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Cheap flights from Santiago to St. Louis from $775

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santiago to St. Louis (SCL-STL)

Cheap round-trip flights

Delta Logo
9:40 pm - 2:35 pmSCL-STL
18h 55m1 stop
Delta Logo
11:21 am - 4:30 amSTL-SCL
15h 09m2 stops
$775Delta
Find Deal
Wed, Oct 1 - Wed, Oct 8
LATAM Airlines Logo
12:25 am - 10:00 pmSCL-STL
23h 35m2 stops
LATAM Airlines Logo
1:30 pm - 7:00 amSTL-SCL
15h 30m1 stop
$781LATAM Airlines
Find Deal
Tue, Sep 30 - Wed, Oct 8
Delta Logo
11:40 pm - 4:40 pmSCL-STL
20h 00m1 stop
Delta Logo
11:51 am - 7:00 amSTL-SCL
16h 09m1 stop
$784Delta
Find Deal
Thu, Nov 13 - Mon, Nov 17
Delta Logo
12:55 am - 6:02 pmSCL-STL
20h 07m2 stops
Delta Logo
1:30 pm - 7:00 amSTL-SCL
14h 30m2 stops
$788Delta
Find Deal
Wed, Nov 12 - Mon, Nov 17
LATAM Airlines Logo
9:40 pm - 8:44 amSCL-STL
13h 04m1 stop
LATAM Airlines Logo
5:11 pm - 7:00 amSTL-SCL
11h 49m1 stop
$861LATAM Airlines
Find Deal
Fri, Sep 12 - Sat, Sep 20
LATAM Airlines Logo
11:55 pm - 7:05 pmSCL-STL
21h 10m2 stops
LATAM Airlines Logo
10:15 am - 6:45 amSTL-SCL
18h 30m2 stops
$884LATAM Airlines
Find Deal
Fri, Sep 12 - Sat, Sep 20
LATAM Airlines Logo
12:25 am - 5:47 pmSCL-STL
19h 22m2 stops
LATAM Airlines Logo
5:11 pm - 7:00 amSTL-SCL
11h 49m1 stop
$1,407LATAM Airlines
Find Deal
Thu, Sep 11 - Sat, Sep 20
LATAM Airlines Logo
3:30 pm - 9:59 amSCL-STL
20h 29m3 stops
LATAM Airlines Logo
11:21 am - 4:30 amSTL-SCL
15h 09m2 stops
$1,639LATAM Airlines
Find Deal
Wed, Oct 1 - Wed, Oct 8
Logo
12:55 am - 7:38 pmSCL-STL
20h 43m2 stops
Logo
9:15 am - 8:36 pmSTL-SCL
33h 21m3 stops
$5,106
Find Deal
Tue, Sep 30 - Wed, Oct 8

Delta flights from Santiago to St. Louis

Our best Delta deals on Santiago to St. Louis flight tickets
Delta
Oct 1
SCL9:40 pmSantiago Arturo Merino Benitez
18h 55m
1 stop
STL2:35 pmLambert-St Louis
Oct 8
STL11:21 amLambert-St Louis
15h 09m
2 stops
SCL4:30 amSantiago Arturo Merino Benitez
$775
Find similar
Delta
Nov 13
SCL11:40 pmSantiago Arturo Merino Benitez
20h 00m
1 stop
STL4:40 pmLambert-St Louis
Nov 17
STL11:51 amLambert-St Louis
16h 09m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$784
Find similar
Delta
Nov 12
SCL12:55 amSantiago Arturo Merino Benitez
20h 07m
2 stops
STL6:02 pmLambert-St Louis
Nov 17
STL1:30 pmLambert-St Louis
14h 30m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
$788
Find similar

LATAM Airlines flights from Santiago to St. Louis

Our best LATAM Airlines deals on Santiago to St. Louis flight tickets
LATAM Airlines
Sep 30
SCL12:25 amSantiago Arturo Merino Benitez
23h 35m
2 stops
STL10:00 pmLambert-St Louis
Oct 8
STL1:30 pmLambert-St Louis
15h 30m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$781
Find similar
LATAM Airlines
Sep 12
SCL9:40 pmSantiago Arturo Merino Benitez
13h 04m
1 stop
STL8:44 amLambert-St Louis
Sep 20
STL5:11 pmLambert-St Louis
11h 49m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$861
Find similar
LATAM Airlines
Sep 12
SCL11:55 pmSantiago Arturo Merino Benitez
21h 10m
2 stops
STL7:05 pmLambert-St Louis
Sep 20
STL10:15 amLambert-St Louis
18h 30m
2 stops
SCL6:45 amSantiago Arturo Merino Benitez
$884
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 10/1

9:40 pm-2:35 pm

1 stop18h 55m

Lambert-St Louis

Wed 10/8

11:21 am-4:30 am

2 stops15h 09m

$775

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 9/30

12:25 am-10:00 pm

2 stops23h 35m

Lambert-St Louis

Wed 10/8

1:30 pm-7:00 am

1 stop15h 30m

$781

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 11/13

11:40 pm-4:40 pm

1 stop20h 00m

Lambert-St Louis

Mon 11/17

11:51 am-7:00 am

1 stop16h 09m

$784

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 11/12

12:55 am-6:02 pm

2 stops20h 07m

Lambert-St Louis

Mon 11/17

1:30 pm-7:00 am

2 stops14h 30m

$788

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 9/12

9:40 pm-8:44 am

1 stop13h 04m

Lambert-St Louis

Sat 9/20

5:11 pm-7:00 am

1 stop11h 49m

$861

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 9/12

11:55 pm-7:05 pm

2 stops21h 10m

Lambert-St Louis

Sat 9/20

10:15 am-6:45 am

2 stops18h 30m

$884

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 9/11

12:25 am-5:47 pm

2 stops19h 22m

Lambert-St Louis

Sat 9/20

5:11 pm-7:00 am

1 stop11h 49m

$1,407

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 10/1

3:30 pm-9:59 am

3 stops20h 29m

Lambert-St Louis

Wed 10/8

11:21 am-4:30 am

2 stops15h 09m

$1,639

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 9/30

12:55 am-7:38 pm

2 stops20h 43m

Lambert-St Louis

Wed 10/8

9:15 am-8:36 pm

3 stops33h 21m

$5,106

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to St. Louis from

How to get the cheapest flight ticket from Santiago to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Tuesday when prices can be found for as low as $780. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $1,051. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

When to book flights from Santiago to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to St. Louis (SCL to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to St. Louis

Best Price Found

$775

Fastest flight time

13h 04m

Direct flights

None

Airports in St. Louis

1 airport
The best flight deal from Santiago to St. Louis found on momondo in the last 72 hours is $775
The fastest flight from Santiago to St. Louis takes 13h 04m
There are no direct flights from Santiago to St. Louis. Popular non-direct route for this connection is Santiago Arturo Merino Benitez Airport - Lambert-St Louis Airport.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
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  • How far is Santiago Arturo Merino Benitez to Lambert-St Louis by plane?

    Santiago Arturo Merino Benitez and Lambert-St Louis are 5131.6 mi apart from one another. By plane, this route typically takes 13h 04m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santiago to St. Louis?

Best airlines flying from Santiago to St. Louis

Compare and see reviews for airlines that fly from Santiago to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $782Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $925Free CancellationRating
8.0
7,981 reviews
Search Delta flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
Maryland Heights
Florissant
O'Fallon
Fenton
Wentzville
Collinsville
Alton
St. Peters
Farmington
Festus
Glencoe
Eureka
Clayton
Edwardsville
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Santiago.

I’m not ready to book a flight from Santiago to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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