What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from South Carolina according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 4 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Carolina to Florida Keys?

Breeze Airways, Delta, and Allegiant Air are the most popular carriers operating from South Carolina to Florida Keys

How long is the flight from South Carolina to Florida Keys?

On average, it takes 16h 46m to fly from South Carolina to Florida Keys if you fly out of Myrtle Beach (the most popular airport in South Carolina) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Charleston and into Copenhagen, then the flight time is around 18h 21m.

How many flights depart from South Carolina to Florida Keys on average per week?

As of July 2026, there are 97 flights per week flying from South Carolina to Florida Keys. The most common day of the week flights depart is Tue, with 37% of flights taking off on this day.

When did momondo last update prices for flights from South Carolina to Florida Keys?

Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Florida Keys?

There are 7 operators available for flights from South Carolina to Florida Keys as of July 2026.

How old do you have to be to fly from South Carolina to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$57 Cheap Flights from South Carolina to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:58 pm - 4:13 pm

CLT

MIA

2h 15mnonstop

2:27 pm - 4:46 pm

MIA

CLT

2h 19mnonstop

$94Frontier

Fri, Aug 28 - Thu, Sep 3

1:58 pm - 4:13 pm

CLT

MIA

2h 15mnonstop

2:27 pm - 4:46 pm

MIA

CLT

2h 19mnonstop

$96Frontier

Thu, Aug 27 - Fri, Sep 4

6:00 am - 9:24 am

CHS

EYW

3h 24m

1 stop

10:04 am - 1:24 pm

EYW

CHS

3h 20m

1 stop

$121Breeze Airways

Sat, Sep 12 - Sat, Sep 19

6:00 am - 9:24 am

CHS

EYW

3h 24m

1 stop

12:59 pm - 1:24 pm

EYW

CHS

24h 25m

1 stop

$141Breeze Airways

Sat, Sep 19 - Fri, Sep 25

6:19 pm - 12:53 am

CHS

MIA

6h 34m

1 stop

8:10 am - 1:13 pm

MIA

CHS

5h 03m

1 stop

$227Delta

Sat, Oct 31 - Sat, Nov 7

6:08 pm - 1:07 am

CAE

MIA

6h 59m

1 stop

7:00 am - 11:09 am

MIA

CAE

4h 09m

1 stop

$227Delta

Fri, Aug 28 - Sat, Aug 29

8:41 pm - 11:05 pm

MYR

MIA

26h 24m

2 stops

9:17 pm - 7:35 pm

MIA

MYR

22h 18m

1 stop

$238Multiple Airlines

Fri, Aug 21 - Sat, Aug 29

9:30 pm - 11:05 pm

MYR

MIA

25h 35m

2 stops

9:17 pm - 7:35 pm

MIA

MYR

22h 18m

1 stop

$240Multiple Airlines

Mon, Aug 3 - Sat, Aug 29

8:13 pm - 9:58 pm

CHS

MIA

1h 45mnonstop

5:00 pm - 6:51 pm

MIA

CHS

1h 51mnonstop

$247American Airlines

Fri, Jul 24 - Tue, Jul 28

6:00 am - 7:40 am

CHS

MIA

1h 40mnonstop

10:15 pm - 11:59 pm

MIA

CHS

1h 44mnonstop

$248American Airlines

Mon, Aug 10 - Mon, Aug 17

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Delta flights from South Carolina to Florida Keys

Our best Delta deals on South Carolina to Florida Keys flight tickets

Delta

Oct 31

CHS6:19 pmCharleston

6h 34m

1 stop

MIA12:53 amMiami

Nov 7

MIA8:10 amMiami

5h 03m

1 stop

CHS1:13 pmCharleston

$227

Delta

Sep 4

CHS6:45 pmCharleston

6h 02m

1 stop

MIA12:47 amMiami

Sep 8

MIA10:30 amMiami

6h 41m

1 stop

CHS5:11 pmCharleston

$267

Delta

Aug 6

CAE3:50 pmColumbia Metropolitan

7h 01m

1 stop

MIA10:51 pmMiami

Aug 9

MIA7:00 amMiami

4h 09m

1 stop

CAE11:09 amColumbia Metropolitan

$268

American Airlines flights from South Carolina to Florida Keys

Our best American Airlines deals on South Carolina to Florida Keys flight tickets

American Airlines

Jul 24

CHS8:13 pmCharleston

1h 45m

MIA9:58 pmMiami

Jul 28

MIA5:00 pmMiami

1h 51m

CHS6:51 pmCharleston

$247

American Airlines

Aug 10

CHS6:00 amCharleston

1h 40m

MIA7:40 amMiami

Aug 17

MIA10:15 pmMiami

1h 44m

CHS11:59 pmCharleston

$248

American Airlines

Aug 13

CHS6:00 amCharleston

1h 40m

MIA7:40 amMiami

Aug 20

MIA10:15 pmMiami

1h 44m

CHS11:59 pmCharleston

$249

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Fri 8/28

1:58 pm-4:13 pm

Nonstop2h 15m

Miami

Thu 9/3

2:27 pm-4:46 pm

Nonstop2h 19m

$94

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Thu 8/27

1:58 pm-4:13 pm

Nonstop2h 15m

Miami

Fri 9/4

2:27 pm-4:46 pm

Nonstop2h 19m

$96

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sat 9/12

6:00 am-9:24 am

1 stop3h 24m

Key West

Sat 9/19

10:04 am-1:24 pm

1 stop3h 20m

$121

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sat 9/19

6:00 am-9:24 am

1 stop3h 24m

Key West

Fri 9/25

12:59 pm-1:24 pm

1 stop24h 25m

$141

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 10/31

6:19 pm-12:53 am

1 stop6h 34m

Miami

Sat 11/7

8:10 am-1:13 pm

1 stop5h 03m

$227

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Fri 8/28

6:08 pm-1:07 am

1 stop6h 59m

Miami

Sat 8/29

7:00 am-11:09 am

1 stop4h 09m

$227

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 8/21

8:41 pm-11:05 pm

2 stops26h 24m

Miami

Sat 8/29

9:17 pm-7:35 pm

1 stop22h 18m

$238

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 8/3

9:30 pm-11:05 pm

2 stops25h 35m

Miami

Sat 8/29

9:17 pm-7:35 pm

1 stop22h 18m

$240

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 7/24

8:13 pm-9:58 pm

Nonstop1h 45m

Miami

Tue 7/28

5:00 pm-6:51 pm

Nonstop1h 51m

$247

Quickest round-trip

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 8/10

6:00 am-7:40 am

Nonstop1h 40m

Miami

Mon 8/17

10:15 pm-11:59 pm

Nonstop1h 44m

$248

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $65.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Friday when prices can be found for as low as $509. The most expensive day to fly to Florida Keys is Monday, with ticket prices averaging around $579.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from South Carolina to Florida Keys in the afternoon for as low as $287. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $544.

How far in advance should I book a flight from South Carolina to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $315 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from South Carolina for as low as $256 on momondo.

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time	1h 33m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from South Carolina to Florida Keys takes 1h 33m

Direct flights go from South Carolina to Florida Keys every day.

There are 3 airports in Florida Keys. From South Carolina there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from South Carolina to Florida Keys

When did momondo last update prices for flights from South Carolina to Florida Keys?
Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Florida Keys?
There are 7 operators available for flights from South Carolina to Florida Keys as of July 2026.
How old do you have to be to fly from South Carolina to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Florida Keys?
Based on momondo bookings for flights between South Carolina and Florida Keys, the leading plane model is Airbus A220-300, making up 21.66% of the total bookings. Other popular models include Canadair (Bombardier) Regional Jet 900 with 12.30%, Airbus A320-100/200 with 10.49%, and Embraer 175 with 9.76%.

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $65	Free Cancellation	Rating 7.3 689 reviews	Search Allegiant Air flights
Breeze Airways	PriceFrom $106	Free Cancellation	Rating 8.2 294 reviews	Search Breeze Airways flights
Delta	PriceFrom $125	Free Cancellation	Rating 7.8 8,451 reviews	Search Delta flights
American Airlines	PriceFrom $263	Free Cancellation	Rating 7.1 11,764 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from South Carolina.

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

All flight searches from South Carolina to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Florida Keys.

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.