What is the cheapest airline that flies from Denver Intl to South America?

Delta, Copa Airlines, and United Airlines are the most popular carriers operating from Denver Intl to South America

What airlines fly to South America?

Copa Airlines, American Airlines and United Airlines are the top three most popular airlines that fly to South America from Denver according to our data. Copa Airlines is the first choice among our users, with 28% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Denver Intl Airport to South America?

Prices for flights from Denver Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Denver Intl Airport to South America?

As of November 2025, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.

How old do you have to be to fly from Denver Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$135 Cheap Flights from Denver to South America in 2025/26

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One-way

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Cheap round-trip flights

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6:59 pm - 1:55 pmDEN-MDE

16h 56m1 stop

2:50 pm - 8:30 amMDE-DEN

19h 40m1 stop

$334Multiple Airlines

Find Deal

Sat, Jan 17 - Sat, Jan 24

3:14 pm - 1:30 pmDEN-CTG

20h 16m2 stops

8:00 am - 11:05 pmCTG-DEN

17h 05m2 stops

$341American Airlines

Find Deal

Mon, Dec 8 - Fri, Dec 12

5:00 am - 10:35 pmDEN-BOG

16h 35m1 stop

8:30 am - 8:13 pmBOG-DEN

12h 43m1 stop

$343United Airlines

Find Deal

Sun, Mar 22 - Sat, Apr 4

7:20 pm - 10:35 pmDEN-BOG

25h 15m1 stop

8:15 am - 11:41 pmBOG-DEN

17h 26m1 stop

$350United Airlines

Find Deal

Sat, Jan 31 - Sun, Feb 8

12:55 am - 4:45 pmDEN-BOG

14h 50m2 stops

2:55 pm - 12:09 amBOG-DEN

10h 14m1 stop

$353Delta

Find Deal

Mon, Mar 23 - Mon, Mar 30

12:55 am - 4:45 pmDEN-BOG

14h 50m2 stops

2:55 pm - 12:09 amBOG-DEN

10h 14m1 stop

$354Delta

Find Deal

Mon, Mar 23 - Wed, Apr 1

10:38 pm - 12:52 pmDEN-UIO

13h 14m1 stop

8:32 am - 6:16 pmUIO-DEN

10h 44m1 stop

$388Copa Airlines

Find Deal

Wed, Apr 29 - Wed, May 6

10:38 pm - 8:41 amDEN-CTG

9h 03m1 stop

6:24 am - 6:16 pmCTG-DEN

12h 52m1 stop

$394Copa Airlines

Find Deal

Sat, May 16 - Fri, May 22

12:42 pm - 5:00 amDEN-LIM

14h 18m1 stop

12:15 pm - 10:50 pmLIM-DEN

12h 35m1 stop

$454LATAM Airlines

Find Deal

Wed, Dec 31 - Tue, Feb 3

12:00 pm - 5:00 amDEN-LIM

15h 00m1 stop

8:25 am - 12:09 amLIM-DEN

16h 44m2 stops

$468LATAM Airlines

Find Deal

Tue, Mar 3 - Tue, Mar 10

LATAM Airlines flights from Denver to South America

Our best LATAM Airlines deals on Denver to South America flight tickets

LATAM Airlines

Mar 26

DEN6:40 amDenver Intl

12h 40m

2 stops

BOG8:20 pmBogotá El Dorado

Apr 2

BOG2:55 pmBogotá El Dorado

10h 14m

1 stop

DEN12:09 amDenver Intl

$365

Find similar

LATAM Airlines

Feb 1

DEN12:30 amDenver Intl

19h 45m

2 stops

BOG10:15 pmBogotá El Dorado

Feb 16

BOG3:55 pmBogotá El Dorado

10h 30m

1 stop

DEN12:25 amDenver Intl

$370

Find similar

LATAM Airlines

Feb 3

DEN7:05 amDenver Intl

10h 25m

1 stop

BOG7:30 pmBogotá El Dorado

Feb 3

BOG1:35 amBogotá El Dorado

23h 15m

2 stops

DEN10:50 pmDenver Intl

$372

Find similar

Copa Airlines flights from Denver to South America

Our best Copa Airlines deals on Denver to South America flight tickets

Copa Airlines

Jan 19

DEN9:38 pmDenver Intl

10h 32m

1 stop

BOG10:10 amBogotá El Dorado

Jan 29

BOG7:00 amBogotá El Dorado

12h 16m

1 stop

DEN5:16 pmDenver Intl

$361

Find similar

Copa Airlines

Jan 19

DEN9:38 pmDenver Intl

9h 47m

1 stop

BOG9:25 amBogotá El Dorado

Jan 29

BOG7:00 amBogotá El Dorado

12h 16m

1 stop

DEN5:16 pmDenver Intl

$381

Find similar

Copa Airlines

Jan 14

DEN9:38 pmDenver Intl

9h 47m

1 stop

BOG9:25 amBogotá El Dorado

Jan 20

BOG6:08 pmBogotá El Dorado

25h 08m

1 stop

DEN5:16 pmDenver Intl

$384

Find similar

Fly from

Fly to

Route

Depart

Return

Price

DenverMedellín

DEN - MDE

DENMDE

Denver Intl

Sat 1/17

6:59 pm-1:55 pm

1 stop16h 56m

Medellín Jose Maria Cordova Intl

Sat 1/24

2:50 pm-8:30 am

1 stop19h 40m

$334

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Mon 12/8

3:14 pm-1:30 pm

2 stops20h 16m

Cartagena Rafael Nunez

Fri 12/12

8:00 am-11:05 pm

2 stops17h 05m

$341

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sun 3/22

5:00 am-10:35 pm

1 stop16h 35m

Bogotá El Dorado

Sat 4/4

8:30 am-8:13 pm

1 stop12h 43m

$343

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sat 1/31

7:20 pm-10:35 pm

1 stop25h 15m

Bogotá El Dorado

Sun 2/8

8:15 am-11:41 pm

1 stop17h 26m

$350

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Mon 3/23

12:55 am-4:45 pm

2 stops14h 50m

Bogotá El Dorado

Mon 3/30

2:55 pm-12:09 am

1 stop10h 14m

$353

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Mon 3/23

12:55 am-4:45 pm

2 stops14h 50m

Bogotá El Dorado

Wed 4/1

2:55 pm-12:09 am

1 stop10h 14m

$354

DenverQuito

DEN - UIO

DENUIO

Denver Intl

Wed 4/29

10:38 pm-12:52 pm

1 stop13h 14m

Quito Mariscal Sucr

Wed 5/6

8:32 am-6:16 pm

1 stop10h 44m

$388

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sat 5/16

10:38 pm-8:41 am

1 stop9h 03m

Cartagena Rafael Nunez

Fri 5/22

6:24 am-6:16 pm

1 stop12h 52m

$394

DenverLima

DEN - LIM

DENLIM

Denver Intl

Wed 12/31

12:42 pm-5:00 am

1 stop14h 18m

Lima J Chavez Intl

Tue 2/3

12:15 pm-10:50 pm

1 stop12h 35m

$454

DenverLima

DEN - LIM

DENLIM

Denver Intl

Tue 3/3

12:00 pm-5:00 am

1 stop15h 00m

Lima J Chavez Intl

Tue 3/10

8:25 am-12:09 am

2 stops16h 44m

$468

