What is the cheapest airline that flies from Tampa to Florence?

American Airlines is the most popular carrier operating from Tampa to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Spirit Airlines and Frontier are the top three most popular airlines that fly to Florence, South Carolina from Tampa according to our data. American Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 7 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Tampa Airport to Florence Airport?

Prices for flights from Tampa Airport to Florence Airport were last updated today.

How old do you have to be to fly from Tampa Airport to Florence Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Tampa Airport to Florence Airport.

What documentation or ID do you need to fly to Florence Airport?

The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$278 Cheap Flights from Tampa to Florence in 2025/26

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Find the cheapest flights from Tampa to Florence

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

12:09 pm - 10:43 pm

TPA

FLO

10h 34m2 stops

6:15 am - 4:35 pm

FLO

TPA

10h 20m2 stops

$410American Airlines

Mon, Feb 2 - Mon, Feb 9

4:50 pm - 10:43 pm

TPA

FLO

5h 53m1 stop

6:15 am - 4:35 pm

FLO

TPA

10h 20m2 stops

$422American Airlines

Fri, Jan 16 - Mon, Jan 19

12:09 pm - 10:43 pm

TPA

FLO

10h 34m2 stops

6:15 am - 4:35 pm

FLO

TPA

10h 20m2 stops

$423American Airlines

Fri, Jan 16 - Mon, Jan 19

4:50 pm - 10:43 pm

TPA

FLO

5h 53m1 stop

5:36 pm - 11:24 pm

FLO

TPA

5h 48m1 stop

$435American Airlines

Fri, Jan 16 - Mon, Jan 19

1:50 pm - 5:49 pm

TPA

FLO

3h 59m1 stop

6:15 am - 12:26 pm

FLO

TPA

6h 11m1 stop

$447American Airlines

Sat, Feb 14 - Wed, Feb 18

12:07 pm - 5:49 pm

TPA

FLO

5h 42m1 stop

6:15 am - 3:41 pm

FLO

TPA

9h 26m2 stops

$452American Airlines

Sat, Feb 14 - Wed, Feb 18

6:00 am - 12:26 pm

TPA

FLO

6h 26m1 stop

6:30 pm - 10:00 pm

FLO

TPA

3h 30m1 stop

$517American Airlines

Thu, Dec 18 - Mon, Dec 22

2:24 pm - 12:15 am

TPA

FLO

9h 51m2 stops

5:15 am - 10:45 am

FLO

TPA

5h 30m1 stop

$522American Airlines

Thu, Dec 18 - Mon, Dec 22

9:23 am - 6:05 pm

TPA

FLO

8h 42m2 stops

5:15 am - 1:01 pm

FLO

TPA

7h 46m2 stops

$527American Airlines

Thu, Dec 18 - Mon, Dec 22

American Airlines flights from Tampa to Florence, South Carolina

Our best American Airlines deals on Tampa to Florence, South Carolina flight tickets

American Airlines

Feb 2

TPA12:09 pmTampa

10h 34m

2 stops

FLO10:43 pmFlorence

Feb 9

FLO6:15 amFlorence

10h 20m

2 stops

TPA4:35 pmTampa

$410

Find similar

American Airlines

Jan 16

TPA4:50 pmTampa

5h 53m

1 stop

FLO10:43 pmFlorence

Jan 19

FLO6:15 amFlorence

10h 20m

2 stops

TPA4:35 pmTampa

$422

Find similar

American Airlines

Jan 16

TPA12:09 pmTampa

10h 34m

2 stops

FLO10:43 pmFlorence

Jan 19

FLO6:15 amFlorence

10h 20m

2 stops

TPA4:35 pmTampa

$423

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Tampa to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Mon 2/2

12:09 pm-10:43 pm

2 stops10h 34m

Florence

Mon 2/9

6:15 am-4:35 pm

2 stops10h 20m

$410

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Fri 1/16

4:50 pm-10:43 pm

1 stop5h 53m

Florence

Mon 1/19

6:15 am-4:35 pm

2 stops10h 20m

$422

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Fri 1/16

12:09 pm-10:43 pm

2 stops10h 34m

Florence

Mon 1/19

6:15 am-4:35 pm

2 stops10h 20m

$423

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Fri 1/16

4:50 pm-10:43 pm

1 stop5h 53m

Florence

Mon 1/19

5:36 pm-11:24 pm

1 stop5h 48m

$435

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Sat 2/14

1:50 pm-5:49 pm

1 stop3h 59m

Florence

Wed 2/18

6:15 am-12:26 pm

1 stop6h 11m

$447

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Sat 2/14

12:07 pm-5:49 pm

1 stop5h 42m

Florence

Wed 2/18

6:15 am-3:41 pm

2 stops9h 26m

$452

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Thu 12/18

6:00 am-12:26 pm

1 stop6h 26m

Florence

Mon 12/22

6:30 pm-10:00 pm

1 stop3h 30m

$517

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Thu 12/18

2:24 pm-12:15 am

2 stops9h 51m

Florence

Mon 12/22

5:15 am-10:45 am

1 stop5h 30m

$522

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Thu 12/18

9:23 am-6:05 pm

2 stops8h 42m

Florence

Mon 12/22

5:15 am-1:01 pm

2 stops7h 46m

$527

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Sat 12/20

5:20 pm-12:15 am

1 stop6h 55m

$362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Tampa to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Tampa is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $341. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Thursday is the most expensive day to depart from Tampa because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $646.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the morning. momondo users have found flights departing from Tampa to Florence, South Carolina in the morning for as low as $366. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the afternoon is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $593 per ticket.

When to book flights from Tampa to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Tampa to Florence, South Carolina (TPA to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Florence, South Carolina

Fastest flight time	4h 22m
Direct flights	None

The fastest flight from Tampa to Florence, South Carolina takes 4h 22m

There are no direct flights from Tampa to Florence, South Carolina. There are no popular flight routes from Tampa to Florence, South Carolina.

Search flight deals

How far is Tampa to Florence by plane?
Tampa and Florence are 459.5 mi apart from one another. Typically, this will take 3h 59m by plane in normal conditions.
When did momondo last update prices for flights from Tampa Airport to Florence Airport?
Prices for flights from Tampa Airport to Florence Airport were last updated today.
How old do you have to be to fly from Tampa Airport to Florence Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Tampa Airport to Florence Airport.
What documentation or ID do you need to fly to Florence Airport?
The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Sumter

Lake City

Hartsville

Bennettsville

Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Florence?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Tampa to Florence. momondo saves you time and could save you money on your trip.

Can I find flights from Tampa to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Tampa with this policy.

How can momondo help me find flights from Tampa to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Tampa to Florence.

I’m not ready to book a flight from Tampa to Florence right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florence, momondo offers a useful price alert feature which will track prices for flights to Florence from Tampa and alert you when they change.