What is the cheapest airline that flies from Chicago to South Carolina?

Southwest, Delta, and United Airlines are the most popular carriers operating from Chicago to South Carolina

How many flights depart from Chicago to South Carolina on average per day?

As of May 2026, there are 110 flights per day flying from Chicago to South Carolina. The most common time of day flights depart is 7:00PM, with 46% of flights taking off at noon.

What airlines fly to South Carolina?

United Airlines, American Airlines and Spirit Airlines are the top three most popular airlines that fly to South Carolina from Chicago according to our data. United Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Chicago to South Carolina on average per week?

772 flights are operational weekly from Chicago to South Carolina as of May 2026. The most popular departure day for this route is Mon, with 17% of flights per week taking off on this day.

When did momondo last update prices for flights from Chicago to South Carolina?

Prices for flights from Chicago to South Carolina were last updated today.

How many operators does momondo search for flights from Chicago to South Carolina?

The number of operators available for flights from Chicago to South Carolina is 7 as of May 2026.

How old do you have to be to fly from Chicago to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$77 Cheap Flights from Chicago to South Carolina in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Chicago to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:59 pm - 4:53 pm

ORD

CLT

22h 54m

1 stop

10:01 am - 12:48 am

CLT

ORD

15h 47m

1 stop

$190Frontier

Tue, Jun 16 - Tue, Jun 23

5:29 pm - 12:37 pm

ORD

CLT

18h 08m

1 stop

5:57 pm - 12:49 am

CLT

ORD

7h 52m

1 stop

$196Frontier

Wed, Jun 24 - Tue, Jul 21

12:45 pm - 3:40 pm

MDW

CLT

1h 55mnonstop

6:00 pm - 7:00 pm

CLT

MDW

2h 00mnonstop

$259Southwest

Tue, Jun 16 - Sat, Jun 20

8:00 am - 11:01 am

ORD

GSP

2h 01mnonstop

7:20 pm - 8:51 pm

GSP

ORD

2h 31mnonstop

$262American Airlines

Fri, Jul 3 - Thu, Jul 9

7:15 pm - 10:18 pm

ORD

GSP

2h 03mnonstop

6:41 pm - 8:15 pm

GSP

ORD

2h 34mnonstop

$263American Airlines

Thu, May 28 - Mon, Jun 1

5:30 am - 1:04 pm

ORD

MYR

6h 34m

1 stop

11:32 am - 4:26 pm

MYR

ORD

5h 54m

1 stop

$264Delta

Tue, Jun 9 - Thu, Jun 11

10:43 am - 2:02 pm

ORD

MYR

2h 19mnonstop

11:24 am - 1:09 pm

MYR

ORD

2h 45mnonstop

$265United Airlines

Tue, Jun 2 - Tue, Jun 9

11:00 am - 2:19 pm

ORD

MYR

2h 19mnonstop

3:15 pm - 4:49 pm

MYR

ORD

2h 34mnonstop

$266United Airlines

Tue, Jun 30 - Tue, Jul 7

6:45 pm - 9:45 pm

MDW

MYR

2h 00mnonstop

7:55 am - 9:00 am

MYR

MDW

2h 05mnonstop

$266Southwest

Wed, Jul 1 - Wed, Jul 8

6:40 am - 1:33 pm

ORD

MYR

5h 53m

1 stop

2:18 pm - 6:46 pm

MYR

ORD

5h 28m

1 stop

$269Delta

Tue, Aug 11 - Mon, Aug 17

Frontier flights from Chicago to South Carolina

Our best Frontier deals on Chicago to South Carolina flight tickets

Frontier

Jun 16

ORD4:59 pmChicago O'Hare Intl

22h 54m

1 stop

CLT4:53 pmCharlotte Douglas

Jun 23

CLT10:01 amCharlotte Douglas

15h 47m

1 stop

ORD12:48 amChicago O'Hare Intl

$190

Frontier

Jun 24

ORD5:29 pmChicago O'Hare Intl

18h 08m

1 stop

CLT12:37 pmCharlotte Douglas

Jul 21

CLT5:57 pmCharlotte Douglas

