What is the cheapest airline that flies from South Carolina to Florida Keys?

Frontier, Spirit Airlines, and Breeze Airways are the most popular carriers operating from South Carolina to Florida Keys

How long is the flight from South Carolina to Florida Keys?

On average, it takes 14h 53m to fly from South Carolina to Florida Keys if you fly out of Greenville (the most popular airport in South Carolina) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Myrtle Beach and into Copenhagen, then the flight time is around 16h 12m.

How many flights depart from South Carolina to Florida Keys on average per week?

As of February 2026, there are 257 flights per week flying from South Carolina to Florida Keys. The most common day of the week flights depart is Sun, with 19% of flights taking off on this day.

What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from South Carolina according to our data. American Airlines is the first choice among our users, with 68% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Carolina to Florida Keys?

Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Florida Keys?

There are 8 operators available for flights from South Carolina to Florida Keys as of February 2026.

How old do you have to be to fly from South Carolina to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$38 Cheap Flights from South Carolina to Florida Keys in 2026

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Find the cheapest flights from South Carolina to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:53 pm - 12:05 am

CLT

MIA

2h 12mnonstop

7:55 am - 10:12 am

MIA

CLT

2h 17mnonstop

$79Frontier

Mon, Mar 9 - Fri, Mar 13

2:28 pm - 4:45 pm

CLT

MIA

2h 17mnonstop

11:17 am - 1:43 pm

MIA

CLT

2h 26mnonstop

$80Frontier

Thu, Apr 23 - Mon, Apr 27

7:00 am - 9:10 am

CLT

MIA

2h 10mnonstop

10:05 am - 12:20 pm

MIA

CLT

2h 15mnonstop

$81Spirit Airlines

Tue, Feb 24 - Tue, Mar 3

7:00 am - 9:02 am

CLT

MIA

2h 02mnonstop

7:15 am - 9:32 am

MIA

CLT

2h 17mnonstop

$82Multiple Airlines

Sun, Mar 22 - Sat, Mar 28

7:00 am - 9:02 am

CLT

MIA

2h 02mnonstop

7:55 am - 10:12 am

MIA

CLT

2h 17mnonstop

$83Multiple Airlines

Sat, Mar 14 - Mon, Mar 16

7:00 am - 9:02 am

CLT

MIA

2h 02mnonstop

9:57 am - 12:07 pm

MIA

CLT

2h 10mnonstop

$86Spirit Airlines

Mon, Apr 6 - Thu, Apr 9

3:01 pm - 12:26 pm

CHS

EYW

21h 25m

1 stop

9:49 am - 9:53 pm

EYW

CHS

12h 04m

1 stop

$150Breeze Airways

Sun, Feb 22 - Fri, Feb 27

3:01 pm - 12:26 pm

CHS

EYW

21h 25m

1 stop

9:49 am - 9:53 pm

EYW

CHS

12h 04m

1 stop

$165Breeze Airways

Sun, Feb 22 - Fri, Feb 27

5:48 pm - 7:36 pm

SAV

MIA

1h 48mnonstop

10:19 pm - 11:59 pm

MIA

SAV

1h 40mnonstop

$194American Airlines

Sat, Feb 21 - Thu, Feb 26

7:26 pm - 9:23 pm

GSP

MIA

1h 57mnonstop

4:48 pm - 6:56 pm

MIA

GSP

2h 08mnonstop

$219American Airlines

Tue, Mar 17 - Tue, Mar 24

Frontier flights from South Carolina to Florida Keys

Our best Frontier deals on South Carolina to Florida Keys flight tickets

Frontier

Mar 9

CLT9:53 pmCharlotte Douglas

2h 12m

MIA12:05 amMiami

Mar 13

MIA7:55 amMiami

2h 17m

CLT10:12 amCharlotte Douglas

$79

Frontier

Apr 23

CLT2:28 pmCharlotte Douglas

2h 17m

MIA4:45 pmMiami

Apr 27

MIA11:17 amMiami

2h 26m

CLT1:43 pmCharlotte Douglas

$80

Frontier

Feb 26

CLT2:21 pmCharlotte Douglas

2h 15m

MIA4:36 pmMiami

Mar 5

MIA3:30 pmMiami

2h 20m

CLT5:50 pmCharlotte Douglas

$85

Spirit Airlines flights from South Carolina to Florida Keys

Our best Spirit Airlines deals on South Carolina to Florida Keys flight tickets

Spirit Airlines

Feb 24

CLT7:00 amCharlotte Douglas

2h 10m

MIA9:10 amMiami

Mar 3

MIA10:05 amMiami

2h 15m

CLT12:20 pmCharlotte Douglas

$81

Spirit Airlines

Apr 6

CLT7:00 amCharlotte Douglas

2h 02m

MIA9:02 amMiami

Apr 9

MIA9:57 amMiami

2h 10m

CLT12:07 pmCharlotte Douglas

$86

Spirit Airlines

Feb 9

CLT7:00 amCharlotte Douglas

2h 10m

MIA9:10 amMiami

Feb 12

MIA10:05 amMiami

2h 15m

CLT12:20 pmCharlotte Douglas

$87

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Mon 3/9

9:53 pm-12:05 am

Nonstop2h 12m

Miami

Fri 3/13

7:55 am-10:12 am

Nonstop2h 17m

$79

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Thu 4/23

2:28 pm-4:45 pm

Nonstop2h 17m

Miami

Mon 4/27

11:17 am-1:43 pm

Nonstop2h 26m

$80

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Tue 2/24

7:00 am-9:10 am

Nonstop2h 10m

Miami

Tue 3/3

10:05 am-12:20 pm

Nonstop2h 15m

$81

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 3/22

7:00 am-9:02 am

Nonstop2h 02m

Miami

Sat 3/28

7:15 am-9:32 am

Nonstop2h 17m

$82

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sat 3/14

7:00 am-9:02 am

Nonstop2h 02m

Miami

Mon 3/16

7:55 am-10:12 am

Nonstop2h 17m

$83

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Mon 4/6

7:00 am-9:02 am

Nonstop2h 02m

Miami

Thu 4/9

9:57 am-12:07 pm

Nonstop2h 10m

$86

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sun 2/22

3:01 pm-12:26 pm

1 stop21h 25m

Key West

Fri 2/27

9:49 am-9:53 pm

1 stop12h 04m

$150

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sun 2/22

3:01 pm-12:26 pm

1 stop21h 25m

Key West

Fri 2/27

9:49 am-9:53 pm

1 stop12h 04m

$165

SavannahMiami

SAV - MIA

SAVMIA

Savannah/Hilton Head

Sat 2/21

5:48 pm-7:36 pm

Nonstop1h 48m

Miami

Thu 2/26

10:19 pm-11:59 pm

