Cheap flights from St. Louis to Massachusetts from $106

In general, December is the cheapest month to fly from St. Louis to Massachusetts. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $444. If you aren’t able to travel to Massachusetts during the month of December, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $444.

According to our data, Friday is the cheapest day to fly to Massachusetts from St. Louis. The lowest ticket price found for a Friday departure recently was $544. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Monday is the most expensive day to depart from St. Louis because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $639.

Our data shows that the cheapest St. Louis to Massachusetts flights are usually those with departure times in the evening. Our users have found flights to Massachusetts in the evening for as low as $523. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $820 on average. Flights to Massachusetts from St. Louis at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Lambert-St Louis to Boston Logan Intl for the best Lambert-St Louis - Massachusetts flight prices

You are more likely to see cheaper flights to Massachusetts from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Massachusetts for around $496 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Massachusetts from St. Louis for as low as $420 on momondo.

There are 4 cabin classes available to choose from on St. Louis to Massachusetts flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, American Airlines, and Frontier are the most popular carriers operating from Lambert-St Louis to Massachusetts

American Airlines, Southwest and Frontier are the top three most popular airlines that fly to Massachusetts from St. Louis according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Massachusetts. Keep in mind that there are 5 different airlines that fly to Massachusetts on a routine basis, so you have a few additional options to choose from.

6 flights are operational daily from St. Louis to Massachusetts as of November 2026. The most popular departure time for this route is 10:00AM, with 70% of flights per day taking off at noon.

As of November 2026, 47 flights take off from St. Louis and land in Massachusetts each week. The most common flight departure day for this route is Mon, with 17% of weekly flights taking off on this day.