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Cheap flights from Charlotte to Des Moines from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Des Moines departing on 2/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charlotte to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
5:13 pm - 6:32 pm
CLT
-
DSM
26h 19m1 stop
Frontier Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$165Frontier
Sun, Feb 22 - Sun, Mar 1
Frontier Logo
5:13 pm - 6:32 pm
CLT
-
DSM
26h 19m1 stop
Frontier Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$171Frontier
Sun, Feb 15 - Sun, Mar 1
Multiple Airlines Logo
5:13 pm - 6:19 pm
CLT
-
DSM
26h 06m1 stop
Multiple Airlines Logo
7:17 pm - 10:17 am
DSM
-
CLT
14h 00m2 stops
$203Multiple Airlines
Thu, Feb 19 - Mon, Feb 23
Multiple Airlines Logo
2:46 pm - 2:19 pm
CLT
-
DSM
48h 33m2 stops
Multiple Airlines Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$215Multiple Airlines
Tue, Feb 10 - Sun, Mar 1
Multiple Airlines Logo
6:01 pm - 7:48 pm
CLT
-
DSM
50h 47m2 stops
Multiple Airlines Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$217Multiple Airlines
Wed, Feb 11 - Sun, Mar 1
Multiple Airlines Logo
2:46 pm - 1:09 pm
CLT
-
DSM
23h 23m1 stop
Multiple Airlines Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$218Multiple Airlines
Tue, Feb 10 - Sun, Mar 1
Multiple Airlines Logo
1:17 pm - 9:39 am
CLT
-
DSM
21h 22m1 stop
Multiple Airlines Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$222Multiple Airlines
Thu, Feb 12 - Sun, Mar 1
Frontier Logo
2:01 pm - 6:19 pm
CLT
-
DSM
29h 18m2 stops
Frontier Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$223Frontier
Thu, Feb 12 - Sun, Mar 1
Multiple Airlines Logo
7:43 pm - 11:12 pm
CLT
-
DSM
28h 29m1 stop
Multiple Airlines Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$225Multiple Airlines
Wed, Feb 11 - Sun, Mar 1
Multiple Airlines Logo
10:20 pm - 9:25 am
CLT
-
DSM
12h 05m1 stop
Multiple Airlines Logo
7:27 pm - 4:18 pm
DSM
-
CLT
19h 51m1 stop
$227Multiple Airlines
Fri, Feb 13 - Sun, Mar 1

Frontier flights from Charlotte to Des Moines

Our best Frontier deals on Charlotte to Des Moines flight tickets
Frontier
Feb 22
CLT5:13 pmCharlotte Douglas
26h 19m
1 stop
DSM6:32 pmDes Moines
Mar 1
DSM7:27 pmDes Moines
19h 51m
1 stop
CLT4:18 pmCharlotte Douglas
$165
Frontier
Feb 15
CLT5:13 pmCharlotte Douglas
26h 19m
1 stop
DSM6:32 pmDes Moines
Mar 1
DSM7:27 pmDes Moines
19h 51m
1 stop
CLT4:18 pmCharlotte Douglas
$171
Frontier
Feb 12
CLT2:01 pmCharlotte Douglas
29h 18m
2 stops
DSM6:19 pmDes Moines
Mar 1
DSM7:27 pmDes Moines
19h 51m
1 stop
CLT4:18 pmCharlotte Douglas
$223

Southwest flights from Charlotte to Des Moines

Our best Southwest deals on Charlotte to Des Moines flight tickets
Southwest
Mar 4
CLT8:25 amCharlotte Douglas
4h 00m
1 stop
DSM11:25 amDes Moines
Mar 6
DSM4:20 pmDes Moines
5h 05m
1 stop
CLT10:25 pmCharlotte Douglas
$336
Southwest
Mar 4
CLT11:05 amCharlotte Douglas
11h 05m
2 stops
DSM9:10 pmDes Moines
Mar 6
DSM6:50 amDes Moines
12h 10m
2 stops
CLT8:00 pmCharlotte Douglas
$352
Southwest
Jan 26
CLT8:25 amCharlotte Douglas
4h 00m
1 stop
DSM11:25 amDes Moines
Jan 28
DSM8:35 amDes Moines
8h 55m
1 stop
CLT6:30 pmCharlotte Douglas
$357

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Charlotte to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 2/22

5:13 pm-6:32 pm

1 stop26h 19m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$165

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 2/15

5:13 pm-6:32 pm

1 stop26h 19m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$171

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 2/19

5:13 pm-6:19 pm

1 stop26h 06m

Des Moines

Mon 2/23

7:17 pm-10:17 am

2 stops14h 00m

$203

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 2/10

2:46 pm-2:19 pm

2 stops48h 33m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$215

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 2/11

6:01 pm-7:48 pm

2 stops50h 47m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$217

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 2/10

2:46 pm-1:09 pm

1 stop23h 23m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$218

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 2/12

1:17 pm-9:39 am

1 stop21h 22m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$222

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 2/12

2:01 pm-6:19 pm

2 stops29h 18m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$223

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 2/11

7:43 pm-11:12 pm

1 stop28h 29m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$225

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 2/13

10:20 pm-9:25 am

1 stop12h 05m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$227

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Charlotte to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charlotte and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in March, then September is your next best option. Flight prices from Charlotte to Des Moines during September average around $342.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Charlotte to Des Moines is on a Sunday. Travelers who choose to depart for Des Moines on a Sunday will often find tickets for as low as $410. Flights from Charlotte to Des Moines on a Saturday will generally be more expensive and average around $462. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Charlotte to Des Moines in the afternoon for as low as $406. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $452. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Charlotte Douglas to Des Moines flight route?

Fly from Charlotte Douglas to Des Moines for the best Charlotte Douglas - Des Moines flight prices

How far in advance should I book a flight to Des Moines?

You are more likely to see cheaper flights to Des Moines from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $421 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from Charlotte for as low as $254 on momondo.

What cabin class options are available on Charlotte Douglas to Des Moines flights?

There is only 1 cabin class available to choose from on Charlotte Douglas to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Charlotte to Des Moines flights?

You could potentially save up to 68% on your flight if you consider stops on a Charlotte to Des Moines flight.

How have Charlotte to Des Moines flight prices changed over time?

When to book flights from Charlotte to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Des Moines (CLT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Des Moines

Fastest flight time

2h 30m

Direct flights

Every day

Airports in Des Moines

1 airport
The fastest flight from Charlotte to Des Moines takes 2h 30m
Direct flights go from Charlotte to Des Moines every day.
There is 1 airport in Des Moines. From Charlotte there are direct flights to Des Moines (DSM).
Search flight deals

  • How far is Charlotte Douglas to Des Moines by plane?

    Charlotte Douglas and Des Moines are 818.0 mi apart from one another. Flights usually cover this in 2h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Des Moines Airport?

    Prices for flights from Charlotte Douglas Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Des Moines Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charlotte Douglas Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Charlotte to Des Moines?

  • What is the most popular airline from Charlotte to Des Moines?

Best airlines flying from Charlotte to Des Moines

Compare and see reviews for airlines that fly from Charlotte to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $232Free CancellationRating
7.9
8,025 reviews
Search Delta flights
American AirlinesPriceFrom $257Free CancellationRating
7.2
11,094 reviews
Search American Airlines flights

  • American Airlines Flights From Charlotte to Des Moines

    American Airlines flight deals from Charlotte to Des Moines start from $257 round-trip. Over the 11 American Airlines flights for this route in a normal week, average airfare is usually $435 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Charlotte.

Can I find flights from Charlotte to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Charlotte which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charlotte to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Charlotte.

I’m not ready to book a flight from Charlotte to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charlotte to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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