What is the cheapest airline that flies from Chicago to South Carolina?

Southwest, Delta, and United Airlines are the most popular carriers operating from Chicago to South Carolina

How many flights depart from Chicago to South Carolina on average per week?

772 flights are operational weekly from Chicago to South Carolina as of June 2026. The most popular departure day for this route is Fri, with 18% of flights per week taking off on this day.

What airlines fly to South Carolina?

United Airlines, American Airlines and Southwest are the top three most popular airlines that fly to South Carolina from Chicago according to our data. United Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Chicago to South Carolina on average per day?

As of June 2026, there are 110 flights per day flying from Chicago to South Carolina. The most common time of day flights depart is 10:00AM, with 40% of flights taking off at noon.

When did momondo last update prices for flights from Chicago to South Carolina?

Prices for flights from Chicago to South Carolina were last updated today.

How many operators does momondo search for flights from Chicago to South Carolina?

The number of operators available for flights from Chicago to South Carolina is 6 as of June 2026.

How old do you have to be to fly from Chicago to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$96 Cheap Flights from Chicago to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Chicago to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:10 am - 11:32 am

ORD

SAV

2h 22mnonstop

12:02 pm - 1:38 pm

SAV

ORD

2h 36mnonstop

$258American Airlines

Thu, Aug 6 - Wed, Aug 12

8:00 am - 11:10 am

MDW

CLT

2h 10mnonstop

7:20 pm - 10:20 pm

CLT

MDW

4h 00m

1 stop

$259Southwest

Thu, Aug 6 - Mon, Aug 10

8:05 am - 9:07 pm

ORD

CLT

12h 02m

1 stop

12:24 pm - 11:10 pm

CLT

ORD

11h 46m

1 stop

$259Frontier

Tue, Jul 21 - Wed, Jul 22

1:50 pm - 6:03 pm

ORD

CLT

27h 13m

2 stops

6:41 pm - 12:15 pm

CLT

ORD

18h 34m

1 stop

$260Frontier

Fri, Jul 17 - Tue, Jul 21

8:45 am - 11:55 am

MDW

CLT

2h 10mnonstop

7:55 am - 8:50 am

CLT

MDW

1h 55mnonstop

$260Southwest

Tue, Aug 4 - Sat, Aug 8

11:00 am - 2:19 pm

ORD

MYR

2h 19mnonstop

6:21 pm - 7:56 pm

MYR

ORD

2h 35mnonstop

$261United Airlines

Wed, Aug 5 - Wed, Aug 12

8:15 am - 11:34 am

ORD

MYR

2h 19mnonstop

5:27 pm - 9:57 pm

MYR

ORD

5h 30m

1 stop

$263American Airlines

Mon, Aug 10 - Sat, Aug 15

2:09 pm - 5:40 pm

ORD

SAV

2h 31mnonstop

3:30 pm - 10:18 pm

SAV

ORD

7h 48m

1 stop

$264United Airlines

Mon, Oct 26 - Wed, Oct 28

9:19 am - 3:55 pm

MDW

CLT

5h 36m

1 stop

5:39 pm - 10:15 pm

CLT

MDW

5h 36m

1 stop

$267Delta

Tue, Jul 21 - Sat, Jul 25

7:00 am - 12:17 pm

ORD

CLT

4h 17m

1 stop

1:17 pm - 4:17 pm

CLT

ORD

4h 00m

1 stop

$267Delta

Sat, Aug 22 - Sat, Aug 29

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Frontier flights from Chicago to South Carolina

