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Cheap flights from Des Moines to Memphis from $144

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Memphis departing on 8/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Memphis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
12:10 pm - 7:05 pm
DSM
-
MEM
6h 55m
2 stops
Southwest Logo
5:10 am - 11:30 am
MEM
-
DSM
6h 20m
1 stop
$270Southwest
Sat, Aug 8 - Sat, Aug 15
Southwest Logo
12:10 pm - 7:55 pm
DSM
-
MEM
7h 45m
1 stop
Southwest Logo
5:10 am - 11:30 am
MEM
-
DSM
6h 20m
1 stop
$271Southwest
Sat, Aug 8 - Sat, Aug 15
Delta Logo
11:30 am - 4:47 pm
DSM
-
MEM
5h 17m
1 stop
Delta Logo
6:00 am - 10:43 am
MEM
-
DSM
4h 43m
1 stop
$273Delta
Tue, Jul 28 - Tue, Aug 4
American Airlines Logo
6:33 am - 11:13 am
DSM
-
MEM
4h 40m
1 stop
American Airlines Logo
5:45 pm - 12:35 am
MEM
-
DSM
6h 50m
1 stop
$274American Airlines
Sat, Aug 8 - Sat, Aug 15
Southwest Logo
12:10 pm - 7:05 pm
DSM
-
MEM
6h 55m
2 stops
Southwest Logo
5:10 am - 11:30 am
MEM
-
DSM
6h 20m
1 stop
$278Southwest
Sat, Aug 8 - Sat, Aug 15
Delta Logo
11:30 am - 4:47 pm
DSM
-
MEM
5h 17m
1 stop
Delta Logo
6:00 am - 10:18 am
MEM
-
DSM
4h 18m
1 stop
$281Delta
Tue, Jul 28 - Thu, Aug 6
Delta Logo
5:56 pm - 10:11 pm
DSM
-
MEM
4h 15m
1 stop
Delta Logo
6:00 am - 10:18 am
MEM
-
DSM
4h 18m
1 stop
$289Delta
Thu, Aug 6 - Thu, Aug 13
Delta Logo
6:37 pm - 11:24 pm
DSM
-
MEM
4h 47m
1 stop
Delta Logo
6:00 am - 10:18 am
MEM
-
DSM
4h 18m
1 stop
$310Delta
Thu, Jul 30 - Wed, Aug 5
Southwest Logo
12:10 pm - 7:05 pm
DSM
-
MEM
6h 55m
2 stops
Southwest Logo
8:15 am - 7:25 pm
MEM
-
DSM
11h 10m
2 stops
$316Southwest
Sat, Aug 8 - Sat, Aug 15
Southwest Logo
12:10 pm - 7:05 pm
DSM
-
MEM
6h 55m
2 stops
Southwest Logo
8:15 am - 7:25 pm
MEM
-
DSM
11h 10m
2 stops
$317Southwest
Sat, Aug 8 - Sat, Aug 15

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United Airlines flights from Des Moines to Memphis

Our best United Airlines deals on Des Moines to Memphis flight tickets
United Airlines
Sep 1
DSM9:13 amDes Moines
5h 37m
1 stop
MEM2:50 pmMemphis
Sep 2
MEM7:15 amMemphis
7h 01m
1 stop
DSM2:16 pmDes Moines
$343
United Airlines
Sep 1
DSM9:13 amDes Moines
5h 37m
1 stop
MEM2:50 pmMemphis
Sep 2
MEM6:45 amMemphis
9h 34m
2 stops
DSM4:19 pmDes Moines
$348
United Airlines
Sep 1
DSM6:00 amDes Moines
12h 16m
2 stops
MEM6:16 pmMemphis
Sep 2
MEM6:45 amMemphis
9h 34m
2 stops
DSM4:19 pmDes Moines
$353

