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Cheap flights from Brussels Bruxelles-National Airport to South Carolina from $420

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Brussels Bruxelles-National Airport to South Carolina departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Brussels Bruxelles-National Airport to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:35 pm - 1:55 pm
BRU
-
CLT
22h 20m1 stop
Multiple Airlines Logo
6:25 pm - 7:30 pm
CLT
-
BRU
19h 05m1 stop
$570Multiple Airlines
Sun, Feb 15 - Thu, Feb 26
Multiple Airlines Logo
11:50 am - 7:05 pm
BRU
-
CLT
13h 15m1 stop
Multiple Airlines Logo
3:15 pm - 10:50 am
CLT
-
BRU
14h 35m2 stops
$585Multiple Airlines
Mon, Mar 2 - Sun, Mar 22
British Airways Logo
10:25 am - 9:15 pm
BRU
-
CLT
16h 50m2 stops
British Airways Logo
6:25 pm - 4:20 pm
CLT
-
BRU
15h 55m1 stop
$586British Airways
Wed, Feb 18 - Wed, Feb 25
British Airways Logo
11:50 am - 7:05 pm
BRU
-
CLT
13h 15m1 stop
British Airways Logo
8:20 pm - 4:35 pm
CLT
-
BRU
14h 15m1 stop
$598British Airways
Wed, Feb 11 - Sat, Feb 21
American Airlines Logo
11:45 am - 4:05 pm
BRU
-
CLT
34h 20m1 stop
American Airlines Logo
11:15 pm - 10:30 am
CLT
-
BRU
29h 15m1 stop
$603American Airlines
Fri, Jan 16 - Fri, Jan 30
American Airlines Logo
3:00 pm - 2:15 pm
BRU
-
CLT
29h 15m1 stop
American Airlines Logo
3:15 pm - 10:50 am
CLT
-
BRU
13h 35m2 stops
$604American Airlines
Sun, Feb 8 - Fri, Feb 20
KLM Logo
8:05 am - 6:02 pm
BRU
-
CLT
15h 57m2 stops
KLM Logo
2:10 pm - 10:10 am
CLT
-
BRU
14h 00m2 stops
$606KLM
Fri, Feb 20 - Fri, Feb 27
KLM Logo
6:15 am - 5:13 pm
BRU
-
CHS
16h 58m2 stops
KLM Logo
11:29 am - 7:35 am
CHS
-
BRU
14h 06m2 stops
$645KLM
Fri, Jan 23 - Thu, Feb 12
Lufthansa Logo
10:30 am - 8:02 pm
BRU
-
CHS
15h 32m2 stops
Lufthansa Logo
2:48 pm - 7:15 am
CHS
-
BRU
10h 27m1 stop
$692Lufthansa
Fri, Jan 23 - Thu, Feb 12
Lufthansa Logo
11:55 am - 7:04 pm
BRU
-
CHS
13h 09m1 stop
Lufthansa Logo
11:15 am - 8:05 am
CHS
-
BRU
14h 50m1 stop
$694Lufthansa
Fri, Jan 23 - Thu, Feb 12

American Airlines flights from Brussels Bruxelles-National Airport to South Carolina

Our best American Airlines deals on Brussels Bruxelles-National Airport to South Carolina flight tickets
American Airlines
Jan 16
BRU11:45 amBrussels Bruxelles-National
34h 20m
1 stop
CLT4:05 pmCharlotte Douglas
Jan 30
CLT11:15 pmCharlotte Douglas
29h 15m
1 stop
BRU10:30 amBrussels Bruxelles-National
$603
Find similar
American Airlines
Feb 8
BRU3:00 pmBrussels Bruxelles-National
29h 15m
1 stop
CLT2:15 pmCharlotte Douglas
Feb 20
CLT3:15 pmCharlotte Douglas
13h 35m
2 stops
BRU10:50 amBrussels Bruxelles-National
$604
Find similar
American Airlines
Jan 16
BRU11:45 amBrussels Bruxelles-National
17h 09m
2 stops
CLT10:54 pmCharlotte Douglas
Jan 30
CLT1:45 pmCharlotte Douglas
15h 05m
2 stops
BRU10:50 amBrussels Bruxelles-National
$609
Find similar

