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Cheap flights from Des Moines to Boston from $167

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Boston departing on 8/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Boston

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:07 pm - 10:05 pm
DSM
-
MHT
7h 58m
1 stop
American Airlines Logo
6:01 pm - 12:35 am
MHT
-
DSM
7h 34m
1 stop
$333American Airlines
Wed, Aug 12 - Sat, Aug 15
American Airlines Logo
1:07 pm - 10:05 pm
DSM
-
MHT
7h 58m
1 stop
American Airlines Logo
8:15 am - 12:34 pm
MHT
-
DSM
5h 19m
1 stop
$354American Airlines
Wed, Aug 12 - Thu, Aug 27
Southwest Logo
2:40 pm - 9:10 pm
DSM
-
MHT
5h 30m
1 stop
Southwest Logo
5:40 am - 1:45 pm
MHT
-
DSM
9h 05m
2 stops
$359Southwest
Wed, Aug 12 - Thu, Aug 27
United Airlines Logo
6:00 am - 7:00 pm
DSM
-
MHT
12h 00m
2 stops
United Airlines Logo
2:46 pm - 9:23 pm
MHT
-
DSM
7h 37m
2 stops
$380United Airlines
Wed, Aug 12 - Thu, Aug 27
American Airlines Logo
1:55 pm - 11:52 pm
DSM
-
MHT
8h 57m
2 stops
American Airlines Logo
5:23 pm - 12:35 am
MHT
-
DSM
8h 12m
2 stops
$386American Airlines
Wed, Aug 12 - Sat, Aug 15
American Airlines Logo
8:53 am - 5:47 pm
DSM
-
MHT
7h 54m
1 stop
American Airlines Logo
5:16 pm - 10:52 pm
MHT
-
DSM
6h 36m
1 stop
$390American Airlines
Thu, Jul 23 - Tue, Jul 28
American Airlines Logo
8:53 am - 5:47 pm
DSM
-
MHT
7h 54m
1 stop
American Airlines Logo
5:16 pm - 12:01 am
MHT
-
DSM
7h 45m
2 stops
$395American Airlines
Thu, Jul 23 - Tue, Jul 28
Southwest Logo
3:50 pm - 9:25 pm
DSM
-
MHT
4h 35m
1 stop
Southwest Logo
6:10 pm - 10:50 pm
MHT
-
DSM
5h 40m
1 stop
$401Southwest
Thu, Aug 13 - Sun, Aug 16
United Airlines Logo
6:00 am - 7:00 pm
DSM
-
MHT
12h 00m
2 stops
United Airlines Logo
2:46 pm - 9:23 pm
MHT
-
DSM
7h 37m
2 stops
$409United Airlines
Wed, Aug 12 - Sat, Aug 15
Southwest Logo
3:50 pm - 9:25 pm
DSM
-
MHT
4h 35m
1 stop
Southwest Logo
5:45 am - 7:25 pm
MHT
-
DSM
14h 40m
2 stops
$412Southwest
Thu, Aug 13 - Sat, Aug 15

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Southwest flights from Des Moines to Manchester, New Hampshire

Our best Southwest deals on Des Moines to Manchester, New Hampshire flight tickets
Southwest
Aug 12
DSM2:40 pmDes Moines
5h 30m
1 stop
MHT9:10 pmManchester
Aug 27
MHT5:40 amManchester
9h 05m
2 stops
DSM1:45 pmDes Moines
$359
Southwest
Aug 13
DSM3:50 pmDes Moines
4h 35m
1 stop
MHT9:25 pmManchester
Aug 16
MHT6:10 pmManchester
5h 40m
1 stop
DSM10:50 pmDes Moines
$401
Southwest
Aug 13
DSM3:50 pmDes Moines
4h 35m
1 stop
MHT9:25 pmManchester
Aug 15
MHT5:45 amManchester
14h 40m
2 stops
DSM7:25 pmDes Moines
$412

