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Cheap flights from Des Moines to Memphis from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Memphis departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Memphis

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:00 am - 11:05 am
DSM
-
MEM
6h 05m
1 stop
United Airlines Logo
8:45 am - 4:15 pm
MEM
-
DSM
7h 30m
1 stop
$278United Airlines
Sat, May 30 - Tue, Jun 2
American Airlines Logo
1:48 pm - 9:13 pm
DSM
-
MEM
7h 25m
1 stop
American Airlines Logo
5:00 am - 1:18 pm
MEM
-
DSM
8h 18m
2 stops
$283American Airlines
Sat, May 30 - Tue, Jun 2
Southwest Logo
5:35 am - 3:45 pm
DSM
-
MEM
10h 10m
2 stops
Southwest Logo
12:20 pm - 9:15 pm
MEM
-
DSM
8h 55m
2 stops
$319Southwest
Sat, May 30 - Tue, Jun 2
Delta Logo
10:26 am - 5:05 pm
DSM
-
MEM
6h 39m
1 stop
Delta Logo
10:36 am - 4:48 pm
MEM
-
DSM
6h 12m
1 stop
$322Delta
Mon, May 18 - Thu, May 21
United Airlines Logo
10:02 am - 2:39 pm
DSM
-
MEM
4h 37m
1 stop
United Airlines Logo
8:40 am - 4:15 pm
MEM
-
DSM
7h 35m
1 stop
$341United Airlines
Sat, May 9 - Wed, May 13
United Airlines Logo
6:15 am - 6:15 pm
DSM
-
MEM
12h 00m
2 stops
United Airlines Logo
8:40 am - 4:15 pm
MEM
-
DSM
7h 35m
1 stop
$346United Airlines
Sat, May 9 - Wed, May 13
Southwest Logo
5:25 am - 11:40 am
DSM
-
MEM
6h 15m
1 stop
Southwest Logo
4:10 pm - 11:05 pm
MEM
-
DSM
6h 55m
1 stop
$355Southwest
Mon, May 18 - Thu, May 21
Southwest Logo
5:25 am - 11:40 am
DSM
-
MEM
6h 15m
1 stop
Southwest Logo
12:30 pm - 11:05 pm
MEM
-
DSM
10h 35m
2 stops
$360Southwest
Mon, May 18 - Thu, May 21
Southwest Logo
5:25 am - 11:40 am
DSM
-
MEM
6h 15m
1 stop
Southwest Logo
12:20 pm - 9:55 pm
MEM
-
DSM
9h 35m
2 stops
$372Southwest
Mon, May 18 - Thu, May 21
United Airlines Logo
8:00 am - 2:39 pm
DSM
-
MEM
6h 39m
1 stop
United Airlines Logo
3:20 pm - 10:45 pm
MEM
-
DSM
7h 25m
1 stop
$376United Airlines
Sat, May 9 - Wed, May 13

United Airlines flights from Des Moines to Memphis

Our best United Airlines deals on Des Moines to Memphis flight tickets
United Airlines
May 30
DSM5:00 amDes Moines
6h 05m
1 stop
MEM11:05 amMemphis
Jun 2
MEM8:45 amMemphis
7h 30m
1 stop
DSM4:15 pmDes Moines
$278
United Airlines
May 9
DSM10:02 amDes Moines
4h 37m
1 stop
MEM2:39 pmMemphis
May 13
MEM8:40 amMemphis
7h 35m
1 stop
DSM4:15 pmDes Moines
$341
United Airlines
May 9
DSM6:15 amDes Moines
12h 00m
2 stops
MEM6:15 pmMemphis
May 13
MEM8:40 amMemphis
7h 35m
1 stop
DSM4:15 pmDes Moines
$346

