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Cheap flights from Charlotte to Des Moines from $98

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Des Moines departing on 5/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charlotte to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:16 pm - 3:15 pm
CLT
-
DSM
24h 59m
1 stop
Multiple Airlines Logo
7:45 am - 12:05 pm
DSM
-
CLT
27h 20m
1 stop
$214Multiple Airlines
Wed, May 13 - Sun, May 17
Frontier Logo
7:14 pm - 1:31 pm
CLT
-
DSM
19h 17m
1 stop
Frontier Logo
2:16 pm - 6:18 pm
DSM
-
CLT
27h 02m
1 stop
$225Frontier
Thu, May 28 - Mon, Jun 1
Multiple Airlines Logo
6:00 am - 11:27 pm
CLT
-
DSM
18h 27m
1 stop
Multiple Airlines Logo
6:44 pm - 12:14 pm
DSM
-
CLT
16h 30m
1 stop
$240Multiple Airlines
Mon, Jun 8 - Mon, Jun 15
Multiple Airlines Logo
3:16 pm - 3:15 pm
CLT
-
DSM
24h 59m
1 stop
Multiple Airlines Logo
7:45 am - 11:34 am
DSM
-
CLT
26h 49m
1 stop
$243Multiple Airlines
Wed, May 13 - Sun, May 17
Multiple Airlines Logo
7:58 pm - 8:53 am
CLT
-
DSM
13h 55m
1 stop
Multiple Airlines Logo
3:57 pm - 12:05 pm
DSM
-
CLT
19h 08m
1 stop
$247Multiple Airlines
Sat, May 23 - Mon, May 25
Multiple Airlines Logo
3:16 pm - 9:27 pm
CLT
-
DSM
31h 11m
2 stops
Multiple Airlines Logo
4:07 pm - 12:05 pm
DSM
-
CLT
18h 58m
1 stop
$260Multiple Airlines
Wed, Jun 3 - Mon, Jun 8
Multiple Airlines Logo
6:41 pm - 11:24 pm
CLT
-
DSM
29h 43m
1 stop
Multiple Airlines Logo
9:51 pm - 2:11 pm
DSM
-
CLT
15h 20m
2 stops
$261Multiple Airlines
Thu, May 28 - Mon, Jun 1
Multiple Airlines Logo
6:41 pm - 11:24 pm
CLT
-
DSM
29h 43m
1 stop
Multiple Airlines Logo
9:51 pm - 2:11 pm
DSM
-
CLT
15h 20m
2 stops
$264Multiple Airlines
Thu, May 28 - Mon, Jun 1
Multiple Airlines Logo
12:58 pm - 9:27 pm
CLT
-
DSM
9h 29m
1 stop
Multiple Airlines Logo
5:02 pm - 12:03 pm
DSM
-
CLT
18h 01m
1 stop
$268Multiple Airlines
Thu, Jun 4 - Sun, Jun 7
Multiple Airlines Logo
6:00 am - 10:31 pm
CLT
-
DSM
17h 31m
2 stops
Multiple Airlines Logo
3:57 pm - 2:11 pm
DSM
-
CLT
21h 14m
1 stop
$271Multiple Airlines
Thu, May 21 - Mon, May 25

Southwest flights from Charlotte to Des Moines

Our best Southwest deals on Charlotte to Des Moines flight tickets
Southwest
May 9
CLT8:10 amCharlotte Douglas
4h 20m
1 stop
DSM11:30 amDes Moines
May 16
DSM5:35 amDes Moines
5h 00m
1 stop
CLT11:35 amCharlotte Douglas
$379
Southwest
May 9
CLT6:10 amCharlotte Douglas
8h 10m
2 stops
DSM1:20 pmDes Moines
May 16
DSM5:35 amDes Moines
5h 00m
1 stop
CLT11:35 amCharlotte Douglas
$384
Southwest
Jun 3
CLT7:35 amCharlotte Douglas
4h 50m
1 stop
DSM11:25 amDes Moines
Jun 8
DSM4:40 pmDes Moines
4h 10m
1 stop
CLT9:50 pmCharlotte Douglas
$387

