How many flights depart from Chicago to South Carolina on average per week?

520 flights are operational weekly from Chicago to South Carolina as of March 2026. The most popular departure day for this route is Mon, with 20% of flights per week taking off on this day.

What airlines fly to South Carolina?

American Airlines, United Airlines and Spirit Airlines are the top three most popular airlines that fly to South Carolina from Chicago according to our data. American Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Chicago to South Carolina on average per day?

As of March 2026, there are 74 flights per day flying from Chicago to South Carolina. The most common time of day flights depart is 5:00PM, with 45% of flights taking off in the afternoon.

What is the cheapest airline that flies from Chicago to South Carolina?

Southwest, Spirit Airlines, and Delta are the most popular carriers operating from Chicago to South Carolina

When did momondo last update prices for flights from Chicago to South Carolina?

Prices for flights from Chicago to South Carolina were last updated today.

How many operators does momondo search for flights from Chicago to South Carolina?

The number of operators available for flights from Chicago to South Carolina is 7 as of March 2026.

How old do you have to be to fly from Chicago to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$68 Cheap Flights from Chicago to South Carolina in 2026

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Find the cheapest flights from Chicago to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:12 pm - 4:22 pm

ORD

CLT

2h 10mnonstop

4:19 pm - 5:53 pm

CLT

ORD

2h 34mnonstop

$112Frontier

Mon, Apr 20 - Thu, Apr 23

12:37 pm - 3:45 pm

ORD

CLT

2h 08mnonstop

4:19 pm - 5:53 pm

CLT

ORD

2h 34mnonstop

$113Frontier

Mon, Apr 27 - Thu, Apr 30

6:00 pm - 8:55 pm

MDW

CLT

1h 55mnonstop

6:20 pm - 7:25 pm

CLT

MDW

2h 05mnonstop

$167Southwest

Tue, Apr 21 - Tue, Apr 28

3:00 pm - 9:40 pm

MDW

CLT

5h 40m

1 stop

6:20 pm - 7:25 pm

CLT

MDW

2h 05mnonstop

$177Southwest

Tue, Apr 21 - Tue, Apr 28

5:45 pm - 8:47 pm

ORD

GSP

2h 02mnonstop

10:36 am - 11:53 am

GSP

ORD

2h 17mnonstop

$249United Airlines

Tue, Apr 14 - Tue, Apr 28

8:00 am - 11:01 am

ORD

GSP

2h 01mnonstop

7:30 am - 8:56 am

GSP

ORD

2h 26mnonstop

$252American Airlines

Wed, Apr 15 - Sat, Apr 18

7:59 pm - 11:02 pm

ORD

GSP

2h 03mnonstop

8:14 pm - 9:36 pm

GSP

ORD

2h 22mnonstop

$255American Airlines

Sat, May 16 - Tue, May 19

8:45 am - 2:12 pm

ORD

GSP

4h 27m

1 stop

6:30 am - 7:54 am

GSP

ORD

2h 24mnonstop

$259United Airlines

Tue, Apr 14 - Tue, Apr 28

5:05 am - 7:33 pm

ORD

MYR

13h 28m

1 stop

11:52 am - 9:31 am

MYR

ORD

22h 39m

1 stop

$274Spirit Airlines

Wed, May 20 - Sat, May 23

11:51 am - 8:58 pm

ORD

MYR

8h 07m

2 stops

11:52 am - 10:46 am

MYR

ORD

23h 54m

2 stops

$275Spirit Airlines

Thu, May 14 - Mon, May 18

Frontier flights from Chicago to South Carolina

Our best Frontier deals on Chicago to South Carolina flight tickets

Frontier

Apr 20

ORD1:12 pmChicago O'Hare Intl

2h 10m

CLT4:22 pmCharlotte Douglas

Apr 23

CLT4:19 pmCharlotte Douglas

2h 34m

ORD5:53 pmChicago O'Hare Intl

$112

Frontier

Apr 27

ORD12:37 pmChicago O'Hare Intl

2h 08m

CLT3:45 pmCharlotte Douglas

Apr 30

CLT4:19 pmCharlotte Douglas

2h 34m

ORD5:53 pmChicago O'Hare Intl

$113

Frontier

Apr 24

ORD12:37 pmChicago O'Hare Intl

2h 08m

CLT3:45 pmCharlotte Douglas

Apr 26

CLT10:39 pmCharlotte Douglas

26h 19m

1 stop

ORD11:58 pmChicago O'Hare Intl

$114

Southwest flights from Chicago to South Carolina

Our best Southwest deals on Chicago to South Carolina flight tickets

Southwest

Apr 21

MDW6:00 pmChicago Midway

1h 55m

CLT8:55 pmCharlotte Douglas

Apr 28

CLT6:20 pmCharlotte Douglas

2h 05m

MDW7:25 pmChicago Midway

$167

Southwest

Apr 21

MDW3:00 pmChicago Midway

5h 40m

1 stop

CLT9:40 pmCharlotte Douglas

Apr 28

CLT6:20 pmCharlotte Douglas

2h 05m

MDW7:25 pmChicago Midway

$177

Southwest

Apr 21

MDW10:15 amChicago Midway

10h 25m

2 stops

CLT9:40 pmCharlotte Douglas

Apr 28

CLT6:20 pmCharlotte Douglas

2h 05m

MDW7:25 pmChicago Midway

$182

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Mon 4/20

1:12 pm-4:22 pm

Nonstop2h 10m

Charlotte Douglas

Thu 4/23

4:19 pm-5:53 pm

Nonstop2h 34m

$112

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Mon 4/27

12:37 pm-3:45 pm

Nonstop2h 08m

Charlotte Douglas

Thu 4/30

4:19 pm-5:53 pm

Nonstop2h 34m

$113

Quickest round-trip

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 4/21

6:00 pm-8:55 pm

Nonstop1h 55m

Charlotte Douglas

Tue 4/28

6:20 pm-7:25 pm

Nonstop2h 05m

$167

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 4/21

3:00 pm-9:40 pm

1 stop5h 40m

Charlotte Douglas

Tue 4/28

6:20 pm-7:25 pm

Nonstop2h 05m

$177

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Tue 4/14

5:45 pm-8:47 pm

Nonstop2h 02m

Greenville

Tue 4/28

10:36 am-11:53 am

Nonstop2h 17m

$249

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 4/15

8:00 am-11:01 am

Nonstop2h 01m

Greenville

Sat 4/18

7:30 am-8:56 am

Nonstop2h 26m

$252

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 5/16

7:59 pm-11:02 pm

Nonstop2h 03m

Greenville

Tue 5/19

8:14 pm-9:36 pm

Nonstop2h 22m

$255

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Tue 4/14

8:45 am-2:12 pm

1 stop4h 27m

Greenville

Tue 4/28

6:30 am-7:54 am

Nonstop2h 24m

$259

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Wed 5/20

5:05 am-7:33 pm

1 stop13h 28m

Myrtle Beach Intl

Sat 5/23

11:52 am-9:31 am

