How many flights depart from South Carolina to Florida Keys on average per week?

As of March 2026, there are 155 flights per week flying from South Carolina to Florida Keys. The most common day of the week flights depart is Sat, with 26% of flights taking off on this day.

What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from South Carolina according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How long is the flight from South Carolina to Florida Keys?

On average, it takes 12h 39m to fly from South Carolina to Florida Keys if you fly out of Charleston (the most popular airport in South Carolina) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Greenville and into Copenhagen, then the flight time is around 13h 55m.

What is the cheapest airline that flies from South Carolina to Florida Keys?

Spirit Airlines, Frontier, and Breeze Airways are the most popular carriers operating from South Carolina to Florida Keys

When did momondo last update prices for flights from South Carolina to Florida Keys?

Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Florida Keys?

There are 8 operators available for flights from South Carolina to Florida Keys as of March 2026.

How old do you have to be to fly from South Carolina to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$39 Cheap Flights from South Carolina to Florida Keys in 2026

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Find the cheapest flights from South Carolina to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:33 pm - 8:46 pm

CLT

MIA

2h 13mnonstop

9:34 am - 11:45 am

MIA

CLT

2h 11mnonstop

$82Multiple Airlines

Fri, May 15 - Mon, May 18

7:00 am - 9:02 am

CLT

MIA

2h 02mnonstop

9:34 am - 11:45 am

MIA

CLT

2h 11mnonstop

$83Spirit Airlines

Sun, Apr 12 - Fri, Apr 17

8:42 pm - 10:59 pm

CLT

MIA

2h 17mnonstop

11:17 am - 1:43 pm

MIA

CLT

2h 26mnonstop

$88Frontier

Fri, Apr 10 - Fri, Apr 24

2:28 pm - 4:45 pm

CLT

MIA

2h 17mnonstop

2:59 pm - 5:13 pm

MIA

CLT

2h 14mnonstop

$89Frontier

Fri, May 1 - Fri, May 8

5:16 pm - 10:21 am

CHS

EYW

17h 05m

1 stop

4:22 pm - 7:59 pm

EYW

CHS

3h 37m

1 stop

$151Breeze Airways

Sat, Apr 25 - Thu, Apr 30

5:16 pm - 10:21 am

CHS

EYW

17h 05m

1 stop

4:22 pm - 7:59 pm

EYW

CHS

3h 37m

1 stop

$152Breeze Airways

Sat, Apr 25 - Thu, Apr 30

1:59 pm - 8:48 pm

CAE

MIA

6h 49m

1 stop

8:05 am - 1:14 pm

MIA

CAE

5h 09m

1 stop

$197Delta

Tue, Apr 14 - Wed, Apr 22

6:40 am - 12:40 pm

CHS

MIA

6h 00m

1 stop

12:35 pm - 8:25 pm

MIA

CHS

7h 50m

1 stop

$198Southwest

Tue, May 5 - Tue, May 12

7:40 am - 2:15 pm

CHS

MIA

6h 35m

1 stop

7:20 am - 5:40 pm

MIA

CHS

10h 20m

2 stops

$204Southwest

Tue, May 5 - Tue, May 12

5:47 pm - 10:48 pm

CAE

MIA

5h 01m

1 stop

6:00 am - 11:29 am

MIA

CAE

5h 29m

1 stop

$266Delta

Sun, Apr 26 - Sat, May 2

American Airlines flights from South Carolina to Florida Keys

Our best American Airlines deals on South Carolina to Florida Keys flight tickets

