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Cheap flights from Des Moines to Memphis from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Memphis departing on 1/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Memphis

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
2:59 pm - 9:59 pmDSM-MEM
7h 00m1 stop
United Airlines Logo
9:55 am - 2:27 pmMEM-DSM
4h 32m1 stop
$246United Airlines
Find Deal
Wed, Feb 18 - Thu, Feb 19
Delta Logo
6:50 am - 11:25 amDSM-MEM
4h 35m1 stop
Delta Logo
5:05 pm - 10:34 pmMEM-DSM
5h 29m1 stop
$251Delta
Find Deal
Tue, Dec 2 - Sat, Dec 6
Southwest Logo
6:10 am - 5:10 pmDSM-MEM
11h 00m2 stops
Southwest Logo
7:30 am - 4:00 pmMEM-DSM
8h 30m1 stop
$256Southwest
Find Deal
Wed, Feb 18 - Thu, Feb 19
Southwest Logo
6:10 am - 5:10 pmDSM-MEM
11h 00m2 stops
Southwest Logo
2:35 pm - 10:15 pmMEM-DSM
7h 40m2 stops
$261Southwest
Find Deal
Wed, Feb 18 - Thu, Feb 19
Multiple Airlines Logo
6:53 pm - 9:02 amDSM-MEM
38h 09m2 stops
Multiple Airlines Logo
3:16 pm - 9:48 amMEM-DSM
18h 32m1 stop
$278Multiple Airlines
Find Deal
Mon, Dec 1 - Fri, Dec 5
American Airlines Logo
6:52 pm - 11:59 pmDSM-MEM
5h 07m1 stop
American Airlines Logo
8:37 am - 4:24 pmMEM-DSM
7h 47m2 stops
$284American Airlines
Find Deal
Tue, Dec 30 - Tue, Jan 6
Delta Logo
2:16 pm - 6:31 pmDSM-MEM
4h 15m1 stop
Delta Logo
9:16 am - 1:31 pmMEM-DSM
4h 15m1 stop
$289Delta
Find Deal
Tue, Dec 16 - Thu, Dec 18
American Airlines Logo
12:57 pm - 9:58 pmDSM-MEM
9h 01m1 stop
American Airlines Logo
7:05 am - 3:24 pmMEM-DSM
8h 19m2 stops
$294American Airlines
Find Deal
Tue, Dec 16 - Thu, Dec 18
American Airlines Logo
1:17 pm - 8:55 pmDSM-MEM
7h 38m2 stops
American Airlines Logo
7:05 am - 3:24 pmMEM-DSM
8h 19m2 stops
$299American Airlines
Find Deal
Tue, Dec 16 - Thu, Dec 18
American Airlines Logo
10:00 am - 7:53 pmDSM-MEM
9h 53m2 stops
American Airlines Logo
5:38 am - 10:46 amMEM-DSM
5h 08m1 stop
$318American Airlines
Find Deal
Fri, Feb 20 - Sun, Feb 22

United Airlines flights from Des Moines to Memphis

Our best United Airlines deals on Des Moines to Memphis flight tickets
United Airlines
Feb 18
DSM2:59 pmDes Moines
7h 00m
1 stop
MEM9:59 pmMemphis
Feb 19
MEM9:55 amMemphis
4h 32m
1 stop
DSM2:27 pmDes Moines
$246
Find similar
United Airlines
Nov 21
DSM9:01 amDes Moines
5h 21m
1 stop
MEM2:22 pmMemphis
Nov 24
MEM3:26 pmMemphis
6h 54m
1 stop
DSM10:20 pmDes Moines
$424
Find similar
United Airlines
Nov 21
DSM5:45 amDes Moines
8h 14m
2 stops
MEM1:59 pmMemphis
Nov 24
MEM3:25 pmMemphis
8h 19m
1 stop
DSM11:44 pmDes Moines
$429
Find similar