1 stop22h 39m

$274

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Thu 5/14

11:51 am-8:58 pm

2 stops8h 07m

Myrtle Beach Intl

Mon 5/18

11:52 am-10:46 am

2 stops23h 54m

$275

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Chicago to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Chicago is in August. Flight prices, which tend to average around $330, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Chicago during January instead. Flights to South Carolina in January, while not as cheap as those in August, still average around $350.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $348. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $392.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Chicago to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $365. Try not to purchase tickets in the morning because they tend to be around $378. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to South Carolina flight route?

Fly from Chicago O'Hare Intl to Greenville for the best Chicago - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $375 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Chicago for as low as $306 on momondo.

What cabin class options are available on Chicago to South Carolina flights?

There are 4 cabin classes available to choose from on Chicago to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to South Carolina flights?

You could potentially save up to 27% on your flight if you consider stops on a Chicago to South Carolina flight.

Cheap Chicago to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South Carolina

Best Price Found	$176
Fastest flight time	1h 50m
Direct flights	Every day
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Chicago in the past 72 hours is $176. The best round-trip flight deal from Chicago to South Carolina found on momondo in the last 72 hours is $267.

The fastest flight from Chicago to South Carolina takes 1h 50m

Direct flights go from Chicago to South Carolina every day.

There are 57 airports in South Carolina. From Chicago there are direct flights to Greenville (GSP), Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from Chicago to South Carolina?
Prices for flights from Chicago to South Carolina were last updated today.
How many operators does momondo search for flights from Chicago to South Carolina?
The number of operators available for flights from Chicago to South Carolina is 7 as of March 2026.
How old do you have to be to fly from Chicago to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Chicago to South Carolina?
Based on momondo bookings for flights between Chicago and South Carolina, the leading plane model is Embraer 175 (Enhanced Winglets), making up 20.74% of the total bookings. Other popular models include Embraer 175 with 20.35%, Airbus A319 with 17.42%, and Canadair (Bombardier) Regional Jet CRJ-550 with 7.40%.

Best airlines flying from Chicago to South Carolina

Compare and see reviews for airlines that fly from Chicago to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $51	Free Cancellation	Rating 6.3 8,536 reviews	Search Spirit Airlines flights
Delta	PriceFrom $118	Free Cancellation	Rating 7.9 8,320 reviews	Search Delta flights
Southwest	PriceFrom $153	Free Cancellation	Rating 8.0 4,331 reviews	Search Southwest flights
United Airlines	PriceFrom $186	Free Cancellation	Rating 7.4 9,469 reviews	Search United Airlines flights
American Airlines	PriceFrom $202	Free Cancellation	Rating 7.1 11,491 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to South Carolina for you.

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South Carolina?

Once you have performed a search for Chicago to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Chicago and alert you when they change.

An easier way to manage your South Carolina trip

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Popular cities in South Carolina

Flights to New Yorkfrom $66

Flights to Los Angelesfrom $60

Flights to Orlandofrom $49

Flights to Miamifrom $45

Flights to Chicagofrom $68

Flights to San Franciscofrom $77

Flights to Las Vegasfrom $41

Flights to Washington, D.C.from $59

Flights to Bostonfrom $65

Flights to Atlantafrom $53

Flights to Dallasfrom $62

Flights to Seattlefrom $104

Cheap flights from Chicago to South Carolina from $68

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to South Carolina departing on 4/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from Chicago to South Carolina

Our best Frontier deals on Chicago to South Carolina flight tickets

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See travel insights to South Carolina from

How to get the cheapest flight ticket from Chicago to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Chicago to South Carolina flight route?

How far in advance should I book a flight to South Carolina?

What cabin class options are available on Chicago to South Carolina flights?

Can stopping save me money on Chicago to South Carolina flights?

What is the cheapest airline that flies from Chicago to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Chicago to South Carolina on average per day?

How many flights depart from Chicago to South Carolina on average per week?

Cheap Chicago to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Best airlines flying from Chicago to South Carolina

Compare and see reviews for airlines that fly from Chicago to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

Chicago flight routes

According to popular flight searches on momondo this year

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