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Cheap flights from Des Moines to Memphis from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Memphis departing on 10/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Memphis

Cheap round-trip flights

Logo
2:37 pm - 7:23 pmDSM-MEM
28h 46m1 stop
Logo
7:00 am - 1:47 pmMEM-DSM
30h 47m2 stops
$233
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Wed, Oct 22 - Wed, Oct 29
United Airlines Logo
6:15 am - 1:53 pmDSM-MEM
7h 38m1 stop
United Airlines Logo
3:25 pm - 8:45 pmMEM-DSM
5h 20m1 stop
$237United Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
Southwest Logo
6:20 am - 3:50 pmDSM-MEM
9h 30m2 stops
Southwest Logo
3:20 pm - 9:50 pmMEM-DSM
6h 30m2 stops
$253Southwest
Find Deal
Wed, Oct 22 - Wed, Oct 29
Delta Logo
5:32 pm - 9:56 pmDSM-MEM
4h 24m1 stop
Delta Logo
12:29 pm - 5:44 pmMEM-DSM
5h 15m1 stop
$265Delta
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Thu, Oct 30 - Thu, Nov 6
American Airlines Logo
3:48 pm - 8:59 pmDSM-MEM
5h 11m1 stop
American Airlines Logo
5:27 pm - 11:23 pmMEM-DSM
5h 56m1 stop
$292American Airlines
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Tue, Oct 7 - Thu, Oct 9
American Airlines Logo
6:22 pm - 11:59 pmDSM-MEM
5h 37m1 stop
American Airlines Logo
5:00 am - 10:51 amMEM-DSM
5h 51m1 stop
$309American Airlines
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Fri, Oct 17 - Sun, Oct 19
Allegiant Air Logo
3:17 pm - 6:08 pmDSM-MEM
26h 51m2 stops
Allegiant Air Logo
8:30 pm - 8:05 amMEM-DSM
11h 35m1 stop
$330Allegiant Air
Find Deal
Wed, Oct 1 - Thu, Oct 2
Southwest Logo
6:20 am - 3:50 pmDSM-MEM
9h 30m2 stops
Southwest Logo
10:55 am - 11:30 pmMEM-DSM
12h 35m2 stops
$333Southwest
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Tue, Oct 7 - Thu, Oct 9
Allegiant Air Logo
3:17 pm - 6:08 pmDSM-MEM
26h 51m2 stops
Allegiant Air Logo
4:07 pm - 8:29 amMEM-DSM
16h 22m1 stop
$349Allegiant Air
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Wed, Oct 1 - Fri, Oct 3
Delta Logo
5:44 am - 10:18 amDSM-MEM
4h 34m1 stop
Delta Logo
5:00 pm - 10:37 pmMEM-DSM
5h 37m1 stop
$373Delta
Find Deal
Wed, Oct 1 - Sat, Oct 4

Allegiant Air flights from Des Moines to Memphis

Our best Allegiant Air deals on Des Moines to Memphis flight tickets
Allegiant Air
Oct 1
DSM3:17 pmDes Moines
26h 51m
2 stops
MEM6:08 pmMemphis
Oct 2
MEM8:30 pmMemphis
11h 35m
1 stop
DSM8:05 amDes Moines
$330
Find similar
Allegiant Air
Oct 1
DSM3:17 pmDes Moines
26h 51m
2 stops
MEM6:08 pmMemphis
Oct 3
MEM4:07 pmMemphis
16h 22m
1 stop
DSM8:29 amDes Moines
$349
Find similar

Southwest flights from Des Moines to Memphis

Our best Southwest deals on Des Moines to Memphis flight tickets
Southwest
Oct 22
DSM6:20 amDes Moines
9h 30m
2 stops
MEM3:50 pmMemphis
Oct 29
MEM3:20 pmMemphis
6h 30m
2 stops
DSM9:50 pmDes Moines
$253
Find similar
Southwest
Oct 7
DSM6:20 amDes Moines
9h 30m
2 stops
MEM3:50 pmMemphis
Oct 9
MEM10:55 amMemphis
12h 35m
2 stops
DSM11:30 pmDes Moines
$333
Find similar
Southwest
Sep 30
DSM8:25 amDes Moines
6h 20m
2 stops
MEM2:45 pmMemphis
Oct 1
MEM3:30 pmMemphis
6h 50m
2 stops
DSM10:20 pmDes Moines
$397
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momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 10/22

