How many flights depart from Columbia, Missouri to South Carolina on average per week?

7 flights are operational weekly from Columbia, Missouri to South Carolina as of June 2026. The most popular departure day for this route is Mon, with 14% of flights per week taking off on this day.

What is the cheapest airline that flies from Columbia Regional to South Carolina?

United Airlines, American Airlines, and Allegiant Air are the most popular carriers operating from Columbia Regional to South Carolina

When did momondo last update prices for flights from Columbia Regional Airport to South Carolina?

Prices for flights from Columbia Regional Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Columbia Regional Airport to South Carolina?

The number of operators available for flights from Columbia Regional Airport to South Carolina is 1 as of June 2026.

How old do you have to be to fly from Columbia Regional Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$183 Cheap Flights from Columbia, Missouri to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Columbia, Missouri to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:39 am - 8:38 am

COU

CHS

21h 59m

1 stop

3:23 pm - 8:49 am

CHS

COU

18h 26m

1 stop

$255Multiple Airlines

Sat, Jul 4 - Fri, Jul 10

12:24 pm - 6:07 pm

COU

CHS

4h 43m

1 stop

6:32 pm - 10:35 pm

CHS

COU

5h 03m

1 stop

$298American Airlines

Mon, Nov 9 - Sat, Nov 14

3:12 pm - 9:34 pm

COU

CHS

5h 22m

1 stop

11:10 am - 10:55 pm

CHS

COU

12h 45m

2 stops

$304United Airlines

Sat, Aug 22 - Wed, Aug 26

6:15 am - 3:10 pm

COU

CHS

7h 55m

2 stops

11:10 am - 10:55 pm

CHS

COU

12h 45m

2 stops

$309United Airlines

Sat, Aug 22 - Wed, Aug 26

6:15 am - 3:10 pm

COU

CHS

7h 55m

2 stops

3:20 pm - 10:55 pm

CHS

COU

8h 35m

2 stops

$313United Airlines

Fri, Aug 21 - Tue, Aug 25

9:39 am - 10:47 pm

COU

CHS

36h 08m

2 stops

3:23 pm - 8:49 am

CHS

COU

18h 26m

1 stop

$320Multiple Airlines

Sat, Jul 4 - Fri, Jul 10

3:12 pm - 9:34 pm

COU

CHS

5h 22m

1 stop

4:58 pm - 10:34 pm

CHS

COU

6h 36m

1 stop

$338United Airlines

Sat, Sep 5 - Sat, Sep 12

12:24 pm - 6:07 pm

COU

CHS

4h 43m

1 stop

6:32 pm - 10:35 pm

CHS

COU

5h 03m

1 stop

$343American Airlines

Mon, Nov 9 - Sat, Nov 14

10:49 am - 11:52 pm

COU

CHS

12h 03m

2 stops

6:00 am - 10:13 am

CHS

COU

5h 13m

1 stop

$349United Airlines

Tue, Jul 14 - Sat, Aug 1

7:30 am - 10:45 am

COU

CLT

2h 15mnonstop

8:52 pm - 10:06 pm

CLT

COU

2h 14mnonstop

$373American Airlines

Wed, Aug 12 - Sat, Aug 15

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American Airlines flights from Columbia, Missouri to South Carolina

Our best American Airlines deals on Columbia, Missouri to South Carolina flight tickets

American Airlines

Nov 9

COU12:24 pmColumbia Regional

4h 43m

1 stop

CHS6:07 pmCharleston

Nov 14

CHS6:32 pmCharleston

5h 03m

1 stop

COU10:35 pmColumbia Regional

$298

American Airlines

Nov 9

COU12:24 pmColumbia Regional

4h 43m

1 stop

CHS6:07 pmCharleston

Nov 14

CHS6:32 pmCharleston

5h 03m

1 stop

COU10:35 pmColumbia Regional

$343

American Airlines

Aug 12

COU7:30 amColumbia Regional

2h 15m

CLT10:45 amCharlotte Douglas

Aug 15

CLT8:52 pmCharlotte Douglas

2h 14m

COU10:06 pmColumbia Regional

$373

United Airlines flights from Columbia, Missouri to South Carolina

Our best United Airlines deals on Columbia, Missouri to South Carolina flight tickets

