What airlines fly to South Carolina?

United Airlines, American Airlines and Southwest are the top three most popular airlines that fly to South Carolina from Denver according to our data. United Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Denver Intl to South Carolina?

Southwest, United Airlines, and Delta are the most popular carriers operating from Denver Intl to South Carolina

How many flights depart from Denver to South Carolina on average per day?

The number of flights available between Denver and South Carolina is 3 per day as of September 2026. The most frequent departure time is 10:00AM, with 62% of daily flights leaving at noon.

How many flights depart from Denver to South Carolina on average per week?

As of September 2026, there are 21 flights per week flying from Denver to South Carolina. The most common day of the week flights depart is Fri, with 19% of flights taking off on this day.

When did momondo last update prices for flights from Denver Intl Airport to South Carolina?

Prices for flights from Denver Intl Airport to South Carolina are updated daily.

How many operators does momondo search for flights from Denver Intl Airport to South Carolina?

The number of operators available for flights from Denver Intl Airport to South Carolina is 6 as of September 2026.

How old do you have to be to fly from Denver Intl Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$117 Cheap Flights from Denver to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to South Carolina

Round-trip

One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

12:45 pm - 9:40 pmDEN Denver Intl-GSP Greenville

6h 55m1 stop Baltimore/Washington

2:50 pm - 9:45 pmGSP Greenville-DEN Denver Intl

8h 55m1 stop Baltimore/Washington

$231Southwest

Fri, Dec 11 - Mon, Dec 14

6:00 am - 12:45 pmDEN Denver Intl-GSP Greenville

4h 45m1 stop Nashville Intl

7:05 pm - 10:15 pmGSP Greenville-DEN Denver Intl

5h 10m1 stop Nashville Intl

$231Southwest

Fri, Jan 8 - Wed, Jan 13

11:59 pm - 9:29 amDEN Denver Intl-MYR Myrtle Beach Intl

7h 30m1 stop Newark

5:00 pm - 11:54 pmMYR Myrtle Beach Intl-DEN Denver Intl

8h 54m1 stop Chicago O'Hare Intl

$277United Airlines

Fri, Oct 16 - Wed, Oct 21

11:59 pm - 9:29 amDEN Denver Intl-MYR Myrtle Beach Intl

7h 30m1 stop Newark

5:00 pm - 11:54 pmMYR Myrtle Beach Intl-DEN Denver Intl

8h 54m1 stop Chicago O'Hare Intl

$277United Airlines

Fri, Oct 16 - Wed, Oct 21

4:07 pm - 11:47 pmDEN Denver Intl-MYR Myrtle Beach Intl

5h 40m1 stop Charlotte Douglas

6:12 am - 10:06 amMYR Myrtle Beach Intl-DEN Denver Intl

5h 54m1 stop Charlotte Douglas

$277American Airlines

Thu, Oct 29 - Tue, Nov 10

11:59 pm - 8:37 amDEN Denver Intl-MYR Myrtle Beach Intl

6h 38m1 stop Charlotte Douglas

4:12 pm - 8:22 pmMYR Myrtle Beach Intl-DEN Denver Intl

6h 10m1 stop Charlotte Douglas

$277American Airlines

Sun, Oct 25 - Fri, Oct 30

10:43 am - 9:32 amDEN Denver Intl-GSP Greenville

20h 49m2 stops Atlanta Hartsfield-Jackson Tampa

8:24 pm - 8:24 amGSP Greenville-DEN Denver Intl

14h 00m1 stop Tampa

$310Multiple Airlines

Wed, Nov 4 - Wed, Nov 11

6:00 am - 3:30 pmDEN Denver Intl-HHH Hilton Head Island

7h 30m1 stop Atlanta Hartsfield-Jackson

12:23 pm - 5:52 pmHHH Hilton Head Island-DEN Denver Intl

7h 29m1 stop Atlanta Hartsfield-Jackson

$311Delta

Tue, Oct 27 - Wed, Nov 4

6:00 am - 3:30 pmDEN Denver Intl-HHH Hilton Head Island

7h 30m1 stop Atlanta Hartsfield-Jackson

12:23 pm - 5:52 pmHHH Hilton Head Island-DEN Denver Intl

7h 29m1 stop Atlanta Hartsfield-Jackson

$311Delta

Sat, Oct 31 - Wed, Nov 4

6:58 pm - 1:24 pmDEN Denver Intl-CHS Charleston

16h 26m1 stop Tampa

1:13 pm - 8:22 amCHS Charleston-DEN Denver Intl

21h 09m2 stops Columbus Atlanta Hartsfield-Jackson

$314Multiple Airlines

Tue, Nov 3 - Tue, Nov 10

Cheap last minute flights

Enter your travel dates to find the best prices.

