Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Memphis from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Memphis departing on 3/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Memphis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
3:40 pm - 10:25 pm
DSM
-
MEM
6h 45m
1 stop
Southwest Logo
3:25 pm - 10:05 pm
MEM
-
DSM
6h 40m
1 stop
$251Southwest
Wed, Mar 25 - Tue, Mar 31
Southwest Logo
6:40 am - 1:55 pm
DSM
-
MEM
7h 15m
1 stop
Southwest Logo
1:10 pm - 10:05 pm
MEM
-
DSM
8h 55m
2 stops
$256Southwest
Wed, Mar 25 - Tue, Mar 31
Southwest Logo
5:30 am - 3:20 pm
DSM
-
MEM
9h 50m
2 stops
Southwest Logo
5:30 am - 1:15 pm
MEM
-
DSM
7h 45m
2 stops
$261Southwest
Wed, Mar 25 - Tue, Mar 31
Delta Logo
6:55 am - 11:47 am
DSM
-
MEM
4h 52m
1 stop
Delta Logo
5:37 pm - 10:38 pm
MEM
-
DSM
5h 01m
1 stop
$264Delta
Tue, Mar 24 - Mon, Mar 30
Southwest Logo
3:40 pm - 10:25 pm
DSM
-
MEM
6h 45m
1 stop
Southwest Logo
2:55 pm - 11:15 pm
MEM
-
DSM
8h 20m
2 stops
$269Southwest
Wed, Mar 25 - Mon, Mar 30
Southwest Logo
5:30 am - 3:20 pm
DSM
-
MEM
9h 50m
2 stops
Southwest Logo
2:55 pm - 11:15 pm
MEM
-
DSM
8h 20m
2 stops
$274Southwest
Wed, Mar 25 - Mon, Mar 30
Delta Logo
6:55 am - 11:47 am
DSM
-
MEM
4h 52m
1 stop
Delta Logo
5:37 pm - 10:38 pm
MEM
-
DSM
5h 01m
1 stop
$277Delta
Thu, Mar 26 - Sat, Mar 28
American Airlines Logo
1:37 pm - 6:47 pm
DSM
-
MEM
5h 10m
1 stop
American Airlines Logo
6:11 pm - 11:46 pm
MEM
-
DSM
5h 35m
1 stop
$278American Airlines
Sat, Mar 28 - Sat, Apr 4
Delta Logo
4:25 pm - 8:26 pm
DSM
-
MEM
4h 01m
1 stop
Delta Logo
12:07 pm - 4:33 pm
MEM
-
DSM
4h 26m
1 stop
$289Delta
Fri, Mar 27 - Tue, Mar 31
Delta Logo
4:25 pm - 8:26 pm
DSM
-
MEM
4h 01m
1 stop
Delta Logo
10:34 am - 4:33 pm
MEM
-
DSM
5h 59m
1 stop
$302Delta
Fri, Mar 27 - Sat, Mar 28

American Airlines flights from Des Moines to Memphis

Our best American Airlines deals on Des Moines to Memphis flight tickets
American Airlines
Mar 28
DSM1:37 pmDes Moines
5h 10m
1 stop
MEM6:47 pmMemphis
Apr 4
MEM6:11 pmMemphis
5h 35m
1 stop
DSM11:46 pmDes Moines
$278
American Airlines
Mar 28
DSM7:44 pmDes Moines
4h 15m
1 stop
MEM11:59 pmMemphis
Apr 4
MEM9:26 amMemphis
5h 30m
1 stop
DSM2:56 pmDes Moines
$303
American Airlines
Mar 28
DSM10:04 amDes Moines
13h 55m
1 stop
MEM11:59 pmMemphis
Mar 31
MEM7:23 pmMemphis
4h 25m
1 stop
DSM11:48 pmDes Moines
$325

