What airlines fly to South America?

LATAM Airlines, Delta and United Airlines are the top three most popular airlines that fly to South America from Buffalo according to our data. LATAM Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 5 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Buffalo to South America?

Delta, JetBlue, and American Airlines are the most popular carriers operating from Buffalo to South America

When did momondo last update prices for flights from Buffalo Airport to South America?

Prices for flights from Buffalo Airport to South America refresh daily.

How many operators does momondo search for flights from Buffalo Airport to South America?

There are 4 operators available for flights from Buffalo Airport to South America as of August 2026.

How old do you have to be to fly from Buffalo Airport to South America?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$174 Cheap Flights from Buffalo to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 8:15 pmBUF Buffalo-MDE Medellín Jose Maria Cordova Intl

15h 15m2 stops Washington, D.C. Reagan-National Miami

6:00 am - 10:50 pmMDE Medellín Jose Maria Cordova Intl-BUF Buffalo

15h 50m2 stops Miami Charlotte Douglas

$384American Airlines

Sat, Oct 17 - Sun, Oct 25

7:00 am - 8:15 pmBUF Buffalo-MDE Medellín Jose Maria Cordova Intl

14h 15m2 stops Philadelphia Miami

6:00 am - 10:24 pmMDE Medellín Jose Maria Cordova Intl-BUF Buffalo

15h 24m2 stops Miami New York LaGuardia

$386American Airlines

Sat, Oct 17 - Sun, Oct 25

7:34 pm - 12:35 pmBUF Buffalo-CTG Cartagena Rafael Nunez

18h 01m2 stops Philadelphia Miami

1:35 pm - 10:48 amCTG Cartagena Rafael Nunez-BUF Buffalo

20h 13m2 stops Miami Charlotte Douglas

$388American Airlines

Thu, Oct 1 - Thu, Oct 8

6:00 am - 1:19 pmBUF Buffalo-CTG Cartagena Rafael Nunez

8h 19m1 stop New York John F Kennedy Intl

12:35 pm - 12:02 amCTG Cartagena Rafael Nunez-BUF Buffalo

10h 27m1 stop Fort Lauderdale

$488JetBlue

Mon, Oct 26 - Thu, Oct 29

6:30 am - 11:00 pmBUF Buffalo-CTG Cartagena Rafael Nunez

17h 30m2 stops Newark Panama City Tocumen Intl

9:45 am - 11:11 pmCTG Cartagena Rafael Nunez-BUF Buffalo

36h 26m2 stops Panama City Tocumen Intl Newark

$532United Airlines

Tue, Sep 29 - Tue, Oct 6

5:50 pm - 2:50 pmBUF Buffalo-CTG Cartagena Rafael Nunez

45h 00m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

4:00 pm - 3:16 pmCTG Cartagena Rafael Nunez-BUF Buffalo

23h 16m2 stops Washington, D.C. Dulles Intl Newark

$579United Airlines

Thu, Feb 11 - Tue, Feb 16

6:00 am - 7:30 pmBUF Buffalo-BOG Bogotá El Dorado

13h 30m1 stop Atlanta Hartsfield-Jackson

9:00 am - 11:59 pmBOG Bogotá El Dorado-BUF Buffalo

14h 59m1 stop Atlanta Hartsfield-Jackson

$605LATAM Airlines

Sun, Nov 8 - Wed, Nov 11

7:49 pm - 5:55 pmBUF Buffalo-BOG Bogotá El Dorado

22h 06m2 stops New York John F Kennedy Intl Miami

10:45 am - 11:59 pmBOG Bogotá El Dorado-BUF Buffalo

13h 14m2 stops Miami Atlanta Hartsfield-Jackson

$610LATAM Airlines

Sun, Nov 8 - Wed, Nov 11

6:05 am - 1:40 pmBUF Buffalo-BOG Bogotá El Dorado

8h 35m1 stop Atlanta Hartsfield-Jackson

2:55 pm - 1:29 pmBOG Bogotá El Dorado-BUF Buffalo

21h 34m2 stops Atlanta Hartsfield-Jackson New York LaGuardia

$653Delta

Tue, Sep 29 - Tue, Oct 6

6:59 pm - 1:40 pmBUF Buffalo-BOG Bogotá El Dorado

19h 41m1 stop Atlanta Hartsfield-Jackson

9:00 am - 11:59 pmBOG Bogotá El Dorado-BUF Buffalo

13h 59m1 stop Atlanta Hartsfield-Jackson

$654Delta

Thu, Oct 1 - Thu, Oct 8

Cheap last minute flights

Enter your travel dates to find the best prices.