7h 52m

1 stop

ORD12:49 amChicago O'Hare Intl

$196

Frontier

Aug 12

ORD5:46 pmChicago O'Hare Intl

17h 43m

1 stop

CLT12:29 pmCharlotte Douglas

Aug 18

CLT5:59 pmCharlotte Douglas

7h 43m

1 stop

ORD12:42 amChicago O'Hare Intl

$197

Contour flights from Chicago to South Carolina

Our best Contour deals on Chicago to South Carolina flight tickets

Contour

Jun 18

ORD11:20 amChicago O'Hare Intl

4h 40m

1 stop

CLT5:00 pmCharlotte Douglas

Jun 21

CLT6:05 pmCharlotte Douglas

17h 35m

1 stop

ORD10:40 amChicago O'Hare Intl

$209

Contour

May 20

ORD11:20 amChicago O'Hare Intl

4h 40m

1 stop

CLT5:00 pmCharlotte Douglas

May 22

CLT6:05 pmCharlotte Douglas

17h 35m

1 stop

ORD10:40 amChicago O'Hare Intl

$236

Contour

Jul 10

ORD11:20 amChicago O'Hare Intl

4h 40m

1 stop

CLT5:00 pmCharlotte Douglas

Jul 13

CLT6:05 pmCharlotte Douglas

25h 00m

1 stop

ORD6:05 pmChicago O'Hare Intl

$237

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 6/16

4:59 pm-4:53 pm

1 stop22h 54m

Charlotte Douglas

Tue 6/23

10:01 am-12:48 am

1 stop15h 47m

$190

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Wed 6/24

5:29 pm-12:37 pm

1 stop18h 08m

Charlotte Douglas

Tue 7/21

5:57 pm-12:49 am

1 stop7h 52m

$196

Quickest round-trip

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 6/16

12:45 pm-3:40 pm

Nonstop1h 55m

Charlotte Douglas

Sat 6/20

6:00 pm-7:00 pm

Nonstop2h 00m

$259

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 7/3

8:00 am-11:01 am

Nonstop2h 01m

Greenville

Thu 7/9

7:20 pm-8:51 pm

Nonstop2h 31m

$262

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 5/28

7:15 pm-10:18 pm

Nonstop2h 03m

Greenville

Mon 6/1

6:41 pm-8:15 pm

Nonstop2h 34m

$263

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Tue 6/9

5:30 am-1:04 pm

1 stop6h 34m

Myrtle Beach Intl

Thu 6/11

11:32 am-4:26 pm

1 stop5h 54m

$264

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Tue 6/2

10:43 am-2:02 pm

Nonstop2h 19m

Myrtle Beach Intl

Tue 6/9

11:24 am-1:09 pm

Nonstop2h 45m

$265

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Tue 6/30

11:00 am-2:19 pm

Nonstop2h 19m

Myrtle Beach Intl

Tue 7/7

3:15 pm-4:49 pm

Nonstop2h 34m

$266

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

Wed 7/1

6:45 pm-9:45 pm

Nonstop2h 00m

Myrtle Beach Intl

Wed 7/8

7:55 am-9:00 am

Nonstop2h 05m

$266

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Tue 8/11

6:40 am-1:33 pm

1 stop5h 53m

Myrtle Beach Intl

Mon 8/17

2:18 pm-6:46 pm

1 stop5h 28m

$269

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Chicago to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Chicago is in September. Flight prices, which tend to average around $50, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Chicago during February instead. Flights to South Carolina in February, while not as cheap as those in September, still average around $101.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $348. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $405.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Chicago to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $366. Try not to purchase tickets in the morning because they tend to be around $379. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to South Carolina flight route?

