What is the cheapest airline that flies from Des Moines to Mississippi?

American Airlines, Southwest, and United Airlines are the most popular carriers operating from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?

Prices for flights from Des Moines Airport to Mississippi refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Mississippi?

There are 3 operators available for flights from Des Moines Airport to Mississippi as of July 2026.

How old do you have to be to fly from Des Moines Airport to Mississippi?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$140 Cheap Flights from Des Moines to Mississippi in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:31 am - 5:04 pm

DSM

MEM

5h 33m

1 stop

6:00 am - 10:17 am

MEM

DSM

4h 17m

1 stop

$279Delta

Thu, Sep 10 - Thu, Sep 17

7:58 pm - 12:22 am

DSM

MEM

4h 24m

1 stop

5:40 pm - 11:12 pm

MEM

DSM

5h 32m

1 stop

$279American Airlines

Thu, Sep 17 - Sat, Sep 19

3:50 pm - 10:30 pm

DSM

MEM

6h 40m

1 stop

5:15 am - 11:25 am

MEM

DSM

6h 10m

1 stop

$304Southwest

Mon, Sep 14 - Fri, Sep 18

5:40 am - 11:40 am

DSM

MEM

6h 00m

1 stop

3:20 pm - 10:10 pm

MEM

DSM

6h 50m

1 stop

$304Southwest

Fri, Aug 28 - Mon, Aug 31

7:58 pm - 12:22 am

DSM

MEM

4h 24m

1 stop

5:34 pm - 12:04 am

MEM

DSM

6h 30m

1 stop

$304American Airlines

Mon, Sep 14 - Fri, Sep 18

5:59 pm - 10:22 pm

DSM

MEM

4h 23m

1 stop

3:30 pm - 10:26 pm

MEM

DSM

6h 56m

1 stop

$304Delta

Mon, Sep 21 - Fri, Sep 25

6:22 pm - 10:50 pm

DSM

MEM

4h 28m

1 stop

5:20 pm - 11:07 pm

MEM

DSM

5h 47m

1 stop

$306American Airlines

Fri, Sep 4 - Sun, Sep 6

11:31 am - 4:18 pm

DSM

JAN

4h 47m

1 stop

8:00 am - 3:15 pm

JAN

DSM

7h 15m

1 stop

$309Delta

Sat, Sep 12 - Sat, Sep 19

6:15 am - 11:13 am

DSM

BTR

4h 58m

1 stop

7:15 am - 4:19 pm

BTR

DSM

9h 04m

2 stops

$324United Airlines

Tue, Aug 18 - Tue, Aug 25

5:45 am - 1:16 pm

DSM

BTR

7h 31m

2 stops

7:15 am - 4:19 pm

BTR

DSM

9h 04m

2 stops

$329United Airlines

Tue, Aug 18 - Tue, Aug 25

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Delta flights from Des Moines to Mississippi

Our best Delta deals on Des Moines to Mississippi flight tickets

Delta

Sep 10

DSM11:31 amDes Moines

5h 33m

1 stop

MEM5:04 pmMemphis

Sep 17

MEM6:00 amMemphis

4h 17m

1 stop

DSM10:17 amDes Moines

$279

Delta

Sep 12

DSM11:31 amDes Moines

4h 47m

1 stop

JAN4:18 pmJackson-Evers Intl

Sep 19

JAN8:00 amJackson-Evers Intl

7h 15m

1 stop

DSM3:15 pmDes Moines

$309

Delta

Sep 14

DSM6:54 pmDes Moines

4h 26m

1 stop

MOB11:20 pmMobile

Sep 25

MOB6:10 pmMobile

4h 16m

1 stop

DSM10:26 pmDes Moines

$319

Southwest flights from Des Moines to Mississippi

Our best Southwest deals on Des Moines to Mississippi flight tickets

Southwest

Sep 14

DSM3:50 pmDes Moines

6h 40m

1 stop

MEM10:30 pmMemphis

Sep 18

MEM5:15 amMemphis

6h 10m

1 stop

DSM11:25 amDes Moines

$304

Southwest

Sep 14

DSM3:50 pmDes Moines

6h 40m

1 stop

MEM10:30 pmMemphis

Sep 18

MEM2:55 pmMemphis

7h 20m

2 stops

DSM10:15 pmDes Moines

$309

Southwest

Sep 11

DSM2:25 pmDes Moines

7h 10m

1 stop

MEM9:35 pmMemphis

Sep 18

MEM11:20 amMemphis

10h 55m

2 stops

DSM10:15 pmDes Moines

$311

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 9/10

11:31 am-5:04 pm

1 stop5h 33m

Memphis

Thu 9/17

6:00 am-10:17 am

1 stop4h 17m

$279

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 9/17

7:58 pm-12:22 am

1 stop4h 24m

Memphis

Sat 9/19

5:40 pm-11:12 pm

1 stop5h 32m

$279

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 9/14

3:50 pm-10:30 pm

1 stop6h 40m

Memphis

Fri 9/18

5:15 am-11:25 am

1 stop6h 10m

$304

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 8/28

5:40 am-11:40 am

1 stop6h 00m

Memphis

Mon 8/31

3:20 pm-10:10 pm

1 stop6h 50m

$304

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 9/14

7:58 pm-12:22 am

1 stop4h 24m

Memphis

Fri 9/18

5:34 pm-12:04 am

1 stop6h 30m

$304

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 9/21

5:59 pm-10:22 pm

1 stop4h 23m

Memphis

Fri 9/25

3:30 pm-10:26 pm

1 stop6h 56m

$304

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 9/4

6:22 pm-10:50 pm

1 stop4h 28m

Memphis

Sun 9/6

5:20 pm-11:07 pm

1 stop5h 47m

$306

Des MoinesJackson

DSM - JAN

DSMJAN

Des Moines

Sat 9/12

11:31 am-4:18 pm

1 stop4h 47m

Jackson-Evers Intl

Sat 9/19

8:00 am-3:15 pm

1 stop7h 15m

$309

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 8/18

6:15 am-11:13 am

1 stop4h 58m

Baton Rouge Ryan

Tue 8/25

7:15 am-4:19 pm

2 stops9h 04m

$324

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 8/18

5:45 am-1:16 pm

2 stops7h 31m

Baton Rouge Ryan

Tue 8/25

7:15 am-4:19 pm

2 stops9h 04m

$329

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Mississippi?

The month of June is, on average, the cheapest month to fly to Mississippi from Des Moines, with most prices found around $0. If you don’t want to visit Mississippi in June, then you should wait until April to fly from Des Moines, when ticket prices are also cheap, with an average price of $0.

Can stopping save me money on Des Moines to Mississippi flights?

You could potentially save up to 44% on your flight if you consider stops on a Des Moines to Mississippi flight.

Cheap Des Moines to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mississippi

Fastest flight time	4h 15m
Direct flights	None

The fastest flight from Des Moines to Mississippi takes 4h 15m

There are no direct flights from Des Moines to Mississippi. There are no popular flight routes from Des Moines to Mississippi.

Search flight deals

Frequently asked questions about flying from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?
Prices for flights from Des Moines Airport to Mississippi refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Mississippi?
There are 3 operators available for flights from Des Moines Airport to Mississippi as of July 2026.
How old do you have to be to fly from Des Moines Airport to Mississippi?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mississippi

Compare and see reviews for airlines that fly from Des Moines to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,839 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mississippi?

Finding the right flight to Mississippi from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mississippi quick and easy, saving you time and money.

Can I find flights from Des Moines to Mississippi with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Mississippi flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Mississippi?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mississippi from Des Moines.

I’m not ready to book a flight from Des Moines to Mississippi right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Mississippi now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mississippi and let you know when they change.