What airlines fly to South America?

Copa Airlines, American Airlines and United Airlines are the top three most popular airlines that fly to South America from Denver according to our data. Copa Airlines is the first choice among our users, with 28% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Denver Intl to South America?

United Airlines, Copa Airlines, and Volaris are the most popular carriers operating from Denver Intl to South America

When did momondo last update prices for flights from Denver Intl Airport to South America?

Prices for flights from Denver Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Denver Intl Airport to South America?

As of December 2025, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.

How old do you have to be to fly from Denver Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$131 Cheap Flights from Denver to South America in 2025/26

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Cheap round-trip flights

Enter your travel dates to find the best prices.

5:00 am - 10:35 pm

DEN

BOG

16h 35m1 stop

8:30 am - 10:13 pm

BOG

DEN

14h 43m1 stop

$343United Airlines

Sat, Mar 28 - Mon, Apr 6

5:00 am - 10:35 pm

DEN

BOG

16h 35m1 stop

12:14 am - 2:32 pm

BOG

DEN

15h 18m1 stop

$344United Airlines

Thu, Mar 12 - Tue, Mar 31

12:52 pm - 11:30 pm

DEN

BOG

8h 38m1 stop

8:00 am - 9:11 pm

BOG

DEN

15h 11m2 stops

$348American Airlines

Thu, Jan 29 - Tue, Feb 3

11:59 pm - 10:10 pm

DEN

BOG

20h 11m1 stop

8:00 am - 11:54 pm

BOG

DEN

17h 54m1 stop

$352American Airlines

Wed, Jan 21 - Mon, Feb 2

10:51 pm - 2:09 pm

DEN

UIO

14h 18m1 stop

3:09 am - 6:25 pm

UIO

DEN

16h 16m1 stop

$388Copa Airlines

Wed, Apr 8 - Wed, Apr 15

9:38 pm - 11:01 am

DEN

CTG

11h 23m1 stop

9:42 am - 5:16 pm

CTG

DEN

9h 34m1 stop

$394Copa Airlines

Tue, Feb 24 - Fri, Mar 6

12:59 am - 2:17 pm

DEN

CTG

11h 18m1 stop

3:32 pm - 12:25 am

CTG

DEN

10h 53m1 stop

$406Delta

Sun, Feb 22 - Thu, Feb 26

12:00 pm - 5:17 am

DEN

UIO

15h 17m2 stops

7:00 pm - 12:10 pm

UIO

DEN

19h 10m2 stops

$409LATAM Airlines

Mon, Feb 2 - Mon, Feb 9

12:59 am - 2:17 pm

DEN

CTG

11h 18m1 stop

4:17 pm - 12:25 am

CTG

DEN

34h 08m2 stops

$410Delta

Fri, Feb 20 - Wed, Feb 25

2:42 pm - 5:17 am

DEN

UIO

12h 35m2 stops

11:45 pm - 9:40 am

UIO

DEN

11h 55m1 stop

$422LATAM Airlines

Mon, Feb 2 - Mon, Feb 9

Copa Airlines flights from Denver to South America

Our best Copa Airlines deals on Denver to South America flight tickets

Copa Airlines

Jan 29

DEN9:38 pmDenver Intl

17h 25m

1 stop

BOG5:03 pmBogotá El Dorado

Feb 5

BOG6:10 amBogotá El Dorado

16h 00m

1 stop

DEN8:10 pmDenver Intl

$376

Find similar

Copa Airlines

Apr 8

DEN10:51 pmDenver Intl

14h 18m

1 stop

UIO2:09 pmQuito Mariscal Sucr

Apr 15

UIO3:09 amQuito Mariscal Sucr

16h 16m

1 stop

DEN6:25 pmDenver Intl

$388

Find similar

Copa Airlines

Jan 21

DEN9:38 pmDenver Intl

17h 25m

1 stop

BOG5:03 pmBogotá El Dorado

Feb 2

BOG8:40 amBogotá El Dorado

10h 36m

1 stop

DEN5:16 pmDenver Intl

$389

Find similar

United Airlines flights from Denver to South America

Our best United Airlines deals on Denver to South America flight tickets

United Airlines

Mar 28

DEN5:00 amDenver Intl

16h 35m

1 stop

BOG10:35 pmBogotá El Dorado

Apr 6

BOG8:30 amBogotá El Dorado

14h 43m

1 stop

DEN10:13 pmDenver Intl

$343

Find similar

United Airlines

Mar 12

DEN5:00 amDenver Intl

23h 10m

1 stop

BOG5:10 amBogotá El Dorado

Apr 8

BOG8:30 amBogotá El Dorado

16h 18m

1 stop

DEN11:48 pmDenver Intl

$344

Find similar

United Airlines

Mar 20

DEN5:00 amDenver Intl

16h 35m

1 stop

BOG10:35 pmBogotá El Dorado

Apr 2

BOG8:30 amBogotá El Dorado

25h 13m

1 stop

DEN8:43 amDenver Intl

$350

Find similar

Fly from

Fly to

Route

Depart

Return

Price

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sat 3/28

5:00 am-10:35 pm

1 stop16h 35m

Bogotá El Dorado

Mon 4/6

8:30 am-10:13 pm

1 stop14h 43m

$343

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Thu 3/12

5:00 am-10:35 pm

1 stop16h 35m

Bogotá El Dorado

Tue 3/31

12:14 am-2:32 pm

1 stop15h 18m

$344

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Thu 1/29

12:52 pm-11:30 pm

1 stop8h 38m

Bogotá El Dorado

Tue 2/3

8:00 am-9:11 pm

2 stops15h 11m

$348

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 1/21

11:59 pm-10:10 pm

1 stop20h 11m

Bogotá El Dorado

Mon 2/2

8:00 am-11:54 pm

1 stop17h 54m

$352

DenverQuito

DEN - UIO

DENUIO

Denver Intl

Wed 4/8

10:51 pm-2:09 pm

1 stop14h 18m

Quito Mariscal Sucr

Wed 4/15

3:09 am-6:25 pm

1 stop16h 16m

$388

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Tue 2/24

9:38 pm-11:01 am

1 stop11h 23m

Cartagena Rafael Nunez

Fri 3/6

9:42 am-5:16 pm

1 stop9h 34m

$394

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sun 2/22

12:59 am-2:17 pm

1 stop11h 18m

Cartagena Rafael Nunez

Thu 2/26

3:32 pm-12:25 am

1 stop10h 53m

$406

DenverQuito

DEN - UIO

DENUIO

Denver Intl

Mon 2/2

12:00 pm-5:17 am

2 stops15h 17m

Quito Mariscal Sucr

Mon 2/9

7:00 pm-12:10 pm

2 stops19h 10m

$409

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Fri 2/20

12:59 am-2:17 pm

1 stop11h 18m

Cartagena Rafael Nunez

Wed 2/25

4:17 pm-12:25 am

2 stops34h 08m

$410

DenverQuito

DEN - UIO

DENUIO

Denver Intl

Mon 2/2

2:42 pm-5:17 am

2 stops12h 35m

Quito Mariscal Sucr

Mon 2/9

11:45 pm-9:40 am

1 stop11h 55m

$422