Nonstop1h 40m

$194

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 3/17

7:26 pm-9:23 pm

Nonstop1h 57m

Miami

Tue 3/24

4:48 pm-6:56 pm

Nonstop2h 08m

$219

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $263.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Friday when prices can be found for as low as $484. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $549.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from South Carolina to Florida Keys in the afternoon for as low as $287. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $526.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $291 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from South Carolina for as low as $235 on momondo.

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time	1h 37m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from South Carolina to Florida Keys takes 1h 37m

Direct flights go from South Carolina to Florida Keys every day.

There are 3 airports in Florida Keys. From South Carolina there are direct flights to Miami (MIA).

Search flight deals

When did momondo last update prices for flights from South Carolina to Florida Keys?
Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Florida Keys?
There are 8 operators available for flights from South Carolina to Florida Keys as of February 2026.
How old do you have to be to fly from South Carolina to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Florida Keys?
Based on momondo bookings for flights between South Carolina and Florida Keys, the leading plane model is Airbus A220-300, making up 18.79% of the total bookings. Other popular models include Embraer 175 with 12.20%, Canadair (Bombardier) Regional Jet 900 with 11.13%, and Embraer 175 (Enhanced Winglets) with 8.68%.

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $95	Free Cancellation	Rating 8.1 267 reviews	Search Breeze Airways flights
Delta	PriceFrom $125	Free Cancellation	Rating 7.9 8,174 reviews	Search Delta flights
American Airlines	PriceFrom $253	Free Cancellation	Rating 7.2 11,258 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from South Carolina.

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

All flight searches from South Carolina to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Florida Keys.

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Popular cities in Florida Keys

Flights to New Yorkfrom $49

Flights to Los Angelesfrom $49

Flights to Miamifrom $36

Flights to Chicagofrom $50

Flights to Orlandofrom $27

Flights to San Franciscofrom $51

Flights to Las Vegasfrom $28

Flights to Washington, D.C.from $51

Flights to Bostonfrom $50

Flights to Atlantafrom $49

Flights to Dallasfrom $50

Flights to Seattlefrom $65

Cheap flights from South Carolina to Florida Keys from $38

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Florida Keys departing on 3/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from South Carolina to Florida Keys

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

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Frontier flights from South Carolina to Florida Keys

Our best Frontier deals on South Carolina to Florida Keys flight tickets

Spirit Airlines flights from South Carolina to Florida Keys

Our best Spirit Airlines deals on South Carolina to Florida Keys flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

See travel insights to Florida Keys from

How to get the cheapest flight ticket from South Carolina to Florida Keys

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $263.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Friday when prices can be found for as low as $484. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $549.

What is the cheapest time of day to depart on your flight to Florida Keys?

How far in advance should I book a flight to Florida Keys?

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

What is the cheapest airline that flies from South Carolina to Florida Keys?

Frontier, Spirit Airlines, and Breeze Airways are the most popular carriers operating from South Carolina to Florida Keys

What airlines fly to Florida Keys?

How many flights depart from South Carolina to Florida Keys on average per week?

As of February 2026, there are 257 flights per week flying from South Carolina to Florida Keys. The most common day of the week flights depart is Sun, with 19% of flights taking off on this day.

How long is the flight from South Carolina to Florida Keys?

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time

Direct flights

Airports in Florida Keys

When did momondo last update prices for flights from South Carolina to Florida Keys?

How many operators does momondo search for flights from South Carolina to Florida Keys?

How old do you have to be to fly from South Carolina to Florida Keys?

What documentation or ID do you need to fly to Florida Keys?

What is the most popular plane model from South Carolina to Florida Keys?

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Florida Keys?

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo

South Carolina flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Florida Keys

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Complete your trip to Florida Keys

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According to popular flight searches on momondo this year