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Cheap flights from Buffalo to Knoxville from $144

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 11:12 amBUF  Buffalo-TYS Knoxville McGhee Tyson
5h 12m1 stop Philadelphia
American Airlines Logo
12:42 pm - 6:36 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
5h 54m1 stop Philadelphia
$287American Airlines
Thu, Dec 10 - Mon, Dec 14
Delta Logo
12:11 pm - 5:30 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
5h 19m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:25 am - 11:27 amTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 02m1 stop Detroit Metropolitan Wayne County
$287Delta
Thu, Dec 17 - Thu, Dec 24
Delta Logo
6:00 am - 11:28 amBUF  Buffalo-TYS Knoxville McGhee Tyson
5h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:10 am - 11:23 amTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 13m1 stop Detroit Metropolitan Wayne County
$287Delta
Wed, Nov 11 - Sat, Nov 14
Delta Logo
6:00 am - 11:28 amBUF  Buffalo-TYS Knoxville McGhee Tyson
5h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:10 am - 11:23 amTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 13m1 stop Detroit Metropolitan Wayne County
$287Delta
Wed, Nov 11 - Sat, Nov 14
United Airlines Logo
10:35 am - 2:48 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
4h 13m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
1:55 pm - 11:49 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
9h 54m2 stops Washington, D.C. Dulles Intl Newark
$292United Airlines
Wed, Nov 11 - Sat, Nov 14
United Airlines Logo
6:30 am - 2:42 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
8h 12m2 stops Newark Washington, D.C. Dulles Intl
United Airlines Logo
5:45 am - 9:54 amTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 09m1 stop Washington, D.C. Dulles Intl
$292United Airlines
Wed, Oct 21 - Wed, Oct 28
American Airlines Logo
6:00 am - 10:30 amBUF  Buffalo-TYS Knoxville McGhee Tyson
4h 30m1 stop Charlotte Douglas
American Airlines Logo
5:19 pm - 9:40 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 21m1 stop Charlotte Douglas
$301American Airlines
Fri, Dec 11 - Mon, Dec 14
American Airlines Logo
1:11 pm - 8:18 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
7h 07m1 stop Philadelphia
American Airlines Logo
6:10 pm - 11:59 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
5h 49m1 stop Washington, D.C. Reagan-National
$327American Airlines
Thu, Oct 29 - Sun, Nov 1
Southwest Logo
6:00 am - 3:00 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
9h 00m2 stops Baltimore/Washington Dallas Love Field
Southwest Logo
7:55 am - 12:05 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
4h 10m1 stop Baltimore/Washington
$359Southwest
Fri, Dec 11 - Mon, Dec 14
Southwest Logo
8:00 am - 4:40 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
8h 40m2 stops Baltimore/Washington Orlando
Southwest Logo
7:15 am - 3:20 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
8h 05m2 stops Nashville Intl Baltimore/Washington
$370Southwest
Wed, Oct 21 - Wed, Oct 28

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Delta flights from Buffalo to Knoxville

Our best Delta deals on Buffalo to Knoxville flight tickets
Delta
Nov 11
BUF6:00 amBuffalo
5h 28m
1 stop
TYS11:28 amKnoxville McGhee Tyson
Nov 14
TYS7:10 amKnoxville McGhee Tyson
4h 13m
1 stop
BUF11:23 amBuffalo
$287
Delta
Dec 9
BUF10:00 amBuffalo
6h 45m
1 stop
TYS4:45 pmKnoxville McGhee Tyson
Dec 13
TYS7:26 pmKnoxville McGhee Tyson
4h 38m
1 stop
BUF12:04 amBuffalo
$327
Delta
Dec 23
BUF5:50 pmBuffalo
3h 40m
1 stop
TYS9:30 pmKnoxville McGhee Tyson
Dec 25
TYS7:25 amKnoxville McGhee Tyson
4h 02m
1 stop
BUF11:27 amBuffalo
$341

United Airlines flights from Buffalo to Knoxville

Our best United Airlines deals on Buffalo to Knoxville flight tickets
United Airlines
Nov 11
BUF10:35 amBuffalo
4h 13m
1 stop
TYS2:48 pmKnoxville McGhee Tyson
Nov 14
TYS1:55 pmKnoxville McGhee Tyson
9h 54m
2 stops
BUF11:49 pmBuffalo
$292
United Airlines
Nov 12
BUF6:00 amBuffalo
5h 30m
1 stop
TYS11:30 amKnoxville McGhee Tyson
Nov 15
TYS5:45 amKnoxville McGhee Tyson
4h 09m
1 stop
BUF9:54 amBuffalo
$354
United Airlines
Nov 11
BUF6:00 amBuffalo
7h 13m
2 stops
TYS1:13 pmKnoxville McGhee Tyson
Nov 14
TYS6:45 amKnoxville McGhee Tyson
7h 35m
2 stops
BUF2:20 pmBuffalo
$371

momondo Fare Finder

 
Use the filters below to find and compare flights from Buffalo to Knoxville that are best for you.

