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Cheap flights from St. Louis to Key West from $252

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Key West departing on 5/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from St. Louis to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:22 pm - 7:51 pm
STL
-
EYW
5h 29m
1 stop
Delta Logo
6:18 pm - 10:15 pm
EYW
-
STL
4h 57m
1 stop
$293Delta
Tue, Jul 7 - Tue, Jul 14
American Airlines Logo
9:08 am - 3:43 pm
STL
-
EYW
5h 35m
1 stop
American Airlines Logo
1:47 pm - 8:55 pm
EYW
-
STL
8h 08m
2 stops
$298American Airlines
Tue, Jul 7 - Tue, Jul 14
American Airlines Logo
6:55 am - 6:48 pm
STL
-
EYW
10h 53m
2 stops
American Airlines Logo
1:47 pm - 8:55 pm
EYW
-
STL
8h 08m
2 stops
$303American Airlines
Tue, Jul 7 - Tue, Jul 14
Multiple Airlines Logo
4:09 pm - 11:25 am
STL
-
EYW
18h 16m
1 stop
Multiple Airlines Logo
12:07 pm - 11:59 pm
EYW
-
STL
12h 52m
1 stop
$317Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
4:09 pm - 1:31 pm
STL
-
EYW
20h 22m
1 stop
Multiple Airlines Logo
3:27 pm - 11:59 pm
EYW
-
STL
9h 32m
1 stop
$336Multiple Airlines
Sat, Aug 8 - Fri, Aug 14
Multiple Airlines Logo
7:03 pm - 11:25 am
STL
-
EYW
15h 22m
2 stops
Multiple Airlines Logo
12:07 pm - 11:59 pm
EYW
-
STL
12h 52m
1 stop
$344Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
4:09 pm - 1:31 pm
STL
-
EYW
20h 22m
1 stop
Multiple Airlines Logo
12:07 pm - 8:57 am
EYW
-
STL
21h 50m
2 stops
$347Multiple Airlines
Sat, Aug 8 - Fri, Aug 14
Multiple Airlines Logo
8:08 pm - 11:25 am
STL
-
EYW
14h 17m
2 stops
Multiple Airlines Logo
12:07 pm - 11:59 pm
EYW
-
STL
12h 52m
1 stop
$350Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
United Airlines Logo
6:00 am - 3:07 pm
STL
-
EYW
8h 07m
1 stop
United Airlines Logo
3:55 pm - 9:30 pm
EYW
-
STL
6h 35m
1 stop
$352United Airlines
Fri, May 29 - Fri, Jun 5
American Airlines Logo
6:55 am - 4:11 pm
STL
-
EYW
8h 16m
2 stops
American Airlines Logo
4:41 pm - 12:16 am
EYW
-
STL
8h 35m
2 stops
$353American Airlines
Tue, Jul 7 - Tue, Jul 14

Delta flights from St. Louis to Key West

Our best Delta deals on St. Louis to Key West flight tickets
Delta
Jul 7
STL1:22 pmLambert-St Louis
5h 29m
1 stop
EYW7:51 pmKey West
Jul 14
EYW6:18 pmKey West
4h 57m
1 stop
STL10:15 pmLambert-St Louis
$293
Delta
Jun 30
STL1:39 pmLambert-St Louis
5h 14m
1 stop
EYW7:53 pmKey West
Jul 6
EYW6:24 pmKey West
4h 54m
1 stop
STL10:18 pmLambert-St Louis
$416
Delta
Aug 7
STL9:17 amLambert-St Louis
7h 03m
1 stop
EYW5:20 pmKey West
Aug 10
EYW1:57 pmKey West
4h 56m
1 stop
STL5:53 pmLambert-St Louis
$459

