

5:00 am - 10:07 am

DSM

SAF

6h 07m

1 stop

11:56 am - 11:49 pm

SAF

DSM

10h 53m

2 stops

$274American Airlines

Tue, Apr 21 - Sat, Apr 25

5:00 am - 10:07 am

DSM

SAF

6h 07m

1 stop

11:56 am - 11:49 pm

SAF

DSM

10h 53m

2 stops

$309American Airlines

Sat, Apr 18 - Tue, Apr 21

6:00 am - 5:56 pm

DSM

SAF

12h 56m

2 stops

11:56 am - 11:49 pm

SAF

DSM

10h 53m

2 stops

$314American Airlines

Sat, May 16 - Tue, May 19

1:29 pm - 5:08 pm

DSM

SAF

4h 39m

1 stop

6:00 pm - 11:43 pm

SAF

DSM

4h 43m

1 stop

$319United Airlines

Sat, Feb 21 - Fri, Feb 27

5:30 am - 9:34 am

DSM

SAF

5h 04m

1 stop

5:49 pm - 11:44 pm

SAF

DSM

4h 55m

1 stop

$348United Airlines

Sat, May 16 - Tue, May 19

5:50 am - 9:41 am

DSM

SAF

4h 51m

1 stop

10:30 am - 4:10 pm

SAF

DSM

4h 40m

1 stop

$357United Airlines

Wed, May 27 - Sat, May 30

5:00 am - 10:07 am

DSM

SAF

6h 07m

1 stop

4:09 pm - 11:59 pm

SAF

DSM

6h 50m

1 stop

$375American Airlines

Tue, Apr 21 - Sat, Apr 25

5:30 am - 9:08 am

DSM

SAF

4h 38m

1 stop

5:53 pm - 11:42 pm

SAF

DSM

4h 49m

1 stop

$384United Airlines

Thu, Mar 19 - Thu, Mar 26

5:00 am - 10:07 am

DSM

SAF

6h 07m

1 stop

11:56 am - 11:49 pm

SAF

DSM

10h 53m

2 stops

$385American Airlines

Wed, Apr 22 - Thu, Apr 30

United Airlines flights from Des Moines to Santa Fe

Our best United Airlines deals on Des Moines to Santa Fe flight tickets

United Airlines

Apr 18

DSM5:30 amDes Moines

4h 39m

1 stop

SAF9:09 amSanta Fe

Apr 21

SAF10:30 amSanta Fe

4h 40m

1 stop

DSM4:10 pmDes Moines

$264

United Airlines

Feb 21

DSM1:29 pmDes Moines

4h 39m

1 stop

SAF5:08 pmSanta Fe

Feb 27

SAF6:00 pmSanta Fe

4h 43m

1 stop

DSM11:43 pmDes Moines

$319

United Airlines

May 16

DSM5:30 amDes Moines

5h 04m

1 stop

SAF9:34 amSanta Fe

May 19

SAF5:49 pmSanta Fe

4h 55m

1 stop

DSM11:44 pmDes Moines

$348

American Airlines flights from Des Moines to Santa Fe

Our best American Airlines deals on Des Moines to Santa Fe flight tickets

American Airlines

Apr 21

DSM5:00 amDes Moines

6h 07m

1 stop

SAF10:07 amSanta Fe

Apr 25

SAF11:56 amSanta Fe

10h 53m

2 stops

DSM11:49 pmDes Moines

$274

American Airlines

Apr 18

DSM5:00 amDes Moines

6h 07m

1 stop

SAF10:07 amSanta Fe

Apr 21

SAF11:56 amSanta Fe

10h 53m

2 stops

DSM11:49 pmDes Moines

$309

American Airlines

May 16

DSM6:00 amDes Moines

12h 56m

2 stops

SAF5:56 pmSanta Fe

May 19

SAF11:56 amSanta Fe

10h 53m

2 stops

DSM11:49 pmDes Moines

$314

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 4/18

5:30 am-9:09 am

1 stop4h 39m

Santa Fe

Tue 4/21

10:30 am-4:10 pm

1 stop4h 40m

$264

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Tue 4/21

5:00 am-10:07 am

1 stop6h 07m

Santa Fe

Sat 4/25

11:56 am-11:49 pm

2 stops10h 53m

$274

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 4/18

5:00 am-10:07 am

1 stop6h 07m

Santa Fe

Tue 4/21

11:56 am-11:49 pm

2 stops10h 53m

$309

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 5/16

6:00 am-5:56 pm

2 stops12h 56m

Santa Fe

Tue 5/19

11:56 am-11:49 pm

2 stops10h 53m

$314

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 2/21

1:29 pm-5:08 pm

1 stop4h 39m

Santa Fe

Fri 2/27

6:00 pm-11:43 pm

1 stop4h 43m

$319

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 5/16

5:30 am-9:34 am

1 stop5h 04m

Santa Fe

Tue 5/19

5:49 pm-11:44 pm

1 stop4h 55m

$348

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Wed 5/27

5:50 am-9:41 am

1 stop4h 51m

Santa Fe

Sat 5/30

10:30 am-4:10 pm

1 stop4h 40m

$357

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Tue 4/21

5:00 am-10:07 am

1 stop6h 07m

Santa Fe

Sat 4/25

4:09 pm-11:59 pm

1 stop6h 50m

$375

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Thu 3/19

5:30 am-9:08 am

1 stop4h 38m

Santa Fe

Thu 3/26

5:53 pm-11:42 pm

1 stop4h 49m

$384

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Wed 4/22

5:00 am-10:07 am

1 stop6h 07m

Santa Fe

Thu 4/30

11:56 am-11:49 pm

2 stops10h 53m

$385

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Des Moines and Santa Fe?

When to book flights from Des Moines to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Santa Fe (DSM to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santa Fe

Fastest flight time	4h 29m
Direct flights	None

The fastest flight from Des Moines to Santa Fe takes 4h 29m

There are no direct flights from Des Moines to Santa Fe. There are no popular flight routes from Des Moines to Santa Fe.

Search flight deals

How far is Des Moines to Santa Fe by plane?
There are 777.7 mi between Des Moines and Santa Fe. A reasonable flight in good conditions will take 4h 29m.
When did momondo last update prices for flights from Des Moines Airport to Santa Fe Airport?
Prices for flights from Des Moines Airport to Santa Fe Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Santa Fe Airport?
The number of operators available for flights from Des Moines Airport to Santa Fe Airport is 1 as of February 2026.
How old do you have to be to fly from Des Moines Airport to Santa Fe Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Fe Airport.
What documentation or ID do you need to fly to Santa Fe Airport?
The necessary travel and health documents for your Santa Fe Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Santa Fe?
momondo data reveals that the most frequently booked airline on the route from Des Moines to Santa Fe is United Airlines, representing 100% of all bookings.

Best airlines flying from Des Moines to Santa Fe

Compare and see reviews for airlines that fly from Des Moines to Santa Fe with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $249	Free Cancellation	Rating 7.4 9,236 reviews		Search United Airlines flights

Santa Rosa

Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santa Fe?

It is quick and easy to find Des Moines to Santa Fe flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Fe that suits you.

Can I find flights from Des Moines to Santa Fe with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Santa Fe flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Santa Fe?

momondo provides multiple filters to help you find the best flight to Santa Fe from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Santa Fe right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Fe from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.