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Cheap flights from Tampa to Mayagüez from $374

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Mayagüez departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Tampa to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:00 am - 12:44 pm
TPA
-
MAZ
5h 44m
1 stop
Multiple Airlines Logo
4:36 pm - 11:57 pm
MAZ
-
TPA
7h 21m
1 stop
$374Multiple Airlines
Tue, Apr 7 - Fri, Apr 10
Multiple Airlines Logo
8:14 am - 9:42 am
TPA
-
MAZ
25h 28m
2 stops
Multiple Airlines Logo
4:36 pm - 11:57 pm
MAZ
-
TPA
7h 21m
1 stop
$386Multiple Airlines
Tue, Apr 7 - Fri, Apr 10
Multiple Airlines Logo
8:10 am - 12:44 pm
TPA
-
MAZ
28h 34m
1 stop
Multiple Airlines Logo
4:36 pm - 9:00 am
MAZ
-
TPA
16h 24m
1 stop
$432Multiple Airlines
Wed, Mar 11 - Sun, Mar 15
Multiple Airlines Logo
8:10 am - 12:44 pm
TPA
-
MAZ
28h 34m
1 stop
Multiple Airlines Logo
4:36 pm - 7:19 am
MAZ
-
TPA
14h 43m
2 stops
$446Multiple Airlines
Wed, Mar 11 - Sun, Mar 15
Multiple Airlines Logo
10:54 pm - 6:43 pm
TPA
-
MAZ
19h 49m
2 stops
Multiple Airlines Logo
7:35 am - 3:33 pm
MAZ
-
TPA
7h 58m
1 stop
$474Multiple Airlines
Fri, Mar 13 - Tue, Mar 17
Multiple Airlines Logo
9:55 am - 12:44 pm
TPA
-
MAZ
26h 49m
1 stop
Multiple Airlines Logo
1:19 pm - 7:19 am
MAZ
-
TPA
18h 00m
2 stops
$497Multiple Airlines
Sun, Mar 15 - Thu, Mar 19
Multiple Airlines Logo
4:23 pm - 12:44 pm
TPA
-
MAZ
20h 21m
2 stops
Multiple Airlines Logo
4:36 pm - 7:19 am
MAZ
-
TPA
14h 43m
2 stops
$509Multiple Airlines
Sun, Mar 15 - Thu, Mar 19
Multiple Airlines Logo
6:46 pm - 12:44 pm
TPA
-
MAZ
17h 58m
3 stops
Multiple Airlines Logo
4:36 pm - 7:19 am
MAZ
-
TPA
14h 43m
2 stops
$558Multiple Airlines
Sun, Mar 15 - Thu, Mar 19
Multiple Airlines Logo
9:55 am - 4:11 pm
TPA
-
MAZ
6h 16m
1 stop
Multiple Airlines Logo
1:19 pm - 9:00 am
MAZ
-
TPA
19h 41m
1 stop
$608Multiple Airlines
Sun, Mar 15 - Thu, Mar 19
Multiple Airlines Logo
9:55 am - 9:42 am
TPA
-
MAZ
23h 47m
1 stop
Multiple Airlines Logo
7:35 am - 3:33 pm
MAZ
-
TPA
7h 58m
1 stop
$658Multiple Airlines
Fri, Mar 13 - Tue, Mar 17

United Airlines flights from Tampa to Mayagüez

Our best United Airlines deals on Tampa to Mayagüez flight tickets
United Airlines
Jul 25
TPA6:00 amTampa
9h 49m
2 stops
MAZ3:49 pmMayagüez Eugenio M De Hostos
Aug 1
MAZ1:25 pmMayagüez Eugenio M De Hostos
21h 20m
2 stops
TPA10:45 amTampa
$1,708
United Airlines
Mar 4
TPA6:55 pmTampa
20h 16m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Mar 9
MAZ1:19 pmMayagüez Eugenio M De Hostos
21h 12m
2 stops
TPA10:31 amTampa
$1,858
United Airlines
May 11
TPA6:57 pmTampa
21h 14m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
May 13
MAZ1:19 pmMayagüez Eugenio M De Hostos
26h 09m
2 stops
TPA3:28 pmTampa
$2,010

JetBlue flights from Tampa to Mayagüez

Our best JetBlue deals on Tampa to Mayagüez flight tickets
JetBlue
Jul 25
TPA10:05 amTampa
8h 45m
1 stop
MAZ6:50 pmMayagüez Eugenio M De Hostos
Aug 1
MAZ1:25 pmMayagüez Eugenio M De Hostos
8h 15m
2 stops
TPA9:40 pmTampa
$702
JetBlue
Jul 25
TPA10:05 amTampa
5h 44m
1 stop
MAZ3:49 pmMayagüez Eugenio M De Hostos
Aug 1
MAZ1:25 pmMayagüez Eugenio M De Hostos
11h 34m
1 stop
TPA12:59 amTampa
$733

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from Tampa to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Tue 4/7

7:00 am-12:44 pm

1 stop5h 44m

Mayagüez Eugenio M De Hostos

Fri 4/10

4:36 pm-11:57 pm

1 stop7h 21m

$374

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Tue 4/7

8:14 am-9:42 am

2 stops25h 28m

Mayagüez Eugenio M De Hostos

Fri 4/10

4:36 pm-11:57 pm

1 stop7h 21m

$386

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Wed 3/11

8:10 am-12:44 pm

1 stop28h 34m

Mayagüez Eugenio M De Hostos

Sun 3/15

4:36 pm-9:00 am

1 stop16h 24m

$432

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Wed 3/11

8:10 am-12:44 pm

1 stop28h 34m

Mayagüez Eugenio M De Hostos

Sun 3/15

4:36 pm-7:19 am

2 stops14h 43m

$446

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Fri 3/13

10:54 pm-6:43 pm

2 stops19h 49m

Mayagüez Eugenio M De Hostos

Tue 3/17

7:35 am-3:33 pm

1 stop7h 58m

$474

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 3/15

9:55 am-12:44 pm

1 stop26h 49m

Mayagüez Eugenio M De Hostos

Thu 3/19

1:19 pm-7:19 am

2 stops18h 00m

$497

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 3/15

4:23 pm-12:44 pm

2 stops20h 21m

Mayagüez Eugenio M De Hostos

Thu 3/19

4:36 pm-7:19 am

2 stops14h 43m

$509

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 3/15

6:46 pm-12:44 pm

3 stops17h 58m

Mayagüez Eugenio M De Hostos

Thu 3/19

4:36 pm-7:19 am

2 stops14h 43m

$558

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 3/15

9:55 am-4:11 pm

1 stop6h 16m

Mayagüez Eugenio M De Hostos

Thu 3/19

1:19 pm-9:00 am

1 stop19h 41m

$608

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Fri 3/13

9:55 am-9:42 am

1 stop23h 47m

Mayagüez Eugenio M De Hostos

Tue 3/17

7:35 am-3:33 pm

1 stop7h 58m

$658

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Mayagüez from

How to get the cheapest flight ticket from Tampa to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Mayagüez?

Frontier, JetBlue and Spirit Airlines are the top three most popular airlines that fly to Mayagüez from Tampa according to our data. Frontier is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 7 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

When to book flights from Tampa to Mayagüez

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Mayagüez according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Mayagüez (TPA to MAZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Mayagüez

Fastest flight time

8h 45m

Direct flights

None
The fastest flight from Tampa to Mayagüez takes 8h 45m
There are no direct flights from Tampa to Mayagüez. There are no popular flight routes from Tampa to Mayagüez.
Search flight deals

  • How far is Tampa to Mayagüez Eugenio M De Hostos by plane?

    Mayagüez Eugenio M De Hostos is 1181.4 mi away from Tampa. 8h 45m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport refresh daily.

  • How old do you have to be to fly from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The travel and health documents required for your trip to Mayagüez Eugenio M De Hostos Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mayagüez Eugenio M De Hostos Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Mayagüez?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Mayagüez for you.

Can I find flights from Tampa to Mayagüez with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Tampa to Mayagüez flights to just show those with flexible booking policies.

How can momondo help me find flights from Tampa to Mayagüez?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mayagüez from Tampa.

I’m not ready to book a flight from Tampa to Mayagüez right now. Can momondo alert me if prices change?

Price alerts on flights to Mayagüez from Tampa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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