How many flights depart from Columbia, Missouri to South Carolina on average per week?

6 flights are operational weekly from Columbia, Missouri to South Carolina as of July 2026. The most popular departure day for this route is Mon, with 17% of flights per week taking off on this day.

What is the cheapest airline that flies from Columbia Regional to South Carolina?

United Airlines is the most popular carrier operating from Columbia Regional to South Carolina

When did momondo last update prices for flights from Columbia Regional Airport to South Carolina?

Prices for flights from Columbia Regional Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Columbia Regional Airport to South Carolina?

The number of operators available for flights from Columbia Regional Airport to South Carolina is 2 as of July 2026.

How old do you have to be to fly from Columbia Regional Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$144 Cheap Flights from Columbia, Missouri to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Columbia, Missouri to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:34 am - 8:01 am

COU

CLT

20h 27m

1 stop

11:50 am - 9:09 am

CLT

COU

22h 19m

2 stops

$283Multiple Airlines

Mon, Aug 24 - Thu, Aug 27

10:34 am - 8:01 am

COU

CLT

20h 27m

1 stop

2:45 pm - 9:09 am

CLT

COU

19h 24m

1 stop

$287Multiple Airlines

Mon, Aug 24 - Thu, Aug 27

9:59 am - 8:01 am

COU

CLT

21h 02m

1 stop

2:45 pm - 9:49 am

CLT

COU

20h 04m

1 stop

$288Multiple Airlines

Fri, Aug 28 - Sun, Aug 30

10:34 am - 8:01 am

COU

CLT

20h 27m

1 stop

8:56 am - 9:49 am

CLT

COU

25h 53m

1 stop

$288Multiple Airlines

Mon, Aug 24 - Sun, Aug 30

7:10 am - 2:37 pm

COU

CHS

6h 27m

1 stop

2:05 pm - 8:46 pm

CHS

COU

7h 41m

1 stop

$308American Airlines

Sun, Sep 6 - Wed, Sep 9

7:27 am - 1:49 pm

COU

CHS

5h 22m

1 stop

4:59 pm - 10:42 pm

CHS

COU

6h 43m

1 stop

$308American Airlines

Sat, Nov 7 - Thu, Nov 12

11:19 am - 6:02 pm

COU

CHS

5h 43m

1 stop

8:00 am - 2:38 pm

CHS

COU

7h 38m

1 stop

$308United Airlines

Sat, Sep 26 - Sat, Oct 3

3:19 pm - 9:41 pm

COU

CHS

5h 22m

1 stop

6:30 am - 10:39 am

CHS

COU

5h 09m

1 stop

$308United Airlines

Sat, Sep 26 - Fri, Oct 2

6:22 pm - 12:24 am

COU

CHS

5h 02m

1 stop

4:59 pm - 10:42 pm

CHS

COU

6h 43m

1 stop

$308American Airlines

Sat, Nov 7 - Thu, Nov 12

11:17 am - 7:40 pm

COU

CHS

7h 23m

1 stop

6:30 am - 10:39 am

CHS

COU

5h 09m

1 stop

$308United Airlines

Thu, Sep 10 - Sun, Sep 13

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American Airlines flights from Columbia, Missouri to South Carolina

Our best American Airlines deals on Columbia, Missouri to South Carolina flight tickets

American Airlines

Nov 7

COU7:27 amColumbia Regional

5h 22m

1 stop

CHS1:49 pmCharleston

Nov 12

CHS4:59 pmCharleston

6h 43m

1 stop

COU10:42 pmColumbia Regional

$308

American Airlines

Sep 10

COU3:31 pmColumbia Regional

6h 28m

1 stop

CHS10:59 pmCharleston

Sep 13

CHS6:25 pmCharleston

5h 09m

1 stop

COU10:34 pmColumbia Regional

$323

American Airlines

Aug 11

COU12:43 pmColumbia Regional

5h 37m

1 stop

CHS7:20 pmCharleston

Aug 15

CHS12:21 pmCharleston

6h 36m

1 stop

COU5:57 pmColumbia Regional

$338

United Airlines flights from Columbia, Missouri to South Carolina

Our best United Airlines deals on Columbia, Missouri to South Carolina flight tickets

