Latest deals
Insights
FAQs
Price Alerts

Cheap flights from Colorado to Florence from $579

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Colorado to Florence departing on 2/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Colorado to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
9:30 am - 5:21 pm
DEN
-
FLO
5h 51m
1 stop
American Airlines Logo
5:16 am - 10:51 am
FLO
-
DEN
7h 35m
1 stop
$579American Airlines
Τρι, Φεβ 17 - Σαβ, Φεβ 21
American Airlines Logo
1:25 pm - 11:08 pm
DEN
-
FLO
7h 43m
1 stop
American Airlines Logo
5:16 am - 1:57 pm
FLO
-
DEN
10h 41m
2 stops
$584American Airlines
Τρι, Φεβ 17 - Σαβ, Φεβ 21
American Airlines Logo
10:20 am - 11:08 pm
DEN
-
FLO
10h 48m
2 stops
American Airlines Logo
5:16 am - 1:57 pm
FLO
-
DEN
10h 41m
2 stops
$589American Airlines
Τρι, Φεβ 17 - Σαβ, Φεβ 21
American Airlines Logo
8:07 am - 5:50 pm
DEN
-
FLO
7h 43m
1 stop
American Airlines Logo
6:20 pm - 10:42 pm
FLO
-
DEN
6h 22m
1 stop
$709American Airlines
Παρ, Μαρ 20 - Κυρ, Μαρ 22
American Airlines Logo
7:00 am - 11:57 pm
DEN
-
FLO
14h 57m
2 stops
American Airlines Logo
6:20 pm - 10:42 pm
FLO
-
DEN
6h 22m
1 stop
$826American Airlines
Παρ, Μαρ 20 - Κυρ, Μαρ 22
American Airlines Logo
7:00 am - 11:57 pm
DEN
-
FLO
14h 57m
2 stops
American Airlines Logo
6:20 pm - 8:47 am
FLO
-
DEN
16h 27m
2 stops
$978American Airlines
Παρ, Μαρ 20 - Κυρ, Μαρ 22

American Airlines flights from Colorado to Florence, South Carolina

Our best American Airlines deals on Colorado to Florence, South Carolina flight tickets
American Airlines
Feb 17
DEN9:30 amDenver Intl
5h 51m
1 stop
FLO5:21 pmFlorence
Feb 21
FLO5:16 amFlorence
7h 35m
1 stop
DEN10:51 amDenver Intl
$579
American Airlines
Feb 17
DEN1:25 pmDenver Intl
7h 43m
1 stop
FLO11:08 pmFlorence
Feb 21
FLO5:16 amFlorence
10h 41m
2 stops
DEN1:57 pmDenver Intl
$584
American Airlines
Feb 17
DEN10:20 amDenver Intl
10h 48m
2 stops
FLO11:08 pmFlorence
Feb 21
FLO5:16 amFlorence
10h 41m
2 stops
DEN1:57 pmDenver Intl
$589

momondo Fare Finder

 
Customize your flight search to find flights from Colorado to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Φεβρουάριος 3, 2026.
Use the filters below to find and compare flights from Colorado to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Τρι 2/17

9:30 am-5:21 pm

1 stop5h 51m

Florence

Σαβ 2/21

5:16 am-10:51 am

1 stop7h 35m

$579

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Τρι 2/17

1:25 pm-11:08 pm

1 stop7h 43m

Florence

Σαβ 2/21

5:16 am-1:57 pm

2 stops10h 41m

$584

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Τρι 2/17

10:20 am-11:08 pm

2 stops10h 48m

Florence

Σαβ 2/21

5:16 am-1:57 pm

2 stops10h 41m

$589

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Παρ 3/20

8:07 am-5:50 pm

1 stop7h 43m

Florence

Κυρ 3/22

6:20 pm-10:42 pm

1 stop6h 22m

$709

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Παρ 3/20

7:00 am-11:57 pm

2 stops14h 57m

Florence

Κυρ 3/22

6:20 pm-10:42 pm

1 stop6h 22m

$826

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Παρ 3/20

7:00 am-11:57 pm

2 stops14h 57m

Florence

Κυρ 3/22

6:20 pm-8:47 am

2 stops16h 27m

$978

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Colorado to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Frontier and United Airlines are the top three most popular airlines that fly to Florence, South Carolina from Colorado according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Colorado to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Colorado to Florence, South Carolina

Fastest flight time

5h 51m

Direct flights

None
The fastest flight from Colorado to Florence, South Carolina takes 5h 51m
There are no direct flights from Colorado to Florence, South Carolina. There are no popular flight routes from Colorado to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Colorado to Florence Airport?

    Prices for flights from Colorado to Florence Airport are updated daily.

  • How old do you have to be to fly from Colorado to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Colorado to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Colorado to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Colorado.

Can I find flights from Colorado to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Colorado with this policy.

How can momondo help me find flights from Colorado to Florence?

momondo provides multiple filters to help you find the best flight to Florence from Colorado. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Colorado to Florence right now. Can momondo alert me if prices change?

Price alerts on flights to Florence from Colorado are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Florence, South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Πεμ 3/5
Πεμ 3/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States