Delta flights from Des Moines to Memphis

Our best Delta deals on Des Moines to Memphis flight tickets
Delta
Jul 28
DSM11:30 amDes Moines
5h 17m
1 stop
MEM4:47 pmMemphis
Aug 4
MEM6:00 amMemphis
4h 43m
1 stop
DSM10:43 amDes Moines
$273
Delta
Jul 28
DSM11:30 amDes Moines
5h 17m
1 stop
MEM4:47 pmMemphis
Aug 6
MEM6:00 amMemphis
4h 18m
1 stop
DSM10:18 amDes Moines
$281
Delta
Aug 6
DSM5:56 pmDes Moines
4h 15m
1 stop
MEM10:11 pmMemphis
Aug 13
MEM6:00 amMemphis
4h 18m
1 stop
DSM10:18 amDes Moines
$289

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 26, 2026.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 8/8

12:10 pm-7:05 pm

2 stops6h 55m

Memphis

Sat 8/15

5:10 am-11:30 am

1 stop6h 20m

$270

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 8/8

12:10 pm-7:55 pm

1 stop7h 45m

Memphis

Sat 8/15

5:10 am-11:30 am

1 stop6h 20m

$271

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 7/28

11:30 am-4:47 pm

1 stop5h 17m

Memphis

Tue 8/4

6:00 am-10:43 am

1 stop4h 43m

$273

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 8/8

6:33 am-11:13 am

1 stop4h 40m

Memphis

Sat 8/15

5:45 pm-12:35 am

1 stop6h 50m

$274

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 8/8

12:10 pm-7:05 pm

2 stops6h 55m

Memphis

Sat 8/15

5:10 am-11:30 am

1 stop6h 20m

$278

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 7/28

11:30 am-4:47 pm

1 stop5h 17m

Memphis

Thu 8/6

6:00 am-10:18 am

1 stop4h 18m

$281
Quickest round-trip

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 8/6

5:56 pm-10:11 pm

1 stop4h 15m

Memphis

Thu 8/13

6:00 am-10:18 am

1 stop4h 18m

$289

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 7/30

6:37 pm-11:24 pm

1 stop4h 47m

Memphis

Wed 8/5

6:00 am-10:18 am

1 stop4h 18m

$310

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 8/8

12:10 pm-7:05 pm

2 stops6h 55m

Memphis

Sat 8/15

8:15 am-7:25 pm

2 stops11h 10m

$316

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 8/8

12:10 pm-7:05 pm

2 stops6h 55m

Memphis

Sat 8/15

8:15 am-7:25 pm

2 stops11h 10m

$317

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Memphis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Memphis?

If you aren’t able to travel to Memphis during the month of August, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $277.

When to book flights from Des Moines to Memphis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Memphis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Memphis (DSM to MEM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Memphis

Fastest flight time

4h 31m

Direct flights

None
The fastest flight from Des Moines to Memphis takes 4h 31m
There are no direct flights from Des Moines to Memphis. There are no popular flight routes from Des Moines to Memphis.
Search flight deals

Frequently asked questions about flying from Des Moines to Memphis

  • How far is Des Moines to Memphis by plane?

    Des Moines and Memphis are 484.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 31m.

  • When did momondo last update prices for flights from Des Moines Airport to Memphis Airport?

    Prices for flights from Des Moines Airport to Memphis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Memphis Airport?

  • How old do you have to be to fly from Des Moines Airport to Memphis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Memphis Airport.

  • What documentation or ID do you need to fly to Memphis Airport?

    The travel and health documents you'll need for your trip to Memphis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Memphis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Memphis?

Best airlines flying from Des Moines to Memphis

Compare and see reviews for airlines that fly from Des Moines to Memphis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $263Free CancellationRating
7.8
8,453 reviews
Search Delta flights
American AirlinesPriceFrom $264Free CancellationRating
7.1
11,769 reviews
Search American Airlines flights

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Southaven
Tunica
Germantown
Batesville
West Memphis
Forrest City
Cordova
Horn Lake
Osceola
Marion

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Memphis?

Finding the right flight to Memphis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Memphis quick and easy, saving you time and money.

Can I find flights from Des Moines to Memphis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Memphis from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Memphis?

Once all potential Des Moines to Memphis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Memphis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Memphis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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