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Cheap flights from Columbus to St. Louis from $64

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus to St. Louis departing on 1/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:03 pm - 9:07 amCMH-STL
14h 04m1 stop
Frontier Logo
7:45 pm - 7:08 pmSTL-CMH
22h 23m1 stop
$185Frontier
Find Deal
Mon, Nov 3 - Thu, Nov 6
Frontier Logo
11:09 am - 1:17 pmCMH-STL
27h 08m1 stop
Frontier Logo
7:45 pm - 7:08 pmSTL-CMH
22h 23m1 stop
$189Frontier
Find Deal
Sun, Nov 2 - Thu, Nov 6
Multiple Airlines Logo
8:03 pm - 9:07 amCMH-STL
14h 04m1 stop
Multiple Airlines Logo
11:07 am - 11:10 pmSTL-CMH
11h 03m2 stops
$210Multiple Airlines
Find Deal
Mon, Nov 3 - Thu, Nov 6
Multiple Airlines Logo
4:15 pm - 10:33 pmCMH-STL
7h 18m1 stop
Multiple Airlines Logo
12:20 pm - 9:12 pmSTL-CMH
7h 52m1 stop
$219Multiple Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
Multiple Airlines Logo
8:03 pm - 9:07 amCMH-STL
14h 04m1 stop
Multiple Airlines Logo
7:24 pm - 2:13 pmSTL-CMH
17h 49m1 stop
$234Multiple Airlines
Find Deal
Mon, Nov 17 - Wed, Nov 19
Delta Logo
7:58 pm - 11:42 pmCMH-STL
4h 44m1 stop
Delta Logo
6:00 am - 11:38 amSTL-CMH
4h 38m1 stop
$277Delta
Find Deal
Thu, Dec 4 - Thu, Dec 11
Delta Logo
12:33 pm - 4:06 pmCMH-STL
4h 33m1 stop
Delta Logo
1:59 pm - 8:54 pmSTL-CMH
5h 55m1 stop
$283Delta
Find Deal
Tue, Dec 2 - Tue, Dec 9
Southwest Logo
6:15 pm - 6:50 pmCMH-STL
1h 35mnonstop
Southwest Logo
6:40 pm - 9:00 pmSTL-CMH
1h 20mnonstop
$328Southwest
Find Deal
Thu, Jan 22 - Sun, Jan 25
Southwest Logo
2:50 pm - 5:15 pmCMH-STL
3h 25m1 stop
Southwest Logo
2:15 pm - 7:35 pmSTL-CMH
4h 20m1 stop
$329Southwest
Find Deal
Sat, Dec 20 - Sun, Dec 21
American Airlines Logo
6:56 am - 9:27 amCMH-STL
3h 31m1 stop
American Airlines Logo
11:18 am - 3:26 pmSTL-CMH
3h 08m1 stop
$453American Airlines
Find Deal
Thu, Feb 12 - Mon, Feb 16

Southwest flights from Columbus to St. Louis

Our best Southwest deals on Columbus to St. Louis flight tickets
Southwest
Jan 22
CMH6:15 pmColumbus
1h 35m
STL6:50 pmLambert-St Louis
Jan 25
STL6:40 pmLambert-St Louis
1h 20m
CMH9:00 pmColumbus
$328
Find similar
Southwest
Dec 20
CMH2:50 pmColumbus
3h 25m
1 stop
STL5:15 pmLambert-St Louis
Dec 21
STL2:15 pmLambert-St Louis
4h 20m
1 stop
CMH7:35 pmColumbus
$329
Find similar
Southwest
Dec 20
CMH6:00 pmColumbus
6h 20m
1 stop
STL11:20 pmLambert-St Louis
Dec 21
STL3:00 pmLambert-St Louis
7h 00m
2 stops
CMH11:00 pmColumbus
$334
Find similar

Frontier flights from Columbus to St. Louis

Our best Frontier deals on Columbus to St. Louis flight tickets
Frontier
Nov 3
CMH8:03 pmColumbus
14h 04m
1 stop
STL9:07 amLambert-St Louis
Nov 6
STL7:45 pmLambert-St Louis
22h 23m
1 stop
CMH7:08 pmColumbus
$185
Find similar
Frontier
Nov 2
CMH11:09 amColumbus
27h 08m
1 stop
STL1:17 pmLambert-St Louis
Nov 6
STL7:45 pmLambert-St Louis
22h 23m
1 stop
CMH7:08 pmColumbus
$189
Find similar
Frontier
Nov 2
CMH11:09 amColumbus
22h 58m
2 stops
STL9:07 amLambert-St Louis
Nov 6
STL11:07 amLambert-St Louis
27h 28m
1 stop
CMH3:35 pmColumbus
$281
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbus to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Columbus to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Mon 11/3

8:03 pm-9:07 am

1 stop14h 04m

Lambert-St Louis

Thu 11/6

7:45 pm-7:08 pm

1 stop22h 23m

$185

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Sun 11/2

11:09 am-1:17 pm

1 stop27h 08m

Lambert-St Louis

Thu 11/6

7:45 pm-7:08 pm

1 stop22h 23m

$189

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Mon 11/3

8:03 pm-9:07 am

1 stop14h 04m

Lambert-St Louis

Thu 11/6

11:07 am-11:10 pm

2 stops11h 03m

$210

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Thu 1/22

4:15 pm-10:33 pm

1 stop7h 18m

Lambert-St Louis

Sun 1/25

12:20 pm-9:12 pm

1 stop7h 52m

$219

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Mon 11/17

8:03 pm-9:07 am

1 stop14h 04m

Lambert-St Louis

Wed 11/19

7:24 pm-2:13 pm

1 stop17h 49m

$234

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Thu 12/4

7:58 pm-11:42 pm

1 stop4h 44m

Lambert-St Louis

Thu 12/11

6:00 am-11:38 am

1 stop4h 38m

$277

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Tue 12/2

12:33 pm-4:06 pm

1 stop4h 33m

Lambert-St Louis

Tue 12/9

1:59 pm-8:54 pm

1 stop5h 55m

$283

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Thu 1/22

6:15 pm-6:50 pm

Nonstop1h 35m

Lambert-St Louis

Sun 1/25

6:40 pm-9:00 pm

Nonstop1h 20m

$328

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Sat 12/20

2:50 pm-5:15 pm

1 stop3h 25m

Lambert-St Louis

Sun 12/21

2:15 pm-7:35 pm

1 stop4h 20m

$329

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Thu 2/12

6:56 am-9:27 am

1 stop3h 31m

Lambert-St Louis

Mon 2/16

11:18 am-3:26 pm

1 stop3h 08m

$453

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Columbus to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, May is the cheapest month to fly from Columbus to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $254. The month of April is another great option to travel to St. Louis, with average flight prices from Columbus averaging around $268.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Saturday when prices can be found for as low as $371. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $424. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Columbus at noon is the least expensive time of day to depart. momondo users have found prices as low as $341 when looking at flights departing at noon. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $407 per ticket.

What is the cheapest Columbus to Lambert-St Louis flight route?

Fly from Columbus to Lambert-St Louis for the best Columbus - Lambert-St Louis flight prices

What cabin class options are available on Columbus to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on Columbus to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Columbus to St. Louis flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to St. Louis

Fastest flight time

1h 25m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in St. Louis

1 airport
The fastest flight from Columbus to St. Louis takes 1h 25m
Direct flights go from Columbus to St. Louis on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
Search flight deals

  • How far is Columbus to Lambert-St Louis by plane?

    The distance between Columbus and Lambert-St Louis is about 395.8 mi. Flights usually cover this in 1h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbus to Lambert-St Louis Airport?

    Prices for flights from Columbus to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbus to Lambert-St Louis Airport?

  • How old do you have to be to fly from Columbus to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbus to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The necessary travel and health documents for your Lambert-St Louis Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Columbus to St. Louis

Compare and see reviews for airlines that fly from Columbus to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $188Free CancellationRating
7.2
11,024 reviews
Search American Airlines flights
United AirlinesPriceFrom $222Free CancellationRating
7.4
8,991 reviews
Search United Airlines flights
SouthwestPriceFrom $224Free CancellationRating
8.0
4,239 reviews
Search Southwest flights
DeltaPriceFrom $228Free CancellationRating
7.9
7,978 reviews
Search Delta flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Wentzville
Collinsville
Fenton
St. Peters
Alton
Farmington
Festus
Glencoe
Clayton
Edwardsville
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to St. Louis?

Finding the right flight to St. Louis from Columbus is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to St. Louis quick and easy, saving you time and money.

Can I find flights from Columbus to St. Louis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to St. Louis from Columbus with this policy.

How can momondo help me find flights from Columbus to St. Louis?

Once you have performed a search for Columbus to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Columbus to St. Louis right now. Can momondo alert me if prices change?

If you are simply researching potential flights to St. Louis, momondo offers a useful price alert feature which will track prices for flights to St. Louis from Columbus and alert you when they change.

An easier way to manage your St. Louis trip

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