What is the cheapest airline that flies from South Carolina to Iowa?

American Airlines, Delta, and Frontier are the most popular carriers operating from South Carolina to Iowa

How many flights depart from South Carolina to Iowa on average per week?

As of August 2025, 36 flights take off from South Carolina and land in Iowa each week. The most common flight departure day for this route is Tue, with 22% of weekly flights taking off on this day.

How long is the flight from South Carolina to Iowa?

Flight times vary depending on what airport in South Carolina you fly out of and what airport in Iowa you fly into. For example, flying from Charleston to Des Moines takes 4h 28m on average. On the other hand, flying from Columbia to Des Moines takes 4h 33m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

When did momondo last update prices for flights from South Carolina to Iowa?

Prices for flights from South Carolina to Iowa are updated daily.

How many operators does momondo search for flights from South Carolina to Iowa?

As of August 2025, there are 4 operators available to choose from for flights from South Carolina to Iowa.

How old do you have to be to fly from South Carolina to Iowa?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Iowa.

What documentation or ID do you need to fly to Iowa?

The necessary travel and health documents for your Iowa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$109 Cheap Flights from South Carolina to Iowa in 2025

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Find the cheapest flights from South Carolina to Iowa

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

2:56 pm - 4:32 pmCLT-OMA

2h 36mnonstop

5:24 pm - 9:00 pmOMA-CLT

2h 36mnonstop

$217American Airlines

Find Deal

Wed, Sep 3 - Sat, Sep 6

9:52 pm - 1:32 pmCLT-DSM

16h 40m2 stops

5:49 pm - 4:31 pmDSM-CLT

21h 42m2 stops

$219

Find Deal

Thu, Sep 4 - Sun, Sep 7

5:20 pm - 7:50 pmCLT-OMA

27h 30m1 stop

7:40 pm - 4:25 pmOMA-CLT

19h 45m1 stop

$225Frontier

Find Deal

Thu, Sep 18 - Sun, Sep 21

6:45 am - 10:05 amCLT-DSM

4h 20m1 stop

5:56 pm - 11:03 pmDSM-CLT

4h 07m1 stop

$227Delta

Find Deal

Wed, Oct 29 - Wed, Oct 29

6:20 am - 10:13 amCLT-OMA

4h 53m1 stop

10:53 am - 4:28 pmOMA-CLT

4h 35m1 stop

$227Delta

Find Deal

Mon, Sep 1 - Thu, Sep 4

4:00 pm - 10:05 pmCLT-OMA

7h 05m1 stop

10:45 am - 4:00 pmOMA-CLT

4h 15m1 stop

$236Southwest

Find Deal

Mon, Sep 8 - Wed, Sep 10

6:40 am - 10:24 amCLT-OMA

4h 44m1 stop

3:18 pm - 9:37 pmOMA-CLT

5h 19m1 stop

$237United Airlines

Find Deal

Wed, Sep 3 - Sat, Sep 6

6:40 am - 10:24 amCLT-OMA

4h 44m1 stop

9:11 am - 9:37 pmOMA-CLT

11h 26m2 stops

$242United Airlines

Find Deal

Wed, Sep 3 - Sat, Sep 6

5:21 pm - 6:48 pmCLT-DSM

26h 27m1 stop

3:23 pm - 4:37 pmDSM-CLT

24h 14m1 stop

$247Frontier

Find Deal

Sun, Aug 17 - Thu, Aug 21

7:50 pm - 10:55 pmCLT-OMA

4h 05m1 stop

9:00 am - 6:15 pmOMA-CLT

8h 15m1 stop

$258Southwest

Find Deal

Thu, Aug 28 - Sun, Aug 31

American Airlines flights from South Carolina to Iowa

Our best American Airlines deals on South Carolina to Iowa flight tickets

American Airlines

Sep 3

CLT2:56 pmCharlotte Douglas

2h 36m

OMA4:32 pmOmaha Eppley Airfield

Sep 6

OMA5:24 pmOmaha Eppley Airfield

2h 36m

CLT9:00 pmCharlotte Douglas

$217

Find similar

American Airlines

Aug 28

CLT10:50 pmCharlotte Douglas

2h 38m

OMA12:28 amOmaha Eppley Airfield

Aug 31

OMA6:16 amOmaha Eppley Airfield

2h 35m

CLT9:51 amCharlotte Douglas

$239

Find similar

American Airlines

Aug 28

CLT10:50 pmCharlotte Douglas

2h 38m

OMA12:28 amOmaha Eppley Airfield

Aug 31

OMA6:19 amOmaha Eppley Airfield

4h 19m

1 stop

CLT11:38 amCharlotte Douglas

$249

Find similar

United Airlines flights from South Carolina to Iowa

Our best United Airlines deals on South Carolina to Iowa flight tickets

United Airlines

Sep 3

CLT6:40 amCharlotte Douglas

4h 44m

1 stop

OMA10:24 amOmaha Eppley Airfield

Sep 6

OMA3:18 pmOmaha Eppley Airfield

5h 19m

1 stop

CLT9:37 pmCharlotte Douglas

$237

Find similar

United Airlines

Sep 3

CLT6:40 amCharlotte Douglas

4h 44m

1 stop

OMA10:24 amOmaha Eppley Airfield

Sep 6

OMA9:11 amOmaha Eppley Airfield

11h 26m

2 stops

CLT9:37 pmCharlotte Douglas

$242

Find similar

United Airlines

Sep 10

CLT6:40 amCharlotte Douglas

4h 44m

1 stop

OMA10:24 amOmaha Eppley Airfield

Sep 13

OMA8:00 amOmaha Eppley Airfield

9h 53m

2 stops

CLT6:53 pmCharlotte Douglas

$299

Find similar

Fly from

Fly to

Route

Depart

Return

Price

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Wed 9/3

2:56 pm-4:32 pm

Nonstop2h 36m

Omaha Eppley Airfield

Sat 9/6

5:24 pm-9:00 pm

Nonstop2h 36m

$217

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 9/4

9:52 pm-1:32 pm

2 stops16h 40m

Des Moines

Sun 9/7

5:49 pm-4:31 pm

2 stops21h 42m

$219

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Thu 9/18

5:20 pm-7:50 pm

1 stop27h 30m

Omaha Eppley Airfield

Sun 9/21

7:40 pm-4:25 pm

1 stop19h 45m

$225

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 10/29

6:45 am-10:05 am

1 stop4h 20m

Des Moines

Wed 10/29

5:56 pm-11:03 pm

1 stop4h 07m

$227

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Mon 9/1

6:20 am-10:13 am

1 stop4h 53m

Omaha Eppley Airfield

Thu 9/4

10:53 am-4:28 pm

1 stop4h 35m

$227

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Mon 9/8

4:00 pm-10:05 pm

1 stop7h 05m

Omaha Eppley Airfield

Wed 9/10

10:45 am-4:00 pm

1 stop4h 15m

$236

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Wed 9/3

6:40 am-10:24 am

1 stop4h 44m

Omaha Eppley Airfield

Sat 9/6

3:18 pm-9:37 pm

1 stop5h 19m

$237

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Wed 9/3

6:40 am-10:24 am

1 stop4h 44m

Omaha Eppley Airfield

Sat 9/6

9:11 am-9:37 pm

2 stops11h 26m

$242

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 8/17

5:21 pm-6:48 pm

1 stop26h 27m

Des Moines

Thu 8/21

3:23 pm-4:37 pm

1 stop24h 14m

$247

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Thu 8/28

7:50 pm-10:55 pm

1 stop4h 05m

Omaha Eppley Airfield

Sun 8/31

9:00 am-6:15 pm

1 stop8h 15m

$258

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Iowa?

The month of April is another great option to travel to Iowa, with average flight prices from South Carolina averaging around $357.

What is the cheapest day to depart on your flight to Iowa?

The cheapest day to depart from South Carolina to Iowa is on a Wednesday when prices can be found for as low as $321. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $594. These prices are subject to change though, so be sure to set up a Price Alert for flights to Iowa.

What is the cheapest time of day to depart on your flight to Iowa?

Our most recent data shows that the best time of day to fly to Iowa is in the afternoon. Flights from South Carolina to Iowa during this time can be as low as $411. Try not to purchase tickets at noon because they tend to be around $485. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on South Carolina to Iowa flights?

You could potentially save up to 76% on your flight if you consider stops on a South Carolina to Iowa flight.

Cheap South Carolina to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Iowa

Best Price Found	$109
Fastest flight time	2h 09m
Direct flights	Every day
Airports in Iowa	4 airports

The best one-way flight to Iowa from South Carolina in the past 72 hours is $109. The best round-trip flight deal from South Carolina to Iowa found on momondo in the last 72 hours is $217.

The fastest flight from South Carolina to Iowa takes 2h 09m

Direct flights go from South Carolina to Iowa every day.

There are 4 airports near Iowa: Omaha Eppley Airfield (OMA), Moline Quad-City (MLI), Des Moines (DSM), Cedar Rapids (CID)

Search flight deals

When did momondo last update prices for flights from South Carolina to Iowa?
Prices for flights from South Carolina to Iowa are updated daily.
How many operators does momondo search for flights from South Carolina to Iowa?
As of August 2025, there are 4 operators available to choose from for flights from South Carolina to Iowa.
How old do you have to be to fly from South Carolina to Iowa?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Iowa.
What documentation or ID do you need to fly to Iowa?
The necessary travel and health documents for your Iowa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Iowa

Compare and see reviews for airlines that fly from South Carolina to Iowa with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $204	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights
Delta	PriceFrom $216	Free Cancellation	Rating 8.0 7,983 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Iowa?

Finding the right flight to Iowa from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Iowa quick and easy, saving you time and money.

Can I find flights from South Carolina to Iowa with flexible booking policies on momondo?

All flight searches from South Carolina to Iowa on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Iowa?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Iowa.

I’m not ready to book a flight from South Carolina to Iowa right now. Can momondo alert me if prices change?

Price alerts on flights to Iowa from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.