Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from St. Louis to Key West from $182

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Key West departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from St. Louis to Key West

Cheap round-trip flights

American Airlines Logo
8:13 am - 2:55 pmSTL-EYW
5h 42m1 stop
American Airlines Logo
4:10 pm - 10:27 pmEYW-STL
7h 17m1 stop
$223American Airlines
Find Deal
Tue, Nov 11 - Tue, Nov 18
American Airlines Logo
8:13 am - 5:01 pmSTL-EYW
7h 48m2 stops
American Airlines Logo
6:33 pm - 11:07 pmEYW-STL
5h 34m1 stop
$228American Airlines
Find Deal
Tue, Nov 11 - Tue, Nov 18
American Airlines Logo
6:52 am - 4:57 pmSTL-EYW
9h 05m2 stops
American Airlines Logo
1:57 pm - 9:28 pmEYW-STL
8h 31m2 stops
$233American Airlines
Find Deal
Wed, Dec 3 - Sat, Dec 6
American Airlines Logo
8:13 am - 2:55 pmSTL-EYW
5h 42m1 stop
American Airlines Logo
6:33 pm - 11:07 pmEYW-STL
5h 34m1 stop
$241American Airlines
Find Deal
Tue, Nov 18 - Mon, Nov 24
American Airlines Logo
10:15 am - 7:23 pmSTL-EYW
8h 08m2 stops
American Airlines Logo
4:55 pm - 11:56 pmEYW-STL
8h 01m1 stop
$246American Airlines
Find Deal
Tue, Nov 18 - Mon, Nov 24
American Airlines Logo
7:01 am - 5:01 pmSTL-EYW
9h 00m2 stops
American Airlines Logo
7:00 am - 1:15 pmEYW-STL
7h 15m2 stops
$251American Airlines
Find Deal
Tue, Nov 18 - Mon, Nov 24
Delta Logo
6:00 am - 12:15 pmSTL-EYW
5h 15m1 stop
Delta Logo
6:00 pm - 11:39 pmEYW-STL
6h 39m1 stop
$256Delta
Find Deal
Wed, Dec 24 - Mon, Dec 29
Delta Logo
3:35 pm - 8:56 pmSTL-EYW
4h 21m1 stop
Delta Logo
6:20 pm - 11:39 pmEYW-STL
6h 19m1 stop
$259Delta
Find Deal
Tue, Dec 23 - Fri, Dec 26
Delta Logo
3:35 pm - 8:56 pmSTL-EYW
4h 21m1 stop
Delta Logo
6:00 pm - 11:39 pmEYW-STL
6h 39m1 stop
$274Delta
Find Deal
Tue, Dec 23 - Mon, Dec 29
Multiple Airlines Logo
7:45 pm - 11:05 amSTL-EYW
14h 20m2 stops
Multiple Airlines Logo
8:55 am - 10:20 amEYW-STL
26h 25m1 stop
$362Multiple Airlines
Find Deal
Mon, Nov 3 - Thu, Nov 13

Delta flights from St. Louis to Key West

Our best Delta deals on St. Louis to Key West flight tickets
Delta
Dec 24
STL6:00 amLambert-St Louis
5h 15m
1 stop
EYW12:15 pmKey West
Dec 29
EYW6:00 pmKey West
6h 39m
1 stop
STL11:39 pmLambert-St Louis
$256
Find similar
Delta
Dec 23
STL3:35 pmLambert-St Louis
4h 21m
1 stop
EYW8:56 pmKey West
Dec 26
EYW6:20 pmKey West
6h 19m
1 stop
STL11:39 pmLambert-St Louis
$259
Find similar
Delta
Dec 23
STL3:35 pmLambert-St Louis
4h 21m
1 stop
EYW8:56 pmKey West
Dec 29
EYW6:00 pmKey West
6h 39m
1 stop
STL11:39 pmLambert-St Louis
$274
Find similar

