How many flights depart from South Carolina to Florida Keys on average per week?

As of December 2025, there are 234 flights per week flying from South Carolina to Florida Keys. The most common day of the week flights depart is Tue, with 21% of flights taking off on this day.

How long is the flight from South Carolina to Florida Keys?

On average, it takes 5h 25m to fly from South Carolina to Florida Keys if you fly out of Charleston (the most popular airport in South Carolina) and into Los Angeles (the most popular airport in Florida Keys). If you’re flying out of Greenville and into Los Angeles, then the flight time is around 5h 40m.

What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from South Carolina according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Carolina to Florida Keys?

Spirit Airlines, American Airlines, and Frontier are the most popular carriers operating from South Carolina to Florida Keys

When did momondo last update prices for flights from South Carolina to Florida Keys?

Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Florida Keys?

There are 9 operators available for flights from South Carolina to Florida Keys as of December 2025.

How old do you have to be to fly from South Carolina to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$40 Cheap Flights from South Carolina to Florida Keys in 2025/26

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Find the cheapest flights from South Carolina to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:42 pm - 9:55 pm

CLT

MIA

2h 13mnonstop

7:05 am - 9:36 am

MIA

CLT

2h 31mnonstop

$87Frontier

Sun, Jan 4 - Fri, Jan 9

9:19 pm - 11:29 pm

CLT

MIA

2h 10mnonstop

12:55 pm - 3:25 pm

MIA

CLT

2h 30mnonstop

$88Frontier

Sun, Feb 8 - Fri, Feb 13

10:34 am - 12:46 pm

CLT

MIA

2h 12mnonstop

7:05 am - 9:36 am

MIA

CLT

2h 31mnonstop

$89Multiple Airlines

Sun, Jan 4 - Fri, Jan 9

9:19 pm - 11:29 pm

CLT

MIA

2h 10mnonstop

10:06 am - 12:22 pm

MIA

CLT

2h 16mnonstop

$90Multiple Airlines

Sun, Feb 1 - Sun, Feb 8

3:15 pm - 11:59 pm

CLT

MIA

8h 44m1 stop

8:15 am - 10:38 am

MIA

CLT

2h 23mnonstop

$91Multiple Airlines

Wed, Jan 28 - Fri, Feb 6

6:00 am - 7:40 am

SAV

MIA

1h 40mnonstop

10:16 pm - 11:58 pm

MIA

SAV

1h 42mnonstop

$139American Airlines

Tue, Jan 20 - Sat, Jan 24

9:27 am - 11:20 am

CHS

MIA

1h 53mnonstop

10:08 pm - 11:55 pm

MIA

CHS

1h 47mnonstop

$142American Airlines

Mon, Jan 5 - Thu, Jan 8

3:39 pm - 9:05 pm

MYR

MIA

29h 26m1 stop

12:56 pm - 9:04 pm

MIA

MYR

8h 08m1 stop

$149Spirit Airlines

Wed, Jan 21 - Wed, Jan 28

7:55 am - 4:10 pm

CHS

MIA

8h 15m1 stop

7:50 am - 1:15 pm

MIA

CHS

5h 25m1 stop

$151Southwest

Thu, Jan 29 - Sat, Jan 31

5:05 pm - 8:13 pm

CHS

MIA

27h 08m1 stop

11:38 am - 4:10 pm

MIA

CHS

28h 32m1 stop

$161Spirit Airlines

Fri, Jan 23 - Thu, Jan 29

American Airlines flights from South Carolina to Florida Keys

Our best American Airlines deals on South Carolina to Florida Keys flight tickets

