When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Florence Airport?

Prices for flights from Syracuse Hancock Intl Airport to Florence Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Florence Airport?

As of December 2025, there is 1 operator available to choose from for flights from Syracuse Hancock Intl Airport to Florence Airport.

How old do you have to be to fly from Syracuse Hancock Intl Airport to Florence Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Florence Airport.

What documentation or ID do you need to fly to Florence Airport?

The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$481 Cheap Flights from Syracuse to Florence in 2025/26

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Find the cheapest flights from Syracuse to Florence

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:09 pm - 11:58 pm

SYR

FLO

5h 49m1 stop

6:18 pm - 12:28 am

FLO

SYR

6h 10m1 stop

$481American Airlines

Fri, Feb 27 - Sun, Mar 1

12:05 pm - 11:58 pm

SYR

FLO

11h 53m2 stops

6:18 pm - 12:28 am

FLO

SYR

6h 10m1 stop

$486American Airlines

Fri, Feb 27 - Sun, Mar 1

3:26 pm - 11:58 pm

SYR

FLO

8h 32m2 stops

5:15 am - 3:46 pm

FLO

SYR

10h 31m2 stops

$548American Airlines

Fri, Feb 27 - Sun, Mar 1

7:05 am - 12:26 pm

SYR

FLO

5h 21m1 stop

6:30 pm - 12:42 am

FLO

SYR

6h 12m1 stop

$554American Airlines

Wed, Dec 31 - Sun, Jan 4

7:05 am - 12:26 pm

SYR

FLO

5h 21m1 stop

5:15 am - 3:11 pm

FLO

SYR

9h 56m2 stops

$559American Airlines

Wed, Dec 31 - Sun, Jan 4

12:10 pm - 7:38 pm

SYR

FLO

7h 28m2 stops

5:15 am - 3:11 pm

FLO

SYR

9h 56m2 stops

$564American Airlines

Wed, Dec 31 - Sun, Jan 4

American Airlines flights from Syracuse to Florence, South Carolina

Our best American Airlines deals on Syracuse to Florence, South Carolina flight tickets

American Airlines

Feb 27

SYR6:09 pmSyracuse Hancock Intl

5h 49m

1 stop

FLO11:58 pmFlorence

Mar 1

FLO6:18 pmFlorence

6h 10m

1 stop

SYR12:28 amSyracuse Hancock Intl

$481

Find similar

American Airlines

Feb 27

SYR12:05 pmSyracuse Hancock Intl

11h 53m

2 stops

FLO11:58 pmFlorence

Mar 1

FLO6:18 pmFlorence

6h 10m

1 stop

SYR12:28 amSyracuse Hancock Intl

$486

Find similar

American Airlines

Feb 27

SYR3:26 pmSyracuse Hancock Intl

8h 32m

2 stops

FLO11:58 pmFlorence

Mar 1

FLO5:15 amFlorence

10h 31m

2 stops

SYR3:46 pmSyracuse Hancock Intl

$548

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Syracuse to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SyracuseFlorence

SYR - FLO

SYRFLO

Syracuse Hancock Intl

Fri 2/27

6:09 pm-11:58 pm

1 stop5h 49m

Florence

Sun 3/1

6:18 pm-12:28 am

1 stop6h 10m

$481

SyracuseFlorence

SYR - FLO

SYRFLO

Syracuse Hancock Intl

Fri 2/27

12:05 pm-11:58 pm

2 stops11h 53m

Florence

Sun 3/1

6:18 pm-12:28 am

1 stop6h 10m

$486

SyracuseFlorence

SYR - FLO

SYRFLO

Syracuse Hancock Intl

Fri 2/27

3:26 pm-11:58 pm

2 stops8h 32m

Florence

Sun 3/1

5:15 am-3:46 pm

2 stops10h 31m

$548

SyracuseFlorence

SYR - FLO

SYRFLO

Syracuse Hancock Intl

Wed 12/31

7:05 am-12:26 pm

1 stop5h 21m

Florence

Sun 1/4

6:30 pm-12:42 am

1 stop6h 12m

$554

SyracuseFlorence

SYR - FLO

SYRFLO

Syracuse Hancock Intl

Wed 12/31

7:05 am-12:26 pm

1 stop5h 21m

Florence

Sun 1/4

5:15 am-3:11 pm

2 stops9h 56m

$559

SyracuseFlorence

SYR - FLO

SYRFLO

Syracuse Hancock Intl

Wed 12/31

12:10 pm-7:38 pm

2 stops7h 28m

Florence

Sun 1/4

5:15 am-3:11 pm

2 stops9h 56m

$564

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Syracuse to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Breeze Airways and Delta are the top three most popular airlines that fly to Florence, South Carolina from Syracuse according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Syracuse to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Syracuse to Florence, South Carolina (SYR to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to Florence, South Carolina

Fastest flight time	5h 21m
Direct flights	None

The fastest flight from Syracuse to Florence, South Carolina takes 5h 21m

There are no direct flights from Syracuse to Florence, South Carolina. There are no popular flight routes from Syracuse to Florence, South Carolina.

Search flight deals

How far is Syracuse Hancock Intl to Florence by plane?
The straight-line distance from Syracuse Hancock Intl to Florence is 641.4 mi. In terms of flight time, this usually takes a little over 5h 21m.
When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Florence Airport?
Prices for flights from Syracuse Hancock Intl Airport to Florence Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Florence Airport?
As of December 2025, there is 1 operator available to choose from for flights from Syracuse Hancock Intl Airport to Florence Airport.
How old do you have to be to fly from Syracuse Hancock Intl Airport to Florence Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Florence Airport.
What documentation or ID do you need to fly to Florence Airport?
The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Syracuse to Florence, South Carolina?
momondo data reveals that the most frequently booked airline on the route from Syracuse to Florence, South Carolina is American Airlines, representing 100% of all bookings.

Best airlines flying from Syracuse to Florence, South Carolina

Compare and see reviews for airlines that fly from Syracuse to Florence, South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $379	Free Cancellation	Rating 7.2 11,054 reviews		Search American Airlines flights

Sumter

Lake City

Hartsville

Bennettsville

Darlington

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Why should I use momondo to find a flight deal from Syracuse to Florence?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Syracuse to Florence for you.

Can I find flights from Syracuse to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Syracuse which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Syracuse to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Syracuse to Florence.

I’m not ready to book a flight from Syracuse to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Syracuse. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.