What is the cheapest airline that flies from Des Moines to Mississippi?

Southwest, United Airlines, and Delta are the most popular carriers operating from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?

Prices for flights from Des Moines Airport to Mississippi refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Mississippi?

There are 3 operators available for flights from Des Moines Airport to Mississippi as of May 2026.

How old do you have to be to fly from Des Moines Airport to Mississippi?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$141 Cheap Flights from Des Moines to Mississippi in 2026

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Find the cheapest flights from Des Moines to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:48 pm - 10:24 pm

DSM

MEM

5h 36m

1 stop

6:10 am - 1:21 pm

MEM

DSM

7h 11m

1 stop

$281American Airlines

Tue, Jun 23 - Tue, Jun 30

3:22 pm - 10:28 pm

DSM

MEM

7h 06m

1 stop

5:00 am - 1:21 pm

MEM

DSM

8h 21m

2 stops

$286American Airlines

Tue, Jun 23 - Tue, Jun 30

3:00 pm - 10:21 pm

DSM

GPT

7h 21m

1 stop

6:01 pm - 10:37 pm

GPT

DSM

4h 36m

1 stop

$309Delta

Sun, Aug 23 - Sun, Aug 30

1:41 pm - 9:30 pm

DSM

BTR

7h 49m

1 stop

6:16 pm - 11:58 pm

BTR

DSM

5h 42m

1 stop

$309American Airlines

Tue, Jul 7 - Mon, Aug 3

10:59 am - 6:00 pm

DSM

MEM

7h 01m

1 stop

5:00 pm - 10:37 pm

MEM

DSM

5h 37m

1 stop

$314Delta

Tue, Aug 18 - Fri, Aug 21

6:10 am - 5:15 pm

DSM

MEM

11h 05m

2 stops

5:15 am - 11:25 am

MEM

DSM

6h 10m

1 stop

$319Southwest

Tue, Aug 18 - Fri, Aug 21

2:40 pm - 9:45 pm

DSM

MEM

7h 05m

2 stops

2:55 pm - 10:10 pm

MEM

DSM

7h 15m

2 stops

$324Southwest

Tue, Aug 18 - Fri, Aug 21

3:02 pm - 9:56 pm

DSM

MEM

6h 54m

1 stop

6:15 am - 10:26 am

MEM

DSM

4h 11m

1 stop

$351United Airlines

Tue, Aug 18 - Wed, Aug 19

3:00 pm - 7:38 pm

DSM

AEX

4h 38m

1 stop

5:15 am - 4:14 pm

AEX

DSM

10h 59m

2 stops

$384United Airlines

Wed, Oct 28 - Sat, Oct 31

9:33 pm - 4:51 pm

DSM

GPT

19h 18m

1 stop

7:25 pm - 4:40 pm

GPT

DSM

21h 15m

2 stops

$491Multiple Airlines

Thu, Jul 16 - Sun, Jul 19

Southwest flights from Des Moines to Mississippi

Our best Southwest deals on Des Moines to Mississippi flight tickets

Southwest

Aug 18

DSM6:10 amDes Moines

11h 05m

2 stops

MEM5:15 pmMemphis

Aug 21

MEM5:15 amMemphis

6h 10m

1 stop

DSM11:25 amDes Moines

$319

Southwest

Aug 18

DSM2:40 pmDes Moines

7h 05m

2 stops

MEM9:45 pmMemphis

Aug 21

MEM2:55 pmMemphis

7h 15m

2 stops

DSM10:10 pmDes Moines

$324

Southwest

Jul 4

DSM5:10 amDes Moines

6h 50m

1 stop

MEM12:00 pmMemphis

Jul 11

MEM5:00 amMemphis

6h 35m

1 stop

DSM11:35 amDes Moines

$347

American Airlines flights from Des Moines to Mississippi

Our best American Airlines deals on Des Moines to Mississippi flight tickets

American Airlines

Jun 23

DSM4:48 pmDes Moines

5h 36m

1 stop

MEM10:24 pmMemphis

Jun 30

MEM6:10 amMemphis

7h 11m

1 stop

DSM1:21 pmDes Moines

$281

American Airlines

Jun 23

DSM3:22 pmDes Moines

7h 06m

1 stop

MEM10:28 pmMemphis

Jun 30

MEM5:00 amMemphis

8h 21m

2 stops

DSM1:21 pmDes Moines

$286

American Airlines

Jul 7

DSM1:41 pmDes Moines

7h 49m

1 stop

BTR9:30 pmBaton Rouge Ryan

Aug 3

BTR6:16 pmBaton Rouge Ryan

5h 42m

1 stop

DSM11:58 pmDes Moines

$309

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 6/23

4:48 pm-10:24 pm

1 stop5h 36m

Memphis

Tue 6/30

6:10 am-1:21 pm

1 stop7h 11m

$281

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 6/23

3:22 pm-10:28 pm

1 stop7h 06m

Memphis

Tue 6/30

5:00 am-1:21 pm

