What is the cheapest airline that flies from South Carolina to Iowa?

Southwest, Delta, and United Airlines are the most popular carriers operating from South Carolina to Iowa

What airlines fly to Iowa?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Iowa from South Carolina according to our data. American Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 3 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to Iowa on average per week?

As of August 2026, 43 flights take off from South Carolina and land in Iowa each week. The most common flight departure day for this route is Mon, with 19% of weekly flights taking off on this day.

How long is the flight from South Carolina to Iowa?

Flight times vary depending on what airport in South Carolina you fly out of and what airport in Iowa you fly into. For example, flying from Myrtle Beach to Des Moines takes 4h 28m on average. On the other hand, flying from Greenville to Des Moines takes 4h 29m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

When did momondo last update prices for flights from South Carolina to Iowa?

Prices for flights from South Carolina to Iowa are updated daily.

How many operators does momondo search for flights from South Carolina to Iowa?

As of August 2026, there are 4 operators available to choose from for flights from South Carolina to Iowa.

How old do you have to be to fly from South Carolina to Iowa?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Iowa.

What documentation or ID do you need to fly to Iowa?

The necessary travel and health documents for your Iowa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$113 Cheap Flights from South Carolina to Iowa in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Iowa

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:00 am - 2:15 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

6h 15m1 stop Chicago O'Hare Intl

3:13 pm - 9:15 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

5h 02m1 stop Chicago O'Hare Intl

$235United Airlines

Wed, Sep 23 - Tue, Sep 29

11:30 am - 5:19 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

6h 49m1 stop Minneapolis St Paul

12:48 pm - 6:12 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

4h 24m1 stop Minneapolis St Paul

$235Delta

Tue, Dec 8 - Tue, Dec 15

9:00 am - 2:15 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

6h 15m1 stop Chicago O'Hare Intl

3:13 pm - 11:59 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

7h 46m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$240United Airlines

Wed, Sep 23 - Tue, Sep 29

7:46 pm - 7:46 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

25h 00m1 stop Denver Intl

8:41 pm - 6:51 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

21h 10m1 stop Denver Intl

$250Frontier

Sat, Oct 10 - Thu, Oct 15

7:40 am - 11:10 amCLT Charlotte Douglas-OMA Omaha Eppley Airfield

4h 30m1 stop Chicago Midway

4:20 pm - 9:35 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

4h 15m1 stop Chicago Midway

$257Southwest

Thu, Oct 29 - Mon, Nov 2

10:40 am - 5:20 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

7h 40m2 stops Lambert-St Louis Chicago Midway

4:20 pm - 9:35 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

4h 15m1 stop Chicago Midway

$263Southwest

Thu, Oct 29 - Mon, Nov 2

6:23 pm - 12:13 amGSP Greenville-OMA Omaha Eppley Airfield

6h 50m1 stop Chicago O'Hare Intl

3:16 pm - 9:54 pmOMA Omaha Eppley Airfield-GSP Greenville

5h 38m1 stop Chicago O'Hare Intl

$269American Airlines

Mon, Sep 28 - Tue, Sep 29

8:31 pm - 12:38 amGSP Greenville-OMA Omaha Eppley Airfield

5h 07m1 stop Charlotte Douglas

12:22 pm - 6:06 pmOMA Omaha Eppley Airfield-GSP Greenville

4h 44m1 stop Chicago O'Hare Intl

$269American Airlines

Thu, Oct 29 - Mon, Nov 2

7:02 am - 10:22 amCHS Charleston-MLI Moline Quad-City

4h 20m1 stop Atlanta Hartsfield-Jackson

11:08 am - 7:09 pmMLI Moline Quad-City-CHS Charleston

7h 01m1 stop Atlanta Hartsfield-Jackson

$271Delta

Sat, Oct 17 - Tue, Oct 20

9:40 pm - 9:34 amCLT Charlotte Douglas-DSM Des Moines

12h 54m1 stop Orlando

12:44 pm - 8:35 amDSM Des Moines-CLT Charlotte Douglas

18h 51m1 stop Orlando Sanford Intl

$275Multiple Airlines

Sun, Sep 13 - Wed, Sep 16

Cheap last minute flights

Enter your travel dates to find the best prices.

