What airlines fly to South America?

American Airlines, Copa Airlines and United Airlines are the top three most popular airlines that fly to South America from Denver according to our data. American Airlines is the first choice among our users, with 27% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Denver Intl to South America?

United Airlines, Avianca, and Volaris are the most popular carriers operating from Denver Intl to South America

When did momondo last update prices for flights from Denver Intl Airport to South America?

Prices for flights from Denver Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Denver Intl Airport to South America?

As of December 2025, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.

How old do you have to be to fly from Denver Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$123 Cheap Flights from Denver to South America in 2025/26

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One-way

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Cheap round-trip flights

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5:01 am - 10:35 pm

DEN

BOG

15h 34m1 stop

1:30 am - 11:44 am

BOG

DEN

12h 14m1 stop

$359United Airlines

Sun, Jan 18 - Sat, Jan 24

6:59 pm - 12:50 pm

DEN

BOG

15h 51m1 stop

1:45 pm - 8:19 am

BOG

DEN

20h 34m2 stops

$360Multiple Airlines

Sat, Jan 17 - Thu, Jan 29

9:38 pm - 12:52 pm

DEN

UIO

13h 14m1 stop

3:09 am - 5:16 pm

UIO

DEN

16h 07m1 stop

$388Copa Airlines

Tue, Feb 3 - Mon, Feb 9

9:38 pm - 11:01 am

DEN

CTG

11h 23m1 stop

6:25 am - 5:16 pm

CTG

DEN

12h 51m1 stop

$394Copa Airlines

Mon, Feb 9 - Sat, Feb 21

7:20 am - 11:47 pm

DEN

UIO

14h 27m1 stop

7:04 am - 8:53 pm

UIO

DEN

15h 49m2 stops

$405American Airlines

Mon, Jan 26 - Tue, Feb 3

12:30 am - 2:17 pm

DEN

CTG

11h 47m1 stop

3:32 pm - 12:28 am

CTG

DEN

10h 56m1 stop

$406Delta

Thu, Jan 22 - Fri, Feb 6

11:26 pm - 3:30 pm

DEN

CTG

14h 04m1 stop

2:35 pm - 7:20 am

CTG

DEN

18h 45m2 stops

$411American Airlines

Mon, Feb 23 - Sat, Mar 7

4:43 pm - 11:16 pm

DEN

CTG

28h 33m2 stops

3:32 pm - 12:28 am

CTG

DEN

10h 56m1 stop

$412Delta

Sat, Jan 24 - Wed, Feb 4

12:59 am - 8:00 am

DEN

LIM

29h 01m2 stops

12:05 am - 10:18 pm

LIM

DEN

23h 13m2 stops

$474LATAM Airlines

Mon, Feb 23 - Wed, Mar 11

6:23 pm - 8:50 am

DEN

LIM

12h 27m1 stop

12:15 pm - 10:50 pm

LIM

DEN

12h 35m1 stop

$481LATAM Airlines

Wed, Jan 14 - Thu, Jan 29

Delta flights from Denver to South America

Our best Delta deals on Denver to South America flight tickets

Delta

Mar 25

DEN7:05 amDenver Intl

11h 25m

1 stop

BOG7:30 pmBogotá El Dorado

Apr 1

BOG8:40 amBogotá El Dorado

16h 29m

2 stops

DEN12:09 amDenver Intl

$395

Find similar

Delta

Dec 29

DEN6:23 pmDenver Intl

18h 02m

1 stop

BOG2:25 pmBogotá El Dorado

Dec 31

BOG3:55 pmBogotá El Dorado

19h 34m

1 stop

DEN9:29 amDenver Intl

$403

Find similar

Delta

Jan 22

DEN12:30 amDenver Intl

11h 47m

1 stop

CTG2:17 pmCartagena Rafael Nunez

Feb 6

CTG3:32 pmCartagena Rafael Nunez

10h 56m

1 stop

DEN12:28 amDenver Intl

$406

Find similar

United Airlines flights from Denver to South America

Our best United Airlines deals on Denver to South America flight tickets

United Airlines

Jan 18

DEN5:01 amDenver Intl

15h 34m

1 stop

BOG10:35 pmBogotá El Dorado

Jan 24

BOG1:30 amBogotá El Dorado

12h 14m

1 stop

DEN11:44 amDenver Intl

$359

Find similar

United Airlines

Mar 22

DEN9:06 pmDenver Intl

24h 29m

1 stop

BOG10:35 pmBogotá El Dorado

Mar 30

BOG8:30 amBogotá El Dorado

16h 27m

1 stop

DEN11:57 pmDenver Intl

$385

Find similar

United Airlines

Jan 31

DEN5:25 pmDenver Intl

9h 45m

1 stop

BOG5:10 amBogotá El Dorado

Feb 3

BOG1:30 amBogotá El Dorado

14h 54m

1 stop

DEN2:24 pmDenver Intl

$393

Find similar

Fly from

Fly to

Route

Depart

Return

Price

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sun 1/18

5:01 am-10:35 pm

1 stop15h 34m

Bogotá El Dorado

Sat 1/24

1:30 am-11:44 am

1 stop12h 14m

$359

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sat 1/17

6:59 pm-12:50 pm

1 stop15h 51m

Bogotá El Dorado

Thu 1/29

1:45 pm-8:19 am

2 stops20h 34m

$360

DenverQuito

DEN - UIO

DENUIO

Denver Intl

Tue 2/3

9:38 pm-12:52 pm

1 stop13h 14m

Quito Mariscal Sucr

Mon 2/9

3:09 am-5:16 pm

1 stop16h 07m

$388

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Mon 2/9

9:38 pm-11:01 am

1 stop11h 23m

Cartagena Rafael Nunez

Sat 2/21

6:25 am-5:16 pm

1 stop12h 51m

$394

DenverQuito

DEN - UIO

DENUIO

Denver Intl

Mon 1/26

7:20 am-11:47 pm

1 stop14h 27m

Quito Mariscal Sucr

Tue 2/3

7:04 am-8:53 pm

2 stops15h 49m

$405

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Thu 1/22

12:30 am-2:17 pm

1 stop11h 47m

Cartagena Rafael Nunez

Fri 2/6

3:32 pm-12:28 am

1 stop10h 56m

$406

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Mon 2/23

11:26 pm-3:30 pm

1 stop14h 04m

Cartagena Rafael Nunez

Sat 3/7

2:35 pm-7:20 am

2 stops18h 45m

$411

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sat 1/24

4:43 pm-11:16 pm

2 stops28h 33m

Cartagena Rafael Nunez

Wed 2/4

3:32 pm-12:28 am

1 stop10h 56m

$412

DenverLima

DEN - LIM

DENLIM

Denver Intl

Mon 2/23

12:59 am-8:00 am

2 stops29h 01m

Lima J Chavez Intl

Wed 3/11

12:05 am-10:18 pm

2 stops23h 13m

$474

DenverLima

DEN - LIM

DENLIM

Denver Intl

Wed 1/14

6:23 pm-8:50 am

1 stop12h 27m

Lima J Chavez Intl

Thu 1/29

12:15 pm-10:50 pm

1 stop12h 35m

$481