United Airlines flights from Brussels Bruxelles-National Airport to South Carolina

Our best United Airlines deals on Brussels Bruxelles-National Airport to South Carolina flight tickets
United Airlines
Feb 3
BRU9:00 amBrussels Bruxelles-National
18h 16m
2 stops
CLT9:16 pmCharlotte Douglas
Feb 10
CLT2:20 pmCharlotte Douglas
11h 45m
1 stop
BRU8:05 amBrussels Bruxelles-National
$690
Find similar
United Airlines
Feb 1
BRU9:30 amBrussels Bruxelles-National
17h 46m
2 stops
CLT9:16 pmCharlotte Douglas
Feb 8
CLT1:50 pmCharlotte Douglas
17h 25m
2 stops
BRU1:15 pmBrussels Bruxelles-National
$691
Find similar
United Airlines
Feb 1
BRU9:30 amBrussels Bruxelles-National
17h 46m
2 stops
CLT9:16 pmCharlotte Douglas
Feb 8
CLT9:55 amCharlotte Douglas
15h 20m
1 stop
BRU7:15 amBrussels Bruxelles-National
$692
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Brussels Bruxelles-National Airport to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Sun 2/15

9:35 pm-1:55 pm

1 stop22h 20m

Charlotte Douglas

Thu 2/26

6:25 pm-7:30 pm

1 stop19h 05m

$570

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Mon 3/2

11:50 am-7:05 pm

1 stop13h 15m

Charlotte Douglas

Sun 3/22

3:15 pm-10:50 am

2 stops14h 35m

$585

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Wed 2/18

10:25 am-9:15 pm

2 stops16h 50m

Charlotte Douglas

Wed 2/25

6:25 pm-4:20 pm

1 stop15h 55m

$586

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Wed 2/11

11:50 am-7:05 pm

1 stop13h 15m

Charlotte Douglas

Sat 2/21

8:20 pm-4:35 pm

1 stop14h 15m

$598

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Fri 1/16

11:45 am-4:05 pm

1 stop34h 20m

Charlotte Douglas

Fri 1/30

11:15 pm-10:30 am

1 stop29h 15m

$603

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Sun 2/8

3:00 pm-2:15 pm

1 stop29h 15m

Charlotte Douglas

Fri 2/20

3:15 pm-10:50 am

2 stops13h 35m

$604

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Fri 2/20

8:05 am-6:02 pm

2 stops15h 57m

Charlotte Douglas

Fri 2/27

2:10 pm-10:10 am

2 stops14h 00m

$606

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Fri 1/23

6:15 am-5:13 pm

2 stops16h 58m

Charleston

Thu 2/12

11:29 am-7:35 am

2 stops14h 06m

$645

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Fri 1/23

10:30 am-8:02 pm

2 stops15h 32m

Charleston

Thu 2/12

2:48 pm-7:15 am

1 stop10h 27m

$692

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Fri 1/23

11:55 am-7:04 pm

1 stop13h 09m

Charleston

Thu 2/12

11:15 am-8:05 am

1 stop14h 50m

$694

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Brussels Bruxelles-National Airport to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Brussels Bruxelles-National Airport to South Carolina flights?

You could potentially save up to 42% on your flight if you consider stops on a Brussels Bruxelles-National Airport to South Carolina flight.

Cheap Brussels Bruxelles-National Airport to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Brussels Bruxelles-National Airport to South Carolina

Fastest flight time

13h 15m

Direct flights

None
The fastest flight from Brussels Bruxelles-National Airport to South Carolina takes 13h 15m
There are no direct flights from Brussels Bruxelles-National Airport to South Carolina. There are no popular flight routes from Brussels Bruxelles-National Airport to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Brussels Bruxelles-National Airport to South Carolina?

    Prices for flights from Brussels Bruxelles-National Airport to South Carolina are updated daily.

  • How many operators does momondo search for flights from Brussels Bruxelles-National Airport to South Carolina?

  • How old do you have to be to fly from Brussels Bruxelles-National Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Brussels Bruxelles-National Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Brussels to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Brussels to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Brussels to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Brussels to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Brussels to South Carolina?

Once you have performed a search for Brussels to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Brussels to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Brussels to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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