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Cheap flights from Santa Ana to Roanoke from $338

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Roanoke departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana to Roanoke

Cheap round-trip flights

United Airlines Logo
10:30 am - 11:24 pmSNA-ROA
9h 54m2 stops
United Airlines Logo
6:45 am - 11:38 amROA-SNA
7h 53m1 stop
$374United Airlines
Find Deal
Wed, Sep 3 - Sat, Sep 6
United Airlines Logo
7:00 pm - 10:06 amSNA-ROA
12h 06m2 stops
United Airlines Logo
6:20 am - 12:44 pmROA-SNA
9h 24m2 stops
$379United Airlines
Find Deal
Wed, Sep 3 - Sat, Sep 6
Delta Logo
1:52 pm - 12:25 amSNA-ROA
7h 33m1 stop
Delta Logo
3:42 pm - 10:28 pmROA-SNA
9h 46m1 stop
$384Delta
Find Deal
Tue, Sep 30 - Fri, Oct 10
American Airlines Logo
11:35 am - 10:12 pmSNA-ROA
7h 37m1 stop
American Airlines Logo
8:21 am - 3:45 pmROA-SNA
10h 24m2 stops
$389American Airlines
Find Deal
Thu, Sep 11 - Tue, Sep 16
Delta Logo
1:52 pm - 12:25 amSNA-ROA
7h 33m1 stop
Delta Logo
3:42 pm - 10:28 pmROA-SNA
9h 46m1 stop
$404Delta
Find Deal
Tue, Sep 30 - Wed, Oct 8
Delta Logo
8:00 am - 11:57 pmSNA-ROA
12h 57m2 stops
Delta Logo
3:42 pm - 10:28 pmROA-SNA
9h 46m1 stop
$409Delta
Find Deal
Sat, Oct 4 - Wed, Oct 8
United Airlines Logo
8:00 am - 11:24 pmSNA-ROA
12h 24m2 stops
United Airlines Logo
6:45 am - 11:40 amROA-SNA
7h 55m1 stop
$414United Airlines
Find Deal
Thu, Sep 11 - Tue, Sep 16
American Airlines Logo
11:35 am - 10:12 pmSNA-ROA
7h 37m1 stop
American Airlines Logo
7:01 am - 2:20 pmROA-SNA
10h 19m1 stop
$418American Airlines
Find Deal
Thu, Sep 11 - Tue, Sep 16
American Airlines Logo
7:30 am - 6:37 pmSNA-ROA
8h 07m1 stop
American Airlines Logo
3:01 pm - 7:51 pmROA-SNA
7h 50m1 stop
$448American Airlines
Find Deal
Wed, Sep 3 - Sat, Sep 6
American Airlines Logo
7:30 am - 6:37 pmSNA-ROA
8h 07m1 stop
American Airlines Logo
2:23 pm - 9:26 pmROA-SNA
10h 03m2 stops
$454American Airlines
Find Deal
Mon, Sep 29 - Sat, Oct 11

United Airlines flights from Santa Ana to Roanoke

Our best United Airlines deals on Santa Ana to Roanoke flight tickets
United Airlines
Sep 3
SNA10:30 amSanta Ana J. Wayne/Orange Cnty
9h 54m
2 stops
ROA11:24 pmRoanoke
Sep 6
ROA6:45 amRoanoke
7h 53m
1 stop
SNA11:38 amSanta Ana J. Wayne/Orange Cnty
$374
Find similar
United Airlines
Sep 3
SNA7:00 pmSanta Ana J. Wayne/Orange Cnty
12h 06m
2 stops
ROA10:06 amRoanoke
Sep 6
ROA6:20 amRoanoke
9h 24m
2 stops
SNA12:44 pmSanta Ana J. Wayne/Orange Cnty
$379
Find similar
United Airlines
Sep 11
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
12h 24m
2 stops
ROA11:24 pmRoanoke
Sep 16
ROA6:45 amRoanoke
7h 55m
1 stop
SNA11:40 amSanta Ana J. Wayne/Orange Cnty
$414
Find similar

American Airlines flights from Santa Ana to Roanoke

Our best American Airlines deals on Santa Ana to Roanoke flight tickets
American Airlines
Sep 11
SNA11:35 amSanta Ana J. Wayne/Orange Cnty
7h 37m
1 stop
ROA10:12 pmRoanoke
Sep 16
ROA8:21 amRoanoke
10h 24m
2 stops
SNA3:45 pmSanta Ana J. Wayne/Orange Cnty
$389
Find similar
American Airlines
Sep 11
SNA11:35 amSanta Ana J. Wayne/Orange Cnty
7h 37m
1 stop
ROA10:12 pmRoanoke
Sep 16
ROA7:01 amRoanoke
10h 19m
1 stop
SNA2:20 pmSanta Ana J. Wayne/Orange Cnty
$418
Find similar
American Airlines
Sep 3
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
8h 07m
1 stop
ROA6:37 pmRoanoke
Sep 6
ROA3:01 pmRoanoke
7h 50m
1 stop
SNA7:51 pmSanta Ana J. Wayne/Orange Cnty
$448
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Santa Ana to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 9/3

10:30 am-11:24 pm

2 stops9h 54m

Roanoke

Sat 9/6

6:45 am-11:38 am

1 stop7h 53m

$374

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 9/3

7:00 pm-10:06 am

2 stops12h 06m

Roanoke

Sat 9/6

6:20 am-12:44 pm

2 stops9h 24m

$379

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Tue 9/30

1:52 pm-12:25 am

1 stop7h 33m

Roanoke

Fri 10/10

3:42 pm-10:28 pm

1 stop9h 46m

$384

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Thu 9/11

11:35 am-10:12 pm

1 stop7h 37m

Roanoke

Tue 9/16

8:21 am-3:45 pm

2 stops10h 24m

$389

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Tue 9/30

1:52 pm-12:25 am

1 stop7h 33m

Roanoke

Wed 10/8

3:42 pm-10:28 pm

1 stop9h 46m

$404

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Sat 10/4

8:00 am-11:57 pm

2 stops12h 57m

Roanoke

Wed 10/8

3:42 pm-10:28 pm

1 stop9h 46m

$409

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Thu 9/11

8:00 am-11:24 pm

2 stops12h 24m

Roanoke

Tue 9/16

6:45 am-11:40 am

1 stop7h 55m

$414

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Thu 9/11

11:35 am-10:12 pm

1 stop7h 37m

Roanoke

Tue 9/16

7:01 am-2:20 pm

1 stop10h 19m

$418

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 9/3

7:30 am-6:37 pm

1 stop8h 07m

Roanoke

Sat 9/6

3:01 pm-7:51 pm

1 stop7h 50m

$448

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Mon 9/29

7:30 am-6:37 pm

1 stop8h 07m

Roanoke

Sat 10/11

2:23 pm-9:26 pm

2 stops10h 03m

$454

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Roanoke from

How to get the cheapest flight ticket from Santa Ana to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Roanoke?

Our data shows that Wednesday is the least expensive day to fly to Roanoke. Tickets to fly out on this day can be as low as $481. Flights from Santa Ana to Roanoke on a Sunday will generally be more expensive and average around $684. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Roanoke?

Our most recent data shows that the best time of day to fly to Roanoke is at noon. Flights from Santa Ana to Roanoke during this time can be as low as $476. In contrast, the most expensive time of day to depart to Roanoke is in the evening when prices are around $516.

When to book flights from Santa Ana to Roanoke

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Roanoke according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Roanoke (SNA to ROA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Roanoke

Direct flights

None
There are no direct flights from Santa Ana to Roanoke. There are no popular flight routes from Santa Ana to Roanoke.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Roanoke by plane?

    There are 2131.2 mi between Santa Ana J. Wayne/Orange Cnty and Roanoke. In terms of flight time, this usually takes a little over 7h 33m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport.

  • What documentation or ID do you need to fly to Roanoke Airport?

    The travel and health documents required for your trip to Roanoke Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Roanoke Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana to Roanoke?

Best airlines flying from Santa Ana to Roanoke

Compare and see reviews for airlines that fly from Santa Ana to Roanoke with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $345Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $408Free CancellationRating
7.4
8,930 reviews
Search United Airlines flights

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Salem
Christiansburg
Blacksburg
Radford
Rocky Mount
Lafayette

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Roanoke?

It is quick and easy to find Santa Ana to Roanoke flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Roanoke that suits you.

Can I find flights from Santa Ana to Roanoke with flexible booking policies on momondo?

Yes. All flights to Roanoke from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to Roanoke?

momondo provides multiple filters to help you find the best flight to Roanoke from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Roanoke right now. Can momondo alert me if prices change?

Price alerts on flights to Roanoke from Santa Ana are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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