What is the cheapest airline that flies from Des Moines to Mississippi?

United Airlines, Southwest, and American Airlines are the most popular carriers operating from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?

Prices for flights from Des Moines Airport to Mississippi refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Mississippi?

There are 3 operators available for flights from Des Moines Airport to Mississippi as of February 2026.

How old do you have to be to fly from Des Moines Airport to Mississippi?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$126 Cheap Flights from Des Moines to Mississippi in 2026

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Find the cheapest flights from Des Moines to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:40 pm - 10:25 pm

DSM

MEM

6h 45m

1 stop

3:25 pm - 10:05 pm

MEM

DSM

6h 40m

1 stop

$251Southwest

Wed, Mar 25 - Tue, Mar 31

6:40 am - 1:55 pm

DSM

MEM

7h 15m

1 stop

1:10 pm - 10:05 pm

MEM

DSM

8h 55m

2 stops

$256Southwest

Wed, Mar 25 - Tue, Mar 31

6:55 am - 11:47 am

DSM

MEM

4h 52m

1 stop

5:37 pm - 10:38 pm

MEM

DSM

5h 01m

1 stop

$264Delta

Tue, Mar 24 - Mon, Mar 30

11:33 am - 6:07 pm

DSM

MOB

6h 34m

1 stop

9:13 am - 4:33 pm

MOB

DSM

7h 20m

1 stop

$269Delta

Wed, Apr 1 - Wed, Apr 8

5:05 am - 10:15 am

DSM

MOB

5h 10m

1 stop

10:49 am - 7:33 pm

MOB

DSM

8h 44m

2 stops

$274American Airlines

Wed, Apr 1 - Wed, Apr 8

2:00 pm - 7:26 pm

DSM

BTR

5h 26m

1 stop

5:00 am - 10:44 am

BTR

DSM

5h 44m

1 stop

$279American Airlines

Tue, Feb 24 - Sat, Feb 28

11:40 am - 9:59 pm

DSM

MOB

10h 19m

2 stops

9:00 am - 8:16 pm

MOB

DSM

11h 16m

2 stops

$279United Airlines

Tue, May 5 - Tue, May 12

8:20 am - 1:23 pm

DSM

JAN

5h 03m

1 stop

4:57 pm - 10:43 pm

JAN

DSM

5h 46m

1 stop

$332United Airlines

Wed, Apr 8 - Fri, Apr 10

7:45 am - 7:41 am

DSM

GPT

23h 56m

2 stops

7:50 pm - 9:33 am

GPT

DSM

13h 43m

1 stop

$466Multiple Airlines

Sun, May 10 - Sun, May 17

11:00 am - 4:51 pm

DSM

GPT

29h 51m

1 stop

7:50 pm - 9:33 am

GPT

DSM

13h 43m

1 stop

$506Multiple Airlines

Sun, May 10 - Sun, May 17

American Airlines flights from Des Moines to Mississippi

Our best American Airlines deals on Des Moines to Mississippi flight tickets

American Airlines

Apr 1

DSM5:05 amDes Moines

5h 10m

1 stop

MOB10:15 amMobile

Apr 8

MOB10:49 amMobile

8h 44m

2 stops

DSM7:33 pmDes Moines

$274

American Airlines

Mar 28

DSM1:37 pmDes Moines

5h 10m

1 stop

MEM6:47 pmMemphis

Apr 4

MEM6:11 pmMemphis

5h 35m

1 stop

DSM11:46 pmDes Moines

$278

American Airlines

Feb 24

DSM2:00 pmDes Moines

5h 26m

1 stop

BTR7:26 pmBaton Rouge Ryan

Feb 28

BTR5:00 amBaton Rouge Ryan

5h 44m

1 stop

DSM10:44 amDes Moines

$279

United Airlines flights from Des Moines to Mississippi

Our best United Airlines deals on Des Moines to Mississippi flight tickets

United Airlines

May 5

DSM11:40 amDes Moines

10h 19m

2 stops

MOB9:59 pmMobile

May 12

MOB9:00 amMobile

11h 16m

2 stops

DSM8:16 pmDes Moines

$279

United Airlines

Apr 8

DSM8:20 amDes Moines

5h 03m

1 stop

JAN1:23 pmJackson-Evers Intl

Apr 10

JAN4:57 pmJackson-Evers Intl

5h 46m

1 stop

DSM10:43 pmDes Moines

$332

United Airlines

Mar 24

DSM11:26 amDes Moines

10h 08m

2 stops

MEM9:34 pmMemphis

Mar 28

MEM7:30 amMemphis

14h 10m

1 stop

DSM9:40 pmDes Moines

$333

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 3/25

3:40 pm-10:25 pm

1 stop6h 45m

Memphis

Tue 3/31

3:25 pm-10:05 pm

1 stop6h 40m

$251

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 3/25

6:40 am-1:55 pm

1 stop7h 15m

Memphis

Tue 3/31

1:10 pm-10:05 pm

2 stops8h 55m

$256

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 3/24

6:55 am-11:47 am

1 stop4h 52m

Memphis

Mon 3/30

5:37 pm-10:38 pm

1 stop5h 01m

$264

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 4/1

11:33 am-6:07 pm

1 stop6h 34m

Mobile

Wed 4/8

9:13 am-4:33 pm

1 stop7h 20m

$269

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 4/1

5:05 am-10:15 am

1 stop5h 10m

Mobile

Wed 4/8

10:49 am-7:33 pm

2 stops8h 44m

$274

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 2/24

2:00 pm-7:26 pm

1 stop5h 26m

Baton Rouge Ryan

Sat 2/28

5:00 am-10:44 am

1 stop5h 44m

$279

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 5/5

11:40 am-9:59 pm

2 stops10h 19m

Mobile

Tue 5/12

9:00 am-8:16 pm

2 stops11h 16m

$279

Des MoinesJackson

DSM - JAN

DSMJAN

Des Moines

Wed 4/8

8:20 am-1:23 pm

1 stop5h 03m

Jackson-Evers Intl

Fri 4/10

4:57 pm-10:43 pm

1 stop5h 46m

$332

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Sun 5/10

7:45 am-7:41 am

2 stops23h 56m

Gulfport Biloxi Regional

Sun 5/17

7:50 pm-9:33 am

1 stop13h 43m

$466

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Sun 5/10

11:00 am-4:51 pm

1 stop29h 51m

Gulfport Biloxi Regional

Sun 5/17

7:50 pm-9:33 am

1 stop13h 43m

$506

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Des Moines to Mississippi flights?

You could potentially save up to 27% on your flight if you consider stops on a Des Moines to Mississippi flight.

Cheap Des Moines to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mississippi

Fastest flight time	4h 16m
Direct flights	None

The fastest flight from Des Moines to Mississippi takes 4h 16m

There are no direct flights from Des Moines to Mississippi. There are no popular flight routes from Des Moines to Mississippi.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Mississippi?
Prices for flights from Des Moines Airport to Mississippi refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Mississippi?
There are 3 operators available for flights from Des Moines Airport to Mississippi as of February 2026.
How old do you have to be to fly from Des Moines Airport to Mississippi?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mississippi

Compare and see reviews for airlines that fly from Des Moines to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,267 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mississippi?

Finding the right flight to Mississippi from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mississippi quick and easy, saving you time and money.

Can I find flights from Des Moines to Mississippi with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Mississippi flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Mississippi?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mississippi from Des Moines.

I’m not ready to book a flight from Des Moines to Mississippi right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Mississippi now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mississippi and let you know when they change.