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Cheap flights from Des Moines to Memphis from $141

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Memphis departing on 7/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Memphis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
4:40 pm - 11:05 pm
DSM
-
MEM
6h 25m
1 stop
Southwest Logo
5:20 am - 11:30 am
MEM
-
DSM
6h 10m
1 stop
$314Southwest
Fri, Jun 26 - Tue, Jun 30
American Airlines Logo
5:30 am - 11:09 am
DSM
-
MEM
5h 39m
1 stop
American Airlines Logo
5:00 am - 1:21 pm
MEM
-
DSM
8h 21m
2 stops
$319American Airlines
Fri, Jun 26 - Tue, Jun 30
Allegiant Air Logo
6:44 pm - 8:05 am
DSM
-
MEM
13h 21m
1 stop
Allegiant Air Logo
8:23 am - 5:54 pm
MEM
-
DSM
9h 31m
1 stop
$323Allegiant Air
Fri, Jun 19 - Mon, Jun 22
Southwest Logo
3:50 pm - 10:25 pm
DSM
-
MEM
6h 35m
1 stop
Southwest Logo
5:15 am - 11:25 am
MEM
-
DSM
6h 10m
1 stop
$333Southwest
Fri, Aug 7 - Mon, Aug 10
Southwest Logo
2:25 pm - 9:30 pm
DSM
-
MEM
7h 05m
1 stop
Southwest Logo
12:20 pm - 10:10 pm
MEM
-
DSM
9h 50m
2 stops
$338Southwest
Fri, Aug 7 - Mon, Aug 10
Southwest Logo
4:40 pm - 11:10 pm
DSM
-
MEM
6h 30m
1 stop
Southwest Logo
3:20 pm - 10:10 pm
MEM
-
DSM
6h 50m
1 stop
$347Southwest
Mon, Aug 3 - Fri, Aug 7
Southwest Logo
4:40 pm - 11:10 pm
DSM
-
MEM
6h 30m
1 stop
Southwest Logo
2:55 pm - 10:10 pm
MEM
-
DSM
7h 15m
2 stops
$352Southwest
Mon, Aug 3 - Fri, Aug 7
Southwest Logo
5:40 am - 4:10 pm
DSM
-
MEM
10h 30m
2 stops
Southwest Logo
2:55 pm - 10:10 pm
MEM
-
DSM
7h 15m
2 stops
$353Southwest
Fri, Aug 7 - Mon, Aug 10
Southwest Logo
5:10 am - 3:35 pm
DSM
-
MEM
10h 25m
2 stops
Southwest Logo
2:55 pm - 10:10 pm
MEM
-
DSM
7h 15m
2 stops
$357Southwest
Mon, Aug 3 - Fri, Aug 7
United Airlines Logo
1:35 pm - 8:42 pm
DSM
-
MEM
7h 07m
1 stop
United Airlines Logo
7:15 am - 2:20 pm
MEM
-
DSM
7h 05m
1 stop
$366United Airlines
Wed, Sep 16 - Sat, Sep 19

Allegiant Air flights from Des Moines to Memphis

Our best Allegiant Air deals on Des Moines to Memphis flight tickets
Allegiant Air
Jun 19
DSM6:44 pmDes Moines
13h 21m
1 stop
MEM8:05 amMemphis
Jun 22
MEM8:23 amMemphis
9h 31m
1 stop
DSM5:54 pmDes Moines
$323
Allegiant Air
Jun 18
DSM6:00 amDes Moines
25h 33m
2 stops
MEM7:33 amMemphis
Jun 22
MEM8:23 amMemphis
9h 31m
1 stop
DSM5:54 pmDes Moines
$381
Allegiant Air
Jun 5
DSM4:07 pmDes Moines
18h 33m
1 stop
MEM10:40 amMemphis
Jun 12
MEM8:23 amMemphis
9h 31m
1 stop
DSM5:54 pmDes Moines
$489

