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Cheap flights from Sioux Falls to South Carolina from $153

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to South Carolina departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Sioux Falls to South Carolina

Cheap round-trip flights

Logo
8:11 pm - 10:58 pmFSD-CLT
25h 47m2 stops
Logo
3:10 pm - 8:38 amCLT-FSD
18h 28m2 stops
$255
Find Deal
Mon, Aug 25 - Thu, Aug 28
Delta Logo
5:27 am - 11:14 amFSD-SAV
4h 47m1 stop
Delta Logo
5:05 pm - 11:06 pmSAV-FSD
7h 01m1 stop
$259Delta
Find Deal
Tue, Aug 26 - Sat, Aug 30
Delta Logo
8:01 am - 2:12 pmFSD-CHS
5h 11m1 stop
Delta Logo
4:30 pm - 10:11 pmCHS-FSD
6h 41m1 stop
$259Delta
Find Deal
Sat, Nov 8 - Wed, Nov 12
Logo
8:11 pm - 11:20 pmFSD-CLT
26h 09m3 stops
Logo
3:10 pm - 8:38 amCLT-FSD
18h 28m2 stops
$261
Find Deal
Mon, Aug 25 - Thu, Aug 28
American Airlines Logo
5:30 am - 1:17 pmFSD-CHS
6h 47m1 stop
American Airlines Logo
5:45 am - 2:45 pmCHS-FSD
10h 00m2 stops
$264American Airlines
Find Deal
Sat, Nov 8 - Wed, Nov 12
Delta Logo
5:27 am - 1:38 pmFSD-SAV
7h 11m1 stop
Delta Logo
6:50 am - 12:16 pmSAV-FSD
6h 26m2 stops
$264Delta
Find Deal
Tue, Aug 26 - Sat, Aug 30
American Airlines Logo
5:30 am - 2:46 pmFSD-CHS
8h 16m2 stops
American Airlines Logo
5:45 am - 2:45 pmCHS-FSD
10h 00m2 stops
$269American Airlines
Find Deal
Sat, Nov 8 - Wed, Nov 12
Delta Logo
5:27 am - 5:57 pmFSD-SAV
11h 30m2 stops
Delta Logo
6:50 am - 12:16 pmSAV-FSD
6h 26m2 stops
$269Delta
Find Deal
Tue, Aug 26 - Sat, Aug 30
United Airlines Logo
8:00 am - 2:42 pmFSD-MYR
5h 42m1 stop
United Airlines Logo
3:45 pm - 11:00 pmMYR-FSD
8h 15m1 stop
$400United Airlines
Find Deal
Tue, Aug 26 - Sat, Aug 30
United Airlines Logo
3:08 pm - 9:49 pmFSD-SAV
5h 41m1 stop
United Airlines Logo
7:00 am - 4:06 pmSAV-FSD
10h 06m2 stops
$404United Airlines
Find Deal
Fri, Jan 2 - Thu, Jan 8

American Airlines flights from Sioux Falls to South Carolina

Our best American Airlines deals on Sioux Falls to South Carolina flight tickets
American Airlines
Nov 8
FSD5:30 amSioux Falls Joe Foss Field
6h 47m
1 stop
CHS1:17 pmCharleston
Nov 12
CHS5:45 amCharleston
10h 00m
2 stops
FSD2:45 pmSioux Falls Joe Foss Field
$264
Find similar
American Airlines
Nov 8
FSD5:30 amSioux Falls Joe Foss Field
8h 16m
2 stops
CHS2:46 pmCharleston
Nov 12
CHS5:45 amCharleston
10h 00m
2 stops
FSD2:45 pmSioux Falls Joe Foss Field
$269
Find similar
American Airlines
Aug 14
FSD5:15 pmSioux Falls Joe Foss Field
6h 04m
1 stop
CLT12:19 amCharlotte Douglas
Aug 21
CLT8:15 pmCharlotte Douglas
5h 13m
1 stop
FSD12:28 amSioux Falls Joe Foss Field
$274
Find similar

Delta flights from Sioux Falls to South Carolina

Our best Delta deals on Sioux Falls to South Carolina flight tickets
Delta
Nov 8
FSD8:01 amSioux Falls Joe Foss Field
5h 11m
1 stop
CHS2:12 pmCharleston
Nov 12
CHS4:30 pmCharleston
6h 41m
1 stop
FSD10:11 pmSioux Falls Joe Foss Field
$259
Find similar
Delta
Aug 26
FSD5:27 amSioux Falls Joe Foss Field
7h 11m
1 stop
SAV1:38 pmSavannah/Hilton Head
Aug 30
SAV6:50 amSavannah/Hilton Head
6h 26m
2 stops
FSD12:16 pmSioux Falls Joe Foss Field
$264
Find similar
Delta
Aug 26
FSD5:27 amSioux Falls Joe Foss Field
11h 30m
2 stops
SAV5:57 pmSavannah/Hilton Head
Aug 30
SAV6:50 amSavannah/Hilton Head
6h 26m
2 stops
FSD12:16 pmSioux Falls Joe Foss Field
$269
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Sioux Falls to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsCharlotte

FSD - CLT

FSDCLT

Sioux Falls Joe Foss Field

Mon 8/25

8:11 pm-10:58 pm

2 stops25h 47m

Charlotte Douglas

Thu 8/28

3:10 pm-8:38 am

2 stops18h 28m

$255

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

Tue 8/26

5:27 am-11:14 am

1 stop4h 47m

Savannah/Hilton Head

Sat 8/30

5:05 pm-11:06 pm

1 stop7h 01m

$259

Sioux FallsCharleston

FSD - CHS

FSDCHS

Sioux Falls Joe Foss Field

Sat 11/8

8:01 am-2:12 pm

1 stop5h 11m

Charleston

Wed 11/12

4:30 pm-10:11 pm

1 stop6h 41m

$259

Sioux FallsCharlotte

FSD - CLT

FSDCLT

Sioux Falls Joe Foss Field

Mon 8/25

8:11 pm-11:20 pm

3 stops26h 09m

Charlotte Douglas

Thu 8/28

3:10 pm-8:38 am

2 stops18h 28m

$261

Sioux FallsCharleston

FSD - CHS

FSDCHS

Sioux Falls Joe Foss Field

Sat 11/8

5:30 am-1:17 pm

1 stop6h 47m

Charleston

Wed 11/12

5:45 am-2:45 pm

2 stops10h 00m

$264

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

Tue 8/26

5:27 am-1:38 pm

1 stop7h 11m

Savannah/Hilton Head

Sat 8/30

6:50 am-12:16 pm

2 stops6h 26m

$264

Sioux FallsCharleston

FSD - CHS

FSDCHS

Sioux Falls Joe Foss Field

Sat 11/8

5:30 am-2:46 pm

2 stops8h 16m

Charleston

Wed 11/12

5:45 am-2:45 pm

2 stops10h 00m

$269

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

Tue 8/26

5:27 am-5:57 pm

2 stops11h 30m

Savannah/Hilton Head

Sat 8/30

6:50 am-12:16 pm

2 stops6h 26m

$269

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 8/26

8:00 am-2:42 pm

1 stop5h 42m

Myrtle Beach Intl

Sat 8/30

3:45 pm-11:00 pm

1 stop8h 15m

$400

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

Fri 1/2

3:08 pm-9:49 pm

1 stop5h 41m

Savannah/Hilton Head

Thu 1/8

7:00 am-4:06 pm

2 stops10h 06m

$404

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Sioux Falls to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Sioux Falls is in November. Flight prices, which tend to average around $263, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to South Carolina from Sioux Falls during June instead. Flights to South Carolina in June, while not as cheap as those in November, still average around $323.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Saturday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $349. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $565.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Sioux Falls to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $408. Try not to purchase tickets in the morning because they tend to be around $428. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Sioux Falls to South Carolina flights?

You could potentially save up to 5% on your flight if you consider stops on a Sioux Falls to South Carolina flight.

Cheap Sioux Falls to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to South Carolina

Best Price Found

$153

Fastest flight time

4h 27m

Direct flights

None

Airports in South Carolina

5 airports
The best one-way flight to South Carolina from Sioux Falls in the past 72 hours is $153. The best round-trip flight deal from Sioux Falls to South Carolina found on momondo in the last 72 hours is $255.
The fastest flight from Sioux Falls to South Carolina takes 4h 27m
There are no direct flights from Sioux Falls to South Carolina. Popular non-direct routes for this connection are Sioux Falls Joe Foss Field Airport - Myrtle Beach Intl Airport, Sioux Falls Joe Foss Field Airport - Savannah/Hilton Head Airport and Sioux Falls Joe Foss Field Airport - Charleston Airport.
There are 5 airports near South Carolina: Columbia Metropolitan (CAE), Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS)
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  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to South Carolina?

    Prices for flights from Sioux Falls Joe Foss Field Airport to South Carolina are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to South Carolina?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Sioux Falls to South Carolina

Compare and see reviews for airlines that fly from Sioux Falls to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $226Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
American AirlinesPriceFrom $238Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $238Free CancellationRating
8.0
7,981 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to South Carolina?

It is quick and easy to find Sioux Falls to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Sioux Falls to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Sioux Falls with this policy.

How can momondo help me find flights from Sioux Falls to South Carolina?

momondo helps you find the best flight between Sioux Falls and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Sioux Falls to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Sioux Falls and alert you when they change.

An easier way to manage your South Carolina trip

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