9:35 am - 3:02 pmDEN Denver Intl-MYR Myrtle Beach Intl

3h 27mnonstop

4:00 pm - 5:58 pmMYR Myrtle Beach Intl-DEN Denver Intl

3h 58mnonstop

$397United Airlines

Sat, Oct 3 - Sat, Oct 10

9:35 am - 3:02 pmDEN Denver Intl-MYR Myrtle Beach Intl

3h 27mnonstop

10:38 am - 4:53 pmMYR Myrtle Beach Intl-DEN Denver Intl

8h 15m1 stop Newark

$407United Airlines

Sat, Oct 3 - Sat, Oct 10

10:29 pm - 10:55 pmDEN Denver Intl-CHS Charleston

22h 26m2 stops San Francisco Richmond Byrd Intl

3:27 pm - 7:52 amCHS Charleston-DEN Denver Intl

18h 25m1 stop Orlando

$432Multiple Airlines

Fri, Oct 2 - Mon, Oct 5

6:14 am - 1:26 pmDEN Denver Intl-MYR Myrtle Beach Intl

5h 12m1 stop Charlotte Douglas

8:13 am - 4:04 pmMYR Myrtle Beach Intl-DEN Denver Intl

9h 51m2 stops Charlotte Douglas Dallas/Fort Worth

$434American Airlines

Tue, Sep 29 - Tue, Oct 6

5:30 am - 1:31 pmDEN Denver Intl-CAE Columbia Metropolitan

6h 01m1 stop Dallas/Fort Worth

5:18 pm - 9:47 pmCAE Columbia Metropolitan-DEN Denver Intl

6h 29m1 stop Dallas/Fort Worth

$436American Airlines

Wed, Sep 30 - Thu, Oct 15

10:28 am - 5:11 pmDEN Denver Intl-CAE Columbia Metropolitan

4h 43m1 stop Atlanta Hartsfield-Jackson

5:59 pm - 11:12 pmCAE Columbia Metropolitan-DEN Denver Intl

7h 13m1 stop Atlanta Hartsfield-Jackson

$436Delta

Wed, Sep 30 - Thu, Oct 15

6:40 am - 10:36 pmDEN Denver Intl-CHS Charleston

13h 56m2 stops Orlando Cincinnati Cinci./N. Kentucky

3:27 pm - 7:52 amCHS Charleston-DEN Denver Intl

18h 25m1 stop Orlando

$455Multiple Airlines

Thu, Oct 1 - Mon, Oct 5

6:00 am - 1:33 pmDEN Denver Intl-MYR Myrtle Beach Intl

5h 33m1 stop Atlanta Hartsfield-Jackson

6:58 pm - 11:12 pmMYR Myrtle Beach Intl-DEN Denver Intl

6h 14m1 stop Atlanta Hartsfield-Jackson

$489Delta

Sun, Oct 4 - Mon, Oct 12

11:25 am - 8:35 pmDEN Denver Intl-GSP Greenville

7h 10m2 stops Louisville Intl Nashville Intl

5:35 pm - 10:10 pmGSP Greenville-DEN Denver Intl

6h 35m1 stop Nashville Intl

$499Southwest

Sat, Oct 3 - Sat, Oct 10

8:20 am - 7:30 pmDEN Denver Intl-MYR Myrtle Beach Intl

9h 10m2 stops Nashville Intl Baltimore/Washington

8:25 am - 4:05 pmMYR Myrtle Beach Intl-DEN Denver Intl

9h 40m2 stops Baltimore/Washington Charleston

$512Southwest

Sat, Oct 3 - Sat, Oct 10

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Southwest flights from Denver to South Carolina

Our best Southwest deals on Denver to South Carolina flight tickets

Southwest

Dec 11

DEN12:45 pmDenver Intl

6h 55m

1 stop

GSP9:40 pmGreenville

Dec 14

GSP2:50 pmGreenville

8h 55m

1 stop

DEN9:45 pmDenver Intl

$231

Southwest

Dec 11

DEN12:35 pmDenver Intl

8h 20m

2 stops

GSP10:55 pmGreenville

Dec 14

GSP2:50 pmGreenville

8h 55m

1 stop

DEN9:45 pmDenver Intl

$236

Southwest

Jan 8

DEN11:15 amDenver Intl

7h 45m

2 stops

GSP9:00 pmGreenville

Jan 13

GSP11:10 amGreenville

8h 30m

2 stops

DEN5:40 pmDenver Intl

$241

United Airlines flights from Denver to South Carolina

Our best United Airlines deals on Denver to South Carolina flight tickets

United Airlines

Oct 16

DEN11:59 pmDenver Intl

7h 30m

1 stop

MYR9:29 amMyrtle Beach Intl

Oct 21

MYR5:00 pmMyrtle Beach Intl

8h 54m

1 stop

DEN11:54 pmDenver Intl

$277

United Airlines

Nov 4

DEN6:00 amDenver Intl

5h 56m

1 stop

CHS1:56 pmCharleston

Nov 9

CHS7:00 pmCharleston

6h 31m

1 stop

DEN11:31 pmDenver Intl

$319

United Airlines

Oct 21

DEN4:20 pmDenver Intl

3h 26m

CHS9:46 pmCharleston

Oct 24

CHS8:26 amCharleston

3h 54m

DEN10:20 amDenver Intl

$327

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Fri 12/11

12:45 pm-9:40 pm

1 stop6h 55m

Greenville

Mon 12/14

2:50 pm-9:45 pm

1 stop8h 55m

$231

Quickest round-trip

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Fri 1/8

6:00 am-12:45 pm

1 stop4h 45m

Greenville

Wed 1/13

7:05 pm-10:15 pm

1 stop5h 10m

$231

DenverMyrtle Beach

DEN Denver Intl - MYR Myrtle Beach Intl

DENMYR

Denver Intl

Fri 10/16

11:59 pm-9:29 am

1 stop7h 30m

Myrtle Beach Intl

Wed 10/21

5:00 pm-11:54 pm

1 stop8h 54m

$277

DenverMyrtle Beach

DEN Denver Intl - MYR Myrtle Beach Intl

DENMYR

Denver Intl

Fri 10/16

11:59 pm-9:29 am

1 stop7h 30m

Myrtle Beach Intl

Wed 10/21

5:00 pm-11:54 pm

1 stop8h 54m

$277

DenverMyrtle Beach

DEN Denver Intl - MYR Myrtle Beach Intl

DENMYR

Denver Intl

Thu 10/29

4:07 pm-11:47 pm

1 stop5h 40m

Myrtle Beach Intl

Tue 11/10

6:12 am-10:06 am

1 stop5h 54m

$277

DenverMyrtle Beach

DEN Denver Intl - MYR Myrtle Beach Intl

DENMYR

Denver Intl

Sun 10/25

11:59 pm-8:37 am

1 stop6h 38m

Myrtle Beach Intl

Fri 10/30

4:12 pm-8:22 pm

1 stop6h 10m

$277

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Wed 11/4

10:43 am-9:32 am

2 stops20h 49m

Greenville

Wed 11/11

8:24 pm-8:24 am

1 stop14h 00m

$310

DenverHilton Head Island

DEN Denver Intl - HHH Hilton Head Island

DENHHH

Denver Intl

Tue 10/27

6:00 am-3:30 pm

1 stop7h 30m

Hilton Head Island

Wed 11/4

12:23 pm-5:52 pm

1 stop7h 29m

$311

DenverHilton Head Island

DEN Denver Intl - HHH Hilton Head Island

DENHHH

Denver Intl

Sat 10/31

6:00 am-3:30 pm

1 stop7h 30m

Hilton Head Island

Wed 11/4

12:23 pm-5:52 pm

1 stop7h 29m

$311

DenverCharleston

DEN Denver Intl - CHS Charleston

DENCHS

Denver Intl

Tue 11/3

6:58 pm-1:24 pm

1 stop16h 26m

Charleston

Tue 11/10

1:13 pm-8:22 am

2 stops21h 09m

$314

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Denver is in April. Flight prices, which tend to average around $392, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of April, then book flights to South Carolina from Denver during January instead. Flights to South Carolina in January, while not as cheap as those in April, still average around $407.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Sunday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $415. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $515.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Denver to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $415. Try not to purchase tickets in the evening because they tend to be around $622. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Denver Intl to South Carolina flight route?

