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Cheap flights from Tampa to Mayagüez from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Mayagüez departing on 2/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Tampa to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:34 pm - 9:42 am
TPA
-
MAZ
10h 08m
1 stop
Multiple Airlines Logo
1:19 pm - 4:46 pm
MAZ
-
TPA
28h 27m
2 stops
$434Multiple Airlines
Thu, Feb 12 - Tue, Feb 17
JetBlue Logo
11:55 am - 6:43 pm
TPA
-
MAZ
6h 48m
1 stop
JetBlue Logo
4:36 pm - 12:13 am
MAZ
-
TPA
7h 37m
1 stop
$493JetBlue
Mon, May 11 - Wed, May 13
JetBlue Logo
6:00 am - 12:44 pm
TPA
-
MAZ
5h 44m
1 stop
JetBlue Logo
4:36 pm - 10:45 pm
MAZ
-
TPA
7h 09m
1 stop
$563JetBlue
Sat, Jan 24 - Fri, Jan 30
JetBlue Logo
11:55 am - 6:43 pm
TPA
-
MAZ
6h 48m
1 stop
JetBlue Logo
4:36 pm - 12:13 am
MAZ
-
TPA
7h 37m
1 stop
$568JetBlue
Mon, May 11 - Wed, May 13
JetBlue Logo
6:00 am - 12:44 pm
TPA
-
MAZ
5h 44m
1 stop
JetBlue Logo
4:36 pm - 10:45 pm
MAZ
-
TPA
7h 09m
1 stop
$583JetBlue
Sat, Jan 24 - Fri, Jan 30
JetBlue Logo
6:00 am - 12:44 pm
TPA
-
MAZ
6h 44m
1 stop
JetBlue Logo
10:07 am - 5:20 pm
MAZ
-
TPA
7h 13m
1 stop
$658JetBlue
Wed, Mar 25 - Mon, Apr 6
Multiple Airlines Logo
6:00 am - 12:44 pm
TPA
-
MAZ
5h 44m
1 stop
Multiple Airlines Logo
4:36 pm - 8:16 am
MAZ
-
TPA
16h 40m
1 stop
$734Multiple Airlines
Thu, Feb 12 - Tue, Feb 17
Multiple Airlines Logo
8:00 am - 9:42 am
TPA
-
MAZ
24h 42m
2 stops
Multiple Airlines Logo
7:35 am - 9:06 pm
MAZ
-
TPA
14h 31m
2 stops
$860Multiple Airlines
Thu, Feb 12 - Tue, Feb 17
United Airlines Logo
7:08 pm - 4:11 pm
TPA
-
MAZ
20h 03m
2 stops
United Airlines Logo
1:19 pm - 11:10 am
MAZ
-
TPA
21h 51m
2 stops
$1,685United Airlines
Thu, Mar 5 - Mon, Mar 9
United Airlines Logo
7:08 pm - 4:11 pm
TPA
-
MAZ
20h 03m
2 stops
United Airlines Logo
1:19 pm - 3:34 pm
MAZ
-
TPA
26h 15m
3 stops
$1,719United Airlines
Thu, Mar 5 - Mon, Mar 9

JetBlue flights from Tampa to Mayagüez

Our best JetBlue deals on Tampa to Mayagüez flight tickets
JetBlue
May 11
TPA11:55 amTampa
6h 48m
1 stop
MAZ6:43 pmMayagüez Eugenio M De Hostos
May 13
MAZ4:36 pmMayagüez Eugenio M De Hostos
7h 37m
1 stop
TPA12:13 amTampa
$493
JetBlue
Jan 24
TPA6:00 amTampa
5h 44m
1 stop
MAZ12:44 pmMayagüez Eugenio M De Hostos
Jan 30
MAZ4:36 pmMayagüez Eugenio M De Hostos
7h 09m
1 stop
TPA10:45 pmTampa
$563
JetBlue
May 11
TPA11:55 amTampa
6h 48m
1 stop
MAZ6:43 pmMayagüez Eugenio M De Hostos
May 13
MAZ4:36 pmMayagüez Eugenio M De Hostos
7h 37m
1 stop
TPA12:13 amTampa
$568

