What is the cheapest airline that flies from Des Moines to Mississippi?

American Airlines and Delta are the most popular carriers operating from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?

Prices for flights from Des Moines Airport to Mississippi refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Mississippi?

There is 1 operator available for flights from Des Moines Airport to Mississippi as of September 2026.

How old do you have to be to fly from Des Moines Airport to Mississippi?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$217 Cheap Flights from Des Moines to Mississippi in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:54 pm - 11:09 pmDSM Des Moines-JAN Jackson-Evers Intl

4h 15m1 stop Atlanta Hartsfield-Jackson

3:33 pm - 10:33 pmJAN Jackson-Evers Intl-DSM Des Moines

7h 00m1 stop Atlanta Hartsfield-Jackson

$329Delta

Tue, Oct 20 - Mon, Oct 26

6:00 am - 11:27 amDSM Des Moines-JAN Jackson-Evers Intl

5h 27m1 stop Houston George Bush Intcntl

5:23 pm - 10:30 pmJAN Jackson-Evers Intl-DSM Des Moines

5h 07m1 stop Houston George Bush Intcntl

$329United Airlines

Thu, Oct 22 - Tue, Oct 27

6:00 am - 11:27 amDSM Des Moines-JAN Jackson-Evers Intl

5h 27m1 stop Houston George Bush Intcntl

11:57 am - 10:59 pmJAN Jackson-Evers Intl-DSM Des Moines

11h 02m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$334United Airlines

Thu, Oct 22 - Tue, Oct 27

2:58 pm - 9:57 pmDSM Des Moines-GPT Gulfport Biloxi Regional

6h 59m1 stop Atlanta Hartsfield-Jackson

6:09 pm - 10:38 pmGPT Gulfport Biloxi Regional-DSM Des Moines

4h 29m1 stop Atlanta Hartsfield-Jackson

$339Delta

Fri, Dec 11 - Mon, Dec 14

2:58 pm - 9:57 pmDSM Des Moines-GPT Gulfport Biloxi Regional

6h 59m1 stop Atlanta Hartsfield-Jackson

6:15 am - 10:49 amGPT Gulfport Biloxi Regional-DSM Des Moines

4h 34m1 stop Atlanta Hartsfield-Jackson

$339Delta

Fri, Dec 11 - Sun, Dec 13

4:07 pm - 9:37 pmDSM Des Moines-JAN Jackson-Evers Intl

5h 30m1 stop Atlanta Hartsfield-Jackson

9:18 am - 2:09 pmJAN Jackson-Evers Intl-DSM Des Moines

4h 51m1 stop Atlanta Hartsfield-Jackson

$353Delta

Wed, Nov 4 - Sun, Nov 8

5:35 am - 1:01 pmDSM Des Moines-GPT Gulfport Biloxi Regional

7h 26m1 stop Atlanta Hartsfield-Jackson

10:03 am - 3:16 pmGPT Gulfport Biloxi Regional-DSM Des Moines

5h 13m1 stop Atlanta Hartsfield-Jackson

$369Delta

Tue, Oct 6 - Sat, Oct 10

11:27 am - 7:38 pmDSM Des Moines-GPT Gulfport Biloxi Regional

8h 11m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

5:14 pm - 10:16 pmGPT Gulfport Biloxi Regional-DSM Des Moines

5h 02m1 stop Houston George Bush Intcntl

$374United Airlines

Tue, Oct 6 - Sat, Oct 10

6:14 pm - 11:37 pmDSM Des Moines-GPT Gulfport Biloxi Regional

5h 23m1 stop Dallas/Fort Worth

5:39 pm - 11:41 pmGPT Gulfport Biloxi Regional-DSM Des Moines

6h 02m1 stop Charlotte Douglas

$452American Airlines

Fri, Feb 5 - Mon, Feb 8

4:12 pm - 10:59 pmDSM Des Moines-JAN Jackson-Evers Intl

6h 47m1 stop Dallas/Fort Worth

6:45 pm - 11:58 pmJAN Jackson-Evers Intl-DSM Des Moines

5h 13m1 stop Charlotte Douglas

$504American Airlines

Thu, Oct 15 - Wed, Oct 21

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Delta flights from Des Moines to Mississippi

