What airlines fly to Santa Fe?

United Airlines, American Airlines and Southwest are the top three most popular airlines that fly to Santa Fe from Des Moines according to our data. United Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Santa Fe. Keep in mind that there are 3 different airlines that fly to Santa Fe on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Santa Fe Airport?

Prices for flights from Des Moines Airport to Santa Fe Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Santa Fe Airport?

The number of operators available for flights from Des Moines Airport to Santa Fe Airport is 1 as of September 2025.

How old do you have to be to fly from Des Moines Airport to Santa Fe Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Fe Airport.

What documentation or ID do you need to fly to Santa Fe Airport?

The necessary travel and health documents for your Santa Fe Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$240 Cheap Flights from Des Moines to Santa Fe in 2025/26

Q: What is the typical price of a round-trip flight between Des Moines and Santa Fe?

Prices are currently low for flights on this route. Typical prices usually range from $318 to $400. The lowest price recently found on this route was $244.

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Find the cheapest flights from Des Moines to Santa Fe

Round-trip

One-way

Cheap round-trip flights

3:48 pm - 9:01 pmDSM-SAF

6h 13m1 stop

5:07 pm - 11:16 pmSAF-DSM

5h 09m1 stop

$244American Airlines

Find Deal

Sat, Oct 18 - Tue, Oct 28

6:00 am - 9:24 amDSM-SAF

4h 24m1 stop

5:59 pm - 11:56 pmSAF-DSM

4h 57m1 stop

$254United Airlines

Find Deal

Tue, Oct 7 - Sat, Oct 11

6:00 am - 9:24 amDSM-SAF

4h 24m1 stop

10:45 am - 4:17 pmSAF-DSM

4h 32m1 stop

$294United Airlines

Find Deal

Sat, Oct 4 - Wed, Oct 15

5:00 am - 9:50 amDSM-SAF

5h 50m1 stop

5:07 pm - 11:16 pmSAF-DSM

5h 09m1 stop

$340American Airlines

Find Deal

Wed, Oct 15 - Wed, Oct 22

6:00 am - 9:24 amDSM-SAF

4h 24m1 stop

6:00 pm - 11:44 pmSAF-DSM

4h 44m1 stop

$405United Airlines

Find Deal

Mon, Oct 20 - Mon, Oct 27

5:45 am - 9:25 amDSM-SAF

4h 40m1 stop

6:00 pm - 11:42 pmSAF-DSM

4h 42m1 stop

$410United Airlines

Find Deal

Fri, Nov 7 - Fri, Nov 14

5:30 am - 4:06 pmDSM-SAF

11h 36m2 stops

5:07 pm - 11:16 pmSAF-DSM

5h 09m1 stop

$433American Airlines

Find Deal

Sat, Oct 18 - Tue, Oct 28

5:04 am - 9:51 amDSM-SAF

5h 47m1 stop

5:07 pm - 10:56 pmSAF-DSM

4h 49m1 stop

$435American Airlines

Find Deal

Mon, Oct 20 - Mon, Oct 27

6:36 pm - 9:24 amDSM-SAF

15h 48m2 stops

1:23 pm - 8:18 pmSAF-DSM

5h 55m1 stop

$443United Airlines

Find Deal

Wed, Oct 15 - Wed, Oct 22

9:22 am - 3:42 pmDSM-SAF

7h 20m1 stop

4:51 pm - 10:40 pmSAF-DSM

4h 49m1 stop

$453American Airlines

Find Deal

Wed, Feb 4 - Sun, Feb 8

United Airlines flights from Des Moines to Santa Fe

Our best United Airlines deals on Des Moines to Santa Fe flight tickets

United Airlines

Oct 7

DSM6:00 amDes Moines

4h 24m

1 stop

SAF9:24 amSanta Fe

Oct 11

SAF5:59 pmSanta Fe

4h 57m

1 stop

DSM11:56 pmDes Moines

$254

Find similar

United Airlines

Oct 4

DSM6:00 amDes Moines

4h 24m

1 stop

SAF9:24 amSanta Fe

Oct 15

SAF10:45 amSanta Fe

4h 32m

1 stop

DSM4:17 pmDes Moines

$294

Find similar

United Airlines

Oct 20

DSM6:00 amDes Moines

4h 24m

1 stop

SAF9:24 amSanta Fe

Oct 27

SAF6:00 pmSanta Fe

4h 44m

1 stop

DSM11:44 pmDes Moines

$405

Find similar

American Airlines flights from Des Moines to Santa Fe

Our best American Airlines deals on Des Moines to Santa Fe flight tickets

American Airlines

Oct 18

DSM3:48 pmDes Moines

6h 13m

1 stop

SAF9:01 pmSanta Fe

Oct 28

SAF5:07 pmSanta Fe

5h 09m

1 stop

DSM11:16 pmDes Moines

$244

Find similar

American Airlines

Oct 15

DSM5:00 amDes Moines

5h 50m

1 stop

SAF9:50 amSanta Fe

Oct 22

SAF5:07 pmSanta Fe

5h 09m

1 stop

DSM11:16 pmDes Moines

$340

Find similar

American Airlines

Oct 18

DSM5:30 amDes Moines

11h 36m

2 stops

SAF4:06 pmSanta Fe

Oct 28

SAF5:07 pmSanta Fe

5h 09m

1 stop

DSM11:16 pmDes Moines

$433

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 10/18

3:48 pm-9:01 pm

1 stop6h 13m

Santa Fe

Tue 10/28

5:07 pm-11:16 pm

1 stop5h 09m

$244

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Tue 10/7

