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Cheap flights from Tampa to Mayagüez from $375

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Mayagüez departing on 5/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Tampa to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:57 pm - 9:42 am
TPA
-
MAZ
12h 45m
1 stop
Multiple Airlines Logo
7:05 am - 5:21 pm
MAZ
-
TPA
10h 16m
2 stops
$375Multiple Airlines
Sun, May 24 - Tue, Jun 2
Multiple Airlines Logo
11:00 am - 9:42 am
TPA
-
MAZ
22h 42m
1 stop
Multiple Airlines Logo
1:19 pm - 7:30 am
MAZ
-
TPA
18h 11m
2 stops
$394Multiple Airlines
Tue, May 12 - Mon, May 18
Multiple Airlines Logo
11:00 am - 9:42 am
TPA
-
MAZ
22h 42m
1 stop
Multiple Airlines Logo
4:36 pm - 7:30 am
MAZ
-
TPA
14h 54m
2 stops
$406Multiple Airlines
Tue, May 12 - Mon, May 18
Multiple Airlines Logo
8:57 pm - 9:42 am
TPA
-
MAZ
12h 45m
1 stop
Multiple Airlines Logo
4:13 pm - 8:02 pm
MAZ
-
TPA
27h 49m
1 stop
$431Multiple Airlines
Sun, May 24 - Tue, Jun 2
Multiple Airlines Logo
11:00 am - 9:42 am
TPA
-
MAZ
22h 42m
1 stop
Multiple Airlines Logo
4:36 pm - 6:17 pm
MAZ
-
TPA
25h 41m
1 stop
$482Multiple Airlines
Tue, May 12 - Mon, May 18
Multiple Airlines Logo
11:00 am - 9:42 am
TPA
-
MAZ
22h 42m
1 stop
Multiple Airlines Logo
7:35 am - 8:00 pm
MAZ
-
TPA
12h 25m
1 stop
$488Multiple Airlines
Tue, May 12 - Mon, May 18
JetBlue Logo
9:06 pm - 8:44 am
TPA
-
MAZ
11h 38m
1 stop
JetBlue Logo
1:25 pm - 11:28 pm
MAZ
-
TPA
10h 03m
1 stop
$568JetBlue
Tue, Jul 7 - Tue, Jul 14
JetBlue Logo
9:07 pm - 8:44 am
TPA
-
MAZ
11h 37m
1 stop
JetBlue Logo
4:13 pm - 11:28 pm
MAZ
-
TPA
7h 15m
1 stop
$603JetBlue
Wed, Jun 17 - Mon, Jun 22
Multiple Airlines Logo
7:00 am - 4:11 pm
TPA
-
MAZ
9h 11m
2 stops
Multiple Airlines Logo
4:36 pm - 9:27 am
MAZ
-
TPA
16h 51m
2 stops
$627Multiple Airlines
Tue, May 12 - Mon, May 18
JetBlue Logo
5:01 am - 12:44 pm
TPA
-
MAZ
7h 43m
1 stop
JetBlue Logo
1:19 pm - 6:19 pm
MAZ
-
TPA
5h 00m
1 stop
$673JetBlue
Thu, Apr 30 - Mon, May 4

JetBlue flights from Tampa to Mayagüez

Our best JetBlue deals on Tampa to Mayagüez flight tickets
JetBlue
Jul 7
TPA9:06 pmTampa
11h 38m
1 stop
MAZ8:44 amMayagüez Eugenio M De Hostos
Jul 14
MAZ1:25 pmMayagüez Eugenio M De Hostos
10h 03m
1 stop
TPA11:28 pmTampa
$568
JetBlue
Jun 17
TPA9:07 pmTampa
11h 37m
1 stop
MAZ8:44 amMayagüez Eugenio M De Hostos
Jun 22
MAZ4:13 pmMayagüez Eugenio M De Hostos
7h 15m
1 stop
TPA11:28 pmTampa
$603
JetBlue
Apr 30
TPA5:01 amTampa
7h 43m
1 stop
MAZ12:44 pmMayagüez Eugenio M De Hostos
May 4
MAZ1:19 pmMayagüez Eugenio M De Hostos
5h 00m
1 stop
TPA6:19 pmTampa
$673

United Airlines flights from Tampa to Mayagüez

Our best United Airlines deals on Tampa to Mayagüez flight tickets
United Airlines
May 1
TPA6:00 amTampa
10h 11m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
May 4
MAZ1:19 pmMayagüez Eugenio M De Hostos
21h 55m
2 stops
TPA11:14 amTampa
$1,128
United Airlines
May 1
TPA6:00 amTampa
10h 11m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
May 4
MAZ1:19 pmMayagüez Eugenio M De Hostos
26h 09m
3 stops
TPA3:28 pmTampa
$1,146
United Airlines
Apr 30
TPA6:57 pmTampa
21h 14m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
May 4
MAZ1:19 pmMayagüez Eugenio M De Hostos
21h 55m
2 stops
TPA11:14 amTampa
$1,253

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Tampa to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 5/24

8:57 pm-9:42 am

1 stop12h 45m

Mayagüez Eugenio M De Hostos

Tue 6/2

7:05 am-5:21 pm

2 stops10h 16m

$375

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Tue 5/12

11:00 am-9:42 am

1 stop22h 42m

Mayagüez Eugenio M De Hostos

Mon 5/18

1:19 pm-7:30 am

2 stops18h 11m

$394

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Tue 5/12

11:00 am-9:42 am

1 stop22h 42m

Mayagüez Eugenio M De Hostos

Mon 5/18

4:36 pm-7:30 am

2 stops14h 54m

$406

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 5/24

8:57 pm-9:42 am

1 stop12h 45m

Mayagüez Eugenio M De Hostos

Tue 6/2

4:13 pm-8:02 pm

1 stop27h 49m

$431

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Tue 5/12

11:00 am-9:42 am

1 stop22h 42m

Mayagüez Eugenio M De Hostos

Mon 5/18

4:36 pm-6:17 pm

1 stop25h 41m

$482

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Tue 5/12

11:00 am-9:42 am

1 stop22h 42m

Mayagüez Eugenio M De Hostos

Mon 5/18

7:35 am-8:00 pm

1 stop12h 25m

$488

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Tue 7/7

9:06 pm-8:44 am

1 stop11h 38m

Mayagüez Eugenio M De Hostos

Tue 7/14

1:25 pm-11:28 pm

1 stop10h 03m

$568

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Wed 6/17

9:07 pm-8:44 am

1 stop11h 37m

Mayagüez Eugenio M De Hostos

Mon 6/22

4:13 pm-11:28 pm

1 stop7h 15m

$603

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Tue 5/12

7:00 am-4:11 pm

2 stops9h 11m

Mayagüez Eugenio M De Hostos

Mon 5/18

4:36 pm-9:27 am

2 stops16h 51m

$627
Quickest round-trip

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Thu 4/30

5:01 am-12:44 pm

1 stop7h 43m

Mayagüez Eugenio M De Hostos

Mon 5/4

1:19 pm-6:19 pm

1 stop5h 00m

$673

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Mayagüez from

How to get the cheapest flight ticket from Tampa to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Tampa to Mayagüez Eugenio M De Hostos?

United Airlines is the most popular carrier operating from Tampa to Mayagüez Eugenio M De Hostos

What airlines fly to Mayagüez?

Frontier, JetBlue and Spirit Airlines are the top three most popular airlines that fly to Mayagüez from Tampa according to our data. Frontier is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 7 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

When to book flights from Tampa to Mayagüez

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Mayagüez according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Mayagüez (TPA to MAZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Mayagüez

Fastest flight time

7h 13m

Direct flights

None
The fastest flight from Tampa to Mayagüez takes 7h 13m
There are no direct flights from Tampa to Mayagüez. There are no popular flight routes from Tampa to Mayagüez.
Search flight deals

Frequently asked questions about flying from Tampa to Mayagüez

  • How far is Tampa to Mayagüez Eugenio M De Hostos by plane?

    Mayagüez Eugenio M De Hostos is 1181.4 mi away from Tampa. 7h 13m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport refresh daily.

  • How old do you have to be to fly from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The travel and health documents required for your trip to Mayagüez Eugenio M De Hostos Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mayagüez Eugenio M De Hostos Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Mayagüez?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Mayagüez for you.

Can I find flights from Tampa to Mayagüez with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Tampa to Mayagüez flights to just show those with flexible booking policies.

How can momondo help me find flights from Tampa to Mayagüez?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mayagüez from Tampa.

I’m not ready to book a flight from Tampa to Mayagüez right now. Can momondo alert me if prices change?

Price alerts on flights to Mayagüez from Tampa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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