What airlines fly to South America?

Copa Airlines, American Airlines and United Airlines are the top three most popular airlines that fly to South America from Denver according to our data. Copa Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Denver Intl to South America?

JetBlue, Copa Airlines, and American Airlines are the most popular carriers operating from Denver Intl to South America

When did momondo last update prices for flights from Denver Intl Airport to South America?

Prices for flights from Denver Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Denver Intl Airport to South America?

As of January 2026, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.

How old do you have to be to fly from Denver Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$127 Cheap Flights from Denver to South America in 2026

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Find the cheapest flights from Denver to South America

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

9:38 pm - 11:01 am

DEN

CTG

11h 23m

1 stop

6:25 am - 5:16 pm

CTG

DEN

12h 51m

1 stop

$325Copa Airlines

Mon, Feb 23 - Sat, Mar 7

11:59 pm - 3:30 pm

DEN

CTG

13h 31m

2 stops

1:28 pm - 11:59 pm

CTG

DEN

11h 31m

1 stop

$330American Airlines

Sat, Feb 28 - Wed, Mar 11

2:14 pm - 12:09 pm

DEN

CTG

20h 55m

2 stops

1:25 pm - 9:38 am

CTG

DEN

21h 13m

2 stops

$342American Airlines

Mon, Apr 6 - Fri, Apr 17

9:48 pm - 8:06 am

DEN

CTG

8h 18m

1 stop

9:22 am - 6:16 pm

CTG

DEN

9h 54m

1 stop

$345Copa Airlines

Thu, Mar 5 - Thu, Mar 12

8:23 pm - 7:20 pm

DEN

BOG

21h 57m

1 stop

8:30 am - 2:26 pm

BOG

DEN

30h 56m

1 stop

$348United Airlines

Sun, Apr 26 - Fri, May 1

7:45 am - 7:20 pm

DEN

BOG

10h 35m

1 stop

12:14 am - 8:38 am

BOG

DEN

9h 24m

1 stop

$355United Airlines

Tue, Apr 7 - Fri, Apr 24

2:45 pm - 5:00 am

DEN

LIM

12h 15m

1 stop

8:25 am - 12:09 am

LIM

DEN

16h 44m

2 stops

$471LATAM Airlines

Tue, Mar 3 - Tue, Mar 10

7:00 am - 10:00 pm

DEN

LIM

14h 00m

2 stops

12:15 am - 6:03 pm

LIM

DEN

18h 48m

2 stops

$479LATAM Airlines

Tue, May 5 - Tue, May 19

3:03 pm - 2:05 pm

DEN

SCL

21h 02m

2 stops

11:00 pm - 3:20 pm

SCL

DEN

18h 20m

2 stops

$570Delta

Wed, Apr 22 - Mon, Apr 27

11:43 am - 7:15 am

DEN

SCL

17h 32m

1 stop

8:40 pm - 12:26 am

SCL

DEN

29h 46m

1 stop

$574Delta

Sun, Apr 19 - Tue, Apr 28

Delta flights from Denver to South America

Our best Delta deals on Denver to South America flight tickets

Delta

Apr 5

DEN12:55 amDenver Intl

17h 20m

1 stop

BOG7:15 pmBogotá El Dorado

Apr 21

BOG5:00 amBogotá El Dorado

20h 26m

2 stops

DEN12:26 amDenver Intl

$405

Delta

Apr 7

DEN6:15 pmDenver Intl

22h 35m

2 stops

BOG5:50 pmBogotá El Dorado

Apr 19

BOG2:55 pmBogotá El Dorado

32h 08m

1 stop

DEN10:03 pmDenver Intl

$418

Delta

Mar 5

DEN12:59 amDenver Intl

11h 18m

1 stop

CTG2:17 pmCartagena Rafael Nunez

Mar 17

CTG2:30 pmCartagena Rafael Nunez

10h 39m

1 stop

DEN12:09 amDenver Intl

$429

LATAM Airlines flights from Denver to South America

Our best LATAM Airlines deals on Denver to South America flight tickets

LATAM Airlines

Apr 6

DEN7:05 amDenver Intl

12h 30m

2 stops

BOG8:35 pmBogotá El Dorado

Apr 20

BOG11:00 amBogotá El Dorado

14h 26m

2 stops

DEN12:26 amDenver Intl

$410

LATAM Airlines

Feb 3

DEN7:05 amDenver Intl

10h 25m

1 stop

BOG7:30 pmBogotá El Dorado

Feb 4

BOG9:00 amBogotá El Dorado

15h 50m

1 stop

DEN10:50 pmDenver Intl

$411

LATAM Airlines

Feb 3

DEN7:05 amDenver Intl

11h 15m

2 stops

BOG8:20 pmBogotá El Dorado

Feb 4

BOG7:00 amBogotá El Dorado

17h 50m

2 stops

DEN10:50 pmDenver Intl

$416

Fly from

Fly to

Route

Depart

Return

Price

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Mon 2/23

9:38 pm-11:01 am

1 stop11h 23m

Cartagena Rafael Nunez

Sat 3/7

6:25 am-5:16 pm

1 stop12h 51m

$325

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sat 2/28

11:59 pm-3:30 pm

2 stops13h 31m

Cartagena Rafael Nunez

Wed 3/11

1:28 pm-11:59 pm

1 stop11h 31m

$330

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Mon 4/6