American Airlines

Jan 20

SAV6:00 amSavannah/Hilton Head

1h 40m

MIA7:40 amMiami

Jan 24

MIA10:16 pmMiami

1h 42m

SAV11:58 pmSavannah/Hilton Head

$139

Find similar

American Airlines

Jan 5

CHS9:27 amCharleston

1h 53m

MIA11:20 amMiami

Jan 8

MIA10:08 pmMiami

1h 47m

CHS11:55 pmCharleston

$142

Find similar

American Airlines

Jan 17

SAV6:00 amSavannah/Hilton Head

1h 40m

MIA7:40 amMiami

Jan 30

MIA10:16 pmMiami

1h 42m

SAV11:58 pmSavannah/Hilton Head

$149

Find similar

Delta flights from South Carolina to Florida Keys

Our best Delta deals on South Carolina to Florida Keys flight tickets

Delta

Jan 8

CHS6:30 amCharleston

4h 10m

1 stop

MIA10:40 amMiami

Jan 12

MIA5:50 amMiami

5h 58m

1 stop

CHS11:48 amCharleston

$157

Find similar

Delta

Jan 31

SAV5:30 amSavannah/Hilton Head

3h 56m

1 stop

MIA9:26 amMiami

Feb 4

MIA5:50 amMiami

5h 39m

1 stop

SAV11:29 amSavannah/Hilton Head

$159

Find similar

Delta

Jan 5

CHS5:30 pmCharleston

5h 18m

1 stop

MIA10:48 pmMiami

Jan 8

MIA4:32 pmMiami

4h 23m

1 stop

CHS8:55 pmCharleston

$172

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 1/4

7:42 pm-9:55 pm

Nonstop2h 13m

Miami

Fri 1/9

7:05 am-9:36 am

Nonstop2h 31m

$87

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 2/8

9:19 pm-11:29 pm

Nonstop2h 10m

Miami

Fri 2/13

12:55 pm-3:25 pm

Nonstop2h 30m

$88

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 1/4

10:34 am-12:46 pm

Nonstop2h 12m

Miami

Fri 1/9

7:05 am-9:36 am

Nonstop2h 31m

$89

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 2/1

9:19 pm-11:29 pm

Nonstop2h 10m

Miami

Sun 2/8

10:06 am-12:22 pm

Nonstop2h 16m

$90

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Wed 1/28

3:15 pm-11:59 pm

1 stop8h 44m

Miami

Fri 2/6

8:15 am-10:38 am

Nonstop2h 23m

$91

SavannahMiami

SAV - MIA

SAVMIA

Savannah/Hilton Head

Tue 1/20

6:00 am-7:40 am

Nonstop1h 40m

Miami

Sat 1/24

10:16 pm-11:58 pm

Nonstop1h 42m

$139

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 1/5

9:27 am-11:20 am

Nonstop1h 53m

Miami

Thu 1/8

10:08 pm-11:55 pm

Nonstop1h 47m

$142

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 1/21

3:39 pm-9:05 pm

1 stop29h 26m

Miami

Wed 1/28

12:56 pm-9:04 pm

1 stop8h 08m

$149

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Thu 1/29

7:55 am-4:10 pm

1 stop8h 15m

Miami

Sat 1/31

7:50 am-1:15 pm

1 stop5h 25m

$151

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 1/23

5:05 pm-8:13 pm

1 stop27h 08m

Miami

Thu 1/29

11:38 am-4:10 pm

1 stop28h 32m

$161

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $266.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Thursday when prices can be found for as low as $483. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $564.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from South Carolina to Florida Keys in the afternoon for as low as $309. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $533.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $293 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from South Carolina for as low as $243 on momondo.

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time	1h 40m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from South Carolina to Florida Keys takes 1h 40m

Direct flights go from South Carolina to Florida Keys every day.

There are 3 airports in Florida Keys. From South Carolina there are direct flights to Miami (MIA).

Search flight deals

When did momondo last update prices for flights from South Carolina to Florida Keys?
Prices for flights from South Carolina to Florida Keys are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Florida Keys?
There are 9 operators available for flights from South Carolina to Florida Keys as of December 2025.
How old do you have to be to fly from South Carolina to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Florida Keys?
Based on momondo bookings for flights between South Carolina and Florida Keys, the leading plane model is Airbus A220-300, making up 16.62% of the total bookings. Other popular models include Canadair (Bombardier) Regional Jet 900 with 11.94%, Embraer 175 with 11.19%, and Airbus A320-100/200 with 8.80%.

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $110	Free Cancellation	Rating 8.2 249 reviews	Search Breeze Airways flights
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,013 reviews	Search Delta flights
American Airlines	PriceFrom $253	Free Cancellation	Rating 7.2 11,052 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from South Carolina.

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

All flight searches from South Carolina to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Florida Keys.

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Popular cities in Florida Keys

Flights to New Yorkfrom $50

Flights to Los Angelesfrom $49

Flights to Miamifrom $50

Flights to Chicagofrom $51

Flights to Orlandofrom $50

Flights to San Franciscofrom $53

Flights to Las Vegasfrom $38

Flights to Washington, D.C.from $58

Flights to Bostonfrom $50

Flights to Atlantafrom $47

Flights to Dallasfrom $51

Flights to Seattlefrom $55

Cheap flights from South Carolina to Florida Keys from $40

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Florida Keys departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from South Carolina to Florida Keys

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

American Airlines flights from South Carolina to Florida Keys

Our best American Airlines deals on South Carolina to Florida Keys flight tickets

Delta flights from South Carolina to Florida Keys

Our best Delta deals on South Carolina to Florida Keys flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.

See travel insights to Florida Keys from

How to get the cheapest flight ticket from South Carolina to Florida Keys

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from South Carolina averaging around $266.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from South Carolina to Florida Keys is on a Thursday when prices can be found for as low as $483. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $564.

What is the cheapest time of day to depart on your flight to Florida Keys?

How far in advance should I book a flight to Florida Keys?

Can stopping save me money on South Carolina to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Florida Keys.

What is the cheapest airline that flies from South Carolina to Florida Keys?

Spirit Airlines, American Airlines, and Frontier are the most popular carriers operating from South Carolina to Florida Keys

What airlines fly to Florida Keys?

How many flights depart from South Carolina to Florida Keys on average per week?

As of December 2025, there are 234 flights per week flying from South Carolina to Florida Keys. The most common day of the week flights depart is Tue, with 21% of flights taking off on this day.

How long is the flight from South Carolina to Florida Keys?

Cheap South Carolina to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Florida Keys

Fastest flight time

Direct flights

Airports in Florida Keys

When did momondo last update prices for flights from South Carolina to Florida Keys?

How many operators does momondo search for flights from South Carolina to Florida Keys?

How old do you have to be to fly from South Carolina to Florida Keys?

What documentation or ID do you need to fly to Florida Keys?

What is the most popular plane model from South Carolina to Florida Keys?

Best airlines flying from South Carolina to Florida Keys

Compare and see reviews for airlines that fly from South Carolina to Florida Keys with momondo

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Florida Keys?

Can I find flights from South Carolina to Florida Keys with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Florida Keys?

I’m not ready to book a flight from South Carolina to Florida Keys right now. Can momondo alert me if prices change?

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo