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Cheap flights from Charlotte to Des Moines from $143

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Des Moines departing on 7/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charlotte to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 9:33 am
CLT
-
DSM
4h 33m
1 stop
Delta Logo
6:54 pm - 11:59 pm
DSM
-
CLT
4h 05m
1 stop
$287Delta
Fri, Oct 2 - Mon, Oct 5
Multiple Airlines Logo
8:28 pm - 9:32 pm
CLT
-
DSM
26h 04m
2 stops
Multiple Airlines Logo
4:40 pm - 9:07 pm
DSM
-
CLT
27h 27m
1 stop
$305Multiple Airlines
Wed, Jul 8 - Fri, Jul 17
Multiple Airlines Logo
10:02 pm - 9:32 pm
CLT
-
DSM
24h 30m
1 stop
Multiple Airlines Logo
4:40 pm - 9:07 pm
DSM
-
CLT
27h 27m
1 stop
$310Multiple Airlines
Wed, Jul 8 - Fri, Jul 17
Multiple Airlines Logo
10:02 pm - 10:47 pm
CLT
-
DSM
25h 45m
1 stop
Multiple Airlines Logo
4:40 pm - 9:07 pm
DSM
-
CLT
27h 27m
1 stop
$313Multiple Airlines
Sat, Jul 11 - Fri, Jul 17
Southwest Logo
8:10 am - 11:25 am
CLT
-
DSM
4h 15m
1 stop
Southwest Logo
2:40 pm - 9:10 pm
DSM
-
CLT
5h 30m
1 stop
$324Southwest
Thu, Aug 6 - Wed, Aug 12
Southwest Logo
3:10 pm - 10:05 pm
CLT
-
DSM
7h 55m
2 stops
Southwest Logo
12:45 pm - 6:30 pm
DSM
-
CLT
4h 45m
1 stop
$326Southwest
Tue, Dec 1 - Sat, Dec 12
Southwest Logo
8:10 am - 11:25 am
CLT
-
DSM
4h 15m
1 stop
Southwest Logo
2:40 pm - 9:10 pm
DSM
-
CLT
5h 30m
1 stop
$327Southwest
Mon, Aug 10 - Wed, Aug 12
Multiple Airlines Logo
10:51 am - 9:32 pm
CLT
-
DSM
11h 41m
1 stop
Multiple Airlines Logo
4:40 pm - 9:07 pm
DSM
-
CLT
27h 27m
1 stop
$328Multiple Airlines
Thu, Jul 9 - Fri, Jul 17
Multiple Airlines Logo
10:59 pm - 3:24 pm
CLT
-
DSM
17h 25m
1 stop
Multiple Airlines Logo
4:40 pm - 9:07 pm
DSM
-
CLT
27h 27m
1 stop
$330Multiple Airlines
Mon, Jul 13 - Fri, Jul 17
Southwest Logo
3:10 pm - 10:05 pm
CLT
-
DSM
7h 55m
2 stops
Southwest Logo
5:20 am - 7:00 pm
DSM
-
CLT
12h 40m
2 stops
$331Southwest
Tue, Dec 1 - Sat, Dec 12

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Delta flights from Charlotte to Des Moines

Our best Delta deals on Charlotte to Des Moines flight tickets
Delta
Oct 2
CLT6:00 amCharlotte Douglas
4h 33m
1 stop
DSM9:33 amDes Moines
Oct 5
DSM6:54 pmDes Moines
4h 05m
1 stop
CLT11:59 pmCharlotte Douglas
$287
Delta
Jul 8
CLT12:16 pmCharlotte Douglas
6h 36m
1 stop
DSM5:52 pmDes Moines
Jul 15
DSM6:00 amDes Moines
5h 24m
1 stop
CLT12:24 pmCharlotte Douglas
$465
Delta
Jul 3
CLT9:42 amCharlotte Douglas
7h 15m
1 stop
DSM3:57 pmDes Moines
Jul 6
DSM6:39 pmDes Moines
4h 20m
1 stop
CLT11:59 pmCharlotte Douglas
$473

