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Cheap flights from Chicago to Des Moines from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Des Moines departing on 7/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Chicago to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:00 pm - 10:52 pm
ORD
-
DSM
26h 52m
1 stop
Multiple Airlines Logo
4:01 pm - 8:03 am
DSM
-
ORD
40h 02m
2 stops
$242Multiple Airlines
Sat, Jun 6 - Sun, Jun 14
American Airlines Logo
6:00 pm - 7:35 pm
ORD
-
DSM
1h 35mnonstop
American Airlines Logo
8:05 pm - 9:46 pm
DSM
-
ORD
1h 41mnonstop
$257American Airlines
Tue, Jun 16 - Wed, Jun 17
Southwest Logo
10:10 am - 11:30 am
MDW
-
DSM
1h 20mnonstop
Southwest Logo
5:20 am - 6:40 am
DSM
-
MDW
1h 20mnonstop
$257Southwest
Tue, Jun 16 - Wed, Jun 17
Multiple Airlines Logo
1:29 pm - 10:58 pm
ORD
-
DSM
33h 29m
2 stops
Multiple Airlines Logo
10:01 pm - 5:07 am
DSM
-
ORD
31h 06m
1 stop
$261Multiple Airlines
Wed, Jun 3 - Fri, Jul 3
Southwest Logo
10:05 pm - 11:30 pm
MDW
-
DSM
1h 25mnonstop
Southwest Logo
4:40 pm - 6:00 pm
DSM
-
MDW
1h 20mnonstop
$269Southwest
Thu, Jun 4 - Mon, Jun 8
American Airlines Logo
11:50 am - 1:21 pm
ORD
-
DSM
1h 31mnonstop
American Airlines Logo
10:29 am - 12:07 pm
DSM
-
ORD
1h 38mnonstop
$269American Airlines
Thu, Aug 27 - Sat, Aug 29
Frontier Logo
9:48 pm - 1:31 pm
ORD
-
DSM
15h 43m
1 stop
Frontier Logo
2:19 pm - 8:52 pm
DSM
-
ORD
6h 33m
1 stop
$271Frontier
Tue, Jun 30 - Mon, Jul 6
Delta Logo
6:30 am - 10:14 am
ORD
-
DSM
3h 44m
1 stop
Delta Logo
6:08 am - 10:50 am
DSM
-
ORD
4h 42m
1 stop
$277Delta
Tue, Jun 16 - Wed, Jun 17
Delta Logo
9:54 am - 2:05 pm
MDW
-
DSM
4h 11m
1 stop
Delta Logo
6:08 am - 12:46 pm
DSM
-
MDW
6h 38m
1 stop
$277Delta
Wed, Jun 17 - Wed, Jun 24
Frontier Logo
9:37 pm - 1:31 pm
ORD
-
DSM
15h 54m
1 stop
Frontier Logo
2:16 pm - 8:32 pm
DSM
-
ORD
6h 16m
1 stop
$282Frontier
Thu, Jun 4 - Mon, Jun 8

American Airlines flights from Chicago to Des Moines

Our best American Airlines deals on Chicago to Des Moines flight tickets
American Airlines
Jun 16
ORD6:00 pmChicago O'Hare Intl
1h 35m
DSM7:35 pmDes Moines
Jun 17
DSM8:05 pmDes Moines
1h 41m
ORD9:46 pmChicago O'Hare Intl
$257
American Airlines
Aug 27
ORD11:50 amChicago O'Hare Intl
1h 31m
DSM1:21 pmDes Moines
Aug 29
DSM10:29 amDes Moines
1h 38m
ORD12:07 pmChicago O'Hare Intl
$269
American Airlines
Jun 25
ORD5:00 pmChicago O'Hare Intl
1h 39m
DSM6:39 pmDes Moines
Jun 30
DSM1:51 pmDes Moines
1h 42m
ORD3:33 pmChicago O'Hare Intl
$293

Southwest flights from Chicago to Des Moines

Our best Southwest deals on Chicago to Des Moines flight tickets
Southwest
Jun 16
MDW10:10 amChicago Midway
1h 20m
DSM11:30 amDes Moines
Jun 17
DSM5:20 amDes Moines
1h 20m
MDW6:40 amChicago Midway
$257
Southwest
Aug 27
MDW8:50 pmChicago Midway
1h 20m
DSM10:10 pmDes Moines
Aug 29
DSM12:10 pmDes Moines
1h 20m
MDW1:30 pmChicago Midway
$269
Southwest
Jun 16
MDW10:10 amChicago Midway
1h 20m
DSM11:30 amDes Moines
Jun 18
DSM4:40 pmDes Moines
1h 20m
MDW6:00 pmChicago Midway
$293

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Chicago to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sat 6/6

8:00 pm-10:52 pm

1 stop26h 52m

Des Moines

Sun 6/14

4:01 pm-8:03 am

2 stops40h 02m

$242

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Tue 6/16

6:00 pm-7:35 pm

Nonstop1h 35m

Des Moines

Wed 6/17

8:05 pm-9:46 pm

Nonstop1h 41m

$257
Quickest round-trip

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Tue 6/16

10:10 am-11:30 am

Nonstop1h 20m

Des Moines

Wed 6/17

5:20 am-6:40 am

Nonstop1h 20m

$257

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Wed 6/3

1:29 pm-10:58 pm

2 stops33h 29m

Des Moines

Fri 7/3

10:01 pm-5:07 am

1 stop31h 06m

$261

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Thu 6/4

10:05 pm-11:30 pm

Nonstop1h 25m

Des Moines

Mon 6/8

4:40 pm-6:00 pm

Nonstop1h 20m

$269

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 8/27

11:50 am-1:21 pm

Nonstop1h 31m

Des Moines

Sat 8/29

10:29 am-12:07 pm

Nonstop1h 38m

$269

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Tue 6/30

9:48 pm-1:31 pm

1 stop15h 43m

Des Moines

Mon 7/6

2:19 pm-8:52 pm

1 stop6h 33m

$271

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Tue 6/16

6:30 am-10:14 am

1 stop3h 44m

Des Moines

Wed 6/17

6:08 am-10:50 am

1 stop4h 42m

$277

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 6/17

9:54 am-2:05 pm

1 stop4h 11m

Des Moines

Wed 6/24

6:08 am-12:46 pm

1 stop6h 38m

$277

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 6/4

9:37 pm-1:31 pm

1 stop15h 54m

Des Moines

Mon 6/8

2:16 pm-8:32 pm

1 stop6h 16m

$282

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Chicago to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in April, then February is your next best option. Flight prices from Chicago to Des Moines during February average around $126.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Chicago to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $240. Flights from Chicago to Des Moines on a Tuesday will generally be more expensive and average around $473. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Chicago to Des Moines at noon for as low as $224. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $414. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to Des Moines flight route?

Fly from Chicago O'Hare Intl to Des Moines for the best Chicago - Des Moines flight prices

What cabin class options are available on Chicago to Des Moines flights?

There are 4 cabin classes available to choose from on Chicago to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Des Moines flights?

You could potentially save up to 43% on your flight if you consider stops on a Chicago to Des Moines flight.

How have Chicago to Des Moines flight prices changed over time?

As of May 2026, prices for Chicago to Des Moines flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Des Moines (CHI to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Des Moines

Best Price Found

$164

Fastest flight time

1h 20m

Direct flights

Every day

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Chicago in the past 72 hours is $164. The best round-trip flight deal from Chicago to Des Moines found on momondo in the last 72 hours is $461.
The fastest flight from Chicago to Des Moines takes 1h 20m
Direct flights go from Chicago to Des Moines every day.
There is 1 airport in Des Moines. From Chicago there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from Chicago to Des Moines

  • How far is Chicago to Des Moines by plane?

    Chicago and Des Moines are 309.8 mi apart from one another. A reasonable flight in good conditions will take 1h 20m.

  • When did momondo last update prices for flights from Chicago to Des Moines Airport?

    Prices for flights from Chicago to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Des Moines Airport?

  • How old do you have to be to fly from Chicago to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago to Des Moines?

  • What is the most popular airline from Chicago to Des Moines?

Best airlines flying from Chicago to Des Moines

Compare and see reviews for airlines that fly from Chicago to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $189Free CancellationRating
7.1
11,642 reviews
Search American Airlines flights
United AirlinesPriceFrom $189Free CancellationRating
7.4
9,737 reviews
Search United Airlines flights

  • United Airlines Flights From Chicago to Des Moines

    United Airlines flies from Chicago to Des Moines around 8 times per week, with 9,737 momondo users rating the airline 7.4/10. The cheapest United Airlines deal from Chicago to Des Moines in the last 72 hours was $189 (round-trip), much lower than the average airfare cost of $384 for United Airlines flights on this route.

  • American Airlines Flights From Chicago to Des Moines

    Across 11,642 American Airlines reviews on momondo, the average score is 7.1/10. American Airlines flies from Chicago to Des Moines about 14 times each week, with ticket deals ranging from $189 to $268. Price data is based on momondo searches in the last 72 hours.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Des Moines?

It is quick and easy to find Chicago to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Chicago to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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