Our best Frontier deals on Chicago to South Carolina flight tickets

Frontier

Jul 21

ORD8:05 amChicago O'Hare Intl

12h 02m

1 stop

CLT9:07 pmCharlotte Douglas

Jul 28

CLT5:57 pmCharlotte Douglas

7h 52m

1 stop

ORD12:49 amChicago O'Hare Intl

$259

Frontier

Jul 17

ORD1:50 pmChicago O'Hare Intl

27h 13m

2 stops

CLT6:03 pmCharlotte Douglas

Jul 21

CLT6:41 pmCharlotte Douglas

18h 34m

1 stop

ORD12:15 pmChicago O'Hare Intl

$260

Frontier

Oct 17

ORD6:05 amChicago O'Hare Intl

9h 33m

1 stop

CLT4:38 pmCharlotte Douglas

Oct 19

CLT2:42 pmCharlotte Douglas

10h 42m

1 stop

ORD12:24 amChicago O'Hare Intl

$262

Delta flights from Chicago to South Carolina

Our best Delta deals on Chicago to South Carolina flight tickets

Delta

Aug 22

ORD7:00 amChicago O'Hare Intl

4h 17m

1 stop

CLT12:17 pmCharlotte Douglas

Aug 29

CLT1:17 pmCharlotte Douglas

4h 00m

1 stop

ORD4:17 pmChicago O'Hare Intl

$267

Delta

Aug 20

MDW12:46 pmChicago Midway

4h 21m

1 stop

MYR6:07 pmMyrtle Beach Intl

Aug 24

MYR7:02 pmMyrtle Beach Intl

4h 34m

1 stop

MDW10:36 pmChicago Midway

$273

Delta

Aug 17

ORD7:00 amChicago O'Hare Intl

4h 17m

1 stop

CLT12:17 pmCharlotte Douglas

Aug 22

CLT5:30 pmCharlotte Douglas

4h 25m

1 stop

ORD8:55 pmChicago O'Hare Intl

$278

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Thu 8/6

8:10 am-11:32 am

Nonstop2h 22m

Savannah/Hilton Head

Wed 8/12

12:02 pm-1:38 pm

Nonstop2h 36m

$258

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 8/6

8:00 am-11:10 am

Nonstop2h 10m

Charlotte Douglas

Mon 8/10

7:20 pm-10:20 pm

1 stop4h 00m

$259

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 7/21

8:05 am-9:07 pm

1 stop12h 02m

Charlotte Douglas

Wed 7/22

12:24 pm-11:10 pm

1 stop11h 46m

$259

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 7/17

1:50 pm-6:03 pm

2 stops27h 13m

Charlotte Douglas

Tue 7/21

6:41 pm-12:15 pm

1 stop18h 34m

$260

Quickest round-trip

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 8/4

8:45 am-11:55 am

Nonstop2h 10m

Charlotte Douglas

Sat 8/8

7:55 am-8:50 am

Nonstop1h 55m

$260

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Wed 8/5

11:00 am-2:19 pm

Nonstop2h 19m

Myrtle Beach Intl

Wed 8/12

6:21 pm-7:56 pm

Nonstop2h 35m

$261

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Mon 8/10

8:15 am-11:34 am

Nonstop2h 19m

Myrtle Beach Intl

Sat 8/15

5:27 pm-9:57 pm

1 stop5h 30m

$263

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Mon 10/26

2:09 pm-5:40 pm

Nonstop2h 31m

Savannah/Hilton Head

Wed 10/28

3:30 pm-10:18 pm

1 stop7h 48m

$264

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 7/21

9:19 am-3:55 pm

1 stop5h 36m

Charlotte Douglas

Sat 7/25

5:39 pm-10:15 pm

1 stop5h 36m

$267

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 8/22

7:00 am-12:17 pm

1 stop4h 17m

Charlotte Douglas

Sat 8/29

1:17 pm-4:17 pm

1 stop4h 00m

$267

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Chicago to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Chicago is in September. Flight prices, which tend to average around $50, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Chicago during February instead. Flights to South Carolina in February, while not as cheap as those in September, still average around $101.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $347. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $403.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Chicago to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $368. Try not to purchase tickets in the morning because they tend to be around $383. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to South Carolina flight route?

Fly from Chicago O'Hare Intl to Myrtle Beach Intl for the best Chicago - South Carolina flight prices

How far in advance should I book a flight from Chicago to South Carolina?

You are more likely to see cheaper flights to South Carolina from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $380 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Chicago for as low as $329 on momondo.

What cabin class options are available on Chicago to South Carolina flights?

There are 4 cabin classes available to choose from on Chicago to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Chicago to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South Carolina

Best Price Found	$149
Fastest flight time	1h 50m
Direct flights	Every day
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Chicago in the past 72 hours is $149. The best round-trip flight deal from Chicago to South Carolina found on momondo in the last 72 hours is $274.

The fastest flight from Chicago to South Carolina takes 1h 50m

Direct flights go from Chicago to South Carolina every day.

There are 57 airports in South Carolina. From Chicago there are direct flights to Greenville (GSP), Myrtle Beach Intl (MYR), Charlotte Douglas (CLT), Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Chicago to South Carolina

When did momondo last update prices for flights from Chicago to South Carolina?
Prices for flights from Chicago to South Carolina were last updated today.
How many operators does momondo search for flights from Chicago to South Carolina?
The number of operators available for flights from Chicago to South Carolina is 6 as of June 2026.
How old do you have to be to fly from Chicago to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Chicago to South Carolina?
Based on momondo bookings for flights between Chicago and South Carolina, the leading plane model is Embraer 175, making up 22.24% of the total bookings. Other popular models include Embraer 175 (Enhanced Winglets) with 20.22%, Airbus A319 with 13.64%, and Boeing 737-800 with 12.88%.

Best airlines flying from Chicago to South Carolina

Compare and see reviews for airlines that fly from Chicago to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $146	Free Cancellation	Rating 7.8 8,449 reviews	Search Delta flights
Southwest	PriceFrom $153	Free Cancellation	Rating 7.9 4,246 reviews	Search Southwest flights
American Airlines	PriceFrom $202	Free Cancellation	Rating 7.1 11,770 reviews	Search American Airlines flights
United Airlines	PriceFrom $209	Free Cancellation	Rating 7.4 9,894 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to South Carolina for you.

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South Carolina?

Once you have performed a search for Chicago to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Chicago and alert you when they change.

An easier way to manage your South Carolina trip

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Popular cities in South Carolina

Flights to New Yorkfrom $77

Flights to Los Angelesfrom $60

Flights to Orlandofrom $62

Flights to Miamifrom $78

Flights to Chicagofrom $62

Flights to San Franciscofrom $55

Flights to Las Vegasfrom $56

Flights to Washington, D.C.from $55

Flights to Bostonfrom $61

Flights to Atlantafrom $56

Flights to Fort Lauderdalefrom $58

Flights to Dallasfrom $105

Cheap flights from Chicago to South Carolina from $96

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to South Carolina departing on 8/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from Chicago to South Carolina

Our best Frontier deals on Chicago to South Carolina flight tickets

Delta flights from Chicago to South Carolina

Our best Delta deals on Chicago to South Carolina flight tickets

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How to get the cheapest flight ticket from Chicago to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Chicago to South Carolina flight route?

How far in advance should I book a flight from Chicago to South Carolina?

What cabin class options are available on Chicago to South Carolina flights?

What is the cheapest airline that flies from Chicago to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Chicago to South Carolina on average per day?

How many flights depart from Chicago to South Carolina on average per week?

Cheap Chicago to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Frequently asked questions about flying from Chicago to South Carolina

Best airlines flying from Chicago to South Carolina

Compare and see reviews for airlines that fly from Chicago to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

Chicago flight routes

According to popular flight searches on momondo this year

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