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Cheap flights from Santa Ana to Roanoke from $275

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Roanoke departing on 10/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana to Roanoke

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:00 pm - 11:50 pm
SNA
-
ROA
6h 50m
1 stop
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
$377Delta
Wed, Aug 5 - Sat, Aug 15
Delta Logo
2:00 pm - 11:50 pm
SNA
-
ROA
6h 50m
1 stop
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
$393Delta
Thu, Aug 6 - Sat, Aug 15
American Airlines Logo
9:46 am - 10:59 pm
SNA
-
ROA
10h 13m
2 stops
American Airlines Logo
7:00 am - 3:33 pm
ROA
-
SNA
11h 33m
2 stops
$416American Airlines
Wed, Jul 1 - Tue, Jul 7
Delta Logo
12:15 pm - 11:50 pm
SNA
-
ROA
8h 35m
1 stop
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
$423Delta
Wed, Aug 5 - Fri, Aug 14
American Airlines Logo
12:01 pm - 10:59 pm
SNA
-
ROA
7h 58m
1 stop
American Airlines Logo
7:00 am - 3:34 pm
ROA
-
SNA
11h 34m
2 stops
$427American Airlines
Sat, Jun 6 - Sat, Jun 20
American Airlines Logo
9:46 am - 10:59 pm
SNA
-
ROA
10h 13m
2 stops
American Airlines Logo
7:00 am - 3:34 pm
ROA
-
SNA
11h 34m
2 stops
$432American Airlines
Sat, Jun 6 - Sat, Jun 20
Delta Logo
2:00 pm - 11:50 pm
SNA
-
ROA
6h 50m
1 stop
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
$439Delta
Thu, Aug 6 - Fri, Aug 14
American Airlines Logo
9:46 am - 10:59 pm
SNA
-
ROA
10h 13m
2 stops
American Airlines Logo
7:00 am - 3:33 pm
ROA
-
SNA
11h 33m
2 stops
$446American Airlines
Wed, Jul 1 - Tue, Jul 7
American Airlines Logo
10:00 am - 11:59 pm
SNA
-
ROA
10h 59m
2 stops
American Airlines Logo
4:09 pm - 8:00 pm
ROA
-
SNA
6h 51m
1 stop
$448American Airlines
Thu, Aug 6 - Sat, Aug 15
American Airlines Logo
12:01 pm - 10:59 pm
SNA
-
ROA
7h 58m
1 stop
American Airlines Logo
7:00 am - 12:11 pm
ROA
-
SNA
8h 11m
1 stop
$452American Airlines
Sat, Jun 6 - Sat, Jun 20

American Airlines flights from Santa Ana to Roanoke

Our best American Airlines deals on Santa Ana to Roanoke flight tickets
American Airlines
Jul 1
SNA9:46 amSanta Ana J. Wayne/Orange Cnty
10h 13m
2 stops
ROA10:59 pmRoanoke
Jul 7
ROA7:00 amRoanoke
11h 33m
2 stops
SNA3:33 pmSanta Ana J. Wayne/Orange Cnty
$416
American Airlines
Jun 6
SNA12:01 pmSanta Ana J. Wayne/Orange Cnty
7h 58m
1 stop
ROA10:59 pmRoanoke
Jun 20
ROA7:00 amRoanoke
11h 34m
2 stops
SNA3:34 pmSanta Ana J. Wayne/Orange Cnty
$427
American Airlines
Jun 6
SNA9:46 amSanta Ana J. Wayne/Orange Cnty
10h 13m
2 stops
ROA10:59 pmRoanoke
Jun 20
ROA7:00 amRoanoke
11h 34m
2 stops
SNA3:34 pmSanta Ana J. Wayne/Orange Cnty
$432

United Airlines flights from Santa Ana to Roanoke

Our best United Airlines deals on Santa Ana to Roanoke flight tickets
United Airlines
Aug 5
SNA2:10 pmSanta Ana J. Wayne/Orange Cnty
7h 39m
1 stop
ROA12:49 amRoanoke
Aug 14
ROA6:15 amRoanoke
10h 47m
2 stops
SNA2:02 pmSanta Ana J. Wayne/Orange Cnty
$498
United Airlines
Aug 6
SNA2:10 pmSanta Ana J. Wayne/Orange Cnty
7h 39m
1 stop
ROA12:49 amRoanoke
Aug 15
ROA10:30 amRoanoke
14h 23m
2 stops
SNA9:53 pmSanta Ana J. Wayne/Orange Cnty
$617
United Airlines
Apr 23
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
10h 27m
2 stops
ROA12:37 amRoanoke
Apr 25
ROA8:37 amRoanoke
10h 21m
2 stops
SNA3:58 pmSanta Ana J. Wayne/Orange Cnty
$630