Southwest flights from Des Moines to Memphis

Our best Southwest deals on Des Moines to Memphis flight tickets
Southwest
Jun 26
DSM4:40 pmDes Moines
6h 25m
1 stop
MEM11:05 pmMemphis
Jun 30
MEM5:20 amMemphis
6h 10m
1 stop
DSM11:30 amDes Moines
$314
Southwest
Aug 7
DSM3:50 pmDes Moines
6h 35m
1 stop
MEM10:25 pmMemphis
Aug 10
MEM5:15 amMemphis
6h 10m
1 stop
DSM11:25 amDes Moines
$333
Southwest
Aug 7
DSM2:25 pmDes Moines
7h 05m
1 stop
MEM9:30 pmMemphis
Aug 10
MEM12:20 pmMemphis
9h 50m
2 stops
DSM10:10 pmDes Moines
$338

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 29, 2026.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 6/26

4:40 pm-11:05 pm

1 stop6h 25m

Memphis

Tue 6/30

5:20 am-11:30 am

1 stop6h 10m

$314

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 6/26

5:30 am-11:09 am

1 stop5h 39m

Memphis

Tue 6/30

5:00 am-1:21 pm

2 stops8h 21m

$319

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 6/19

6:44 pm-8:05 am

1 stop13h 21m

Memphis

Mon 6/22

8:23 am-5:54 pm

1 stop9h 31m

$323

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 8/7

3:50 pm-10:25 pm

1 stop6h 35m

Memphis

Mon 8/10

5:15 am-11:25 am

1 stop6h 10m

$333

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 8/7

2:25 pm-9:30 pm

1 stop7h 05m

Memphis

Mon 8/10

12:20 pm-10:10 pm

2 stops9h 50m

$338

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 8/3

4:40 pm-11:10 pm

1 stop6h 30m

Memphis

Fri 8/7

3:20 pm-10:10 pm

1 stop6h 50m

$347

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 8/3

4:40 pm-11:10 pm

1 stop6h 30m

Memphis

Fri 8/7

2:55 pm-10:10 pm

2 stops7h 15m

$352

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 8/7

5:40 am-4:10 pm

2 stops10h 30m

Memphis

Mon 8/10

2:55 pm-10:10 pm

2 stops7h 15m

$353

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 8/3

5:10 am-3:35 pm

2 stops10h 25m

Memphis

Fri 8/7

2:55 pm-10:10 pm

2 stops7h 15m

$357

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 9/16

1:35 pm-8:42 pm

1 stop7h 07m

Memphis

Sat 9/19

7:15 am-2:20 pm

1 stop7h 05m

$366

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Memphis from

How to get the cheapest flight ticket from Des Moines to Memphis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Memphis?

What is the cheapest month to fly to Memphis?

If you aren’t able to travel to Memphis during the month of August, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $0.

When to book flights from Des Moines to Memphis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Memphis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Memphis (DSM to MEM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Memphis

Fastest flight time

4h 30m

Direct flights

None
The fastest flight from Des Moines to Memphis takes 4h 30m
There are no direct flights from Des Moines to Memphis. There are no popular flight routes from Des Moines to Memphis.
Search flight deals

Frequently asked questions about flying from Des Moines to Memphis

  • How far is Des Moines to Memphis by plane?

    Des Moines and Memphis are 484.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 30m.

  • When did momondo last update prices for flights from Des Moines Airport to Memphis Airport?

    Prices for flights from Des Moines Airport to Memphis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Memphis Airport?

  • How old do you have to be to fly from Des Moines Airport to Memphis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Memphis Airport.

  • What documentation or ID do you need to fly to Memphis Airport?

    The travel and health documents you'll need for your trip to Memphis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Memphis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Memphis?

Best airlines flying from Des Moines to Memphis

Compare and see reviews for airlines that fly from Des Moines to Memphis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $263Free CancellationRating
7.1
11,643 reviews
Search American Airlines flights
DeltaPriceFrom $263Free CancellationRating
7.9
8,419 reviews
Search Delta flights

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Southaven
Tunica
Germantown
West Memphis
Batesville
Forrest City
Cordova
Horn Lake
Osceola
Marion

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Memphis?

Finding the right flight to Memphis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Memphis quick and easy, saving you time and money.

Can I find flights from Des Moines to Memphis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Memphis from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Memphis?

Once all potential Des Moines to Memphis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Memphis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Memphis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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