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Cheap flights from Santiago to St. Louis from $790

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 5/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santiago to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
8:40 pm - 12:54 pm
SCL
-
STL
17h 14m1 stop
Delta Logo
5:30 pm - 7:15 am
STL
-
SCL
12h 45m1 stop
$790Delta
Wed, May 20 - Thu, Jun 11
United Airlines Logo
10:45 pm - 3:38 pm
SCL
-
STL
19h 53m1 stop
United Airlines Logo
6:55 pm - 8:50 am
STL
-
SCL
34h 55m2 stops
$792United Airlines
Wed, Feb 25 - Sun, Mar 1
LATAM Airlines Logo
6:30 pm - 11:02 am
SCL
-
STL
19h 32m2 stops
LATAM Airlines Logo
10:13 am - 2:05 pm
STL
-
SCL
24h 52m2 stops
$804LATAM Airlines
Wed, Feb 25 - Sun, Mar 1
Delta Logo
8:40 pm - 12:54 pm
SCL
-
STL
17h 14m1 stop
Delta Logo
1:30 pm - 5:35 am
STL
-
SCL
15h 05m2 stops
$810Delta
Fri, May 22 - Tue, Jun 16
LATAM Airlines Logo
7:05 am - 11:38 pm
SCL
-
STL
17h 33m2 stops
LATAM Airlines Logo
6:00 am - 6:00 am
STL
-
SCL
23h 00m2 stops
$818LATAM Airlines
Thu, May 21 - Sat, Jun 13
LATAM Airlines Logo
8:30 am - 10:45 am
SCL
-
STL
27h 15m3 stops
LATAM Airlines Logo
11:51 am - 6:00 am
STL
-
SCL
17h 09m2 stops
$823LATAM Airlines
Sun, May 24 - Tue, Jun 16
Delta Logo
8:40 pm - 3:58 pm
SCL
-
STL
20h 18m1 stop
Delta Logo
3:42 pm - 7:15 am
STL
-
SCL
14h 33m1 stop
$829Delta
Fri, May 22 - Sun, Jun 14
Delta Logo
8:40 pm - 12:54 pm
SCL
-
STL
17h 14m1 stop
Delta Logo
3:42 pm - 7:15 am
STL
-
SCL
14h 33m1 stop
$835Delta
Fri, May 22 - Fri, Jun 12
LATAM Airlines Logo
7:45 am - 11:38 pm
SCL
-
STL
16h 53m2 stops
LATAM Airlines Logo
5:30 pm - 7:15 am
STL
-
SCL
12h 45m1 stop
$838LATAM Airlines
Sun, May 24 - Fri, Jun 12
United Airlines Logo
10:45 pm - 2:29 pm
SCL
-
STL
18h 44m2 stops
United Airlines Logo
6:55 pm - 8:50 am
STL
-
SCL
34h 55m2 stops
$850United Airlines
Wed, Feb 25 - Sun, Mar 1

Delta flights from Santiago to St. Louis

Our best Delta deals on Santiago to St. Louis flight tickets
Delta
May 20
SCL8:40 pmSantiago Arturo Merino Benitez
17h 14m
1 stop
STL12:54 pmLambert-St Louis
Jun 11
STL5:30 pmLambert-St Louis
12h 45m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$790
Find similar
Delta
May 22
SCL8:40 pmSantiago Arturo Merino Benitez
17h 14m
1 stop
STL12:54 pmLambert-St Louis
Jun 16
STL1:30 pmLambert-St Louis
15h 05m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
$810
Find similar
Delta
May 22
SCL8:40 pmSantiago Arturo Merino Benitez
20h 18m
1 stop
STL3:58 pmLambert-St Louis
Jun 14
STL3:42 pmLambert-St Louis
14h 33m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$829
Find similar

American Airlines flights from Santiago to St. Louis

Our best American Airlines deals on Santiago to St. Louis flight tickets
American Airlines
May 20
SCL8:50 pmSantiago Arturo Merino Benitez
27h 36m
2 stops
STL11:26 pmLambert-St Louis
Jun 14
STL5:25 amLambert-St Louis
24h 40m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
$968
Find similar
American Airlines
May 23
SCL8:50 pmSantiago Arturo Merino Benitez
43h 33m
2 stops
STL3:23 pmLambert-St Louis
Jun 12
STL10:35 amLambert-St Louis
19h 30m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
$988
Find similar
American Airlines
May 26
SCL8:50 pmSantiago Arturo Merino Benitez
14h 33m
1 stop
STL10:23 amLambert-St Louis
Jun 16
STL10:53 amLambert-St Louis
19h 12m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
$1,246
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 5/20

8:40 pm-12:54 pm

1 stop17h 14m

Lambert-St Louis

Thu 6/11

5:30 pm-7:15 am

1 stop12h 45m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 2/25

10:45 pm-3:38 pm

1 stop19h 53m

Lambert-St Louis

Sun 3/1

6:55 pm-8:50 am

2 stops34h 55m

$792

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 2/25

6:30 pm-11:02 am

2 stops19h 32m

Lambert-St Louis

Sun 3/1

10:13 am-2:05 pm

2 stops24h 52m

$804

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 5/22

8:40 pm-12:54 pm

1 stop17h 14m

Lambert-St Louis

Tue 6/16

1:30 pm-5:35 am

2 stops15h 05m

$810

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 5/21

7:05 am-11:38 pm

2 stops17h 33m

Lambert-St Louis

Sat 6/13

6:00 am-6:00 am

2 stops23h 00m

$818

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sun 5/24

8:30 am-10:45 am

3 stops27h 15m

Lambert-St Louis

Tue 6/16

11:51 am-6:00 am

2 stops17h 09m

$823

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 5/22

8:40 pm-3:58 pm

1 stop20h 18m

Lambert-St Louis

Sun 6/14

3:42 pm-7:15 am

1 stop14h 33m

$829

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 5/22

8:40 pm-12:54 pm

1 stop17h 14m

Lambert-St Louis

Fri 6/12

3:42 pm-7:15 am

1 stop14h 33m

$835

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sun 5/24

7:45 am-11:38 pm

2 stops16h 53m

Lambert-St Louis

Fri 6/12

5:30 pm-7:15 am

1 stop12h 45m

$838

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 2/25

10:45 pm-2:29 pm

2 stops18h 44m

Lambert-St Louis

Sun 3/1

6:55 pm-8:50 am

2 stops34h 55m

$850

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

16h 26m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 16h 26m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
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  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 16h 26m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santiago to St. Louis?

Best airlines flying from Santiago to St. Louis

Compare and see reviews for airlines that fly from Santiago to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $877Free CancellationRating
7.9
8,019 reviews
Search Delta flights
American AirlinesPriceFrom $948Free CancellationRating
7.2
11,072 reviews
Search American Airlines flights

  • How do I get Price Alerts for flights from Santiago to St. Louis?

    Search flight deals from Santiago to St. Louis. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Santiago to St. Louis with momondo?

    With “Price Forecast”, learn how soon you should book your flight in advance. Down to the day of week and time of day, our information can inform you on the ideal time to book to save on your travel. Our “Price Calendar” shows you at a quick glance when to book your travel for lower rates. By setting “Price Alerts” you can monitor changes in price and target the ideal time to book. Search for your trip destination by budget amount via our “Explore” feature. Whether you’re looking for ideas for your next travel adventure or cost-cutting tips, our “Discover” content is a great place to start.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
Fenton
Collinsville
St. Peters
Wentzville
Alton
Farmington
Clayton
Glencoe
Eureka
Festus
Edwardsville
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your St. Louis trip

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