What airlines fly to Iowa?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Iowa from South Carolina according to our data. American Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 3 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Carolina to Iowa?

Frontier, American Airlines, and Delta are the most popular carriers operating from South Carolina to Iowa

How long is the flight from South Carolina to Iowa?

Flight times vary depending on what airport in South Carolina you fly out of and what airport in Iowa you fly into. For example, flying from Charleston to Des Moines takes 4h 47m on average. On the other hand, flying from Greenville to Des Moines takes 5h 12m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

How many flights depart from South Carolina to Iowa on average per week?

As of January 2026, 42 flights take off from South Carolina and land in Iowa each week. The most common flight departure day for this route is Mon, with 17% of weekly flights taking off on this day.

When did momondo last update prices for flights from South Carolina to Iowa?

Prices for flights from South Carolina to Iowa are updated daily.

How many operators does momondo search for flights from South Carolina to Iowa?

As of January 2026, there are 4 operators available to choose from for flights from South Carolina to Iowa.

How old do you have to be to fly from South Carolina to Iowa?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Iowa.

What documentation or ID do you need to fly to Iowa?

The necessary travel and health documents for your Iowa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$85 Cheap Flights from South Carolina to Iowa in 2026

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Find the cheapest flights from South Carolina to Iowa

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:13 pm - 6:32 pm

CLT

DSM

26h 19m1 stop

7:27 pm - 4:18 pm

DSM

CLT

19h 51m1 stop

$165Frontier

Sun, Feb 22 - Sun, Mar 1

6:35 pm - 8:25 am

CHS

CID

14h 50m1 stop

9:15 am - 5:36 pm

CID

CHS

7h 21m1 stop

$170Multiple Airlines

Thu, Jan 22 - Mon, Jan 26

11:30 am - 7:34 pm

GSP

DSM

9h 04m1 stop

5:24 am - 11:13 am

DSM

GSP

4h 49m1 stop

$237Delta

Tue, Feb 10 - Wed, Feb 25

6:00 am - 10:35 am

MYR

OMA

5h 35m1 stop

6:05 am - 12:05 pm

OMA

MYR

5h 00m1 stop

$251Delta

Tue, Mar 10 - Wed, Mar 18

10:15 am - 2:25 pm

CHS

OMA

5h 10m1 stop

8:15 am - 4:17 pm

OMA

CHS

7h 02m1 stop

$251United Airlines

Wed, Feb 4 - Wed, Feb 11

1:58 pm - 10:46 pm

MYR

OMA

9h 48m2 stops

5:17 pm - 11:55 pm

OMA

MYR

5h 38m1 stop

$256American Airlines

Tue, Mar 10 - Wed, Mar 18

1:18 pm - 10:56 pm

SAV

OMA

10h 38m2 stops

3:07 pm - 11:16 pm

OMA

SAV

7h 09m1 stop

$256American Airlines

Tue, Feb 3 - Tue, Feb 10

10:15 am - 8:14 pm

CHS

OMA

10h 59m2 stops

8:00 am - 2:02 pm

OMA

CHS

5h 02m1 stop

$256United Airlines

Wed, Feb 4 - Wed, Feb 11

11:15 am - 2:30 pm

SAV

OMA

4h 15m1 stop

10:40 am - 6:40 pm

OMA

SAV

7h 00m1 stop

$279Southwest

Wed, Feb 4 - Mon, Feb 9

4:00 pm - 9:40 pm

SAV

OMA

6h 40m2 stops

10:40 am - 6:40 pm

OMA

SAV

7h 00m1 stop

$284Southwest

Wed, Feb 4 - Mon, Feb 9

American Airlines flights from South Carolina to Iowa

Our best American Airlines deals on South Carolina to Iowa flight tickets

American Airlines

Feb 3

SAV1:18 pmSavannah/Hilton Head

10h 38m

2 stops

OMA10:56 pmOmaha Eppley Airfield

Feb 10

OMA3:07 pmOmaha Eppley Airfield

7h 09m

1 stop

SAV11:16 pmSavannah/Hilton Head

$256

American Airlines

Feb 3

CLT9:30 amCharlotte Douglas

7h 54m

1 stop

DSM4:24 pmDes Moines

Feb 10

DSM7:10 amDes Moines

10h 16m

1 stop

CLT6:26 pmCharlotte Douglas

$259

American Airlines

Feb 3

SAV1:18 pmSavannah/Hilton Head

11h 15m

2 stops

OMA11:33 pmOmaha Eppley Airfield

Feb 10

OMA12:03 pmOmaha Eppley Airfield

7h 57m

2 stops

SAV9:00 pmSavannah/Hilton Head

$262

Delta flights from South Carolina to Iowa

Our best Delta deals on South Carolina to Iowa flight tickets

Delta

Feb 10

GSP11:30 amGreenville

9h 04m

1 stop

DSM7:34 pmDes Moines

Feb 25

DSM5:24 amDes Moines

4h 49m

1 stop

GSP11:13 amGreenville

$237

Delta

Feb 3

SAV5:49 pmSavannah/Hilton Head

4h 27m

1 stop

OMA9:16 pmOmaha Eppley Airfield

Feb 10

OMA2:50 pmOmaha Eppley Airfield

4h 45m

1 stop

SAV8:35 pmSavannah/Hilton Head

$251

Delta

Feb 10

GSP6:50 amGreenville

4h 51m

1 stop

DSM10:41 amDes Moines

Mar 2

DSM5:15 pmDes Moines

5h 28m

1 stop

GSP11:43 pmGreenville

$263

Fly from

Fly to

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 2/22

5:13 pm-6:32 pm

1 stop26h 19m

Des Moines

Sun 3/1

7:27 pm-4:18 pm

1 stop19h 51m

$165

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Thu 1/22

6:35 pm-8:25 am

1 stop14h 50m

Cedar Rapids

Mon 1/26

9:15 am-5:36 pm

1 stop7h 21m

$170

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 2/10

11:30 am-7:34 pm

1 stop9h 04m

Des Moines

Wed 2/25

5:24 am-11:13 am

1 stop4h 49m

$237

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 3/10

6:00 am-10:35 am

1 stop5h 35m

Omaha Eppley Airfield

Wed 3/18

6:05 am-12:05 pm

1 stop5h 00m

$251

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

Wed 2/4

10:15 am-2:25 pm

1 stop5h 10m

Omaha Eppley Airfield

Wed 2/11

8:15 am-4:17 pm

1 stop7h 02m

$251

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 3/10

1:58 pm-10:46 pm

2 stops9h 48m

Omaha Eppley Airfield

Wed 3/18

5:17 pm-11:55 pm

1 stop5h 38m

$256

SavannahOmaha

SAV - OMA

SAVOMA

Savannah/Hilton Head

Tue 2/3

1:18 pm-10:56 pm

2 stops10h 38m

Omaha Eppley Airfield

Tue 2/10

3:07 pm-11:16 pm

1 stop7h 09m

$256

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

Wed 2/4

10:15 am-8:14 pm

2 stops10h 59m

Omaha Eppley Airfield

Wed 2/11

8:00 am-2:02 pm

1 stop5h 02m

$256

SavannahOmaha

SAV - OMA

SAVOMA

Savannah/Hilton Head

Wed 2/4

11:15 am-2:30 pm

1 stop4h 15m

Omaha Eppley Airfield

Mon 2/9

10:40 am-6:40 pm

1 stop7h 00m

$279

SavannahOmaha

SAV - OMA

SAVOMA

Savannah/Hilton Head

Wed 2/4

4:00 pm-9:40 pm

2 stops6h 40m

Omaha Eppley Airfield

Mon 2/9

10:40 am-6:40 pm

1 stop7h 00m

$284

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Iowa?

The month of May is another great option to travel to Iowa, with average flight prices from South Carolina averaging around $307.

Can stopping save me money on South Carolina to Iowa flights?

You could potentially save up to 65% on your flight if you consider stops on a South Carolina to Iowa flight.

Cheap South Carolina to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Iowa

Fastest flight time	2h 24m
Direct flights	Every day
Airports in Iowa	41 airports

The fastest flight from South Carolina to Iowa takes 2h 24m

Direct flights go from South Carolina to Iowa every day.

There are 41 airports in Iowa. From South Carolina there are direct flights to Omaha Eppley Airfield (OMA), Moline Quad-City (MLI), Cedar Rapids (CID), Des Moines (DSM).

Search flight deals

When did momondo last update prices for flights from South Carolina to Iowa?
Prices for flights from South Carolina to Iowa are updated daily.
How many operators does momondo search for flights from South Carolina to Iowa?
As of January 2026, there are 4 operators available to choose from for flights from South Carolina to Iowa.
How old do you have to be to fly from South Carolina to Iowa?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Iowa.
What documentation or ID do you need to fly to Iowa?
The necessary travel and health documents for your Iowa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Iowa

Compare and see reviews for airlines that fly from South Carolina to Iowa with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $204	Free Cancellation	Rating 7.2 11,094 reviews	Search American Airlines flights
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 8,025 reviews	Search Delta flights
United Airlines	PriceFrom $326	Free Cancellation	Rating 7.4 9,139 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Iowa?

Finding the right flight to Iowa from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Iowa quick and easy, saving you time and money.

Can I find flights from South Carolina to Iowa with flexible booking policies on momondo?

All flight searches from South Carolina to Iowa on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Iowa?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Iowa.

I’m not ready to book a flight from South Carolina to Iowa right now. Can momondo alert me if prices change?

Price alerts on flights to Iowa from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.