Southwest flights from Des Moines to Memphis

Our best Southwest deals on Des Moines to Memphis flight tickets
Southwest
Feb 18
DSM6:10 amDes Moines
11h 00m
2 stops
MEM5:10 pmMemphis
Feb 19
MEM7:30 amMemphis
8h 30m
1 stop
DSM4:00 pmDes Moines
$256
Find similar
Southwest
Feb 18
DSM6:10 amDes Moines
11h 00m
2 stops
MEM5:10 pmMemphis
Feb 19
MEM2:35 pmMemphis
7h 40m
2 stops
DSM10:15 pmDes Moines
$261
Find similar
Southwest
Feb 20
DSM5:10 amDes Moines
10h 00m
2 stops
MEM3:10 pmMemphis
Feb 22
MEM12:00 pmMemphis
11h 35m
2 stops
DSM11:35 pmDes Moines
$340
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 2/18

2:59 pm-9:59 pm

1 stop7h 00m

Memphis

Thu 2/19

9:55 am-2:27 pm

1 stop4h 32m

$246

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 12/2

6:50 am-11:25 am

1 stop4h 35m

Memphis

Sat 12/6

5:05 pm-10:34 pm

1 stop5h 29m

$251

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 2/18

6:10 am-5:10 pm

2 stops11h 00m

Memphis

Thu 2/19

7:30 am-4:00 pm

1 stop8h 30m

$256

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 2/18

6:10 am-5:10 pm

2 stops11h 00m

Memphis

Thu 2/19

2:35 pm-10:15 pm

2 stops7h 40m

$261

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 12/1

6:53 pm-9:02 am

2 stops38h 09m

Memphis

Fri 12/5

3:16 pm-9:48 am

1 stop18h 32m

$278

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 12/30

6:52 pm-11:59 pm

1 stop5h 07m

Memphis

Tue 1/6

8:37 am-4:24 pm

2 stops7h 47m

$284

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 12/16

2:16 pm-6:31 pm

1 stop4h 15m

Memphis

Thu 12/18

9:16 am-1:31 pm

1 stop4h 15m

$289

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 12/16

12:57 pm-9:58 pm

1 stop9h 01m

Memphis

Thu 12/18

7:05 am-3:24 pm

2 stops8h 19m

$294

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 12/16

1:17 pm-8:55 pm

2 stops7h 38m

Memphis

Thu 12/18

7:05 am-3:24 pm

2 stops8h 19m

$299

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 2/20

10:00 am-7:53 pm

2 stops9h 53m

Memphis

Sun 2/22

5:38 am-10:46 am

1 stop5h 08m

$318

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Memphis from

How to get the cheapest flight ticket from Des Moines to Memphis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Memphis?

According to our data, Saturday is the cheapest day to fly to Memphis from Des Moines. The lowest ticket price found for a Saturday departure recently was $263. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Memphis for around $424.

What is the cheapest time of day to depart on your flight to Memphis?

Our data shows that the cheapest Des Moines to Memphis flights are usually those with departure times in the afternoon. Our users have found flights to Memphis in the afternoon for as low as $322. Try not to purchase tickets in the morning because they tend to be around $366. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Des Moines to Memphis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Memphis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Memphis (DSM to MEM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Memphis

Direct flights

None
There are no direct flights from Des Moines to Memphis. There are no popular flight routes from Des Moines to Memphis.
Search flight deals

  • How far is Des Moines to Memphis by plane?

    Des Moines and Memphis are 484.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 15m.

  • When did momondo last update prices for flights from Des Moines Airport to Memphis Airport?

    Prices for flights from Des Moines Airport to Memphis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Memphis Airport?

  • How old do you have to be to fly from Des Moines Airport to Memphis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Memphis Airport.

  • What documentation or ID do you need to fly to Memphis Airport?

    The travel and health documents you'll need for your trip to Memphis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Memphis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Memphis?

Best airlines flying from Des Moines to Memphis

Compare and see reviews for airlines that fly from Des Moines to Memphis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $252Free CancellationRating
7.2
11,048 reviews
Search American Airlines flights
DeltaPriceFrom $257Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Southaven
Tunica
Germantown
West Memphis
Forrest City
Batesville
Horn Lake
Cordova
Marion
Osceola

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Memphis?

Finding the right flight to Memphis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Memphis quick and easy, saving you time and money.

Can I find flights from Des Moines to Memphis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Memphis from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Memphis?

Once all potential Des Moines to Memphis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Memphis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Memphis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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