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Cheap flights from Tampa to Mayagüez from $335

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Mayagüez departing on 10/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Multiple Airlines Logo
8:26 pm - 9:42 amTPA-MAZ
13h 16m1 stop
Multiple Airlines Logo
10:07 am - 5:37 pmMAZ-TPA
31h 30m2 stops
$335Multiple Airlines
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Mon, Oct 27 - Fri, Oct 31
Multiple Airlines Logo
8:26 pm - 9:42 amTPA-MAZ
13h 16m1 stop
Multiple Airlines Logo
10:07 am - 5:29 pmMAZ-TPA
7h 22m1 stop
$350Multiple Airlines
Find Deal
Mon, Oct 27 - Fri, Oct 31
Multiple Airlines Logo
8:00 am - 4:11 pmTPA-MAZ
7h 11m1 stop
Multiple Airlines Logo
4:36 pm - 11:21 pmMAZ-TPA
31h 45m2 stops
$417Multiple Airlines
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Fri, Nov 14 - Wed, Nov 19
Multiple Airlines Logo
10:38 am - 6:43 pmTPA-MAZ
7h 05m1 stop
Multiple Airlines Logo
4:36 pm - 11:21 pmMAZ-TPA
31h 45m2 stops
$428Multiple Airlines
Find Deal
Sun, Nov 16 - Wed, Nov 19
JetBlue Logo
6:00 am - 1:03 pmTPA-MAZ
7h 03m1 stop
JetBlue Logo
4:36 pm - 10:00 pmMAZ-TPA
5h 24m1 stop
$567JetBlue
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Mon, Oct 27 - Fri, Oct 31
JetBlue Logo
6:00 am - 6:43 pmTPA-MAZ
11h 43m1 stop
JetBlue Logo
4:36 pm - 9:58 pmMAZ-TPA
6h 22m1 stop
$577JetBlue
Find Deal
Sun, Nov 16 - Wed, Nov 19
JetBlue Logo
6:00 am - 1:03 pmTPA-MAZ
7h 03m1 stop
JetBlue Logo
4:35 pm - 10:14 pmMAZ-TPA
5h 39m1 stop
$617JetBlue
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Mon, Oct 27 - Tue, Oct 28
United Airlines Logo
6:50 pm - 4:15 pmTPA-MAZ
21h 25m2 stops
United Airlines Logo
1:19 pm - 7:35 pmMAZ-TPA
30h 16m2 stops
$1,824United Airlines
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Mon, Oct 27 - Fri, Oct 31
United Airlines Logo
6:50 pm - 4:11 pmTPA-MAZ
20h 21m2 stops
United Airlines Logo
1:19 pm - 6:13 pmMAZ-TPA
29h 54m3 stops
$1,885United Airlines
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Wed, Nov 19 - Sun, Nov 23
United Airlines Logo
6:00 am - 4:15 pmTPA-MAZ
10h 15m2 stops
United Airlines Logo
1:19 pm - 8:26 pmMAZ-TPA
31h 07m3 stops
$1,917United Airlines
Find Deal
Mon, Oct 27 - Fri, Oct 31

JetBlue flights from Tampa to Mayagüez

Our best JetBlue deals on Tampa to Mayagüez flight tickets
JetBlue
Oct 27
TPA6:00 amTampa
7h 03m
1 stop
MAZ1:03 pmMayagüez Eugenio M De Hostos
Oct 31
MAZ4:36 pmMayagüez Eugenio M De Hostos
5h 24m
1 stop
TPA10:00 pmTampa
$567
Find similar
JetBlue
Nov 16
TPA6:00 amTampa
11h 43m
1 stop
MAZ6:43 pmMayagüez Eugenio M De Hostos
Nov 19
MAZ4:36 pmMayagüez Eugenio M De Hostos
6h 22m
1 stop
TPA9:58 pmTampa
$577
Find similar
JetBlue
Oct 27
TPA6:00 amTampa
7h 03m
1 stop
MAZ1:03 pmMayagüez Eugenio M De Hostos
Oct 28
MAZ4:35 pmMayagüez Eugenio M De Hostos
5h 39m
1 stop
TPA10:14 pmTampa
$617
Find similar

