What is the cheapest airline that flies from Des Moines to Mississippi?

Delta, American Airlines, and United Airlines are the most popular carriers operating from Des Moines to Mississippi

When did momondo last update prices for flights from Des Moines Airport to Mississippi?

Prices for flights from Des Moines Airport to Mississippi refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Mississippi?

There are 3 operators available for flights from Des Moines Airport to Mississippi as of December 2025.

How old do you have to be to fly from Des Moines Airport to Mississippi?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$240 Cheap Flights from Des Moines to Mississippi in 2025/26

1 adult

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Find the cheapest flights from Des Moines to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:24 am - 11:01 am

DSM

MEM

5h 37m1 stop

9:35 am - 4:27 pm

MEM

DSM

6h 52m1 stop

$240Delta

Sat, Feb 14 - Tue, Feb 17

10:09 am - 8:06 pm

DSM

MEM

9h 57m2 stops

6:00 am - 1:09 pm

MEM

DSM

7h 09m1 stop

$245American Airlines

Sat, Feb 14 - Tue, Feb 17

5:35 am - 11:55 am

DSM

MOB

6h 20m1 stop

6:00 am - 10:39 am

MOB

DSM

4h 39m1 stop

$249Delta

Wed, Apr 1 - Wed, Apr 8

5:16 pm - 10:01 pm

DSM

BTR

4h 45m1 stop

5:00 pm - 10:29 pm

BTR

DSM

5h 29m1 stop

$249Delta

Thu, Jan 22 - Tue, Jan 27

6:24 am - 4:19 pm

DSM

BTR

9h 55m2 stops

5:00 pm - 10:29 pm

BTR

DSM

5h 29m1 stop

$254Delta

Sat, Jan 24 - Tue, Jan 27

11:30 am - 9:32 pm

DSM

BTR

10h 02m2 stops

9:30 am - 8:34 pm

BTR

DSM

11h 04m2 stops

$309United Airlines

Sat, Jan 17 - Wed, Jan 21

8:30 am - 12:31 pm

DSM

MEM

28h 01m1 stop

8:18 pm - 10:19 am

MEM

DSM

14h 01m2 stops

$316Multiple Airlines

Sun, Jan 25 - Sun, Feb 1

8:10 am - 4:09 pm

DSM

MOB

7h 59m1 stop

4:50 pm - 10:30 pm

MOB

DSM

5h 40m1 stop

$319United Airlines

Sat, Jan 24 - Wed, Jan 28

2:58 pm - 10:49 am

DSM

MEM

19h 51m2 stops

8:18 pm - 10:19 am

MEM

DSM

14h 01m2 stops

$319Multiple Airlines

Sun, Jan 25 - Sun, Feb 1

8:35 am - 8:00 pm

DSM

JAN

11h 25m2 stops

11:50 am - 9:20 pm

JAN

DSM

9h 30m2 stops

$383Southwest

Thu, Jan 8 - Sun, Jan 11

Delta flights from Des Moines to Mississippi

Our best Delta deals on Des Moines to Mississippi flight tickets

Delta

Feb 14

DSM5:24 amDes Moines

5h 37m

1 stop

MEM11:01 amMemphis

Feb 17

MEM9:35 amMemphis

6h 52m

1 stop

DSM4:27 pmDes Moines

$240

Find similar

Delta

Apr 1

DSM5:35 amDes Moines

6h 20m

1 stop

MOB11:55 amMobile

Apr 8

MOB6:00 amMobile

4h 39m

1 stop

DSM10:39 amDes Moines

$249

Find similar

Delta

Jan 18

DSM6:54 amDes Moines

4h 49m

1 stop

MEM11:43 amMemphis

Jan 22

MEM10:32 amMemphis

6h 36m

1 stop

DSM5:08 pmDes Moines

$259

Find similar

American Airlines flights from Des Moines to Mississippi

Our best American Airlines deals on Des Moines to Mississippi flight tickets

American Airlines

Feb 14

DSM10:09 amDes Moines

9h 57m

2 stops

MEM8:06 pmMemphis

Feb 17

MEM6:00 amMemphis

7h 09m

1 stop

DSM1:09 pmDes Moines

$245

Find similar

American Airlines

Jan 18

DSM4:00 pmDes Moines

6h 51m

1 stop

MEM10:51 pmMemphis

Jan 22

MEM8:37 amMemphis

7h 47m

2 stops

DSM4:24 pmDes Moines

$264

Find similar

American Airlines

Apr 1

DSM7:45 amDes Moines

10h 35m

2 stops

MOB6:20 pmMobile

Apr 8

MOB6:00 pmMobile

4h 40m

1 stop

DSM10:40 pmDes Moines

$276

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 2/14

5:24 am-11:01 am

1 stop5h 37m

Memphis

Tue 2/17

9:35 am-4:27 pm

1 stop6h 52m

$240

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 2/14

10:09 am-8:06 pm

2 stops9h 57m

Memphis

Tue 2/17

6:00 am-1:09 pm

1 stop7h 09m

$245

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 4/1

5:35 am-11:55 am

