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Cheap flights from Des Moines to Memphis from $107

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Memphis departing on 11/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Memphis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:20 am - 11:29 amDSM-MEM
5h 09m1 stop
Delta Logo
6:00 am - 10:22 amMEM-DSM
4h 22m1 stop
$213Delta
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Sat, Jan 17 - Tue, Jan 20
Delta Logo
6:20 am - 11:29 amDSM-MEM
5h 09m1 stop
Delta Logo
6:00 am - 10:23 amMEM-DSM
4h 23m1 stop
$232Delta
Find Deal
Sat, Jan 17 - Wed, Jan 21
American Airlines Logo
5:01 pm - 11:05 pmDSM-MEM
6h 04m1 stop
American Airlines Logo
8:37 am - 4:24 pmMEM-DSM
7h 47m2 stops
$294American Airlines
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Fri, Jan 16 - Wed, Jan 21
Southwest Logo
6:25 am - 5:40 pmDSM-MEM
11h 15m2 stops
Southwest Logo
2:45 pm - 9:10 pmMEM-DSM
6h 25m2 stops
$306Southwest
Find Deal
Fri, Jan 16 - Wed, Jan 21
Multiple Airlines Logo
12:51 pm - 8:21 pmDSM-MEM
31h 30m1 stop
Multiple Airlines Logo
8:07 pm - 7:03 pmMEM-DSM
22h 56m1 stop
$320Multiple Airlines
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Sun, Nov 30 - Sun, Dec 7
Multiple Airlines Logo
12:51 pm - 8:21 pmDSM-MEM
31h 30m1 stop
Multiple Airlines Logo
8:07 pm - 7:03 pmMEM-DSM
22h 56m1 stop
$326Multiple Airlines
Find Deal
Sun, Nov 30 - Sun, Dec 7
American Airlines Logo
11:42 am - 8:32 pmDSM-MEM
8h 50m2 stops
American Airlines Logo
8:37 am - 4:24 pmMEM-DSM
7h 47m2 stops
$329American Airlines
Find Deal
Fri, Jan 16 - Wed, Jan 21
Southwest Logo
8:00 am - 9:55 pmDSM-MEM
13h 55m2 stops
Southwest Logo
10:40 am - 8:25 pmMEM-DSM
9h 45m1 stop
$340Southwest
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Fri, Nov 7 - Sat, Nov 8
United Airlines Logo
2:57 pm - 9:41 pmDSM-MEM
6h 44m1 stop
United Airlines Logo
3:26 pm - 10:20 pmMEM-DSM
6h 54m1 stop
$447United Airlines
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Thu, Oct 30 - Mon, Nov 3
United Airlines Logo
8:02 am - 3:56 pmDSM-MEM
7h 54m2 stops
United Airlines Logo
3:26 pm - 10:20 pmMEM-DSM
6h 54m1 stop
$452United Airlines
Find Deal
Wed, Oct 29 - Sat, Nov 1

United Airlines flights from Des Moines to Memphis

Our best United Airlines deals on Des Moines to Memphis flight tickets
United Airlines
Oct 30
DSM2:57 pmDes Moines
6h 44m
1 stop
MEM9:41 pmMemphis
Nov 3
MEM3:26 pmMemphis
6h 54m
1 stop
DSM10:20 pmDes Moines
$447
Find similar
United Airlines
Oct 29
DSM8:02 amDes Moines
7h 54m
2 stops
MEM3:56 pmMemphis
Nov 1
MEM3:26 pmMemphis
6h 54m
1 stop
DSM10:20 pmDes Moines
$452
Find similar
United Airlines
Oct 29
DSM8:02 amDes Moines
7h 54m
2 stops
MEM3:56 pmMemphis
Nov 1
MEM6:33 amMemphis
9h 40m
2 stops
DSM4:13 pmDes Moines
$457
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Southwest flights from Des Moines to Memphis

