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Cheap flights from Brussels Bruxelles-National Airport to South Carolina from $418

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Brussels Bruxelles-National Airport to South Carolina departing on 6/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Brussels Bruxelles-National Airport to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:55 am - 1:00 pm
BRU
-
CLT
32h 05m
1 stop
American Airlines Logo
8:05 pm - 3:15 pm
CLT
-
BRU
13h 10m
1 stop
$687American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
11:00 am - 1:00 pm
BRU
-
CLT
32h 00m
1 stop
American Airlines Logo
8:05 pm - 3:05 pm
CLT
-
BRU
13h 00m
1 stop
$688American Airlines
Wed, Apr 22 - Wed, Apr 29
Multiple Airlines Logo
11:20 am - 8:36 am
BRU
-
CLT
27h 16m
2 stops
Multiple Airlines Logo
5:55 pm - 3:15 pm
CLT
-
BRU
15h 20m
1 stop
$689Multiple Airlines
Tue, Apr 21 - Tue, Apr 28
British Airways Logo
9:15 pm - 3:55 pm
BRU
-
CLT
24h 40m
1 stop
British Airways Logo
6:05 pm - 3:15 pm
CLT
-
BRU
15h 10m
2 stops
$690British Airways
Wed, Jun 10 - Tue, Jun 16
British Airways Logo
10:55 am - 9:05 pm
BRU
-
CLT
16h 10m
2 stops
British Airways Logo
4:44 pm - 3:15 pm
CLT
-
BRU
16h 31m
2 stops
$696British Airways
Tue, Apr 21 - Tue, Apr 28
Lufthansa Logo
8:40 am - 4:45 pm
BRU
-
CLT
14h 05m
1 stop
Lufthansa Logo
10:10 am - 7:15 am
CLT
-
BRU
15h 05m
1 stop
$699Lufthansa
Mon, May 4 - Sun, May 17
Air Canada Logo
2:25 pm - 2:57 pm
BRU
-
CLT
30h 32m
2 stops
Air Canada Logo
6:00 am - 7:10 am
CLT
-
BRU
19h 10m
2 stops
$702Air Canada
Mon, May 4 - Sun, May 17
Multiple Airlines Logo
9:15 pm - 10:40 pm
BRU
-
GSP
31h 25m
2 stops
Multiple Airlines Logo
12:14 pm - 8:25 pm
GSP
-
BRU
26h 11m
2 stops
$763Multiple Airlines
Wed, Apr 22 - Wed, Apr 29
Lufthansa Logo
12:00 pm - 7:09 pm
BRU
-
CAE
13h 09m
1 stop
Lufthansa Logo
10:45 am - 9:00 am
CAE
-
BRU
16h 15m
1 stop
$776Lufthansa
Mon, Jun 29 - Fri, Jul 10
Air Canada Logo
9:55 am - 10:37 am
BRU
-
GSP
54h 42m
2 stops
Air Canada Logo
6:30 am - 7:50 am
GSP
-
BRU
19h 20m
2 stops
$806Air Canada
Sun, Jul 12 - Thu, Aug 6

American Airlines flights from Brussels Bruxelles-National Airport to South Carolina

Our best American Airlines deals on Brussels Bruxelles-National Airport to South Carolina flight tickets
American Airlines
Apr 21
BRU10:55 amBrussels Bruxelles-National
32h 05m
1 stop
CLT1:00 pmCharlotte Douglas
Apr 28
CLT8:05 pmCharlotte Douglas
13h 10m
1 stop
BRU3:15 pmBrussels Bruxelles-National
$687
American Airlines
Apr 22
BRU11:00 amBrussels Bruxelles-National
32h 00m
1 stop
CLT1:00 pmCharlotte Douglas
Apr 29
CLT8:05 pmCharlotte Douglas
13h 00m
1 stop
BRU3:05 pmBrussels Bruxelles-National
$688
American Airlines
May 20
BRU11:00 amBrussels Bruxelles-National
15h 45m
1 stop
CLT8:45 pmCharlotte Douglas
Jun 3
CLT5:47 pmCharlotte Douglas
15h 18m
2 stops
BRU3:05 pmBrussels Bruxelles-National
$692

British Airways flights from Brussels Bruxelles-National Airport to South Carolina

Our best British Airways deals on Brussels Bruxelles-National Airport to South Carolina flight tickets
British Airways
Jun 10
BRU9:15 pmBrussels Bruxelles-National
24h 40m
1 stop
CLT3:55 pmCharlotte Douglas
Jun 16
CLT6:05 pmCharlotte Douglas
15h 10m
2 stops
BRU3:15 pmBrussels Bruxelles-National
$690
British Airways
Apr 21
BRU10:55 amBrussels Bruxelles-National
16h 10m
2 stops
CLT9:05 pmCharlotte Douglas
Apr 28
CLT4:44 pmCharlotte Douglas
16h 31m
2 stops
BRU3:15 pmBrussels Bruxelles-National
$696
British Airways
Apr 22
BRU11:00 amBrussels Bruxelles-National
16h 48m
2 stops
CLT9:48 pmCharlotte Douglas
Apr 29
CLT7:01 pmCharlotte Douglas
14h 04m
2 stops
BRU3:05 pmBrussels Bruxelles-National
$697

momondo Fare Finder

 
Customize your flight search to find flights from Brussels Bruxelles-National Airport to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Tue 4/21

10:55 am-1:00 pm

1 stop32h 05m

Charlotte Douglas

Tue 4/28

8:05 pm-3:15 pm

1 stop13h 10m

$687

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Wed 4/22

11:00 am-1:00 pm

1 stop32h 00m

Charlotte Douglas

Wed 4/29

8:05 pm-3:05 pm

1 stop13h 00m

$688

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Tue 4/21

11:20 am-8:36 am

2 stops27h 16m

Charlotte Douglas

Tue 4/28

5:55 pm-3:15 pm

1 stop15h 20m

$689

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Wed 6/10

9:15 pm-3:55 pm

1 stop24h 40m

Charlotte Douglas

Tue 6/16

6:05 pm-3:15 pm

2 stops15h 10m

$690

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Tue 4/21

10:55 am-9:05 pm

2 stops16h 10m

Charlotte Douglas

Tue 4/28

4:44 pm-3:15 pm

2 stops16h 31m

$696
Quickest round-trip

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Mon 5/4

8:40 am-4:45 pm

1 stop14h 05m

Charlotte Douglas

Sun 5/17

10:10 am-7:15 am

1 stop15h 05m

$699

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Mon 5/4

2:25 pm-2:57 pm

2 stops30h 32m

Charlotte Douglas

Sun 5/17

6:00 am-7:10 am

2 stops19h 10m

$702

BrusselsGreenville

BRU - GSP

BRUGSP

Brussels Bruxelles-National

Wed 4/22

9:15 pm-10:40 pm

2 stops31h 25m

Greenville

Wed 4/29

12:14 pm-8:25 pm

2 stops26h 11m

$763

BrusselsColumbia

BRU - CAE

BRUCAE

Brussels Bruxelles-National

Mon 6/29

12:00 pm-7:09 pm

1 stop13h 09m

Columbia Metropolitan

Fri 7/10

10:45 am-9:00 am

1 stop16h 15m

$776

BrusselsGreenville

BRU - GSP

BRUGSP

Brussels Bruxelles-National

Sun 7/12

9:55 am-10:37 am

2 stops54h 42m

Greenville

Thu 8/6

6:30 am-7:50 am

2 stops19h 20m

$806

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Brussels Bruxelles-National Airport to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Brussels Bruxelles-National Airport to South Carolina flights?

You could potentially save up to 37% on your flight if you consider stops on a Brussels Bruxelles-National Airport to South Carolina flight.

Cheap Brussels Bruxelles-National Airport to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Brussels Bruxelles-National Airport to South Carolina

Fastest flight time

12h 45m

Direct flights

None
The fastest flight from Brussels Bruxelles-National Airport to South Carolina takes 12h 45m
There are no direct flights from Brussels Bruxelles-National Airport to South Carolina. There are no popular flight routes from Brussels Bruxelles-National Airport to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Brussels Bruxelles-National Airport to South Carolina?

    Prices for flights from Brussels Bruxelles-National Airport to South Carolina are updated daily.

  • How many operators does momondo search for flights from Brussels Bruxelles-National Airport to South Carolina?

  • How old do you have to be to fly from Brussels Bruxelles-National Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Brussels Bruxelles-National Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Brussels to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Brussels to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Brussels to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Brussels to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Brussels to South Carolina?

Once you have performed a search for Brussels to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Brussels to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Brussels to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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