6:00 am-9:24 am

1 stop4h 24m

Santa Fe

Sat 10/11

5:59 pm-11:56 pm

1 stop4h 57m

$254

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 10/4

6:00 am-9:24 am

1 stop4h 24m

Santa Fe

Wed 10/15

10:45 am-4:17 pm

1 stop4h 32m

$294

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Wed 10/15

5:00 am-9:50 am

1 stop5h 50m

Santa Fe

Wed 10/22

5:07 pm-11:16 pm

1 stop5h 09m

$340

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Mon 10/20

6:00 am-9:24 am

1 stop4h 24m

Santa Fe

Mon 10/27

6:00 pm-11:44 pm

1 stop4h 44m

$405

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Fri 11/7

5:45 am-9:25 am

1 stop4h 40m

Santa Fe

Fri 11/14

6:00 pm-11:42 pm

1 stop4h 42m

$410

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Sat 10/18

5:30 am-4:06 pm

2 stops11h 36m

Santa Fe

Tue 10/28

5:07 pm-11:16 pm

1 stop5h 09m

$433

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Mon 10/20

5:04 am-9:51 am

1 stop5h 47m

Santa Fe

Mon 10/27

5:07 pm-10:56 pm

1 stop4h 49m

$435

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Wed 10/15

6:36 pm-9:24 am

2 stops15h 48m

Santa Fe

Wed 10/22

1:23 pm-8:18 pm

1 stop5h 55m

$443

Des MoinesSanta Fe

DSM - SAF

DSMSAF

Des Moines

Wed 2/4

9:22 am-3:42 pm

1 stop7h 20m

Santa Fe

Sun 2/8

4:51 pm-10:40 pm

1 stop4h 49m

$453

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Des Moines and Santa Fe?

What is the cheapest day to depart on your flight to Santa Fe?

According to our data, Friday is the cheapest day to fly to Santa Fe from Des Moines. The lowest ticket price found for a Friday departure recently was $301. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santa Fe on Thursday is $510.

What is the cheapest time of day to depart on your flight to Santa Fe?

The cheapest time of day to fly to Santa Fe is at noon when flights can be purchased for as low as $333. Try not to purchase tickets in the morning because they tend to be around $440. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Des Moines to Santa Fe

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santa Fe according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Santa Fe (DSM to SAF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santa Fe

Direct flights	None

There are no direct flights from Des Moines to Santa Fe. There are no popular flight routes from Des Moines to Santa Fe.

Search flight deals

How far is Des Moines to Santa Fe by plane?
There are 777.7 mi between Des Moines and Santa Fe. A reasonable flight in good conditions will take 4h 24m.
When did momondo last update prices for flights from Des Moines Airport to Santa Fe Airport?
Prices for flights from Des Moines Airport to Santa Fe Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Santa Fe Airport?
The number of operators available for flights from Des Moines Airport to Santa Fe Airport is 1 as of September 2025.
How old do you have to be to fly from Des Moines Airport to Santa Fe Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Fe Airport.
What documentation or ID do you need to fly to Santa Fe Airport?
The necessary travel and health documents for your Santa Fe Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Santa Fe?
momondo data reveals that the most frequently booked airline on the route from Des Moines to Santa Fe is United Airlines, representing 100% of all bookings.

Best airlines flying from Des Moines to Santa Fe

Compare and see reviews for airlines that fly from Des Moines to Santa Fe with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $278	Free Cancellation	Rating 7.4 8,928 reviews		Search United Airlines flights

Santa Rosa

Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santa Fe?

It is quick and easy to find Des Moines to Santa Fe flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Fe that suits you.

Can I find flights from Des Moines to Santa Fe with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Santa Fe flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Santa Fe?

momondo provides multiple filters to help you find the best flight to Santa Fe from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Santa Fe right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Fe from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.