2 stops8h 21m

$286

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Sun 8/23

3:00 pm-10:21 pm

1 stop7h 21m

Gulfport Biloxi Regional

Sun 8/30

6:01 pm-10:37 pm

1 stop4h 36m

$309

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 7/7

1:41 pm-9:30 pm

1 stop7h 49m

Baton Rouge Ryan

Mon 8/3

6:16 pm-11:58 pm

1 stop5h 42m

$309

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 8/18

10:59 am-6:00 pm

1 stop7h 01m

Memphis

Fri 8/21

5:00 pm-10:37 pm

1 stop5h 37m

$314

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 8/18

6:10 am-5:15 pm

2 stops11h 05m

Memphis

Fri 8/21

5:15 am-11:25 am

1 stop6h 10m

$319

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 8/18

2:40 pm-9:45 pm

2 stops7h 05m

Memphis

Fri 8/21

2:55 pm-10:10 pm

2 stops7h 15m

$324

Quickest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 8/18

3:02 pm-9:56 pm

1 stop6h 54m

Memphis

Wed 8/19

6:15 am-10:26 am

1 stop4h 11m

$351

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Wed 10/28

3:00 pm-7:38 pm

1 stop4h 38m

Alexandria

Sat 10/31

5:15 am-4:14 pm

2 stops10h 59m

$384

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Thu 7/16

9:33 pm-4:51 pm

1 stop19h 18m

Gulfport Biloxi Regional

Sun 7/19

7:25 pm-4:40 pm

2 stops21h 15m

$491

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Mississippi?

The month of April is, on average, the cheapest month to fly to Mississippi from Des Moines, with most prices found around $0. If you don’t want to visit Mississippi in April, then you should wait until December to fly from Des Moines, when ticket prices are also cheap, with an average price of $248.

Can stopping save me money on Des Moines to Mississippi flights?

You could potentially save up to 12% on your flight if you consider stops on a Des Moines to Mississippi flight.

Cheap Des Moines to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mississippi

Fastest flight time	4h 13m
Direct flights	None

The fastest flight from Des Moines to Mississippi takes 4h 13m

There are no direct flights from Des Moines to Mississippi. There are no popular flight routes from Des Moines to Mississippi.

Search flight deals

Frequently asked questions about flying from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?
Prices for flights from Des Moines Airport to Mississippi refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Mississippi?
There are 3 operators available for flights from Des Moines Airport to Mississippi as of May 2026.
How old do you have to be to fly from Des Moines Airport to Mississippi?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mississippi

Compare and see reviews for airlines that fly from Des Moines to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,631 reviews		Search American Airlines flights
United Airlines	PriceFrom $318	Free Cancellation	Rating 7.4 9,749 reviews		Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mississippi?

Finding the right flight to Mississippi from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mississippi quick and easy, saving you time and money.

Can I find flights from Des Moines to Mississippi with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Mississippi flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Mississippi?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mississippi from Des Moines.

I’m not ready to book a flight from Des Moines to Mississippi right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Mississippi now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mississippi and let you know when they change.