6:55 am - 7:05 amBUF Buffalo-MDE Medellín Jose Maria Cordova Intl

49h 10m2 stops New York John F Kennedy Intl Pereira Matecana

2:10 pm - 8:10 amMDE Medellín Jose Maria Cordova Intl-BUF Buffalo

17h 00m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$670Multiple Airlines

Sat, Aug 22 - Mon, Sep 14

10:01 am - 10:35 pmBUF Buffalo-MDE Medellín Jose Maria Cordova Intl

13h 34m2 stops Orlando Bogotá El Dorado

5:50 am - 8:41 pmMDE Medellín Jose Maria Cordova Intl-BUF Buffalo

13h 51m2 stops Bogotá El Dorado Orlando

$913Multiple Airlines

Sun, Aug 23 - Wed, Aug 26

6:55 am - 5:25 amBUF Buffalo-MDE Medellín Jose Maria Cordova Intl

23h 30m1 stop New York John F Kennedy Intl

10:55 am - 6:55 pmMDE Medellín Jose Maria Cordova Intl-BUF Buffalo

31h 00m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$936Multiple Airlines

Sun, Aug 23 - Wed, Aug 26

6:55 am - 5:25 amBUF Buffalo-MDE Medellín Jose Maria Cordova Intl

23h 30m1 stop New York John F Kennedy Intl

11:30 am - 11:07 pmMDE Medellín Jose Maria Cordova Intl-BUF Buffalo

10h 37m1 stop San Juan Luis Munoz Marin Intl

$968Multiple Airlines

Sun, Aug 23 - Wed, Aug 26

6:05 am - 10:35 pmBUF Buffalo-MDE Medellín Jose Maria Cordova Intl

17h 30m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

1:30 pm - 10:56 pmMDE Medellín Jose Maria Cordova Intl-BUF Buffalo

8h 26m1 stop Fort Lauderdale

$1,144Multiple Airlines

Sat, Aug 22 - Mon, Sep 14

6:05 am - 3:00 pmBUF Buffalo-SCL Santiago Arturo Merino Benitez

32h 55m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

4:30 pm - 11:59 pmSCL Santiago Arturo Merino Benitez-BUF Buffalo

31h 29m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,147LATAM Airlines

Fri, Aug 21 - Fri, Aug 28

6:05 am - 3:00 pmBUF Buffalo-SCL Santiago Arturo Merino Benitez

32h 55m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

11:05 pm - 11:59 pmSCL Santiago Arturo Merino Benitez-BUF Buffalo

24h 54m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,147LATAM Airlines

Fri, Aug 21 - Fri, Aug 28

6:05 am - 6:55 amBUF Buffalo-SCL Santiago Arturo Merino Benitez

24h 50m2 stops Atlanta Hartsfield-Jackson Miami

8:40 am - 3:13 pmSCL Santiago Arturo Merino Benitez-BUF Buffalo

30h 33m3 stops Punta Cana Miami New York John F Kennedy Intl

$1,152LATAM Airlines

Fri, Aug 21 - Fri, Aug 28

10:00 am - 1:25 pmBUF Buffalo-SCL Santiago Arturo Merino Benitez

27h 25m3 stops New York John F Kennedy Intl Miami Buenos Aires Ministro Pistarini

8:40 am - 3:13 pmSCL Santiago Arturo Merino Benitez-BUF Buffalo

30h 33m3 stops Punta Cana Miami New York John F Kennedy Intl

$1,152LATAM Airlines

Fri, Aug 21 - Fri, Aug 28

6:27 am - 5:40 amBUF Buffalo-GRU Sao Paulo Guarulhos Intl

22h 13m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

11:30 pm - 4:05 pmGRU Sao Paulo Guarulhos Intl-BUF Buffalo

17h 35m2 stops Miami Atlanta Hartsfield-Jackson

$1,402Delta

Fri, Aug 21 - Fri, Aug 28

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Delta flights from Buffalo to South America

Our best Delta deals on Buffalo to South America flight tickets

Delta

Sep 29

BUF6:05 amBuffalo

8h 35m

1 stop

BOG1:40 pmBogotá El Dorado

Oct 6

BOG2:55 pmBogotá El Dorado

21h 34m

2 stops

BUF1:29 pmBuffalo

$653

Delta

Oct 1

BUF6:59 pmBuffalo

19h 41m

1 stop

BOG1:40 pmBogotá El Dorado

Oct 8

BOG9:00 amBogotá El Dorado

13h 59m

1 stop

BUF11:59 pmBuffalo

$654

Delta

Sep 30

BUF6:59 pmBuffalo

19h 16m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Oct 7

CTG5:35 amCartagena Rafael Nunez

17h 24m

2 stops

BUF11:59 pmBuffalo

$689

United Airlines flights from Buffalo to South America

Our best United Airlines deals on Buffalo to South America flight tickets

United Airlines

Sep 29

BUF6:30 amBuffalo

17h 30m

2 stops

CTG11:00 pmCartagena Rafael Nunez

Oct 6

CTG9:45 amCartagena Rafael Nunez

36h 26m

2 stops

BUF11:11 pmBuffalo

$532

United Airlines

Feb 11

BUF5:50 pmBuffalo

45h 00m

2 stops

CTG2:50 pmCartagena Rafael Nunez

Feb 16

CTG4:00 pmCartagena Rafael Nunez

23h 16m

2 stops

BUF3:16 pmBuffalo

$579

United Airlines

Nov 8

BUF6:00 amBuffalo

17h 05m

1 stop

BOG11:05 pmBogotá El Dorado

Nov 11

BOG9:48 amBogotá El Dorado

13h 11m

1 stop

BUF10:59 pmBuffalo

$615

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloMedellín

BUF Buffalo - MDE Medellín Jose Maria Cordova Intl

BUFMDE

Buffalo

Sat 10/17

6:00 am-8:15 pm

2 stops15h 15m

Medellín Jose Maria Cordova Intl

Sun 10/25

6:00 am-10:50 pm

2 stops15h 50m

$384

BuffaloMedellín

BUF Buffalo - MDE Medellín Jose Maria Cordova Intl

BUFMDE

Buffalo

Sat 10/17

7:00 am-8:15 pm

2 stops14h 15m

Medellín Jose Maria Cordova Intl

Sun 10/25

6:00 am-10:24 pm

2 stops15h 24m

$386

BuffaloCartagena

BUF Buffalo - CTG Cartagena Rafael Nunez

BUFCTG

Buffalo

Thu 10/1

7:34 pm-12:35 pm

2 stops18h 01m

Cartagena Rafael Nunez

Thu 10/8

1:35 pm-10:48 am

2 stops20h 13m

$388

Quickest round-trip

BuffaloCartagena

BUF Buffalo - CTG Cartagena Rafael Nunez

BUFCTG

Buffalo

Mon 10/26

6:00 am-1:19 pm

1 stop8h 19m

Cartagena Rafael Nunez

Thu 10/29

12:35 pm-12:02 am

1 stop10h 27m

$488

BuffaloCartagena

BUF Buffalo - CTG Cartagena Rafael Nunez

BUFCTG

Buffalo

Tue 9/29

6:30 am-11:00 pm

2 stops17h 30m

Cartagena Rafael Nunez

Tue 10/6

9:45 am-11:11 pm

2 stops36h 26m

$532

BuffaloCartagena

BUF Buffalo - CTG Cartagena Rafael Nunez

BUFCTG

Buffalo

Thu 2/11

5:50 pm-2:50 pm

2 stops45h 00m

Cartagena Rafael Nunez

Tue 2/16

4:00 pm-3:16 pm

2 stops23h 16m

$579

BuffaloBogotá

BUF Buffalo - BOG Bogotá El Dorado

BUFBOG

Buffalo

Sun 11/8

6:00 am-7:30 pm

1 stop13h 30m

Bogotá El Dorado

Wed 11/11

9:00 am-11:59 pm

1 stop14h 59m

$605

BuffaloBogotá

BUF Buffalo - BOG Bogotá El Dorado

BUFBOG

Buffalo

Sun 11/8

7:49 pm-5:55 pm

2 stops22h 06m

Bogotá El Dorado

Wed 11/11

10:45 am-11:59 pm

2 stops13h 14m

$610

BuffaloBogotá

BUF Buffalo - BOG Bogotá El Dorado

BUFBOG

Buffalo

Tue 9/29

6:05 am-1:40 pm

1 stop8h 35m

Bogotá El Dorado

Tue 10/6

2:55 pm-1:29 pm

2 stops21h 34m

$653

BuffaloBogotá

BUF Buffalo - BOG Bogotá El Dorado

BUFBOG

Buffalo

Thu 10/1

6:59 pm-1:40 pm

1 stop19h 41m

Bogotá El Dorado

Thu 10/8

9:00 am-11:59 pm

1 stop13h 59m

$654

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, June is the cheapest month to fly from Buffalo to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of June, then book flights to South America from Buffalo during April instead. Flights to South America in April, while not as cheap as those in June, still average around $0.

Can stopping save me money on Buffalo to South America flights?

You could potentially save up to 63% on your flight if you consider stops on a Buffalo to South America flight.

Cheap Buffalo to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to South America

Best Price Found	$174
Fastest flight time	7h 19m
Direct flights	None

The best one-way flight to South America from Buffalo in the past 72 hours is $174. The best round-trip flight deal from Buffalo to South America found on momondo in the last 72 hours is $384.

The fastest flight from Buffalo to South America takes 7h 19m

There are no direct flights from Buffalo to South America. There are no popular flight routes from Buffalo to South America.

Search flight deals

Frequently asked questions about flying from Buffalo to South America

When did momondo last update prices for flights from Buffalo Airport to South America?
Prices for flights from Buffalo Airport to South America refresh daily.
How many operators does momondo search for flights from Buffalo Airport to South America?
There are 4 operators available for flights from Buffalo Airport to South America as of August 2026.
How old do you have to be to fly from Buffalo Airport to South America?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Buffalo to South America

Compare and see reviews for airlines that fly from Buffalo to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $320	Free Cancellation	Rating 7.8 8,508 reviews	Search Delta flights
JetBlue	PriceFrom $442	Free Cancellation	Rating 7.1 3,038 reviews	Search JetBlue flights
LATAM Airlines	PriceFrom $587	Free Cancellation	Rating 7.4 1,989 reviews	Search LATAM Airlines flights
United Airlines	PriceFrom $1,163	Free Cancellation	Rating 7.4 10,102 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to South America?

Finding the right flight to South America from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Buffalo to South America with flexible booking policies on momondo?

Flights from Buffalo to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to South America?

momondo provides multiple filters to help you find the best flight to South America from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Buffalo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.