American Airlines flights from Charlotte to Des Moines

Our best American Airlines deals on Charlotte to Des Moines flight tickets
American Airlines
Dec 1
CLT10:35 pmCharlotte Douglas
2h 46m
DSM12:21 amDes Moines
Dec 12
DSM6:40 amDes Moines
2h 45m
CLT10:25 amCharlotte Douglas
$391
American Airlines
Jul 8
CLT11:31 amCharlotte Douglas
2h 25m
DSM12:56 pmDes Moines
Jul 11
DSM7:04 amDes Moines
2h 26m
CLT10:30 amCharlotte Douglas
$445
American Airlines
Jul 8
CLT6:00 pmCharlotte Douglas
2h 30m
DSM7:30 pmDes Moines
Jul 11
DSM1:34 pmDes Moines
6h 16m
1 stop
CLT8:50 pmCharlotte Douglas
$455

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from Charlotte to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 10/2

6:00 am-9:33 am

1 stop4h 33m

Des Moines

Mon 10/5

6:54 pm-11:59 pm

1 stop4h 05m

$287

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 7/8

8:28 pm-9:32 pm

2 stops26h 04m

Des Moines

Fri 7/17

4:40 pm-9:07 pm

1 stop27h 27m

$305

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 7/8

10:02 pm-9:32 pm

1 stop24h 30m

Des Moines

Fri 7/17

4:40 pm-9:07 pm

1 stop27h 27m

$310

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sat 7/11

10:02 pm-10:47 pm

1 stop25h 45m

Des Moines

Fri 7/17

4:40 pm-9:07 pm

1 stop27h 27m

$313

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 8/6

8:10 am-11:25 am

1 stop4h 15m

Des Moines

Wed 8/12

2:40 pm-9:10 pm

1 stop5h 30m

$324

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 12/1

3:10 pm-10:05 pm

2 stops7h 55m

Des Moines

Sat 12/12

12:45 pm-6:30 pm

1 stop4h 45m

$326

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 8/10

8:10 am-11:25 am

1 stop4h 15m

Des Moines

Wed 8/12

2:40 pm-9:10 pm

1 stop5h 30m

$327

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 7/9

10:51 am-9:32 pm

1 stop11h 41m

Des Moines

Fri 7/17

4:40 pm-9:07 pm

1 stop27h 27m

$328

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 7/13

10:59 pm-3:24 pm

1 stop17h 25m

Des Moines

Fri 7/17

4:40 pm-9:07 pm

1 stop27h 27m

$330

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 12/1

3:10 pm-10:05 pm

2 stops7h 55m

Des Moines

Sat 12/12

5:20 am-7:00 pm

2 stops12h 40m

$331

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Charlotte to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charlotte and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then December is your next best option. Flight prices from Charlotte to Des Moines during December average around $421.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Charlotte to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $430. Flights from Charlotte to Des Moines on a Sunday will generally be more expensive and average around $547. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Charlotte to Des Moines in the afternoon for as low as $421. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $467. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Charlotte Douglas to Des Moines flight route?

Fly from Charlotte Douglas to Des Moines for the best Charlotte Douglas - Des Moines flight prices

What cabin class options are available on Charlotte to Des Moines flights?

There are 2 cabin classes available to choose from on Charlotte to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Charlotte to Des Moines flights?

You could potentially save up to 30% on your flight if you consider stops on a Charlotte to Des Moines flight.

How have Charlotte to Des Moines flight prices changed over time?

When to book flights from Charlotte to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Des Moines (CLT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Des Moines

Best Price Found

$471

Fastest flight time

2h 25m

Direct flights

Every day

Airports in Des Moines

1 airport
The best flight deal from Charlotte to Des Moines found on momondo in the last 72 hours is $471
The fastest flight from Charlotte to Des Moines takes 2h 25m
Direct flights go from Charlotte to Des Moines every day.
There is 1 airport in Des Moines. From Charlotte there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from Charlotte to Des Moines

  • How far is Charlotte Douglas to Des Moines by plane?

    Charlotte Douglas and Des Moines are 818.0 mi apart from one another. Flights usually cover this in 2h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Des Moines Airport?

    Prices for flights from Charlotte Douglas Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Des Moines Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charlotte Douglas Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Charlotte to Des Moines?

  • What is the most popular airline from Charlotte to Des Moines?

Best airlines flying from Charlotte to Des Moines

Compare and see reviews for airlines that fly from Charlotte to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $349Free CancellationRating
7.1
11,777 reviews
Search American Airlines flights

  • American Airlines Flights From Charlotte to Des Moines

    American Airlines flight deals from Charlotte to Des Moines start from $349 round-trip. Over the 14 American Airlines flights for this route in a normal week, average airfare is usually $449 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Charlotte.

Can I find flights from Charlotte to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Charlotte which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charlotte to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Charlotte.

I’m not ready to book a flight from Charlotte to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charlotte to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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