Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from St. Louis to Key West from $187

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Key West departing on 7/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:34 pm - 10:19 am
STL
-
EYW
12h 45m
1 stop
Multiple Airlines Logo
12:01 pm - 9:40 am
EYW
-
STL
22h 39m
2 stops
$255Multiple Airlines
Sat, Oct 10 - Thu, Oct 15
Multiple Airlines Logo
6:17 pm - 12:34 pm
STL
-
EYW
41h 17m
2 stops
Multiple Airlines Logo
12:05 pm - 3:28 pm
EYW
-
STL
28h 23m
1 stop
$269Multiple Airlines
Sun, Aug 23 - Sun, Aug 30
Multiple Airlines Logo
10:35 am - 11:21 am
STL
-
EYW
23h 46m
2 stops
Multiple Airlines Logo
6:11 pm - 7:39 pm
EYW
-
STL
26h 28m
1 stop
$271Multiple Airlines
Sat, Sep 12 - Sun, Sep 20
Multiple Airlines Logo
10:35 am - 7:47 am
STL
-
EYW
20h 12m
2 stops
Multiple Airlines Logo
8:41 pm - 7:39 pm
EYW
-
STL
23h 58m
1 stop
$275Multiple Airlines
Wed, Oct 7 - Sun, Oct 11
Multiple Airlines Logo
5:02 pm - 11:27 am
STL
-
EYW
17h 25m
1 stop
Multiple Airlines Logo
11:04 am - 5:22 pm
EYW
-
STL
31h 18m
2 stops
$285Multiple Airlines
Thu, Aug 20 - Thu, Aug 27
Multiple Airlines Logo
10:35 am - 12:02 pm
STL
-
EYW
24h 27m
2 stops
Multiple Airlines Logo
8:29 am - 7:39 pm
EYW
-
STL
12h 10m
1 stop
$287Multiple Airlines
Tue, Oct 27 - Fri, Oct 30
Multiple Airlines Logo
8:34 pm - 7:44 am
STL
-
EYW
10h 10m
1 stop
Multiple Airlines Logo
8:41 pm - 9:40 am
EYW
-
STL
13h 59m
2 stops
$291Multiple Airlines
Thu, Oct 15 - Sun, Oct 18
Delta Logo
12:00 pm - 5:24 pm
STL
-
EYW
4h 24m
1 stop
Delta Logo
6:19 pm - 11:42 pm
EYW
-
STL
6h 23m
1 stop
$293Delta
Tue, Sep 22 - Sat, Sep 26
Multiple Airlines Logo
6:17 pm - 12:31 pm
STL
-
EYW
17h 14m
2 stops
Multiple Airlines Logo
12:05 pm - 3:28 pm
EYW
-
STL
28h 23m
1 stop
$294Multiple Airlines
Sun, Aug 23 - Thu, Aug 27
Multiple Airlines Logo
10:35 am - 11:21 am
STL
-
EYW
47h 46m
2 stops
Multiple Airlines Logo
10:59 am - 7:39 pm
EYW
-
STL
9h 40m
1 stop
$300Multiple Airlines
Fri, Oct 23 - Fri, Oct 30

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Delta flights from St. Louis to Key West

Our best Delta deals on St. Louis to Key West flight tickets
Delta
Aug 22
STL1:04 pmLambert-St Louis
5h 53m
1 stop
EYW7:57 pmKey West
Aug 26
EYW11:48 amKey West
5h 29m
1 stop
STL4:17 pmLambert-St Louis
$293
Delta
Oct 7
STL12:00 pmLambert-St Louis
6h 51m
1 stop
EYW7:51 pmKey West
Oct 11
EYW6:11 pmKey West
6h 37m
1 stop
STL11:48 pmLambert-St Louis
$390
Delta
Aug 16
STL6:00 amLambert-St Louis
6h 00m
1 stop
EYW1:00 pmKey West
Aug 22
EYW7:40 amKey West
5h 16m
1 stop
STL11:56 amLambert-St Louis
$395

