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Cheap flights from Santiago to St. Louis from $384

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 8/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santiago to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
2:22 am - 8:39 am
SCL
-
STL
31h 17m
2 stops
Copa Airlines Logo
7:05 pm - 1:50 am
STL
-
SCL
29h 45m
2 stops
$1,010Copa Airlines
Tue, Jun 2 - Wed, Jul 15
Air Canada Logo
8:55 pm - 4:30 pm
SCL
-
STL
21h 35m
1 stop
Air Canada Logo
4:15 pm - 11:15 am
STL
-
SCL
16h 00m
1 stop
$1,031Air Canada
Sat, Oct 31 - Wed, Nov 4
LATAM Airlines Logo
8:40 pm - 9:43 am
SCL
-
STL
14h 03m
1 stop
LATAM Airlines Logo
6:00 am - 7:15 am
STL
-
SCL
24h 15m
1 stop
$1,071LATAM Airlines
Thu, Jul 9 - Thu, Jul 16
American Airlines Logo
9:00 pm - 10:24 am
SCL
-
STL
14h 24m
1 stop
American Airlines Logo
11:35 am - 6:50 am
STL
-
SCL
18h 15m
1 stop
$1,073American Airlines
Wed, Jul 15 - Wed, Aug 5
LATAM Airlines Logo
11:05 pm - 8:19 am
SCL
-
STL
34h 14m
2 stops
LATAM Airlines Logo
6:00 am - 6:00 am
STL
-
SCL
23h 00m
2 stops
$1,074LATAM Airlines
Wed, Jul 15 - Wed, Aug 5
LATAM Airlines Logo
8:40 pm - 9:43 am
SCL
-
STL
14h 03m
1 stop
LATAM Airlines Logo
6:00 am - 6:00 am
STL
-
SCL
23h 00m
2 stops
$1,080LATAM Airlines
Thu, Jul 9 - Thu, Jul 16
LATAM Airlines Logo
8:40 pm - 9:43 am
SCL
-
STL
14h 03m
1 stop
LATAM Airlines Logo
6:00 am - 6:00 am
STL
-
SCL
23h 00m
2 stops
$1,082LATAM Airlines
Wed, Jul 15 - Wed, Aug 5
Delta Logo
10:55 pm - 5:19 pm
SCL
-
STL
19h 24m
2 stops
Delta Logo
9:24 am - 6:55 am
STL
-
SCL
20h 31m
2 stops
$1,085Delta
Thu, Jul 9 - Thu, Jul 16
Delta Logo
11:00 pm - 5:53 pm
SCL
-
STL
19h 53m
2 stops
Delta Logo
9:17 am - 6:00 am
STL
-
SCL
19h 43m
2 stops
$1,086Delta
Wed, Jul 15 - Wed, Aug 5
Delta Logo
11:00 pm - 2:38 pm
SCL
-
STL
17h 38m
2 stops
Delta Logo
3:42 pm - 2:05 pm
STL
-
SCL
20h 23m
2 stops
$1,101Delta
Sat, Sep 12 - Sat, Sep 26

Air Canada flights from Santiago to St. Louis

Our best Air Canada deals on Santiago to St. Louis flight tickets
Air Canada
Oct 31
SCL8:55 pmSantiago Arturo Merino Benitez
21h 35m
1 stop
STL4:30 pmLambert-St Louis
Nov 4
STL4:15 pmLambert-St Louis
16h 00m
1 stop
SCL11:15 amSantiago Arturo Merino Benitez
$1,031
Air Canada
Oct 31
SCL8:55 pmSantiago Arturo Merino Benitez
21h 35m
1 stop
STL4:30 pmLambert-St Louis
Nov 4
STL4:15 pmLambert-St Louis
20h 05m
2 stops
SCL3:20 pmSantiago Arturo Merino Benitez
$1,134

American Airlines flights from Santiago to St. Louis

Our best American Airlines deals on Santiago to St. Louis flight tickets
American Airlines
Jul 15
SCL9:00 pmSantiago Arturo Merino Benitez
14h 24m
1 stop
STL10:24 amLambert-St Louis
Aug 5
STL11:35 amLambert-St Louis
18h 15m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
$1,073
American Airlines
Jul 2
SCL9:00 pmSantiago Arturo Merino Benitez
26h 53m
1 stop
STL10:53 pmLambert-St Louis
Jul 9
STL5:18 amLambert-St Louis
24h 42m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$1,147
American Airlines
Jul 2
SCL9:00 pmSantiago Arturo Merino Benitez
21h 08m
2 stops
STL5:08 pmLambert-St Louis
Jul 9
STL9:24 amLambert-St Louis
20h 36m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
$1,152

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 19, 2026.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 6/2

2:22 am-8:39 am

2 stops31h 17m

Lambert-St Louis

Wed 7/15

7:05 pm-1:50 am

2 stops29h 45m

$1,010

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sat 10/31

8:55 pm-4:30 pm

1 stop21h 35m

Lambert-St Louis

Wed 11/4

4:15 pm-11:15 am

1 stop16h 00m

$1,031

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 7/9

8:40 pm-9:43 am

1 stop14h 03m

Lambert-St Louis

Thu 7/16

6:00 am-7:15 am

1 stop24h 15m

$1,071
Quickest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 7/15

9:00 pm-10:24 am

1 stop14h 24m

Lambert-St Louis

Wed 8/5

11:35 am-6:50 am

1 stop18h 15m

$1,073

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 7/15

11:05 pm-8:19 am

2 stops34h 14m

Lambert-St Louis

Wed 8/5

6:00 am-6:00 am

2 stops23h 00m

$1,074

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 7/9

8:40 pm-9:43 am

1 stop14h 03m

Lambert-St Louis

Thu 7/16

6:00 am-6:00 am

2 stops23h 00m

$1,080

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 7/15

8:40 pm-9:43 am

1 stop14h 03m

Lambert-St Louis

Wed 8/5

6:00 am-6:00 am

2 stops23h 00m

$1,082

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 7/9

10:55 pm-5:19 pm

2 stops19h 24m

Lambert-St Louis

Thu 7/16

9:24 am-6:55 am

2 stops20h 31m

$1,085

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 7/15

11:00 pm-5:53 pm

2 stops19h 53m

Lambert-St Louis

Wed 8/5

9:17 am-6:00 am

2 stops19h 43m

$1,086

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sat 9/12

11:00 pm-2:38 pm

2 stops17h 38m

Lambert-St Louis

Sat 9/26

3:42 pm-2:05 pm

2 stops20h 23m

$1,101

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, December is the cheapest month to fly from Santiago to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $795. The month of March is another great option to travel to St. Louis, with average flight prices from Santiago averaging around $835.

Can stopping save me money on Santiago to St. Louis flights?

You could potentially save up to 34% on your flight if you consider stops on a Santiago to St. Louis flight.

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

17h 38m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 17h 38m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
Search flight deals

Frequently asked questions about flying from Santiago to St. Louis

  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 17h 38m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
Florissant
O'Fallon
St. Peters
Collinsville
Alton
Wentzville
Fenton
Farmington
Festus
Eureka
Clayton
Litchfield
Edwardsville
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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