United Airlines

Aug 22

COU3:12 pmColumbia Regional

5h 22m

1 stop

CHS9:34 pmCharleston

Aug 26

CHS11:10 amCharleston

12h 45m

2 stops

COU10:55 pmColumbia Regional

$304

United Airlines

Aug 22

COU6:15 amColumbia Regional

7h 55m

2 stops

CHS3:10 pmCharleston

Aug 26

CHS11:10 amCharleston

12h 45m

2 stops

COU10:55 pmColumbia Regional

$309

United Airlines

Aug 21

COU6:15 amColumbia Regional

7h 55m

2 stops

CHS3:10 pmCharleston

Aug 25

CHS3:20 pmCharleston

8h 35m

2 stops

COU10:55 pmColumbia Regional

$313

momondo Fare Finder

Use the filters below to find and compare flights from Columbia, Missouri to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 7/4

9:39 am-8:38 am

1 stop21h 59m

Charleston

Fri 7/10

3:23 pm-8:49 am

1 stop18h 26m

$255

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Mon 11/9

12:24 pm-6:07 pm

1 stop4h 43m

Charleston

Sat 11/14

6:32 pm-10:35 pm

1 stop5h 03m

$298

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 8/22

3:12 pm-9:34 pm

1 stop5h 22m

Charleston

Wed 8/26

11:10 am-10:55 pm

2 stops12h 45m

$304

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 8/22

6:15 am-3:10 pm

2 stops7h 55m

Charleston

Wed 8/26

11:10 am-10:55 pm

2 stops12h 45m

$309

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Fri 8/21

6:15 am-3:10 pm

2 stops7h 55m

Charleston

Tue 8/25

3:20 pm-10:55 pm

2 stops8h 35m

$313

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 7/4

9:39 am-10:47 pm

2 stops36h 08m

Charleston

Fri 7/10

3:23 pm-8:49 am

1 stop18h 26m

$320

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 9/5

3:12 pm-9:34 pm

1 stop5h 22m

Charleston

Sat 9/12

4:58 pm-10:34 pm

1 stop6h 36m

$338

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Mon 11/9

12:24 pm-6:07 pm

1 stop4h 43m

Charleston

Sat 11/14

6:32 pm-10:35 pm

1 stop5h 03m

$343

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Tue 7/14

10:49 am-11:52 pm

2 stops12h 03m

Charleston

Sat 8/1

6:00 am-10:13 am

1 stop5h 13m

$349

Quickest round-trip

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Wed 8/12

7:30 am-10:45 am

Nonstop2h 15m

Charlotte Douglas

Sat 8/15

8:52 pm-10:06 pm

Nonstop2h 14m

$373

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Columbia, Missouri to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

Can stopping save me money on Columbia, Missouri to South Carolina flights?

You could potentially save up to 24% on your flight if you consider stops on a Columbia, Missouri to South Carolina flight.

Cheap Columbia, Missouri to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to South Carolina

Fastest flight time	2h 05m
Direct flights	Mon, Wed, Thu, Fri, Sat and Sun
Airports in South Carolina	57 airports

The fastest flight from Columbia, Missouri to South Carolina takes 2h 05m

Direct flights go from Columbia, Missouri to South Carolina on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.

There are 57 airports in South Carolina. From Columbia, Missouri there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Columbia, Missouri to South Carolina

When did momondo last update prices for flights from Columbia Regional Airport to South Carolina?
Prices for flights from Columbia Regional Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Columbia Regional Airport to South Carolina?
The number of operators available for flights from Columbia Regional Airport to South Carolina is 1 as of June 2026.
How old do you have to be to fly from Columbia Regional Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbia, Missouri to South Carolina

Compare and see reviews for airlines that fly from Columbia, Missouri to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $323	Free Cancellation	Rating 7.1 11,660 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to South Carolina?

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Can I find flights from Columbia to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Columbia on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbia to South Carolina?

Once all potential Columbia to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Columbia to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.