United Airlines flights from Des Moines to Memphis

Our best United Airlines deals on Des Moines to Memphis flight tickets
United Airlines
Mar 24
DSM11:26 amDes Moines
10h 08m
2 stops
MEM9:34 pmMemphis
Mar 28
MEM7:30 amMemphis
14h 10m
1 stop
DSM9:40 pmDes Moines
$333
United Airlines
Mar 24
DSM11:26 amDes Moines
10h 08m
2 stops
MEM9:34 pmMemphis
Mar 30
MEM6:32 pmMemphis
4h 27m
1 stop
DSM10:59 pmDes Moines
$342
United Airlines
Mar 28
DSM8:00 amDes Moines
13h 59m
1 stop
MEM9:59 pmMemphis
Mar 29
MEM7:30 amMemphis
4h 59m
1 stop
DSM12:29 pmDes Moines
$353

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 3/25

3:40 pm-10:25 pm

1 stop6h 45m

Memphis

Tue 3/31

3:25 pm-10:05 pm

1 stop6h 40m

$251

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 3/25

6:40 am-1:55 pm

1 stop7h 15m

Memphis

Tue 3/31

1:10 pm-10:05 pm

2 stops8h 55m

$256

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 3/25

5:30 am-3:20 pm

2 stops9h 50m

Memphis

Tue 3/31

5:30 am-1:15 pm

2 stops7h 45m

$261

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 3/24

6:55 am-11:47 am

1 stop4h 52m

Memphis

Mon 3/30

5:37 pm-10:38 pm

1 stop5h 01m

$264

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 3/25

3:40 pm-10:25 pm

1 stop6h 45m

Memphis

Mon 3/30

2:55 pm-11:15 pm

2 stops8h 20m

$269

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 3/25

5:30 am-3:20 pm

2 stops9h 50m

Memphis

Mon 3/30

2:55 pm-11:15 pm

2 stops8h 20m

$274

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 3/26

6:55 am-11:47 am

1 stop4h 52m

Memphis

Sat 3/28

5:37 pm-10:38 pm

1 stop5h 01m

$277

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 3/28

1:37 pm-6:47 pm

1 stop5h 10m

Memphis

Sat 4/4

6:11 pm-11:46 pm

1 stop5h 35m

$278

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 3/27

4:25 pm-8:26 pm

1 stop4h 01m

Memphis

Tue 3/31

12:07 pm-4:33 pm

1 stop4h 26m

$289

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 3/27

4:25 pm-8:26 pm

1 stop4h 01m

Memphis

Sat 3/28

10:34 am-4:33 pm

1 stop5h 59m

$302

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Memphis from

How to get the cheapest flight ticket from Des Moines to Memphis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Memphis?

United Airlines, Southwest, and American Airlines are the most popular carriers operating from Des Moines to Memphis

When to book flights from Des Moines to Memphis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Memphis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Memphis (DSM to MEM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Memphis

Fastest flight time

5h 27m

Direct flights

None
The fastest flight from Des Moines to Memphis takes 5h 27m
There are no direct flights from Des Moines to Memphis. There are no popular flight routes from Des Moines to Memphis.
Search flight deals

  • How far is Des Moines to Memphis by plane?

    Des Moines and Memphis are 484.7 mi apart from one another. In terms of flight time, this usually takes a little over 5h 27m.

  • When did momondo last update prices for flights from Des Moines Airport to Memphis Airport?

    Prices for flights from Des Moines Airport to Memphis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Memphis Airport?

  • How old do you have to be to fly from Des Moines Airport to Memphis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Memphis Airport.

  • What documentation or ID do you need to fly to Memphis Airport?

    The travel and health documents you'll need for your trip to Memphis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Memphis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Memphis?

Best airlines flying from Des Moines to Memphis

Compare and see reviews for airlines that fly from Des Moines to Memphis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $257Free CancellationRating
7.9
8,180 reviews
Search Delta flights
American AirlinesPriceFrom $263Free CancellationRating
7.2
11,271 reviews
Search American Airlines flights

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Southaven
Tunica
Germantown
West Memphis
Batesville
Forrest City
Cordova
Horn Lake
Marion
Osceola

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Memphis?

Finding the right flight to Memphis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Memphis quick and easy, saving you time and money.

Can I find flights from Des Moines to Memphis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Memphis from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Memphis?

Once all potential Des Moines to Memphis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Memphis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Memphis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Memphis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 3/13
Fri 3/20
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States