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Cheap flights from Brussels Bruxelles-National Airport to South Carolina from $369

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Brussels Bruxelles-National Airport to South Carolina departing on 5/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Brussels Bruxelles-National Airport to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:30 am - 7:02 pm
BRU
-
CLT
14h 32m
2 stops
Multiple Airlines Logo
7:44 pm - 7:10 am
CLT
-
BRU
29h 26m
2 stops
$772Multiple Airlines
Sat, Jun 6 - Sat, Jun 20
Lufthansa Logo
10:30 am - 7:02 pm
BRU
-
CLT
14h 32m
2 stops
Lufthansa Logo
7:44 pm - 7:15 am
CLT
-
BRU
29h 31m
1 stop
$773Lufthansa
Sat, Jun 6 - Sat, Jun 20
Air Canada Logo
2:25 pm - 2:57 pm
BRU
-
CLT
30h 32m
2 stops
Air Canada Logo
3:35 pm - 1:15 pm
CLT
-
BRU
15h 40m
2 stops
$774Air Canada
Mon, May 11 - Tue, May 26
Multiple Airlines Logo
10:30 am - 6:55 pm
BRU
-
CLT
14h 25m
2 stops
Multiple Airlines Logo
2:59 pm - 7:25 am
CLT
-
BRU
10h 26m
1 stop
$776Multiple Airlines
Wed, Aug 26 - Fri, Sep 4
United Airlines Logo
7:00 am - 11:29 pm
BRU
-
GSP
22h 29m
2 stops
United Airlines Logo
6:30 am - 7:45 am
GSP
-
BRU
19h 15m
1 stop
$854United Airlines
Tue, Jun 9 - Tue, Jun 16
United Airlines Logo
7:00 am - 9:17 pm
BRU
-
GSP
20h 17m
2 stops
United Airlines Logo
6:30 am - 7:45 am
GSP
-
BRU
19h 15m
1 stop
$855United Airlines
Sun, May 24 - Sun, May 31
American Airlines Logo
10:45 am - 7:43 pm
BRU
-
CHS
14h 58m
2 stops
American Airlines Logo
3:15 pm - 3:15 pm
CHS
-
BRU
18h 00m
2 stops
$862American Airlines
Fri, Sep 25 - Tue, Sep 29
American Airlines Logo
10:45 am - 7:43 pm
BRU
-
CHS
14h 58m
2 stops
American Airlines Logo
3:15 pm - 3:15 pm
CHS
-
BRU
18h 00m
2 stops
$864American Airlines
Fri, Sep 25 - Tue, Sep 29
Delta Logo
9:45 am - 7:02 pm
BRU
-
CHS
15h 17m
1 stop
Delta Logo
6:00 am - 7:35 am
CHS
-
BRU
19h 35m
2 stops
$865Delta
Fri, May 22 - Sat, May 30
Delta Logo
10:25 am - 11:59 pm
BRU
-
CHS
19h 34m
2 stops
Delta Logo
6:00 am - 7:35 am
CHS
-
BRU
19h 35m
2 stops
$867Delta
Fri, May 22 - Sat, May 30

Lufthansa flights from Brussels Bruxelles-National Airport to South Carolina

Our best Lufthansa deals on Brussels Bruxelles-National Airport to South Carolina flight tickets
Lufthansa
Jun 6
BRU10:30 amBrussels Bruxelles-National
14h 32m
2 stops
CLT7:02 pmCharlotte Douglas
Jun 20
CLT7:44 pmCharlotte Douglas
29h 31m
1 stop
BRU7:15 amBrussels Bruxelles-National
$773
Lufthansa
Aug 26
BRU9:35 amBrussels Bruxelles-National
13h 10m
1 stop
CLT4:45 pmCharlotte Douglas
Sep 4
CLT2:59 pmCharlotte Douglas
10h 16m
1 stop
BRU7:15 amBrussels Bruxelles-National
$783
Lufthansa
May 11
BRU10:15 amBrussels Bruxelles-National
12h 56m
1 stop
CLT5:11 pmCharlotte Douglas
May 26
CLT10:27 amCharlotte Douglas
14h 48m
1 stop
BRU7:15 amBrussels Bruxelles-National
$785

KLM flights from Brussels Bruxelles-National Airport to South Carolina

Our best KLM deals on Brussels Bruxelles-National Airport to South Carolina flight tickets
KLM
May 10
BRU8:05 amBrussels Bruxelles-National
16h 15m
2 stops
CLT6:20 pmCharlotte Douglas
May 26
CLT5:30 pmCharlotte Douglas
32h 10m
1 stop
BRU7:40 amBrussels Bruxelles-National
$804
KLM
May 8
BRU3:10 pmBrussels Bruxelles-National
14h 34m
2 stops
CAE11:44 pmColumbia Metropolitan
May 17
CAE7:17 pmColumbia Metropolitan
30h 23m
1 stop
BRU7:40 amBrussels Bruxelles-National
$927
KLM
May 8
BRU6:20 amBrussels Bruxelles-National
15h 49m
2 stops
CLT4:09 pmCharlotte Douglas
May 18
CLT2:14 pmCharlotte Douglas
13h 26m
2 stops
BRU9:40 amBrussels Bruxelles-National
$938

momondo Fare Finder

 
Customize your flight search to find flights from Brussels Bruxelles-National Airport to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Sat 6/6

10:30 am-7:02 pm

2 stops14h 32m

Charlotte Douglas

Sat 6/20

7:44 pm-7:10 am

2 stops29h 26m

$772

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Sat 6/6

10:30 am-7:02 pm

2 stops14h 32m

Charlotte Douglas

Sat 6/20

7:44 pm-7:15 am

1 stop29h 31m

$773

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Mon 5/11

2:25 pm-2:57 pm

2 stops30h 32m

Charlotte Douglas

Tue 5/26

3:35 pm-1:15 pm

2 stops15h 40m

$774
Quickest round-trip

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Wed 8/26

10:30 am-6:55 pm

2 stops14h 25m

Charlotte Douglas

Fri 9/4

2:59 pm-7:25 am

1 stop10h 26m

$776

BrusselsGreenville

BRU - GSP

BRUGSP

Brussels Bruxelles-National

Tue 6/9

7:00 am-11:29 pm

2 stops22h 29m

Greenville

Tue 6/16

6:30 am-7:45 am

1 stop19h 15m

$854

BrusselsGreenville

BRU - GSP

BRUGSP

Brussels Bruxelles-National

Sun 5/24

7:00 am-9:17 pm

2 stops20h 17m

Greenville

Sun 5/31

6:30 am-7:45 am

1 stop19h 15m

$855

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Fri 9/25

10:45 am-7:43 pm

2 stops14h 58m

Charleston

Tue 9/29

3:15 pm-3:15 pm

2 stops18h 00m

$862

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Fri 9/25

10:45 am-7:43 pm

2 stops14h 58m

Charleston

Tue 9/29

3:15 pm-3:15 pm

2 stops18h 00m

$864

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Fri 5/22

9:45 am-7:02 pm

1 stop15h 17m

Charleston

Sat 5/30

6:00 am-7:35 am

2 stops19h 35m

$865

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Fri 5/22

10:25 am-11:59 pm

2 stops19h 34m

Charleston

Sat 5/30

6:00 am-7:35 am

2 stops19h 35m

$867

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Brussels Bruxelles-National Airport to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Brussels Bruxelles-National Airport to South Carolina flights?

You could potentially save up to 39% on your flight if you consider stops on a Brussels Bruxelles-National Airport to South Carolina flight.

Cheap Brussels Bruxelles-National Airport to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Brussels Bruxelles-National Airport to South Carolina

Fastest flight time

13h 03m

Direct flights

None
The fastest flight from Brussels Bruxelles-National Airport to South Carolina takes 13h 03m
There are no direct flights from Brussels Bruxelles-National Airport to South Carolina. There are no popular flight routes from Brussels Bruxelles-National Airport to South Carolina.
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Frequently asked questions about flying from Brussels Bruxelles-National Airport to South Carolina

  • When did momondo last update prices for flights from Brussels Bruxelles-National Airport to South Carolina?

    Prices for flights from Brussels Bruxelles-National Airport to South Carolina are updated daily.

  • How many operators does momondo search for flights from Brussels Bruxelles-National Airport to South Carolina?

  • How old do you have to be to fly from Brussels Bruxelles-National Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Brussels Bruxelles-National Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Brussels to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Brussels to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Brussels to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Brussels to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Brussels to South Carolina?

Once you have performed a search for Brussels to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Brussels to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Brussels to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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