10:14 pm - 7:15 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

22h 01m1 stop Denver Intl

2:18 pm - 4:26 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

25h 08m1 stop Denver Intl

$266Frontier

Sat, Aug 15 - Sun, Aug 23

10:04 pm - 7:15 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

22h 11m1 stop Denver Intl

8:00 pm - 9:19 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

24h 19m1 stop Denver Intl

$310Frontier

Fri, Aug 14 - Sun, Aug 16

9:50 pm - 11:23 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 33mnonstop

6:14 am - 9:50 amOMA Omaha Eppley Airfield-CLT Charlotte Douglas

2h 36mnonstop

$323American Airlines

Sat, Aug 15 - Sat, Aug 22

9:50 pm - 11:23 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 33mnonstop

10:19 am - 4:24 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

5h 05m1 stop Chicago O'Hare Intl

$333American Airlines

Sat, Aug 15 - Sat, Aug 22

11:33 am - 4:57 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

6h 24m1 stop Minneapolis St Paul

12:10 pm - 8:27 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

7h 17m1 stop Atlanta Hartsfield-Jackson

$343Delta

Sat, Aug 15 - Sat, Aug 22

5:36 pm - 9:58 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

5h 22m1 stop Chicago O'Hare Intl

7:25 am - 1:56 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

5h 31m1 stop Chicago O'Hare Intl

$343United Airlines

Sat, Aug 15 - Sat, Aug 22

6:30 am - 9:30 amCLT Charlotte Douglas-OMA Omaha Eppley Airfield

4h 00m1 stop Nashville Intl

7:40 am - 6:20 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

9h 40m2 stops Denver Intl Nashville Intl

$348Southwest

Sat, Aug 15 - Sat, Aug 22

5:04 pm - 8:54 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

4h 50m1 stop Detroit Metropolitan Wayne County

11:11 am - 6:21 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

6h 10m1 stop Minneapolis St Paul

$369Delta

Sat, Aug 15 - Mon, Aug 24

6:30 am - 9:30 amCLT Charlotte Douglas-OMA Omaha Eppley Airfield

4h 00m1 stop Nashville Intl

12:30 pm - 6:10 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

4h 40m1 stop Chicago Midway

$369Southwest

Sat, Aug 15 - Sat, Aug 15

3:00 pm - 9:23 pmCLT Charlotte Douglas-DSM Des Moines

7h 23m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

11:32 am - 5:17 pmDSM Des Moines-CLT Charlotte Douglas

4h 45m1 stop Chicago O'Hare Intl

$480United Airlines

Sat, Aug 15 - Sat, Aug 22

Cheap direct flights

Enter your travel dates to find the best prices.

2:22 pm - 4:00 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 38mnonstop

6:21 am - 9:57 amOMA Omaha Eppley Airfield-CLT Charlotte Douglas

2h 36mnonstop

$281American Airlines

Sat, Sep 5 - Sun, Sep 6

2:22 pm - 4:00 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 38mnonstop

6:21 am - 9:57 amOMA Omaha Eppley Airfield-CLT Charlotte Douglas

2h 36mnonstop

$282American Airlines

Sat, Sep 5 - Sun, Sep 6

4:30 pm - 6:08 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 38mnonstop

6:14 am - 9:50 amOMA Omaha Eppley Airfield-CLT Charlotte Douglas

2h 36mnonstop

$302American Airlines

Sun, Sep 6 - Tue, Sep 8

10:25 pm - 12:17 amCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 52mnonstop

6:19 am - 10:01 amOMA Omaha Eppley Airfield-CLT Charlotte Douglas

2h 42mnonstop

$323American Airlines

Wed, Nov 25 - Tue, Dec 1

7:40 pm - 9:16 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 36mnonstop

6:15 am - 9:50 amOMA Omaha Eppley Airfield-CLT Charlotte Douglas

2h 35mnonstop

$323American Airlines

Tue, Sep 22 - Sat, Sep 26

10:05 pm - 11:38 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 33mnonstop

