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Cheap flights from Buffalo to South America from $204

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to South America departing on 1/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Buffalo to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:06 pm - 10:55 amBUF-MDE
17h 49m1 stop
Multiple Airlines Logo
2:54 pm - 10:04 amMDE-BUF
19h 10m1 stop
$492Multiple Airlines
Find Deal
Mon, Dec 8 - Thu, Dec 18
Delta Logo
6:25 pm - 1:45 pmBUF-BOG
19h 20m2 stops
Delta Logo
6:15 am - 11:50 pmBOG-BUF
17h 35m2 stops
$495Delta
Find Deal
Tue, Nov 11 - Mon, Nov 24
LATAM Airlines Logo
6:10 am - 7:30 pmBUF-BOG
13h 20m1 stop
LATAM Airlines Logo
10:55 am - 10:41 amBOG-BUF
23h 46m2 stops
$500LATAM Airlines
Find Deal
Mon, Dec 1 - Tue, Dec 2
LATAM Airlines Logo
6:00 am - 7:30 pmBUF-BOG
14h 30m1 stop
LATAM Airlines Logo
2:55 pm - 11:16 amBOG-BUF
19h 21m1 stop
$503LATAM Airlines
Find Deal
Tue, Mar 24 - Fri, Mar 27
JetBlue Logo
5:40 pm - 1:20 pmBUF-MDE
19h 40m1 stop
JetBlue Logo
2:25 pm - 10:50 amMDE-BUF
20h 25m2 stops
$564JetBlue
Find Deal
Sun, Mar 1 - Sat, Mar 7
United Airlines Logo
7:00 am - 10:05 pmBUF-MDE
15h 05m2 stops
United Airlines Logo
10:45 am - 8:45 amMDE-BUF
22h 00m2 stops
$566United Airlines
Find Deal
Sun, Mar 1 - Sat, Mar 7
JetBlue Logo
5:40 pm - 1:20 pmBUF-MDE
19h 40m1 stop
JetBlue Logo
2:25 pm - 11:51 pmMDE-BUF
9h 26m1 stop
$582JetBlue
Find Deal
Sun, Mar 1 - Sat, Mar 7
American Airlines Logo
7:53 pm - 3:01 pmBUF-CTG
19h 08m2 stops
American Airlines Logo
4:50 pm - 10:42 amCTG-BUF
17h 52m2 stops
$614American Airlines
Find Deal
Mon, Feb 16 - Mon, Feb 23
United Airlines Logo
7:07 am - 4:54 amBUF-BOG
22h 47m2 stops
United Airlines Logo
8:15 am - 10:03 amBOG-BUF
25h 48m2 stops
$617United Airlines
Find Deal
Fri, Oct 24 - Sun, Nov 2
American Airlines Logo
6:53 pm - 3:30 pmBUF-CTG
20h 37m2 stops
American Airlines Logo
4:30 pm - 12:08 pmCTG-BUF
19h 38m2 stops
$636American Airlines
Find Deal
Thu, Jan 15 - Mon, Jan 19

Delta flights from Buffalo to South America

Our best Delta deals on Buffalo to South America flight tickets
Delta
Nov 11
BUF6:25 pmBuffalo
19h 20m
2 stops
BOG1:45 pmBogotá El Dorado
Nov 24
BOG6:15 amBogotá El Dorado
17h 35m
2 stops
BUF11:50 pmBuffalo
$495
Find similar
Delta
Jan 8
BUF5:40 pmBuffalo
20h 55m
2 stops
BOG2:35 pmBogotá El Dorado
Jan 17
BOG1:35 amBogotá El Dorado
12h 13m
2 stops
BUF1:48 pmBuffalo
$550
Find similar
Delta
Jan 8
BUF5:40 pmBuffalo
20h 55m
2 stops
BOG2:35 pmBogotá El Dorado
Jan 18
BOG3:55 pmBogotá El Dorado
19h 21m
1 stop
BUF11:16 amBuffalo
$555
Find similar

LATAM Airlines flights from Buffalo to South America

Our best LATAM Airlines deals on Buffalo to South America flight tickets
LATAM Airlines
Dec 1
BUF6:10 amBuffalo
13h 20m
1 stop
BOG7:30 pmBogotá El Dorado
Dec 2
BOG10:55 amBogotá El Dorado
23h 46m
2 stops
BUF10:41 amBuffalo
$500
Find similar
LATAM Airlines
Mar 24
BUF6:00 amBuffalo
14h 30m
1 stop
BOG7:30 pmBogotá El Dorado
Mar 27
BOG2:55 pmBogotá El Dorado
19h 21m
1 stop
BUF11:16 amBuffalo
$503
Find similar
LATAM Airlines
Mar 24
BUF6:00 amBuffalo
13h 40m
2 stops
BOG6:40 pmBogotá El Dorado
Mar 27
BOG2:55 pmBogotá El Dorado
19h 21m
1 stop
BUF11:16 amBuffalo
$507
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Mon 12/8

5:06 pm-10:55 am

1 stop17h 49m

Medellín Jose Maria Cordova Intl

Thu 12/18

2:54 pm-10:04 am

1 stop19h 10m

$492

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Tue 11/11

6:25 pm-1:45 pm

2 stops19h 20m

Bogotá El Dorado

Mon 11/24

6:15 am-11:50 pm

2 stops17h 35m

$495

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Mon 12/1

6:10 am-7:30 pm

1 stop13h 20m

Bogotá El Dorado

Tue 12/2

10:55 am-10:41 am

2 stops23h 46m

$500

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Tue 3/24

6:00 am-7:30 pm

1 stop14h 30m

Bogotá El Dorado

Fri 3/27

2:55 pm-11:16 am

1 stop19h 21m

$503

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Sun 3/1

5:40 pm-1:20 pm

1 stop19h 40m

Medellín Jose Maria Cordova Intl

Sat 3/7

2:25 pm-10:50 am

2 stops20h 25m

$564

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Sun 3/1

7:00 am-10:05 pm

2 stops15h 05m

Medellín Jose Maria Cordova Intl

Sat 3/7

10:45 am-8:45 am

2 stops22h 00m

$566

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Sun 3/1

5:40 pm-1:20 pm

1 stop19h 40m

Medellín Jose Maria Cordova Intl

Sat 3/7

2:25 pm-11:51 pm

1 stop9h 26m

$582

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Mon 2/16

7:53 pm-3:01 pm

2 stops19h 08m

Cartagena Rafael Nunez

Mon 2/23

4:50 pm-10:42 am

2 stops17h 52m

$614

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Fri 10/24

7:07 am-4:54 am

2 stops22h 47m

Bogotá El Dorado

Sun 11/2

8:15 am-10:03 am

2 stops25h 48m

$617

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Thu 1/15

6:53 pm-3:30 pm

2 stops20h 37m

Cartagena Rafael Nunez

Mon 1/19

4:30 pm-12:08 pm

2 stops19h 38m

$636

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Buffalo to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, March is the cheapest month to fly from Buffalo to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $609. If you aren’t able to travel during the month of March, then book flights to South America from Buffalo during November instead. Flights to South America in November, while not as cheap as those in March, still average around $626.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Buffalo to South America is on a Tuesday when prices can be found for as low as $441. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Buffalo to South America for around $1,649.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Buffalo to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $631. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $661 on average. Flights to South America from Buffalo in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Buffalo to South America flights?

You could potentially save up to 32% on your flight if you consider stops on a Buffalo to South America flight.

Cheap Buffalo to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to South America

Direct flights

None
There are no direct flights from Buffalo to South America. There are no popular flight routes from Buffalo to South America.
Search flight deals

  • When did momondo last update prices for flights from Buffalo Airport to South America?

    Prices for flights from Buffalo Airport to South America refresh daily.

  • How many operators does momondo search for flights from Buffalo Airport to South America?

  • How old do you have to be to fly from Buffalo Airport to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Buffalo to South America

Compare and see reviews for airlines that fly from Buffalo to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $451Free CancellationRating
7.9
7,972 reviews
Search Delta flights
LATAM AirlinesPriceFrom $494Free CancellationRating
7.5
1,865 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $757Free CancellationRating
7.4
8,975 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to South America?

Finding the right flight to South America from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Buffalo to South America with flexible booking policies on momondo?

Flights from Buffalo to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to South America?

momondo provides multiple filters to help you find the best flight to South America from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Buffalo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

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Popular flights according to clicks in the last 7 days on momondo
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