What is the cheapest airline that flies from Des Moines to Mississippi?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?

Prices for flights from Des Moines Airport to Mississippi refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Mississippi?

There are 3 operators available for flights from Des Moines Airport to Mississippi as of April 2026.

How old do you have to be to fly from Des Moines Airport to Mississippi?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$136 Cheap Flights from Des Moines to Mississippi in 2026

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Find the cheapest flights from Des Moines to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:01 pm - 11:59 pm

DSM

MEM

6h 58m

1 stop

7:34 pm - 11:49 pm

MEM

DSM

4h 15m

1 stop

$285American Airlines

Mon, May 4 - Mon, May 11

4:20 pm - 11:25 pm

DSM

MEM

7h 05m

1 stop

4:25 pm - 11:05 pm

MEM

DSM

6h 40m

2 stops

$290Southwest

Mon, May 11 - Mon, May 18

11:04 am - 6:16 pm

DSM

MOB

7h 12m

1 stop

12:10 pm - 5:42 pm

MOB

DSM

5h 32m

1 stop

$311Delta

Wed, Sep 23 - Tue, Sep 29

3:20 pm - 10:51 pm

DSM

GPT

7h 31m

1 stop

5:00 am - 11:26 am

GPT

DSM

6h 26m

1 stop

$311American Airlines

Sat, May 2 - Tue, May 12

4:13 pm - 11:03 pm

DSM

MOB

6h 50m

1 stop

12:41 pm - 10:27 pm

MOB

DSM

9h 46m

2 stops

$316American Airlines

Sat, Sep 26 - Wed, Sep 30

2:16 pm - 11:58 pm

DSM

GPT

9h 42m

2 stops

5:00 am - 11:26 am

GPT

DSM

6h 26m

1 stop

$316American Airlines

Sat, May 2 - Tue, May 12

6:30 pm - 10:55 pm

DSM

MOB

4h 25m

1 stop

4:15 pm - 10:26 pm

MOB

DSM

6h 11m

1 stop

$320Delta

Fri, Sep 25 - Tue, Sep 29

4:20 pm - 11:25 pm

DSM

MEM

7h 05m

1 stop

4:25 pm - 11:05 pm

MEM

DSM

6h 40m

2 stops

$325Southwest

Mon, May 4 - Mon, May 11

9:00 am - 9:59 pm

DSM

MOB

12h 59m

2 stops

9:00 am - 2:22 pm

MOB

DSM

5h 22m

1 stop

$344United Airlines

Tue, Apr 14 - Sat, Apr 18

6:20 am - 4:20 pm

DSM

MOB

10h 00m

2 stops

7:00 am - 4:15 pm

MOB

DSM

9h 15m

2 stops

$349United Airlines

Tue, Apr 14 - Sat, Apr 18

Southwest flights from Des Moines to Mississippi

Our best Southwest deals on Des Moines to Mississippi flight tickets

Southwest

May 11

DSM4:20 pmDes Moines

7h 05m

1 stop

MEM11:25 pmMemphis

May 18

MEM4:25 pmMemphis

6h 40m

2 stops

DSM11:05 pmDes Moines

$290

Southwest

May 4

DSM4:20 pmDes Moines

7h 05m

1 stop

MEM11:25 pmMemphis

May 11

MEM4:25 pmMemphis

6h 40m

2 stops

DSM11:05 pmDes Moines

$325

Southwest

May 16

DSM5:35 amDes Moines

6h 05m

1 stop

MEM11:40 amMemphis

May 23

MEM5:25 amMemphis

7h 55m

2 stops

DSM1:20 pmDes Moines

$344

United Airlines flights from Des Moines to Mississippi

Our best United Airlines deals on Des Moines to Mississippi flight tickets

United Airlines

Apr 14

DSM3:04 pmDes Moines

6h 55m

1 stop

MOB9:59 pmMobile

Apr 18

MOB9:00 amMobile

5h 22m

1 stop

DSM2:22 pmDes Moines

$339

United Airlines

Apr 14

DSM9:00 amDes Moines

12h 59m

2 stops

MOB9:59 pmMobile

Apr 18

MOB9:00 amMobile

5h 22m

1 stop

DSM2:22 pmDes Moines

$344

United Airlines

Apr 14

DSM6:20 amDes Moines

10h 00m

2 stops

MOB4:20 pmMobile

Apr 18

MOB7:00 amMobile

9h 15m

2 stops

DSM4:15 pmDes Moines

$349

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 5/4

5:01 pm-11:59 pm

1 stop6h 58m

Memphis

Mon 5/11

7:34 pm-11:49 pm

1 stop4h 15m

$285

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 5/11

4:20 pm-11:25 pm

1 stop7h 05m

Memphis

Mon 5/18

4:25 pm-11:05 pm

2 stops6h 40m

$290

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 9/23

11:04 am-6:16 pm

1 stop7h 12m

Mobile

Tue 9/29

12:10 pm-5:42 pm

1 stop5h 32m

$311

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Sat 5/2

3:20 pm-10:51 pm

1 stop7h 31m

Gulfport Biloxi Regional

Tue 5/12

5:00 am-11:26 am

1 stop6h 26m

$311

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 9/26

4:13 pm-11:03 pm

1 stop6h 50m

Mobile

Wed 9/30

12:41 pm-10:27 pm

2 stops9h 46m

$316

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Sat 5/2

2:16 pm-11:58 pm

2 stops9h 42m

Gulfport Biloxi Regional

Tue 5/12

5:00 am-11:26 am

1 stop6h 26m

$316

Quickest round-trip

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Fri 9/25

6:30 pm-10:55 pm

1 stop4h 25m

Mobile

Tue 9/29

4:15 pm-10:26 pm

1 stop6h 11m

$320

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 5/4

4:20 pm-11:25 pm

1 stop7h 05m

Memphis

Mon 5/11

4:25 pm-11:05 pm

2 stops6h 40m

$325

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 4/14

9:00 am-9:59 pm

2 stops12h 59m

Mobile

Sat 4/18

9:00 am-2:22 pm

1 stop5h 22m

$344

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 4/14

6:20 am-4:20 pm

2 stops10h 00m

Mobile

Sat 4/18

7:00 am-4:15 pm

2 stops9h 15m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Des Moines to Mississippi flights?

You could potentially save up to 28% on your flight if you consider stops on a Des Moines to Mississippi flight.

Cheap Des Moines to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mississippi

Fastest flight time	4h 25m
Direct flights	None

The fastest flight from Des Moines to Mississippi takes 4h 25m

There are no direct flights from Des Moines to Mississippi. There are no popular flight routes from Des Moines to Mississippi.

Search flight deals

Frequently asked questions about flying from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?
Prices for flights from Des Moines Airport to Mississippi refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Mississippi?
There are 3 operators available for flights from Des Moines Airport to Mississippi as of April 2026.
How old do you have to be to fly from Des Moines Airport to Mississippi?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mississippi

Compare and see reviews for airlines that fly from Des Moines to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,550 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mississippi?

Finding the right flight to Mississippi from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mississippi quick and easy, saving you time and money.

Can I find flights from Des Moines to Mississippi with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Mississippi flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Mississippi?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mississippi from Des Moines.

I’m not ready to book a flight from Des Moines to Mississippi right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Mississippi now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mississippi and let you know when they change.