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Cheap flights from Colorado to Florence from $522

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Colorado to Florence departing on 11/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Colorado to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:13 pm - 10:53 pmDEN-FLO
5h 40m1 stop
American Airlines Logo
6:15 am - 12:41 pmFLO-DEN
8h 26m1 stop
$522American Airlines
Find Deal
Fri, Nov 14 - Fri, Dec 5
American Airlines Logo
9:11 am - 10:53 pmDEN-FLO
11h 42m2 stops
American Airlines Logo
5:35 pm - 11:05 pmFLO-DEN
7h 30m1 stop
$527American Airlines
Find Deal
Fri, Nov 14 - Fri, Dec 5
American Airlines Logo
9:11 am - 10:53 pmDEN-FLO
11h 42m2 stops
American Airlines Logo
10:28 am - 5:46 pmFLO-DEN
9h 18m2 stops
$532American Airlines
Find Deal
Fri, Nov 14 - Fri, Dec 5
American Airlines Logo
10:37 am - 12:15 amCOS-FLO
11h 38m2 stops
American Airlines Logo
11:15 am - 8:30 pmFLO-COS
11h 15m2 stops
$555American Airlines
Find Deal
Sat, Dec 13 - Tue, Dec 16
American Airlines Logo
7:00 am - 6:04 pmMTJ-FLO
9h 04m2 stops
American Airlines Logo
11:14 am - 7:19 pmFLO-MTJ
10h 05m2 stops
$571American Airlines
Find Deal
Sat, Nov 15 - Tue, Nov 18
American Airlines Logo
7:30 am - 10:53 pmGJT-FLO
13h 23m2 stops
American Airlines Logo
11:16 am - 8:49 pmFLO-GJT
11h 33m2 stops
$571American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
7:00 am - 6:04 pmMTJ-FLO
9h 04m2 stops
American Airlines Logo
11:14 am - 7:19 pmFLO-MTJ
10h 05m2 stops
$601American Airlines
Find Deal
Sat, Nov 15 - Tue, Nov 18
American Airlines Logo
7:00 am - 10:53 pmMTJ-FLO
13h 53m2 stops
American Airlines Logo
5:15 am - 7:48 pmFLO-MTJ
16h 33m2 stops
$690American Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16
American Airlines Logo
7:00 am - 10:53 pmMTJ-FLO
13h 53m3 stops
American Airlines Logo
5:15 am - 7:48 pmFLO-MTJ
16h 33m2 stops
$804American Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16
American Airlines Logo
7:00 am - 10:53 pmMTJ-FLO
13h 53m3 stops
American Airlines Logo
5:15 am - 7:48 pmFLO-MTJ
16h 33m3 stops
$1,010American Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16

American Airlines flights from Colorado to Florence, South Carolina

Our best American Airlines deals on Colorado to Florence, South Carolina flight tickets
American Airlines
Nov 14
DEN3:13 pmDenver Intl
5h 40m
1 stop
FLO10:53 pmFlorence
Dec 5
FLO6:15 amFlorence
8h 26m
1 stop
DEN12:41 pmDenver Intl
$522
Find similar
American Airlines
Nov 14
DEN9:11 amDenver Intl
11h 42m
2 stops
FLO10:53 pmFlorence
Dec 5
FLO5:35 pmFlorence
7h 30m
1 stop
DEN11:05 pmDenver Intl
$527
Find similar
American Airlines
Nov 14
DEN9:11 amDenver Intl
11h 42m
2 stops
FLO10:53 pmFlorence
Dec 5
FLO10:28 amFlorence
9h 18m
2 stops
DEN5:46 pmDenver Intl
$532
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Colorado to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Colorado to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Fri 11/14

3:13 pm-10:53 pm

1 stop5h 40m

Florence

Fri 12/5

6:15 am-12:41 pm

1 stop8h 26m

$522

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Fri 11/14

9:11 am-10:53 pm

2 stops11h 42m

Florence

Fri 12/5

5:35 pm-11:05 pm

1 stop7h 30m

$527

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Fri 11/14

9:11 am-10:53 pm

2 stops11h 42m

Florence

Fri 12/5

10:28 am-5:46 pm

2 stops9h 18m

$532

Colorado SpringsFlorence

COS - FLO

COSFLO

Colorado Springs

Sat 12/13

10:37 am-12:15 am

2 stops11h 38m

Florence

Tue 12/16

11:15 am-8:30 pm

2 stops11h 15m

$555

MontroseFlorence

MTJ - FLO

MTJFLO

Montrose County

Sat 11/15

7:00 am-6:04 pm

2 stops9h 04m

Florence

Tue 11/18

11:14 am-7:19 pm

2 stops10h 05m

$571

Grand JunctionFlorence

GJT - FLO

GJTFLO

Grand Junction Regnl

Wed 12/10

7:30 am-10:53 pm

2 stops13h 23m

Florence

Sat 12/13

11:16 am-8:49 pm

2 stops11h 33m

$571

MontroseFlorence

MTJ - FLO

MTJFLO

Montrose County

Sat 11/15

7:00 am-6:04 pm

2 stops9h 04m

Florence

Tue 11/18

11:14 am-7:19 pm

2 stops10h 05m

$601

MontroseFlorence

MTJ - FLO

MTJFLO

Montrose County

Wed 11/12

7:00 am-10:53 pm

2 stops13h 53m

Florence

Sun 11/16

5:15 am-7:48 pm

2 stops16h 33m

$690

MontroseFlorence

MTJ - FLO

MTJFLO

Montrose County

Wed 11/12

7:00 am-10:53 pm

3 stops13h 53m

Florence

Sun 11/16

5:15 am-7:48 pm

2 stops16h 33m

$804

MontroseFlorence

MTJ - FLO

MTJFLO

Montrose County

Wed 11/12

7:00 am-10:53 pm

3 stops13h 53m

Florence

Sun 11/16

5:15 am-7:48 pm

3 stops16h 33m

$1,010

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Colorado to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Colorado is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $353. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Friday is the most expensive day to depart from Colorado because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $499.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the morning. momondo users have found flights departing from Colorado to Florence, South Carolina in the morning for as low as $429. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the afternoon is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $561 per ticket.

Cheap Colorado to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Colorado to Florence, South Carolina

Direct flights

None
There are no direct flights from Colorado to Florence, South Carolina. There are no popular flight routes from Colorado to Florence, South Carolina.
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  • When did momondo last update prices for flights from Colorado to Florence Airport?

    Prices for flights from Colorado to Florence Airport are updated daily.

  • How many operators does momondo search for flights from Colorado to Florence Airport?

  • How old do you have to be to fly from Colorado to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Colorado to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Colorado to Florence, South Carolina

Compare and see reviews for airlines that fly from Colorado to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $410Free CancellationRating
7.2
11,032 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Colorado to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Colorado.

Can I find flights from Colorado to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Colorado with this policy.

How can momondo help me find flights from Colorado to Florence?

momondo provides multiple filters to help you find the best flight to Florence from Colorado. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Colorado to Florence right now. Can momondo alert me if prices change?

Price alerts on flights to Florence from Colorado are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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