United Airlines flights from Tampa to Mayagüez

Our best United Airlines deals on Tampa to Mayagüez flight tickets
United Airlines
Mar 5
TPA7:08 pmTampa
20h 03m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Mar 9
MAZ1:19 pmMayagüez Eugenio M De Hostos
21h 51m
2 stops
TPA11:10 amTampa
$1,685
United Airlines
Mar 5
TPA7:08 pmTampa
20h 03m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Mar 9
MAZ1:19 pmMayagüez Eugenio M De Hostos
26h 15m
3 stops
TPA3:34 pmTampa
$1,719
United Airlines
May 11
TPA7:01 pmTampa
21h 10m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
May 13
MAZ1:19 pmMayagüez Eugenio M De Hostos
21h 50m
2 stops
TPA11:09 amTampa
$1,821

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Tampa to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Thu 2/12

10:34 pm-9:42 am

1 stop10h 08m

Mayagüez Eugenio M De Hostos

Tue 2/17

1:19 pm-4:46 pm

2 stops28h 27m

$434

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 5/11

11:55 am-6:43 pm

1 stop6h 48m

Mayagüez Eugenio M De Hostos

Wed 5/13

4:36 pm-12:13 am

1 stop7h 37m

$493

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sat 1/24

6:00 am-12:44 pm

1 stop5h 44m

Mayagüez Eugenio M De Hostos

Fri 1/30

4:36 pm-10:45 pm

1 stop7h 09m

$563

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 5/11

11:55 am-6:43 pm

1 stop6h 48m

Mayagüez Eugenio M De Hostos

Wed 5/13

4:36 pm-12:13 am

1 stop7h 37m

$568

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sat 1/24

6:00 am-12:44 pm

1 stop5h 44m

Mayagüez Eugenio M De Hostos

Fri 1/30

4:36 pm-10:45 pm

1 stop7h 09m

$583

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Wed 3/25

6:00 am-12:44 pm

1 stop6h 44m

Mayagüez Eugenio M De Hostos

Mon 4/6

10:07 am-5:20 pm

1 stop7h 13m

$658

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Thu 2/12

6:00 am-12:44 pm

1 stop5h 44m

Mayagüez Eugenio M De Hostos

Tue 2/17

4:36 pm-8:16 am

1 stop16h 40m

$734

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Thu 2/12

8:00 am-9:42 am

2 stops24h 42m

Mayagüez Eugenio M De Hostos

Tue 2/17

7:35 am-9:06 pm

2 stops14h 31m

$860

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Thu 3/5

7:08 pm-4:11 pm

2 stops20h 03m

Mayagüez Eugenio M De Hostos

Mon 3/9

1:19 pm-11:10 am

2 stops21h 51m

$1,685

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Thu 3/5

7:08 pm-4:11 pm

2 stops20h 03m

Mayagüez Eugenio M De Hostos

Mon 3/9

1:19 pm-3:34 pm

3 stops26h 15m

$1,719

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Mayagüez from

How to get the cheapest flight ticket from Tampa to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Mayagüez?

Frontier, JetBlue and Spirit Airlines are the top three most popular airlines that fly to Mayagüez from Tampa according to our data. Frontier is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 8 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

When to book flights from Tampa to Mayagüez

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Mayagüez according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Mayagüez (TPA to MAZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Mayagüez

Fastest flight time

5h 44m

Direct flights

None
The fastest flight from Tampa to Mayagüez takes 5h 44m
There are no direct flights from Tampa to Mayagüez. There are no popular flight routes from Tampa to Mayagüez.
Search flight deals

  • How far is Tampa to Mayagüez Eugenio M De Hostos by plane?

    Mayagüez Eugenio M De Hostos is 1181.4 mi away from Tampa. 5h 44m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport refresh daily.

  • How old do you have to be to fly from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The travel and health documents required for your trip to Mayagüez Eugenio M De Hostos Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mayagüez Eugenio M De Hostos Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Mayagüez?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Mayagüez for you.

Can I find flights from Tampa to Mayagüez with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Tampa to Mayagüez flights to just show those with flexible booking policies.

How can momondo help me find flights from Tampa to Mayagüez?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mayagüez from Tampa.

I’m not ready to book a flight from Tampa to Mayagüez right now. Can momondo alert me if prices change?

Price alerts on flights to Mayagüez from Tampa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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