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Cheap flights from South Carolina to Florida Keys from $48

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Florida Keys departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Florida Keys

Cheap round-trip flights

Frontier Logo
7:29 pm - 9:41 pmCLT-MIA
2h 12mnonstop
Frontier Logo
4:21 pm - 6:34 pmMIA-CLT
2h 13mnonstop
$79Frontier
Find Deal
Mon, Oct 13 - Mon, Oct 20
Frontier Logo
7:29 pm - 9:41 pmCLT-MIA
2h 12mnonstop
Frontier Logo
4:21 pm - 6:34 pmMIA-CLT
2h 13mnonstop
$80Frontier
Find Deal
Mon, Oct 13 - Mon, Oct 20
Spirit Airlines Logo
1:49 pm - 3:53 pmCLT-MIA
2h 04mnonstop
Spirit Airlines Logo
10:24 am - 12:39 pmMIA-CLT
2h 15mnonstop
$84Spirit Airlines
Find Deal
Sun, Oct 12 - Sat, Oct 18
Spirit Airlines Logo
1:49 pm - 3:53 pmCLT-MIA
2h 04mnonstop
Spirit Airlines Logo
10:24 am - 12:39 pmMIA-CLT
2h 15mnonstop
$86Spirit Airlines
Find Deal
Sat, Oct 18 - Sat, Oct 25
Multiple Airlines Logo
7:01 pm - 9:13 pmCLT-MIA
2h 12mnonstop
Multiple Airlines Logo
10:24 am - 12:39 pmMIA-CLT
2h 15mnonstop
$113Multiple Airlines
Find Deal
Fri, Oct 10 - Sun, Oct 12
Multiple Airlines Logo
10:20 pm - 12:42 amCLT-MIA
2h 22mnonstop
Multiple Airlines Logo
10:24 am - 12:39 pmMIA-CLT
2h 15mnonstop
$116Multiple Airlines
Find Deal
Mon, Oct 6 - Thu, Oct 9
American Airlines Logo
7:57 pm - 9:39 pmCHS-MIA
1h 42mnonstop
American Airlines Logo
10:19 pm - 12:03 amMIA-CHS
1h 44mnonstop
$128American Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
American Airlines Logo
7:57 pm - 9:39 pmCHS-MIA
1h 42mnonstop
American Airlines Logo
10:19 pm - 12:03 amMIA-CHS
1h 44mnonstop
$133American Airlines
Find Deal
Sat, Nov 22 - Wed, Nov 26
Delta Logo
5:10 pm - 12:25 amSAV-MIA
7h 15m1 stop
Delta Logo
8:05 am - 1:34 pmMIA-SAV
5h 29m1 stop
$159Delta
Find Deal
Sat, Jan 24 - Wed, Feb 11
Delta Logo
6:55 pm - 12:29 amCHS-MIA
5h 34m1 stop
Delta Logo
6:00 am - 10:21 amMIA-CHS
4h 21m1 stop
$177Delta
Find Deal
Sat, Oct 11 - Sat, Oct 18

Frontier flights from South Carolina to Florida Keys

Our best Frontier deals on South Carolina to Florida Keys flight tickets
Frontier
Oct 13
CLT7:29 pmCharlotte Douglas
2h 12m
MIA9:41 pmMiami
Oct 20
MIA4:21 pmMiami
2h 13m
CLT6:34 pmCharlotte Douglas
$79
Find similar
Frontier
Oct 13
CLT7:29 pmCharlotte Douglas
2h 12m
MIA9:41 pmMiami
Oct 20
MIA4:21 pmMiami
2h 13m
CLT6:34 pmCharlotte Douglas
$80
Find similar
Frontier
Oct 10
CLT7:01 pmCharlotte Douglas
2h 12m
MIA9:13 pmMiami
Oct 13
MIA4:21 pmMiami
2h 13m
CLT6:34 pmCharlotte Douglas
$81
Find similar

Spirit Airlines flights from South Carolina to Florida Keys

Our best Spirit Airlines deals on South Carolina to Florida Keys flight tickets
Spirit Airlines
Oct 12
CLT1:49 pmCharlotte Douglas
2h 04m
MIA3:53 pmMiami
Oct 18
MIA10:24 amMiami
2h 15m
CLT12:39 pmCharlotte Douglas
$84
Find similar
Spirit Airlines
Oct 18
CLT1:49 pmCharlotte Douglas
2h 04m
MIA3:53 pmMiami
Oct 25
MIA10:24 amMiami
2h 15m
CLT12:39 pmCharlotte Douglas
$86
Find similar
Spirit Airlines
Oct 12
CLT1:49 pmCharlotte Douglas
2h 04m
MIA3:53 pmMiami
Oct 13
MIA10:24 amMiami
2h 15m
CLT12:39 pmCharlotte Douglas
$90
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 21, 2025.
Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Mon 10/13

7:29 pm-9:41 pm

Nonstop2h 12m

Miami

Mon 10/20

4:21 pm-6:34 pm

Nonstop2h 13m

$79

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Mon 10/13

7:29 pm-9:41 pm

Nonstop2h 12m

Miami

Mon 10/20

4:21 pm-6:34 pm

Nonstop2h 13m

$80

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 10/12

1:49 pm-3:53 pm

Nonstop2h 04m

Miami

Sat 10/18

10:24 am-12:39 pm

Nonstop2h 15m

$84

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sat 10/18

1:49 pm-3:53 pm

Nonstop2h 04m

Miami

Sat 10/25

10:24 am-12:39 pm

Nonstop2h 15m

$86

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Fri 10/10

7:01 pm-9:13 pm

Nonstop2h 12m

Miami

Sun 10/12

10:24 am-12:39 pm

Nonstop2h 15m

$113

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Mon 10/6

10:20 pm-12:42 am

Nonstop2h 22m

Miami

Thu 10/9

10:24 am-12:39 pm

Nonstop2h 15m

$116

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 11/21

7:57 pm-9:39 pm

Nonstop1h 42m

Miami

Mon 11/24

10:19 pm-12:03 am

Nonstop1h 44m

$128

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 11/22

7:57 pm-9:39 pm

Nonstop1h 42m

Miami

Wed 11/26

10:19 pm-12:03 am

Nonstop1h 44m

$133

SavannahMiami

SAV - MIA

SAVMIA

Savannah/Hilton Head

Sat 1/24

5:10 pm-12:25 am

1 stop7h 15m

Miami

Wed 2/11

8:05 am-1:34 pm

1 stop5h 29m

$159

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 10/11

6:55 pm-12:29 am

1 stop5h 34m

Miami

Sat 10/18

6:00 am-10:21 am

1 stop4h 21m

$177

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida Keys from

How to get the cheapest flight ticket from South Carolina to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $269.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Wednesday when prices can be found for as low as $481. The most expensive day to fly to Florida Keys is Saturday, with ticket prices averaging around $587.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from South Carolina to Florida Keys in the evening for as low as $366. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the afternoon are often more expensive with an average ticket price of $677.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $295 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from South Carolina for as low as $243 on momondo.

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time

1h 27m

Direct flights

Every day

Airports in Florida Keys

1 airport
The fastest flight from South Carolina to Florida Keys takes 1h 27m
Direct flights go from South Carolina to Florida Keys every day.
There is 1 airport near Florida Keys: Miami (MIA)
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Florida Keys?

    Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Florida Keys?

  • How old do you have to be to fly from South Carolina to Florida Keys?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Florida Keys?

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
7,966 reviews
Search Delta flights
American AirlinesPriceFrom $253Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from South Carolina.

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

All flight searches from South Carolina to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Florida Keys.

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Florida Keys trip

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