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Cheap flights from Des Moines to Memphis from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Memphis departing on 11/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Memphis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:00 am - 1:12 pmDSM-MEM
28h 12m2 stops
Multiple Airlines Logo
8:07 pm - 7:03 pmMEM-DSM
22h 56m1 stop
$244Multiple Airlines
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Thu, Nov 27 - Thu, Dec 4
American Airlines Logo
6:35 pm - 11:57 pmDSM-MEM
5h 22m1 stop
American Airlines Logo
7:04 am - 12:48 pmMEM-DSM
5h 44m1 stop
$251American Airlines
Find Deal
Thu, Dec 18 - Mon, Dec 22
American Airlines Logo
6:56 pm - 11:59 pmDSM-MEM
5h 03m1 stop
American Airlines Logo
4:40 pm - 11:48 pmMEM-DSM
7h 08m1 stop
$275American Airlines
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Wed, Nov 26 - Wed, Dec 3
Multiple Airlines Logo
7:28 pm - 2:54 pmDSM-MEM
19h 26m1 stop
Multiple Airlines Logo
3:01 pm - 2:42 pmMEM-DSM
23h 41m1 stop
$293Multiple Airlines
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Fri, Dec 12 - Fri, Dec 19
Delta Logo
12:00 pm - 6:00 pmDSM-MEM
6h 00m1 stop
Delta Logo
8:05 am - 1:31 pmMEM-DSM
5h 26m1 stop
$299Delta
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Thu, Nov 27 - Thu, Dec 4
Delta Logo
5:34 am - 11:42 amDSM-MEM
6h 08m1 stop
Delta Logo
5:55 am - 10:21 amMEM-DSM
4h 26m1 stop
$327Delta
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Fri, Dec 12 - Fri, Dec 19
Southwest Logo
5:45 am - 3:45 pmDSM-MEM
10h 00m2 stops
Southwest Logo
3:00 pm - 9:35 pmMEM-DSM
6h 35m2 stops
$329Southwest
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Thu, Nov 27 - Thu, Dec 4
Southwest Logo
8:00 am - 4:10 pmDSM-MEM
8h 10m1 stop
Southwest Logo
1:30 pm - 12:05 amMEM-DSM
10h 35m2 stops
$330Southwest
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Thu, Dec 18 - Mon, Dec 22
United Airlines Logo
5:45 am - 1:19 pmDSM-MEM
7h 34m1 stop
United Airlines Logo
7:30 am - 12:14 pmMEM-DSM
4h 44m1 stop
$507United Airlines
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Wed, Nov 12 - Sun, Nov 16
United Airlines Logo
8:02 am - 8:32 pmDSM-MEM
12h 30m2 stops
United Airlines Logo
7:30 am - 12:14 pmMEM-DSM
4h 44m1 stop
$512United Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16

United Airlines flights from Des Moines to Memphis

Our best United Airlines deals on Des Moines to Memphis flight tickets
United Airlines
Nov 12
DSM5:45 amDes Moines
7h 34m
1 stop
MEM1:19 pmMemphis
Nov 16
MEM7:30 amMemphis
4h 44m
1 stop
DSM12:14 pmDes Moines
$507
Find similar
United Airlines
Nov 12
DSM8:02 amDes Moines
12h 30m
2 stops
MEM8:32 pmMemphis
Nov 16
MEM7:30 amMemphis
4h 44m
1 stop
DSM12:14 pmDes Moines
$512
Find similar
United Airlines
Oct 31
DSM1:05 pmDes Moines
8h 36m
2 stops
MEM9:41 pmMemphis
Nov 7
MEM6:45 amMemphis
10h 40m
2 stops
DSM5:25 pmDes Moines
$604
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Delta flights from Des Moines to Memphis

Our best Delta deals on Des Moines to Memphis flight tickets
Delta
Nov 27
DSM12:00 pmDes Moines
6h 00m
1 stop
MEM6:00 pmMemphis
Dec 4
MEM8:05 amMemphis
5h 26m
1 stop
DSM1:31 pmDes Moines
$299
Find similar
Delta
Dec 12
DSM5:34 amDes Moines
6h 08m
1 stop
MEM11:42 amMemphis
Dec 19
MEM5:55 amMemphis
4h 26m
1 stop
DSM10:21 amDes Moines
$327
Find similar
Delta
Nov 14
DSM4:59 pmDes Moines
5h 34m
1 stop
MEM10:33 pmMemphis
Nov 18
MEM5:56 pmMemphis
4h 37m
1 stop
DSM10:33 pmDes Moines
$407
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momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 11/27

9:00 am-1:12 pm

2 stops28h 12m

Memphis

Thu 12/4

8:07 pm-7:03 pm

1 stop22h 56m

$244

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 12/18

6:35 pm-11:57 pm

1 stop5h 22m

Memphis

Mon 12/22

7:04 am-12:48 pm

1 stop5h 44m

$251

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 11/26

6:56 pm-11:59 pm

1 stop5h 03m

Memphis

Wed 12/3

4:40 pm-11:48 pm

1 stop7h 08m

$275

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 12/12

7:28 pm-2:54 pm

1 stop19h 26m

Memphis

Fri 12/19

3:01 pm-2:42 pm

1 stop23h 41m

$293

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 11/27

12:00 pm-6:00 pm

1 stop6h 00m

Memphis

Thu 12/4

8:05 am-1:31 pm

1 stop5h 26m

$299

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 12/12

5:34 am-11:42 am

1 stop6h 08m

Memphis

Fri 12/19

5:55 am-10:21 am

1 stop4h 26m

$327

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 11/27

5:45 am-3:45 pm

2 stops10h 00m

Memphis

Thu 12/4

3:00 pm-9:35 pm

2 stops6h 35m

$329

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 12/18

8:00 am-4:10 pm

1 stop8h 10m

Memphis

Mon 12/22

1:30 pm-12:05 am

2 stops10h 35m

$330

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 11/12

5:45 am-1:19 pm

1 stop7h 34m

Memphis

Sun 11/16

7:30 am-12:14 pm

1 stop4h 44m

$507

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 11/12

8:02 am-8:32 pm

2 stops12h 30m

Memphis

Sun 11/16

7:30 am-12:14 pm

1 stop4h 44m

$512

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Memphis from

How to get the cheapest flight ticket from Des Moines to Memphis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Memphis?

According to our data, Saturday is the cheapest day to fly to Memphis from Des Moines. The lowest ticket price found for a Saturday departure recently was $263. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Memphis for around $424.

What is the cheapest time of day to depart on your flight to Memphis?

Our data shows that the cheapest Des Moines to Memphis flights are usually those with departure times in the afternoon. Our users have found flights to Memphis in the afternoon for as low as $322. Try not to purchase tickets in the morning because they tend to be around $366. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Des Moines to Memphis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Memphis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Memphis (DSM to MEM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Memphis

Direct flights

None
There are no direct flights from Des Moines to Memphis. There are no popular flight routes from Des Moines to Memphis.
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  • How far is Des Moines to Memphis by plane?

    Des Moines and Memphis are 484.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 28m.

  • When did momondo last update prices for flights from Des Moines Airport to Memphis Airport?

    Prices for flights from Des Moines Airport to Memphis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Memphis Airport?

  • How old do you have to be to fly from Des Moines Airport to Memphis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Memphis Airport.

  • What documentation or ID do you need to fly to Memphis Airport?

    The travel and health documents you'll need for your trip to Memphis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Memphis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Memphis?

Best airlines flying from Des Moines to Memphis

Compare and see reviews for airlines that fly from Des Moines to Memphis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $252Free CancellationRating
7.2
11,035 reviews
Search American Airlines flights
DeltaPriceFrom $257Free CancellationRating
7.9
7,998 reviews
Search Delta flights

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Southaven
Tunica
Germantown
West Memphis
Forrest City
Batesville
Horn Lake
Cordova
Marion
Osceola

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Memphis?

Finding the right flight to Memphis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Memphis quick and easy, saving you time and money.

Can I find flights from Des Moines to Memphis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Memphis from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Memphis?

Once all potential Des Moines to Memphis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Memphis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Memphis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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