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Cheap flights from Buffalo to Knoxville from $144

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:37 pm - 6:18 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
5h 41m1 stop Washington, D.C. Reagan-National
American Airlines Logo
6:14 am - 12:06 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
5h 52m1 stop Charlotte Douglas
$287American Airlines
Tue, Feb 2 - Sat, Feb 6
Delta Logo
12:06 pm - 6:22 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
6h 16m1 stop Detroit Metropolitan Wayne County
Delta Logo
5:10 pm - 12:01 amTYS  Knoxville McGhee Tyson-BUF Buffalo
6h 51m1 stop Detroit Metropolitan Wayne County
$287Delta
Tue, Dec 1 - Fri, Dec 4
Delta Logo
6:05 am - 11:15 amBUF  Buffalo-TYS Knoxville McGhee Tyson
5h 10m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:15 am - 11:12 amTYS  Knoxville McGhee Tyson-BUF Buffalo
5h 57m1 stop Atlanta Hartsfield-Jackson
$287Delta
Fri, Feb 5 - Mon, Feb 8
Delta Logo
6:00 am - 12:37 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
6h 37m1 stop New York LaGuardia
Delta Logo
7:10 am - 11:41 amTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 31m1 stop Detroit Metropolitan Wayne County
$287Delta
Sat, Feb 20 - Sat, Feb 27
United Airlines Logo
7:03 am - 2:47 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
7h 44m2 stops Newark Washington, D.C. Dulles Intl
United Airlines Logo
12:20 pm - 7:32 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
7h 12m1 stop Newark
$292United Airlines
Fri, Feb 5 - Mon, Feb 8
United Airlines Logo
7:03 am - 2:47 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
7h 44m2 stops Newark Washington, D.C. Dulles Intl
United Airlines Logo
6:30 am - 2:17 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
7h 47m2 stops Newark Washington, D.C. Dulles Intl
$302United Airlines
Fri, Feb 5 - Mon, Feb 8
Southwest Logo
5:45 am - 12:15 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
6h 30m2 stops Baltimore/Washington Nashville Intl
Southwest Logo
7:45 am - 12:00 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 15m1 stop Baltimore/Washington
$316Southwest
Tue, Feb 2 - Sat, Feb 6
Southwest Logo
5:45 am - 12:30 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
6h 45m1 stop Baltimore/Washington
Southwest Logo
1:00 pm - 10:00 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
9h 00m2 stops Orlando Baltimore/Washington
$324Southwest
Thu, Nov 26 - Wed, Dec 2
American Airlines Logo
7:44 pm - 11:59 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
4h 15m1 stop Charlotte Douglas
American Airlines Logo
4:38 pm - 10:39 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
6h 01m1 stop Charlotte Douglas
$437American Airlines
Tue, Dec 1 - Fri, Dec 4
American Airlines Logo
5:56 am - 10:33 amBUF  Buffalo-TYS Knoxville McGhee Tyson
4h 37m1 stop Charlotte Douglas
American Airlines Logo
6:30 am - 10:56 amTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 26m1 stop Philadelphia
$487American Airlines
Tue, Nov 24 - Sun, Dec 27

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Delta flights from Buffalo to Knoxville

Our best Delta deals on Buffalo to Knoxville flight tickets
Delta
Nov 26
BUF3:30 pmBuffalo
6h 42m
1 stop
TYS10:12 pmKnoxville McGhee Tyson
Dec 2
TYS6:17 pmKnoxville McGhee Tyson
5h 47m
1 stop
BUF12:04 amBuffalo
$287
Delta
Dec 9
BUF10:00 amBuffalo
6h 45m
1 stop
TYS4:45 pmKnoxville McGhee Tyson
Dec 13
TYS7:26 pmKnoxville McGhee Tyson
4h 38m
1 stop
BUF12:04 amBuffalo
$319
Delta
Dec 9
BUF10:00 amBuffalo
6h 45m
1 stop
TYS4:45 pmKnoxville McGhee Tyson
Dec 13
TYS7:26 pmKnoxville McGhee Tyson
4h 38m
1 stop
BUF12:04 amBuffalo
$324

United Airlines flights from Buffalo to Knoxville

Our best United Airlines deals on Buffalo to Knoxville flight tickets
United Airlines
Feb 5
BUF7:03 amBuffalo
7h 44m
2 stops
TYS2:47 pmKnoxville McGhee Tyson
Feb 8
TYS12:20 pmKnoxville McGhee Tyson
7h 12m
1 stop
BUF7:32 pmBuffalo
$292
United Airlines
Feb 5
BUF7:03 amBuffalo
7h 44m
2 stops
TYS2:47 pmKnoxville McGhee Tyson
Feb 8
TYS6:30 amKnoxville McGhee Tyson
7h 47m
2 stops
BUF2:17 pmBuffalo
$302
United Airlines
Nov 26
BUF6:00 amBuffalo
5h 30m
1 stop
TYS11:30 amKnoxville McGhee Tyson
Nov 30
TYS7:35 pmKnoxville McGhee Tyson
4h 09m
1 stop
BUF11:44 pmBuffalo
$362

momondo Fare Finder

 
Use the filters below to find and compare flights from Buffalo to Knoxville that are best for you.

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Cheapest round-trip

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Tue 2/2

12:37 pm-6:18 pm

1 stop5h 41m

Knoxville McGhee Tyson

Sat 2/6

6:14 am-12:06 pm

1 stop5h 52m

$287

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Tue 12/1

12:06 pm-6:22 pm

1 stop6h 16m

Knoxville McGhee Tyson

Fri 12/4

5:10 pm-12:01 am

1 stop6h 51m

$287

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Fri 2/5

6:05 am-11:15 am

1 stop5h 10m

Knoxville McGhee Tyson

Mon 2/8

5:15 am-11:12 am

1 stop5h 57m

$287

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Sat 2/20

6:00 am-12:37 pm

1 stop6h 37m

Knoxville McGhee Tyson

Sat 2/27

7:10 am-11:41 am

1 stop4h 31m

$287

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Fri 2/5

7:03 am-2:47 pm

2 stops7h 44m

Knoxville McGhee Tyson

Mon 2/8

12:20 pm-7:32 pm

1 stop7h 12m

$292

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Fri 2/5

7:03 am-2:47 pm

2 stops7h 44m

Knoxville McGhee Tyson

Mon 2/8

6:30 am-2:17 pm

2 stops7h 47m

$302

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Tue 2/2

5:45 am-12:15 pm

2 stops6h 30m

Knoxville McGhee Tyson

Sat 2/6

7:45 am-12:00 pm

1 stop4h 15m

$316

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Thu 11/26

5:45 am-12:30 pm

1 stop6h 45m

Knoxville McGhee Tyson

Wed 12/2

1:00 pm-10:00 pm

2 stops9h 00m

$324

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Tue 12/1

7:44 pm-11:59 pm

1 stop4h 15m

Knoxville McGhee Tyson

Fri 12/4

4:38 pm-10:39 pm

1 stop6h 01m

$437
Quickest round-trip

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Tue 11/24

5:56 am-10:33 am

1 stop4h 37m

Knoxville McGhee Tyson

Sun 12/27

6:30 am-10:56 am

1 stop4h 26m

$487

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Buffalo to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of June is, on average, the cheapest month to fly to Knoxville from Buffalo, with most prices found around $344. If you aren’t able to travel during the month of June, then book flights to Knoxville from Buffalo during November instead. Flights to Knoxville in November, while not as cheap as those in June, still average around $350.

How have Buffalo to Knoxville flight prices changed over time?

When to book flights from Buffalo to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Knoxville (BUF to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Knoxville

Best Price Found

$144

Fastest flight time

3h 49m

Direct flights

None
The best one-way flight to Knoxville from Buffalo in the past 72 hours is $144. The best round-trip flight deal from Buffalo to Knoxville found on momondo in the last 72 hours is $287.
The fastest flight from Buffalo to Knoxville takes 3h 49m
There are no direct flights from Buffalo to Knoxville. There are no popular flight routes from Buffalo to Knoxville.
Search flight deals

Frequently asked questions about flying from Buffalo to Knoxville

  • How far is Buffalo to Knoxville McGhee Tyson by plane?

    The distance between Buffalo and Knoxville McGhee Tyson is about 548.4 mi. By plane, this route typically takes 3h 49m.

  • When did momondo last update prices for flights from Buffalo Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Buffalo Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Buffalo Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Buffalo Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Knoxville?

Best airlines flying from Buffalo to Knoxville

Compare and see reviews for airlines that fly from Buffalo to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $250Free CancellationRating
7.8
8,698 reviews
Search Delta flights
American AirlinesPriceFrom $278Free CancellationRating
7.0
12,228 reviews
Search American Airlines flights
United AirlinesPriceFrom $286Free CancellationRating
7.3
10,469 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Kodak
Oak Ridge
Newport
Lenoir City
Dandridge
Clinton
Rockford
Jefferson City

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Buffalo to Knoxville for you.

Can I find flights from Buffalo to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Buffalo to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Buffalo to Knoxville?

momondo helps you find the best flight between Buffalo and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Buffalo to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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