What is the cheapest airline that flies from Denver Intl to South America?

United Airlines, Copa Airlines, and Delta are the most popular carriers operating from Denver Intl to South America

What airlines fly to South America?

Copa Airlines, American Airlines and United Airlines are the top three most popular airlines that fly to South America from Denver according to our data. Copa Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Denver Intl Airport to South America?

Prices for flights from Denver Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Denver Intl Airport to South America?

As of December 2025, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.

How old do you have to be to fly from Denver Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$123 Cheap Flights from Denver to South America in 2025/26

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Find the cheapest flights from Denver to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:59 pm - 6:55 pm

DEN

MDE

16h 56m2 stops

11:50 pm - 9:11 am

MDE

DEN

11h 21m1 stop

$361Multiple Airlines

Tue, Feb 24 - Mon, Mar 2

10:51 pm - 5:07 pm

DEN

BOG

17h 16m1 stop

8:35 am - 6:25 pm

BOG

DEN

10h 50m1 stop

$361Copa Airlines

Mon, May 18 - Sun, May 24

5:25 pm - 4:54 am

DEN

BOG

10h 29m1 stop

8:30 am - 8:13 pm

BOG

DEN

12h 43m1 stop

$376United Airlines

Sat, Mar 28 - Sat, Apr 4

8:44 am - 11:30 pm

DEN

BOG

12h 46m1 stop

8:00 am - 10:10 pm

BOG

DEN

16h 10m1 stop

$393American Airlines

Wed, Jan 21 - Sat, Jan 31

7:05 am - 8:20 pm

DEN

BOG

11h 15m2 stops

9:00 am - 10:50 pm

BOG

DEN

15h 50m1 stop

$396LATAM Airlines

Wed, Jan 21 - Sun, Feb 1

11:59 pm - 1:34 pm

DEN

CTG

11h 35m2 stops

8:00 am - 8:14 pm

CTG

DEN

13h 14m2 stops

$398American Airlines

Sat, Feb 28 - Wed, Mar 11

8:33 pm - 11:00 pm

DEN

CTG

24h 27m2 stops

9:42 am - 11:45 am

CTG

DEN

27h 03m2 stops

$399United Airlines

Sat, Feb 28 - Wed, Mar 11

12:59 am - 2:17 pm

DEN

CTG

11h 18m1 stop

3:32 pm - 12:23 am

CTG

DEN

10h 51m1 stop

$406Delta

Sun, Mar 1 - Sat, Mar 7

7:20 am - 12:01 pm

DEN

CTG

26h 41m2 stops

3:32 pm - 12:23 am

CTG

DEN

10h 51m1 stop

$412Delta

Fri, Feb 27 - Wed, Mar 4

2:42 pm - 5:00 am

DEN

LIM

12h 18m1 stop

8:00 am - 10:50 pm

LIM

DEN

16h 50m2 stops

$477LATAM Airlines

Fri, Jan 23 - Wed, Jan 28

Copa Airlines flights from Denver to South America

Our best Copa Airlines deals on Denver to South America flight tickets

Copa Airlines

May 18

DEN10:51 pmDenver Intl

17h 16m

1 stop

BOG5:07 pmBogotá El Dorado

May 24

BOG8:35 amBogotá El Dorado

10h 50m

1 stop

DEN6:25 pmDenver Intl

$361

Find similar

Copa Airlines

Feb 14

DEN9:38 pmDenver Intl

13h 51m

1 stop

BOG1:29 pmBogotá El Dorado

Feb 24

BOG7:00 amBogotá El Dorado

12h 16m

1 stop

DEN5:16 pmDenver Intl

$387

Find similar

Copa Airlines

Feb 14

DEN9:38 pmDenver Intl

13h 14m

1 stop

UIO12:52 pmQuito Mariscal Sucr

Feb 23

UIO3:09 amQuito Mariscal Sucr

16h 07m

1 stop

DEN5:16 pmDenver Intl

$388

Find similar

United Airlines flights from Denver to South America

Our best United Airlines deals on Denver to South America flight tickets

United Airlines

Mar 28

DEN5:25 pmDenver Intl

10h 29m

1 stop

BOG4:54 amBogotá El Dorado

Apr 4

BOG8:30 amBogotá El Dorado

12h 43m

1 stop

DEN8:13 pmDenver Intl

$376

Find similar

United Airlines

Feb 28

DEN8:33 pmDenver Intl

24h 27m

2 stops

CTG11:00 pmCartagena Rafael Nunez

Mar 11

CTG9:42 amCartagena Rafael Nunez

27h 03m

2 stops

DEN11:45 amDenver Intl

$399

Find similar

United Airlines

Jan 21

DEN8:32 pmDenver Intl

24h 03m

1 stop

BOG10:35 pmBogotá El Dorado

Jan 25

BOG8:15 amBogotá El Dorado

17h 26m

1 stop

DEN11:41 pmDenver Intl

$400

Find similar

Fly from

Fly to

Route

Depart

Return

Price

DenverMedellín

DEN - MDE

DENMDE

Denver Intl

Tue 2/24

11:59 pm-6:55 pm

2 stops16h 56m

Medellín Jose Maria Cordova Intl

Mon 3/2

11:50 pm-9:11 am

1 stop11h 21m

$361

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Mon 5/18

10:51 pm-5:07 pm

1 stop17h 16m

Bogotá El Dorado

Sun 5/24

8:35 am-6:25 pm

1 stop10h 50m

$361

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sat 3/28

5:25 pm-4:54 am

1 stop10h 29m

Bogotá El Dorado

Sat 4/4

8:30 am-8:13 pm

1 stop12h 43m

$376

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 1/21

8:44 am-11:30 pm

1 stop12h 46m

Bogotá El Dorado

Sat 1/31

8:00 am-10:10 pm

1 stop16h 10m

$393

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 1/21

7:05 am-8:20 pm

2 stops11h 15m

Bogotá El Dorado

Sun 2/1

9:00 am-10:50 pm

1 stop15h 50m

$396

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sat 2/28

11:59 pm-1:34 pm

2 stops11h 35m

Cartagena Rafael Nunez

Wed 3/11

8:00 am-8:14 pm

2 stops13h 14m

$398

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sat 2/28

8:33 pm-11:00 pm

2 stops24h 27m

Cartagena Rafael Nunez

Wed 3/11

9:42 am-11:45 am

2 stops27h 03m

$399

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sun 3/1

12:59 am-2:17 pm

1 stop11h 18m

Cartagena Rafael Nunez

Sat 3/7

3:32 pm-12:23 am

1 stop10h 51m

$406

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Fri 2/27

7:20 am-12:01 pm

2 stops26h 41m

Cartagena Rafael Nunez

Wed 3/4

3:32 pm-12:23 am

1 stop10h 51m

$412

DenverLima

DEN - LIM

DENLIM

Denver Intl

Fri 1/23

2:42 pm-5:00 am

1 stop12h 18m

Lima J Chavez Intl

Wed 1/28

8:00 am-10:50 pm

2 stops16h 50m

$477

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Denver to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $504. If you aren’t able to travel during the month of November, then book flights to South America from Denver during February instead. Flights to South America in February, while not as cheap as those in November, still average around $545.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $621 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Denver for as low as $545 on momondo.

Can stopping save me money on Denver to South America flights?

You could potentially save up to 4% on your flight if you consider stops on a Denver to South America flight.

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Fastest flight time	8h 18m
Direct flights	None

The fastest flight from Denver to South America takes 8h 18m

There are no direct flights from Denver to South America. There are no popular flight routes from Denver to South America.

Search flight deals

When did momondo last update prices for flights from Denver Intl Airport to South America?
Prices for flights from Denver Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Denver Intl Airport to South America?
As of December 2025, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.
How old do you have to be to fly from Denver Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Airline	Rating	Free Cancellation	Price
Volaris	PriceFrom $168	Free Cancellation	Rating 6.6 1,166 reviews	Search Volaris flights
Delta	PriceFrom $323	Free Cancellation	Rating 7.9 8,014 reviews	Search Delta flights
American Airlines	PriceFrom $324	Free Cancellation	Rating 7.2 11,072 reviews	Search American Airlines flights
Copa Airlines	PriceFrom $331	Free Cancellation	Rating 7.6 1,562 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $331	Free Cancellation	Rating 7.5 1,895 reviews	Search LATAM Airlines flights
United Airlines	PriceFrom $342	Free Cancellation	Rating 7.4 9,120 reviews	Search United Airlines flights
Aeromexico	PriceFrom $492	Free Cancellation	Rating 7.4 1,621 reviews	Search Aeromexico flights
Air Canada	PriceFrom $930	Free Cancellation	Rating 7.1 10,563 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

It is quick and easy to find Denver to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Denver to South America with flexible booking policies on momondo?

Flights from Denver to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to South America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South America from Denver.

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.