How long is the flight from South Carolina to Florida Keys?

On average, it takes 5h 40m to fly from South Carolina to Florida Keys if you fly out of Greenville (the most popular airport in South Carolina) and into Los Angeles (the most popular airport in Florida Keys). If you’re flying out of Charleston and into Los Angeles, then the flight time is around 5h 45m.

What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from South Carolina according to our data. American Airlines is the first choice among our users, with 70% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to Florida Keys on average per week?

As of November 2025, there are 285 flights per week flying from South Carolina to Florida Keys. The most common day of the week flights depart is Thu, with 17% of flights taking off on this day.

What is the cheapest airline that flies from South Carolina to Florida Keys?

Frontier, American Airlines, and Spirit Airlines are the most popular carriers operating from South Carolina to Florida Keys

When did momondo last update prices for flights from South Carolina to Florida Keys?

Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Florida Keys?

There are 9 operators available for flights from South Carolina to Florida Keys as of November 2025.

How old do you have to be to fly from South Carolina to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$44 Cheap Flights from South Carolina to Florida Keys in 2025/26

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Cheap round-trip flights

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10:42 pm - 12:54 amCLT-MIA

2h 12mnonstop

7:00 am - 9:18 amMIA-CLT

2h 18mnonstop

$90Frontier

Find Deal

Thu, Nov 13 - Fri, Nov 28

10:42 pm - 12:54 amCLT-MIA

2h 12mnonstop

5:45 am - 7:47 amMIA-CLT

2h 02mnonstop

$91Multiple Airlines

Find Deal

Fri, Nov 14 - Sun, Nov 16

10:42 pm - 12:54 amCLT-MIA

2h 12mnonstop

7:00 am - 9:18 amMIA-CLT

2h 18mnonstop

$92Frontier

Find Deal

Sun, Nov 16 - Fri, Nov 21

9:38 pm - 11:51 pmCLT-MIA

2h 13mnonstop

6:46 am - 8:49 amMIA-CLT

2h 03mnonstop

$93Spirit Airlines

Find Deal

Sun, Nov 16 - Sun, Nov 23

10:42 pm - 12:54 amCLT-MIA

2h 12mnonstop

5:45 am - 7:47 amMIA-CLT

2h 02mnonstop

$97Multiple Airlines

Find Deal

Fri, Nov 14 - Sun, Nov 16

8:52 pm - 11:04 pmCLT-MIA

2h 12mnonstop

6:46 am - 8:49 amMIA-CLT

2h 03mnonstop

$100Spirit Airlines

Find Deal

Thu, Nov 20 - Sun, Nov 23

11:55 am - 1:28 pmSAV-MIA

1h 33mnonstop

5:58 pm - 7:40 pmMIA-SAV

1h 42mnonstop

$139American Airlines

Find Deal

Sat, Jan 10 - Wed, Jan 14

5:25 am - 11:21 amCHS-MIA

5h 56m1 stop

6:30 pm - 11:50 pmMIA-CHS

5h 20m1 stop

$157Delta

Find Deal

Mon, Dec 8 - Fri, Dec 12

5:30 am - 9:24 amSAV-MIA

3h 54m1 stop

7:15 am - 1:46 pmMIA-SAV

6h 31m1 stop

$159Delta

Find Deal

Sat, Jan 10 - Sat, Jan 17

8:07 pm - 10:00 pmCHS-MIA

1h 53mnonstop

7:00 am - 8:47 amMIA-CHS

1h 47mnonstop

$160American Airlines

Find Deal

Fri, Jan 2 - Mon, Jan 5

American Airlines flights from South Carolina to Florida Keys

Our best American Airlines deals on South Carolina to Florida Keys flight tickets

American Airlines

Jan 10

SAV11:55 amSavannah/Hilton Head

1h 33m

MIA1:28 pmMiami

Jan 14

MIA5:58 pmMiami

1h 42m

SAV7:40 pmSavannah/Hilton Head

$139

Find similar

American Airlines

Jan 2

CHS8:07 pmCharleston

1h 53m

MIA10:00 pmMiami

Jan 5

MIA7:00 amMiami

1h 47m

CHS8:47 amCharleston

$160

Find similar

American Airlines

Jan 15

CHS7:28 pmCharleston

1h 57m

MIA9:25 pmMiami

Jan 18

MIA10:08 pmMiami

1h 47m

CHS11:55 pmCharleston

$167

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Frontier flights from South Carolina to Florida Keys

Our best Frontier deals on South Carolina to Florida Keys flight tickets

Frontier

Nov 13

CLT10:42 pmCharlotte Douglas

2h 12m

MIA12:54 amMiami

Nov 28

MIA7:00 amMiami

2h 18m

CLT9:18 amCharlotte Douglas

$90

Find similar

Frontier

Nov 16

CLT10:42 pmCharlotte Douglas

2h 12m

MIA12:54 amMiami

Nov 21

MIA7:00 amMiami

2h 18m

CLT9:18 amCharlotte Douglas

$92

Find similar

Frontier

Dec 23

CLT7:46 pmCharlotte Douglas

2h 13m

MIA9:59 pmMiami

Jan 1

MIA2:22 pmMiami

2h 16m

CLT4:38 pmCharlotte Douglas

$96

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momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Thu 11/13

