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Cheap flights from Santiago to St. Louis from $514

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 8/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
8:40 pm - 3:54 pm
SCL
-
STL
21h 14m
1 stop
Delta Logo
10:05 am - 8:15 am
STL
-
SCL
20h 10m
1 stop
$916Delta
Thu, Sep 10 - Thu, Sep 17
LATAM Airlines Logo
6:40 am - 11:42 pm
SCL
-
STL
19h 02m
2 stops
LATAM Airlines Logo
6:00 am - 7:00 am
STL
-
SCL
23h 00m
2 stops
$919LATAM Airlines
Thu, Sep 10 - Thu, Sep 17
LATAM Airlines Logo
7:10 pm - 12:32 pm
SCL
-
STL
19h 22m
2 stops
LATAM Airlines Logo
10:05 am - 7:00 am
STL
-
SCL
18h 55m
2 stops
$930LATAM Airlines
Thu, Sep 10 - Thu, Sep 17
American Airlines Logo
9:50 pm - 9:49 pm
SCL
-
STL
25h 59m
1 stop
American Airlines Logo
5:10 pm - 7:25 am
STL
-
SCL
12h 15m
1 stop
$940American Airlines
Tue, Sep 8 - Tue, Sep 15
Delta Logo
10:55 pm - 8:33 pm
SCL
-
STL
22h 38m
2 stops
Delta Logo
3:39 pm - 7:15 am
STL
-
SCL
14h 36m
1 stop
$982Delta
Fri, Aug 14 - Mon, Aug 17
LATAM Airlines Logo
8:50 am - 11:54 pm
SCL
-
STL
17h 04m
2 stops
LATAM Airlines Logo
5:35 pm - 3:00 pm
STL
-
SCL
19h 25m
2 stops
$991LATAM Airlines
Sat, Oct 24 - Wed, Oct 28
Delta Logo
8:55 pm - 1:23 pm
SCL
-
STL
18h 28m
2 stops
Delta Logo
10:29 am - 7:25 am
STL
-
SCL
18h 56m
2 stops
$1,048Delta
Sun, Sep 13 - Sun, Sep 20
LATAM Airlines Logo
8:40 pm - 9:09 am
SCL
-
STL
14h 29m
1 stop
LATAM Airlines Logo
12:00 pm - 7:40 am
STL
-
SCL
17h 40m
1 stop
$1,055LATAM Airlines
Sat, Oct 24 - Wed, Oct 28
LATAM Airlines Logo
9:30 am - 10:55 am
SCL
-
STL
27h 25m
3 stops
LATAM Airlines Logo
6:54 pm - 6:25 pm
STL
-
SCL
21h 31m
2 stops
$1,098LATAM Airlines
Sun, Sep 13 - Sun, Sep 20
LATAM Airlines Logo
11:55 pm - 11:42 pm
SCL
-
STL
25h 47m
2 stops
LATAM Airlines Logo
5:46 pm - 7:25 am
STL
-
SCL
35h 39m
2 stops
$1,118LATAM Airlines
Sat, Sep 12 - Sat, Sep 19

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American Airlines flights from Santiago to St. Louis

Our best American Airlines deals on Santiago to St. Louis flight tickets
American Airlines
Aug 3
SCL9:00 pmSantiago Arturo Merino Benitez
14h 24m
1 stop
STL10:24 amLambert-St Louis
Oct 19
STL6:07 pmLambert-St Louis
11h 43m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
$925
American Airlines
Sep 8
SCL9:50 pmSantiago Arturo Merino Benitez
25h 59m
1 stop
STL9:49 pmLambert-St Louis
Sep 15
STL5:10 pmLambert-St Louis
12h 15m
1 stop
SCL7:25 amSantiago Arturo Merino Benitez
$940
American Airlines
Aug 14
SCL8:50 pmSantiago Arturo Merino Benitez
14h 55m
1 stop
STL10:45 amLambert-St Louis
Aug 17
STL5:00 amLambert-St Louis
25h 05m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
$1,146

LATAM Airlines flights from Santiago to St. Louis

Our best LATAM Airlines deals on Santiago to St. Louis flight tickets
LATAM Airlines
Sep 10
SCL6:40 amSantiago Arturo Merino Benitez
19h 02m
2 stops
STL11:42 pmLambert-St Louis
Sep 17
STL6:00 amLambert-St Louis
23h 00m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
$919
LATAM Airlines
Sep 10
SCL7:10 pmSantiago Arturo Merino Benitez
19h 22m
2 stops
STL12:32 pmLambert-St Louis
Sep 17
STL10:05 amLambert-St Louis
18h 55m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
$930
LATAM Airlines
Aug 3
SCL11:00 pmSantiago Arturo Merino Benitez
20h 27m
2 stops
STL6:27 pmLambert-St Louis
Oct 19
STL2:25 pmLambert-St Louis
22h 00m
3 stops
SCL2:25 pmSantiago Arturo Merino Benitez
$961

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2026.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 9/10

8:40 pm-3:54 pm

1 stop21h 14m

Lambert-St Louis

Thu 9/17

10:05 am-8:15 am

1 stop20h 10m

$916

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 9/10

6:40 am-11:42 pm

2 stops19h 02m

Lambert-St Louis

Thu 9/17

6:00 am-7:00 am

2 stops23h 00m

$919

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 9/10

7:10 pm-12:32 pm

2 stops19h 22m

Lambert-St Louis

Thu 9/17

10:05 am-7:00 am

2 stops18h 55m

$930

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 9/8

9:50 pm-9:49 pm

1 stop25h 59m

Lambert-St Louis

Tue 9/15

5:10 pm-7:25 am

1 stop12h 15m

$940

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 8/14

10:55 pm-8:33 pm

2 stops22h 38m

Lambert-St Louis

Mon 8/17

3:39 pm-7:15 am

1 stop14h 36m

$982

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sat 10/24

8:50 am-11:54 pm

2 stops17h 04m

Lambert-St Louis

Wed 10/28

5:35 pm-3:00 pm

2 stops19h 25m

$991

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sun 9/13

8:55 pm-1:23 pm

2 stops18h 28m

Lambert-St Louis

Sun 9/20

10:29 am-7:25 am

2 stops18h 56m

$1,048
Quickest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sat 10/24

8:40 pm-9:09 am

1 stop14h 29m

Lambert-St Louis

Wed 10/28

12:00 pm-7:40 am

1 stop17h 40m

$1,055

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sun 9/13

9:30 am-10:55 am

3 stops27h 25m

Lambert-St Louis

Sun 9/20

6:54 pm-6:25 pm

2 stops21h 31m

$1,098

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sat 9/12

11:55 pm-11:42 pm

2 stops25h 47m

Lambert-St Louis

Sat 9/19

5:46 pm-7:25 am

2 stops35h 39m

$1,118

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Santiago to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $674. The month of December is another great option to travel to St. Louis, with average flight prices from Santiago averaging around $795.

Can stopping save me money on Santiago to St. Louis flights?

You could potentially save up to 27% on your flight if you consider stops on a Santiago to St. Louis flight.

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

20h 27m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 20h 27m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
Search flight deals

Frequently asked questions about flying from Santiago to St. Louis

  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 20h 27m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
St. Peters
Maryland Heights
Florissant
Collinsville
O'Fallon
Alton
Fenton
Farmington
Clayton
Wentzville
Festus
Eureka
Litchfield
Edwardsville
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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