6:15 am - 9:50 amOMA Omaha Eppley Airfield-CLT Charlotte Douglas

2h 35mnonstop

$323American Airlines

Tue, Sep 8 - Tue, Sep 15

8:40 pm - 10:24 pmCLT Charlotte Douglas-OMA Omaha Eppley Airfield

2h 44mnonstop

12:57 pm - 4:25 pmOMA Omaha Eppley Airfield-CLT Charlotte Douglas

2h 28mnonstop

$323American Airlines

Tue, Dec 8 - Tue, Dec 15

6:27 pm - 7:48 pmCLT Charlotte Douglas-DSM Des Moines

2h 21mnonstop

1:14 pm - 4:34 pmDSM Des Moines-CLT Charlotte Douglas

2h 20mnonstop

$401American Airlines

Wed, Sep 30 - Tue, Oct 6

10:25 pm - 11:58 pmCLT Charlotte Douglas-DSM Des Moines

2h 33mnonstop

7:05 am - 10:27 amDSM Des Moines-CLT Charlotte Douglas

2h 22mnonstop

$401American Airlines

Sat, Oct 17 - Wed, Oct 21

8:55 am - 10:40 amCLT Charlotte Douglas-DSM Des Moines

2h 45mnonstop

11:22 am - 2:42 pmDSM Des Moines-CLT Charlotte Douglas

2h 20mnonstop

$401American Airlines

Sat, Oct 17 - Wed, Oct 21

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Southwest flights from South Carolina to Iowa

Our best Southwest deals on South Carolina to Iowa flight tickets

Southwest

Oct 29

CLT7:40 amCharlotte Douglas

4h 30m

1 stop

OMA11:10 amOmaha Eppley Airfield

Nov 2

OMA4:20 pmOmaha Eppley Airfield

4h 15m

1 stop

CLT9:35 pmCharlotte Douglas

$257

Southwest

Oct 29

CLT10:40 amCharlotte Douglas

7h 40m

2 stops

OMA5:20 pmOmaha Eppley Airfield

Nov 2

OMA4:20 pmOmaha Eppley Airfield

4h 15m

1 stop

CLT9:35 pmCharlotte Douglas

$263

Southwest

Sep 1

CLT6:35 pmCharlotte Douglas

4h 10m

1 stop

OMA9:45 pmOmaha Eppley Airfield

Sep 5

OMA12:50 pmOmaha Eppley Airfield

4h 35m

1 stop

CLT6:25 pmCharlotte Douglas

$273

Frontier flights from South Carolina to Iowa

Our best Frontier deals on South Carolina to Iowa flight tickets

Frontier

Sep 17

CLT7:54 pmCharlotte Douglas

22h 39m

1 stop

OMA5:33 pmOmaha Eppley Airfield

Sep 19

OMA7:29 pmOmaha Eppley Airfield

22h 30m

1 stop

CLT6:59 pmCharlotte Douglas

$250

Frontier

Oct 9

CLT7:46 pmCharlotte Douglas

25h 00m

1 stop

OMA7:46 pmOmaha Eppley Airfield

Oct 11

OMA8:41 pmOmaha Eppley Airfield

21h 10m

1 stop

CLT6:51 pmCharlotte Douglas

$266

Frontier

Aug 14

CLT10:04 pmCharlotte Douglas

22h 11m

1 stop

OMA7:15 pmOmaha Eppley Airfield

Aug 16

OMA8:00 pmOmaha Eppley Airfield

24h 19m

1 stop

CLT9:19 pmCharlotte Douglas

$310

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteOmaha

CLT Charlotte Douglas - OMA Omaha Eppley Airfield

CLTOMA

Charlotte Douglas

Wed 9/23

9:00 am-2:15 pm

1 stop6h 15m

Omaha Eppley Airfield

Tue 9/29

3:13 pm-9:15 pm

1 stop5h 02m

$235

CharlotteOmaha

CLT Charlotte Douglas - OMA Omaha Eppley Airfield

CLTOMA

Charlotte Douglas

Tue 12/8

11:30 am-5:19 pm

1 stop6h 49m

Omaha Eppley Airfield

Tue 12/15

12:48 pm-6:12 pm

1 stop4h 24m

$235

CharlotteOmaha

CLT Charlotte Douglas - OMA Omaha Eppley Airfield

CLTOMA

Charlotte Douglas

Wed 9/23

9:00 am-2:15 pm

1 stop6h 15m

Omaha Eppley Airfield

Tue 9/29

3:13 pm-11:59 pm

2 stops7h 46m

$240

CharlotteOmaha

CLT Charlotte Douglas - OMA Omaha Eppley Airfield

CLTOMA

Charlotte Douglas

Sat 10/10

7:46 pm-7:46 pm

1 stop25h 00m

Omaha Eppley Airfield

Thu 10/15

8:41 pm-6:51 pm

1 stop21h 10m

$250

Quickest round-trip

CharlotteOmaha

CLT Charlotte Douglas - OMA Omaha Eppley Airfield

CLTOMA

Charlotte Douglas

Thu 10/29

7:40 am-11:10 am

1 stop4h 30m

Omaha Eppley Airfield

Mon 11/2

4:20 pm-9:35 pm

1 stop4h 15m

$257

CharlotteOmaha

CLT Charlotte Douglas - OMA Omaha Eppley Airfield

CLTOMA

Charlotte Douglas

Thu 10/29

10:40 am-5:20 pm

2 stops7h 40m

Omaha Eppley Airfield

Mon 11/2

4:20 pm-9:35 pm

1 stop4h 15m

$263

GreenvilleOmaha

GSP Greenville - OMA Omaha Eppley Airfield

GSPOMA

Greenville

Mon 9/28

6:23 pm-12:13 am

1 stop6h 50m

Omaha Eppley Airfield

Tue 9/29

3:16 pm-9:54 pm

1 stop5h 38m

$269

GreenvilleOmaha

GSP Greenville - OMA Omaha Eppley Airfield

GSPOMA

Greenville

Thu 10/29

8:31 pm-12:38 am

1 stop5h 07m

Omaha Eppley Airfield

Mon 11/2

12:22 pm-6:06 pm

1 stop4h 44m

$269

CharlestonMoline

CHS Charleston - MLI Moline Quad-City

CHSMLI

Charleston

Sat 10/17

7:02 am-10:22 am

1 stop4h 20m

Moline Quad-City

Tue 10/20

11:08 am-7:09 pm

1 stop7h 01m

$271

CharlotteDes Moines

CLT Charlotte Douglas - DSM Des Moines

CLTDSM

Charlotte Douglas

Sun 9/13

9:40 pm-9:34 am

1 stop12h 54m

Des Moines

Wed 9/16

12:44 pm-8:35 am

1 stop18h 51m

$275

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Iowa?

The month of October is another great option to travel to Iowa, with average flight prices from South Carolina averaging around $376.

Can stopping save me money on South Carolina to Iowa flights?

You could potentially save up to 47% on your flight if you consider stops on a South Carolina to Iowa flight.

Cheap South Carolina to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Iowa

Fastest flight time	2h 14m
Direct flights	Every day
Airports in Iowa	41 airports

The fastest flight from South Carolina to Iowa takes 2h 14m

Direct flights go from South Carolina to Iowa every day.

There are 41 airports in Iowa. From South Carolina there are direct flights to Omaha Eppley Airfield (OMA), Cedar Rapids (CID), Des Moines (DSM).

Search flight deals

Frequently asked questions about flying from South Carolina to Iowa

When did momondo last update prices for flights from South Carolina to Iowa?
Prices for flights from South Carolina to Iowa are updated daily.
How many operators does momondo search for flights from South Carolina to Iowa?
As of August 2026, there are 4 operators available to choose from for flights from South Carolina to Iowa.
How old do you have to be to fly from South Carolina to Iowa?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Iowa.
What documentation or ID do you need to fly to Iowa?
The necessary travel and health documents for your Iowa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Iowa

Compare and see reviews for airlines that fly from South Carolina to Iowa with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $233	Free Cancellation	Rating 7.1 11,911 reviews	Search American Airlines flights
Delta	PriceFrom $250	Free Cancellation	Rating 7.8 8,505 reviews	Search Delta flights
United Airlines	PriceFrom $326	Free Cancellation	Rating 7.4 10,111 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Iowa?

Finding the right flight to Iowa from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Iowa quick and easy, saving you time and money.

Can I find flights from South Carolina to Iowa with flexible booking policies on momondo?

All flight searches from South Carolina to Iowa on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Iowa?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Iowa.

I’m not ready to book a flight from South Carolina to Iowa right now. Can momondo alert me if prices change?

Price alerts on flights to Iowa from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.