Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Charlotte to Des Moines from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Des Moines departing on 5/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Charlotte to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:41 pm - 3:15 pm
CLT
-
DSM
21h 34m
1 stop
Multiple Airlines Logo
2:16 pm - 4:00 pm
DSM
-
CLT
24h 44m
2 stops
$263Multiple Airlines
Wed, May 13 - Wed, May 27
Southwest Logo
7:35 am - 11:25 am
CLT
-
DSM
4h 50m
1 stop
Southwest Logo
3:15 pm - 8:55 pm
DSM
-
CLT
4h 40m
1 stop
$267Southwest
Wed, May 20 - Wed, May 27
Multiple Airlines Logo
6:00 am - 5:54 pm
CLT
-
DSM
12h 54m
1 stop
Multiple Airlines Logo
5:02 pm - 9:57 am
DSM
-
CLT
15h 55m
1 stop
$280Multiple Airlines
Fri, Jun 12 - Sun, Jun 14
Southwest Logo
7:35 am - 11:25 am
CLT
-
DSM
4h 50m
1 stop
Southwest Logo
3:15 pm - 8:55 pm
DSM
-
CLT
4h 40m
1 stop
$283Southwest
Tue, Apr 14 - Tue, Apr 21
Multiple Airlines Logo
8:56 am - 4:00 pm
CLT
-
DSM
8h 04m
1 stop
Multiple Airlines Logo
7:00 am - 8:37 pm
DSM
-
CLT
12h 37m
2 stops
$284Multiple Airlines
Thu, Apr 23 - Thu, Apr 30
Multiple Airlines Logo
6:00 am - 5:54 pm
CLT
-
DSM
12h 54m
1 stop
Multiple Airlines Logo
5:02 pm - 9:57 am
DSM
-
CLT
15h 55m
1 stop
$286Multiple Airlines
Fri, Jun 12 - Sun, Jun 14
Southwest Logo
1:45 pm - 10:10 pm
CLT
-
DSM
9h 25m
2 stops
Southwest Logo
3:15 pm - 8:55 pm
DSM
-
CLT
4h 40m
1 stop
$288Southwest
Tue, Apr 14 - Tue, Apr 21
Multiple Airlines Logo
8:56 am - 4:00 pm
CLT
-
DSM
8h 04m
1 stop
Multiple Airlines Logo
2:36 pm - 9:10 am
DSM
-
CLT
17h 34m
1 stop
$290Multiple Airlines
Thu, Apr 23 - Thu, Apr 30
Multiple Airlines Logo
1:00 pm - 10:31 pm
CLT
-
DSM
10h 31m
1 stop
Multiple Airlines Logo
9:00 am - 8:19 pm
DSM
-
CLT
34h 19m
2 stops
$291Multiple Airlines
Thu, May 28 - Sun, May 31
Multiple Airlines Logo
1:00 pm - 9:47 pm
CLT
-
DSM
9h 47m
1 stop
Multiple Airlines Logo
5:45 pm - 9:11 am
DSM
-
CLT
14h 26m
1 stop
$298Multiple Airlines
Thu, Jun 18 - Mon, Jun 29

Southwest flights from Charlotte to Des Moines

Our best Southwest deals on Charlotte to Des Moines flight tickets
Southwest
May 20
CLT7:35 amCharlotte Douglas
4h 50m
1 stop
DSM11:25 amDes Moines
May 27
DSM3:15 pmDes Moines
4h 40m
1 stop
CLT8:55 pmCharlotte Douglas
$267
Southwest
Apr 14
CLT7:35 amCharlotte Douglas
4h 50m
1 stop
DSM11:25 amDes Moines
Apr 21
DSM3:15 pmDes Moines
4h 40m
1 stop
CLT8:55 pmCharlotte Douglas
$283
Southwest
Apr 14
CLT1:45 pmCharlotte Douglas
9h 25m
2 stops
DSM10:10 pmDes Moines
Apr 21
DSM3:15 pmDes Moines
4h 40m
1 stop
CLT8:55 pmCharlotte Douglas
$288

American Airlines flights from Charlotte to Des Moines

Our best American Airlines deals on Charlotte to Des Moines flight tickets
American Airlines
May 13
CLT4:39 pmCharlotte Douglas
8h 10m
1 stop
DSM11:49 pmDes Moines
May 19
DSM8:03 pmDes Moines
11h 03m
1 stop
CLT8:06 amCharlotte Douglas
$365
American Airlines
May 13
CLT8:46 pmCharlotte Douglas
2h 32m
DSM10:18 pmDes Moines
May 19
DSM8:56 amDes Moines
8h 45m
1 stop
CLT6:41 pmCharlotte Douglas
$378
American Airlines
May 13
CLT11:41 amCharlotte Douglas
2h 30m
DSM1:11 pmDes Moines
May 19
DSM1:38 pmDes Moines
2h 24m
CLT5:02 pmCharlotte Douglas
$391

