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Cheap flights from Santa Ana to Roanoke from $353

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Roanoke departing on 4/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana to Roanoke

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:01 pm - 10:59 pm
SNA
-
ROA
7h 58m
1 stop
American Airlines Logo
7:00 am - 1:39 pm
ROA
-
SNA
9h 39m
1 stop
$359American Airlines
Wed, Jul 1 - Tue, Jul 7
American Airlines Logo
1:36 pm - 12:10 am
SNA
-
ROA
7h 34m
1 stop
American Airlines Logo
7:28 am - 2:21 pm
ROA
-
SNA
9h 53m
1 stop
$370American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
1:36 pm - 12:10 am
SNA
-
ROA
7h 34m
1 stop
American Airlines Logo
7:00 am - 2:21 pm
ROA
-
SNA
10h 21m
2 stops
$375American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
12:01 pm - 10:59 pm
SNA
-
ROA
7h 58m
1 stop
American Airlines Logo
7:00 am - 12:05 pm
ROA
-
SNA
8h 05m
1 stop
$417American Airlines
Wed, Jul 1 - Tue, Jul 7
United Airlines Logo
10:50 am - 11:44 pm
SNA
-
ROA
9h 54m
2 stops
United Airlines Logo
6:45 am - 2:22 pm
ROA
-
SNA
10h 37m
2 stops
$424United Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
1:36 pm - 12:10 am
SNA
-
ROA
7h 34m
1 stop
American Airlines Logo
7:28 am - 2:21 pm
ROA
-
SNA
9h 53m
1 stop
$487American Airlines
Fri, Apr 10 - Sun, Apr 12
American Airlines Logo
12:01 pm - 10:59 pm
SNA
-
ROA
7h 58m
1 stop
American Airlines Logo
8:00 am - 3:38 pm
ROA
-
SNA
10h 38m
2 stops
$538American Airlines
Wed, Jul 1 - Tue, Jul 7
American Airlines Logo
1:36 pm - 12:10 am
SNA
-
ROA
7h 34m
1 stop
American Airlines Logo
5:00 am - 12:38 pm
ROA
-
SNA
10h 38m
2 stops
$553American Airlines
Fri, Apr 10 - Sun, Apr 12
American Airlines Logo
6:45 am - 7:33 pm
SNA
-
ROA
9h 48m
2 stops
American Airlines Logo
7:00 am - 1:39 pm
ROA
-
SNA
9h 39m
1 stop
$563American Airlines
Wed, Jul 1 - Tue, Jul 7
United Airlines Logo
6:20 pm - 10:12 am
SNA
-
ROA
12h 52m
2 stops
United Airlines Logo
6:40 am - 9:05 am
ROA
-
SNA
29h 25m
2 stops
$568United Airlines
Wed, Jul 1 - Tue, Jul 7

United Airlines flights from Santa Ana to Roanoke

Our best United Airlines deals on Santa Ana to Roanoke flight tickets
United Airlines
Apr 29
SNA10:50 amSanta Ana J. Wayne/Orange Cnty
9h 54m
2 stops
ROA11:44 pmRoanoke
May 2
ROA6:45 amRoanoke
10h 37m
2 stops
SNA2:22 pmSanta Ana J. Wayne/Orange Cnty
$424
United Airlines
Jul 1
SNA6:20 pmSanta Ana J. Wayne/Orange Cnty
12h 52m
2 stops
ROA10:12 amRoanoke
Jul 7
ROA6:40 amRoanoke
29h 25m
2 stops
SNA9:05 amSanta Ana J. Wayne/Orange Cnty
$568
United Airlines
Jul 1
SNA6:26 pmSanta Ana J. Wayne/Orange Cnty
12h 16m
2 stops
ROA9:42 amRoanoke
Jul 7
ROA6:40 amRoanoke
29h 25m
2 stops
SNA9:05 amSanta Ana J. Wayne/Orange Cnty
$611

Delta flights from Santa Ana to Roanoke

Our best Delta deals on Santa Ana to Roanoke flight tickets
Delta
Mar 11
SNA11:56 amSanta Ana J. Wayne/Orange Cnty
9h 08m
1 stop
ROA12:04 amRoanoke
Mar 15
ROA6:00 amRoanoke
8h 24m
1 stop
SNA11:24 amSanta Ana J. Wayne/Orange Cnty
$611
Delta
Mar 11
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
13h 34m
2 stops
ROA12:04 amRoanoke
Mar 15
ROA6:00 amRoanoke
8h 24m
1 stop
SNA11:24 amSanta Ana J. Wayne/Orange Cnty
$622
Delta
Jun 8
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 49m
1 stop
ROA11:49 pmRoanoke
Jun 12
ROA7:50 pmRoanoke
25h 47m
1 stop
SNA6:37 pmSanta Ana J. Wayne/Orange Cnty
$690

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Santa Ana to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 7/1

12:01 pm-10:59 pm

1 stop7h 58m

Roanoke

Tue 7/7

7:00 am-1:39 pm

1 stop9h 39m

$359

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 4/29

1:36 pm-12:10 am

1 stop7h 34m

Roanoke

Sat 5/2

7:28 am-2:21 pm

1 stop9h 53m

$370

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 4/29

1:36 pm-12:10 am

1 stop7h 34m

Roanoke

Sat 5/2

7:00 am-2:21 pm

2 stops10h 21m

$375

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 7/1

12:01 pm-10:59 pm

1 stop7h 58m

Roanoke

Tue 7/7

7:00 am-12:05 pm

1 stop8h 05m

$417

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 4/29

10:50 am-11:44 pm

2 stops9h 54m

Roanoke

Sat 5/2

6:45 am-2:22 pm

2 stops10h 37m

$424

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Fri 4/10

1:36 pm-12:10 am

1 stop7h 34m

Roanoke

Sun 4/12

7:28 am-2:21 pm

1 stop9h 53m

$487

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 7/1

12:01 pm-10:59 pm

1 stop7h 58m

Roanoke

Tue 7/7

8:00 am-3:38 pm

2 stops10h 38m

$538

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Fri 4/10

1:36 pm-12:10 am

1 stop7h 34m

Roanoke

Sun 4/12

5:00 am-12:38 pm

2 stops10h 38m

$553

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 7/1

6:45 am-7:33 pm

2 stops9h 48m

Roanoke

Tue 7/7

7:00 am-1:39 pm

1 stop9h 39m

$563

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 7/1

6:20 pm-10:12 am

2 stops12h 52m

Roanoke

Tue 7/7

6:40 am-9:05 am

2 stops29h 25m

$568

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Roanoke from

How to get the cheapest flight ticket from Santa Ana to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Santa Ana to Roanoke flights?

You could potentially save up to 43% on your flight if you consider stops on a Santa Ana to Roanoke flight.

When to book flights from Santa Ana to Roanoke

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Roanoke according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Roanoke (SNA to ROA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Roanoke

Fastest flight time

6h 49m

Direct flights

None
The fastest flight from Santa Ana to Roanoke takes 6h 49m
There are no direct flights from Santa Ana to Roanoke. There are no popular flight routes from Santa Ana to Roanoke.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Roanoke by plane?

    There are 2131.2 mi between Santa Ana J. Wayne/Orange Cnty and Roanoke. In terms of flight time, this usually takes a little over 6h 49m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport.

  • What documentation or ID do you need to fly to Roanoke Airport?

    The travel and health documents required for your trip to Roanoke Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Roanoke Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana to Roanoke?

Best airlines flying from Santa Ana to Roanoke

Compare and see reviews for airlines that fly from Santa Ana to Roanoke with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.2
11,357 reviews
Search American Airlines flights
United AirlinesPriceFrom $453Free CancellationRating
7.4
9,349 reviews
Search United Airlines flights

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Blacksburg
Salem
Christiansburg
Radford
Rocky Mount

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Roanoke?

It is quick and easy to find Santa Ana to Roanoke flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Roanoke that suits you.

Can I find flights from Santa Ana to Roanoke with flexible booking policies on momondo?

Yes. All flights to Roanoke from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to Roanoke?

momondo provides multiple filters to help you find the best flight to Roanoke from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Roanoke right now. Can momondo alert me if prices change?

Price alerts on flights to Roanoke from Santa Ana are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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