American Airlines flights from St. Louis to Key West

Our best American Airlines deals on St. Louis to Key West flight tickets
American Airlines
Nov 11
STL8:13 amLambert-St Louis
5h 42m
1 stop
EYW2:55 pmKey West
Nov 18
EYW4:10 pmKey West
7h 17m
1 stop
STL10:27 pmLambert-St Louis
$223
Find similar
American Airlines
Nov 11
STL8:13 amLambert-St Louis
7h 48m
2 stops
EYW5:01 pmKey West
Nov 18
EYW6:33 pmKey West
5h 34m
1 stop
STL11:07 pmLambert-St Louis
$228
Find similar
American Airlines
Dec 3
STL6:52 amLambert-St Louis
9h 05m
2 stops
EYW4:57 pmKey West
Dec 6
EYW1:57 pmKey West
8h 31m
2 stops
STL9:28 pmLambert-St Louis
$233
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from St. Louis to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 11/11

8:13 am-2:55 pm

1 stop5h 42m

Key West

Tue 11/18

4:10 pm-10:27 pm

1 stop7h 17m

$223

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 11/11

8:13 am-5:01 pm

2 stops7h 48m

Key West

Tue 11/18

6:33 pm-11:07 pm

1 stop5h 34m

$228

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 12/3

6:52 am-4:57 pm

2 stops9h 05m

Key West

Sat 12/6

1:57 pm-9:28 pm

2 stops8h 31m

$233

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 11/18

8:13 am-2:55 pm

1 stop5h 42m

Key West

Mon 11/24

6:33 pm-11:07 pm

1 stop5h 34m

$241

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 11/18

10:15 am-7:23 pm

2 stops8h 08m

Key West

Mon 11/24

4:55 pm-11:56 pm

1 stop8h 01m

$246

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 11/18

7:01 am-5:01 pm

2 stops9h 00m

Key West

Mon 11/24

7:00 am-1:15 pm

2 stops7h 15m

$251

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 12/24

6:00 am-12:15 pm

1 stop5h 15m

Key West

Mon 12/29

6:00 pm-11:39 pm

1 stop6h 39m

$256

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 12/23

3:35 pm-8:56 pm

1 stop4h 21m

Key West

Fri 12/26

6:20 pm-11:39 pm

1 stop6h 19m

$259

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 12/23

3:35 pm-8:56 pm

1 stop4h 21m

Key West

Mon 12/29

6:00 pm-11:39 pm

1 stop6h 39m

$274

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Mon 11/3

7:45 pm-11:05 am

2 stops14h 20m

Key West

Thu 11/13

8:55 am-10:20 am

1 stop26h 25m

$362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from St. Louis to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from St. Louis to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $353. If you are unable to visit Key West during the month of August, then departing from St. Louis during the month December is also very affordable. Most momondo users find prices during this month for around $378.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from St. Louis is on a Friday. momondo users have found tickets for Friday departures for as low as $376. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from St. Louis to Key West for around $557.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is at noon. momondo users have found flights departing from St. Louis to Key West at noon for as low as $394. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the afternoon, with an average ticket price of $470. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $427 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from St. Louis for as low as $334 on momondo.

When to book flights from St. Louis to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Key West (STL to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Key West

Direct flights

None
There are no direct flights from St. Louis to Key West. There are no popular flight routes from St. Louis to Key West.
Search flight deals

  • How far is Lambert-St Louis to Key West by plane?

    A flight from Lambert-St Louis to Key West will travel around 1088.7 mi. 4h 21m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Key West Airport?

    Prices for flights from Lambert-St Louis Airport to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Key West Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Key West?

Best airlines flying from St. Louis to Key West

Compare and see reviews for airlines that fly from St. Louis to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $217Free CancellationRating
7.9
7,957 reviews
Search Delta flights
United AirlinesPriceFrom $245Free CancellationRating
7.4
8,924 reviews
Search United Airlines flights
American AirlinesPriceFrom $246Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from St. Louis to Key West for you.

Can I find flights from St. Louis to Key West with flexible booking policies on momondo?

Flights from St. Louis to Key West with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Key West?

Once you have performed a search for St. Louis to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Key West right now. Can momondo alert me if prices change?

Yes. momondo can track prices for St. Louis to Key West flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 10/16
Thu 10/23
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States