What is the cheapest airline that flies from Columbia Regional to South Carolina?

Allegiant Air, American Airlines, and United Airlines are the most popular carriers operating from Columbia Regional to South Carolina

When did momondo last update prices for flights from Columbia Regional Airport to South Carolina?

Prices for flights from Columbia Regional Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Columbia Regional Airport to South Carolina?

The number of operators available for flights from Columbia Regional Airport to South Carolina is 1 as of April 2026.

How old do you have to be to fly from Columbia Regional Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$169 Cheap Flights from Columbia to South Carolina in 2026

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Find the cheapest flights from Columbia, Missouri to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:05 pm - 9:48 pm

COU

CHS

5h 43m

1 stop

3:25 pm - 9:49 pm

CHS

COU

7h 24m

1 stop

$298United Airlines

Wed, Aug 26 - Wed, Sep 2

3:05 pm - 9:48 pm

COU

CHS

5h 43m

1 stop

2:51 pm - 9:49 pm

CHS

COU

7h 58m

2 stops

$304United Airlines

Wed, Aug 26 - Wed, Sep 2

3:05 pm - 9:51 pm

COU

CHS

5h 46m

1 stop

6:00 am - 10:48 am

CHS

COU

5h 48m

1 stop

$318United Airlines

Mon, Jun 8 - Wed, Jun 24

3:05 pm - 9:51 pm

COU

CHS

5h 46m

1 stop

10:00 am - 9:59 pm

CHS

COU

12h 59m

2 stops

$324United Airlines

Mon, Jun 8 - Wed, Jun 24

8:00 am - 1:55 pm

COU

CHS

4h 55m

1 stop

8:55 am - 2:30 pm

CHS

COU

6h 35m

1 stop

$343United Airlines

Wed, Aug 26 - Sun, Aug 30

10:32 am - 8:03 pm

COU

MYR

8h 31m

2 stops

6:10 pm - 10:46 pm

MYR

COU

5h 36m

1 stop

$349American Airlines

Sat, Jul 25 - Wed, Jul 29

11:30 am - 11:53 pm

COU

CHS

11h 23m

2 stops

11:08 am - 9:49 pm

CHS

COU

11h 41m

2 stops

$351United Airlines

Wed, Aug 26 - Wed, Sep 2

7:16 am - 10:30 am

COU

CLT

2h 14mnonstop

9:28 pm - 10:46 pm

CLT

COU

2h 18mnonstop

$357American Airlines

Thu, May 28 - Sat, May 30

5:19 pm - 12:08 am

COU

MYR

5h 49m

1 stop

6:10 pm - 10:40 pm

MYR

COU

5h 30m

1 stop

$361American Airlines

Sat, Jul 25 - Wed, Jul 29

5:19 pm - 12:53 am

COU

CLT

6h 34m

1 stop

9:28 pm - 10:46 pm

CLT

COU

2h 18mnonstop

$366American Airlines

Thu, May 28 - Sat, May 30

American Airlines flights from Columbia, Missouri to South Carolina

Our best American Airlines deals on Columbia, Missouri to South Carolina flight tickets

American Airlines

Jul 25

COU10:32 amColumbia Regional

8h 31m

2 stops

MYR8:03 pmMyrtle Beach Intl

Jul 29

MYR6:10 pmMyrtle Beach Intl

5h 36m

1 stop

COU10:46 pmColumbia Regional

$349

American Airlines

May 28

COU7:16 amColumbia Regional

2h 14m

CLT10:30 amCharlotte Douglas

May 30

CLT9:28 pmCharlotte Douglas

2h 18m

COU10:46 pmColumbia Regional

$357

American Airlines

Jul 25

COU5:19 pmColumbia Regional

5h 49m

1 stop

MYR12:08 amMyrtle Beach Intl

Jul 29

MYR6:10 pmMyrtle Beach Intl

5h 30m

1 stop

COU10:40 pmColumbia Regional

$361

United Airlines flights from Columbia, Missouri to South Carolina

Our best United Airlines deals on Columbia, Missouri to South Carolina flight tickets