United Airlines flights from Des Moines to Manchester, New Hampshire

Our best United Airlines deals on Des Moines to Manchester, New Hampshire flight tickets
United Airlines
Aug 12
DSM6:00 amDes Moines
12h 00m
2 stops
MHT7:00 pmManchester
Aug 27
MHT2:46 pmManchester
7h 37m
2 stops
DSM9:23 pmDes Moines
$380
United Airlines
Aug 12
DSM6:00 amDes Moines
12h 00m
2 stops
MHT7:00 pmManchester
Aug 15
MHT2:46 pmManchester
7h 37m
2 stops
DSM9:23 pmDes Moines
$409
United Airlines
Oct 27
DSM9:13 amDes Moines
13h 44m
2 stops
MHT11:57 pmManchester
Oct 31
MHT9:25 amManchester
12h 04m
2 stops
DSM8:29 pmDes Moines
$433

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Manchester, New Hampshire that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Des Moines to Manchester, New Hampshire that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Wed 8/12

1:07 pm-10:05 pm

1 stop7h 58m

Manchester

Sat 8/15

6:01 pm-12:35 am

1 stop7h 34m

$333

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Wed 8/12

1:07 pm-10:05 pm

1 stop7h 58m

Manchester

Thu 8/27

8:15 am-12:34 pm

1 stop5h 19m

$354

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Wed 8/12

2:40 pm-9:10 pm

1 stop5h 30m

Manchester

Thu 8/27

5:40 am-1:45 pm

2 stops9h 05m

$359

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Wed 8/12

6:00 am-7:00 pm

2 stops12h 00m

Manchester

Thu 8/27

2:46 pm-9:23 pm

2 stops7h 37m

$380

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Wed 8/12

1:55 pm-11:52 pm

2 stops8h 57m

Manchester

Sat 8/15

5:23 pm-12:35 am

2 stops8h 12m

$386

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Thu 7/23

8:53 am-5:47 pm

1 stop7h 54m

Manchester

Tue 7/28

5:16 pm-10:52 pm

1 stop6h 36m

$390

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Thu 7/23

8:53 am-5:47 pm

1 stop7h 54m

Manchester

Tue 7/28

5:16 pm-12:01 am

2 stops7h 45m

$395
Quickest round-trip

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Thu 8/13

3:50 pm-9:25 pm

1 stop4h 35m

Manchester

Sun 8/16

6:10 pm-10:50 pm

1 stop5h 40m

$401

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Wed 8/12

6:00 am-7:00 pm

2 stops12h 00m

Manchester

Sat 8/15

2:46 pm-9:23 pm

2 stops7h 37m

$409

Des MoinesManchester

DSM - MHT

DSMMHT

Des Moines

Thu 8/13

3:50 pm-9:25 pm

1 stop4h 35m

Manchester

Sat 8/15

5:45 am-7:25 pm

2 stops14h 40m

$412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Boston from

How to get the cheapest flight ticket from Des Moines to Manchester, New Hampshire

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester, New Hampshire?

If you aren’t able to travel during the month of December, then book flights to Manchester, New Hampshire from Des Moines during November instead. Flights to Manchester, New Hampshire in November, while not as cheap as those in December, still average around $0.

When to book flights from Des Moines to Manchester, New Hampshire

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Manchester, New Hampshire according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Manchester, New Hampshire (DSM to MHT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Manchester, New Hampshire

Fastest flight time

4h 20m

Direct flights

None
The fastest flight from Des Moines to Manchester, New Hampshire takes 4h 20m
There are no direct flights from Des Moines to Manchester, New Hampshire. There are no popular flight routes from Des Moines to Manchester, New Hampshire.
Search flight deals

Frequently asked questions about flying from Des Moines to Manchester, New Hampshire

  • How far is Des Moines to Manchester by plane?

    The straight-line distance from Des Moines to Manchester is 1133.4 mi. 4h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Manchester Airport?

    Prices for flights from Des Moines Airport to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Manchester Airport?

  • How old do you have to be to fly from Des Moines Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents you'll need for your trip to Manchester Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Manchester Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Manchester, New Hampshire?

Best airlines flying from Des Moines to Manchester, New Hampshire

Compare and see reviews for airlines that fly from Des Moines to Manchester, New Hampshire with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $307Free CancellationRating
7.1
11,766 reviews
Search American Airlines flights

Traveling to a place near Boston?

Book flights to Boston if you plan to visit one of these locations
Keene

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Manchester?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Manchester for you.

Can I find flights from Des Moines to Manchester with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Manchester flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Manchester?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to Manchester.

I’m not ready to book a flight from Des Moines to Manchester right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Manchester flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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