2:14 pm-12:09 pm

2 stops20h 55m

Cartagena Rafael Nunez

Fri 4/17

1:25 pm-9:38 am

2 stops21h 13m

$342

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Thu 3/5

9:48 pm-8:06 am

1 stop8h 18m

Cartagena Rafael Nunez

Thu 3/12

9:22 am-6:16 pm

1 stop9h 54m

$345

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sun 4/26

8:23 pm-7:20 pm

1 stop21h 57m

Bogotá El Dorado

Fri 5/1

8:30 am-2:26 pm

1 stop30h 56m

$348

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Tue 4/7

7:45 am-7:20 pm

1 stop10h 35m

Bogotá El Dorado

Fri 4/24

12:14 am-8:38 am

1 stop9h 24m

$355

DenverLima

DEN - LIM

DENLIM

Denver Intl

Tue 3/3

2:45 pm-5:00 am

1 stop12h 15m

Lima J Chavez Intl

Tue 3/10

8:25 am-12:09 am

2 stops16h 44m

$471

DenverLima

DEN - LIM

DENLIM

Denver Intl

Tue 5/5

7:00 am-10:00 pm

2 stops14h 00m

Lima J Chavez Intl

Tue 5/19

12:15 am-6:03 pm

2 stops18h 48m

$479

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 4/22

3:03 pm-2:05 pm

2 stops21h 02m

Santiago Arturo Merino Benitez

Mon 4/27

11:00 pm-3:20 pm

2 stops18h 20m

$570

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 4/19

11:43 am-7:15 am

1 stop17h 32m

Santiago Arturo Merino Benitez

Tue 4/28

8:40 pm-12:26 am

1 stop29h 46m

$574

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Denver to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $504. If you aren’t able to travel during the month of November, then book flights to South America from Denver during October instead. Flights to South America in October, while not as cheap as those in November, still average around $545.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $622 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Denver for as low as $549 on momondo.

Can stopping save me money on Denver to South America flights?

You could potentially save up to 11% on your flight if you consider stops on a Denver to South America flight.

Cheap Denver to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to South America

Fastest flight time	8h 16m
Direct flights	None

The fastest flight from Denver to South America takes 8h 16m

There are no direct flights from Denver to South America. There are no popular flight routes from Denver to South America.

Search flight deals

When did momondo last update prices for flights from Denver Intl Airport to South America?
Prices for flights from Denver Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Denver Intl Airport to South America?
As of January 2026, there are 8 operators available to choose from for flights from Denver Intl Airport to South America.
How old do you have to be to fly from Denver Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Denver to South America

Compare and see reviews for airlines that fly from Denver to South America with momondo

Airline	Rating	Free Cancellation	Price
Volaris	PriceFrom $168	Free Cancellation	Rating 6.6 1,172 reviews	Search Volaris flights
Delta	PriceFrom $230	Free Cancellation	Rating 7.9 8,088 reviews	Search Delta flights
United Airlines	PriceFrom $299	Free Cancellation	Rating 7.4 9,191 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $325	Free Cancellation	Rating 7.6 1,557 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $330	Free Cancellation	Rating 7.2 11,174 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $336	Free Cancellation	Rating 7.5 1,913 reviews	Search LATAM Airlines flights
Aeromexico	PriceFrom $557	Free Cancellation	Rating 7.4 1,595 reviews	Search Aeromexico flights
Air Canada	PriceFrom $930	Free Cancellation	Rating 7.1 10,646 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to South America?

It is quick and easy to find Denver to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from Denver to South America with flexible booking policies on momondo?

Flights from Denver to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to South America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South America from Denver.

I’m not ready to book a flight from Denver to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.