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Cheap flights from Cleveland to Knoxville from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Knoxville departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Cleveland to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:20 pm - 3:57 pmCLE-TYS
19h 37m1 stop
Multiple Airlines Logo
9:08 am - 10:53 pmTYS-CLE
13h 45m1 stop
$197Multiple Airlines
Find Deal
Sun, Dec 14 - Thu, Dec 18
Multiple Airlines Logo
8:20 pm - 3:57 pmCLE-TYS
19h 37m1 stop
Multiple Airlines Logo
9:25 pm - 10:37 amTYS-CLE
13h 12m1 stop
$200Multiple Airlines
Find Deal
Sun, Dec 14 - Fri, Dec 19
Multiple Airlines Logo
7:17 pm - 4:02 pmCLE-TYS
20h 45m1 stop
Multiple Airlines Logo
9:08 am - 10:53 pmTYS-CLE
13h 45m1 stop
$212Multiple Airlines
Find Deal
Mon, Dec 15 - Thu, Dec 18
Multiple Airlines Logo
6:45 am - 8:33 amCLE-TYS
25h 48m1 stop
Multiple Airlines Logo
4:52 pm - 11:07 amTYS-CLE
18h 15m1 stop
$221Multiple Airlines
Find Deal
Sun, Dec 14 - Mon, Dec 15
Multiple Airlines Logo
10:54 am - 8:33 amCLE-TYS
21h 39m1 stop
Multiple Airlines Logo
4:52 pm - 11:07 amTYS-CLE
18h 15m1 stop
$235Multiple Airlines
Find Deal
Thu, Dec 11 - Mon, Dec 15
Multiple Airlines Logo
7:14 am - 9:37 pmCLE-TYS
14h 23m2 stops
Multiple Airlines Logo
4:52 pm - 11:07 amTYS-CLE
18h 15m1 stop
$242Multiple Airlines
Find Deal
Thu, Dec 11 - Mon, Dec 15
Multiple Airlines Logo
8:58 am - 5:20 pmCLE-TYS
8h 22m1 stop
Multiple Airlines Logo
9:08 am - 10:53 pmTYS-CLE
13h 45m1 stop
$244Multiple Airlines
Find Deal
Mon, Dec 15 - Thu, Dec 18
Multiple Airlines Logo
6:00 am - 10:42 pmCLE-TYS
16h 42m2 stops
Multiple Airlines Logo
9:08 am - 10:53 pmTYS-CLE
13h 45m1 stop
$256Multiple Airlines
Find Deal
Sun, Dec 14 - Thu, Dec 18
Multiple Airlines Logo
7:17 pm - 9:44 pmCLE-TYS
26h 27m1 stop
Multiple Airlines Logo
12:53 pm - 9:49 amTYS-CLE
20h 56m1 stop
$259Multiple Airlines
Find Deal
Wed, Dec 3 - Sat, Dec 6
Multiple Airlines Logo
5:30 am - 9:34 pmCLE-TYS
16h 04m1 stop
Multiple Airlines Logo
9:45 am - 10:13 amTYS-CLE
24h 28m1 stop
$260Multiple Airlines
Find Deal
Sat, Dec 20 - Thu, Dec 25

Delta flights from Cleveland to Knoxville

Our best Delta deals on Cleveland to Knoxville flight tickets
Delta
Apr 24
CLE7:40 pmCleveland Hopkins Intl
4h 06m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
Apr 29
TYS7:30 amKnoxville McGhee Tyson
6h 04m
1 stop
CLE1:34 pmCleveland Hopkins Intl
$292
Find similar
Delta
Apr 23
CLE2:05 pmCleveland Hopkins Intl
3h 22m
1 stop
TYS5:27 pmKnoxville McGhee Tyson
Apr 29
TYS11:30 amKnoxville McGhee Tyson
3h 40m
1 stop
CLE3:10 pmCleveland Hopkins Intl
$307
Find similar
Delta
Apr 24
CLE7:40 pmCleveland Hopkins Intl
4h 06m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
Apr 26
TYS5:15 pmKnoxville McGhee Tyson
6h 29m
1 stop
CLE11:44 pmCleveland Hopkins Intl
$317
Find similar