Fly from Chicago Midway to Charleston for the best Chicago - South Carolina flight prices

How far in advance should I book a flight from Chicago to South Carolina?

You are more likely to see cheaper flights to South Carolina from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $377 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Chicago for as low as $293 on momondo.

Can stopping save me money on Chicago to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Chicago to South Carolina.

Cheap Chicago to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South Carolina

Best Price Found	$132
Fastest flight time	1h 50m
Direct flights	Every day
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Chicago in the past 72 hours is $132. The best round-trip flight deal from Chicago to South Carolina found on momondo in the last 72 hours is $279.

The fastest flight from Chicago to South Carolina takes 1h 50m

Direct flights go from Chicago to South Carolina every day.

There are 57 airports in South Carolina. From Chicago there are direct flights to Greenville (GSP), Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Chicago to South Carolina

When did momondo last update prices for flights from Chicago to South Carolina?
Prices for flights from Chicago to South Carolina were last updated today.
How many operators does momondo search for flights from Chicago to South Carolina?
The number of operators available for flights from Chicago to South Carolina is 7 as of May 2026.
How old do you have to be to fly from Chicago to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Chicago to South Carolina?
Based on momondo bookings for flights between Chicago and South Carolina, the leading plane model is Embraer 175, making up 20.25% of the total bookings. Other popular models include Embraer 175 (Enhanced Winglets) with 20.18%, Airbus A319 with 15.42%, and Boeing 737-800 with 10.75%.

Best airlines flying from Chicago to South Carolina

Compare and see reviews for airlines that fly from Chicago to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $51	Free Cancellation	Rating 6.3 8,632 reviews	Search Spirit Airlines flights
Delta	PriceFrom $146	Free Cancellation	Rating 7.9 8,446 reviews	Search Delta flights
Southwest	PriceFrom $153	Free Cancellation	Rating 8.0 4,295 reviews	Search Southwest flights
United Airlines	PriceFrom $197	Free Cancellation	Rating 7.4 9,701 reviews	Search United Airlines flights
American Airlines	PriceFrom $202	Free Cancellation	Rating 7.1 11,661 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to South Carolina for you.

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to South Carolina?

Once you have performed a search for Chicago to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Chicago and alert you when they change.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Thu 6/11

Thu 6/18

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South Carolina

Popular cities

Other flights from Chicago

Other flights to South Carolina

Airlines

Complete your trip

Feeling lucky

Popular cities in South Carolina

Flights to New Yorkfrom $77

Flights to Los Angelesfrom $46

Flights to Orlandofrom $63

Flights to Miamifrom $56

Flights to Chicagofrom $59

Flights to San Franciscofrom $58

Flights to Las Vegasfrom $48

Flights to Washington, D.C.from $57

Flights to Bostonfrom $83

Flights to Atlantafrom $50

Flights to Fort Lauderdalefrom $56

Flights to Dallasfrom $50

Cheap flights from Chicago to South Carolina from $77

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to South Carolina departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Chicago to South Carolina

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Frontier flights from Chicago to South Carolina

Our best Frontier deals on Chicago to South Carolina flight tickets

Contour flights from Chicago to South Carolina

Our best Contour deals on Chicago to South Carolina flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Chicago to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Chicago to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Chicago to South Carolina flight route?

How far in advance should I book a flight from Chicago to South Carolina?

Can stopping save me money on Chicago to South Carolina flights?

What is the cheapest airline that flies from Chicago to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Chicago to South Carolina on average per day?

How many flights depart from Chicago to South Carolina on average per week?

Cheap Chicago to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Frequently asked questions about flying from Chicago to South Carolina

Best airlines flying from Chicago to South Carolina

Compare and see reviews for airlines that fly from Chicago to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

Chicago flight routes

According to popular flight searches on momondo this year

South Carolina flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to South Carolina

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Complete your trip to South Carolina

Explore popular destinations other users love

According to popular flight searches on momondo this year