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Cheap flights from Tampa to Mayagüez from $374

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Mayagüez departing on 6/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Tampa to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:35 pm - 9:42 am
TPA
-
MAZ
12h 07m
1 stop
Multiple Airlines Logo
7:35 am - 8:30 pm
MAZ
-
TPA
12h 55m
1 stop
$473Multiple Airlines
Wed, Jul 8 - Wed, Jul 15
JetBlue Logo
11:05 am - 6:43 pm
TPA
-
MAZ
7h 38m
1 stop
JetBlue Logo
7:35 am - 3:48 pm
MAZ
-
TPA
8h 13m
1 stop
$528JetBlue
Sun, Aug 9 - Thu, Aug 13
JetBlue Logo
11:05 am - 4:11 pm
TPA
-
MAZ
5h 06m
1 stop
JetBlue Logo
10:07 am - 3:48 pm
MAZ
-
TPA
5h 41m
1 stop
$548JetBlue
Sun, Aug 9 - Thu, Aug 13
JetBlue Logo
11:05 am - 6:43 pm
TPA
-
MAZ
7h 38m
1 stop
JetBlue Logo
7:35 am - 3:48 pm
MAZ
-
TPA
8h 13m
1 stop
$553JetBlue
Sun, Aug 9 - Thu, Aug 13
JetBlue Logo
1:50 pm - 6:43 pm
TPA
-
MAZ
4h 53m
1 stop
JetBlue Logo
7:35 am - 12:31 pm
MAZ
-
TPA
4h 56m
1 stop
$578JetBlue
Thu, Sep 10 - Thu, Sep 17
Multiple Airlines Logo
11:05 am - 4:11 pm
TPA
-
MAZ
5h 06m
1 stop
Multiple Airlines Logo
4:36 pm - 12:49 am
MAZ
-
TPA
8h 13m
1 stop
$589Multiple Airlines
Mon, Jun 15 - Fri, Jun 19
JetBlue Logo
11:05 am - 6:43 pm
TPA
-
MAZ
7h 38m
1 stop
JetBlue Logo
7:35 am - 4:46 pm
MAZ
-
TPA
9h 11m
2 stops
$810JetBlue
Wed, Jul 8 - Wed, Jul 15
United Airlines Logo
6:15 am - 4:11 pm
TPA
-
MAZ
9h 56m
2 stops
United Airlines Logo
1:19 pm - 11:11 am
MAZ
-
TPA
21h 52m
2 stops
$1,683United Airlines
Sat, Oct 10 - Mon, Oct 19
United Airlines Logo
6:15 am - 4:11 pm
TPA
-
MAZ
9h 56m
2 stops
United Airlines Logo
1:19 pm - 3:24 pm
MAZ
-
TPA
26h 05m
3 stops
$1,703United Airlines
Sat, Oct 10 - Mon, Oct 19
United Airlines Logo
6:15 am - 4:11 pm
TPA
-
MAZ
9h 56m
2 stops
United Airlines Logo
1:19 pm - 11:11 am
MAZ
-
TPA
21h 52m
2 stops
$1,708United Airlines
Sat, Oct 10 - Sat, Oct 17

JetBlue flights from Tampa to Mayagüez

Our best JetBlue deals on Tampa to Mayagüez flight tickets
JetBlue
Aug 9
TPA11:05 amTampa
7h 38m
1 stop
MAZ6:43 pmMayagüez Eugenio M De Hostos
Aug 13
MAZ7:35 amMayagüez Eugenio M De Hostos
8h 13m
1 stop
TPA3:48 pmTampa
$528
JetBlue
Aug 9
TPA11:05 amTampa
5h 06m
1 stop
MAZ4:11 pmMayagüez Eugenio M De Hostos
Aug 13
MAZ10:07 amMayagüez Eugenio M De Hostos
5h 41m
1 stop
TPA3:48 pmTampa
$548
JetBlue
Aug 9
TPA11:05 amTampa
7h 38m
1 stop
MAZ6:43 pmMayagüez Eugenio M De Hostos
Aug 13
MAZ7:35 amMayagüez Eugenio M De Hostos
8h 13m
1 stop
TPA3:48 pmTampa
$553

United Airlines flights from Tampa to Mayagüez

Our best United Airlines deals on Tampa to Mayagüez flight tickets
United Airlines
Oct 10
TPA6:15 amTampa
9h 56m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Oct 19
MAZ1:19 pmMayagüez Eugenio M De Hostos
21h 52m
2 stops
TPA11:11 amTampa
$1,683
United Airlines
Oct 10
TPA6:15 amTampa
9h 56m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Oct 19
MAZ1:19 pmMayagüez Eugenio M De Hostos
26h 05m
3 stops
TPA3:24 pmTampa
$1,703
United Airlines
Oct 10
TPA6:15 amTampa
9h 56m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Oct 17
MAZ1:19 pmMayagüez Eugenio M De Hostos
21h 52m
2 stops
TPA11:11 amTampa
$1,708

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 1, 2026.
Use the filters below to find and compare flights from Tampa to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Wed 7/8

9:35 pm-9:42 am

1 stop12h 07m

Mayagüez Eugenio M De Hostos

Wed 7/15

7:35 am-8:30 pm

1 stop12h 55m

$473

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 8/9

11:05 am-6:43 pm

1 stop7h 38m

Mayagüez Eugenio M De Hostos

Thu 8/13

7:35 am-3:48 pm

1 stop8h 13m

$528

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 8/9

11:05 am-4:11 pm

1 stop5h 06m

Mayagüez Eugenio M De Hostos

Thu 8/13

10:07 am-3:48 pm

1 stop5h 41m

$548

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 8/9

11:05 am-6:43 pm

1 stop7h 38m

Mayagüez Eugenio M De Hostos

Thu 8/13

7:35 am-3:48 pm

1 stop8h 13m

$553
Quickest round-trip

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Thu 9/10

1:50 pm-6:43 pm

1 stop4h 53m

Mayagüez Eugenio M De Hostos

Thu 9/17

7:35 am-12:31 pm

1 stop4h 56m

$578

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 6/15

11:05 am-4:11 pm

1 stop5h 06m

Mayagüez Eugenio M De Hostos

Fri 6/19

4:36 pm-12:49 am

1 stop8h 13m

$589

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Wed 7/8

11:05 am-6:43 pm

1 stop7h 38m

Mayagüez Eugenio M De Hostos

Wed 7/15

7:35 am-4:46 pm

2 stops9h 11m

$810

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sat 10/10

6:15 am-4:11 pm

2 stops9h 56m

Mayagüez Eugenio M De Hostos

Mon 10/19

1:19 pm-11:11 am

2 stops21h 52m

$1,683

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sat 10/10

6:15 am-4:11 pm

2 stops9h 56m

Mayagüez Eugenio M De Hostos

Mon 10/19

1:19 pm-3:24 pm

3 stops26h 05m

$1,703

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sat 10/10

6:15 am-4:11 pm

2 stops9h 56m

Mayagüez Eugenio M De Hostos

Sat 10/17

1:19 pm-11:11 am

2 stops21h 52m

$1,708

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Mayagüez from

How to get the cheapest flight ticket from Tampa to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Tampa to Mayagüez Eugenio M De Hostos?

JetBlue and United Airlines are the most popular carriers operating from Tampa to Mayagüez Eugenio M De Hostos

What airlines fly to Mayagüez?

Frontier, JetBlue and Spirit Airlines are the top three most popular airlines that fly to Mayagüez from Tampa according to our data. Frontier is the first choice among our users, with 49% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 7 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

When to book flights from Tampa to Mayagüez

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Mayagüez according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Mayagüez (TPA to MAZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Mayagüez

Fastest flight time

5h 06m

Direct flights

None
The fastest flight from Tampa to Mayagüez takes 5h 06m
There are no direct flights from Tampa to Mayagüez. There are no popular flight routes from Tampa to Mayagüez.
Search flight deals

Frequently asked questions about flying from Tampa to Mayagüez

  • How far is Tampa to Mayagüez Eugenio M De Hostos by plane?

    Mayagüez Eugenio M De Hostos is 1181.4 mi away from Tampa. 5h 06m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport refresh daily.

  • How old do you have to be to fly from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The travel and health documents required for your trip to Mayagüez Eugenio M De Hostos Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mayagüez Eugenio M De Hostos Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Mayagüez?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Mayagüez for you.

Can I find flights from Tampa to Mayagüez with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Tampa to Mayagüez flights to just show those with flexible booking policies.

How can momondo help me find flights from Tampa to Mayagüez?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mayagüez from Tampa.

I’m not ready to book a flight from Tampa to Mayagüez right now. Can momondo alert me if prices change?

Price alerts on flights to Mayagüez from Tampa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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