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Charlotte to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 5/13

6:41 pm-3:15 pm

1 stop21h 34m

Des Moines

Wed 5/27

2:16 pm-4:00 pm

2 stops24h 44m

$263
Quickest round-trip

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 5/20

7:35 am-11:25 am

1 stop4h 50m

Des Moines

Wed 5/27

3:15 pm-8:55 pm

1 stop4h 40m

$267

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 6/12

6:00 am-5:54 pm

1 stop12h 54m

Des Moines

Sun 6/14

5:02 pm-9:57 am

1 stop15h 55m

$280

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 4/14

7:35 am-11:25 am

1 stop4h 50m

Des Moines

Tue 4/21

3:15 pm-8:55 pm

1 stop4h 40m

$283

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 4/23

8:56 am-4:00 pm

1 stop8h 04m

Des Moines

Thu 4/30

7:00 am-8:37 pm

2 stops12h 37m

$284

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 6/12

6:00 am-5:54 pm

1 stop12h 54m

Des Moines

Sun 6/14

5:02 pm-9:57 am

1 stop15h 55m

$286

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 4/14

1:45 pm-10:10 pm

2 stops9h 25m

Des Moines

Tue 4/21

3:15 pm-8:55 pm

1 stop4h 40m

$288

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 4/23

8:56 am-4:00 pm

1 stop8h 04m

Des Moines

Thu 4/30

2:36 pm-9:10 am

1 stop17h 34m

$290

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 5/28

1:00 pm-10:31 pm

1 stop10h 31m

Des Moines

Sun 5/31

9:00 am-8:19 pm

2 stops34h 19m

$291

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 6/18

1:00 pm-9:47 pm

1 stop9h 47m

Des Moines

Mon 6/29

5:45 pm-9:11 am

1 stop14h 26m

$298

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Charlotte to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charlotte and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then August is your next best option. Flight prices from Charlotte to Des Moines during August average around $406.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Charlotte to Des Moines is on a Sunday. Travelers who choose to depart for Des Moines on a Sunday will often find tickets for as low as $411. Flights from Charlotte to Des Moines on a Monday will generally be more expensive and average around $528. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Charlotte to Des Moines at noon for as low as $421. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $472. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Charlotte Douglas to Des Moines flight route?

Fly from Charlotte Douglas to Des Moines for the best Charlotte Douglas - Des Moines flight prices

What cabin class options are available on Charlotte Douglas to Des Moines flights?

There are 2 cabin classes available to choose from on Charlotte Douglas to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Charlotte to Des Moines flights?

You could potentially save up to 17% on your flight if you consider stops on a Charlotte to Des Moines flight.

How have Charlotte to Des Moines flight prices changed over time?

When to book flights from Charlotte to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Des Moines (CLT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Des Moines

Best Price Found

$431

Fastest flight time

2h 30m

Direct flights

Every day

Airports in Des Moines

1 airport
The best flight deal from Charlotte to Des Moines found on momondo in the last 72 hours is $431
The fastest flight from Charlotte to Des Moines takes 2h 30m
Direct flights go from Charlotte to Des Moines every day.
There is 1 airport in Des Moines. From Charlotte there are direct flights to Des Moines (DSM).
Search flight deals

  • How far is Charlotte Douglas to Des Moines by plane?

    Charlotte Douglas and Des Moines are 818.0 mi apart from one another. Flights usually cover this in 2h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Des Moines Airport?

    Prices for flights from Charlotte Douglas Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Des Moines Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charlotte Douglas Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Charlotte to Des Moines?

  • What is the most popular airline from Charlotte to Des Moines?

Best airlines flying from Charlotte to Des Moines

Compare and see reviews for airlines that fly from Charlotte to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $335Free CancellationRating
7.1
11,507 reviews
Search American Airlines flights

  • American Airlines Flights From Charlotte to Des Moines

    American Airlines flight deals from Charlotte to Des Moines start from $335 round-trip. Over the 11 American Airlines flights for this route in a normal week, average airfare is usually $442 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Charlotte.

Can I find flights from Charlotte to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Charlotte which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charlotte to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Charlotte.

I’m not ready to book a flight from Charlotte to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charlotte to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 4/26
Sun 5/3
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States