How many flights depart from Cleveland to South Carolina on average per week?

As of October 2026, 6 flights take off from Cleveland and land in South Carolina each week. The most common flight departure day for this route is Mon, with 17% of weekly flights taking off on this day.

What is the cheapest airline that flies from Cleveland Hopkins Intl to South Carolina?

Delta, Southwest, and American Airlines are the most popular carriers operating from Cleveland Hopkins Intl to South Carolina

What airlines fly to South Carolina?

Breeze Airways, Allegiant Air and Delta are the top three most popular airlines that fly to South Carolina from Cleveland according to our data. Breeze Airways is the first choice among our users, with 44% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to South Carolina?

Prices for flights from Cleveland Hopkins Intl Airport to South Carolina are updated daily.

How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to South Carolina?

There are 5 operators available for flights from Cleveland Hopkins Intl Airport to South Carolina as of October 2026.

How old do you have to be to fly from Cleveland Hopkins Intl Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$80 Cheap Flights from Cleveland to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Cleveland to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:59 pm - 8:38 amCLE Cleveland Hopkins Intl-CHS Charleston

10h 39m1 stop Orlando

3:00 pm - 12:27 amCHS Charleston-CLE Cleveland Hopkins Intl

9h 27m1 stop Orlando

$165Multiple Airlines

Mon, Oct 26 - Tue, Oct 27

9:59 pm - 8:38 amCLE Cleveland Hopkins Intl-CHS Charleston

10h 39m1 stop Orlando

3:00 pm - 9:06 amCHS Charleston-CLE Cleveland Hopkins Intl

18h 06m1 stop Orlando

$169Multiple Airlines

Tue, Oct 20 - Tue, Oct 27

5:01 pm - 10:07 pmCLE Cleveland Hopkins Intl-CHS Charleston

5h 06m1 stop Chicago O'Hare Intl

4:16 pm - 8:06 pmCHS Charleston-CLE Cleveland Hopkins Intl

3h 50m1 stop Washington, D.C. Reagan-National

$219American Airlines

Tue, Dec 8 - Sat, Dec 12

4:59 pm - 12:17 amCLE Cleveland Hopkins Intl-CHS Charleston

7h 18m1 stop Chicago O'Hare Intl

8:12 am - 2:04 pmCHS Charleston-CLE Cleveland Hopkins Intl

5h 52m1 stop Charlotte Douglas

$219American Airlines

Sat, Nov 7 - Wed, Nov 11

5:14 pm - 12:04 amCLE Cleveland Hopkins Intl-CHS Charleston

6h 50m1 stop Atlanta Hartsfield-Jackson

5:10 am - 10:31 amCHS Charleston-CLE Cleveland Hopkins Intl

5h 21m1 stop Atlanta Hartsfield-Jackson

$219Delta

Sat, Dec 5 - Tue, Dec 8

3:15 pm - 7:22 pmCLE Cleveland Hopkins Intl-CHS Charleston

4h 07m1 stop Atlanta Hartsfield-Jackson

2:28 pm - 6:49 pmCHS Charleston-CLE Cleveland Hopkins Intl

4h 21m1 stop Atlanta Hartsfield-Jackson

$219Delta

Tue, Dec 8 - Sat, Dec 12

6:00 am - 10:06 amCLE Cleveland Hopkins Intl-CHS Charleston

4h 06m1 stop Washington, D.C. Dulles Intl

7:52 pm - 11:59 pmCHS Charleston-CLE Cleveland Hopkins Intl

4h 07m1 stop Washington, D.C. Dulles Intl

$219United Airlines

Thu, Oct 29 - Mon, Nov 2

6:00 am - 10:06 amCLE Cleveland Hopkins Intl-CHS Charleston

4h 06m1 stop Washington, D.C. Dulles Intl

7:52 pm - 11:59 pmCHS Charleston-CLE Cleveland Hopkins Intl

4h 07m1 stop Washington, D.C. Dulles Intl

$219United Airlines

Thu, Oct 29 - Tue, Nov 3

3:30 pm - 8:10 pmCLE Cleveland Hopkins Intl-CHS Charleston

4h 40m1 stop Baltimore/Washington

8:00 am - 6:25 pmCHS Charleston-CLE Cleveland Hopkins Intl

10h 25m2 stops Chicago Midway Nashville Intl

$224Southwest

Sat, Nov 7 - Wed, Nov 11

6:25 am - 1:15 pmCLE Cleveland Hopkins Intl-CHS Charleston

6h 50m1 stop Nashville Intl

8:00 am - 6:25 pmCHS Charleston-CLE Cleveland Hopkins Intl

10h 25m2 stops Chicago Midway Nashville Intl

$224Southwest

Sat, Dec 5 - Tue, Dec 8

Cheap last minute flights

Enter your travel dates to find the best prices.

6:00 am - 8:38 amCLE Cleveland Hopkins Intl-CHS Charleston

26h 38m1 stop Orlando

3:18 pm - 12:19 amCHS Charleston-CLE Cleveland Hopkins Intl

9h 01m1 stop Orlando

$262Multiple Airlines

Mon, Oct 12 - Tue, Oct 20

9:59 pm - 8:38 amCLE Cleveland Hopkins Intl-CHS Charleston

10h 39m1 stop Orlando

3:00 pm - 12:19 amCHS Charleston-CLE Cleveland Hopkins Intl

9h 19m1 stop Orlando

$292Multiple Airlines

Mon, Oct 12 - Tue, Oct 13

5:43 am - 10:25 amCLE Cleveland Hopkins Intl-HHH Hilton Head Island

4h 42m1 stop Washington, D.C. Reagan-National

6:08 pm - 10:06 pmHHH Hilton Head Island-CLE Cleveland Hopkins Intl

3h 58m1 stop Charlotte Douglas

$399American Airlines

Wed, Oct 14 - Wed, Oct 21

4:36 pm - 11:38 pmCLE Cleveland Hopkins Intl-CAE Columbia Metropolitan

7h 02m1 stop Washington, D.C. Reagan-National

12:31 pm - 4:08 pmCAE Columbia Metropolitan-CLE Cleveland Hopkins Intl

3h 37m1 stop Charlotte Douglas

$399American Airlines

Fri, Oct 16 - Sat, Oct 24

6:10 am - 3:30 pmCLE Cleveland Hopkins Intl-HHH Hilton Head Island

9h 20m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

4:13 pm - 10:10 pmHHH Hilton Head Island-CLE Cleveland Hopkins Intl

5h 57m1 stop New York LaGuardia

$419Delta

Wed, Oct 14 - Wed, Oct 21

1:00 pm - 6:34 pmCLE Cleveland Hopkins Intl-CAE Columbia Metropolitan

5h 34m1 stop Atlanta Hartsfield-Jackson

12:00 pm - 6:34 pmCAE Columbia Metropolitan-CLE Cleveland Hopkins Intl

6h 34m1 stop Atlanta Hartsfield-Jackson

$429Delta

Mon, Oct 12 - Sat, Oct 17

2:40 pm - 10:50 pmCLE Cleveland Hopkins Intl-GSP Greenville

8h 10m2 stops Chicago Midway Nashville Intl

8:05 am - 9:15 pmGSP Greenville-CLE Cleveland Hopkins Intl

13h 10m2 stops Baltimore/Washington Nashville Intl

$504Southwest

Mon, Oct 12 - Tue, Nov 10

2:20 pm - 9:05 pmCLE Cleveland Hopkins Intl-GSP Greenville

6h 45m2 stops Chicago Midway Nashville Intl

1:25 pm - 9:05 pmGSP Greenville-CLE Cleveland Hopkins Intl

7h 40m2 stops Baltimore/Washington Nashville Intl

$536Southwest

Wed, Oct 14 - Wed, Oct 21

5:20 am - 10:27 amCLE Cleveland Hopkins Intl-CHS Charleston

5h 07m1 stop Chicago O'Hare Intl

11:05 am - 6:24 pmCHS Charleston-CLE Cleveland Hopkins Intl

7h 19m1 stop Newark

$619United Airlines

Mon, Oct 12 - Tue, Oct 13

8:00 am - 3:01 pmCLE Cleveland Hopkins Intl-GSP Greenville

7h 01m1 stop Newark

11:30 am - 6:24 pmGSP Greenville-CLE Cleveland Hopkins Intl

6h 54m1 stop Newark

$664United Airlines

Thu, Oct 15 - Wed, Oct 21

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JetBlue flights from Cleveland to South Carolina

Our best JetBlue deals on Cleveland to South Carolina flight tickets

JetBlue

Nov 20

CLE7:00 amCleveland Hopkins Intl

5h 24m

1 stop

CHS12:24 pmCharleston

Nov 23

CHS5:53 pmCharleston

5h 00m

1 stop

CLE10:53 pmCleveland Hopkins Intl

$303

JetBlue

Oct 20

CLE7:00 amCleveland Hopkins Intl

7h 12m

1 stop

CHS2:12 pmCharleston

Oct 24

CHS3:04 pmCharleston

6h 51m

1 stop

CLE9:55 pmCleveland Hopkins Intl

$365

JetBlue

Oct 23

CLE7:00 amCleveland Hopkins Intl

7h 09m

1 stop

CHS2:09 pmCharleston

Oct 24

CHS3:04 pmCharleston

6h 51m

1 stop

CLE9:55 pmCleveland Hopkins Intl

$440

Southwest flights from Cleveland to South Carolina

Our best Southwest deals on Cleveland to South Carolina flight tickets

Southwest

Dec 5

CLE6:25 amCleveland Hopkins Intl

6h 50m

1 stop

CHS1:15 pmCharleston

Dec 8

CHS8:00 amCharleston

10h 25m

2 stops

CLE6:25 pmCleveland Hopkins Intl

$224

Southwest

Dec 5

CLE6:25 amCleveland Hopkins Intl

13h 40m

2 stops

CHS8:05 pmCharleston

Dec 8

CHS8:00 amCharleston

10h 25m

2 stops

CLE6:25 pmCleveland Hopkins Intl

$235

Southwest

Nov 3

CLE3:50 pmCleveland Hopkins Intl

4h 00m

1 stop

GSP7:50 pmGreenville

Nov 10

GSP8:05 amGreenville

3h 55m

1 stop

CLE12:00 pmCleveland Hopkins Intl

$246

momondo Fare Finder

Use the filters below to find and compare flights from Cleveland to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Mon 10/26

9:59 pm-8:38 am

1 stop10h 39m

Charleston

Tue 10/27

3:00 pm-12:27 am

1 stop9h 27m

$165

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Tue 10/20

9:59 pm-8:38 am

1 stop10h 39m

Charleston

Tue 10/27

3:00 pm-9:06 am

1 stop18h 06m

$169

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Tue 12/8

5:01 pm-10:07 pm

1 stop5h 06m

Charleston

Sat 12/12

4:16 pm-8:06 pm

1 stop3h 50m

$219

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Sat 11/7

4:59 pm-12:17 am

1 stop7h 18m

Charleston

Wed 11/11

8:12 am-2:04 pm

1 stop5h 52m

$219

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Sat 12/5

5:14 pm-12:04 am

1 stop6h 50m

Charleston

Tue 12/8

5:10 am-10:31 am

1 stop5h 21m

$219

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Tue 12/8

3:15 pm-7:22 pm

1 stop4h 07m

Charleston

Sat 12/12

2:28 pm-6:49 pm

1 stop4h 21m

$219

Quickest round-trip

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Thu 10/29

6:00 am-10:06 am

1 stop4h 06m

Charleston

Mon 11/2

7:52 pm-11:59 pm

1 stop4h 07m

$219

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Thu 10/29

6:00 am-10:06 am

1 stop4h 06m

Charleston

Tue 11/3

7:52 pm-11:59 pm

1 stop4h 07m

$219

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Sat 11/7

3:30 pm-8:10 pm

1 stop4h 40m

Charleston

Wed 11/11

8:00 am-6:25 pm

2 stops10h 25m

$224

ClevelandCharleston

CLE Cleveland Hopkins Intl - CHS Charleston

CLECHS

Cleveland Hopkins Intl

Sat 12/5

6:25 am-1:15 pm

1 stop6h 50m

Charleston

Tue 12/8

8:00 am-6:25 pm

2 stops10h 25m

$224

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Cleveland to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Cleveland is in August. Flight prices, which tend to average around $304, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Cleveland during April instead. Flights to South Carolina in April, while not as cheap as those in August, still average around $316.

What is the cheapest Cleveland Hopkins Intl to South Carolina flight route?

Fly from Cleveland Hopkins Intl to Myrtle Beach Intl for the best Cleveland Hopkins Intl - South Carolina flight prices

How far in advance should I book a flight from Cleveland to South Carolina?

You are more likely to see cheaper flights to South Carolina from Cleveland when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $383 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Cleveland for as low as $288 on momondo.

What cabin class options are available on Cleveland to South Carolina flights?

There are 3 cabin classes available to choose from on Cleveland to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cleveland to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Cleveland to South Carolina.

Cheap Cleveland to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to South Carolina

Best Price Found	$80
Fastest flight time	1h 43m
Direct flights	None

The best one-way flight to South Carolina from Cleveland in the past 72 hours is $80. The best round-trip flight deal from Cleveland to South Carolina found on momondo in the last 72 hours is $165.

The fastest flight from Cleveland to South Carolina takes 1h 43m

There are no direct flights from Cleveland to South Carolina. There are no popular flight routes from Cleveland to South Carolina.

Search flight deals

Frequently asked questions about flying from Cleveland to South Carolina

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to South Carolina?
Prices for flights from Cleveland Hopkins Intl Airport to South Carolina are updated daily.
How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to South Carolina?
There are 5 operators available for flights from Cleveland Hopkins Intl Airport to South Carolina as of October 2026.
How old do you have to be to fly from Cleveland Hopkins Intl Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Cleveland to South Carolina?
momondo data reveals that the most frequently booked plane model on the route from Cleveland to South Carolina is Airbus A320neo, representing 36.57% of all bookings. The subsequent popular models are Airbus A319 at 27.31%, Airbus A321neo at 14.35%, and Airbus A220-300 at 8.33%.

Best airlines flying from Cleveland to South Carolina

Compare and see reviews for airlines that fly from Cleveland to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $81	Free Cancellation	Rating 5.6 2,551 reviews	Search Frontier flights
Delta	PriceFrom $128	Free Cancellation	Rating 7.8 8,646 reviews	Search Delta flights
United Airlines	PriceFrom $169	Free Cancellation	Rating 7.4 10,322 reviews	Search United Airlines flights
American Airlines	PriceFrom $210	Free Cancellation	Rating 7.0 12,146 reviews	Search American Airlines flights
Southwest	PriceFrom $233	Free Cancellation	Rating 7.9 4,224 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Cleveland to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Cleveland to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Cleveland to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Cleveland to South Carolina?

Once all potential Cleveland to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Cleveland to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Cleveland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.