1 stop6h 20m

Mobile

Wed 4/8

6:00 am-10:39 am

1 stop4h 39m

$249

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Thu 1/22

5:16 pm-10:01 pm

1 stop4h 45m

Baton Rouge Ryan

Tue 1/27

5:00 pm-10:29 pm

1 stop5h 29m

$249

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Sat 1/24

6:24 am-4:19 pm

2 stops9h 55m

Baton Rouge Ryan

Tue 1/27

5:00 pm-10:29 pm

1 stop5h 29m

$254

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Sat 1/17

11:30 am-9:32 pm

2 stops10h 02m

Baton Rouge Ryan

Wed 1/21

9:30 am-8:34 pm

2 stops11h 04m

$309

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sun 1/25

8:30 am-12:31 pm

1 stop28h 01m

Memphis

Sun 2/1

8:18 pm-10:19 am

2 stops14h 01m

$316

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 1/24

8:10 am-4:09 pm

1 stop7h 59m

Mobile

Wed 1/28

4:50 pm-10:30 pm

1 stop5h 40m

$319

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sun 1/25

2:58 pm-10:49 am

2 stops19h 51m

Memphis

Sun 2/1

8:18 pm-10:19 am

2 stops14h 01m

$319

Des MoinesJackson

DSM - JAN

DSMJAN

Des Moines

Thu 1/8

8:35 am-8:00 pm

2 stops11h 25m

Jackson-Evers Intl

Sun 1/11

11:50 am-9:20 pm

2 stops9h 30m

$383

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Mississippi?

The cheapest day to depart from Des Moines to Mississippi is on a Saturday. Travelers who choose to depart for Mississippi on a Saturday will often find tickets for as low as $296. Flights from Des Moines to Mississippi on a Wednesday will generally be more expensive and average around $508. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Mississippi?

According to our data, the cheapest time of day to fly to Mississippi is in the afternoon. momondo users have found flights departing from Des Moines to Mississippi in the afternoon for as low as $296. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. At noon is when there is more demand to fly to Mississippi, so prices are often more expensive at around $560 per ticket.

Can stopping save me money on Des Moines to Mississippi flights?

You could potentially save up to 27% on your flight if you consider stops on a Des Moines to Mississippi flight.

Cheap Des Moines to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mississippi

Fastest flight time	4h 32m
Direct flights	None

The fastest flight from Des Moines to Mississippi takes 4h 32m

There are no direct flights from Des Moines to Mississippi. There are no popular flight routes from Des Moines to Mississippi.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Mississippi?
Prices for flights from Des Moines Airport to Mississippi refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Mississippi?
There are 3 operators available for flights from Des Moines Airport to Mississippi as of December 2025.
How old do you have to be to fly from Des Moines Airport to Mississippi?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mississippi

Compare and see reviews for airlines that fly from Des Moines to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,050 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mississippi?

Finding the right flight to Mississippi from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mississippi quick and easy, saving you time and money.

Can I find flights from Des Moines to Mississippi with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Mississippi flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Mississippi?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mississippi from Des Moines.

I’m not ready to book a flight from Des Moines to Mississippi right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Mississippi now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mississippi and let you know when they change.