Southwest flights from Des Moines to Memphis

Our best Southwest deals on Des Moines to Memphis flight tickets
Southwest
May 30
DSM5:35 amDes Moines
10h 10m
2 stops
MEM3:45 pmMemphis
Jun 2
MEM12:20 pmMemphis
8h 55m
2 stops
DSM9:15 pmDes Moines
$319
Southwest
May 18
DSM5:25 amDes Moines
6h 15m
1 stop
MEM11:40 amMemphis
May 21
MEM4:10 pmMemphis
6h 55m
1 stop
DSM11:05 pmDes Moines
$355
Southwest
May 18
DSM5:25 amDes Moines
6h 15m
1 stop
MEM11:40 amMemphis
May 21
MEM12:30 pmMemphis
10h 35m
2 stops
DSM11:05 pmDes Moines
$360

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 15, 2026.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 5/30

5:00 am-11:05 am

1 stop6h 05m

Memphis

Tue 6/2

8:45 am-4:15 pm

1 stop7h 30m

$278

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 5/30

1:48 pm-9:13 pm

1 stop7h 25m

Memphis

Tue 6/2

5:00 am-1:18 pm

2 stops8h 18m

$283

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 5/30

5:35 am-3:45 pm

2 stops10h 10m

Memphis

Tue 6/2

12:20 pm-9:15 pm

2 stops8h 55m

$319

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 5/18

10:26 am-5:05 pm

1 stop6h 39m

Memphis

Thu 5/21

10:36 am-4:48 pm

1 stop6h 12m

$322
Quickest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 5/9

10:02 am-2:39 pm

1 stop4h 37m

Memphis

Wed 5/13

8:40 am-4:15 pm

1 stop7h 35m

$341

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 5/9

6:15 am-6:15 pm

2 stops12h 00m

Memphis

Wed 5/13

8:40 am-4:15 pm

1 stop7h 35m

$346

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 5/18

5:25 am-11:40 am

1 stop6h 15m

Memphis

Thu 5/21

4:10 pm-11:05 pm

1 stop6h 55m

$355

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 5/18

5:25 am-11:40 am

1 stop6h 15m

Memphis

Thu 5/21

12:30 pm-11:05 pm

2 stops10h 35m

$360

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 5/18

5:25 am-11:40 am

1 stop6h 15m

Memphis

Thu 5/21

12:20 pm-9:55 pm

2 stops9h 35m

$372

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 5/9

8:00 am-2:39 pm

1 stop6h 39m

Memphis

Wed 5/13

3:20 pm-10:45 pm

1 stop7h 25m

$376

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Memphis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Memphis?

When to book flights from Des Moines to Memphis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Memphis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Memphis (DSM to MEM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Memphis

Fastest flight time

6h 45m

Direct flights

None
The fastest flight from Des Moines to Memphis takes 6h 45m
There are no direct flights from Des Moines to Memphis. There are no popular flight routes from Des Moines to Memphis.
Search flight deals

Frequently asked questions about flying from Des Moines to Memphis

  • How far is Des Moines to Memphis by plane?

    Des Moines and Memphis are 484.7 mi apart from one another. In terms of flight time, this usually takes a little over 6h 45m.

  • When did momondo last update prices for flights from Des Moines Airport to Memphis Airport?

    Prices for flights from Des Moines Airport to Memphis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Memphis Airport?

  • How old do you have to be to fly from Des Moines Airport to Memphis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Memphis Airport.

  • What documentation or ID do you need to fly to Memphis Airport?

    The travel and health documents you'll need for your trip to Memphis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Memphis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Memphis?

Best airlines flying from Des Moines to Memphis

Compare and see reviews for airlines that fly from Des Moines to Memphis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $263Free CancellationRating
7.1
11,580 reviews
Search American Airlines flights
DeltaPriceFrom $263Free CancellationRating
7.9
8,404 reviews
Search Delta flights

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Southaven
Tunica
Germantown
West Memphis
Batesville
Forrest City
Cordova
Horn Lake
Marion
Osceola

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Memphis?

Finding the right flight to Memphis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Memphis quick and easy, saving you time and money.

Can I find flights from Des Moines to Memphis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Memphis from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Memphis?

Once all potential Des Moines to Memphis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Memphis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Memphis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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