What airlines fly to South America?

LATAM Airlines, Delta and United Airlines are the top three most popular airlines that fly to South America from Buffalo according to our data. LATAM Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 5 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Buffalo to South America?

American Airlines, JetBlue, and Copa Airlines are the most popular carriers operating from Buffalo to South America

When did momondo last update prices for flights from Buffalo Airport to South America?

Prices for flights from Buffalo Airport to South America refresh daily.

How many operators does momondo search for flights from Buffalo Airport to South America?

There are 4 operators available for flights from Buffalo Airport to South America as of July 2026.

How old do you have to be to fly from Buffalo Airport to South America?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$148 Cheap Flights from Buffalo to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:58 pm - 9:10 pm

BUF

MDE

28h 12m

2 stops

9:45 am - 9:28 am

MDE

BUF

22h 43m

2 stops

$433Multiple Airlines

Fri, Aug 21 - Wed, Aug 26

5:58 pm - 9:10 pm

BUF

MDE

28h 12m

2 stops

9:45 am - 9:28 am

MDE

BUF

22h 43m

2 stops

$447United Airlines

Sun, Aug 23 - Wed, Aug 26

6:59 pm - 8:15 pm

BUF

MDE

26h 16m

2 stops

6:00 am - 10:18 am

MDE

BUF

27h 18m

2 stops

$517GOL

Thu, Aug 13 - Tue, Aug 18

6:59 pm - 12:48 pm

BUF

MDE

18h 49m

2 stops

6:00 am - 11:36 pm

MDE

BUF

16h 36m

2 stops

$588GOL

Tue, Aug 18 - Wed, Aug 26

7:19 pm - 1:40 pm

BUF

BOG

19h 21m

1 stop

2:55 pm - 11:08 am

BOG

BUF

19h 13m

1 stop

$595LATAM Airlines

Thu, Aug 20 - Tue, Aug 25

6:51 pm - 2:25 pm

BUF

MDE

20h 34m

1 stop

3:30 pm - 11:07 pm

MDE

BUF

30h 37m

1 stop

$600JetBlue

Thu, Aug 13 - Thu, Aug 20

9:15 am - 2:25 pm

BUF

MDE

30h 10m

2 stops

3:30 pm - 11:07 pm

MDE

BUF

30h 37m

1 stop

$606JetBlue

Tue, Aug 18 - Tue, Aug 25

7:15 pm - 6:42 pm

BUF

UIO

23h 27m

2 stops

12:30 pm - 12:33 pm

UIO

BUF

24h 03m

2 stops

$616LATAM Airlines

Sat, Nov 14 - Wed, Nov 18

5:15 pm - 6:59 pm

BUF

UIO

26h 44m

1 stop

12:59 am - 2:53 pm

UIO

BUF

12h 54m

1 stop

$705Delta

Sat, Sep 12 - Mon, Sep 21

5:15 pm - 6:59 pm

BUF

UIO

26h 44m

1 stop

12:59 am - 10:57 pm

UIO

BUF

20h 58m

2 stops

$709Delta

Sat, Sep 12 - Mon, Sep 21

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Delta flights from Buffalo to South America

Our best Delta deals on Buffalo to South America flight tickets

Delta

Sep 3

BUF6:05 amBuffalo

12h 45m

2 stops

BOG5:50 pmBogotá El Dorado

Sep 7

BOG11:00 amBogotá El Dorado

23h 12m

2 stops

BUF11:12 amBuffalo

$619

Delta

Aug 14

BUF6:10 pmBuffalo

20h 30m

2 stops

BOG1:40 pmBogotá El Dorado

Aug 23

BOG8:40 amBogotá El Dorado

14h 18m

2 stops

BUF11:58 pmBuffalo

$622

Delta

Sep 12

BUF5:15 pmBuffalo

26h 44m

1 stop

UIO6:59 pmQuito Mariscal Sucr

Sep 21

UIO12:59 amQuito Mariscal Sucr

12h 54m

1 stop

BUF2:53 pmBuffalo

$705

American Airlines flights from Buffalo to South America

Our best American Airlines deals on Buffalo to South America flight tickets

American Airlines

Oct 21

BUF8:00 amBuffalo

14h 17m

2 stops

BOG9:17 pmBogotá El Dorado

Oct 28

BOG6:30 amBogotá El Dorado

16h 02m

2 stops

BUF11:32 pmBuffalo

$580

American Airlines

Aug 28

BUF6:14 amBuffalo

16h 03m

2 stops

BOG9:17 pmBogotá El Dorado

Sep 8

BOG6:30 amBogotá El Dorado

16h 26m

2 stops

BUF11:56 pmBuffalo

$585

American Airlines

Aug 28

BUF7:00 amBuffalo

16h 34m

1 stop

BOG10:34 pmBogotá El Dorado

Sep 7

BOG12:25 amBogotá El Dorado

21h 36m

1 stop

BUF11:01 pmBuffalo

$591

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Fri 8/21

5:58 pm-9:10 pm

2 stops28h 12m

Medellín Jose Maria Cordova Intl

Wed 8/26

9:45 am-9:28 am

2 stops22h 43m

$433

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Sun 8/23

5:58 pm-9:10 pm

2 stops28h 12m

Medellín Jose Maria Cordova Intl

Wed 8/26

9:45 am-9:28 am

2 stops22h 43m

$447

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Thu 8/13

6:59 pm-8:15 pm

2 stops26h 16m

Medellín Jose Maria Cordova Intl

Tue 8/18

6:00 am-10:18 am

2 stops27h 18m

$517

Quickest round-trip

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Tue 8/18

6:59 pm-12:48 pm

2 stops18h 49m

Medellín Jose Maria Cordova Intl

Wed 8/26

6:00 am-11:36 pm

2 stops16h 36m

$588

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Thu 8/20

7:19 pm-1:40 pm

1 stop19h 21m

Bogotá El Dorado

Tue 8/25

2:55 pm-11:08 am

1 stop19h 13m

$595

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Thu 8/13

6:51 pm-2:25 pm

1 stop20h 34m

Medellín Jose Maria Cordova Intl

Thu 8/20

3:30 pm-11:07 pm

1 stop30h 37m

$600

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Tue 8/18

9:15 am-2:25 pm

2 stops30h 10m

Medellín Jose Maria Cordova Intl

Tue 8/25

3:30 pm-11:07 pm

1 stop30h 37m

$606

BuffaloQuito

BUF - UIO

BUFUIO

Buffalo

Sat 11/14

7:15 pm-6:42 pm

2 stops23h 27m

Quito Mariscal Sucr

Wed 11/18

12:30 pm-12:33 pm

2 stops24h 03m

$616

BuffaloQuito

BUF - UIO

BUFUIO

Buffalo

Sat 9/12

5:15 pm-6:59 pm

1 stop26h 44m

Quito Mariscal Sucr

Mon 9/21

12:59 am-2:53 pm

1 stop12h 54m

$705

BuffaloQuito

BUF - UIO

BUFUIO

Buffalo

Sat 9/12

5:15 pm-6:59 pm

1 stop26h 44m

Quito Mariscal Sucr

Mon 9/21

12:59 am-10:57 pm

2 stops20h 58m

$709

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, June is the cheapest month to fly from Buffalo to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of June, then book flights to South America from Buffalo during April instead. Flights to South America in April, while not as cheap as those in June, still average around $0.

Can stopping save me money on Buffalo to South America flights?

You could potentially save up to 63% on your flight if you consider stops on a Buffalo to South America flight.

Cheap Buffalo to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to South America

Fastest flight time	7h 19m
Direct flights	None

The fastest flight from Buffalo to South America takes 7h 19m

There are no direct flights from Buffalo to South America. There are no popular flight routes from Buffalo to South America.

Search flight deals

Frequently asked questions about flying from Buffalo to South America

When did momondo last update prices for flights from Buffalo Airport to South America?
Prices for flights from Buffalo Airport to South America refresh daily.
How many operators does momondo search for flights from Buffalo Airport to South America?
There are 4 operators available for flights from Buffalo Airport to South America as of July 2026.
How old do you have to be to fly from Buffalo Airport to South America?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Buffalo to South America

Compare and see reviews for airlines that fly from Buffalo to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $320	Free Cancellation	Rating 7.8 8,452 reviews	Search Delta flights
JetBlue	PriceFrom $442	Free Cancellation	Rating 7.1 3,010 reviews	Search JetBlue flights
LATAM Airlines	PriceFrom $587	Free Cancellation	Rating 7.4 1,944 reviews	Search LATAM Airlines flights
United Airlines	PriceFrom $1,163	Free Cancellation	Rating 7.4 9,909 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to South America?

Finding the right flight to South America from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Buffalo to South America with flexible booking policies on momondo?

Flights from Buffalo to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to South America?

momondo provides multiple filters to help you find the best flight to South America from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Buffalo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.