2:37 pm-7:23 pm

1 stop28h 46m

Memphis

Wed 10/29

7:00 am-1:47 pm

2 stops30h 47m

$233

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 10/22

6:15 am-1:53 pm

1 stop7h 38m

Memphis

Wed 10/29

3:25 pm-8:45 pm

1 stop5h 20m

$237

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 10/22

6:20 am-3:50 pm

2 stops9h 30m

Memphis

Wed 10/29

3:20 pm-9:50 pm

2 stops6h 30m

$253

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 10/30

5:32 pm-9:56 pm

1 stop4h 24m

Memphis

Thu 11/6

12:29 pm-5:44 pm

1 stop5h 15m

$265

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 10/7

3:48 pm-8:59 pm

1 stop5h 11m

Memphis

Thu 10/9

5:27 pm-11:23 pm

1 stop5h 56m

$292

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 10/17

6:22 pm-11:59 pm

1 stop5h 37m

Memphis

Sun 10/19

5:00 am-10:51 am

1 stop5h 51m

$309

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 10/1

3:17 pm-6:08 pm

2 stops26h 51m

Memphis

Thu 10/2

8:30 pm-8:05 am

1 stop11h 35m

$330

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 10/7

6:20 am-3:50 pm

2 stops9h 30m

Memphis

Thu 10/9

10:55 am-11:30 pm

2 stops12h 35m

$333

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 10/1

3:17 pm-6:08 pm

2 stops26h 51m

Memphis

Fri 10/3

4:07 pm-8:29 am

1 stop16h 22m

$349

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 10/1

5:44 am-10:18 am

1 stop4h 34m

Memphis

Sat 10/4

5:00 pm-10:37 pm

1 stop5h 37m

$373

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Memphis from

How to get the cheapest flight ticket from Des Moines to Memphis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Memphis?

According to our data, Saturday is the cheapest day to fly to Memphis from Des Moines. The lowest ticket price found for a Saturday departure recently was $263. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Memphis for around $424.

What is the cheapest time of day to depart on your flight to Memphis?

Our data shows that the cheapest Des Moines to Memphis flights are usually those with departure times in the afternoon. Our users have found flights to Memphis in the afternoon for as low as $322. Try not to purchase tickets in the morning because they tend to be around $366. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Des Moines to Memphis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Memphis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Memphis (DSM to MEM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Memphis

Direct flights

None
There are no direct flights from Des Moines to Memphis. There are no popular flight routes from Des Moines to Memphis.
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  • How far is Des Moines to Memphis by plane?

    Des Moines and Memphis are 484.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 24m.

  • When did momondo last update prices for flights from Des Moines Airport to Memphis Airport?

    Prices for flights from Des Moines Airport to Memphis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Memphis Airport?

  • How old do you have to be to fly from Des Moines Airport to Memphis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Memphis Airport.

  • What documentation or ID do you need to fly to Memphis Airport?

    The travel and health documents you'll need for your trip to Memphis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Memphis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Memphis?

Best airlines flying from Des Moines to Memphis

Compare and see reviews for airlines that fly from Des Moines to Memphis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $252Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $257Free CancellationRating
7.9
7,954 reviews
Search Delta flights

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Southaven
Tunica
Germantown
West Memphis
Forrest City
Horn Lake
Batesville
Cordova
Osceola
Marion

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Memphis?

Finding the right flight to Memphis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Memphis quick and easy, saving you time and money.

Can I find flights from Des Moines to Memphis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Memphis from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Memphis?

Once all potential Des Moines to Memphis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Memphis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Memphis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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