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Denver to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $504. If you aren’t able to travel during the month of November, then book flights to South America from Denver during February instead. Flights to South America in February, while not as cheap as those in November, still average around $545.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Denver to South America is on a Sunday when prices can be found for as low as $551. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to South America for around $655.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Denver to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $549. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $643 on average. Flights to South America from Denver in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $622 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Denver for as low as $545 on momondo.

Can stopping save me money on Denver to South America flights?

You could potentially save up to 13% on your flight if you consider stops on a Denver to South America flight.

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Fastest flight time	8h 19m
Direct flights	None

The fastest flight from Denver to South America takes 8h 19m

There are no direct flights from Denver to South America. There are no popular flight routes from Denver to South America.

Search flight deals

When did momondo last update prices for flights from Denver Intl Airport to South America?
Prices for flights from Denver Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Denver Intl Airport to South America?
As of December 2025, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.
How old do you have to be to fly from Denver Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Airline	Rating	Free Cancellation	Price
Volaris	PriceFrom $168	Free Cancellation	Rating 6.6 1,165 reviews	Search Volaris flights
American Airlines	PriceFrom $323	Free Cancellation	Rating 7.2 11,054 reviews	Search American Airlines flights
Copa Airlines	PriceFrom $331	Free Cancellation	Rating 7.6 1,557 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $333	Free Cancellation	Rating 7.5 1,895 reviews	Search LATAM Airlines flights
Delta	PriceFrom $342	Free Cancellation	Rating 7.9 8,015 reviews	Search Delta flights
United Airlines	PriceFrom $342	Free Cancellation	Rating 7.4 9,111 reviews	Search United Airlines flights
Aeromexico	PriceFrom $492	Free Cancellation	Rating 7.4 1,626 reviews	Search Aeromexico flights
Air Canada	PriceFrom $930	Free Cancellation	Rating 7.1 10,553 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

It is quick and easy to find Denver to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Denver to South America with flexible booking policies on momondo?

Flights from Denver to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to South America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South America from Denver.

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

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Thu 1/22

Thu 1/29

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Find better results for your trip to South America

Popular cities in South America

Flights to Limafrom $255

Flights to Buenos Airesfrom $520

Flights to Sao Paulofrom $403

Flights to Bogotáfrom $163

Flights to Rio de Janeirofrom $473

Flights to Medellínfrom $187

Flights to Santiagofrom $378

Flights to Cartagenafrom $166

Flights to Quitofrom $228

Flights to Cuscofrom $373

Flights to Guayaquilfrom $216

Flights to Califrom $166

Cheap flights from Denver to South America from $123

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to South America departing on 1/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Denver to South America

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Delta flights from Denver to South America

Our best Delta deals on Denver to South America flight tickets

United Airlines flights from Denver to South America

Our best United Airlines deals on Denver to South America flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Denver to South America that are best for you.

How to get the cheapest flight ticket from Denver to South America

What is the cheapest month to fly to South America?

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Denver to South America is on a Sunday when prices can be found for as low as $551. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to South America for around $655.

What is the cheapest time of day to depart on your flight to South America?

How far in advance should I book a flight to South America?

Can stopping save me money on Denver to South America flights?

You could potentially save up to 13% on your flight if you consider stops on a Denver to South America flight.

What is the cheapest airline that flies from Denver Intl to South America?

United Airlines, Avianca, and Volaris are the most popular carriers operating from Denver Intl to South America

What airlines fly to South America?

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Fastest flight time

Direct flights

When did momondo last update prices for flights from Denver Intl Airport to South America?

How many operators does momondo search for flights from Denver Intl Airport to South America?

How old do you have to be to fly from Denver Intl Airport to South America?

What documentation or ID do you need to fly to South America?

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

Can I find flights from Denver to South America with flexible booking policies on momondo?

How can momondo help me find flights from Denver to South America?

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo