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Cheap flights from Santiago to St. Louis from $406

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 9/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
11:10 pm - 9:17 amSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
13h 07m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:00 am - 7:40 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
22h 40m1 stop Atlanta Hartsfield-Jackson
$925LATAM Airlines
Thu, Nov 5 - Mon, Nov 9
Delta Logo
8:55 pm - 1:23 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
18h 28m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
Delta Logo
7:00 am - 8:15 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
23h 15m1 stop Atlanta Hartsfield-Jackson
$982Delta
Wed, Sep 16 - Sun, Sep 20
LATAM Airlines Logo
8:40 pm - 10:55 amSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
16h 15m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:00 am - 8:15 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
24h 15m1 stop Atlanta Hartsfield-Jackson
$988LATAM Airlines
Thu, Sep 17 - Sun, Sep 20
LATAM Airlines Logo
8:50 am - 11:42 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
16h 52m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
LATAM Airlines Logo
4:59 pm - 6:25 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
23h 26m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$992LATAM Airlines
Wed, Sep 16 - Sun, Sep 20
LATAM Airlines Logo
5:10 am - 11:42 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
20h 32m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:54 pm - 3:00 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
18h 06m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$994LATAM Airlines
Thu, Sep 17 - Sun, Sep 20
Delta Logo
8:40 pm - 11:42 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
29h 02m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 8:15 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
24h 15m1 stop Atlanta Hartsfield-Jackson
$1,048Delta
Sun, Sep 13 - Sun, Sep 20
LATAM Airlines Logo
10:30 pm - 11:42 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
27h 12m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
LATAM Airlines Logo
4:59 pm - 6:25 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
23h 26m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$1,059LATAM Airlines
Sun, Sep 13 - Sun, Sep 20
Delta Logo
11:55 pm - 8:35 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
22h 40m2 stops Miami Detroit Metropolitan Wayne County
Delta Logo
6:54 pm - 3:00 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
18h 06m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$1,070Delta
Sun, Sep 13 - Sun, Sep 20
Multiple Airlines Logo
8:30 am - 5:22 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
33h 52m3 stops Buenos Aires Ministro Pistarini Miami Atlanta Hartsfield-Jackson
Multiple Airlines Logo
5:23 pm - 7:15 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
12h 52m1 stop Atlanta Hartsfield-Jackson
$1,254Multiple Airlines
Sun, Aug 23 - Thu, Aug 27
Multiple Airlines Logo
11:00 pm - 4:31 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
42h 31m2 stops Miami Dallas/Fort Worth
Multiple Airlines Logo
5:23 pm - 7:15 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
12h 52m1 stop Atlanta Hartsfield-Jackson
$1,278Multiple Airlines
Sun, Aug 23 - Thu, Aug 27

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LATAM Airlines flights from Santiago to St. Louis

Our best LATAM Airlines deals on Santiago to St. Louis flight tickets
LATAM Airlines
Nov 5
SCL11:10 pmSantiago Arturo Merino Benitez
13h 07m
1 stop
STL9:17 amLambert-St Louis
Nov 9
STL6:00 amLambert-St Louis
22h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$925
LATAM Airlines
Sep 17
SCL8:40 pmSantiago Arturo Merino Benitez
16h 15m
1 stop
STL10:55 amLambert-St Louis
Sep 20
STL6:00 amLambert-St Louis
24h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$988
LATAM Airlines
Sep 16
SCL8:50 amSantiago Arturo Merino Benitez
16h 52m
2 stops
STL11:42 pmLambert-St Louis
Sep 20
STL4:59 pmLambert-St Louis
23h 26m
2 stops
SCL6:25 pmSantiago Arturo Merino Benitez
$992

Delta flights from Santiago to St. Louis

Our best Delta deals on Santiago to St. Louis flight tickets
Delta
Sep 16
SCL8:55 pmSantiago Arturo Merino Benitez
18h 28m
2 stops
STL1:23 pmLambert-St Louis
Sep 20
STL7:00 amLambert-St Louis
23h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$982
Delta
Sep 13
SCL8:40 pmSantiago Arturo Merino Benitez
29h 02m
1 stop
STL11:42 pmLambert-St Louis
Sep 20
STL6:00 amLambert-St Louis
24h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$1,048
Delta
Sep 13
SCL11:55 pmSantiago Arturo Merino Benitez
22h 40m
2 stops
STL8:35 pmLambert-St Louis
Sep 20
STL6:54 pmLambert-St Louis
18h 06m
2 stops
SCL3:00 pmSantiago Arturo Merino Benitez
$1,070

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Thu 11/5

11:10 pm-9:17 am

1 stop13h 07m

Lambert-St Louis

Mon 11/9

6:00 am-7:40 am

1 stop22h 40m

$925

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Wed 9/16

8:55 pm-1:23 pm

2 stops18h 28m

Lambert-St Louis

Sun 9/20

7:00 am-8:15 am

1 stop23h 15m

$982

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Thu 9/17

8:40 pm-10:55 am

1 stop16h 15m

Lambert-St Louis

Sun 9/20

6:00 am-8:15 am

1 stop24h 15m

$988

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Wed 9/16

8:50 am-11:42 pm

2 stops16h 52m

Lambert-St Louis

Sun 9/20

4:59 pm-6:25 pm

2 stops23h 26m

$992

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Thu 9/17

5:10 am-11:42 pm

2 stops20h 32m

Lambert-St Louis

Sun 9/20

6:54 pm-3:00 pm

2 stops18h 06m

$994

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Sun 9/13

8:40 pm-11:42 pm

1 stop29h 02m

Lambert-St Louis

Sun 9/20

6:00 am-8:15 am

1 stop24h 15m

$1,048

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Sun 9/13

10:30 pm-11:42 pm

2 stops27h 12m

Lambert-St Louis

Sun 9/20

4:59 pm-6:25 pm

2 stops23h 26m

$1,059

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Sun 9/13

11:55 pm-8:35 pm

2 stops22h 40m

Lambert-St Louis

Sun 9/20

6:54 pm-3:00 pm

2 stops18h 06m

$1,070

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Sun 8/23

8:30 am-5:22 pm

3 stops33h 52m

Lambert-St Louis

Thu 8/27

5:23 pm-7:15 am

1 stop12h 52m

$1,254

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Sun 8/23

11:00 pm-4:31 pm

2 stops42h 31m

Lambert-St Louis

Thu 8/27

5:23 pm-7:15 am

1 stop12h 52m

$1,278

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Santiago to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $674. The month of December is another great option to travel to St. Louis, with average flight prices from Santiago averaging around $795.

Can stopping save me money on Santiago to St. Louis flights?

You could potentially save up to 22% on your flight if you consider stops on a Santiago to St. Louis flight.

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

18h 43m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 18h 43m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
Search flight deals

Frequently asked questions about flying from Santiago to St. Louis

  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 18h 43m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
St. Peters
Maryland Heights
Collinsville
Florissant
Alton
O'Fallon
Farmington
Clayton
Fenton
Festus
Wentzville
Eureka
Edwardsville
Litchfield
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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