United Airlines flights from Charlotte to Des Moines

Our best United Airlines deals on Charlotte to Des Moines flight tickets
United Airlines
May 9
CLT4:18 pmCharlotte Douglas
8h 26m
1 stop
DSM11:44 pmDes Moines
May 10
DSM11:40 amDes Moines
4h 31m
1 stop
CLT5:11 pmCharlotte Douglas
$485
United Airlines
May 9
CLT4:18 pmCharlotte Douglas
8h 26m
1 stop
DSM11:44 pmDes Moines
May 10
DSM6:15 amDes Moines
6h 53m
2 stops
CLT2:08 pmCharlotte Douglas
$491
United Airlines
May 1
CLT8:05 amCharlotte Douglas
7h 19m
1 stop
DSM2:24 pmDes Moines
May 3
DSM1:35 pmDes Moines
8h 15m
1 stop
CLT10:50 pmCharlotte Douglas
$510

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Charlotte to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 5/13

3:16 pm-3:15 pm

1 stop24h 59m

Des Moines

Sun 5/17

7:45 am-12:05 pm

1 stop27h 20m

$214

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 5/28

7:14 pm-1:31 pm

1 stop19h 17m

Des Moines

Mon 6/1

2:16 pm-6:18 pm

1 stop27h 02m

$225

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 6/8

6:00 am-11:27 pm

1 stop18h 27m

Des Moines

Mon 6/15

6:44 pm-12:14 pm

1 stop16h 30m

$240

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 5/13

3:16 pm-3:15 pm

1 stop24h 59m

Des Moines

Sun 5/17

7:45 am-11:34 am

1 stop26h 49m

$243

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sat 5/23

7:58 pm-8:53 am

1 stop13h 55m

Des Moines

Mon 5/25

3:57 pm-12:05 pm

1 stop19h 08m

$247

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 6/3

3:16 pm-9:27 pm

2 stops31h 11m

Des Moines

Mon 6/8

4:07 pm-12:05 pm

1 stop18h 58m

$260

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 5/28

6:41 pm-11:24 pm

1 stop29h 43m

Des Moines

Mon 6/1

9:51 pm-2:11 pm

2 stops15h 20m

$261

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 5/28

6:41 pm-11:24 pm

1 stop29h 43m

Des Moines

Mon 6/1

9:51 pm-2:11 pm

2 stops15h 20m

$264
Quickest round-trip

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 6/4

12:58 pm-9:27 pm

1 stop9h 29m

Des Moines

Sun 6/7

5:02 pm-12:03 pm

1 stop18h 01m

$268

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 5/21

6:00 am-10:31 pm

2 stops17h 31m

Des Moines

Mon 5/25

3:57 pm-2:11 pm

1 stop21h 14m

$271

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Charlotte to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charlotte and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then August is your next best option. Flight prices from Charlotte to Des Moines during August average around $406.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Charlotte to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $406. Flights from Charlotte to Des Moines on a Monday will generally be more expensive and average around $528. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Charlotte to Des Moines in the afternoon for as low as $421. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $463. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Charlotte Douglas to Des Moines flight route?

Fly from Charlotte Douglas to Des Moines for the best Charlotte Douglas - Des Moines flight prices

How far in advance should I book a flight from Charlotte to Des Moines?

You are more likely to see cheaper flights to Des Moines from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $435 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from Charlotte for as low as $395 on momondo.

Can stopping save me money on Charlotte to Des Moines flights?

You could potentially save up to 37% on your flight if you consider stops on a Charlotte to Des Moines flight.

How have Charlotte to Des Moines flight prices changed over time?

When to book flights from Charlotte to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Des Moines (CLT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Des Moines

Best Price Found

$421

Fastest flight time

2h 27m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun

Airports in Des Moines

1 airport
The best flight deal from Charlotte to Des Moines found on momondo in the last 72 hours is $421
The fastest flight from Charlotte to Des Moines takes 2h 27m
Direct flights go from Charlotte to Des Moines on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Des Moines. From Charlotte there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from Charlotte to Des Moines

  • How far is Charlotte Douglas to Des Moines by plane?

    Charlotte Douglas and Des Moines are 818.0 mi apart from one another. Flights usually cover this in 2h 27m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Des Moines Airport?

    Prices for flights from Charlotte Douglas Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Des Moines Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charlotte Douglas Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Charlotte to Des Moines?

  • What is the most popular airline from Charlotte to Des Moines?

Best airlines flying from Charlotte to Des Moines

Compare and see reviews for airlines that fly from Charlotte to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $349Free CancellationRating
7.1
11,681 reviews
Search American Airlines flights

  • American Airlines Flights From Charlotte to Des Moines

    American Airlines flight deals from Charlotte to Des Moines start from $349 round-trip. Over the 8 American Airlines flights for this route in a normal week, average airfare is usually $448 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Charlotte.

Can I find flights from Charlotte to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Charlotte which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charlotte to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Charlotte.

I’m not ready to book a flight from Charlotte to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charlotte to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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