Our best Southwest deals on Des Moines to Memphis flight tickets
Southwest
Jan 16
DSM6:25 amDes Moines
11h 15m
2 stops
MEM5:40 pmMemphis
Jan 21
MEM2:45 pmMemphis
6h 25m
2 stops
DSM9:10 pmDes Moines
$306
Find similar
Southwest
Nov 7
DSM8:00 amDes Moines
13h 55m
2 stops
MEM9:55 pmMemphis
Nov 8
MEM10:40 amMemphis
9h 45m
1 stop
DSM8:25 pmDes Moines
$340
Find similar
Southwest
Nov 7
DSM8:00 amDes Moines
13h 55m
2 stops
MEM9:55 pmMemphis
Nov 8
MEM5:25 amMemphis
15h 00m
2 stops
DSM8:25 pmDes Moines
$364
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momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 1/17

6:20 am-11:29 am

1 stop5h 09m

Memphis

Tue 1/20

6:00 am-10:22 am

1 stop4h 22m

$213

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 1/17

6:20 am-11:29 am

1 stop5h 09m

Memphis

Wed 1/21

6:00 am-10:23 am

1 stop4h 23m

$232

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 1/16

5:01 pm-11:05 pm

1 stop6h 04m

Memphis

Wed 1/21

8:37 am-4:24 pm

2 stops7h 47m

$294

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 1/16

6:25 am-5:40 pm

2 stops11h 15m

Memphis

Wed 1/21

2:45 pm-9:10 pm

2 stops6h 25m

$306

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sun 11/30

12:51 pm-8:21 pm

1 stop31h 30m

Memphis

Sun 12/7

8:07 pm-7:03 pm

1 stop22h 56m

$320

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sun 11/30

12:51 pm-8:21 pm

1 stop31h 30m

Memphis

Sun 12/7

8:07 pm-7:03 pm

1 stop22h 56m

$326

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 1/16

11:42 am-8:32 pm

2 stops8h 50m

Memphis

Wed 1/21

8:37 am-4:24 pm

2 stops7h 47m

$329

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 11/7

8:00 am-9:55 pm

2 stops13h 55m

Memphis

Sat 11/8

10:40 am-8:25 pm

1 stop9h 45m

$340

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 10/30

2:57 pm-9:41 pm

1 stop6h 44m

Memphis

Mon 11/3

3:26 pm-10:20 pm

1 stop6h 54m

$447

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 10/29

8:02 am-3:56 pm

2 stops7h 54m

Memphis

Sat 11/1

3:26 pm-10:20 pm

1 stop6h 54m

$452

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Memphis from

How to get the cheapest flight ticket from Des Moines to Memphis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Memphis?

According to our data, Saturday is the cheapest day to fly to Memphis from Des Moines. The lowest ticket price found for a Saturday departure recently was $263. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Memphis for around $424.

What is the cheapest time of day to depart on your flight to Memphis?

Our data shows that the cheapest Des Moines to Memphis flights are usually those with departure times in the afternoon. Our users have found flights to Memphis in the afternoon for as low as $322. Try not to purchase tickets in the morning because they tend to be around $366. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Des Moines to Memphis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Memphis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Memphis (DSM to MEM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Memphis

Direct flights

None
There are no direct flights from Des Moines to Memphis. There are no popular flight routes from Des Moines to Memphis.
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  • How far is Des Moines to Memphis by plane?

    Des Moines and Memphis are 484.7 mi apart from one another. In terms of flight time, this usually takes a little over 4h 23m.

  • When did momondo last update prices for flights from Des Moines Airport to Memphis Airport?

    Prices for flights from Des Moines Airport to Memphis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Memphis Airport?

  • How old do you have to be to fly from Des Moines Airport to Memphis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Memphis Airport.

  • What documentation or ID do you need to fly to Memphis Airport?

    The travel and health documents you'll need for your trip to Memphis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Memphis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Memphis?

Best airlines flying from Des Moines to Memphis

Compare and see reviews for airlines that fly from Des Moines to Memphis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $252Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights
DeltaPriceFrom $257Free CancellationRating
7.9
7,984 reviews
Search Delta flights

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Southaven
Tunica
Germantown
West Memphis
Forrest City
Batesville
Horn Lake
Cordova
Osceola
Marion

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Memphis?

Finding the right flight to Memphis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Memphis quick and easy, saving you time and money.

Can I find flights from Des Moines to Memphis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Memphis from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Memphis?

Once all potential Des Moines to Memphis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Memphis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Memphis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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