What is the cheapest airline that flies from Chicago to South Carolina?

Spirit Airlines, Frontier, and Southwest are the most popular carriers operating from Chicago to South Carolina

How many flights depart from Chicago to South Carolina on average per week?

451 flights are operational weekly from Chicago to South Carolina as of August 2025. The most popular departure day for this route is Wed, with 21% of flights per week taking off on this day.

What airlines fly to South Carolina?

American Airlines, United Airlines and Spirit Airlines are the top three most popular airlines that fly to South Carolina from Chicago according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Chicago to South Carolina on average per day?

As of August 2025, there are 64 flights per day flying from Chicago to South Carolina. The most common time of day flights depart is 6:00PM, with 34% of flights taking off at noon.

When did momondo last update prices for flights from Chicago to South Carolina?

Prices for flights from Chicago to South Carolina were last updated today.

How many operators does momondo search for flights from Chicago to South Carolina?

The number of operators available for flights from Chicago to South Carolina is 7 as of August 2025.

How old do you have to be to fly from Chicago to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$44 Cheap Flights from Chicago to South Carolina in 2025

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Find the cheapest flights from Chicago to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

7:40 am - 11:00 amORD-CLT

2h 20mnonstop

11:50 am - 1:12 pmCLT-ORD

2h 22mnonstop

$85Frontier

Find Deal

jue., sep. 11 - dom., sep. 14

7:40 am - 11:00 amORD-CLT

2h 20mnonstop

11:50 am - 1:12 pmCLT-ORD

2h 22mnonstop

$97Frontier

Find Deal

jue., sep. 4 - jue., sep. 11

10:12 am - 1:13 pmORD-MYR

2h 01mnonstop

2:18 pm - 3:43 pmMYR-ORD

2h 25mnonstop

$98Spirit Airlines

Find Deal

jue., ago. 21 - jue., ago. 28

10:12 am - 1:13 pmORD-MYR

2h 01mnonstop

2:18 pm - 3:43 pmMYR-ORD

2h 25mnonstop

$100Spirit Airlines

Find Deal

jue., ago. 28 - dom., ago. 31

6:05 pm - 9:15 pmMDW-CHS

2h 10mnonstop

6:35 am - 7:40 amCHS-MDW

2h 05mnonstop

$121Southwest

Find Deal

mié., ago. 27 - mié., sep. 3

7:10 am - 10:24 amORD-CLT

2h 14mnonstop

5:30 pm - 6:55 pmCLT-ORD

2h 25mnonstop

$123United Airlines

Find Deal

mar., sep. 2 - mar., sep. 9

1:05 pm - 4:00 pmMDW-CLT

1h 55mnonstop

5:20 pm - 6:20 pmCLT-MDW

2h 00mnonstop

$123Southwest

Find Deal

mié., sep. 3 - sáb., sep. 6

7:35 am - 10:43 amORD-CLT

2h 08mnonstop

7:21 pm - 8:27 pmCLT-ORD

2h 06mnonstop

$124American Airlines

Find Deal

mar., sep. 2 - mar., sep. 9

7:10 am - 10:26 amORD-CLT

2h 16mnonstop

10:35 am - 11:46 amCLT-ORD

2h 11mnonstop

$125United Airlines

Find Deal

jue., ago. 28 - mar., sep. 2

8:47 pm - 11:53 pmORD-CLT

2h 06mnonstop

3:30 pm - 4:45 pmCLT-ORD

2h 15mnonstop

$136American Airlines

Find Deal

vie., sep. 12 - lun., sep. 15

Frontier flights from Chicago to South Carolina

Our best Frontier deals on Chicago to South Carolina flight tickets

Frontier

Sep 11

ORD7:40 amChicago O'Hare Intl

2h 20m

CLT11:00 amCharlotte Douglas

Sep 14

CLT11:50 amCharlotte Douglas

2h 22m

ORD1:12 pmChicago O'Hare Intl

$85

Find similar

Frontier

Sep 4

ORD7:40 amChicago O'Hare Intl

2h 20m

CLT11:00 amCharlotte Douglas

Sep 11

CLT11:50 amCharlotte Douglas

2h 22m

ORD1:12 pmChicago O'Hare Intl

$97

Find similar

Frontier

Sep 25

ORD7:40 amChicago O'Hare Intl

2h 20m

CLT11:00 amCharlotte Douglas

Sep 29

CLT11:50 amCharlotte Douglas

2h 22m

ORD1:12 pmChicago O'Hare Intl

$98

Find similar

American Airlines flights from Chicago to South Carolina

Our best American Airlines deals on Chicago to South Carolina flight tickets

American Airlines

Sep 2

ORD7:35 amChicago O'Hare Intl

2h 08m

CLT10:43 amCharlotte Douglas

Sep 9

CLT7:21 pmCharlotte Douglas

2h 06m

ORD8:27 pmChicago O'Hare Intl

$124

Find similar

American Airlines

Sep 12

ORD8:47 pmChicago O'Hare Intl

2h 06m

CLT11:53 pmCharlotte Douglas

Sep 15

CLT3:30 pmCharlotte Douglas

2h 15m

ORD4:45 pmChicago O'Hare Intl

$136

Find similar

American Airlines

Oct 18

ORD8:17 amChicago O'Hare Intl

2h 12m

SAV11:29 amSavannah/Hilton Head

Oct 25

SAV12:09 pmSavannah/Hilton Head

2h 36m

ORD1:45 pmChicago O'Hare Intl

$139

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 9/11

7:40 am-11:00 am

Nonstop2h 20m

Charlotte Douglas

dom. 9/14

11:50 am-1:12 pm

Nonstop2h 22m

$85

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 9/4

7:40 am-11:00 am

Nonstop2h 20m

Charlotte Douglas

jue. 9/11

11:50 am-1:12 pm

Nonstop2h 22m

$97

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

jue. 8/21

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

jue. 8/28

2:18 pm-3:43 pm

Nonstop2h 25m

$98

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

jue. 8/28

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

dom. 8/31

2:18 pm-3:43 pm

Nonstop2h 25m

$100

ChicagoCharleston

MDW - CHS

MDWCHS

Chicago Midway

mié. 8/27

6:05 pm-9:15 pm

Nonstop2h 10m

Charleston

mié. 9/3

6:35 am-7:40 am

Nonstop2h 05m

$121

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

mar. 9/2

7:10 am-10:24 am

Nonstop2h 14m

Charlotte Douglas

mar. 9/9

5:30 pm-6:55 pm

Nonstop2h 25m

$123

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mié. 9/3

1:05 pm-4:00 pm

Nonstop1h 55m

Charlotte Douglas

sáb. 9/6

5:20 pm-6:20 pm

Nonstop2h 00m

$123

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

mar. 9/2

7:35 am-10:43 am

Nonstop2h 08m

Charlotte Douglas

mar. 9/9

7:21 pm-8:27 pm

Nonstop2h 06m

$124

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 8/28

7:10 am-10:26 am

Nonstop2h 16m

Charlotte Douglas

mar. 9/2

10:35 am-11:46 am

Nonstop2h 11m

$125

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

vie. 9/12

8:47 pm-11:53 pm

Nonstop2h 06m

Charlotte Douglas

lun. 9/15

3:30 pm-4:45 pm

Nonstop2h 15m

$136

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How to get the cheapest flight ticket from Chicago to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Chicago is in August. Flight prices, which tend to average around $343, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Chicago during September instead. Flights to South Carolina in September, while not as cheap as those in August, still average around $352.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $363. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $429.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Chicago to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $349. Try not to purchase tickets in the afternoon because they tend to be around $410. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to South Carolina flight route?

Fly from Chicago O'Hare Intl to Myrtle Beach Intl for the best Chicago - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $381 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Chicago for as low as $317 on momondo.

What cabin class options are available on Chicago to South Carolina flights?

There are 4 cabin classes available to choose from on Chicago to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Chicago to South Carolina.

Cheap Chicago to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South Carolina

Best Price Found	$44
Fastest flight time	1h 46m
Direct flights	Every day
Airports in South Carolina	5 airports

The best one-way flight to South Carolina from Chicago in the past 72 hours is $44. The best round-trip flight deal from Chicago to South Carolina found on momondo in the last 72 hours is $85.

The fastest flight from Chicago to South Carolina takes 1h 46m

Direct flights go from Chicago to South Carolina every day.

There are 5 airports near South Carolina: Greenville (GSP), Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS)

Search flight deals

When did momondo last update prices for flights from Chicago to South Carolina?
Prices for flights from Chicago to South Carolina were last updated today.
How many operators does momondo search for flights from Chicago to South Carolina?
The number of operators available for flights from Chicago to South Carolina is 7 as of August 2025.
How old do you have to be to fly from Chicago to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Chicago to South Carolina?
Based on momondo bookings for flights between Chicago and South Carolina, the leading plane model is Embraer 175, making up 19.86% of the total bookings. Other popular models include Embraer 175 (Enhanced Winglets) with 11.77%, Embraer 170 with 11.53%, and Boeing 737-700 with 11.09%.

Best airlines flying from Chicago to South Carolina

Compare and see reviews for airlines that fly from Chicago to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $55	Free Cancellation	Rating 6.3 8,055 reviews	Search Spirit Airlines flights
Delta	PriceFrom $149	Free Cancellation	Rating 8.0 7,985 reviews	Search Delta flights
United Airlines	PriceFrom $167	Free Cancellation	Rating 7.4 8,917 reviews	Search United Airlines flights
American Airlines	PriceFrom $188	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Southwest	PriceFrom $216	Free Cancellation	Rating 8.0 4,247 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to South Carolina for you.

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South Carolina?

Once you have performed a search for Chicago to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Chicago and alert you when they change.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

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Find better results for your trip to South Carolina

Popular cities in South Carolina

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Cheap flights from Chicago to South Carolina from $44

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to South Carolina departing on 9/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Chicago to South Carolina

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Frontier flights from Chicago to South Carolina

Our best Frontier deals on Chicago to South Carolina flight tickets

American Airlines flights from Chicago to South Carolina

Our best American Airlines deals on Chicago to South Carolina flight tickets

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Use the filters below to find and compare flights from Chicago to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Chicago to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $363. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $429.

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Chicago to South Carolina flight route?

Fly from Chicago O'Hare Intl to Myrtle Beach Intl for the best Chicago - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

What cabin class options are available on Chicago to South Carolina flights?

There are 4 cabin classes available to choose from on Chicago to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Chicago to South Carolina.

What is the cheapest airline that flies from Chicago to South Carolina?

Spirit Airlines, Frontier, and Southwest are the most popular carriers operating from Chicago to South Carolina

What airlines fly to South Carolina?

How many flights depart from Chicago to South Carolina on average per day?

As of August 2025, there are 64 flights per day flying from Chicago to South Carolina. The most common time of day flights depart is 6:00PM, with 34% of flights taking off at noon.

How many flights depart from Chicago to South Carolina on average per week?

451 flights are operational weekly from Chicago to South Carolina as of August 2025. The most popular departure day for this route is Wed, with 21% of flights per week taking off on this day.

Cheap Chicago to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

When did momondo last update prices for flights from Chicago to South Carolina?

How many operators does momondo search for flights from Chicago to South Carolina?

How old do you have to be to fly from Chicago to South Carolina?

What documentation or ID do you need to fly to South Carolina?

What is the most popular plane model from Chicago to South Carolina?

Best airlines flying from Chicago to South Carolina

Compare and see reviews for airlines that fly from Chicago to South Carolina with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

How can momondo help me find flights from Chicago to South Carolina?

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo