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Cheap flights from Santiago to St. Louis from $377

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
8:50 am - 11:54 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
17h 04m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
LATAM Airlines Logo
7:20 pm - 2:45 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
17h 25m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$951LATAM Airlines
Tue, Oct 6 - Tue, Oct 13
LATAM Airlines Logo
8:50 am - 11:54 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
17h 04m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
LATAM Airlines Logo
5:35 pm - 8:15 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
12h 40m1 stop Atlanta Hartsfield-Jackson
$951LATAM Airlines
Tue, Oct 6 - Tue, Oct 13
LATAM Airlines Logo
8:40 pm - 9:09 amSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
14h 29m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
5:35 pm - 8:15 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
12h 40m1 stop Atlanta Hartsfield-Jackson
$951LATAM Airlines
Tue, Oct 6 - Tue, Oct 13
Delta Logo
12:35 am - 4:17 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
16h 42m2 stops Miami Atlanta Hartsfield-Jackson
Delta Logo
10:40 am - 7:00 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
18h 20m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
$966Delta
Wed, Sep 2 - Wed, Sep 9
Delta Logo
8:40 pm - 4:17 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
20h 37m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:05 am - 8:15 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
23h 10m1 stop Atlanta Hartsfield-Jackson
$966Delta
Thu, Sep 3 - Wed, Sep 9
Delta Logo
8:40 pm - 11:46 amSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
16h 06m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:05 am - 5:40 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
20h 35m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$966Delta
Thu, Sep 3 - Wed, Sep 9
LATAM Airlines Logo
11:10 pm - 9:17 amSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
13h 07m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:00 am - 7:40 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
22h 40m1 stop Atlanta Hartsfield-Jackson
$975LATAM Airlines
Thu, Nov 5 - Mon, Nov 9
LATAM Airlines Logo
12:48 am - 4:32 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
18h 44m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson
LATAM Airlines Logo
2:31 pm - 7:40 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
14h 09m1 stop Atlanta Hartsfield-Jackson
$975LATAM Airlines
Wed, Nov 18 - Mon, Nov 23
LATAM Airlines Logo
12:48 am - 4:28 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
18h 40m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson
LATAM Airlines Logo
5:37 pm - 3:00 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
18h 23m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$975LATAM Airlines
Wed, Nov 4 - Mon, Nov 9
LATAM Airlines Logo
8:25 pm - 10:51 amSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
17h 26m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
LATAM Airlines Logo
5:37 pm - 3:00 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
18h 23m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$975LATAM Airlines
Thu, Nov 5 - Mon, Nov 9

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LATAM Airlines flights from Santiago to St. Louis

Our best LATAM Airlines deals on Santiago to St. Louis flight tickets
LATAM Airlines
Oct 6
SCL8:50 amSantiago Arturo Merino Benitez
17h 04m
2 stops
STL11:54 pmLambert-St Louis
Oct 13
STL7:20 pmLambert-St Louis
17h 25m
2 stops
SCL2:45 pmSantiago Arturo Merino Benitez
$951
LATAM Airlines
Sep 3
SCL6:45 pmSantiago Arturo Merino Benitez
18h 01m
2 stops
STL11:46 amLambert-St Louis
Sep 9
STL10:40 amLambert-St Louis
23h 09m
3 stops
SCL11:49 amSantiago Arturo Merino Benitez
$978
LATAM Airlines
Sep 17
SCL8:40 pmSantiago Arturo Merino Benitez
16h 15m
1 stop
STL10:55 amLambert-St Louis
Sep 20
STL6:00 amLambert-St Louis
24h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$1,039

Delta flights from Santiago to St. Louis

Our best Delta deals on Santiago to St. Louis flight tickets
Delta
Sep 3
SCL8:40 pmSantiago Arturo Merino Benitez
16h 06m
1 stop
STL11:46 amLambert-St Louis
Sep 9
STL7:05 amLambert-St Louis
20h 35m
2 stops
SCL5:40 amSantiago Arturo Merino Benitez
$966
Delta
Sep 17
SCL11:55 pmSantiago Arturo Merino Benitez
22h 03m
2 stops
STL7:58 pmLambert-St Louis
Sep 20
STL7:00 amLambert-St Louis
23h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$1,054

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2026.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Tue 10/6

8:50 am-11:54 pm

2 stops17h 04m

Lambert-St Louis

Tue 10/13

7:20 pm-2:45 pm

2 stops17h 25m

$951

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Tue 10/6

8:50 am-11:54 pm

2 stops17h 04m

Lambert-St Louis

Tue 10/13

5:35 pm-8:15 am

1 stop12h 40m

$951
Quickest round-trip

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Tue 10/6

8:40 pm-9:09 am

1 stop14h 29m

Lambert-St Louis

Tue 10/13

5:35 pm-8:15 am

1 stop12h 40m

$951

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Wed 9/2

12:35 am-4:17 pm

2 stops16h 42m

Lambert-St Louis

Wed 9/9

10:40 am-7:00 am

2 stops18h 20m

$966

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Thu 9/3

8:40 pm-4:17 pm

1 stop20h 37m

Lambert-St Louis

Wed 9/9

7:05 am-8:15 am

1 stop23h 10m

$966

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Thu 9/3

8:40 pm-11:46 am

1 stop16h 06m

Lambert-St Louis

Wed 9/9

7:05 am-5:40 am

2 stops20h 35m

$966

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Thu 11/5

11:10 pm-9:17 am

1 stop13h 07m

Lambert-St Louis

Mon 11/9

6:00 am-7:40 am

1 stop22h 40m

$975

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Wed 11/18

12:48 am-4:32 pm

2 stops18h 44m

Lambert-St Louis

Mon 11/23

2:31 pm-7:40 am

1 stop14h 09m

$975

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Wed 11/4

12:48 am-4:28 pm

2 stops18h 40m

Lambert-St Louis

Mon 11/9

5:37 pm-3:00 pm

2 stops18h 23m

$975

SantiagoSt. Louis

SCL Santiago Arturo Merino Benitez - STL Lambert-St Louis

SCLSTL

Santiago Arturo Merino Benitez

Thu 11/5

8:25 pm-10:51 am

2 stops17h 26m

Lambert-St Louis

Mon 11/9

5:37 pm-3:00 pm

2 stops18h 23m

$975

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Santiago to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $674. The month of December is another great option to travel to St. Louis, with average flight prices from Santiago averaging around $795.

Can stopping save me money on Santiago to St. Louis flights?

You could potentially save up to 22% on your flight if you consider stops on a Santiago to St. Louis flight.

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Fastest flight time

21h 01m

Direct flights

None
The fastest flight from Santiago to St. Louis takes 21h 01m
There are no direct flights from Santiago to St. Louis. There are no popular flight routes from Santiago to St. Louis.
Search flight deals

Frequently asked questions about flying from Santiago to St. Louis

  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 21h 01m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
St. Peters
Maryland Heights
Collinsville
Florissant
Alton
O'Fallon
Farmington
Clayton
Fenton
Festus
Wentzville
Eureka
Edwardsville
Litchfield
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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