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Denver to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $509. If you aren’t able to travel during the month of November, then book flights to South America from Denver during February instead. Flights to South America in February, while not as cheap as those in November, still average around $545.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Denver to South America is on a Sunday when prices can be found for as low as $551. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to South America for around $655.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Denver to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $549. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $643 on average. Flights to South America from Denver in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $622 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Denver for as low as $558 on momondo.

Can stopping save me money on Denver to South America flights?

You could potentially save up to 13% on your flight if you consider stops on a Denver to South America flight.

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Fastest flight time	8h 18m
Direct flights	None

The fastest flight from Denver to South America takes 8h 18m

There are no direct flights from Denver to South America. There are no popular flight routes from Denver to South America.

Search flight deals

When did momondo last update prices for flights from Denver Intl Airport to South America?
Prices for flights from Denver Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Denver Intl Airport to South America?
As of December 2025, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.
How old do you have to be to fly from Denver Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Airline	Rating	Free Cancellation	Price
Volaris	PriceFrom $207	Free Cancellation	Rating 6.7 1,155 reviews	Search Volaris flights
Copa Airlines	PriceFrom $321	Free Cancellation	Rating 7.6 1,554 reviews	Search Copa Airlines flights
Delta	PriceFrom $323	Free Cancellation	Rating 7.9 8,011 reviews	Search Delta flights
American Airlines	PriceFrom $323	Free Cancellation	Rating 7.2 11,047 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $333	Free Cancellation	Rating 7.5 1,890 reviews	Search LATAM Airlines flights
United Airlines	PriceFrom $339	Free Cancellation	Rating 7.4 9,066 reviews	Search United Airlines flights
Aeromexico	PriceFrom $492	Free Cancellation	Rating 7.4 1,650 reviews	Search Aeromexico flights
Air Canada	PriceFrom $930	Free Cancellation	Rating 7.1 10,500 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

It is quick and easy to find Denver to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Denver to South America with flexible booking policies on momondo?

Flights from Denver to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to South America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South America from Denver.

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

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Find better results for your trip to South America

Popular cities in South America

Flights to Limafrom $227

Flights to Buenos Airesfrom $478

Flights to Bogotáfrom $175

Flights to Sao Paulofrom $314

Flights to Rio de Janeirofrom $455

Flights to Medellínfrom $166

Flights to Santiagofrom $351

Flights to Cartagenafrom $176

Flights to Quitofrom $231

Flights to Cuscofrom $366

Flights to Guayaquilfrom $198

Flights to Califrom $193

Cheap flights from Denver to South America from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to South America departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Denver to South America

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Copa Airlines flights from Denver to South America

Our best Copa Airlines deals on Denver to South America flight tickets

United Airlines flights from Denver to South America

Our best United Airlines deals on Denver to South America flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Denver to South America that are best for you.

How to get the cheapest flight ticket from Denver to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Denver to South America is on a Sunday when prices can be found for as low as $551. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to South America for around $655.

What is the cheapest time of day to depart on your flight to South America?

How far in advance should I book a flight to South America?

Can stopping save me money on Denver to South America flights?

You could potentially save up to 13% on your flight if you consider stops on a Denver to South America flight.

What is the cheapest airline that flies from Denver Intl to South America?

United Airlines, Copa Airlines, and Volaris are the most popular carriers operating from Denver Intl to South America

What airlines fly to South America?

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Fastest flight time

Direct flights

When did momondo last update prices for flights from Denver Intl Airport to South America?

How many operators does momondo search for flights from Denver Intl Airport to South America?

How old do you have to be to fly from Denver Intl Airport to South America?

What documentation or ID do you need to fly to South America?

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

Can I find flights from Denver to South America with flexible booking policies on momondo?

How can momondo help me find flights from Denver to South America?

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo