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Cheap flights from Cleveland to Des Moines from $116

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Des Moines departing on 8/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Cleveland to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 10:18 am
CLE
-
DSM
5h 18m
1 stop
Delta Logo
6:35 pm - 12:29 am
DSM
-
CLE
4h 54m
1 stop
$231Delta
Sat, Aug 8 - Mon, Aug 10
United Airlines Logo
6:00 am - 10:17 am
CLE
-
DSM
5h 17m
1 stop
United Airlines Logo
6:00 am - 11:41 am
DSM
-
CLE
4h 41m
1 stop
$247United Airlines
Thu, Aug 6 - Sat, Aug 8
Southwest Logo
4:35 pm - 7:25 pm
CLE
-
DSM
3h 50m
1 stop
Southwest Logo
5:40 am - 4:45 pm
DSM
-
CLE
10h 05m
2 stops
$253Southwest
Sat, Aug 8 - Mon, Aug 10
Delta Logo
4:00 pm - 8:46 pm
CLE
-
DSM
5h 46m
1 stop
Delta Logo
2:34 pm - 10:18 pm
DSM
-
CLE
6h 44m
1 stop
$261Delta
Fri, Sep 18 - Tue, Sep 22
United Airlines Logo
3:06 pm - 9:23 pm
CLE
-
DSM
7h 17m
2 stops
United Airlines Logo
6:00 am - 11:16 am
DSM
-
CLE
4h 16m
1 stop
$266United Airlines
Fri, Aug 28 - Wed, Sep 2
Multiple Airlines Logo
5:15 pm - 7:54 pm
CLE
-
DSM
27h 39m
2 stops
Multiple Airlines Logo
2:19 pm - 3:47 pm
DSM
-
CLE
24h 28m
1 stop
$271Multiple Airlines
Wed, Aug 19 - Mon, Aug 24
United Airlines Logo
6:00 am - 10:17 am
CLE
-
DSM
5h 17m
1 stop
United Airlines Logo
6:00 am - 2:06 pm
DSM
-
CLE
7h 06m
2 stops
$277United Airlines
Thu, Aug 6 - Sat, Aug 8
Southwest Logo
4:00 pm - 9:55 pm
CLE
-
DSM
6h 55m
1 stop
Southwest Logo
5:10 am - 12:55 pm
DSM
-
CLE
6h 45m
2 stops
$281Southwest
Fri, Oct 9 - Mon, Oct 12
Southwest Logo
4:50 pm - 10:55 pm
CLE
-
DSM
7h 05m
2 stops
Southwest Logo
5:10 am - 12:55 pm
DSM
-
CLE
6h 45m
2 stops
$286Southwest
Fri, Oct 9 - Mon, Oct 12
Southwest Logo
11:00 am - 10:10 pm
CLE
-
DSM
12h 10m
2 stops
Southwest Logo
6:10 am - 5:00 pm
DSM
-
CLE
9h 50m
2 stops
$291Southwest
Fri, Aug 28 - Wed, Sep 2

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Delta flights from Cleveland to Des Moines

Our best Delta deals on Cleveland to Des Moines flight tickets
Delta
Aug 8
CLE6:00 amCleveland Hopkins Intl
5h 18m
1 stop
DSM10:18 amDes Moines
Aug 10
DSM6:35 pmDes Moines
4h 54m
1 stop
CLE12:29 amCleveland Hopkins Intl
$231
Delta
Sep 18
CLE4:00 pmCleveland Hopkins Intl
5h 46m
1 stop
DSM8:46 pmDes Moines
Sep 22
DSM2:34 pmDes Moines
6h 44m
1 stop
CLE10:18 pmCleveland Hopkins Intl
$261
Delta
Aug 19
CLE10:52 amCleveland Hopkins Intl
4h 12m
1 stop
DSM2:04 pmDes Moines
Aug 24
DSM5:30 pmDes Moines
5h 26m
1 stop
CLE11:56 pmCleveland Hopkins Intl
$303

United Airlines flights from Cleveland to Des Moines

Our best United Airlines deals on Cleveland to Des Moines flight tickets
United Airlines
Aug 6
CLE6:00 amCleveland Hopkins Intl
5h 17m
1 stop
DSM10:17 amDes Moines
Aug 8
DSM6:00 amDes Moines
4h 41m
1 stop
CLE11:41 amCleveland Hopkins Intl
$247
United Airlines
Aug 28
CLE3:06 pmCleveland Hopkins Intl
7h 17m
2 stops
DSM9:23 pmDes Moines
Sep 2
DSM6:00 amDes Moines
4h 16m
1 stop
CLE11:16 amCleveland Hopkins Intl
$266
United Airlines
Aug 6
CLE6:00 amCleveland Hopkins Intl
5h 17m
1 stop
DSM10:17 amDes Moines
Aug 8
DSM6:00 amDes Moines
7h 06m
2 stops
CLE2:06 pmCleveland Hopkins Intl
$277

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from Cleveland to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Sat 8/8

6:00 am-10:18 am

1 stop5h 18m

Des Moines

Mon 8/10

6:35 pm-12:29 am

1 stop4h 54m

$231
Quickest round-trip

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Thu 8/6

6:00 am-10:17 am

1 stop5h 17m

Des Moines

Sat 8/8

6:00 am-11:41 am

1 stop4h 41m

$247

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Sat 8/8

4:35 pm-7:25 pm

1 stop3h 50m

Des Moines

Mon 8/10

5:40 am-4:45 pm

2 stops10h 05m

$253

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Fri 9/18

4:00 pm-8:46 pm

1 stop5h 46m

Des Moines

Tue 9/22

2:34 pm-10:18 pm

1 stop6h 44m

$261

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Fri 8/28

3:06 pm-9:23 pm

2 stops7h 17m

Des Moines

Wed 9/2

6:00 am-11:16 am

1 stop4h 16m

$266

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Wed 8/19

5:15 pm-7:54 pm

2 stops27h 39m

Des Moines

Mon 8/24

2:19 pm-3:47 pm

1 stop24h 28m

$271

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Thu 8/6

6:00 am-10:17 am

1 stop5h 17m

Des Moines

Sat 8/8

6:00 am-2:06 pm

2 stops7h 06m

$277

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Fri 10/9

4:00 pm-9:55 pm

1 stop6h 55m

Des Moines

Mon 10/12

5:10 am-12:55 pm

2 stops6h 45m

$281

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Fri 10/9

4:50 pm-10:55 pm

2 stops7h 05m

Des Moines

Mon 10/12

5:10 am-12:55 pm

2 stops6h 45m

$286

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Fri 8/28

11:00 am-10:10 pm

2 stops12h 10m

Des Moines

Wed 9/2

6:10 am-5:00 pm

2 stops9h 50m

$291

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Cleveland to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Cleveland and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then September is your next best option. Flight prices from Cleveland to Des Moines during September average around $326.

How have Cleveland to Des Moines flight prices changed over time?

When to book flights from Cleveland to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Cleveland to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cleveland to Des Moines (CLE to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Des Moines

Fastest flight time

3h 47m

Direct flights

None
The fastest flight from Cleveland to Des Moines takes 3h 47m
There are no direct flights from Cleveland to Des Moines. There are no popular flight routes from Cleveland to Des Moines.
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Frequently asked questions about flying from Cleveland to Des Moines

  • How far is Cleveland Hopkins Intl to Des Moines by plane?

    The distance between Cleveland Hopkins Intl and Des Moines is about 616.3 mi. In terms of flight time, this usually takes a little over 3h 47m.

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Des Moines Airport?

    Prices for flights from Cleveland Hopkins Intl Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Des Moines Airport?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Cleveland to Des Moines?

Best airlines flying from Cleveland to Des Moines

Compare and see reviews for airlines that fly from Cleveland to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $236Free CancellationRating
7.1
11,811 reviews
Search American Airlines flights
DeltaPriceFrom $280Free CancellationRating
7.8
8,462 reviews
Search Delta flights
United AirlinesPriceFrom $306Free CancellationRating
7.4
9,983 reviews
Search United Airlines flights
SouthwestPriceFrom $319Free CancellationRating
8.0
4,249 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Osceola
Johnston
Newton
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Des Moines?

Finding the right flight to Des Moines from Cleveland is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Cleveland to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Cleveland on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Cleveland to Des Moines?

Once all potential Cleveland to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Cleveland to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Cleveland to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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