What is the cheapest airline that flies from Buffalo to South America?

United Airlines, American Airlines, and LATAM Airlines are the most popular carriers operating from Buffalo to South America

What airlines fly to South America?

LATAM Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to South America from Buffalo according to our data. LATAM Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 3 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Buffalo Airport to South America?

Prices for flights from Buffalo Airport to South America refresh daily.

How many operators does momondo search for flights from Buffalo Airport to South America?

There are 2 operators available for flights from Buffalo Airport to South America as of March 2026.

How old do you have to be to fly from Buffalo Airport to South America?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$240 Cheap Flights from Buffalo to South America in 2026

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Find the cheapest flights from Buffalo to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:32 pm - 12:48 pm

BUF

MDE

20h 16m

2 stops

1:53 pm - 10:51 am

MDE

BUF

19h 58m

2 stops

$389American Airlines

木, 5月 7 - 木, 5月 14

12:49 pm - 11:50 pm

BUF

MDE

12h 01m

2 stops

1:53 pm - 12:17 pm

MDE

BUF

21h 24m

2 stops

$392American Airlines

火, 5月 26 - 土, 5月 30

11:44 am - 1:00 pm

BUF

MDE

26h 16m

1 stop

1:55 pm - 11:23 am

MDE

BUF

20h 28m

2 stops

$403Multiple Airlines

土, 4月 18 - 木, 4月 23

1:11 pm - 1:00 pm

BUF

MDE

24h 49m

2 stops

1:55 pm - 10:07 am

MDE

BUF

19h 12m

1 stop

$421Multiple Airlines

土, 4月 18 - 木, 4月 23

7:00 am - 1:40 pm

BUF

CTG

7h 40m

1 stop

2:15 pm - 10:00 am

CTG

BUF

18h 45m

2 stops

$435JetBlue

火, 5月 5 - 水, 6月 3

7:00 am - 1:40 pm

BUF

CTG

7h 40m

1 stop

2:15 pm - 9:05 pm

CTG

BUF

29h 50m

1 stop

$444JetBlue

火, 5月 5 - 水, 6月 3

12:09 pm - 10:30 pm

BUF

MDE

11h 21m

2 stops

8:25 am - 11:01 am

MDE

BUF

25h 36m

2 stops

$466LATAM Airlines

月, 4月 20 - 日, 4月 26

12:09 pm - 8:35 am

BUF

CTG

21h 26m

2 stops

7:40 pm - 6:44 pm

CTG

BUF

22h 04m

2 stops

$499LATAM Airlines

日, 5月 3 - 水, 6月 3

7:59 pm - 1:20 pm

BUF

CTG

18h 21m

2 stops

4:25 am - 11:59 pm

CTG

BUF

18h 34m

2 stops

$540Delta

月, 5月 4 - 水, 6月 3

5:12 pm - 9:35 pm

BUF

LIM

29h 23m

2 stops

8:15 am - 11:58 pm

LIM

BUF

14h 43m

2 stops

$798Delta

日, 7月 12 - 木, 8月 13

United Airlines flights from Buffalo to South America

Our best United Airlines deals on Buffalo to South America flight tickets

United Airlines

Apr 19

BUF6:09 amBuffalo

16h 01m

2 stops

MDE9:10 pmMedellín Jose Maria Cordova Intl

Apr 28

MDE9:45 amMedellín Jose Maria Cordova Intl

23h 27m

2 stops

BUF10:12 amBuffalo

$450

United Airlines

Apr 21

BUF7:00 amBuffalo

15h 10m

2 stops

MDE9:10 pmMedellín Jose Maria Cordova Intl

Apr 28

MDE9:45 amMedellín Jose Maria Cordova Intl

12h 48m

2 stops

BUF11:33 pmBuffalo

$487

United Airlines

May 28

BUF5:52 pmBuffalo

28h 18m

2 stops

MDE9:10 pmMedellín Jose Maria Cordova Intl

May 31

MDE9:45 amMedellín Jose Maria Cordova Intl

30h 01m

2 stops

BUF4:46 pmBuffalo

$540

LATAM Airlines flights from Buffalo to South America

Our best LATAM Airlines deals on Buffalo to South America flight tickets

LATAM Airlines

Apr 20

BUF12:09 pmBuffalo

11h 21m

2 stops

MDE10:30 pmMedellín Jose Maria Cordova Intl

Apr 26

MDE8:25 amMedellín Jose Maria Cordova Intl

25h 36m

2 stops

BUF11:01 amBuffalo

$466

LATAM Airlines

Apr 20

BUF7:40 pmBuffalo

26h 30m

2 stops

MDE9:10 pmMedellín Jose Maria Cordova Intl

Apr 27

MDE6:15 pmMedellín Jose Maria Cordova Intl

20h 38m

2 stops

BUF3:53 pmBuffalo

$476

LATAM Airlines

May 3

BUF12:09 pmBuffalo

21h 26m

2 stops

CTG8:35 amCartagena Rafael Nunez

Jun 3

CTG7:40 pmCartagena Rafael Nunez

22h 04m

2 stops

BUF6:44 pmBuffalo

$499

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

木 5/7

5:32 pm-12:48 pm

2 stops20h 16m

Medellín Jose Maria Cordova Intl

木 5/14

1:53 pm-10:51 am

2 stops19h 58m

$389

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

火 5/26

12:49 pm-11:50 pm

2 stops12h 01m

Medellín Jose Maria Cordova Intl

土 5/30

1:53 pm-12:17 pm

2 stops21h 24m

$392

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

土 4/18

11:44 am-1:00 pm

1 stop26h 16m

Medellín Jose Maria Cordova Intl

木 4/23

1:55 pm-11:23 am

2 stops20h 28m

$403

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

土 4/18

1:11 pm-1:00 pm

2 stops24h 49m

Medellín Jose Maria Cordova Intl

木 4/23

1:55 pm-10:07 am

1 stop19h 12m

$421

Quickest round-trip

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

火 5/5

7:00 am-1:40 pm

1 stop7h 40m

Cartagena Rafael Nunez

水 6/3

2:15 pm-10:00 am

2 stops18h 45m

$435

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

火 5/5

7:00 am-1:40 pm

1 stop7h 40m

Cartagena Rafael Nunez

水 6/3

2:15 pm-9:05 pm

1 stop29h 50m

$444

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

月 4/20

12:09 pm-10:30 pm

2 stops11h 21m

Medellín Jose Maria Cordova Intl

日 4/26

8:25 am-11:01 am

2 stops25h 36m

$466

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

日 5/3

12:09 pm-8:35 am

2 stops21h 26m

Cartagena Rafael Nunez

水 6/3

7:40 pm-6:44 pm

2 stops22h 04m

$499

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

月 5/4

7:59 pm-1:20 pm

2 stops18h 21m

Cartagena Rafael Nunez

水 6/3

4:25 am-11:59 pm

2 stops18h 34m

$540

BuffaloLima

BUF - LIM

BUFLIM

Buffalo

日 7/12

5:12 pm-9:35 pm

2 stops29h 23m

Lima J Chavez Intl

木 8/13

8:15 am-11:58 pm

2 stops14h 43m

$798

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Buffalo to South America flights?

You could potentially save up to 63% on your flight if you consider stops on a Buffalo to South America flight.

Cheap Buffalo to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to South America

Fastest flight time	7h 28m
Direct flights	None

The fastest flight from Buffalo to South America takes 7h 28m

There are no direct flights from Buffalo to South America. There are no popular flight routes from Buffalo to South America.

Search flight deals

When did momondo last update prices for flights from Buffalo Airport to South America?
Prices for flights from Buffalo Airport to South America refresh daily.
How many operators does momondo search for flights from Buffalo Airport to South America?
There are 2 operators available for flights from Buffalo Airport to South America as of March 2026.
How old do you have to be to fly from Buffalo Airport to South America?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Buffalo to South America

Compare and see reviews for airlines that fly from Buffalo to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $320	Free Cancellation	Rating 7.9 8,336 reviews		Search Delta flights
LATAM Airlines	PriceFrom $587	Free Cancellation	Rating 7.4 1,904 reviews		Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to South America?

Finding the right flight to South America from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Buffalo to South America with flexible booking policies on momondo?

Flights from Buffalo to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to South America?

momondo provides multiple filters to help you find the best flight to South America from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Buffalo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.