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 13, 2026.
Use the filters below to find and compare flights from Santa Ana to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 8/5

2:00 pm-11:50 pm

1 stop6h 50m

Roanoke

Sat 8/15

3:25 pm-10:14 pm

1 stop9h 49m

$377

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Thu 8/6

2:00 pm-11:50 pm

1 stop6h 50m

Roanoke

Sat 8/15

3:25 pm-10:14 pm

1 stop9h 49m

$393

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 7/1

9:46 am-10:59 pm

2 stops10h 13m

Roanoke

Tue 7/7

7:00 am-3:33 pm

2 stops11h 33m

$416

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 8/5

12:15 pm-11:50 pm

1 stop8h 35m

Roanoke

Fri 8/14

3:25 pm-10:14 pm

1 stop9h 49m

$423

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Sat 6/6

12:01 pm-10:59 pm

1 stop7h 58m

Roanoke

Sat 6/20

7:00 am-3:34 pm

2 stops11h 34m

$427

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Sat 6/6

9:46 am-10:59 pm

2 stops10h 13m

Roanoke

Sat 6/20

7:00 am-3:34 pm

2 stops11h 34m

$432

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Thu 8/6

2:00 pm-11:50 pm

1 stop6h 50m

Roanoke

Fri 8/14

3:25 pm-10:14 pm

1 stop9h 49m

$439

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Wed 7/1

9:46 am-10:59 pm

2 stops10h 13m

Roanoke

Tue 7/7

7:00 am-3:33 pm

2 stops11h 33m

$446

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Thu 8/6

10:00 am-11:59 pm

2 stops10h 59m

Roanoke

Sat 8/15

4:09 pm-8:00 pm

1 stop6h 51m

$448
Quickest round-trip

Santa AnaRoanoke

SNA - ROA

SNAROA

Santa Ana J. Wayne/Orange Cnty

Sat 6/6

12:01 pm-10:59 pm

1 stop7h 58m

Roanoke

Sat 6/20

7:00 am-12:11 pm

1 stop8h 11m

$452

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santa Ana to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Santa Ana to Roanoke flights?

You could potentially save up to 43% on your flight if you consider stops on a Santa Ana to Roanoke flight.

When to book flights from Santa Ana to Roanoke

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Roanoke according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Roanoke (SNA to ROA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Roanoke

Fastest flight time

6h 50m

Direct flights

None
The fastest flight from Santa Ana to Roanoke takes 6h 50m
There are no direct flights from Santa Ana to Roanoke. There are no popular flight routes from Santa Ana to Roanoke.
Search flight deals

Frequently asked questions about flying from Santa Ana to Roanoke

  • How far is Santa Ana J. Wayne/Orange Cnty to Roanoke by plane?

    There are 2131.2 mi between Santa Ana J. Wayne/Orange Cnty and Roanoke. In terms of flight time, this usually takes a little over 6h 50m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Roanoke Airport.

  • What documentation or ID do you need to fly to Roanoke Airport?

    The travel and health documents required for your trip to Roanoke Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Roanoke Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana to Roanoke?

Best airlines flying from Santa Ana to Roanoke

Compare and see reviews for airlines that fly from Santa Ana to Roanoke with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,569 reviews
Search American Airlines flights
United AirlinesPriceFrom $453Free CancellationRating
7.4
9,579 reviews
Search United Airlines flights

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Blacksburg
Salem
Christiansburg
Radford
Rocky Mount

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Roanoke?

It is quick and easy to find Santa Ana to Roanoke flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Roanoke that suits you.

Can I find flights from Santa Ana to Roanoke with flexible booking policies on momondo?

Yes. All flights to Roanoke from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to Roanoke?

momondo provides multiple filters to help you find the best flight to Roanoke from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Roanoke right now. Can momondo alert me if prices change?

Price alerts on flights to Roanoke from Santa Ana are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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