Cheap flights from St. Louis to Columbus from $47

The cheapest month to fly to Columbus from St. Louis is in January. Flight prices, which tend to average around $332, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Columbus from St. Louis during June instead. Flights to Columbus in June, while not as cheap as those in January, still average around $350.

The cheapest day to depart from St. Louis to Columbus is on a Saturday when prices can be found for as low as $249. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $557. These prices are subject to change though, so be sure to set up a Price Alert for flights to Columbus.

Flying to Columbus from St. Louis in the evening is the least expensive time of day to depart. momondo users have found prices as low as $371 when looking at flights departing in the evening. Flights in the afternoon are often more expensive with an average ticket price of $659.

Fly from Lambert-St Louis to Columbus for the best Lambert-St Louis - Columbus flight prices

Delta is the most popular carrier operating from Lambert-St Louis to Columbus

Southwest, United Airlines and American Airlines are the top three most popular airlines that fly to Columbus from St. Louis according to our data. Southwest is the first choice among our users, with 66% of people opting to fly with this airline when traveling to Columbus. Keep in mind that there are 3 different airlines that fly to Columbus on a routine basis, so you have a few additional options to choose from.

1 flights are operational daily from St. Louis to Columbus as of September 2026. The most popular departure time for this route is 7:00AM, with 72% of flights per day taking off at noon.

As of September 2026, there are 11 flights per week flying from St. Louis to Columbus. The most common day of the week flights depart is Mon, with 27% of flights taking off on this day.