American Airlines

Apr 28

CHS6:00 amCharleston

1h 40m

MIA7:40 amMiami

Apr 28

MIA8:49 amMiami

7h 44m

1 stop

CHS4:33 pmCharleston

$213

American Airlines

May 6

SAV6:00 amSavannah/Hilton Head

1h 32m

MIA7:32 amMiami

May 6

MIA9:58 amMiami

11h 01m

1 stop

SAV8:59 pmSavannah/Hilton Head

$245

American Airlines

Apr 21

CHS8:09 pmCharleston

1h 41m

MIA9:50 pmMiami

Apr 28

MIA8:45 amMiami

1h 49m

CHS10:34 amCharleston

$279

United Airlines flights from South Carolina to Florida Keys

Our best United Airlines deals on South Carolina to Florida Keys flight tickets

United Airlines

Apr 22

CHS10:00 amCharleston

6h 16m

1 stop

MIA4:16 pmMiami

Apr 29

MIA6:00 pmMiami

5h 59m

1 stop

CHS11:59 pmCharleston

$297

United Airlines

Apr 1

GSP6:30 amGreenville

8h 35m

1 stop

MIA3:05 pmMiami

Apr 9

MIA8:55 amMiami

7h 59m

1 stop

GSP4:54 pmGreenville

$480

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Fri 5/15

6:33 pm-8:46 pm

Nonstop2h 13m

Miami

Mon 5/18

9:34 am-11:45 am

Nonstop2h 11m

$82

Quickest round-trip

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 4/12

7:00 am-9:02 am

Nonstop2h 02m

Miami

Fri 4/17

9:34 am-11:45 am

Nonstop2h 11m

$83

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Fri 4/10

8:42 pm-10:59 pm

Nonstop2h 17m

Miami

Fri 4/24

11:17 am-1:43 pm

Nonstop2h 26m

$88

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Fri 5/1

2:28 pm-4:45 pm

Nonstop2h 17m

Miami

Fri 5/8

2:59 pm-5:13 pm

Nonstop2h 14m

$89

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sat 4/25

5:16 pm-10:21 am

1 stop17h 05m

Key West

Thu 4/30

4:22 pm-7:59 pm

1 stop3h 37m

$151

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sat 4/25

5:16 pm-10:21 am

1 stop17h 05m

Key West

Thu 4/30

4:22 pm-7:59 pm

1 stop3h 37m

$152

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Tue 4/14

1:59 pm-8:48 pm

1 stop6h 49m

Miami

Wed 4/22

8:05 am-1:14 pm

1 stop5h 09m

$197

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 5/5

6:40 am-12:40 pm

1 stop6h 00m

Miami

Tue 5/12

12:35 pm-8:25 pm

1 stop7h 50m

$198

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 5/5

7:40 am-2:15 pm

1 stop6h 35m

Miami

Tue 5/12

7:20 am-5:40 pm

2 stops10h 20m

$204

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Sun 4/26

5:47 pm-10:48 pm

1 stop5h 01m

Miami

Sat 5/2

6:00 am-11:29 am

1 stop5h 29m

$266

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $263.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Friday when prices can be found for as low as $479. The most expensive day to fly to Florida Keys is Monday, with ticket prices averaging around $553.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from South Carolina to Florida Keys in the afternoon for as low as $287. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $521.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $294 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from South Carolina for as low as $235 on momondo.

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time	1h 32m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from South Carolina to Florida Keys takes 1h 32m

Direct flights go from South Carolina to Florida Keys every day.

There are 3 airports in Florida Keys. From South Carolina there are direct flights to Miami (MIA).

Search flight deals

When did momondo last update prices for flights from South Carolina to Florida Keys?
Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Florida Keys?
There are 8 operators available for flights from South Carolina to Florida Keys as of March 2026.
How old do you have to be to fly from South Carolina to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Florida Keys?
Based on momondo bookings for flights between South Carolina and Florida Keys, the leading plane model is Airbus A220-300, making up 17.60% of the total bookings. Other popular models include Embraer 175 with 12.25%, Canadair (Bombardier) Regional Jet 900 with 10.24%, and Airbus A320-100/200 with 10.22%.

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $110	Free Cancellation	Rating 8.1 273 reviews	Search Breeze Airways flights
Delta	PriceFrom $125	Free Cancellation	Rating 7.9 8,341 reviews	Search Delta flights
American Airlines	PriceFrom $253	Free Cancellation	Rating 7.1 11,507 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from South Carolina.

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

All flight searches from South Carolina to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Florida Keys.

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.