United Airlines

Aug 26

COU3:05 pmColumbia Regional

5h 43m

1 stop

CHS9:48 pmCharleston

Sep 2

CHS3:25 pmCharleston

7h 24m

1 stop

COU9:49 pmColumbia Regional

$298

United Airlines

Aug 26

COU3:05 pmColumbia Regional

5h 43m

1 stop

CHS9:48 pmCharleston

Sep 2

CHS2:51 pmCharleston

7h 58m

2 stops

COU9:49 pmColumbia Regional

$304

United Airlines

Jun 8

COU3:05 pmColumbia Regional

5h 46m

1 stop

CHS9:51 pmCharleston

Jun 24

CHS6:00 amCharleston

5h 48m

1 stop

COU10:48 amColumbia Regional

$318

momondo Fare Finder

Use the filters below to find and compare flights from Columbia, Missouri to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Wed 8/26

3:05 pm-9:48 pm

1 stop5h 43m

Charleston

Wed 9/2

3:25 pm-9:49 pm

1 stop7h 24m

$298

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Wed 8/26

3:05 pm-9:48 pm

1 stop5h 43m

Charleston

Wed 9/2

2:51 pm-9:49 pm

2 stops7h 58m

$304

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Mon 6/8

3:05 pm-9:51 pm

1 stop5h 46m

Charleston

Wed 6/24

6:00 am-10:48 am

1 stop5h 48m

$318

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Mon 6/8

3:05 pm-9:51 pm

1 stop5h 46m

Charleston

Wed 6/24

10:00 am-9:59 pm

2 stops12h 59m

$324

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Wed 8/26

8:00 am-1:55 pm

1 stop4h 55m

Charleston

Sun 8/30

8:55 am-2:30 pm

1 stop6h 35m

$343

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Sat 7/25

10:32 am-8:03 pm

2 stops8h 31m

Myrtle Beach Intl

Wed 7/29

6:10 pm-10:46 pm

1 stop5h 36m

$349

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Wed 8/26

11:30 am-11:53 pm

2 stops11h 23m

Charleston

Wed 9/2

11:08 am-9:49 pm

2 stops11h 41m

$351

Quickest round-trip

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Thu 5/28

7:16 am-10:30 am

Nonstop2h 14m

Charlotte Douglas

Sat 5/30

9:28 pm-10:46 pm

Nonstop2h 18m

$357

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Sat 7/25

5:19 pm-12:08 am

1 stop5h 49m

Myrtle Beach Intl

Wed 7/29

6:10 pm-10:40 pm

1 stop5h 30m

$361

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Thu 5/28

5:19 pm-12:53 am

1 stop6h 34m

Charlotte Douglas

Sat 5/30

9:28 pm-10:46 pm

Nonstop2h 18m

$366

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Columbia, Missouri to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Columbia, Missouri to South Carolina flights?

You could potentially save up to 10% on your flight if you consider stops on a Columbia, Missouri to South Carolina flight.

Cheap Columbia, Missouri to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to South Carolina

Fastest flight time	4h 50m
Direct flights	Tue, Wed, Fri and Sun
Airports in South Carolina	57 airports

The fastest flight from Columbia, Missouri to South Carolina takes 4h 50m

Direct flights go from Columbia, Missouri to South Carolina on Tuesday, Wednesday, Friday and Sunday. There are no airlines offering direct flights.

There are 57 airports in South Carolina. From Columbia, Missouri there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Columbia, Missouri to South Carolina

When did momondo last update prices for flights from Columbia Regional Airport to South Carolina?
Prices for flights from Columbia Regional Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Columbia Regional Airport to South Carolina?
The number of operators available for flights from Columbia Regional Airport to South Carolina is 1 as of April 2026.
How old do you have to be to fly from Columbia Regional Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbia, Missouri to South Carolina

Compare and see reviews for airlines that fly from Columbia, Missouri to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $323	Free Cancellation	Rating 7.1 11,681 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Columbia on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbia to South Carolina?

Once all potential Columbia to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Columbia to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.