United Airlines

Sep 26

COU11:19 amColumbia Regional

11h 40m

2 stops

CHS11:59 pmCharleston

Oct 3

CHS6:50 pmCharleston

5h 05m

1 stop

COU10:55 pmColumbia Regional

$314

United Airlines

Sep 26

COU11:19 amColumbia Regional

11h 40m

2 stops

CHS11:59 pmCharleston

Oct 3

CHS6:00 amCharleston

9h 38m

2 stops

COU2:38 pmColumbia Regional

$319

United Airlines

Sep 10

COU11:17 amColumbia Regional

7h 23m

1 stop

CHS7:40 pmCharleston

Sep 13

CHS6:30 amCharleston

5h 09m

1 stop

COU10:39 amColumbia Regional

$328

momondo Fare Finder

Use the filters below to find and compare flights from Columbia, Missouri to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Mon 8/24

10:34 am-8:01 am

1 stop20h 27m

Charlotte Douglas

Thu 8/27

11:50 am-9:09 am

2 stops22h 19m

$283

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Mon 8/24

10:34 am-8:01 am

1 stop20h 27m

Charlotte Douglas

Thu 8/27

2:45 pm-9:09 am

1 stop19h 24m

$287

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Fri 8/28

9:59 am-8:01 am

1 stop21h 02m

Charlotte Douglas

Sun 8/30

2:45 pm-9:49 am

1 stop20h 04m

$288

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Mon 8/24

10:34 am-8:01 am

1 stop20h 27m

Charlotte Douglas

Sun 8/30

8:56 am-9:49 am

1 stop25h 53m

$288

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sun 9/6

7:10 am-2:37 pm

1 stop6h 27m

Charleston

Wed 9/9

2:05 pm-8:46 pm

1 stop7h 41m

$308

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 11/7

7:27 am-1:49 pm

1 stop5h 22m

Charleston

Thu 11/12

4:59 pm-10:42 pm

1 stop6h 43m

$308

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 9/26

11:19 am-6:02 pm

1 stop5h 43m

Charleston

Sat 10/3

8:00 am-2:38 pm

1 stop7h 38m

$308

Quickest round-trip

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 9/26

3:19 pm-9:41 pm

1 stop5h 22m

Charleston

Fri 10/2

6:30 am-10:39 am

1 stop5h 09m

$308

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 11/7

6:22 pm-12:24 am

1 stop5h 02m

Charleston

Thu 11/12

4:59 pm-10:42 pm

1 stop6h 43m

$308

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Thu 9/10

11:17 am-7:40 pm

1 stop7h 23m

Charleston

Sun 9/13

6:30 am-10:39 am

1 stop5h 09m

$308

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Columbia, Missouri to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Columbia, Missouri is in October. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of October, then book flights to South Carolina from Columbia, Missouri during May instead. Flights to South Carolina in May, while not as cheap as those in October, still average around $0.

Can stopping save me money on Columbia, Missouri to South Carolina flights?

You could potentially save up to 24% on your flight if you consider stops on a Columbia, Missouri to South Carolina flight.

Cheap Columbia, Missouri to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to South Carolina

Fastest flight time	2h 05m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Columbia, Missouri to South Carolina takes 2h 05m

Direct flights go from Columbia, Missouri to South Carolina every day.

There are 57 airports in South Carolina. From Columbia, Missouri there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Columbia, Missouri to South Carolina

When did momondo last update prices for flights from Columbia Regional Airport to South Carolina?
Prices for flights from Columbia Regional Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Columbia Regional Airport to South Carolina?
The number of operators available for flights from Columbia Regional Airport to South Carolina is 2 as of July 2026.
How old do you have to be to fly from Columbia Regional Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbia, Missouri to South Carolina

Compare and see reviews for airlines that fly from Columbia, Missouri to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $258	Free Cancellation	Rating 7.4 10,053 reviews		Search United Airlines flights
American Airlines	PriceFrom $298	Free Cancellation	Rating 7.1 11,846 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Columbia on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbia to South Carolina?

Once all potential Columbia to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Columbia to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.