American Airlines flights from St. Louis to Key West

Our best American Airlines deals on St. Louis to Key West flight tickets
American Airlines
Jul 7
STL9:08 amLambert-St Louis
5h 35m
1 stop
EYW3:43 pmKey West
Jul 14
EYW1:47 pmKey West
8h 08m
2 stops
STL8:55 pmLambert-St Louis
$298
American Airlines
Jul 7
STL6:55 amLambert-St Louis
10h 53m
2 stops
EYW6:48 pmKey West
Jul 14
EYW1:47 pmKey West
8h 08m
2 stops
STL8:55 pmLambert-St Louis
$303
American Airlines
Jul 7
STL6:55 amLambert-St Louis
8h 16m
2 stops
EYW4:11 pmKey West
Jul 14
EYW4:41 pmKey West
8h 35m
2 stops
STL12:16 amLambert-St Louis
$353

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 25, 2026.
Use the filters below to find and compare flights from St. Louis to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 7/7

1:22 pm-7:51 pm

1 stop5h 29m

Key West

Tue 7/14

6:18 pm-10:15 pm

1 stop4h 57m

$293

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 7/7

9:08 am-3:43 pm

1 stop5h 35m

Key West

Tue 7/14

1:47 pm-8:55 pm

2 stops8h 08m

$298

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 7/7

6:55 am-6:48 pm

2 stops10h 53m

Key West

Tue 7/14

1:47 pm-8:55 pm

2 stops8h 08m

$303

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 8/12

4:09 pm-11:25 am

1 stop18h 16m

Key West

Mon 8/17

12:07 pm-11:59 pm

1 stop12h 52m

$317

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 8/8

4:09 pm-1:31 pm

1 stop20h 22m

Key West

Fri 8/14

3:27 pm-11:59 pm

1 stop9h 32m

$336

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 8/12

7:03 pm-11:25 am

2 stops15h 22m

Key West

Mon 8/17

12:07 pm-11:59 pm

1 stop12h 52m

$344

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 8/8

4:09 pm-1:31 pm

1 stop20h 22m

Key West

Fri 8/14

12:07 pm-8:57 am

2 stops21h 50m

$347

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 8/12

8:08 pm-11:25 am

2 stops14h 17m

Key West

Mon 8/17

12:07 pm-11:59 pm

1 stop12h 52m

$350

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Fri 5/29

6:00 am-3:07 pm

1 stop8h 07m

Key West

Fri 6/5

3:55 pm-9:30 pm

1 stop6h 35m

$352

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 7/7

6:55 am-4:11 pm

2 stops8h 16m

Key West

Tue 7/14

4:41 pm-12:16 am

2 stops8h 35m

$353

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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2

See travel insights to Key West from

How to get the cheapest flight ticket from St. Louis to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and Key West?

What is the cheapest month to fly to Key West?

In general, December is the cheapest month to fly from St. Louis to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $283. If you are unable to visit Key West during the month of December, then departing from St. Louis during the month January is also very affordable. Most momondo users find prices during this month for around $328.

How far in advance should I book a flight from St. Louis to Key West?

You are more likely to see cheaper flights to Key West from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $422 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from St. Louis for as low as $308 on momondo.

When to book flights from St. Louis to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Key West (STL to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Key West

Fastest flight time

4h 24m

Direct flights

None
The fastest flight from St. Louis to Key West takes 4h 24m
There are no direct flights from St. Louis to Key West. There are no popular flight routes from St. Louis to Key West.
Search flight deals

Frequently asked questions about flying from St. Louis to Key West

  • How far is Lambert-St Louis to Key West by plane?

    A flight from Lambert-St Louis to Key West will travel around 1088.7 mi. 4h 24m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Key West Airport?

    Prices for flights from Lambert-St Louis Airport to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Key West Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Key West?

Best airlines flying from St. Louis to Key West

Compare and see reviews for airlines that fly from St. Louis to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $222Free CancellationRating
7.1
11,629 reviews
Search American Airlines flights
DeltaPriceFrom $240Free CancellationRating
7.9
8,434 reviews
Search Delta flights
United AirlinesPriceFrom $262Free CancellationRating
7.4
9,748 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from St. Louis to Key West for you.

Can I find flights from St. Louis to Key West with flexible booking policies on momondo?

Flights from St. Louis to Key West with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Key West?

Once you have performed a search for St. Louis to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Key West right now. Can momondo alert me if prices change?

Yes. momondo can track prices for St. Louis to Key West flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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