10:42 pm-12:54 am

Nonstop2h 12m

Miami

Fri 11/28

7:00 am-9:18 am

Nonstop2h 18m

$90

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Fri 11/14

10:42 pm-12:54 am

Nonstop2h 12m

Miami

Sun 11/16

5:45 am-7:47 am

Nonstop2h 02m

$91

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 11/16

10:42 pm-12:54 am

Nonstop2h 12m

Miami

Fri 11/21

7:00 am-9:18 am

Nonstop2h 18m

$92

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 11/16

9:38 pm-11:51 pm

Nonstop2h 13m

Miami

Sun 11/23

6:46 am-8:49 am

Nonstop2h 03m

$93

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Fri 11/14

10:42 pm-12:54 am

Nonstop2h 12m

Miami

Sun 11/16

5:45 am-7:47 am

Nonstop2h 02m

$97

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Thu 11/20

8:52 pm-11:04 pm

Nonstop2h 12m

Miami

Sun 11/23

6:46 am-8:49 am

Nonstop2h 03m

$100

SavannahMiami

SAV - MIA

SAVMIA

Savannah/Hilton Head

Sat 1/10

11:55 am-1:28 pm

Nonstop1h 33m

Miami

Wed 1/14

5:58 pm-7:40 pm

Nonstop1h 42m

$139

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 12/8

5:25 am-11:21 am

1 stop5h 56m

Miami

Fri 12/12

6:30 pm-11:50 pm

1 stop5h 20m

$157

SavannahMiami

SAV - MIA

SAVMIA

Savannah/Hilton Head

Sat 1/10

5:30 am-9:24 am

1 stop3h 54m

Miami

Sat 1/17

7:15 am-1:46 pm

1 stop6h 31m

$159

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 1/2

8:07 pm-10:00 pm

Nonstop1h 53m

Miami

Mon 1/5

7:00 am-8:47 am

Nonstop1h 47m

$160

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How to get the cheapest flight ticket from South Carolina to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $266.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Wednesday when prices can be found for as low as $487. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $561.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from South Carolina to Florida Keys in the evening for as low as $362. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the afternoon are often more expensive with an average ticket price of $603.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $296 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from South Carolina for as low as $254 on momondo.

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time	1h 27m
Direct flights	Every day
Airports in Florida Keys	1 airport

The fastest flight from South Carolina to Florida Keys takes 1h 27m

Direct flights go from South Carolina to Florida Keys every day.

There is 1 airport near Florida Keys: Miami (MIA)

Search flight deals

When did momondo last update prices for flights from South Carolina to Florida Keys?
Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Florida Keys?
There are 9 operators available for flights from South Carolina to Florida Keys as of November 2025.
How old do you have to be to fly from South Carolina to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Florida Keys?
Based on momondo bookings for flights between South Carolina and Florida Keys, the leading plane model is Airbus A220-300, making up 16.66% of the total bookings. Other popular models include Canadair (Bombardier) Regional Jet 900 with 11.95%, Airbus A320-100/200 with 11.42%, and Embraer 175 with 10.85%.

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $110	Free Cancellation	Rating 8.1 226 reviews	Search Breeze Airways flights
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,003 reviews	Search Delta flights
American Airlines	PriceFrom $253	Free Cancellation	Rating 7.2 11,044 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from South Carolina.

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

All flight searches from South Carolina to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Florida Keys.

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Popular cities in Florida Keys

Flights to New Yorkfrom $44

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Flights to Chicagofrom $54

Flights to Orlandofrom $49

Flights to Las Vegasfrom $42

Flights to San Franciscofrom $57

Flights to Washington, D.C.from $49

Flights to Bostonfrom $49

Flights to Atlantafrom $40

Flights to Dallasfrom $59

Flights to Seattlefrom $58

Cheap flights from South Carolina to Florida Keys from $44

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Florida Keys departing on 11/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from South Carolina to Florida Keys

Cheap round-trip flights

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Cheap last minute flights

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American Airlines flights from South Carolina to Florida Keys

Our best American Airlines deals on South Carolina to Florida Keys flight tickets

Frontier flights from South Carolina to Florida Keys

Our best Frontier deals on South Carolina to Florida Keys flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

See travel insights to Florida Keys from

How to get the cheapest flight ticket from South Carolina to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $266.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Wednesday when prices can be found for as low as $487. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $561.

What is the cheapest time of day to depart on your flight to Florida Keys?

How far in advance should I book a flight to Florida Keys?

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

What is the cheapest airline that flies from South Carolina to Florida Keys?

Frontier, American Airlines, and Spirit Airlines are the most popular carriers operating from South Carolina to Florida Keys

What airlines fly to Florida Keys?

How many flights depart from South Carolina to Florida Keys on average per week?

As of November 2025, there are 285 flights per week flying from South Carolina to Florida Keys. The most common day of the week flights depart is Thu, with 17% of flights taking off on this day.

How long is the flight from South Carolina to Florida Keys?

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time

Direct flights

Airports in Florida Keys

When did momondo last update prices for flights from South Carolina to Florida Keys?

How many operators does momondo search for flights from South Carolina to Florida Keys?

How old do you have to be to fly from South Carolina to Florida Keys?

What documentation or ID do you need to fly to Florida Keys?

What is the most popular plane model from South Carolina to Florida Keys?

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Florida Keys?

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo