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Cheap flights from Santiago to St. Louis from $461

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 8/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santiago to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:09 am - 11:49 pm
SCL
-
STL
20h 40m
2 stops
Multiple Airlines Logo
4:17 pm - 1:35 pm
STL
-
SCL
44h 18m
2 stops
$870Multiple Airlines
Tue, Jun 16 - Tue, Jun 23
Multiple Airlines Logo
12:01 am - 11:49 pm
SCL
-
STL
24h 48m
2 stops
Multiple Airlines Logo
4:17 pm - 6:55 am
STL
-
SCL
37h 38m
3 stops
$884Multiple Airlines
Mon, Jun 15 - Tue, Jun 23
Multiple Airlines Logo
5:00 am - 11:49 pm
SCL
-
STL
19h 49m
2 stops
Multiple Airlines Logo
4:17 pm - 1:35 pm
STL
-
SCL
44h 18m
2 stops
$916Multiple Airlines
Wed, Jun 17 - Wed, Jun 24
Multiple Airlines Logo
12:25 am - 11:49 pm
SCL
-
STL
24h 24m
2 stops
Multiple Airlines Logo
4:17 pm - 6:55 am
STL
-
SCL
37h 38m
3 stops
$921Multiple Airlines
Tue, Jun 16 - Wed, Jun 24
Multiple Airlines Logo
12:43 am - 7:23 pm
SCL
-
STL
43h 40m
3 stops
Multiple Airlines Logo
4:09 pm - 6:55 am
STL
-
SCL
37h 46m
3 stops
$929Multiple Airlines
Tue, Jul 14 - Wed, Aug 5
Multiple Airlines Logo
12:25 am - 2:06 pm
SCL
-
STL
62h 41m
3 stops
Multiple Airlines Logo
4:17 pm - 6:55 am
STL
-
SCL
37h 38m
3 stops
$956Multiple Airlines
Tue, Jun 16 - Wed, Jun 24
Multiple Airlines Logo
4:30 pm - 11:49 pm
SCL
-
STL
32h 19m
2 stops
Multiple Airlines Logo
3:34 pm - 1:35 pm
STL
-
SCL
45h 01m
3 stops
$973Multiple Airlines
Wed, Jul 1 - Wed, Jul 8
Multiple Airlines Logo
2:22 am - 7:23 pm
SCL
-
STL
66h 01m
3 stops
Multiple Airlines Logo
4:17 pm - 1:35 pm
STL
-
SCL
44h 18m
2 stops
$1,004Multiple Airlines
Sat, Jun 13 - Sun, Jun 21
Multiple Airlines Logo
11:17 am - 6:51 pm
SCL
-
STL
56h 34m
3 stops
Multiple Airlines Logo
4:17 pm - 6:00 am
STL
-
SCL
36h 43m
2 stops
$1,008Multiple Airlines
Sun, Jun 14 - Sun, Jun 21
Multiple Airlines Logo
4:30 pm - 11:59 pm
SCL
-
STL
32h 29m
2 stops
Multiple Airlines Logo
7:03 pm - 1:35 pm
STL
-
SCL
41h 32m
3 stops
$1,012Multiple Airlines
Wed, Jul 15 - Wed, Aug 5

American Airlines flights from Santiago to St. Louis

Our best American Airlines deals on Santiago to St. Louis flight tickets
American Airlines
Jul 15
SCL9:00 pmSantiago Arturo Merino Benitez
26h 53m
1 stop
STL10:53 pmLambert-St Louis
Aug 5
STL11:35 amLambert-St Louis
18h 15m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
$1,026
American Airlines
Jul 15
SCL9:00 pmSantiago Arturo Merino Benitez
26h 53m
1 stop
STL10:53 pmLambert-St Louis
Aug 5
STL10:22 amLambert-St Louis
19h 28m
2 stops
SCL6:50 amSantiago Arturo Merino Benitez
$1,031
American Airlines
Jul 15
SCL9:00 pmSantiago Arturo Merino Benitez
26h 53m
1 stop
STL10:53 pmLambert-St Louis
Aug 5
STL5:00 amLambert-St Louis
24h 50m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
$1,033

United Airlines flights from Santiago to St. Louis

Our best United Airlines deals on Santiago to St. Louis flight tickets
United Airlines
Oct 27
SCL9:45 pmSantiago Arturo Merino Benitez
22h 53m
1 stop
STL6:38 pmLambert-St Louis
Oct 31
STL8:50 amLambert-St Louis
21h 00m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
$1,220
United Airlines
Oct 27
SCL9:45 pmSantiago Arturo Merino Benitez
20h 50m
1 stop
STL4:35 pmLambert-St Louis
Oct 31
STL1:27 pmLambert-St Louis
16h 23m
2 stops
SCL7:50 amSantiago Arturo Merino Benitez
$1,225

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 6/16

4:09 am-11:49 pm

2 stops20h 40m

Lambert-St Louis

Tue 6/23

4:17 pm-1:35 pm

2 stops44h 18m

$870

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 6/15

12:01 am-11:49 pm

2 stops24h 48m

Lambert-St Louis

Tue 6/23

4:17 pm-6:55 am

3 stops37h 38m

$884

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 6/17

5:00 am-11:49 pm

2 stops19h 49m

Lambert-St Louis

Wed 6/24

4:17 pm-1:35 pm

2 stops44h 18m

$916
Quickest round-trip

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 6/16

12:25 am-11:49 pm

2 stops24h 24m

Lambert-St Louis

Wed 6/24

4:17 pm-6:55 am

3 stops37h 38m

$921

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 7/14

12:43 am-7:23 pm

3 stops43h 40m

Lambert-St Louis

Wed 8/5

4:09 pm-6:55 am

3 stops37h 46m

$929

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 6/16

12:25 am-2:06 pm

3 stops62h 41m

Lambert-St Louis

Wed 6/24

4:17 pm-6:55 am

3 stops37h 38m

$956

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 7/1

4:30 pm-11:49 pm

2 stops32h 19m

Lambert-St Louis

Wed 7/8

3:34 pm-1:35 pm

3 stops45h 01m

$973

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sat 6/13

2:22 am-7:23 pm

3 stops66h 01m

Lambert-St Louis

Sun 6/21

4:17 pm-1:35 pm

2 stops44h 18m

$1,004

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sun 6/14

11:17 am-6:51 pm

3 stops56h 34m

Lambert-St Louis

Sun 6/21

4:17 pm-6:00 am

2 stops36h 43m

$1,008

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 7/15

4:30 pm-11:59 pm

2 stops32h 29m

Lambert-St Louis

Wed 8/5

7:03 pm-1:35 pm

3 stops41h 32m

$1,012

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, December is the cheapest month to fly from Santiago to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $795. The month of March is another great option to travel to St. Louis, with average flight prices from Santiago averaging around $835.

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

14h 04m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 14h 04m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
Search flight deals

Frequently asked questions about flying from Santiago to St. Louis

  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 14h 04m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santiago to St. Louis?

Best airlines flying from Santiago to St. Louis

Compare and see reviews for airlines that fly from Santiago to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $542Free CancellationRating
7.9
8,460 reviews
Search Delta flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
St. Peters
Collinsville
Wentzville
Alton
Fenton
Farmington
Festus
Clayton
Eureka
Litchfield
Edwardsville
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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