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Cheap flights from St. Louis to Key West from $134

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Key West departing on 1/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from St. Louis to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:11 pm - 12:26 pm
STL
-
EYW
18h 15m1 stop
Multiple Airlines Logo
1:06 pm - 11:33 pm
EYW
-
STL
11h 27m1 stop
$185Multiple Airlines
Sun, Jan 18 - Fri, Jan 23
Multiple Airlines Logo
5:11 pm - 2:56 pm
STL
-
EYW
20h 45m1 stop
Multiple Airlines Logo
3:46 pm - 11:33 pm
EYW
-
STL
8h 47m1 stop
$186Multiple Airlines
Sat, Jan 17 - Thu, Jan 22
Multiple Airlines Logo
5:11 pm - 9:26 am
STL
-
EYW
15h 15m1 stop
Multiple Airlines Logo
10:06 am - 8:05 am
EYW
-
STL
22h 59m1 stop
$187Multiple Airlines
Wed, Jan 7 - Sun, Jan 11
Multiple Airlines Logo
5:11 pm - 9:26 am
STL
-
EYW
15h 15m1 stop
Multiple Airlines Logo
10:06 am - 9:21 am
EYW
-
STL
24h 15m1 stop
$199Multiple Airlines
Sat, Jan 17 - Sun, Jan 25
Multiple Airlines Logo
8:32 pm - 9:37 pm
STL
-
EYW
24h 05m2 stops
Multiple Airlines Logo
3:46 pm - 11:33 pm
EYW
-
STL
8h 47m1 stop
$206Multiple Airlines
Sat, Jan 17 - Thu, Jan 22
Multiple Airlines Logo
8:22 pm - 11:56 am
STL
-
EYW
14h 34m2 stops
Multiple Airlines Logo
9:46 am - 10:23 am
EYW
-
STL
25h 37m1 stop
$208Multiple Airlines
Wed, Jan 28 - Thu, Feb 5
American Airlines Logo
6:00 am - 12:35 pm
STL
-
EYW
5h 35m1 stop
American Airlines Logo
2:04 pm - 10:44 pm
EYW
-
STL
9h 40m1 stop
$220American Airlines
Tue, Jan 20 - Sat, Jan 24
Multiple Airlines Logo
5:11 pm - 11:56 am
STL
-
EYW
17h 45m2 stops
Multiple Airlines Logo
10:06 am - 8:05 am
EYW
-
STL
22h 59m1 stop
$221Multiple Airlines
Wed, Jan 7 - Sun, Jan 11
Multiple Airlines Logo
3:43 pm - 1:30 pm
STL
-
EYW
20h 47m2 stops
Multiple Airlines Logo
10:06 am - 8:05 am
EYW
-
STL
22h 59m1 stop
$222Multiple Airlines
Thu, Jan 8 - Sun, Jan 11
Multiple Airlines Logo
5:11 pm - 12:26 pm
STL
-
EYW
18h 15m1 stop
Multiple Airlines Logo
2:25 pm - 6:51 am
EYW
-
STL
17h 26m2 stops
$223Multiple Airlines
Sun, Jan 18 - Fri, Jan 23

American Airlines flights from St. Louis to Key West

Our best American Airlines deals on St. Louis to Key West flight tickets
American Airlines
Jan 20
STL6:00 amLambert-St Louis
5h 35m
1 stop
EYW12:35 pmKey West
Jan 24
EYW2:04 pmKey West
9h 40m
1 stop
STL10:44 pmLambert-St Louis
$220
Find similar
American Airlines
Mar 18
STL1:36 pmLambert-St Louis
8h 01m
1 stop
EYW10:37 pmKey West
Mar 25
EYW11:29 amKey West
7h 11m
1 stop
STL5:40 pmLambert-St Louis
$223
Find similar
American Airlines
Jan 20
STL8:13 amLambert-St Louis
9h 57m
2 stops
EYW7:10 pmKey West
Jan 24
EYW2:04 pmKey West
9h 40m
1 stop
STL10:44 pmLambert-St Louis
$225
Find similar