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Price

Cheapest round-trip

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Thu 12/10

6:00 am-11:12 am

1 stop5h 12m

Knoxville McGhee Tyson

Mon 12/14

12:42 pm-6:36 pm

1 stop5h 54m

$287

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Thu 12/17

12:11 pm-5:30 pm

1 stop5h 19m

Knoxville McGhee Tyson

Thu 12/24

7:25 am-11:27 am

1 stop4h 02m

$287

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Wed 11/11

6:00 am-11:28 am

1 stop5h 28m

Knoxville McGhee Tyson

Sat 11/14

7:10 am-11:23 am

1 stop4h 13m

$287

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Wed 11/11

6:00 am-11:28 am

1 stop5h 28m

Knoxville McGhee Tyson

Sat 11/14

7:10 am-11:23 am

1 stop4h 13m

$287

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Wed 11/11

10:35 am-2:48 pm

1 stop4h 13m

Knoxville McGhee Tyson

Sat 11/14

1:55 pm-11:49 pm

2 stops9h 54m

$292

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Wed 10/21

6:30 am-2:42 pm

2 stops8h 12m

Knoxville McGhee Tyson

Wed 10/28

5:45 am-9:54 am

1 stop4h 09m

$292
Quickest round-trip

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Fri 12/11

6:00 am-10:30 am

1 stop4h 30m

Knoxville McGhee Tyson

Mon 12/14

5:19 pm-9:40 pm

1 stop4h 21m

$301

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Thu 10/29

1:11 pm-8:18 pm

1 stop7h 07m

Knoxville McGhee Tyson

Sun 11/1

6:10 pm-11:59 pm

1 stop5h 49m

$327

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Fri 12/11

6:00 am-3:00 pm

2 stops9h 00m

Knoxville McGhee Tyson

Mon 12/14

7:55 am-12:05 pm

1 stop4h 10m

$359

BuffaloKnoxville

BUF Buffalo - TYS Knoxville McGhee Tyson

BUFTYS

Buffalo

Wed 10/21

8:00 am-4:40 pm

2 stops8h 40m

Knoxville McGhee Tyson

Wed 10/28

7:15 am-3:20 pm

2 stops8h 05m

$370

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Buffalo to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and Knoxville?

Prices are currently low for flights on this route.

Typical prices usually range from $330 to $467.
The lowest price recently found on this route was $287.

What is the cheapest month to fly to Knoxville?

The month of June is, on average, the cheapest month to fly to Knoxville from Buffalo, with most prices found around $344. If you aren’t able to travel during the month of June, then book flights to Knoxville from Buffalo during November instead. Flights to Knoxville in November, while not as cheap as those in June, still average around $346.

When to book flights from Buffalo to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Knoxville (BUF to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Knoxville

Best Price Found

$144

Fastest flight time

3h 39m

Direct flights

None
The best one-way flight to Knoxville from Buffalo in the past 72 hours is $144. The best round-trip flight deal from Buffalo to Knoxville found on momondo in the last 72 hours is $287.
The fastest flight from Buffalo to Knoxville takes 3h 39m
There are no direct flights from Buffalo to Knoxville. There are no popular flight routes from Buffalo to Knoxville.
Search flight deals

Frequently asked questions about flying from Buffalo to Knoxville

  • How far is Buffalo to Knoxville McGhee Tyson by plane?

    The distance between Buffalo and Knoxville McGhee Tyson is about 548.4 mi. By plane, this route typically takes 3h 39m.

  • When did momondo last update prices for flights from Buffalo Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Buffalo Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Buffalo Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Buffalo Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Knoxville?

Best airlines flying from Buffalo to Knoxville

Compare and see reviews for airlines that fly from Buffalo to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $250Free CancellationRating
7.8
8,591 reviews
Search Delta flights
American AirlinesPriceFrom $259Free CancellationRating
7.0
12,076 reviews
Search American Airlines flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
10,226 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Alcoa
Corbin
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Rockford
Jefferson City

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Buffalo to Knoxville for you.

Can I find flights from Buffalo to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Buffalo to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Buffalo to Knoxville?

momondo helps you find the best flight between Buffalo and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Buffalo to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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