Southwest flights from Cleveland to Knoxville

Our best Southwest deals on Cleveland to Knoxville flight tickets
Southwest
May 12
CLE6:40 amCleveland Hopkins Intl
5h 20m
1 stop
TYS12:00 pmKnoxville McGhee Tyson
May 14
TYS8:05 amKnoxville McGhee Tyson
3h 55m
1 stop
CLE12:00 pmCleveland Hopkins Intl
$302
Find similar
Southwest
May 12
CLE4:20 pmCleveland Hopkins Intl
4h 30m
1 stop
TYS8:50 pmKnoxville McGhee Tyson
May 14
TYS12:15 pmKnoxville McGhee Tyson
11h 05m
2 stops
CLE11:20 pmCleveland Hopkins Intl
$303
Find similar
Southwest
May 12
CLE5:50 amCleveland Hopkins Intl
11h 15m
2 stops
TYS5:05 pmKnoxville McGhee Tyson
May 14
TYS12:15 pmKnoxville McGhee Tyson
11h 05m
2 stops
CLE11:20 pmCleveland Hopkins Intl
$308
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Cleveland to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sun 12/14

8:20 pm-3:57 pm

1 stop19h 37m

Knoxville McGhee Tyson

Thu 12/18

9:08 am-10:53 pm

1 stop13h 45m

$197

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sun 12/14

8:20 pm-3:57 pm

1 stop19h 37m

Knoxville McGhee Tyson

Fri 12/19

9:25 pm-10:37 am

1 stop13h 12m

$200

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Mon 12/15

7:17 pm-4:02 pm

1 stop20h 45m

Knoxville McGhee Tyson

Thu 12/18

9:08 am-10:53 pm

1 stop13h 45m

$212

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sun 12/14

6:45 am-8:33 am

1 stop25h 48m

Knoxville McGhee Tyson

Mon 12/15

4:52 pm-11:07 am

1 stop18h 15m

$221

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Thu 12/11

10:54 am-8:33 am

1 stop21h 39m

Knoxville McGhee Tyson

Mon 12/15

4:52 pm-11:07 am

1 stop18h 15m

$235

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Thu 12/11

7:14 am-9:37 pm

2 stops14h 23m

Knoxville McGhee Tyson

Mon 12/15

4:52 pm-11:07 am

1 stop18h 15m

$242

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Mon 12/15

8:58 am-5:20 pm

1 stop8h 22m

Knoxville McGhee Tyson

Thu 12/18

9:08 am-10:53 pm

1 stop13h 45m

$244

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sun 12/14

6:00 am-10:42 pm

2 stops16h 42m

Knoxville McGhee Tyson

Thu 12/18

9:08 am-10:53 pm

1 stop13h 45m

$256

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Wed 12/3

7:17 pm-9:44 pm

1 stop26h 27m

Knoxville McGhee Tyson

Sat 12/6

12:53 pm-9:49 am

1 stop20h 56m

$259

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sat 12/20

5:30 am-9:34 pm

1 stop16h 04m

Knoxville McGhee Tyson

Thu 12/25

9:45 am-10:13 am

1 stop24h 28m

$260

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Cleveland to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Cleveland, with most prices found around $238. If you aren’t able to travel during the month of February, then book flights to Knoxville from Cleveland during September instead. Flights to Knoxville in September, while not as cheap as those in February, still average around $268.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Cleveland to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $258. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Cleveland to Knoxville for around $418.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Cleveland to Knoxville when you can find flight prices for as low as $264. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $392.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Cleveland when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $316 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Cleveland for as low as $236 on momondo.

How have Cleveland to Knoxville flight prices changed over time?

As of November 2025, prices for Cleveland to Knoxville flights are approximately 64% more expensive when compared to flights at the same time last year.

When to book flights from Cleveland to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Cleveland to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cleveland to Knoxville (CLE to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Knoxville

Direct flights

None
There are no direct flights from Cleveland to Knoxville. There are no popular flight routes from Cleveland to Knoxville.
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  • How far is Cleveland Hopkins Intl to Knoxville McGhee Tyson by plane?

    The distance between Cleveland Hopkins Intl and Knoxville McGhee Tyson is about 400.8 mi. Typically, this will take 3h 22m by plane in normal conditions.

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Cleveland Hopkins Intl Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cleveland Hopkins Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Cleveland to Knoxville?

Best airlines flying from Cleveland to Knoxville

Compare and see reviews for airlines that fly from Cleveland to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $205Free CancellationRating
7.4
9,037 reviews
Search United Airlines flights
American AirlinesPriceFrom $218Free CancellationRating
7.2
11,046 reviews
Search American Airlines flights
DeltaPriceFrom $222Free CancellationRating
7.9
7,997 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Cleveland to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Cleveland to Knoxville with flexible booking policies on momondo?

Flights from Cleveland to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Cleveland to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Cleveland. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Cleveland to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Cleveland to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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