United Airlines flights from Tampa to Mayagüez

Our best United Airlines deals on Tampa to Mayagüez flight tickets
United Airlines
Oct 27
TPA6:50 pmTampa
21h 25m
2 stops
MAZ4:15 pmMayagüez Eugenio M De Hostos
Oct 31
MAZ1:19 pmMayagüez Eugenio M De Hostos
30h 16m
2 stops
TPA7:35 pmTampa
$1,824
Find similar
United Airlines
Nov 19
TPA6:50 pmTampa
20h 21m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Nov 23
MAZ1:19 pmMayagüez Eugenio M De Hostos
29h 54m
3 stops
TPA6:13 pmTampa
$1,885
Find similar
United Airlines
Oct 27
TPA6:00 amTampa
10h 15m
2 stops
MAZ4:15 pmMayagüez Eugenio M De Hostos
Oct 31
MAZ1:19 pmMayagüez Eugenio M De Hostos
31h 07m
3 stops
TPA8:26 pmTampa
$1,917
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Tampa to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 10/27

8:26 pm-9:42 am

1 stop13h 16m

Mayagüez Eugenio M De Hostos

Fri 10/31

10:07 am-5:37 pm

2 stops31h 30m

$335

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 10/27

8:26 pm-9:42 am

1 stop13h 16m

Mayagüez Eugenio M De Hostos

Fri 10/31

10:07 am-5:29 pm

1 stop7h 22m

$350

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Fri 11/14

8:00 am-4:11 pm

1 stop7h 11m

Mayagüez Eugenio M De Hostos

Wed 11/19

4:36 pm-11:21 pm

2 stops31h 45m

$417

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 11/16

10:38 am-6:43 pm

1 stop7h 05m

Mayagüez Eugenio M De Hostos

Wed 11/19

4:36 pm-11:21 pm

2 stops31h 45m

$428

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 10/27

6:00 am-1:03 pm

1 stop7h 03m

Mayagüez Eugenio M De Hostos

Fri 10/31

4:36 pm-10:00 pm

1 stop5h 24m

$567

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Sun 11/16

6:00 am-6:43 pm

1 stop11h 43m

Mayagüez Eugenio M De Hostos

Wed 11/19

4:36 pm-9:58 pm

1 stop6h 22m

$577

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 10/27

6:00 am-1:03 pm

1 stop7h 03m

Mayagüez Eugenio M De Hostos

Tue 10/28

4:35 pm-10:14 pm

1 stop5h 39m

$617

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 10/27

6:50 pm-4:15 pm

2 stops21h 25m

Mayagüez Eugenio M De Hostos

Fri 10/31

1:19 pm-7:35 pm

2 stops30h 16m

$1,824

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Wed 11/19

6:50 pm-4:11 pm

2 stops20h 21m

Mayagüez Eugenio M De Hostos

Sun 11/23

1:19 pm-6:13 pm

3 stops29h 54m

$1,885

TampaMayagüez

TPA - MAZ

TPAMAZ

Tampa

Mon 10/27

6:00 am-4:15 pm

2 stops10h 15m

Mayagüez Eugenio M De Hostos

Fri 10/31

1:19 pm-8:26 pm

3 stops31h 07m

$1,917

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Mayagüez from

How to get the cheapest flight ticket from Tampa to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Tampa to Mayagüez Eugenio M De Hostos?

JetBlue and United Airlines are the most popular carriers operating from Tampa to Mayagüez Eugenio M De Hostos

What airlines fly to Mayagüez?

Frontier, JetBlue and Spirit Airlines are the top three most popular airlines that fly to Mayagüez from Tampa according to our data. Frontier is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 8 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

When to book flights from Tampa to Mayagüez

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Mayagüez according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Mayagüez (TPA to MAZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Mayagüez

Direct flights

None
There are no direct flights from Tampa to Mayagüez. There are no popular flight routes from Tampa to Mayagüez.
Search flight deals

  • How far is Tampa to Mayagüez Eugenio M De Hostos by plane?

    Mayagüez Eugenio M De Hostos is 1181.4 mi away from Tampa. 5h 44m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Tampa Airport to Mayagüez Eugenio M De Hostos Airport refresh daily.

  • How old do you have to be to fly from Tampa Airport to Mayagüez Eugenio M De Hostos Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The travel and health documents required for your trip to Mayagüez Eugenio M De Hostos Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mayagüez Eugenio M De Hostos Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Mayagüez?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Mayagüez for you.

Can I find flights from Tampa to Mayagüez with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Tampa to Mayagüez flights to just show those with flexible booking policies.

How can momondo help me find flights from Tampa to Mayagüez?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mayagüez from Tampa.

I’m not ready to book a flight from Tampa to Mayagüez right now. Can momondo alert me if prices change?

Price alerts on flights to Mayagüez from Tampa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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