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Cheap flights from Santiago to St. Louis from $368

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 2/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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LATAM Airlines Logo
6:30 pm - 11:02 am
SCL
-
STL
19h 32m2 stops
LATAM Airlines Logo
6:00 am - 7:40 am
STL
-
SCL
22h 40m1 stop
$805LATAM Airlines
mié., feb. 25 - dom., mar. 1
American Airlines Logo
11:15 pm - 7:29 pm
SCL
-
STL
23h 14m1 stop
American Airlines Logo
11:06 am - 6:50 am
STL
-
SCL
18h 44m1 stop
$818American Airlines
mar., feb. 24 - vie., abr. 24
LATAM Airlines Logo
11:00 pm - 5:54 pm
SCL
-
STL
19h 54m2 stops
LATAM Airlines Logo
9:40 am - 5:35 am
STL
-
SCL
18h 55m2 stops
$821LATAM Airlines
lun., abr. 27 - mié., may. 6
American Airlines Logo
10:15 pm - 10:32 am
SCL
-
STL
15h 17m1 stop
American Airlines Logo
12:11 pm - 6:50 am
STL
-
SCL
17h 39m2 stops
$823American Airlines
mar., feb. 24 - vie., abr. 24
LATAM Airlines Logo
8:15 am - 11:36 pm
SCL
-
STL
18h 21m2 stops
LATAM Airlines Logo
6:00 am - 6:55 am
STL
-
SCL
21h 55m2 stops
$828LATAM Airlines
mié., feb. 25 - dom., mar. 1
Delta Logo
11:10 pm - 9:06 am
SCL
-
STL
12h 56m1 stop
Delta Logo
10:13 am - 7:40 am
STL
-
SCL
18h 27m1 stop
$836Delta
vie., feb. 27 - dom., mar. 1
American Airlines Logo
8:30 pm - 10:16 am
SCL
-
STL
14h 46m1 stop
American Airlines Logo
5:24 am - 6:50 am
STL
-
SCL
24h 26m1 stop
$839American Airlines
lun., abr. 27 - mié., may. 6
LATAM Airlines Logo
11:00 pm - 5:54 pm
SCL
-
STL
19h 54m2 stops
LATAM Airlines Logo
11:43 am - 7:15 am
STL
-
SCL
18h 32m1 stop
$840LATAM Airlines
lun., abr. 27 - mié., may. 6
American Airlines Logo
8:30 pm - 10:16 am
SCL
-
STL
14h 46m1 stop
American Airlines Logo
12:11 pm - 6:50 am
STL
-
SCL
17h 39m2 stops
$843American Airlines
lun., abr. 27 - mié., may. 6
American Airlines Logo
9:20 pm - 5:40 pm
SCL
-
STL
22h 20m1 stop
American Airlines Logo
5:15 am - 8:00 am
STL
-
SCL
24h 45m1 stop
$849American Airlines
vie., mar. 13 - sáb., mar. 28

LATAM Airlines flights from Santiago to St. Louis

Our best LATAM Airlines deals on Santiago to St. Louis flight tickets
LATAM Airlines
Feb 25
SCL6:30 pmSantiago Arturo Merino Benitez
19h 32m
2 stops
STL11:02 amLambert-St Louis
Mar 1
STL6:00 amLambert-St Louis
22h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$805
LATAM Airlines
Apr 27
SCL11:00 pmSantiago Arturo Merino Benitez
19h 54m
2 stops
STL5:54 pmLambert-St Louis
May 6
STL9:40 amLambert-St Louis
18h 55m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
$821
LATAM Airlines
Feb 25
SCL8:15 amSantiago Arturo Merino Benitez
18h 21m
2 stops
STL11:36 pmLambert-St Louis
Mar 1
STL6:00 amLambert-St Louis
21h 55m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
$828

Delta flights from Santiago to St. Louis

Our best Delta deals on Santiago to St. Louis flight tickets
Delta
Feb 27
SCL11:10 pmSantiago Arturo Merino Benitez
12h 56m
1 stop
STL9:06 amLambert-St Louis
Mar 1
STL10:13 amLambert-St Louis
18h 27m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$836
Delta
Apr 24
SCL7:45 pmSantiago Arturo Merino Benitez
20h 54m
2 stops
STL3:39 pmLambert-St Louis
May 1
STL1:11 pmLambert-St Louis
17h 04m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$861
Delta
Apr 24
SCL8:40 pmSantiago Arturo Merino Benitez
14h 54m
1 stop
STL10:34 amLambert-St Louis
May 1
STL7:15 amLambert-St Louis
23h 00m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$921

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 8, 2026.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

mié. 2/25

6:30 pm-11:02 am

2 stops19h 32m

Lambert-St Louis

dom. 3/1

6:00 am-7:40 am

1 stop22h 40m

$805

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

mar. 2/24

11:15 pm-7:29 pm

1 stop23h 14m

Lambert-St Louis

vie. 4/24

11:06 am-6:50 am

1 stop18h 44m

$818

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

lun. 4/27

11:00 pm-5:54 pm

2 stops19h 54m

Lambert-St Louis

mié. 5/6

9:40 am-5:35 am

2 stops18h 55m

$821

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

mar. 2/24

10:15 pm-10:32 am

1 stop15h 17m

Lambert-St Louis

vie. 4/24

12:11 pm-6:50 am

2 stops17h 39m

$823

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

mié. 2/25

8:15 am-11:36 pm

2 stops18h 21m

Lambert-St Louis

dom. 3/1

6:00 am-6:55 am

2 stops21h 55m

$828

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

vie. 2/27

11:10 pm-9:06 am

1 stop12h 56m

Lambert-St Louis

dom. 3/1

10:13 am-7:40 am

1 stop18h 27m

$836

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

lun. 4/27

8:30 pm-10:16 am

1 stop14h 46m

Lambert-St Louis

mié. 5/6

5:24 am-6:50 am

1 stop24h 26m

$839

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

lun. 4/27

11:00 pm-5:54 pm

2 stops19h 54m

Lambert-St Louis

mié. 5/6

11:43 am-7:15 am

1 stop18h 32m

$840

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

lun. 4/27

8:30 pm-10:16 am

1 stop14h 46m

Lambert-St Louis

mié. 5/6

12:11 pm-6:50 am

2 stops17h 39m

$843

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

vie. 3/13

9:20 pm-5:40 pm

1 stop22h 20m

Lambert-St Louis

sáb. 3/28

5:15 am-8:00 am

1 stop24h 45m

$849

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and St. Louis?

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

18h 45m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 18h 45m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 18h 45m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santiago to St. Louis?

Best airlines flying from Santiago to St. Louis

Compare and see reviews for airlines that fly from Santiago to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $877Free CancellationRating
7.9
8,025 reviews
Search Delta flights
American AirlinesPriceFrom $948Free CancellationRating
7.2
11,095 reviews
Search American Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
O'Fallon
Maryland Heights
Florissant
Fenton
Collinsville
St. Peters
Wentzville
Alton
Farmington
Clayton
Eureka
Festus
Edwardsville
Glencoe
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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