Our best Delta deals on Des Moines to Mississippi flight tickets

Delta

Oct 20

DSM6:54 pmDes Moines

4h 15m

1 stop

JAN11:09 pmJackson-Evers Intl

Oct 26

JAN3:33 pmJackson-Evers Intl

7h 00m

1 stop

DSM10:33 pmDes Moines

$329

Delta

Dec 11

DSM2:58 pmDes Moines

6h 59m

1 stop

GPT9:57 pmGulfport Biloxi Regional

Dec 13

GPT6:15 amGulfport Biloxi Regional

4h 34m

1 stop

DSM10:49 amDes Moines

$339

Delta

Nov 4

DSM4:07 pmDes Moines

5h 30m

1 stop

JAN9:37 pmJackson-Evers Intl

Nov 8

JAN9:18 amJackson-Evers Intl

4h 51m

1 stop

DSM2:09 pmDes Moines

$353

United Airlines flights from Des Moines to Mississippi

Our best United Airlines deals on Des Moines to Mississippi flight tickets

United Airlines

Oct 22

DSM6:00 amDes Moines

5h 27m

1 stop

JAN11:27 amJackson-Evers Intl

Oct 27

JAN11:57 amJackson-Evers Intl

11h 02m

2 stops

DSM10:59 pmDes Moines

$334

United Airlines

Oct 6

DSM11:27 amDes Moines

8h 11m

2 stops

GPT7:38 pmGulfport Biloxi Regional

Oct 10

GPT5:14 pmGulfport Biloxi Regional

5h 02m

1 stop

DSM10:16 pmDes Moines

$374

United Airlines

Oct 6

DSM8:00 amDes Moines

8h 12m

2 stops

GPT4:12 pmGulfport Biloxi Regional

Oct 10

GPT2:00 pmGulfport Biloxi Regional

9h 35m

2 stops

DSM11:35 pmDes Moines

$379

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesJackson

DSM Des Moines - JAN Jackson-Evers Intl

DSMJAN

Des Moines

Tue 10/20

6:54 pm-11:09 pm

1 stop4h 15m

Jackson-Evers Intl

Mon 10/26

3:33 pm-10:33 pm

1 stop7h 00m

$329

Des MoinesJackson

DSM Des Moines - JAN Jackson-Evers Intl

DSMJAN

Des Moines

Thu 10/22

6:00 am-11:27 am

1 stop5h 27m

Jackson-Evers Intl

Tue 10/27

5:23 pm-10:30 pm

1 stop5h 07m

$329

Des MoinesJackson

DSM Des Moines - JAN Jackson-Evers Intl

DSMJAN

Des Moines

Thu 10/22

6:00 am-11:27 am

1 stop5h 27m

Jackson-Evers Intl

Tue 10/27

11:57 am-10:59 pm

2 stops11h 02m

$334

Des MoinesGulfport

DSM Des Moines - GPT Gulfport Biloxi Regional

DSMGPT

Des Moines

Fri 12/11

2:58 pm-9:57 pm

1 stop6h 59m

Gulfport Biloxi Regional

Mon 12/14

6:09 pm-10:38 pm

1 stop4h 29m

$339

Des MoinesGulfport

DSM Des Moines - GPT Gulfport Biloxi Regional

DSMGPT

Des Moines

Fri 12/11

2:58 pm-9:57 pm

1 stop6h 59m

Gulfport Biloxi Regional

Sun 12/13

6:15 am-10:49 am

1 stop4h 34m

$339

Quickest round-trip

Des MoinesJackson

DSM Des Moines - JAN Jackson-Evers Intl

DSMJAN

Des Moines

Wed 11/4

4:07 pm-9:37 pm

1 stop5h 30m

Jackson-Evers Intl

Sun 11/8

9:18 am-2:09 pm

1 stop4h 51m

$353

Des MoinesGulfport

DSM Des Moines - GPT Gulfport Biloxi Regional

DSMGPT

Des Moines

Tue 10/6

5:35 am-1:01 pm

1 stop7h 26m

Gulfport Biloxi Regional

Sat 10/10

10:03 am-3:16 pm

1 stop5h 13m

$369

Des MoinesGulfport

DSM Des Moines - GPT Gulfport Biloxi Regional

DSMGPT

Des Moines

Tue 10/6

11:27 am-7:38 pm

2 stops8h 11m

Gulfport Biloxi Regional

Sat 10/10

5:14 pm-10:16 pm

1 stop5h 02m

$374

Des MoinesGulfport

DSM Des Moines - GPT Gulfport Biloxi Regional

DSMGPT

Des Moines

Fri 2/5

6:14 pm-11:37 pm

1 stop5h 23m

Gulfport Biloxi Regional

Mon 2/8

5:39 pm-11:41 pm

1 stop6h 02m

$452

Des MoinesJackson

DSM Des Moines - JAN Jackson-Evers Intl

DSMJAN

Des Moines

Thu 10/15

4:12 pm-10:59 pm

1 stop6h 47m

Jackson-Evers Intl

Wed 10/21

6:45 pm-11:58 pm

1 stop5h 13m

$504

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Des Moines to Mississippi flights?

You could potentially save up to 44% on your flight if you consider stops on a Des Moines to Mississippi flight.

Cheap Des Moines to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mississippi

Best Price Found	$217
Fastest flight time	4h 26m
Direct flights	None

The best one-way flight to Mississippi from Des Moines in the past 72 hours is $217. The best round-trip flight deal from Des Moines to Mississippi found on momondo in the last 72 hours is $329.

The fastest flight from Des Moines to Mississippi takes 4h 26m

There are no direct flights from Des Moines to Mississippi. There are no popular flight routes from Des Moines to Mississippi.

Search flight deals

Frequently asked questions about flying from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?
Prices for flights from Des Moines Airport to Mississippi refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Mississippi?
There is 1 operator available for flights from Des Moines Airport to Mississippi as of September 2026.
How old do you have to be to fly from Des Moines Airport to Mississippi?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mississippi

Compare and see reviews for airlines that fly from Des Moines to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $366	Free Cancellation	Rating 7.0 12,076 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mississippi?

Finding the right flight to Mississippi from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mississippi quick and easy, saving you time and money.

Can I find flights from Des Moines to Mississippi with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Mississippi flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Mississippi?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mississippi from Des Moines.

I’m not ready to book a flight from Des Moines to Mississippi right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Mississippi now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mississippi and let you know when they change.