United Airlines flights from St. Louis to Key West

Our best United Airlines deals on St. Louis to Key West flight tickets
United Airlines
Dec 24
STL8:05 amLambert-St Louis
6h 07m
1 stop
EYW3:12 pmKey West
Dec 25
EYW12:22 pmKey West
6h 32m
1 stop
STL5:54 pmLambert-St Louis
$303
Find similar
United Airlines
Dec 24
STL8:05 amLambert-St Louis
6h 07m
1 stop
EYW3:12 pmKey West
Dec 25
EYW1:25 pmKey West
9h 18m
2 stops
STL9:43 pmLambert-St Louis
$308
Find similar
United Airlines
Dec 24
STL8:05 amLambert-St Louis
6h 07m
1 stop
EYW3:12 pmKey West
Dec 28
EYW4:29 pmKey West
6h 26m
1 stop
STL9:55 pmLambert-St Louis
$311
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from St. Louis to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 1/18

5:11 pm-12:26 pm

1 stop18h 15m

Key West

Fri 1/23

1:06 pm-11:33 pm

1 stop11h 27m

$185

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 1/17

5:11 pm-2:56 pm

1 stop20h 45m

Key West

Thu 1/22

3:46 pm-11:33 pm

1 stop8h 47m

$186

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 1/7

5:11 pm-9:26 am

1 stop15h 15m

Key West

Sun 1/11

10:06 am-8:05 am

1 stop22h 59m

$187

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 1/17

5:11 pm-9:26 am

1 stop15h 15m

Key West

Sun 1/25

10:06 am-9:21 am

1 stop24h 15m

$199

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 1/17

8:32 pm-9:37 pm

2 stops24h 05m

Key West

Thu 1/22

3:46 pm-11:33 pm

1 stop8h 47m

$206

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 1/28

8:22 pm-11:56 am

2 stops14h 34m

Key West

Thu 2/5

9:46 am-10:23 am

1 stop25h 37m

$208

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 1/20

6:00 am-12:35 pm

1 stop5h 35m

Key West

Sat 1/24

2:04 pm-10:44 pm

1 stop9h 40m

$220

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 1/7

5:11 pm-11:56 am

2 stops17h 45m

Key West

Sun 1/11

10:06 am-8:05 am

1 stop22h 59m

$221

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Thu 1/8

3:43 pm-1:30 pm

2 stops20h 47m

Key West

Sun 1/11

10:06 am-8:05 am

1 stop22h 59m

$222

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 1/18

5:11 pm-12:26 pm

1 stop18h 15m

Key West

Fri 1/23

2:25 pm-6:51 am

2 stops17h 26m

$223

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from St. Louis to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, December is the cheapest month to fly from St. Louis to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $345. If you are unable to visit Key West during the month of December, then departing from St. Louis during the month August is also very affordable. Most momondo users find prices during this month for around $353.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from St. Louis is on a Friday. momondo users have found tickets for Friday departures for as low as $376. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from St. Louis to Key West for around $557.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is at noon. momondo users have found flights departing from St. Louis to Key West at noon for as low as $394. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the afternoon, with an average ticket price of $470. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $420 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from St. Louis for as low as $319 on momondo.

When to book flights from St. Louis to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Key West (STL to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Key West

Fastest flight time

5h 14m

Direct flights

None
The fastest flight from St. Louis to Key West takes 5h 14m
There are no direct flights from St. Louis to Key West. There are no popular flight routes from St. Louis to Key West.
Search flight deals

  • How far is Lambert-St Louis to Key West by plane?

    A flight from Lambert-St Louis to Key West will travel around 1088.7 mi. 5h 14m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Key West Airport?

    Prices for flights from Lambert-St Louis Airport to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Key West Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Key West?

Best airlines flying from St. Louis to Key West

Compare and see reviews for airlines that fly from St. Louis to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $222Free CancellationRating
7.9
8,005 reviews
Search Delta flights
American AirlinesPriceFrom $227Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from St. Louis to Key West for you.

Can I find flights from St. Louis to Key West with flexible booking policies on momondo?

Flights from St. Louis to Key West with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Key West?

Once you have performed a search for St. Louis to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Key West right now. Can momondo alert me if prices change?

Yes. momondo can track prices for St. Louis to Key West flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Key West trip

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