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Cheap flights from Santiago to St. Louis from $359

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 8/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:50 pm - 10:45 am
SCL
-
STL
14h 55m
1 stop
American Airlines Logo
6:07 pm - 7:50 am
STL
-
SCL
11h 43m
1 stop
$875American Airlines
Fri, Sep 4 - Sun, Oct 11
American Airlines Logo
8:50 pm - 4:14 pm
SCL
-
STL
20h 24m
2 stops
American Airlines Logo
6:07 pm - 7:50 am
STL
-
SCL
11h 43m
1 stop
$880American Airlines
Fri, Sep 4 - Sun, Oct 11
Delta Logo
8:40 pm - 9:20 am
SCL
-
STL
13h 40m
1 stop
Delta Logo
9:15 am - 6:55 am
STL
-
SCL
20h 40m
2 stops
$932Delta
Fri, Aug 7 - Thu, Aug 13
LATAM Airlines Logo
8:40 pm - 11:56 am
SCL
-
STL
16h 16m
1 stop
LATAM Airlines Logo
6:00 am - 7:15 am
STL
-
SCL
24h 15m
1 stop
$940LATAM Airlines
Fri, Aug 7 - Thu, Aug 13
LATAM Airlines Logo
12:35 pm - 11:56 am
SCL
-
STL
24h 21m
2 stops
LATAM Airlines Logo
6:00 am - 1:35 pm
STL
-
SCL
30h 35m
2 stops
$949LATAM Airlines
Fri, Aug 7 - Thu, Aug 13
LATAM Airlines Logo
5:40 am - 11:58 pm
SCL
-
STL
19h 18m
2 stops
LATAM Airlines Logo
12:52 pm - 1:25 pm
STL
-
SCL
23h 33m
3 stops
$953LATAM Airlines
Fri, Aug 7 - Thu, Aug 13
LATAM Airlines Logo
4:15 am - 11:58 pm
SCL
-
STL
20h 43m
2 stops
LATAM Airlines Logo
11:00 am - 1:25 pm
STL
-
SCL
25h 25m
3 stops
$955LATAM Airlines
Fri, Aug 7 - Thu, Aug 13
Copa Airlines Logo
11:22 am - 12:03 pm
SCL
-
STL
25h 41m
2 stops
Copa Airlines Logo
8:00 am - 6:10 am
STL
-
SCL
20h 10m
2 stops
$959Copa Airlines
Fri, Sep 4 - Sun, Oct 11
Delta Logo
8:40 pm - 4:17 pm
SCL
-
STL
20h 37m
1 stop
Delta Logo
11:00 am - 7:15 am
STL
-
SCL
19h 15m
1 stop
$996Delta
Fri, Aug 7 - Thu, Aug 13
American Airlines Logo
8:50 pm - 4:14 pm
SCL
-
STL
20h 24m
2 stops
American Airlines Logo
11:21 am - 7:50 am
STL
-
SCL
18h 29m
2 stops
$1,009American Airlines
Fri, Sep 4 - Sun, Oct 11

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Delta flights from Santiago to St. Louis

Our best Delta deals on Santiago to St. Louis flight tickets
Delta
Aug 7
SCL8:40 pmSantiago Arturo Merino Benitez
13h 40m
1 stop
STL9:20 amLambert-St Louis
Aug 13
STL9:15 amLambert-St Louis
20h 40m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
$932
Delta
Aug 7
SCL8:40 pmSantiago Arturo Merino Benitez
20h 37m
1 stop
STL4:17 pmLambert-St Louis
Aug 13
STL11:00 amLambert-St Louis
19h 15m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$996
Delta
Jul 21
SCL10:25 amSantiago Arturo Merino Benitez
26h 52m
2 stops
STL12:17 pmLambert-St Louis
Jul 28
STL7:08 amLambert-St Louis
21h 52m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
$1,259

LATAM Airlines flights from Santiago to St. Louis

Our best LATAM Airlines deals on Santiago to St. Louis flight tickets
LATAM Airlines
Aug 7
SCL8:40 pmSantiago Arturo Merino Benitez
16h 16m
1 stop
STL11:56 amLambert-St Louis
Aug 13
STL6:00 amLambert-St Louis
24h 15m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$940
LATAM Airlines
Aug 7
SCL12:35 pmSantiago Arturo Merino Benitez
24h 21m
2 stops
STL11:56 amLambert-St Louis
Aug 13
STL6:00 amLambert-St Louis
30h 35m
2 stops
SCL1:35 pmSantiago Arturo Merino Benitez
$949
LATAM Airlines
Aug 7
SCL5:40 amSantiago Arturo Merino Benitez
19h 18m
2 stops
STL11:58 pmLambert-St Louis
Aug 13
STL12:52 pmLambert-St Louis
23h 33m
3 stops
SCL1:25 pmSantiago Arturo Merino Benitez
$953

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 16, 2026.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 9/4

8:50 pm-10:45 am

1 stop14h 55m

Lambert-St Louis

Sun 10/11

6:07 pm-7:50 am

1 stop11h 43m

$875

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 9/4

8:50 pm-4:14 pm

2 stops20h 24m

Lambert-St Louis

Sun 10/11

6:07 pm-7:50 am

1 stop11h 43m

$880

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 8/7

8:40 pm-9:20 am

1 stop13h 40m

Lambert-St Louis

Thu 8/13

9:15 am-6:55 am

2 stops20h 40m

$932

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 8/7

8:40 pm-11:56 am

1 stop16h 16m

Lambert-St Louis

Thu 8/13

6:00 am-7:15 am

1 stop24h 15m

$940

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 8/7

12:35 pm-11:56 am

2 stops24h 21m

Lambert-St Louis

Thu 8/13

6:00 am-1:35 pm

2 stops30h 35m

$949

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 8/7

5:40 am-11:58 pm

2 stops19h 18m

Lambert-St Louis

Thu 8/13

12:52 pm-1:25 pm

3 stops23h 33m

$953

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 8/7

4:15 am-11:58 pm

2 stops20h 43m

Lambert-St Louis

Thu 8/13

11:00 am-1:25 pm

3 stops25h 25m

$955

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 9/4

11:22 am-12:03 pm

2 stops25h 41m

Lambert-St Louis

Sun 10/11

8:00 am-6:10 am

2 stops20h 10m

$959

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 8/7

8:40 pm-4:17 pm

1 stop20h 37m

Lambert-St Louis

Thu 8/13

11:00 am-7:15 am

1 stop19h 15m

$996

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 9/4

8:50 pm-4:14 pm

2 stops20h 24m

Lambert-St Louis

Sun 10/11

11:21 am-7:50 am

2 stops18h 29m

$1,009

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Santiago to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. The month of December is another great option to travel to St. Louis, with average flight prices from Santiago averaging around $795.

Can stopping save me money on Santiago to St. Louis flights?

You could potentially save up to 27% on your flight if you consider stops on a Santiago to St. Louis flight.

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

25h 41m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 25h 41m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
Search flight deals

Frequently asked questions about flying from Santiago to St. Louis

  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 25h 41m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
Collinsville
Florissant
St. Peters
Maryland Heights
O'Fallon
Alton
Farmington
Wentzville
Clayton
Fenton
Festus
Eureka
Edwardsville
Litchfield
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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