What is the cheapest airline that flies from Denver Intl to South America?

Volaris, American Airlines, and Copa Airlines are the most popular carriers operating from Denver Intl to South America

What airlines fly to South America?

Copa Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to South America from Denver according to our data. Copa Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 9 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Denver Intl Airport to South America?

Prices for flights from Denver Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Denver Intl Airport to South America?

As of September 2026, there are 9 operators available to choose from for flights from Denver Intl Airport to South America.

How old do you have to be to fly from Denver Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$191 Cheap Flights from Denver to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:59 pm - 1:35 pmDEN Denver Intl-CTG Cartagena Rafael Nunez

16h 36m2 stops Phoenix Sky Harbor Intl Miami

4:30 pm - 11:37 amCTG Cartagena Rafael Nunez-DEN Denver Intl

21h 07m2 stops Miami Chicago O'Hare Intl

$456American Airlines

Sun, Feb 7 - Fri, Feb 12

6:57 pm - 12:35 pmDEN Denver Intl-CTG Cartagena Rafael Nunez

16h 38m2 stops Phoenix Sky Harbor Intl Miami

1:35 pm - 11:31 amCTG Cartagena Rafael Nunez-DEN Denver Intl

22h 56m2 stops Miami Phoenix Sky Harbor Intl

$456American Airlines

Sun, Oct 25 - Wed, Oct 28

2:50 pm - 11:40 amDEN Denver Intl-MDE Medellín Jose Maria Cordova Intl

18h 50m1 stop New York John F Kennedy Intl

10:40 pm - 1:55 pmMDE Medellín Jose Maria Cordova Intl-DEN Denver Intl

16h 15m1 stop New York John F Kennedy Intl

$495Multiple Airlines

Wed, Feb 24 - Wed, Apr 7

2:50 pm - 11:40 amDEN Denver Intl-MDE Medellín Jose Maria Cordova Intl

18h 50m1 stop New York John F Kennedy Intl

8:10 pm - 1:55 pmMDE Medellín Jose Maria Cordova Intl-DEN Denver Intl

19h 45m1 stop New York John F Kennedy Intl

$495Multiple Airlines

Wed, Feb 24 - Tue, Mar 2

10:43 pm - 9:29 amDEN Denver Intl-BOG Bogotá El Dorado

9h 46m1 stop Panama City Tocumen Intl

9:45 am - 6:11 pmBOG Bogotá El Dorado-DEN Denver Intl

9h 26m1 stop Panama City Tocumen Intl

$498Copa Airlines

Fri, Oct 16 - Sat, Oct 24

9:49 pm - 9:25 amDEN Denver Intl-BOG Bogotá El Dorado

9h 36m1 stop Panama City Tocumen Intl

10:00 am - 5:02 pmBOG Bogotá El Dorado-DEN Denver Intl

9h 02m1 stop Panama City Tocumen Intl

$498Copa Airlines

Sun, Nov 8 - Mon, Nov 16

6:25 pm - 5:55 pmDEN Denver Intl-BOG Bogotá El Dorado

21h 30m2 stops Salt Lake City Miami

10:45 am - 12:23 amBOG Bogotá El Dorado-DEN Denver Intl

15h 38m2 stops Miami Atlanta Hartsfield-Jackson

$503LATAM Airlines

Tue, Jan 19 - Tue, Feb 2

6:25 pm - 5:55 pmDEN Denver Intl-BOG Bogotá El Dorado

21h 30m2 stops Salt Lake City Miami

10:45 am - 10:53 amBOG Bogotá El Dorado-DEN Denver Intl

26h 08m2 stops Miami New York John F Kennedy Intl

$503LATAM Airlines

Tue, Jan 19 - Mon, Jan 25

6:05 am - 11:05 pmDEN Denver Intl-BOG Bogotá El Dorado

15h 00m1 stop Newark

8:15 am - 7:45 pmBOG Bogotá El Dorado-DEN Denver Intl

13h 30m1 stop Houston George Bush Intcntl

$515United Airlines

Thu, Nov 19 - Sat, Dec 12

6:10 pm - 4:54 amDEN Denver Intl-BOG Bogotá El Dorado

9h 44m1 stop Houston George Bush Intcntl

8:15 am - 10:15 pmBOG Bogotá El Dorado-DEN Denver Intl

15h 00m1 stop Houston George Bush Intcntl

$515United Airlines

Mon, Oct 19 - Thu, Oct 29

Cheap last minute flights

Enter your travel dates to find the best prices.

7:15 am - 7:15 pmDEN Denver Intl-BOG Bogotá El Dorado

11h 00m1 stop Atlanta Hartsfield-Jackson

11:00 am - 10:48 amBOG Bogotá El Dorado-DEN Denver Intl

24h 48m2 stops Miami New York John F Kennedy Intl

$521LATAM Airlines

Sun, Sep 13 - Sun, Sep 27

10:07 am - 9:10 pmDEN Denver Intl-MDE Medellín Jose Maria Cordova Intl

10h 03m1 stop Houston George Bush Intcntl

9:45 am - 8:09 pmMDE Medellín Jose Maria Cordova Intl-DEN Denver Intl

11h 24m1 stop Houston George Bush Intcntl

$537United Airlines

Sat, Sep 12 - Sat, Sep 19

10:43 pm - 12:32 amDEN Denver Intl-UIO Quito Mariscal Sucr

24h 49m1 stop Panama City Tocumen Intl

6:30 pm - 6:11 pmUIO Quito Mariscal Sucr-DEN Denver Intl

24h 41m1 stop Panama City Tocumen Intl

$585Copa Airlines

Mon, Sep 14 - Wed, Sep 23

10:43 pm - 12:25 pmDEN Denver Intl-LIM Lima J Chavez Intl

12h 42m1 stop Panama City Tocumen Intl

7:00 am - 6:11 pmLIM Lima J Chavez Intl-DEN Denver Intl

12h 11m1 stop Panama City Tocumen Intl

$591Copa Airlines

Sun, Sep 13 - Sun, Sep 20

6:56 pm - 11:10 pmDEN Denver Intl-LIM Lima J Chavez Intl

27h 14m1 stop Miami

3:00 am - 8:18 amLIM Lima J Chavez Intl-DEN Denver Intl

30h 18m2 stops Punta Cana Miami

$609Multiple Airlines

Tue, Sep 15 - Tue, Oct 20

11:59 pm - 8:30 pmDEN Denver Intl-LIM Lima J Chavez Intl

19h 31m1 stop Miami

6:30 am - 11:03 pmLIM Lima J Chavez Intl-DEN Denver Intl

17h 33m1 stop Miami

$615American Airlines

Sat, Sep 12 - Wed, Sep 16

12:23 pm - 4:10 amDEN Denver Intl-LIM Lima J Chavez Intl

14h 47m1 stop Miami

10:00 pm - 11:22 amLIM Lima J Chavez Intl-DEN Denver Intl

14h 22m1 stop Miami

$615American Airlines

Tue, Sep 15 - Wed, Oct 21

6:00 am - 9:25 pmDEN Denver Intl-LIM Lima J Chavez Intl

14h 25m1 stop Newark

12:55 am - 8:09 pmLIM Lima J Chavez Intl-DEN Denver Intl

20h 14m1 stop Houston George Bush Intcntl

$615United Airlines

Fri, Sep 11 - Fri, Sep 18

12:50 am - 6:59 pmDEN Denver Intl-UIO Quito Mariscal Sucr

17h 09m1 stop Atlanta Hartsfield-Jackson

9:00 am - 8:50 amUIO Quito Mariscal Sucr-DEN Denver Intl

24h 50m2 stops Miami Austin Bergstrom

$622Multiple Airlines

Sun, Sep 13 - Wed, Sep 23

7:15 am - 6:59 pmDEN Denver Intl-UIO Quito Mariscal Sucr

10h 44m1 stop Atlanta Hartsfield-Jackson

9:00 am - 10:48 amUIO Quito Mariscal Sucr-DEN Denver Intl

26h 48m2 stops Miami New York John F Kennedy Intl

$622LATAM Airlines

Mon, Sep 14 - Wed, Sep 23

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JetBlue flights from Denver to South America

Our best JetBlue deals on Denver to South America flight tickets

JetBlue

Nov 19

DEN12:58 amDenver Intl

16h 32m

1 stop

BOG7:30 pmBogotá El Dorado

Dec 4

BOG9:00 amBogotá El Dorado

11h 14m

1 stop

DEN6:14 pmDenver Intl

$565

JetBlue

Nov 19

DEN12:58 amDenver Intl

16h 32m

1 stop

BOG7:30 pmBogotá El Dorado

Dec 4

BOG9:00 amBogotá El Dorado

11h 14m

1 stop

DEN6:14 pmDenver Intl

$575

JetBlue

Dec 16

DEN12:59 amDenver Intl

16h 31m

1 stop

BOG7:30 pmBogotá El Dorado

Jan 5

BOG3:40 pmBogotá El Dorado

10h 43m

1 stop

DEN12:23 amDenver Intl

$580

Iberia flights from Denver to South America

Our best Iberia deals on Denver to South America flight tickets

Iberia

Sep 13

DEN11:59 pmDenver Intl

20h 18m

2 stops

BOG9:17 pmBogotá El Dorado

Sep 27

BOG6:30 amBogotá El Dorado

30h 43m

1 stop

DEN12:13 pmDenver Intl

$642

Iberia

Sep 13

DEN11:59 pmDenver Intl

20h 18m

1 stop

BOG9:17 pmBogotá El Dorado

Sep 27

BOG6:30 amBogotá El Dorado

17h 33m

1 stop

DEN11:03 pmDenver Intl

$647

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverCartagena

DEN Denver Intl - CTG Cartagena Rafael Nunez

DENCTG

Denver Intl

Sun 2/7

6:59 pm-1:35 pm

2 stops16h 36m

Cartagena Rafael Nunez

Fri 2/12

4:30 pm-11:37 am

2 stops21h 07m

$456

DenverCartagena

DEN Denver Intl - CTG Cartagena Rafael Nunez

DENCTG

Denver Intl

Sun 10/25

6:57 pm-12:35 pm

2 stops16h 38m

Cartagena Rafael Nunez

Wed 10/28

1:35 pm-11:31 am

2 stops22h 56m

$456

DenverMedellín

DEN Denver Intl - MDE Medellín Jose Maria Cordova Intl

DENMDE

Denver Intl

Wed 2/24

2:50 pm-11:40 am

1 stop18h 50m

Medellín Jose Maria Cordova Intl

Wed 4/7

10:40 pm-1:55 pm

1 stop16h 15m

$495

DenverMedellín

DEN Denver Intl - MDE Medellín Jose Maria Cordova Intl

DENMDE

Denver Intl

Wed 2/24

2:50 pm-11:40 am

1 stop18h 50m

Medellín Jose Maria Cordova Intl

Tue 3/2

8:10 pm-1:55 pm

1 stop19h 45m

$495

DenverBogotá

DEN Denver Intl - BOG Bogotá El Dorado

DENBOG

Denver Intl

Fri 10/16

10:43 pm-9:29 am

1 stop9h 46m

Bogotá El Dorado

Sat 10/24

9:45 am-6:11 pm

1 stop9h 26m

$498

Quickest round-trip

DenverBogotá

DEN Denver Intl - BOG Bogotá El Dorado

DENBOG

Denver Intl

Sun 11/8

9:49 pm-9:25 am

1 stop9h 36m

Bogotá El Dorado

Mon 11/16

10:00 am-5:02 pm

1 stop9h 02m

$498

DenverBogotá

DEN Denver Intl - BOG Bogotá El Dorado

DENBOG

Denver Intl

Tue 1/19

6:25 pm-5:55 pm

2 stops21h 30m

Bogotá El Dorado

Tue 2/2

10:45 am-12:23 am

2 stops15h 38m

$503

DenverBogotá

DEN Denver Intl - BOG Bogotá El Dorado

DENBOG

Denver Intl

Tue 1/19

6:25 pm-5:55 pm

2 stops21h 30m

Bogotá El Dorado

Mon 1/25

10:45 am-10:53 am

2 stops26h 08m

$503

DenverBogotá

DEN Denver Intl - BOG Bogotá El Dorado

DENBOG

Denver Intl

Thu 11/19

6:05 am-11:05 pm

1 stop15h 00m

Bogotá El Dorado

Sat 12/12

8:15 am-7:45 pm

1 stop13h 30m

$515

DenverBogotá

DEN Denver Intl - BOG Bogotá El Dorado

DENBOG

Denver Intl

Mon 10/19

6:10 pm-4:54 am

1 stop9h 44m

Bogotá El Dorado

Thu 10/29

8:15 am-10:15 pm

1 stop15h 00m

$515

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, April is the cheapest month to fly from Denver to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $650. If you aren’t able to travel during the month of April, then book flights to South America from Denver during January instead. Flights to South America in January, while not as cheap as those in April, still average around $676.

How far in advance should I book a flight from Denver to South America?

You are more likely to see cheaper flights to South America from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $650 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Denver for as low as $594 on momondo.

Can stopping save me money on Denver to South America flights?

You could potentially save up to 20% on your flight if you consider stops on a Denver to South America flight.

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Best Price Found	$191
Fastest flight time	8h 05m
Direct flights	None

The best one-way flight to South America from Denver in the past 72 hours is $191. The best round-trip flight deal from Denver to South America found on momondo in the last 72 hours is $456.

The fastest flight from Denver to South America takes 8h 05m

There are no direct flights from Denver to South America. There are no popular flight routes from Denver to South America.

Search flight deals

Frequently asked questions about flying from Denver to South America

When did momondo last update prices for flights from Denver Intl Airport to South America?
Prices for flights from Denver Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Denver Intl Airport to South America?
As of September 2026, there are 9 operators available to choose from for flights from Denver Intl Airport to South America.
How old do you have to be to fly from Denver Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Airline	Rating	Free Cancellation	Price
Volaris	PriceFrom $157	Free Cancellation	Rating 6.6 1,142 reviews	Search Volaris flights
United Airlines	PriceFrom $276	Free Cancellation	Rating 7.4 10,194 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $302	Free Cancellation	Rating 7.6 1,546 reviews	Search Copa Airlines flights
Delta	PriceFrom $322	Free Cancellation	Rating 7.8 8,553 reviews	Search Delta flights
American Airlines	PriceFrom $342	Free Cancellation	Rating 7.1 12,047 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $379	Free Cancellation	Rating 7.4 1,987 reviews	Search LATAM Airlines flights
Avianca	PriceFrom $433	Free Cancellation	Rating 6.5 2,553 reviews	Search Avianca flights
Air Canada	PriceFrom $468	Free Cancellation	Rating 7.1 11,608 reviews	Search Air Canada flights
GOL	PriceFrom $613	Free Cancellation	Rating 7.3 1,296 reviews	Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

It is quick and easy to find Denver to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Denver to South America with flexible booking policies on momondo?

Flights from Denver to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to South America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South America from Denver.

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.