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Cheap flights from Brussels Bruxelles-National Airport to South Carolina from $425

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Brussels Bruxelles-National Airport to South Carolina departing on 9/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Brussels Bruxelles-National Airport to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
9:35 am - 4:45 pm
BRU
-
CLT
13h 10m
1 stop
Lufthansa Logo
6:40 pm - 4:15 pm
CLT
-
BRU
15h 35m
1 stop
$754Lufthansa
Tue, Aug 18 - Tue, Aug 25
Multiple Airlines Logo
9:55 am - 8:59 pm
BRU
-
CLT
17h 04m
2 stops
Multiple Airlines Logo
3:00 pm - 7:15 am
CLT
-
BRU
10h 15m
1 stop
$756Multiple Airlines
Fri, Aug 21 - Thu, Sep 3
Lufthansa Logo
6:45 am - 4:45 pm
BRU
-
CLT
16h 00m
1 stop
Lufthansa Logo
3:00 pm - 7:15 am
CLT
-
BRU
10h 15m
1 stop
$758Lufthansa
Fri, Aug 21 - Thu, Sep 3
Multiple Airlines Logo
2:25 pm - 2:59 pm
BRU
-
CLT
30h 34m
2 stops
Multiple Airlines Logo
3:00 pm - 7:15 am
CLT
-
BRU
10h 15m
1 stop
$759Multiple Airlines
Tue, Aug 18 - Tue, Aug 25
Air Canada Logo
6:20 am - 8:59 pm
BRU
-
CLT
20h 39m
2 stops
Air Canada Logo
3:40 pm - 1:15 pm
CLT
-
BRU
15h 35m
2 stops
$763Air Canada
Fri, Aug 21 - Thu, Sep 3
United Airlines Logo
8:30 am - 11:52 pm
BRU
-
CHS
21h 22m
2 stops
United Airlines Logo
3:17 pm - 1:15 pm
CHS
-
BRU
15h 58m
2 stops
$834United Airlines
Sun, Jul 19 - Sat, Jul 25
United Airlines Logo
8:30 am - 11:52 pm
BRU
-
CHS
21h 22m
2 stops
United Airlines Logo
10:00 am - 7:25 am
CHS
-
BRU
15h 25m
1 stop
$835United Airlines
Sun, Jul 19 - Sat, Jul 25
American Airlines Logo
7:00 am - 12:03 am
BRU
-
FLO
23h 03m
2 stops
American Airlines Logo
6:31 pm - 5:00 pm
FLO
-
BRU
40h 29m
2 stops
$860American Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
7:00 am - 12:03 am
BRU
-
FLO
23h 03m
2 stops
American Airlines Logo
6:31 pm - 5:00 pm
FLO
-
BRU
40h 29m
2 stops
$861American Airlines
Thu, Dec 3 - Mon, Dec 7
Brussels Airlines Logo
6:05 pm - 7:07 pm
BRU
-
CAE
31h 02m
2 stops
Brussels Airlines Logo
2:56 pm - 10:55 am
CAE
-
BRU
13h 59m
2 stops
$937Brussels Airlines
Sun, Aug 16 - Sun, Aug 23

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Delta flights from Brussels Bruxelles-National Airport to South Carolina

Our best Delta deals on Brussels Bruxelles-National Airport to South Carolina flight tickets
Delta
Aug 26
BRU6:20 amBrussels Bruxelles-National
18h 22m
2 stops
CLT6:42 pmCharlotte Douglas
Sep 4
CLT4:58 pmCharlotte Douglas
15h 42m
2 stops
BRU2:40 pmBrussels Bruxelles-National
$811
Delta
Jul 21
BRU10:25 amBrussels Bruxelles-National
17h 42m
2 stops
CHS10:07 pmCharleston
Jul 25
CHS5:35 pmCharleston
34h 05m
2 stops
BRU9:40 amBrussels Bruxelles-National
$1,039
Delta
Jul 18
BRU3:10 pmBrussels Bruxelles-National
14h 44m
2 stops
GSP11:54 pmGreenville
Jul 22
GSP6:52 pmGreenville
30h 43m
2 stops
BRU7:35 amBrussels Bruxelles-National
$1,248

Lufthansa flights from Brussels Bruxelles-National Airport to South Carolina

Our best Lufthansa deals on Brussels Bruxelles-National Airport to South Carolina flight tickets
Lufthansa
Aug 18
BRU9:35 amBrussels Bruxelles-National
13h 10m
1 stop
CLT4:45 pmCharlotte Douglas
Aug 25
CLT6:40 pmCharlotte Douglas
15h 35m
1 stop
BRU4:15 pmBrussels Bruxelles-National
$754
Lufthansa
Aug 21
BRU6:45 amBrussels Bruxelles-National
16h 00m
1 stop
CLT4:45 pmCharlotte Douglas
Sep 3
CLT3:00 pmCharlotte Douglas
10h 15m
1 stop
BRU7:15 amBrussels Bruxelles-National
$758
Lufthansa
Aug 21
BRU6:45 amBrussels Bruxelles-National
16h 00m
1 stop
CLT4:45 pmCharlotte Douglas
Sep 3
CLT3:00 pmCharlotte Douglas
10h 15m
1 stop
BRU7:15 amBrussels Bruxelles-National
$760

momondo Fare Finder

 
Customize your flight search to find flights from Brussels Bruxelles-National Airport to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 5, 2026.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Tue 8/18

9:35 am-4:45 pm

1 stop13h 10m

Charlotte Douglas

Tue 8/25

6:40 pm-4:15 pm

1 stop15h 35m

$754

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Fri 8/21

9:55 am-8:59 pm

2 stops17h 04m

Charlotte Douglas

Thu 9/3

3:00 pm-7:15 am

1 stop10h 15m

$756
Quickest round-trip

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Fri 8/21

6:45 am-4:45 pm

1 stop16h 00m

Charlotte Douglas

Thu 9/3

3:00 pm-7:15 am

1 stop10h 15m

$758

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Tue 8/18

2:25 pm-2:59 pm

2 stops30h 34m

Charlotte Douglas

Tue 8/25

3:00 pm-7:15 am

1 stop10h 15m

$759

BrusselsCharlotte

BRU - CLT

BRUCLT

Brussels Bruxelles-National

Fri 8/21

6:20 am-8:59 pm

2 stops20h 39m

Charlotte Douglas

Thu 9/3

3:40 pm-1:15 pm

2 stops15h 35m

$763

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Sun 7/19

8:30 am-11:52 pm

2 stops21h 22m

Charleston

Sat 7/25

3:17 pm-1:15 pm

2 stops15h 58m

$834

BrusselsCharleston

BRU - CHS

BRUCHS

Brussels Bruxelles-National

Sun 7/19

8:30 am-11:52 pm

2 stops21h 22m

Charleston

Sat 7/25

10:00 am-7:25 am

1 stop15h 25m

$835

BrusselsFlorence

BRU - FLO

BRUFLO

Brussels Bruxelles-National

Thu 12/3

7:00 am-12:03 am

2 stops23h 03m

Florence

Mon 12/7

6:31 pm-5:00 pm

2 stops40h 29m

$860

BrusselsFlorence

BRU - FLO

BRUFLO

Brussels Bruxelles-National

Thu 12/3

7:00 am-12:03 am

2 stops23h 03m

Florence

Mon 12/7

6:31 pm-5:00 pm

2 stops40h 29m

$861

BrusselsColumbia

BRU - CAE

BRUCAE

Brussels Bruxelles-National

Sun 8/16

6:05 pm-7:07 pm

2 stops31h 02m

Columbia Metropolitan

Sun 8/23

2:56 pm-10:55 am

2 stops13h 59m

$937

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Brussels Bruxelles-National Airport to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Brussels Bruxelles-National Airport to South Carolina flights?

You could potentially save up to 39% on your flight if you consider stops on a Brussels Bruxelles-National Airport to South Carolina flight.

Cheap Brussels Bruxelles-National Airport to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Brussels Bruxelles-National Airport to South Carolina

Fastest flight time

13h 07m

Direct flights

None
The fastest flight from Brussels Bruxelles-National Airport to South Carolina takes 13h 07m
There are no direct flights from Brussels Bruxelles-National Airport to South Carolina. There are no popular flight routes from Brussels Bruxelles-National Airport to South Carolina.
Search flight deals

Frequently asked questions about flying from Brussels Bruxelles-National Airport to South Carolina

  • When did momondo last update prices for flights from Brussels Bruxelles-National Airport to South Carolina?

    Prices for flights from Brussels Bruxelles-National Airport to South Carolina are updated daily.

  • How many operators does momondo search for flights from Brussels Bruxelles-National Airport to South Carolina?

  • How old do you have to be to fly from Brussels Bruxelles-National Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Brussels Bruxelles-National Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Brussels Bruxelles-National Airport to South Carolina

Compare and see reviews for airlines that fly from Brussels Bruxelles-National Airport to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $715Free CancellationRating
7.4
9,933 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Brussels to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Brussels to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Brussels to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Brussels to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Brussels to South Carolina?

Once you have performed a search for Brussels to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Brussels to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Brussels to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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