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Cheap flights from Santiago to St. Louis from $465

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 7/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
8:40 pm - 2:33 pm
SCL
-
STL
18h 53m
1 stop
Delta Logo
11:00 am - 5:55 am
STL
-
SCL
17h 55m
2 stops
$865Delta
Tue, Aug 11 - Tue, Aug 18
Delta Logo
7:55 pm - 12:32 pm
SCL
-
STL
18h 37m
2 stops
Delta Logo
7:05 am - 6:55 am
STL
-
SCL
21h 50m
2 stops
$866Delta
Wed, Sep 9 - Wed, Sep 16
LATAM Airlines Logo
4:50 pm - 12:32 pm
SCL
-
STL
21h 42m
2 stops
LATAM Airlines Logo
10:05 am - 8:15 am
STL
-
SCL
20h 10m
1 stop
$874LATAM Airlines
Wed, Sep 9 - Wed, Sep 16
LATAM Airlines Logo
8:30 am - 9:34 am
SCL
-
STL
27h 04m
3 stops
LATAM Airlines Logo
6:45 pm - 2:05 pm
STL
-
SCL
17h 20m
2 stops
$878LATAM Airlines
Wed, Sep 9 - Wed, Sep 16
American Airlines Logo
8:50 pm - 6:59 pm
SCL
-
STL
23h 09m
2 stops
American Airlines Logo
9:32 am - 7:05 am
STL
-
SCL
20h 33m
2 stops
$879American Airlines
Fri, Aug 21 - Fri, Aug 28
LATAM Airlines Logo
6:45 pm - 11:46 am
SCL
-
STL
18h 01m
2 stops
LATAM Airlines Logo
11:00 am - 1:25 pm
STL
-
SCL
25h 25m
3 stops
$880LATAM Airlines
Tue, Aug 11 - Tue, Aug 18
American Airlines Logo
9:00 pm - 5:21 pm
SCL
-
STL
21h 21m
2 stops
American Airlines Logo
11:35 am - 7:05 am
STL
-
SCL
18h 30m
1 stop
$884American Airlines
Mon, Aug 3 - Sun, Aug 9
American Airlines Logo
9:00 pm - 4:28 pm
SCL
-
STL
20h 28m
2 stops
American Airlines Logo
10:16 am - 7:05 am
STL
-
SCL
19h 49m
2 stops
$906American Airlines
Mon, Aug 3 - Sun, Aug 9
LATAM Airlines Logo
8:40 pm - 6:27 pm
SCL
-
STL
22h 47m
1 stop
LATAM Airlines Logo
5:23 pm - 7:15 am
STL
-
SCL
12h 52m
1 stop
$917LATAM Airlines
Tue, Aug 11 - Tue, Aug 18
LATAM Airlines Logo
8:40 pm - 7:58 pm
SCL
-
STL
25h 18m
1 stop
LATAM Airlines Logo
10:05 am - 8:15 am
STL
-
SCL
20h 10m
1 stop
$931LATAM Airlines
Wed, Sep 9 - Wed, Sep 16

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Delta flights from Santiago to St. Louis

Our best Delta deals on Santiago to St. Louis flight tickets
Delta
Aug 11
SCL8:40 pmSantiago Arturo Merino Benitez
18h 53m
1 stop
STL2:33 pmLambert-St Louis
Aug 18
STL11:00 amLambert-St Louis
17h 55m
2 stops
SCL5:55 amSantiago Arturo Merino Benitez
$865
Delta
Jul 15
SCL8:40 pmSantiago Arturo Merino Benitez
14h 03m
1 stop
STL9:43 amLambert-St Louis
Aug 5
STL11:00 amLambert-St Louis
17h 55m
2 stops
SCL5:55 amSantiago Arturo Merino Benitez
$866
Delta
Jul 14
SCL12:40 amSantiago Arturo Merino Benitez
22h 35m
2 stops
STL10:15 pmLambert-St Louis
Aug 5
STL9:15 amLambert-St Louis
19h 40m
2 stops
SCL5:55 amSantiago Arturo Merino Benitez
$930

American Airlines flights from Santiago to St. Louis

Our best American Airlines deals on Santiago to St. Louis flight tickets
American Airlines
Aug 21
SCL8:50 pmSantiago Arturo Merino Benitez
23h 09m
2 stops
STL6:59 pmLambert-St Louis
Aug 28
STL9:32 amLambert-St Louis
20h 33m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
$879
American Airlines
Aug 3
SCL9:00 pmSantiago Arturo Merino Benitez
21h 21m
2 stops
STL5:21 pmLambert-St Louis
Aug 9
STL11:35 amLambert-St Louis
18h 30m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
$884
American Airlines
Aug 3
SCL9:00 pmSantiago Arturo Merino Benitez
20h 28m
2 stops
STL4:28 pmLambert-St Louis
Aug 9
STL10:16 amLambert-St Louis
19h 49m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
$906

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 8/11

8:40 pm-2:33 pm

1 stop18h 53m

Lambert-St Louis

Tue 8/18

11:00 am-5:55 am

2 stops17h 55m

$865

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 9/9

7:55 pm-12:32 pm

2 stops18h 37m

Lambert-St Louis

Wed 9/16

7:05 am-6:55 am

2 stops21h 50m

$866

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 9/9

4:50 pm-12:32 pm

2 stops21h 42m

Lambert-St Louis

Wed 9/16

10:05 am-8:15 am

1 stop20h 10m

$874

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 9/9

8:30 am-9:34 am

3 stops27h 04m

Lambert-St Louis

Wed 9/16

6:45 pm-2:05 pm

2 stops17h 20m

$878

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 8/21

8:50 pm-6:59 pm

2 stops23h 09m

Lambert-St Louis

Fri 8/28

9:32 am-7:05 am

2 stops20h 33m

$879

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 8/11

6:45 pm-11:46 am

2 stops18h 01m

Lambert-St Louis

Tue 8/18

11:00 am-1:25 pm

3 stops25h 25m

$880

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 8/3

9:00 pm-5:21 pm

2 stops21h 21m

Lambert-St Louis

Sun 8/9

11:35 am-7:05 am

1 stop18h 30m

$884

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 8/3

9:00 pm-4:28 pm

2 stops20h 28m

Lambert-St Louis

Sun 8/9

10:16 am-7:05 am

2 stops19h 49m

$906
Quickest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 8/11

8:40 pm-6:27 pm

1 stop22h 47m

Lambert-St Louis

Tue 8/18

5:23 pm-7:15 am

1 stop12h 52m

$917

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 9/9

8:40 pm-7:58 pm

1 stop25h 18m

Lambert-St Louis

Wed 9/16

10:05 am-8:15 am

1 stop20h 10m

$931

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Santiago to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. The month of December is another great option to travel to St. Louis, with average flight prices from Santiago averaging around $795.

Can stopping save me money on Santiago to St. Louis flights?

You could potentially save up to 32% on your flight if you consider stops on a Santiago to St. Louis flight.

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

18h 37m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 18h 37m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
Search flight deals

Frequently asked questions about flying from Santiago to St. Louis

  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 18h 37m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
Maryland Heights
Florissant
St. Peters
O'Fallon
Collinsville
Alton
Farmington
Wentzville
Clayton
Fenton
Festus
Eureka
Litchfield
Edwardsville
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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