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Denver to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $508. If you aren’t able to travel during the month of November, then book flights to South America from Denver during February instead. Flights to South America in February, while not as cheap as those in November, still average around $545.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Denver to South America is on a Sunday when prices can be found for as low as $551. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to South America for around $655.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Denver to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $549. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $643 on average. Flights to South America from Denver in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $624 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Denver for as low as $558 on momondo.

Can stopping save me money on Denver to South America flights?

You could potentially save up to 13% on your flight if you consider stops on a Denver to South America flight.

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Fastest flight time	8h 19m
Direct flights	None

The fastest flight from Denver to South America takes 8h 19m

There are no direct flights from Denver to South America. There are no popular flight routes from Denver to South America.

Search flight deals

When did momondo last update prices for flights from Denver Intl Airport to South America?
Prices for flights from Denver Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Denver Intl Airport to South America?
As of November 2025, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.
How old do you have to be to fly from Denver Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Airline	Rating	Free Cancellation	Price
Volaris	PriceFrom $207	Free Cancellation	Rating 6.7 1,153 reviews	Search Volaris flights
Copa Airlines	PriceFrom $321	Free Cancellation	Rating 7.6 1,569 reviews	Search Copa Airlines flights
Delta	PriceFrom $323	Free Cancellation	Rating 7.9 7,998 reviews	Search Delta flights
American Airlines	PriceFrom $323	Free Cancellation	Rating 7.2 11,038 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $333	Free Cancellation	Rating 7.5 1,886 reviews	Search LATAM Airlines flights
United Airlines	PriceFrom $338	Free Cancellation	Rating 7.4 9,046 reviews	Search United Airlines flights
Aeromexico	PriceFrom $492	Free Cancellation	Rating 7.4 1,658 reviews	Search Aeromexico flights
Air Canada	PriceFrom $930	Free Cancellation	Rating 7.1 10,476 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

It is quick and easy to find Denver to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Denver to South America with flexible booking policies on momondo?

Flights from Denver to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to South America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South America from Denver.

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

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Fri 12/26

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Find better results for your trip to South America

Popular cities in South America

Flights to Limafrom $290

Flights to Buenos Airesfrom $538

Flights to Bogotáfrom $200

Flights to Sao Paulofrom $379

Flights to Rio de Janeirofrom $451

Flights to Medellínfrom $165

Flights to Santiagofrom $375

Flights to Cartagenafrom $169

Flights to Quitofrom $324

Flights to Cuscofrom $441

Flights to Guayaquilfrom $212

Flights to Califrom $202

Cheap flights from Denver to South America from $135

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to South America departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Denver to South America

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

LATAM Airlines flights from Denver to South America

Our best LATAM Airlines deals on Denver to South America flight tickets

Copa Airlines flights from Denver to South America

Our best Copa Airlines deals on Denver to South America flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Denver to South America that are best for you.

How to get the cheapest flight ticket from Denver to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Denver to South America is on a Sunday when prices can be found for as low as $551. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to South America for around $655.

What is the cheapest time of day to depart on your flight to South America?

How far in advance should I book a flight to South America?

Can stopping save me money on Denver to South America flights?

You could potentially save up to 13% on your flight if you consider stops on a Denver to South America flight.

What is the cheapest airline that flies from Denver Intl to South America?

Delta, Copa Airlines, and United Airlines are the most popular carriers operating from Denver Intl to South America

What airlines fly to South America?

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Fastest flight time

Direct flights

When did momondo last update prices for flights from Denver Intl Airport to South America?

How many operators does momondo search for flights from Denver Intl Airport to South America?

How old do you have to be to fly from Denver Intl Airport to South America?

What documentation or ID do you need to fly to South America?

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

Can I find flights from Denver to South America with flexible booking policies on momondo?

How can momondo help me find flights from Denver to South America?

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo