Cheap flights from Arizona to Knoxville from $80

The month of February is, on average, the cheapest month to fly to Knoxville from Arizona, with most prices found around $255. If you aren’t able to travel during the month of February, then book flights to Knoxville from Arizona during January instead. Flights to Knoxville in January, while not as cheap as those in February, still average around $263.

The cheapest day to depart from Arizona to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $124. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Arizona to Knoxville for around $310.

In the morning is the cheapest time of day to fly from Arizona to Knoxville when you can find flight prices for as low as $207. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $259.

Fly from Phoenix Sky Harbor Intl to Knoxville McGhee Tyson for the best Arizona - Knoxville McGhee Tyson flight prices

You are more likely to see cheaper flights to Knoxville from Arizona when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $298 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Arizona for as low as $209 on momondo.

There is only 1 cabin class available to choose from on Arizona to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, United Airlines, and American Airlines are the most popular carriers operating from Arizona to Knoxville McGhee Tyson

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Knoxville from Arizona according to our data. American Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

4 flights are operational weekly from Arizona to Knoxville as of April 2026. The most popular departure day for this route is Thu, with 50% of flights per week taking off on this day.

Average flight duration from Arizona to Knoxville depends on which airport you fly into and out of. Flying from Phoenix to Knoxville is 3h 24m on average, while flying from Tucson to Knoxville is 5h 53m on average. Knoxville is the most popular airport in Knoxville.