Fly from Denver Intl to Charleston for the best Denver Intl - South Carolina flight prices

How far in advance should I book a flight from Denver to South Carolina?

You are more likely to see cheaper flights to South Carolina from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $430 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Denver for as low as $345 on momondo.

What cabin class options are available on Denver to South Carolina flights?

There are 4 cabin classes available to choose from on Denver to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to South Carolina flights?

You could potentially save up to 12% on your flight if you consider stops on a Denver to South Carolina flight.

Cheap Denver to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South Carolina

Best Price Found	$117
Fastest flight time	3h 02m
Direct flights	Every day
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Denver in the past 72 hours is $117. The best round-trip flight deal from Denver to South Carolina found on momondo in the last 72 hours is $231.

The fastest flight from Denver to South Carolina takes 3h 02m

Direct flights go from Denver to South Carolina every day.

There are 57 airports in South Carolina. From Denver there are direct flights to Greenville (GSP), Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Denver to South Carolina

When did momondo last update prices for flights from Denver Intl Airport to South Carolina?
Prices for flights from Denver Intl Airport to South Carolina are updated daily.
How many operators does momondo search for flights from Denver Intl Airport to South Carolina?
The number of operators available for flights from Denver Intl Airport to South Carolina is 6 as of September 2026.
How old do you have to be to fly from Denver Intl Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Denver to South Carolina?
Based on momondo bookings for flights between Denver and South Carolina, the leading plane model is Boeing 737-800, making up 23.38% of the total bookings. Other popular models include Boeing 737 MAX 8 with 22.43%, Airbus A319 with 13.12%, and Airbus A320-100/200 with 12.55%.

Best airlines flying from Denver to South Carolina

Compare and see reviews for airlines that fly from Denver to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $155	Free Cancellation	Rating 5.6 2,569 reviews	Search Frontier flights
United Airlines	PriceFrom $203	Free Cancellation	Rating 7.4 10,246 reviews	Search United Airlines flights
JetBlue	PriceFrom $208	Free Cancellation	Rating 7.1 3,039 reviews	Search JetBlue flights
Delta	PriceFrom $244	Free Cancellation	Rating 7.8 8,606 reviews	Search Delta flights
American Airlines	PriceFrom $268	Free Cancellation	Rating 7.0 12,097 reviews	Search American Airlines flights
Southwest	PriceFrom $288	Free Cancellation	Rating 8.0 4,202 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Denver with this policy.

How can momondo help me find flights from Denver to South Carolina?

momondo helps you find the best flight between Denver and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Denver are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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Popular cities in South Carolina

Flights to New Yorkfrom $56

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Flights to Las Vegasfrom $44

Flights to Washington, D.C.from $45

Flights to Fort Lauderdalefrom $60

Flights to Bostonfrom $103

Flights to Atlantafrom $38

Flights to Dallasfrom $76

Cheap flights from Denver to South Carolina from $117

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to South Carolina departing on 10/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Southwest flights from Denver to South Carolina

Our best Southwest deals on Denver to South Carolina flight tickets

United Airlines flights from Denver to South Carolina

Our best United Airlines deals on Denver to South Carolina flight tickets

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See travel insights to South Carolina from

How to get the cheapest flight ticket from Denver to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Denver Intl to South Carolina flight route?

How far in advance should I book a flight from Denver to South Carolina?

What cabin class options are available on Denver to South Carolina flights?

Can stopping save me money on Denver to South Carolina flights?

What is the cheapest airline that flies from Denver Intl to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Denver to South Carolina on average per day?

How many flights depart from Denver to South Carolina on average per week?

Cheap Denver to South Carolina flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Frequently asked questions about flying from Denver to South Carolina

Best airlines flying from Denver to South Carolina

Compare and see reviews for airlines that fly from Denver to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

Denver flight routes

According to popular flight searches on momondo this year

South Carolina flight routes

According to popular flight searches on momondo this year

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