American Airlines flights from St. Louis to Key West

Our best American Airlines deals on St. Louis to Key West flight tickets
American Airlines
Sep 22
STL10:21 amLambert-St Louis
6h 34m
1 stop
EYW5:55 pmKey West
Sep 26
EYW7:47 pmKey West
4h 59m
1 stop
STL11:46 pmLambert-St Louis
$343
American Airlines
Sep 11
STL6:53 amLambert-St Louis
6h 56m
1 stop
EYW2:49 pmKey West
Sep 15
EYW3:30 pmKey West
8h 12m
1 stop
STL10:42 pmLambert-St Louis
$362
American Airlines
Sep 22
STL8:43 amLambert-St Louis
5h 06m
1 stop
EYW2:49 pmKey West
Sep 26
EYW1:47 pmKey West
9h 55m
2 stops
STL10:42 pmLambert-St Louis
$374

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from St. Louis to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 10/10

8:34 pm-10:19 am

1 stop12h 45m

Key West

Thu 10/15

12:01 pm-9:40 am

2 stops22h 39m

$255

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 8/23

6:17 pm-12:34 pm

2 stops41h 17m

Key West

Sun 8/30

12:05 pm-3:28 pm

1 stop28h 23m

$269

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 9/12

10:35 am-11:21 am

2 stops23h 46m

Key West

Sun 9/20

6:11 pm-7:39 pm

1 stop26h 28m

$271

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 10/7

10:35 am-7:47 am

2 stops20h 12m

Key West

Sun 10/11

8:41 pm-7:39 pm

1 stop23h 58m

$275

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Thu 8/20

5:02 pm-11:27 am

1 stop17h 25m

Key West

Thu 8/27

11:04 am-5:22 pm

2 stops31h 18m

$285

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 10/27

10:35 am-12:02 pm

2 stops24h 27m

Key West

Fri 10/30

8:29 am-7:39 pm

1 stop12h 10m

$287

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Thu 10/15

8:34 pm-7:44 am

1 stop10h 10m

Key West

Sun 10/18

8:41 pm-9:40 am

2 stops13h 59m

$291
Quickest round-trip

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 9/22

12:00 pm-5:24 pm

1 stop4h 24m

Key West

Sat 9/26

6:19 pm-11:42 pm

1 stop6h 23m

$293

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 8/23

6:17 pm-12:31 pm

2 stops17h 14m

Key West

Thu 8/27

12:05 pm-3:28 pm

1 stop28h 23m

$294

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Fri 10/23

10:35 am-11:21 am

2 stops47h 46m

Key West

Fri 10/30

10:59 am-7:39 pm

1 stop9h 40m

$300

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from St. Louis to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and Key West?

What is the cheapest month to fly to Key West?

In general, December is the cheapest month to fly from St. Louis to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $283. If you are unable to visit Key West during the month of December, then departing from St. Louis during the month January is also very affordable. Most momondo users find prices during this month for around $308.

How far in advance should I book a flight from St. Louis to Key West?

You are more likely to see cheaper flights to Key West from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $446 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from St. Louis for as low as $330 on momondo.

When to book flights from St. Louis to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Key West (STL to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Key West

Fastest flight time

4h 20m

Direct flights

None
The fastest flight from St. Louis to Key West takes 4h 20m
There are no direct flights from St. Louis to Key West. There are no popular flight routes from St. Louis to Key West.
Search flight deals

Frequently asked questions about flying from St. Louis to Key West

  • How far is Lambert-St Louis to Key West by plane?

    A flight from Lambert-St Louis to Key West will travel around 1088.7 mi. 4h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Key West Airport?

    Prices for flights from Lambert-St Louis Airport to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Key West Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Key West?

Best airlines flying from St. Louis to Key West

Compare and see reviews for airlines that fly from St. Louis to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $222Free CancellationRating
7.1
11,806 reviews
Search American Airlines flights
DeltaPriceFrom $240Free CancellationRating
7.8
8,457 reviews
Search Delta flights
United AirlinesPriceFrom $262Free CancellationRating
7.4
9,976 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from St. Louis to Key West for you.

Can I find flights from St. Louis to Key West with flexible booking policies on momondo?

Flights from St. Louis to Key West with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Key West?

Once you have performed a search for St. Louis to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Key West right now. Can momondo alert me if prices change?

Yes. momondo can track prices for St. Louis to Key West flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 8/10
Mon 8/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States